Rank | Gene Set | Z-score |
---|---|---|
1 | central nervous system myelination (GO:0022010) | 5.92787314 |
2 | axon ensheathment in central nervous system (GO:0032291) | 5.92787314 |
3 | modulation by symbiont of host immune response (GO:0052553) | 5.76927787 |
4 | positive regulation by symbiont of host defense response (GO:0052509) | 5.76927787 |
5 | modulation by symbiont of host defense response (GO:0052031) | 5.76927787 |
6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.76927787 |
7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.76927787 |
8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.76927787 |
9 | neutrophil activation involved in immune response (GO:0002283) | 5.60080989 |
10 | negative regulation of interleukin-12 production (GO:0032695) | 5.11975783 |
11 | regulation of vitamin D biosynthetic process (GO:0060556) | 5.04469567 |
12 | oligosaccharide catabolic process (GO:0009313) | 4.77528468 |
13 | fatty acid elongation (GO:0030497) | 4.55813304 |
14 | respiratory burst (GO:0045730) | 4.41117139 |
15 | microglial cell activation (GO:0001774) | 4.38930192 |
16 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.36775183 |
17 | response to lipoprotein particle (GO:0055094) | 4.22173543 |
18 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.18983731 |
19 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.17136237 |
20 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 4.08790306 |
21 | amino sugar catabolic process (GO:0046348) | 4.01414895 |
22 | macrophage activation involved in immune response (GO:0002281) | 3.99926405 |
23 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.99524981 |
24 | regulation of vitamin metabolic process (GO:0030656) | 3.96602503 |
25 | positive regulation of heat generation (GO:0031652) | 3.95537776 |
26 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.93620241 |
27 | amyloid precursor protein metabolic process (GO:0042982) | 3.87813188 |
28 | import into cell (GO:0098657) | 3.81813171 |
29 | regulation of fever generation (GO:0031620) | 3.78870126 |
30 | regulation of podosome assembly (GO:0071801) | 3.78855458 |
31 | response to peptidoglycan (GO:0032494) | 3.75925885 |
32 | regulation of chemokine biosynthetic process (GO:0045073) | 3.75770112 |
33 | pinocytosis (GO:0006907) | 3.75547290 |
34 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.72508836 |
35 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.70899703 |
36 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.70681591 |
37 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.67754200 |
38 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 3.66294775 |
39 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.63128579 |
40 | amyloid precursor protein catabolic process (GO:0042987) | 3.63076864 |
41 | membrane raft organization (GO:0031579) | 3.62780631 |
42 | membrane lipid catabolic process (GO:0046466) | 3.61197726 |
43 | myeloid dendritic cell differentiation (GO:0043011) | 3.59247259 |
44 | myeloid cell activation involved in immune response (GO:0002275) | 3.55687697 |
45 | T-helper 1 type immune response (GO:0042088) | 3.55665809 |
46 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.52889193 |
47 | response to host immune response (GO:0052572) | 3.52889193 |
48 | neutrophil activation (GO:0042119) | 3.52589459 |
49 | ensheathment of neurons (GO:0007272) | 3.52375180 |
50 | axon ensheathment (GO:0008366) | 3.52375180 |
51 | myelination (GO:0042552) | 3.48424177 |
52 | granulocyte activation (GO:0036230) | 3.46432490 |
53 | positive regulation of antigen processing and presentation (GO:0002579) | 3.45720074 |
54 | regulation of cholesterol storage (GO:0010885) | 3.44483813 |
55 | sphingolipid catabolic process (GO:0030149) | 3.43570051 |
56 | NIK/NF-kappaB signaling (GO:0038061) | 3.43163803 |
57 | response to thyroid hormone (GO:0097066) | 3.43076971 |
58 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.40161461 |
59 | L-amino acid import (GO:0043092) | 3.34735454 |
60 | regulation of chronic inflammatory response (GO:0002676) | 3.34608374 |
61 | positive regulation of interferon-alpha production (GO:0032727) | 3.33958666 |
62 | immunoglobulin mediated immune response (GO:0016064) | 3.33800545 |
63 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.33522276 |
64 | intracellular pH reduction (GO:0051452) | 3.28186313 |
65 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.27980824 |
66 | regulation of T cell migration (GO:2000404) | 3.26760795 |
67 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.25218185 |
68 | barbed-end actin filament capping (GO:0051016) | 3.22120657 |
69 | glycosylceramide metabolic process (GO:0006677) | 3.22004129 |
70 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.21333708 |
71 | myeloid dendritic cell activation (GO:0001773) | 3.18488795 |
72 | regulation of interferon-alpha production (GO:0032647) | 3.18399245 |
73 | regulation of macrophage chemotaxis (GO:0010758) | 3.17468929 |
74 | macrophage activation (GO:0042116) | 3.14745655 |
75 | glycosphingolipid catabolic process (GO:0046479) | 3.12999515 |
76 | regulation of antigen processing and presentation (GO:0002577) | 3.12989500 |
77 | adhesion of symbiont to host cell (GO:0044650) | 3.11267756 |
78 | virion attachment to host cell (GO:0019062) | 3.11267756 |
79 | positive regulation of T cell migration (GO:2000406) | 3.08524314 |
80 | regulation of mononuclear cell migration (GO:0071675) | 3.07398095 |
81 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 3.07373602 |
82 | positive regulation of mast cell activation (GO:0033005) | 3.06580931 |
83 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.06141326 |
84 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.05908067 |
85 | N-acetylneuraminate metabolic process (GO:0006054) | 3.05168673 |
86 | regulation of lymphocyte migration (GO:2000401) | 3.04583334 |
87 | regulation of monocyte chemotaxis (GO:0090025) | 3.01538876 |
