RAB7B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)5.92787314
2axon ensheathment in central nervous system (GO:0032291)5.92787314
3modulation by symbiont of host immune response (GO:0052553)5.76927787
4positive regulation by symbiont of host defense response (GO:0052509)5.76927787
5modulation by symbiont of host defense response (GO:0052031)5.76927787
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.76927787
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.76927787
8positive regulation by organism of defense response of other organism involved in symbiotic interact5.76927787
9neutrophil activation involved in immune response (GO:0002283)5.60080989
10negative regulation of interleukin-12 production (GO:0032695)5.11975783
11regulation of vitamin D biosynthetic process (GO:0060556)5.04469567
12oligosaccharide catabolic process (GO:0009313)4.77528468
13fatty acid elongation (GO:0030497)4.55813304
14respiratory burst (GO:0045730)4.41117139
15microglial cell activation (GO:0001774)4.38930192
16regulation of interferon-beta biosynthetic process (GO:0045357)4.36775183
17response to lipoprotein particle (GO:0055094)4.22173543
18positive regulation of chemokine biosynthetic process (GO:0045080)4.18983731
19antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.17136237
20negative regulation of nitric oxide biosynthetic process (GO:0045019)4.08790306
21amino sugar catabolic process (GO:0046348)4.01414895
22macrophage activation involved in immune response (GO:0002281)3.99926405
23long-chain fatty acid biosynthetic process (GO:0042759)3.99524981
24regulation of vitamin metabolic process (GO:0030656)3.96602503
25positive regulation of heat generation (GO:0031652)3.95537776
26positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.93620241
27amyloid precursor protein metabolic process (GO:0042982)3.87813188
28import into cell (GO:0098657)3.81813171
29regulation of fever generation (GO:0031620)3.78870126
30regulation of podosome assembly (GO:0071801)3.78855458
31response to peptidoglycan (GO:0032494)3.75925885
32regulation of chemokine biosynthetic process (GO:0045073)3.75770112
33pinocytosis (GO:0006907)3.75547290
34positive regulation of monocyte chemotaxis (GO:0090026)3.72508836
35leukocyte migration involved in inflammatory response (GO:0002523)3.70899703
36regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.70681591
37regulation of cytokine secretion involved in immune response (GO:0002739)3.67754200
38positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.66294775
39positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.63128579
40amyloid precursor protein catabolic process (GO:0042987)3.63076864
41membrane raft organization (GO:0031579)3.62780631
42membrane lipid catabolic process (GO:0046466)3.61197726
43myeloid dendritic cell differentiation (GO:0043011)3.59247259
44myeloid cell activation involved in immune response (GO:0002275)3.55687697
45T-helper 1 type immune response (GO:0042088)3.55665809
46response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.52889193
47response to host immune response (GO:0052572)3.52889193
48neutrophil activation (GO:0042119)3.52589459
49ensheathment of neurons (GO:0007272)3.52375180
50axon ensheathment (GO:0008366)3.52375180
51myelination (GO:0042552)3.48424177
52granulocyte activation (GO:0036230)3.46432490
53positive regulation of antigen processing and presentation (GO:0002579)3.45720074
54regulation of cholesterol storage (GO:0010885)3.44483813
55sphingolipid catabolic process (GO:0030149)3.43570051
56NIK/NF-kappaB signaling (GO:0038061)3.43163803
57response to thyroid hormone (GO:0097066)3.43076971
58regulation of membrane protein ectodomain proteolysis (GO:0051043)3.40161461
59L-amino acid import (GO:0043092)3.34735454
60regulation of chronic inflammatory response (GO:0002676)3.34608374
61positive regulation of interferon-alpha production (GO:0032727)3.33958666
62immunoglobulin mediated immune response (GO:0016064)3.33800545
63regulation of T-helper 1 cell differentiation (GO:0045625)3.33522276
64intracellular pH reduction (GO:0051452)3.28186313
65positive regulation of toll-like receptor signaling pathway (GO:0034123)3.27980824
66regulation of T cell migration (GO:2000404)3.26760795
67negative regulation of cytokine production involved in immune response (GO:0002719)3.25218185
68barbed-end actin filament capping (GO:0051016)3.22120657
69glycosylceramide metabolic process (GO:0006677)3.22004129
70regulation of B cell receptor signaling pathway (GO:0050855)3.21333708
71myeloid dendritic cell activation (GO:0001773)3.18488795
72regulation of interferon-alpha production (GO:0032647)3.18399245
73regulation of macrophage chemotaxis (GO:0010758)3.17468929
74macrophage activation (GO:0042116)3.14745655
75glycosphingolipid catabolic process (GO:0046479)3.12999515
76regulation of antigen processing and presentation (GO:0002577)3.12989500
77adhesion of symbiont to host cell (GO:0044650)3.11267756
78virion attachment to host cell (GO:0019062)3.11267756
79positive regulation of T cell migration (GO:2000406)3.08524314
80regulation of mononuclear cell migration (GO:0071675)3.07398095
81negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.07373602