88 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.01385397 |
89 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.00692976 |
90 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.98670836 |
91 | myelin maintenance (GO:0043217) | 2.97664900 |
92 | regulation of heat generation (GO:0031650) | 2.97042593 |
93 | dendritic cell differentiation (GO:0097028) | 2.96935637 |
94 | pH reduction (GO:0045851) | 2.96761464 |
95 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.94844907 |
96 | response to host (GO:0075136) | 2.94844907 |
97 | response to host defenses (GO:0052200) | 2.94844907 |
98 | cellular response to lipopolysaccharide (GO:0071222) | 2.92951747 |
99 | regulation of collateral sprouting (GO:0048670) | 2.92768821 |
100 | germinal center formation (GO:0002467) | 2.92009569 |
101 | regulation of nitric oxide biosynthetic process (GO:0045428) | 2.91790140 |
102 | low-density lipoprotein particle clearance (GO:0034383) | 2.90642701 |
103 | response to protozoan (GO:0001562) | 2.85874727 |
104 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.85409585 |
105 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 2.83719324 |
106 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.83618556 |
107 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.83592663 |
108 | positive regulation of mast cell degranulation (GO:0043306) | 2.83592663 |
109 | neutrophil mediated immunity (GO:0002446) | 2.83228743 |
110 | superoxide anion generation (GO:0042554) | 2.82973170 |
111 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.82961431 |
112 | cellular response to type I interferon (GO:0071357) | 2.82691367 |
113 | type I interferon signaling pathway (GO:0060337) | 2.82691367 |
114 | cellular response to molecule of bacterial origin (GO:0071219) | 2.81939648 |
115 | negative regulation of lipid storage (GO:0010888) | 2.81792358 |
116 | macrophage differentiation (GO:0030225) | 2.81623806 |
117 | phagosome maturation (GO:0090382) | 2.81216132 |
118 | positive regulation of lymphocyte migration (GO:2000403) | 2.81030379 |
119 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.80560596 |
120 | decidualization (GO:0046697) | 2.79557519 |
121 | glycolipid catabolic process (GO:0019377) | 2.79512706 |
122 | negative regulation of mast cell activation (GO:0033004) | 2.79501707 |
123 | regulation of mast cell activation (GO:0033003) | 2.78752869 |
124 | response to type I interferon (GO:0034340) | 2.78180687 |
125 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.76500143 |
126 | response to muramyl dipeptide (GO:0032495) | 2.75376012 |
127 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 2.75217245 |
128 | ceramide catabolic process (GO:0046514) | 2.74841999 |
129 | detection of molecule of bacterial origin (GO:0032490) | 2.73050532 |
130 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.71780864 |
131 | positive regulation of macrophage cytokine production (GO:0060907) | 2.71664099 |
132 | leukocyte degranulation (GO:0043299) | 2.71645626 |
133 | mast cell activation (GO:0045576) | 2.71288236 |
134 | regulation of leukocyte degranulation (GO:0043300) | 2.71061359 |
135 | cellular response to arsenic-containing substance (GO:0071243) | 2.70593983 |
136 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.69391440 |
137 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.68889459 |
138 | Rap protein signal transduction (GO:0032486) | 2.66708711 |
139 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.66293701 |
140 | defense response to protozoan (GO:0042832) | 2.65489451 |
141 | regulation of interleukin-12 production (GO:0032655) | 2.63969575 |
142 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.63950333 |
143 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.63641374 |
144 | cholesterol biosynthetic process (GO:0006695) | 2.61630359 |
145 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 2.61452485 |
146 | myeloid leukocyte activation (GO:0002274) | 2.60113619 |
147 | regulation of mast cell degranulation (GO:0043304) | 2.59805229 |
148 | protein localization to endosome (GO:0036010) | 2.58314221 |
149 | amino acid import (GO:0043090) | 2.56341026 |
150 | positive regulation of leukocyte degranulation (GO:0043302) | 2.52425997 |
151 | monocyte chemotaxis (GO:0002548) | 2.50240172 |
152 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.50113197 |
153 | regulation of neutrophil migration (GO:1902622) | 2.49447054 |
154 | regulation of neutrophil chemotaxis (GO:0090022) | 2.49447054 |
155 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.49061628 |
156 | leukocyte aggregation (GO:0070486) | 2.48630488 |
157 | lymphocyte chemotaxis (GO:0048247) | 2.48149334 |
158 | adhesion of symbiont to host (GO:0044406) | 2.48143220 |
159 | response to methylmercury (GO:0051597) | 2.46923564 |
160 | negative regulation of interleukin-8 production (GO:0032717) | 2.43258952 |
161 | phagocytosis, engulfment (GO:0006911) | 2.42561607 |
162 | membrane protein ectodomain proteolysis (GO:0006509) | 2.42534964 |
163 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.42453382 |
164 | eosinophil chemotaxis (GO:0048245) | 2.42400495 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 6.18612697 |
2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.47047553 |
3 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 4.18911572 |
4 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.84565164 |
5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.81003656 |
6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.80571413 |
7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.53004591 |
8 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.17596820 |
9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.01067832 |
10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.51439674 |
11 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.44775441 |
12 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.35542610 |
13 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.29109105 |
14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.25500005 |
15 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.25386065 |
16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.23955053 |
17 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.21038563 |
18 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.09608822 |
19 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.01193919 |
20 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.99405425 |
21 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.97611353 |
22 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.90338972 |
23 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.86755431 |
24 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.83590329 |
25 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.81779954 |
26 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.80858695 |
27 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.75017962 |
28 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.72879451 |
29 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.69325850 |
30 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.69293715 |
31 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.68576631 |
32 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.62366421 |
33 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.62366421 |
34 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.61526679 |
35 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.58929172 |
36 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.57612704 |
37 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.57047900 |
38 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.55603135 |
39 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.54757709 |
40 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.51892633 |
41 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.50672691 |
42 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.49864811 |
43 | SPI1_23127762_ChIP-Seq_K562_Human | 1.48328813 |
44 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.48326957 |
45 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.46097902 |
46 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.45576275 |
47 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.44560903 |
48 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.44537888 |
49 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.42911388 |
50 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.42648511 |
51 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.40124490 |
52 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.37572742 |
53 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.37322341 |
54 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.35055599 |
55 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.33231060 |
56 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.33174272 |
57 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31379419 |
58 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.28074899 |
59 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.27458561 |
60 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.25576494 |
61 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.23769668 |
62 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.23288700 |
63 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.21225638 |
64 | MAF_26560356_Chip-Seq_TH1_Human | 1.20528653 |
65 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.20328622 |
66 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.19962807 |
67 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19911955 |
68 | CJUN_26792858_Chip-Seq_BT549_Human | 1.18769395 |
69 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16632453 |
70 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.15595560 |
71 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15580669 |
72 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.14053170 |
73 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.13764042 |
74 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.13405508 |
75 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.13279318 |
76 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.13009767 |
77 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.11401650 |
78 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.11373253 |
79 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.09650186 |
80 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.08657438 |
81 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.07677299 |
82 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.06538469 |
83 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.06440107 |
84 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.06366590 |
85 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04842477 |
86 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.04372364 |
87 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.03434830 |
88 | GATA1_22025678_ChIP-Seq_K562_Human | 1.03073575 |
89 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02083199 |
90 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.01773792 |
91 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01480466 |
92 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00872831 |
93 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.99067071 |
94 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.98753444 |
95 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97889474 |
96 | GATA3_26560356_Chip-Seq_TH2_Human | 0.97203569 |
97 | KDM2B_26808549_Chip-Seq_K562_Human | 0.96950764 |
98 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96820853 |
99 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.96660957 |
100 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.96580114 |