82positive regulation of mast cell activation (GO:0033005)3.06580931
83branching involved in labyrinthine layer morphogenesis (GO:0060670)3.06141326
84negative regulation of myeloid cell apoptotic process (GO:0033033)3.05908067
85N-acetylneuraminate metabolic process (GO:0006054)3.05168673
86regulation of lymphocyte migration (GO:2000401)3.04583334
87regulation of monocyte chemotaxis (GO:0090025)3.01538876
88regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.01385397
89interferon-gamma-mediated signaling pathway (GO:0060333)3.00692976
90regulation of interleukin-8 biosynthetic process (GO:0045414)2.98670836
91myelin maintenance (GO:0043217)2.97664900
92regulation of heat generation (GO:0031650)2.97042593
93dendritic cell differentiation (GO:0097028)2.96935637
94pH reduction (GO:0045851)2.96761464
95response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.94844907
96response to host (GO:0075136)2.94844907
97response to host defenses (GO:0052200)2.94844907
98cellular response to lipopolysaccharide (GO:0071222)2.92951747
99regulation of collateral sprouting (GO:0048670)2.92768821
100germinal center formation (GO:0002467)2.92009569
101regulation of nitric oxide biosynthetic process (GO:0045428)2.91790140
102low-density lipoprotein particle clearance (GO:0034383)2.90642701
103response to protozoan (GO:0001562)2.85874727
104positive regulation of gamma-delta T cell activation (GO:0046645)2.85409585
105positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.83719324
106cellular response to thyroid hormone stimulus (GO:0097067)2.83618556
107positive regulation of mast cell activation involved in immune response (GO:0033008)2.83592663
108positive regulation of mast cell degranulation (GO:0043306)2.83592663
109neutrophil mediated immunity (GO:0002446)2.83228743
110superoxide anion generation (GO:0042554)2.82973170
111negative regulation of erythrocyte differentiation (GO:0045647)2.82961431
112cellular response to type I interferon (GO:0071357)2.82691367
113type I interferon signaling pathway (GO:0060337)2.82691367
114cellular response to molecule of bacterial origin (GO:0071219)2.81939648
115negative regulation of lipid storage (GO:0010888)2.81792358
116macrophage differentiation (GO:0030225)2.81623806
117phagosome maturation (GO:0090382)2.81216132
118positive regulation of lymphocyte migration (GO:2000403)2.81030379
119positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.80560596
120decidualization (GO:0046697)2.79557519
121glycolipid catabolic process (GO:0019377)2.79512706
122negative regulation of mast cell activation (GO:0033004)2.79501707
123regulation of mast cell activation (GO:0033003)2.78752869
124response to type I interferon (GO:0034340)2.78180687
125regulation of inflammatory response to antigenic stimulus (GO:0002861)2.76500143
126response to muramyl dipeptide (GO:0032495)2.75376012
127positive regulation of NF-kappaB import into nucleus (GO:0042346)2.75217245
128ceramide catabolic process (GO:0046514)2.74841999
129detection of molecule of bacterial origin (GO:0032490)2.73050532
130regulation of dendritic cell antigen processing and presentation (GO:0002604)2.71780864
131positive regulation of macrophage cytokine production (GO:0060907)2.71664099
132leukocyte degranulation (GO:0043299)2.71645626
133mast cell activation (GO:0045576)2.71288236
134regulation of leukocyte degranulation (GO:0043300)2.71061359
135cellular response to arsenic-containing substance (GO:0071243)2.70593983
136regulation of T-helper 2 cell differentiation (GO:0045628)2.69391440
137positive regulation of oligodendrocyte differentiation (GO:0048714)2.68889459
138Rap protein signal transduction (GO:0032486)2.66708711
139regulation of mast cell activation involved in immune response (GO:0033006)2.66293701
140defense response to protozoan (GO:0042832)2.65489451
141regulation of interleukin-12 production (GO:0032655)2.63969575
142positive regulation of cellular amide metabolic process (GO:0034250)2.63950333
143regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.63641374
144cholesterol biosynthetic process (GO:0006695)2.61630359
145negative regulation of production of molecular mediator of immune response (GO:0002701)2.61452485
146myeloid leukocyte activation (GO:0002274)2.60113619
147regulation of mast cell degranulation (GO:0043304)2.59805229
148protein localization to endosome (GO:0036010)2.58314221
149amino acid import (GO:0043090)2.56341026
150positive regulation of leukocyte degranulation (GO:0043302)2.52425997
151monocyte chemotaxis (GO:0002548)2.50240172
152positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.50113197
153regulation of neutrophil migration (GO:1902622)2.49447054
154regulation of neutrophil chemotaxis (GO:0090022)2.49447054
155negative regulation of neurotransmitter secretion (GO:0046929)2.49061628
156leukocyte aggregation (GO:0070486)2.48630488
157lymphocyte chemotaxis (GO:0048247)2.48149334
158adhesion of symbiont to host (GO:0044406)2.48143220
159response to methylmercury (GO:0051597)2.46923564
160negative regulation of interleukin-8 production (GO:0032717)2.43258952
161phagocytosis, engulfment (GO:0006911)2.42561607