101 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.96402566 |
102 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.95778767 |
103 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.95236898 |
104 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.95086464 |
105 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.93989464 |
106 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93064731 |
107 | MYB_26560356_Chip-Seq_TH2_Human | 0.92733557 |
108 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.92498337 |
109 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.91381804 |
110 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.90505196 |
111 | UTX_26944678_Chip-Seq_JUKART_Human | 0.90224962 |
112 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.88979231 |
113 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.87206321 |
114 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.87165916 |
115 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.86686514 |
116 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.85940772 |
117 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.85874375 |
118 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.85754436 |
119 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85650289 |
120 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.85463325 |
121 | MAF_26560356_Chip-Seq_TH2_Human | 0.84890851 |
122 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.80738543 |
123 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.79914946 |
124 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.78949791 |
125 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.77789112 |
126 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.76897486 |
127 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.75372175 |
128 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.75372175 |
129 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.72379152 |
130 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.72242744 |
131 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.71269186 |
132 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.70394790 |
133 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.69216528 |
134 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.67836230 |
135 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.67082717 |
136 | TP53_16413492_ChIP-PET_HCT116_Human | 0.66584480 |
137 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.65788682 |
138 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.65746184 |
139 | GATA2_19941826_ChIP-Seq_K562_Human | 0.63859343 |
140 | GATA1_19941826_ChIP-Seq_K562_Human | 0.63821554 |
141 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.63275394 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005058_abnormal_lysosome_morphology | 4.33713721 |
2 | MP0000920_abnormal_myelination | 3.76673443 |
3 | MP0001835_abnormal_antigen_presentation | 3.72118668 |
4 | MP0006082_CNS_inflammation | 3.50149271 |
5 | MP0003690_abnormal_glial_cell | 3.38005473 |
6 | MP0003303_peritoneal_inflammation | 3.13348886 |
7 | MP0003436_decreased_susceptibility_to | 2.88078163 |
8 | MP0002419_abnormal_innate_immunity | 2.85242244 |
9 | MP0002148_abnormal_hypersensitivity_rea | 2.82192369 |
10 | MP0002139_abnormal_hepatobiliary_system | 2.80470584 |
11 | MP0005000_abnormal_immune_tolerance | 2.58880628 |
12 | MP0003136_yellow_coat_color | 2.44165620 |
13 | MP0003950_abnormal_plasma_membrane | 2.37748181 |
14 | MP0003172_abnormal_lysosome_physiology | 2.35296645 |
15 | MP0004381_abnormal_hair_follicle | 2.23513482 |
16 | MP0000604_amyloidosis | 2.23138691 |
17 | MP0005025_abnormal_response_to | 2.22834803 |
18 | MP0009785_altered_susceptibility_to | 2.19988070 |
19 | MP0008438_abnormal_cutaneous_collagen | 2.11002013 |
20 | MP0000383_abnormal_hair_follicle | 2.10081603 |
21 | MP0001790_abnormal_immune_system | 2.08746538 |
22 | MP0005387_immune_system_phenotype | 2.08746538 |
23 | MP0003724_increased_susceptibility_to | 2.08181904 |
24 | MP0002452_abnormal_antigen_presenting | 2.04234699 |
25 | MP0001851_eye_inflammation | 1.99116328 |
26 | MP0009278_abnormal_bone_marrow | 1.93828448 |
27 | MP0001533_abnormal_skeleton_physiology | 1.88232259 |
28 | MP0002723_abnormal_immune_serum | 1.83224221 |
29 | MP0010678_abnormal_skin_adnexa | 1.76463441 |
30 | MP0006054_spinal_hemorrhage | 1.75229104 |
31 | MP0008004_abnormal_stomach_pH | 1.74256699 |
32 | MP0005397_hematopoietic_system_phenotyp | 1.70287718 |
33 | MP0001545_abnormal_hematopoietic_system | 1.70287718 |
34 | MP0001800_abnormal_humoral_immune | 1.67766540 |
35 | MP0005257_abnormal_intraocular_pressure | 1.66280360 |
36 | MP0001819_abnormal_immune_cell | 1.65421297 |
37 | MP0005171_absent_coat_pigmentation | 1.65215666 |
38 | MP0002420_abnormal_adaptive_immunity | 1.63296859 |
39 | MP0005409_darkened_coat_color | 1.62995445 |
40 | MP0005451_abnormal_body_composition | 1.62450841 |
41 | MP0005167_abnormal_blood-brain_barrier | 1.60771724 |
42 | MP0005671_abnormal_response_to | 1.59517929 |
43 | MP0003634_abnormal_glial_cell | 1.59130479 |
44 | MP0009840_abnormal_foam_cell | 1.56541443 |
45 | MP0003806_abnormal_nucleotide_metabolis | 1.56425263 |
46 | MP0003075_altered_response_to | 1.52821334 |
47 | MP0000685_abnormal_immune_system | 1.52257673 |
48 | MP0003448_altered_tumor_morphology | 1.51668544 |
49 | MP0000343_altered_response_to | 1.50422865 |
50 | MP0004510_myositis | 1.48644502 |
51 | MP0000858_altered_metastatic_potential | 1.46087791 |
52 | MP0005464_abnormal_platelet_physiology | 1.45921923 |
53 | MP0005310_abnormal_salivary_gland | 1.40803274 |
54 | MP0002998_abnormal_bone_remodeling | 1.40208960 |
55 | MP0000465_gastrointestinal_hemorrhage | 1.38589573 |
56 | MP0004947_skin_inflammation | 1.32966156 |
57 | MP0002090_abnormal_vision | 1.31264716 |
58 | MP0002933_joint_inflammation | 1.29522519 |
59 | MP0000647_abnormal_sebaceous_gland | 1.28290684 |
60 | MP0002405_respiratory_system_inflammati | 1.26804790 |
61 | MP0008260_abnormal_autophagy | 1.24236599 |
62 | MP0003191_abnormal_cellular_cholesterol | 1.23412857 |
63 | MP0003453_abnormal_keratinocyte_physiol | 1.21699676 |
64 | MP0004742_abnormal_vestibular_system | 1.21411029 |
65 | MP0001845_abnormal_inflammatory_respons | 1.20031385 |
66 | MP0000372_irregular_coat_pigmentation | 1.19929588 |
67 | MP0003011_delayed_dark_adaptation | 1.17603648 |
68 | MP0003300_gastrointestinal_ulcer | 1.17009215 |
69 | MP0009333_abnormal_splenocyte_physiolog | 1.16378613 |
70 | MP0001958_emphysema | 1.13903946 |
71 | MP0003329_amyloid_beta_deposits | 1.13850897 |
72 | MP0005174_abnormal_tail_pigmentation | 1.11535602 |
73 | MP0003183_abnormal_peptide_metabolism | 1.09562798 |
74 | MP0002295_abnormal_pulmonary_circulatio | 1.09480818 |
75 | MP0008469_abnormal_protein_level | 1.06753637 |
76 | MP0002332_abnormal_exercise_endurance | 1.03370691 |
77 | MP0004185_abnormal_adipocyte_glucose | 1.01971060 |
78 | MP0005390_skeleton_phenotype | 0.99843976 |
79 | MP0003195_calcinosis | 0.99717867 |
80 | MP0002877_abnormal_melanocyte_morpholog | 0.99545664 |
81 | MP0001542_abnormal_bone_strength | 0.97619295 |
82 | MP0005023_abnormal_wound_healing | 0.97169518 |
83 | MP0000716_abnormal_immune_system | 0.95757154 |
84 | MP0000015_abnormal_ear_pigmentation | 0.95591047 |
85 | MP0003091_abnormal_cell_migration | 0.95436940 |
86 | MP0005164_abnormal_response_to | 0.94382603 |
87 | MP0003656_abnormal_erythrocyte_physiolo | 0.93962980 |
88 | MP0003632_abnormal_nervous_system | 0.93526594 |
89 | MP0001853_heart_inflammation | 0.92123264 |
90 | MP0003279_aneurysm | 0.91400740 |
91 | MP0005166_decreased_susceptibility_to | 0.90245224 |
92 | MP0005275_abnormal_skin_tensile | 0.86768949 |
93 | MP0002796_impaired_skin_barrier | 0.85342017 |
94 | MP0009764_decreased_sensitivity_to | 0.85284671 |
95 | MP0005408_hypopigmentation | 0.81063924 |
96 | MP0002098_abnormal_vibrissa_morphology | 0.80536345 |
97 | MP0002277_abnormal_respiratory_mucosa | 0.78773403 |
98 | MP0003705_abnormal_hypodermis_morpholog | 0.78739016 |
99 | MP0001849_ear_inflammation | 0.78616282 |
100 | MP0004883_abnormal_blood_vessel | 0.76816690 |
101 | MP0003566_abnormal_cell_adhesion | 0.76324517 |
102 | MP0005595_abnormal_vascular_smooth | 0.76166561 |
103 | MP0010307_abnormal_tumor_latency | 0.75746191 |
104 | MP0002229_neurodegeneration | 0.73878108 |
105 | MP0002133_abnormal_respiratory_system | 0.73516098 |
106 | MP0005388_respiratory_system_phenotype | 0.73516098 |
107 | MP0002166_altered_tumor_susceptibility | 0.73443450 |
108 | MP0001243_abnormal_dermal_layer | 0.72162472 |
109 | MP0000689_abnormal_spleen_morphology | 0.71844046 |
110 | MP0005647_abnormal_sex_gland | 0.71600892 |
111 | MP0001216_abnormal_epidermal_layer | 0.71018571 |
112 | MP0009765_abnormal_xenobiotic_induced | 0.70504713 |
113 | MP0010155_abnormal_intestine_physiology | 0.70278847 |
114 | MP0002837_dystrophic_cardiac_calcinosis | 0.70017170 |
115 | MP0003795_abnormal_bone_structure | 0.68932076 |
116 | MP0005165_increased_susceptibility_to | 0.68569657 |
117 | MP0005365_abnormal_bile_salt | 0.67914670 |
118 | MP0003828_pulmonary_edema | 0.67792159 |
119 | MP0001663_abnormal_digestive_system | 0.66970001 |
120 | MP0002398_abnormal_bone_marrow | 0.66479175 |
121 | MP0002138_abnormal_hepatobiliary_system | 0.65772373 |
122 | MP0000377_abnormal_hair_follicle | 0.65321958 |
123 | MP0002429_abnormal_blood_cell | 0.65144064 |
124 | MP0000371_diluted_coat_color | 0.65014195 |
125 | MP0002254_reproductive_system_inflammat | 0.64798732 |
126 | MP0009763_increased_sensitivity_to | 0.64683010 |
127 | MP0004134_abnormal_chest_morphology | 0.64604899 |
128 | MP0008874_decreased_physiological_sensi | 0.62590159 |
129 | MP0003186_abnormal_redox_activity | 0.62484334 |
130 | MP0000249_abnormal_blood_vessel | 0.61707769 |
131 | MP0005319_abnormal_enzyme/_coenzyme | 0.55326822 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased cerebral lipofuscin (HP:0011813) | 6.37646052 |
2 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 6.03750225 |
3 | Recurrent abscess formation (HP:0002722) | 5.71588551 |
4 | Vacuolated lymphocytes (HP:0001922) | 5.61969627 |
5 | Recurrent bacterial skin infections (HP:0005406) | 5.00439461 |
6 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.74280611 |
7 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.74280611 |
8 | Abnormality of glycolipid metabolism (HP:0010969) | 4.74280611 |
9 | Parakeratosis (HP:0001036) | 4.73102701 |
10 | Eczematoid dermatitis (HP:0000976) | 4.70108896 |
11 | Abnormality of macrophages (HP:0004311) | 4.67484349 |
12 | Neurofibrillary tangles (HP:0002185) | 4.55750361 |
13 | Axonal loss (HP:0003447) | 4.41685831 |
14 | Loss of speech (HP:0002371) | 4.20068707 |
15 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 4.16795844 |
16 | Chronic obstructive pulmonary disease (HP:0006510) | 4.06232111 |
17 | Obstructive lung disease (HP:0006536) | 4.06232111 |
18 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.98644352 |
19 | Dysostosis multiplex (HP:0000943) | 3.93222226 |
20 | Nuclear cataract (HP:0100018) | 3.89290902 |
21 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.83507379 |
22 | Thick nail (HP:0001805) | 3.80580964 |
23 | Hepatosplenomegaly (HP:0001433) | 3.64918471 |
24 | Autoimmune thrombocytopenia (HP:0001973) | 3.57198946 |
25 | Disinhibition (HP:0000734) | 3.52160544 |
26 | Systemic lupus erythematosus (HP:0002725) | 3.37620717 |
27 | Recurrent skin infections (HP:0001581) | 3.28331382 |
28 | Stomatitis (HP:0010280) | 3.15615606 |
29 | Upper motor neuron abnormality (HP:0002127) | 3.03753197 |
30 | Congenital ichthyosiform erythroderma (HP:0007431) | 3.03181823 |
31 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.97056816 |
32 | Supranuclear gaze palsy (HP:0000605) | 2.95875376 |