162membrane protein ectodomain proteolysis (GO:0006509)2.42534964
163lipopolysaccharide-mediated signaling pathway (GO:0031663)2.42453382
164eosinophil chemotaxis (GO:0048245)2.42400495

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse6.18612697
2BP1_19119308_ChIP-ChIP_Hs578T_Human5.47047553
3IRF8_27001747_Chip-Seq_BMDM_Mouse4.18911572
4Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.84565164
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.81003656
6IRF8_22096565_ChIP-ChIP_GC-B_Human3.80571413
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.53004591
8NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.17596820
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.01067832
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.51439674
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.44775441
12VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.35542610
13MYB_21317192_ChIP-Seq_ERMYB_Mouse2.29109105
14IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.25500005
15VDR_21846776_ChIP-Seq_THP-1_Human2.25386065
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.23955053
17TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.21038563
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.09608822
19TRIM28_21343339_ChIP-Seq_HEK293_Human2.01193919
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.99405425
21CDX2_19796622_ChIP-Seq_MESCs_Mouse1.97611353
22VDR_24787735_ChIP-Seq_THP-1_Human1.90338972
23SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.86755431
24NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.83590329
25PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.81779954
26NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.80858695
27RARG_19884340_ChIP-ChIP_MEFs_Mouse1.75017962
28LXR_22292898_ChIP-Seq_THP-1_Human1.72879451
29RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.69325850
30STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.69293715
31ELK3_25401928_ChIP-Seq_HUVEC_Human1.68576631
32NRF2_20460467_ChIP-Seq_MEFs_Mouse1.62366421
33NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.62366421
34SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.61526679
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.58929172
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57612704
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.57047900
38KDM2B_26808549_Chip-Seq_SUP-B15_Human1.55603135
39STAT4_19710469_ChIP-ChIP_TH1__Mouse1.54757709
40SPI1_23547873_ChIP-Seq_NB4_Human1.51892633
41PU_27001747_Chip-Seq_BMDM_Mouse1.50672691
42IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.49864811
43SPI1_23127762_ChIP-Seq_K562_Human1.48328813
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.48326957
45CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.46097902
46TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45576275
47STAT6_21828071_ChIP-Seq_BEAS2B_Human1.44560903
48RUNX_20019798_ChIP-Seq_JUKART_Human1.44537888
49GATA2_21666600_ChIP-Seq_HMVEC_Human1.42911388
50WT1_19549856_ChIP-ChIP_CCG9911_Human1.42648511
51* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40124490
52VDR_24763502_ChIP-Seq_THP-1_Human1.37572742
53ESR2_21235772_ChIP-Seq_MCF-7_Human1.37322341
54E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35055599
55TFEB_21752829_ChIP-Seq_HELA_Human1.33231060
56P63_26484246_Chip-Seq_KERATINOCYTES_Human1.33174272
57CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.31379419
58CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.28074899
59CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.27458561
60PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.25576494
61* SOX2_20726797_ChIP-Seq_SW620_Human1.23769668
62FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.23288700
63AR_21572438_ChIP-Seq_LNCaP_Human1.21225638
64MAF_26560356_Chip-Seq_TH1_Human1.20528653
65EGR1_19032775_ChIP-ChIP_M12_Human1.20328622
66PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19962807
67CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19911955
68CJUN_26792858_Chip-Seq_BT549_Human1.18769395
69PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16632453
70TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.15595560
71MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.15580669
72RUNX1_22412390_ChIP-Seq_EML_Mouse1.14053170
73KDM2B_26808549_Chip-Seq_DND41_Human1.13764042
74KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.13405508
75GATA1_19941827_ChIP-Seq_MEL_Mouse1.13279318
76SCL_19346495_ChIP-Seq_HPC-7_Human1.13009767
77ER_23166858_ChIP-Seq_MCF-7_Human1.11401650
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.11373253
79FOXO3_23340844_ChIP-Seq_DLD1_Human1.09650186
80TCF7_22412390_ChIP-Seq_EML_Mouse1.08657438
81CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.07677299
82STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.06538469
83PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06440107
84SMAD_19615063_ChIP-ChIP_OVARY_Human1.06366590
85LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.04842477
86STAT1_20625510_ChIP-Seq_HELA_Human1.04372364
87TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03434830
88GATA1_22025678_ChIP-Seq_K562_Human1.03073575
89TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02083199
90RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.01773792
91FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.01480466
92RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00872831
93JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99067071
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.98753444
95SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97889474
96GATA3_26560356_Chip-Seq_TH2_Human0.97203569
97KDM2B_26808549_Chip-Seq_K562_Human0.96950764
98CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96820853
99RXR_22158963_ChIP-Seq_LIVER_Mouse0.96660957
100SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96580114
101CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96402566
102CLOCK_20551151_ChIP-Seq_293T_Human0.95778767
103EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.95236898
104KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.95086464
105RACK7_27058665_Chip-Seq_MCF-7_Human0.93989464
106RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93064731
107MYB_26560356_Chip-Seq_TH2_Human0.92733557
108PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.92498337
109GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91381804
110FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.90505196
111UTX_26944678_Chip-Seq_JUKART_Human0.90224962
112SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88979231
113ESR1_21235772_ChIP-Seq_MCF-7_Human0.87206321
114TP63_23658742_ChIP-Seq_EP156T_Human0.87165916
115TP53_18474530_ChIP-ChIP_U2OS_Human0.86686514
116BCOR_27268052_Chip-Seq_Bcells_Human0.85940772
117PPARA_22158963_ChIP-Seq_LIVER_Mouse0.85874375
118GATA1_22383799_ChIP-Seq_G1ME_Mouse0.85754436
119SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85650289
120BCL6_27268052_Chip-Seq_Bcells_Human0.85463325
121MAF_26560356_Chip-Seq_TH2_Human0.84890851
122FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.80738543
123OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79914946
124ZFP57_27257070_Chip-Seq_ESCs_Mouse0.78949791
125JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.77789112
126SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.76897486
127SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.75372175
128SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.75372175
129GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.72379152
130CMYC_18555785_Chip-Seq_ESCs_Mouse0.72242744
131LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.71269186
132THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.70394790
133GATA3_27048872_Chip-Seq_THYMUS_Human0.69216528
134SUZ12_18555785_Chip-Seq_ESCs_Mouse0.67836230
135ZNF217_24962896_ChIP-Seq_MCF-7_Human0.67082717
136TP53_16413492_ChIP-PET_HCT116_Human0.66584480
137PPAR_26484153_Chip-Seq_NCI-H1993_Human0.65788682
138SMRT_27268052_Chip-Seq_Bcells_Human0.65746184
139GATA2_19941826_ChIP-Seq_K562_Human0.63859343
140GATA1_19941826_ChIP-Seq_K562_Human0.63821554
141GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.63275394

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.33713721
2MP0000920_abnormal_myelination3.76673443
3MP0001835_abnormal_antigen_presentation3.72118668
4MP0006082_CNS_inflammation3.50149271
5MP0003690_abnormal_glial_cell3.38005473
6MP0003303_peritoneal_inflammation3.13348886
7MP0003436_decreased_susceptibility_to2.88078163
8MP0002419_abnormal_innate_immunity2.85242244
9MP0002148_abnormal_hypersensitivity_rea2.82192369
10MP0002139_abnormal_hepatobiliary_system2.80470584
11MP0005000_abnormal_immune_tolerance2.58880628
12MP0003136_yellow_coat_color2.44165620
13MP0003950_abnormal_plasma_membrane2.37748181
14MP0003172_abnormal_lysosome_physiology2.35296645
15MP0004381_abnormal_hair_follicle2.23513482
16MP0000604_amyloidosis2.23138691
17MP0005025_abnormal_response_to2.22834803
18MP0009785_altered_susceptibility_to2.19988070
19MP0008438_abnormal_cutaneous_collagen2.11002013
20MP0000383_abnormal_hair_follicle2.10081603
21MP0001790_abnormal_immune_system2.08746538
22MP0005387_immune_system_phenotype2.08746538
23MP0003724_increased_susceptibility_to2.08181904
24MP0002452_abnormal_antigen_presenting2.04234699
25MP0001851_eye_inflammation1.99116328
26MP0009278_abnormal_bone_marrow1.93828448
27MP0001533_abnormal_skeleton_physiology1.88232259
28MP0002723_abnormal_immune_serum1.83224221
29MP0010678_abnormal_skin_adnexa1.76463441
30MP0006054_spinal_hemorrhage1.75229104
31MP0008004_abnormal_stomach_pH1.74256699
32MP0005397_hematopoietic_system_phenotyp1.70287718
33MP0001545_abnormal_hematopoietic_system1.70287718
34MP0001800_abnormal_humoral_immune1.67766540
35MP0005257_abnormal_intraocular_pressure1.66280360
36MP0001819_abnormal_immune_cell1.65421297
37MP0005171_absent_coat_pigmentation1.65215666
38MP0002420_abnormal_adaptive_immunity1.63296859
39MP0005409_darkened_coat_color1.62995445
40MP0005451_abnormal_body_composition1.62450841
41MP0005167_abnormal_blood-brain_barrier1.60771724
42MP0005671_abnormal_response_to1.59517929
43MP0003634_abnormal_glial_cell1.59130479
44MP0009840_abnormal_foam_cell1.56541443
45MP0003806_abnormal_nucleotide_metabolis1.56425263
46MP0003075_altered_response_to1.52821334
47MP0000685_abnormal_immune_system1.52257673