33 | Cerebral inclusion bodies (HP:0100314) | 2.95224842 |
34 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.92253347 |
35 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.92253347 |
36 | Inappropriate behavior (HP:0000719) | 2.82617295 |
37 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.79693229 |
38 | Peripheral hypomyelination (HP:0007182) | 2.68433341 |
39 | Peripheral demyelination (HP:0011096) | 2.68314771 |
40 | Glomerulonephritis (HP:0000099) | 2.65368040 |
41 | J-shaped sella turcica (HP:0002680) | 2.64487068 |
42 | Gingivitis (HP:0000230) | 2.63807108 |
43 | Prostate neoplasm (HP:0100787) | 2.63455011 |
44 | Mucopolysacchariduria (HP:0008155) | 2.62534406 |
45 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.62534406 |
46 | Amyloidosis (HP:0011034) | 2.61000665 |
47 | Metaphyseal irregularity (HP:0003025) | 2.59248116 |
48 | Hematochezia (HP:0002573) | 2.56524300 |
49 | Complement deficiency (HP:0004431) | 2.56431047 |
50 | Sensory axonal neuropathy (HP:0003390) | 2.48011072 |
51 | Mediastinal lymphadenopathy (HP:0100721) | 2.47682616 |
52 | Personality changes (HP:0000751) | 2.47310458 |
53 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.42974580 |
54 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.42974580 |
55 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.42974580 |
56 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.41105100 |
57 | Onion bulb formation (HP:0003383) | 2.39899125 |
58 | Increased serum ferritin (HP:0003281) | 2.39504459 |
59 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.39471022 |
60 | Osteolytic defects of the hand bones (HP:0009699) | 2.39471022 |
61 | Asymmetric septal hypertrophy (HP:0001670) | 2.32119017 |
62 | Erythroderma (HP:0001019) | 2.31880880 |
63 | Clumsiness (HP:0002312) | 2.29995816 |
64 | Apathy (HP:0000741) | 2.26119361 |
65 | Myositis (HP:0100614) | 2.24726038 |
66 | Dementia (HP:0000726) | 2.23994898 |
67 | Diminished motivation (HP:0000745) | 2.23299704 |
68 | Slow saccadic eye movements (HP:0000514) | 2.19585114 |
69 | Abnormality of the lumbar spine (HP:0100712) | 2.17964425 |
70 | Cellulitis (HP:0100658) | 2.13951707 |
71 | Myocardial infarction (HP:0001658) | 2.12586936 |
72 | Retinal atrophy (HP:0001105) | 2.12551597 |
73 | Abolished electroretinogram (ERG) (HP:0000550) | 2.12505782 |
74 | Basal ganglia calcification (HP:0002135) | 2.11544518 |
75 | Chronic otitis media (HP:0000389) | 2.06474442 |
76 | Petechiae (HP:0000967) | 2.05957792 |
77 | Recurrent pneumonia (HP:0006532) | 2.05604544 |
78 | Polyneuropathy (HP:0001271) | 2.04592813 |
79 | Neuronal loss in central nervous system (HP:0002529) | 2.04162793 |
80 | Cardiomegaly (HP:0001640) | 2.04030970 |
81 | Bone pain (HP:0002653) | 2.02344024 |
82 | White forelock (HP:0002211) | 1.99944444 |
83 | Pulmonary infiltrates (HP:0002113) | 1.98841760 |
84 | Interstitial pulmonary disease (HP:0006530) | 1.98800791 |
85 | Vasculitis (HP:0002633) | 1.98576329 |
86 | Patchy hypopigmentation of hair (HP:0011365) | 1.97523393 |
87 | Orchitis (HP:0100796) | 1.97213797 |
88 | Akinesia (HP:0002304) | 1.96948214 |
89 | Pathologic fracture (HP:0002756) | 1.95945201 |
90 | Prolonged neonatal jaundice (HP:0006579) | 1.95165435 |
91 | Urticaria (HP:0001025) | 1.93586187 |
92 | Recurrent fungal infections (HP:0002841) | 1.93279118 |
93 | Nephritis (HP:0000123) | 1.92129060 |
94 | Progressive neurologic deterioration (HP:0002344) | 1.91792023 |
95 | Global brain atrophy (HP:0002283) | 1.90936915 |
96 | Progressive visual loss (HP:0000529) | 1.90718179 |
97 | Keratoconjunctivitis sicca (HP:0001097) | 1.89534721 |
98 | Nausea (HP:0002018) | 1.88834990 |
99 | Abnormality of complement system (HP:0005339) | 1.85394289 |
100 | Anhidrosis (HP:0000970) | 1.85193411 |
101 | Optic neuritis (HP:0100653) | 1.84810136 |
102 | Retrobulbar optic neuritis (HP:0100654) | 1.84810136 |
103 | Agnosia (HP:0010524) | 1.82902739 |
104 | Mutism (HP:0002300) | 1.81452114 |
105 | Hemoptysis (HP:0002105) | 1.79870558 |
106 | Abnormality of iron homeostasis (HP:0011031) | 1.79007502 |
107 | Conjunctival telangiectasia (HP:0000524) | 1.78764120 |
108 | Abnormality of the periventricular white matter (HP:0002518) | 1.77877948 |
109 | Hypoplastic pelvis (HP:0008839) | 1.77788429 |
110 | Meningitis (HP:0001287) | 1.76001446 |
111 | Premature skin wrinkling (HP:0100678) | 1.75550972 |
112 | Increased IgE level (HP:0003212) | 1.75219153 |
113 | Pustule (HP:0200039) | 1.74723614 |
114 | Memory impairment (HP:0002354) | 1.74529732 |
115 | Beaking of vertebral bodies (HP:0004568) | 1.73394508 |
116 | Spondylolisthesis (HP:0003302) | 1.73125467 |
117 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.72796336 |
118 | Purpura (HP:0000979) | 1.72587576 |
119 | Protuberant abdomen (HP:0001538) | 1.72376390 |
120 | Gangrene (HP:0100758) | 1.72302998 |
121 | Spontaneous hematomas (HP:0007420) | 1.71544936 |
122 | Osteomyelitis (HP:0002754) | 1.70846799 |
123 | Leukocytosis (HP:0001974) | 1.70418096 |
124 | Acrocyanosis (HP:0001063) | 1.69751953 |
125 | Abnormality of the corticospinal tract (HP:0002492) | 1.69032912 |
126 | Keratoconjunctivitis (HP:0001096) | 1.68281758 |
127 | Increased CSF protein (HP:0002922) | 1.67594924 |
128 | Thoracic kyphosis (HP:0002942) | 1.66600044 |
129 | Multiple enchondromatosis (HP:0005701) | 1.65199917 |
130 | Abnormality of the basal ganglia (HP:0002134) | 1.64540761 |
131 | Malnutrition (HP:0004395) | 1.62280732 |
132 | Vertebral compression fractures (HP:0002953) | 1.60928123 |
133 | Recurrent lower respiratory tract infections (HP:0002783) | 1.60703938 |
134 | Poor head control (HP:0002421) | 1.58780117 |
135 | Stridor (HP:0010307) | 1.58124212 |
136 | Sepsis (HP:0100806) | 1.58116746 |
137 | Recurrent cutaneous fungal infections (HP:0011370) | 1.56795810 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PBK | 4.17656720 |
2 | EPHB1 | 4.03145395 |
3 | STK39 | 3.69135271 |
4 | DDR2 | 3.25183725 |