48MP0003448_altered_tumor_morphology1.51668544
49MP0000343_altered_response_to1.50422865
50MP0004510_myositis1.48644502
51MP0000858_altered_metastatic_potential1.46087791
52MP0005464_abnormal_platelet_physiology1.45921923
53MP0005310_abnormal_salivary_gland1.40803274
54MP0002998_abnormal_bone_remodeling1.40208960
55MP0000465_gastrointestinal_hemorrhage1.38589573
56MP0004947_skin_inflammation1.32966156
57MP0002090_abnormal_vision1.31264716
58MP0002933_joint_inflammation1.29522519
59MP0000647_abnormal_sebaceous_gland1.28290684
60MP0002405_respiratory_system_inflammati1.26804790
61MP0008260_abnormal_autophagy1.24236599
62MP0003191_abnormal_cellular_cholesterol1.23412857
63MP0003453_abnormal_keratinocyte_physiol1.21699676
64MP0004742_abnormal_vestibular_system1.21411029
65MP0001845_abnormal_inflammatory_respons1.20031385
66MP0000372_irregular_coat_pigmentation1.19929588
67MP0003011_delayed_dark_adaptation1.17603648
68MP0003300_gastrointestinal_ulcer1.17009215
69MP0009333_abnormal_splenocyte_physiolog1.16378613
70MP0001958_emphysema1.13903946
71MP0003329_amyloid_beta_deposits1.13850897
72MP0005174_abnormal_tail_pigmentation1.11535602
73MP0003183_abnormal_peptide_metabolism1.09562798
74MP0002295_abnormal_pulmonary_circulatio1.09480818
75MP0008469_abnormal_protein_level1.06753637
76MP0002332_abnormal_exercise_endurance1.03370691
77MP0004185_abnormal_adipocyte_glucose1.01971060
78MP0005390_skeleton_phenotype0.99843976
79MP0003195_calcinosis0.99717867
80MP0002877_abnormal_melanocyte_morpholog0.99545664
81MP0001542_abnormal_bone_strength0.97619295
82MP0005023_abnormal_wound_healing0.97169518
83MP0000716_abnormal_immune_system0.95757154
84MP0000015_abnormal_ear_pigmentation0.95591047
85MP0003091_abnormal_cell_migration0.95436940
86MP0005164_abnormal_response_to0.94382603
87MP0003656_abnormal_erythrocyte_physiolo0.93962980
88MP0003632_abnormal_nervous_system0.93526594
89MP0001853_heart_inflammation0.92123264
90MP0003279_aneurysm0.91400740
91MP0005166_decreased_susceptibility_to0.90245224
92MP0005275_abnormal_skin_tensile0.86768949
93MP0002796_impaired_skin_barrier0.85342017
94MP0009764_decreased_sensitivity_to0.85284671
95MP0005408_hypopigmentation0.81063924
96MP0002098_abnormal_vibrissa_morphology0.80536345
97MP0002277_abnormal_respiratory_mucosa0.78773403
98MP0003705_abnormal_hypodermis_morpholog0.78739016
99MP0001849_ear_inflammation0.78616282
100MP0004883_abnormal_blood_vessel0.76816690
101MP0003566_abnormal_cell_adhesion0.76324517
102MP0005595_abnormal_vascular_smooth0.76166561
103MP0010307_abnormal_tumor_latency0.75746191
104MP0002229_neurodegeneration0.73878108
105MP0002133_abnormal_respiratory_system0.73516098
106MP0005388_respiratory_system_phenotype0.73516098
107MP0002166_altered_tumor_susceptibility0.73443450
108MP0001243_abnormal_dermal_layer0.72162472
109MP0000689_abnormal_spleen_morphology0.71844046
110MP0005647_abnormal_sex_gland0.71600892
111MP0001216_abnormal_epidermal_layer0.71018571
112MP0009765_abnormal_xenobiotic_induced0.70504713
113MP0010155_abnormal_intestine_physiology0.70278847
114MP0002837_dystrophic_cardiac_calcinosis0.70017170
115MP0003795_abnormal_bone_structure0.68932076
116MP0005165_increased_susceptibility_to0.68569657
117MP0005365_abnormal_bile_salt0.67914670
118MP0003828_pulmonary_edema0.67792159
119MP0001663_abnormal_digestive_system0.66970001
120MP0002398_abnormal_bone_marrow0.66479175
121MP0002138_abnormal_hepatobiliary_system0.65772373
122MP0000377_abnormal_hair_follicle0.65321958
123MP0002429_abnormal_blood_cell0.65144064
124MP0000371_diluted_coat_color0.65014195
125MP0002254_reproductive_system_inflammat0.64798732
126MP0009763_increased_sensitivity_to0.64683010
127MP0004134_abnormal_chest_morphology0.64604899
128MP0008874_decreased_physiological_sensi0.62590159
129MP0003186_abnormal_redox_activity0.62484334
130MP0000249_abnormal_blood_vessel0.61707769
131MP0005319_abnormal_enzyme/_coenzyme0.55326822

Predicted human phenotypes

RankGene SetZ-score
1Increased cerebral lipofuscin (HP:0011813)6.37646052
2Increased neuronal autofluorescent lipopigment (HP:0002074)6.03750225
3Recurrent abscess formation (HP:0002722)5.71588551
4Vacuolated lymphocytes (HP:0001922)5.61969627
5Recurrent bacterial skin infections (HP:0005406)5.00439461
6Abnormality of liposaccharide metabolism (HP:0010968)4.74280611
7Abnormality of glycosphingolipid metabolism (HP:0004343)4.74280611
8Abnormality of glycolipid metabolism (HP:0010969)4.74280611
9Parakeratosis (HP:0001036)4.73102701
10Eczematoid dermatitis (HP:0000976)4.70108896
11Abnormality of macrophages (HP:0004311)4.67484349
12Neurofibrillary tangles (HP:0002185)4.55750361
13Axonal loss (HP:0003447)4.41685831
14Loss of speech (HP:0002371)4.20068707
15Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)4.16795844
16Chronic obstructive pulmonary disease (HP:0006510)4.06232111
17Obstructive lung disease (HP:0006536)4.06232111
18Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.98644352
19Dysostosis multiplex (HP:0000943)3.93222226
20Nuclear cataract (HP:0100018)3.89290902
21Recurrent gram-negative bacterial infections (HP:0005420)3.83507379
22Thick nail (HP:0001805)3.80580964
23Hepatosplenomegaly (HP:0001433)3.64918471
24Autoimmune thrombocytopenia (HP:0001973)3.57198946
25Disinhibition (HP:0000734)3.52160544
26Systemic lupus erythematosus (HP:0002725)3.37620717
27Recurrent skin infections (HP:0001581)3.28331382
28Stomatitis (HP:0010280)3.15615606
29Upper motor neuron abnormality (HP:0002127)3.03753197
30Congenital ichthyosiform erythroderma (HP:0007431)3.03181823
31Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.97056816
32Supranuclear gaze palsy (HP:0000605)2.95875376
33Cerebral inclusion bodies (HP:0100314)2.95224842
34Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.92253347
35Degeneration of the lateral corticospinal tracts (HP:0002314)2.92253347
36Inappropriate behavior (HP:0000719)2.82617295
37Segmental peripheral demyelination/remyelination (HP:0003481)2.79693229
38Peripheral hypomyelination (HP:0007182)2.68433341
39Peripheral demyelination (HP:0011096)2.68314771
40Glomerulonephritis (HP:0000099)2.65368040
41J-shaped sella turcica (HP:0002680)2.64487068
42Gingivitis (HP:0000230)2.63807108
43Prostate neoplasm (HP:0100787)2.63455011
44Mucopolysacchariduria (HP:0008155)2.62534406
45Urinary glycosaminoglycan excretion (HP:0003541)2.62534406
46Amyloidosis (HP:0011034)2.61000665
47Metaphyseal irregularity (HP:0003025)2.59248116
48Hematochezia (HP:0002573)2.56524300
49Complement deficiency (HP:0004431)2.56431047
50Sensory axonal neuropathy (HP:0003390)2.48011072
51Mediastinal lymphadenopathy (HP:0100721)2.47682616
52Personality changes (HP:0000751)2.47310458
53Abnormality of polysaccharide metabolism (HP:0011012)2.42974580
54Abnormality of glycosaminoglycan metabolism (HP:0004371)2.42974580
55Abnormality of mucopolysaccharide metabolism (HP:0011020)2.42974580
56Elevated erythrocyte sedimentation rate (HP:0003565)2.41105100
57Onion bulb formation (HP:0003383)2.39899125
58Increased serum ferritin (HP:0003281)2.39504459
59Osteolytic defects of the phalanges of the hand (HP:0009771)2.39471022
60Osteolytic defects of the hand bones (HP:0009699)2.39471022
61Asymmetric septal hypertrophy (HP:0001670)2.32119017
62Erythroderma (HP:0001019)2.31880880
63Clumsiness (HP:0002312)2.29995816
64Apathy (HP:0000741)2.26119361
65Myositis (HP:0100614)2.24726038
66Dementia (HP:0000726)2.23994898
67Diminished motivation (HP:0000745)2.23299704
68Slow saccadic eye movements (HP:0000514)2.19585114
69Abnormality of the lumbar spine (HP:0100712)2.17964425
70Cellulitis (HP:0100658)2.13951707
71Myocardial infarction (HP:0001658)2.12586936
72Retinal atrophy (HP:0001105)2.12551597
73Abolished electroretinogram (ERG) (HP:0000550)2.12505782
74Basal ganglia calcification (HP:0002135)2.11544518
75Chronic otitis media (HP:0000389)2.06474442
76Petechiae (HP:0000967)2.05957792
77Recurrent pneumonia (HP:0006532)2.05604544
78Polyneuropathy (HP:0001271)2.04592813
79Neuronal loss in central nervous system (HP:0002529)2.04162793
80Cardiomegaly (HP:0001640)2.04030970
81Bone pain (HP:0002653)2.02344024
82White forelock (HP:0002211)1.99944444
83Pulmonary infiltrates (HP:0002113)1.98841760
84Interstitial pulmonary disease (HP:0006530)1.98800791
85Vasculitis (HP:0002633)1.98576329
86Patchy hypopigmentation of hair (HP:0011365)1.97523393
87Orchitis (HP:0100796)1.97213797
88Akinesia (HP:0002304)1.96948214
89Pathologic fracture (HP:0002756)1.95945201
90Prolonged neonatal jaundice (HP:0006579)1.95165435
91Urticaria (HP:0001025)1.93586187
92Recurrent fungal infections (HP:0002841)1.93279118
93Nephritis (HP:0000123)1.92129060
94Progressive neurologic deterioration (HP:0002344)1.91792023
95Global brain atrophy (HP:0002283)1.90936915
96Progressive visual loss (HP:0000529)1.90718179
97Keratoconjunctivitis sicca (HP:0001097)1.89534721
98Nausea (HP:0002018)1.88834990
99Abnormality of complement system (HP:0005339)1.85394289
100Anhidrosis (HP:0000970)1.85193411
101Optic neuritis (HP:0100653)1.84810136
102Retrobulbar optic neuritis (HP:0100654)1.84810136
103Agnosia (HP:0010524)1.82902739
104Mutism (HP:0002300)1.81452114
105Hemoptysis (HP:0002105)1.79870558
106Abnormality of iron homeostasis (HP:0011031)1.79007502
107Conjunctival telangiectasia (HP:0000524)1.78764120
108Abnormality of the periventricular white matter (HP:0002518)1.77877948
109Hypoplastic pelvis (HP:0008839)1.77788429
110Meningitis (HP:0001287)1.76001446
111Premature skin wrinkling (HP:0100678)1.75550972
112Increased IgE level (HP:0003212)1.75219153
113Pustule (HP:0200039)1.74723614
114Memory impairment (HP:0002354)1.74529732
115Beaking of vertebral bodies (HP:0004568)1.73394508
116Spondylolisthesis (HP:0003302)1.73125467
117Abnormality of the vasculature of the conjunctiva (HP:0008054)1.72796336
118Purpura (HP:0000979)1.72587576
119Protuberant abdomen (HP:0001538)1.72376390
120Gangrene (HP:0100758)1.72302998
121Spontaneous hematomas (HP:0007420)1.71544936
122Osteomyelitis (HP:0002754)1.70846799
123Leukocytosis (HP:0001974)1.70418096
124Acrocyanosis (HP:0001063)1.69751953
125Abnormality of the corticospinal tract (HP:0002492)1.69032912
126Keratoconjunctivitis (HP:0001096)1.68281758
127Increased CSF protein (HP:0002922)1.67594924
128Thoracic kyphosis (HP:0002942)1.66600044
129Multiple enchondromatosis (HP:0005701)1.65199917
130Abnormality of the basal ganglia (HP:0002134)1.64540761