5 | IRAK4 | 3.18537924 |
6 | BLK | 2.97879621 |
7 | TAOK2 | 2.70865310 |
8 | RIPK1 | 2.44284227 |
9 | OXSR1 | 2.42998889 |
10 | KIT | 2.37849041 |
11 | MST4 | 2.30154856 |
12 | RIPK4 | 2.26126851 |
13 | IRAK3 | 2.14505341 |
14 | MAP3K11 | 2.11272520 |
15 | MAP3K14 | 2.10988729 |
16 | MAPKAPK5 | 1.99507347 |
17 | NME2 | 1.97944913 |
18 | TBK1 | 1.95036384 |
19 | FGR | 1.90391180 |
20 | TAOK1 | 1.86722868 |
21 | CLK1 | 1.83307038 |
22 | ERN1 | 1.81613971 |
23 | PKN1 | 1.79948684 |
24 | TESK2 | 1.78882845 |
25 | PIM2 | 1.72644732 |
26 | CSF1R | 1.62877358 |
27 | MET | 1.60534517 |
28 | IKBKB | 1.57078879 |
29 | MAP2K3 | 1.55966810 |
30 | CAMKK2 | 1.52393440 |
31 | TYK2 | 1.52365968 |
32 | FES | 1.50793673 |
33 | CDC42BPA | 1.49296391 |
34 | ACVR1B | 1.43501118 |
35 | CSK | 1.41613213 |
36 | IKBKE | 1.40517672 |
37 | MAP4K1 | 1.36657928 |
38 | IRAK2 | 1.33041470 |
39 | LIMK1 | 1.32135244 |
40 | TRPM7 | 1.26764909 |
41 | GRK7 | 1.22295258 |
42 | ZAP70 | 1.19041878 |
43 | IRAK1 | 1.18816394 |
44 | TESK1 | 1.18414019 |
45 | JAK3 | 1.17105948 |
46 | TNIK | 1.14555718 |
47 | TAOK3 | 1.10162558 |
48 | HCK | 1.08848721 |
49 | TGFBR2 | 1.06001010 |
50 | ABL2 | 1.05200280 |
51 | MST1R | 1.02935292 |
52 | LYN | 1.00639568 |
53 | LCK | 1.00339448 |
54 | BCR | 0.98674498 |
55 | TGFBR1 | 0.98658379 |
56 | MAP3K1 | 0.96142834 |
57 | CHUK | 0.94489949 |
58 | PDGFRA | 0.92964119 |
59 | PAK4 | 0.90538382 |
60 | TEC | 0.90502263 |
61 | JAK1 | 0.90041762 |
62 | BMPR1B | 0.89342366 |
63 | CDK19 | 0.88782728 |
64 | PRKCQ | 0.87352901 |
65 | ITK | 0.87323471 |
66 | BMX | 0.87190717 |
67 | SYK | 0.84661141 |
68 | CDK6 | 0.84527576 |
69 | WNK1 | 0.82906267 |
70 | MAP3K5 | 0.82454348 |
71 | MOS | 0.81042676 |
72 | FGFR2 | 0.80685590 |
73 | BTK | 0.80513746 |
74 | WNK4 | 0.76623250 |
75 | BMPR2 | 0.76132884 |
76 | NEK9 | 0.75715883 |
77 | ABL1 | 0.75425735 |
78 | EPHB2 | 0.75361139 |
79 | TXK | 0.75254569 |
80 | ROCK2 | 0.74074459 |
81 | MAP3K3 | 0.74009424 |
82 | STK10 | 0.73234817 |
83 | CSNK1A1L | 0.70694952 |
84 | MAP2K6 | 0.70113092 |
85 | LATS2 | 0.69721987 |
86 | CSNK1G3 | 0.69132659 |
87 | FYN | 0.66894511 |
88 | TYRO3 | 0.64991462 |
89 | CSNK1G1 | 0.64866220 |
90 | RPS6KA5 | 0.62088677 |
91 | MARK3 | 0.62041700 |
92 | PRKCD | 0.61545167 |
93 | ICK | 0.58350103 |
94 | GSK3A | 0.57304501 |
95 | JAK2 | 0.56312489 |
96 | PRPF4B | 0.54025554 |
97 | LRRK2 | 0.51529929 |
98 | MAP3K13 | 0.51464407 |
99 | MAPK4 | 0.50302482 |
100 | CAMK2D | 0.50301929 |
101 | EGFR | 0.49791347 |
102 | RPS6KC1 | 0.48612782 |
103 | RPS6KL1 | 0.48612782 |
104 | ADRBK2 | 0.48244342 |
105 | PRKD1 | 0.47981619 |
106 | EPHA3 | 0.47205843 |
107 | ARAF | 0.46782475 |
108 | PDPK1 | 0.45500396 |
109 | CAMK1G | 0.45391882 |
110 | MAPK15 | 0.45017784 |
111 | RPS6KA2 | 0.44391115 |
112 | CAMK1D | 0.44122879 |
113 | MAP2K2 | 0.43055941 |
114 | MAP3K2 | 0.42191892 |
115 | TTN | 0.42134856 |
116 | NEK6 | 0.42070955 |
117 | DMPK | 0.41555579 |
118 | CASK | 0.41468725 |
119 | PRKCE | 0.40612341 |
120 | YES1 | 0.40566687 |
121 | SIK1 | 0.40331195 |
122 | MAPK7 | 0.39026851 |
123 | DAPK2 | 0.38745871 |
124 | MAPKAPK2 | 0.38587383 |
125 | PIK3CG | 0.38510980 |
126 | EIF2AK2 | 0.38504517 |
127 | UHMK1 | 0.37450522 |
128 | SIK3 | 0.37366688 |
129 | PDK2 | 0.36736204 |
130 | RPS6KA6 | 0.35427382 |
131 | TLK1 | 0.35402314 |
132 | DAPK3 | 0.35099607 |
133 | GRK1 | 0.34969926 |
134 | PDGFRB | 0.34642522 |
135 | MATK | 0.34449895 |
136 | INSR | 0.34422326 |
137 | NUAK1 | 0.34085145 |
138 | PRKG1 | 0.34053183 |
139 | PIM1 | 0.32391307 |
140 | TRIB3 | 0.29979112 |
141 | STK24 | 0.28521624 |
142 | DYRK3 | 0.28242603 |
143 | CAMKK1 | 0.24579475 |
144 | PRKG2 | 0.24544821 |
145 | MAP3K8 | 0.22589401 |
146 | MAP3K6 | 0.22489419 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Steroid biosynthesis_Homo sapiens_hsa00100 | 4.02782153 |
2 | Lysosome_Homo sapiens_hsa04142 | 3.42239976 |
3 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.98792553 |
4 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.97679649 |
5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.68467899 |
6 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.46002207 |
7 | Other glycan degradation_Homo sapiens_hsa00511 | 2.43158793 |
8 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.37956195 |
9 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.35515712 |
10 | * Phagosome_Homo sapiens_hsa04145 | 2.22463574 |
11 | Leishmaniasis_Homo sapiens_hsa05140 | 2.09259693 |
12 | Malaria_Homo sapiens_hsa05144 | 2.08155109 |
13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.07583652 |
14 | Pertussis_Homo sapiens_hsa05133 | 1.90684955 |
15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.86118307 |
16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.80171413 |
17 | Tuberculosis_Homo sapiens_hsa05152 | 1.65723440 |
18 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.63782760 |
19 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.58424064 |
20 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.43388134 |
21 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.37473276 |
22 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.31027036 |
23 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.29722871 |
24 | * Salmonella infection_Homo sapiens_hsa05132 | 1.25899478 |
25 | Protein export_Homo sapiens_hsa03060 | 1.24983772 |
26 | Histidine metabolism_Homo sapiens_hsa00340 | 1.24649886 |
27 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.23612253 |
28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.22882432 |
29 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.21997920 |
30 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.19223934 |
31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.19068608 |
32 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.18604274 |
33 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.16302868 |
34 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.15027873 |