131Malnutrition (HP:0004395)1.62280732
132Vertebral compression fractures (HP:0002953)1.60928123
133Recurrent lower respiratory tract infections (HP:0002783)1.60703938
134Poor head control (HP:0002421)1.58780117
135Stridor (HP:0010307)1.58124212
136Sepsis (HP:0100806)1.58116746
137Recurrent cutaneous fungal infections (HP:0011370)1.56795810

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK4.17656720
2EPHB14.03145395
3STK393.69135271
4DDR23.25183725
5IRAK43.18537924
6BLK2.97879621
7TAOK22.70865310
8RIPK12.44284227
9OXSR12.42998889
10KIT2.37849041
11MST42.30154856
12RIPK42.26126851
13IRAK32.14505341
14MAP3K112.11272520
15MAP3K142.10988729
16MAPKAPK51.99507347
17NME21.97944913
18TBK11.95036384
19FGR1.90391180
20TAOK11.86722868
21CLK11.83307038
22ERN11.81613971
23PKN11.79948684
24TESK21.78882845
25PIM21.72644732
26CSF1R1.62877358
27MET1.60534517
28IKBKB1.57078879
29MAP2K31.55966810
30CAMKK21.52393440
31TYK21.52365968
32FES1.50793673
33CDC42BPA1.49296391
34ACVR1B1.43501118
35CSK1.41613213
36IKBKE1.40517672
37MAP4K11.36657928
38IRAK21.33041470
39LIMK11.32135244
40TRPM71.26764909
41GRK71.22295258
42ZAP701.19041878
43IRAK11.18816394
44TESK11.18414019
45JAK31.17105948
46TNIK1.14555718
47TAOK31.10162558
48HCK1.08848721
49TGFBR21.06001010
50ABL21.05200280
51MST1R1.02935292
52LYN1.00639568
53LCK1.00339448
54BCR0.98674498
55TGFBR10.98658379
56MAP3K10.96142834
57CHUK0.94489949
58PDGFRA0.92964119
59PAK40.90538382
60TEC0.90502263
61JAK10.90041762
62BMPR1B0.89342366
63CDK190.88782728
64PRKCQ0.87352901
65ITK0.87323471
66BMX0.87190717
67SYK0.84661141
68CDK60.84527576
69WNK10.82906267
70MAP3K50.82454348
71MOS0.81042676
72FGFR20.80685590
73BTK0.80513746
74WNK40.76623250
75BMPR20.76132884
76NEK90.75715883
77ABL10.75425735
78EPHB20.75361139
79TXK0.75254569
80ROCK20.74074459
81MAP3K30.74009424
82STK100.73234817
83CSNK1A1L0.70694952
84MAP2K60.70113092
85LATS20.69721987
86CSNK1G30.69132659
87FYN0.66894511
88TYRO30.64991462
89CSNK1G10.64866220
90RPS6KA50.62088677
91MARK30.62041700
92PRKCD0.61545167
93ICK0.58350103
94GSK3A0.57304501
95JAK20.56312489
96PRPF4B0.54025554
97LRRK20.51529929
98MAP3K130.51464407
99MAPK40.50302482
100CAMK2D0.50301929
101EGFR0.49791347
102RPS6KC10.48612782
103RPS6KL10.48612782
104ADRBK20.48244342
105PRKD10.47981619
106EPHA30.47205843
107ARAF0.46782475
108PDPK10.45500396
109CAMK1G0.45391882
110MAPK150.45017784
111RPS6KA20.44391115
112CAMK1D0.44122879
113MAP2K20.43055941
114MAP3K20.42191892
115TTN0.42134856
116NEK60.42070955
117DMPK0.41555579
118CASK0.41468725
119PRKCE0.40612341
120YES10.40566687
121SIK10.40331195
122MAPK70.39026851
123DAPK20.38745871
124MAPKAPK20.38587383
125PIK3CG0.38510980
126EIF2AK20.38504517
127UHMK10.37450522
128SIK30.37366688
129PDK20.36736204
130RPS6KA60.35427382
131TLK10.35402314
132DAPK30.35099607
133GRK10.34969926
134PDGFRB0.34642522
135MATK0.34449895
136INSR0.34422326
137NUAK10.34085145
138PRKG10.34053183
139PIM10.32391307
140TRIB30.29979112
141STK240.28521624
142DYRK30.28242603
143CAMKK10.24579475
144PRKG20.24544821
145MAP3K80.22589401
146MAP3K60.22489419

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001004.02782153
2Lysosome_Homo sapiens_hsa041423.42239976
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.98792553
4Fatty acid elongation_Homo sapiens_hsa000622.97679649
5Staphylococcus aureus infection_Homo sapiens_hsa051502.68467899
6Glycosaminoglycan degradation_Homo sapiens_hsa005312.46002207
7Other glycan degradation_Homo sapiens_hsa005112.43158793
8Sphingolipid metabolism_Homo sapiens_hsa006002.37956195
9Ether lipid metabolism_Homo sapiens_hsa005652.35515712
10* Phagosome_Homo sapiens_hsa041452.22463574
11Leishmaniasis_Homo sapiens_hsa051402.09259693
12Malaria_Homo sapiens_hsa051442.08155109
13Rheumatoid arthritis_Homo sapiens_hsa053232.07583652
14Pertussis_Homo sapiens_hsa051331.90684955
15Osteoclast differentiation_Homo sapiens_hsa043801.86118307
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.80171413
17Tuberculosis_Homo sapiens_hsa051521.65723440
18Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.63782760
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.58424064
20Type I diabetes mellitus_Homo sapiens_hsa049401.43388134
21B cell receptor signaling pathway_Homo sapiens_hsa046621.37473276
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.31027036
23Collecting duct acid secretion_Homo sapiens_hsa049661.29722871
24* Salmonella infection_Homo sapiens_hsa051321.25899478
25Protein export_Homo sapiens_hsa030601.24983772
26Histidine metabolism_Homo sapiens_hsa003401.24649886
27Graft-versus-host disease_Homo sapiens_hsa053321.23612253
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.22882432
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.21997920
30Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.19223934
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.19068608
32Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.18604274
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.16302868
34Chemokine signaling pathway_Homo sapiens_hsa040621.15027873
35Asthma_Homo sapiens_hsa053101.14696437
36NOD-like receptor signaling pathway_Homo sapiens_hsa046211.12987441
37Sphingolipid signaling pathway_Homo sapiens_hsa040711.11159268