35 | Asthma_Homo sapiens_hsa05310 | 1.14696437 |
36 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.12987441 |
37 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 1.11159268 |
38 | Shigellosis_Homo sapiens_hsa05131 | 1.06569874 |
39 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.03590177 |
40 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.01993783 |
41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.01970498 |
42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.01073284 |
43 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.00263641 |
44 | Bladder cancer_Homo sapiens_hsa05219 | 1.00161342 |
45 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.99101987 |
46 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.98727788 |
47 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.97143958 |
48 | Endocytosis_Homo sapiens_hsa04144 | 0.94949781 |
49 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.94739258 |
50 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.94297763 |
51 | Allograft rejection_Homo sapiens_hsa05330 | 0.93370126 |
52 | Measles_Homo sapiens_hsa05162 | 0.93101063 |
53 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.89384581 |
54 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.89023942 |
55 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.88775121 |
56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.88584788 |
57 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.88385058 |
58 | Legionellosis_Homo sapiens_hsa05134 | 0.85966252 |
59 | Mineral absorption_Homo sapiens_hsa04978 | 0.85721945 |
60 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.84928563 |
61 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.80991879 |
62 | Apoptosis_Homo sapiens_hsa04210 | 0.80249809 |
63 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.78217645 |
64 | Hepatitis C_Homo sapiens_hsa05160 | 0.75227765 |
65 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.74615320 |
66 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.72992994 |
67 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.72896288 |
68 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.72893685 |
69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.68343648 |
70 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.68340754 |
71 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.67621569 |
72 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.66167048 |
73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.64618934 |
74 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.64572064 |
75 | Platelet activation_Homo sapiens_hsa04611 | 0.64505517 |
76 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.64483636 |
77 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.64472864 |
78 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.61616624 |
79 | Axon guidance_Homo sapiens_hsa04360 | 0.59235050 |
80 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.58767488 |
81 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.58435775 |
82 | Influenza A_Homo sapiens_hsa05164 | 0.58119703 |
83 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55378621 |
84 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.54231172 |
85 | Viral myocarditis_Homo sapiens_hsa05416 | 0.52147916 |
86 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.51657969 |
87 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.51487433 |
88 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.50763780 |
89 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.50288994 |
90 | * Amoebiasis_Homo sapiens_hsa05146 | 0.49529608 |
91 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48854132 |
92 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43377171 |
93 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.40907592 |
94 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.40648279 |
95 | Alzheimers disease_Homo sapiens_hsa05010 | 0.37912615 |
96 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.37658252 |
97 | Hepatitis B_Homo sapiens_hsa05161 | 0.35833470 |
98 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.35641410 |
99 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34912012 |
100 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.34643049 |
101 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.34347450 |
102 | Prion diseases_Homo sapiens_hsa05020 | 0.34016621 |
103 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.33919892 |
104 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.33618289 |
105 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.33319480 |
106 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.32245530 |
107 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.31165860 |
108 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.30259078 |
109 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.29135628 |
110 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.29094391 |
111 | HTLV-I infection_Homo sapiens_hsa05166 | 0.28312146 |
112 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.28207532 |
113 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.28202778 |
114 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.27706651 |
115 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.27529611 |
116 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.26277733 |
117 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.26043683 |
118 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.25648000 |
119 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25305285 |
120 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.22677506 |
121 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.22042650 |
122 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.19452620 |
123 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.18278983 |
124 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.17526537 |