38Shigellosis_Homo sapiens_hsa051311.06569874
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.03590177
40Leukocyte transendothelial migration_Homo sapiens_hsa046701.01993783
41alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01970498
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.01073284
43Arachidonic acid metabolism_Homo sapiens_hsa005901.00263641
44Bladder cancer_Homo sapiens_hsa052191.00161342
45Linoleic acid metabolism_Homo sapiens_hsa005910.99101987
46Hematopoietic cell lineage_Homo sapiens_hsa046400.98727788
47Toxoplasmosis_Homo sapiens_hsa051450.97143958
48Endocytosis_Homo sapiens_hsa041440.94949781
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.94739258
50Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.94297763
51Allograft rejection_Homo sapiens_hsa053300.93370126
52Measles_Homo sapiens_hsa051620.93101063
53Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89384581
54Antigen processing and presentation_Homo sapiens_hsa046120.89023942
55Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.88775121
56Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88584788
57Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.88385058
58Legionellosis_Homo sapiens_hsa051340.85966252
59Mineral absorption_Homo sapiens_hsa049780.85721945
60Intestinal immune network for IgA production_Homo sapiens_hsa046720.84928563
61Acute myeloid leukemia_Homo sapiens_hsa052210.80991879
62Apoptosis_Homo sapiens_hsa042100.80249809
63Vibrio cholerae infection_Homo sapiens_hsa051100.78217645
64Hepatitis C_Homo sapiens_hsa051600.75227765
65Regulation of actin cytoskeleton_Homo sapiens_hsa048100.74615320
66Renal cell carcinoma_Homo sapiens_hsa052110.72992994
67Oxidative phosphorylation_Homo sapiens_hsa001900.72896288
68Autoimmune thyroid disease_Homo sapiens_hsa053200.72893685
69Galactose metabolism_Homo sapiens_hsa000520.68343648
70Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68340754
71Complement and coagulation cascades_Homo sapiens_hsa046100.67621569
72ECM-receptor interaction_Homo sapiens_hsa045120.66167048
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64618934
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.64572064
75Platelet activation_Homo sapiens_hsa046110.64505517
76RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64483636
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.64472864
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61616624
79Axon guidance_Homo sapiens_hsa043600.59235050
80Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.58767488
81Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58435775
82Influenza A_Homo sapiens_hsa051640.58119703
83VEGF signaling pathway_Homo sapiens_hsa043700.55378621
84PPAR signaling pathway_Homo sapiens_hsa033200.54231172
85Viral myocarditis_Homo sapiens_hsa054160.52147916
86TNF signaling pathway_Homo sapiens_hsa046680.51657969
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51487433
88T cell receptor signaling pathway_Homo sapiens_hsa046600.50763780
89Prolactin signaling pathway_Homo sapiens_hsa049170.50288994
90* Amoebiasis_Homo sapiens_hsa051460.49529608
91Epstein-Barr virus infection_Homo sapiens_hsa051690.48854132
92Phospholipase D signaling pathway_Homo sapiens_hsa040720.43377171
93Neurotrophin signaling pathway_Homo sapiens_hsa047220.40907592
94Ras signaling pathway_Homo sapiens_hsa040140.40648279
95Alzheimers disease_Homo sapiens_hsa050100.37912615
96Primary immunodeficiency_Homo sapiens_hsa053400.37658252
97Hepatitis B_Homo sapiens_hsa051610.35833470
98African trypanosomiasis_Homo sapiens_hsa051430.35641410
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.34912012
100Sulfur metabolism_Homo sapiens_hsa009200.34643049
101Pancreatic cancer_Homo sapiens_hsa052120.34347450
102Prion diseases_Homo sapiens_hsa050200.34016621
103Renin-angiotensin system_Homo sapiens_hsa046140.33919892
104Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.33618289
105Glutathione metabolism_Homo sapiens_hsa004800.33319480
106Vitamin B6 metabolism_Homo sapiens_hsa007500.32245530
107Type II diabetes mellitus_Homo sapiens_hsa049300.31165860
108Synaptic vesicle cycle_Homo sapiens_hsa047210.30259078
109Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29135628
110Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.29094391
111HTLV-I infection_Homo sapiens_hsa051660.28312146
112HIF-1 signaling pathway_Homo sapiens_hsa040660.28207532
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.28202778
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27706651
115Fructose and mannose metabolism_Homo sapiens_hsa000510.27529611
116Herpes simplex infection_Homo sapiens_hsa051680.26277733
117Proteoglycans in cancer_Homo sapiens_hsa052050.26043683
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.25648000
119Ovarian steroidogenesis_Homo sapiens_hsa049130.25305285
120Chronic myeloid leukemia_Homo sapiens_hsa052200.22677506
121Notch signaling pathway_Homo sapiens_hsa043300.22042650
122GnRH signaling pathway_Homo sapiens_hsa049120.19452620
123Tryptophan metabolism_Homo sapiens_hsa003800.18278983
124Systemic lupus erythematosus_Homo sapiens_hsa053220.17526537

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