Rank | Gene Set | Z-score |
---|---|---|
1 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.72941511 |
2 | neuron cell-cell adhesion (GO:0007158) | 5.41428536 |
3 | vocalization behavior (GO:0071625) | 5.37633377 |
4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.37264546 |
5 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.91409529 |
6 | synaptic vesicle exocytosis (GO:0016079) | 4.76547461 |
7 | nucleobase catabolic process (GO:0046113) | 4.70088743 |
8 | protein localization to synapse (GO:0035418) | 4.69448106 |
9 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.60990772 |
10 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.60806872 |
11 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.59345282 |
12 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.57084739 |
13 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.44904764 |
14 | synaptic vesicle maturation (GO:0016188) | 4.35531115 |
15 | glutamate secretion (GO:0014047) | 4.30149572 |
16 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.27346613 |
17 | locomotory exploration behavior (GO:0035641) | 4.19319720 |
18 | glutamate receptor signaling pathway (GO:0007215) | 4.12192919 |
19 | regulation of synaptic vesicle transport (GO:1902803) | 4.08805660 |
20 | presynaptic membrane assembly (GO:0097105) | 4.07739470 |
21 | neuron recognition (GO:0008038) | 4.06746729 |
22 | neurotransmitter secretion (GO:0007269) | 4.03255486 |
23 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.01238094 |
24 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.99270787 |
25 | exploration behavior (GO:0035640) | 3.96707215 |
26 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.94070201 |
27 | postsynaptic membrane organization (GO:0001941) | 3.90512546 |
28 | establishment of mitochondrion localization (GO:0051654) | 3.89592113 |
29 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.86152842 |
30 | synaptic transmission, glutamatergic (GO:0035249) | 3.83642581 |
31 | presynaptic membrane organization (GO:0097090) | 3.83616634 |
32 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.83579933 |
33 | neuron-neuron synaptic transmission (GO:0007270) | 3.82465648 |
34 | neuronal action potential propagation (GO:0019227) | 3.77838191 |
35 | proline transport (GO:0015824) | 3.77001218 |
36 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.75431831 |
37 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.74426607 |
38 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.72026995 |
39 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.69060703 |
40 | transmission of nerve impulse (GO:0019226) | 3.64626116 |
41 | axonal fasciculation (GO:0007413) | 3.62456781 |
42 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.58691923 |
43 | neurotransmitter transport (GO:0006836) | 3.57339491 |
44 | synaptic vesicle endocytosis (GO:0048488) | 3.54566377 |
45 | gamma-aminobutyric acid transport (GO:0015812) | 3.53442931 |
46 | detection of calcium ion (GO:0005513) | 3.53315783 |
47 | response to histamine (GO:0034776) | 3.51215394 |
48 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.50047081 |
49 | regulation of glutamate secretion (GO:0014048) | 3.45240961 |
50 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.45044882 |
51 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.42280740 |
52 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.40587535 |
53 | regulation of synapse structural plasticity (GO:0051823) | 3.40313410 |
54 | behavioral response to nicotine (GO:0035095) | 3.36920058 |
55 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.36772520 |
56 | regulation of cell communication by electrical coupling (GO:0010649) | 3.36258085 |
57 | regulation of postsynaptic membrane potential (GO:0060078) | 3.35482337 |
58 | positive regulation of synapse assembly (GO:0051965) | 3.34322144 |
59 | dendritic spine morphogenesis (GO:0060997) | 3.33089910 |
60 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.32975963 |
61 | long-term memory (GO:0007616) | 3.26848515 |
62 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.25663939 |
63 | mitochondrion transport along microtubule (GO:0047497) | 3.25663939 |
64 | positive regulation of membrane potential (GO:0045838) | 3.24878345 |
65 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.22647961 |
66 | synapse assembly (GO:0007416) | 3.21834295 |
67 | layer formation in cerebral cortex (GO:0021819) | 3.21821371 |
68 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.20962275 |
69 | female mating behavior (GO:0060180) | 3.19281389 |
70 | behavioral fear response (GO:0001662) | 3.19054570 |
71 | behavioral defense response (GO:0002209) | 3.19054570 |
72 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.18930849 |
73 | regulation of neurotransmitter secretion (GO:0046928) | 3.18362868 |
74 | regulation of neurotransmitter levels (GO:0001505) | 3.18205329 |
75 | response to auditory stimulus (GO:0010996) | 3.18163608 |
76 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.17843873 |
77 | regulation of female receptivity (GO:0045924) | 3.16383385 |
78 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.16096796 |
79 | opioid receptor signaling pathway (GO:0038003) | 3.15077022 |
80 | long-term synaptic potentiation (GO:0060291) | 3.13594275 |
81 | regulation of membrane repolarization (GO:0060306) | 3.13454116 |
82 | cell communication involved in cardiac conduction (GO:0086065) | 3.12996228 |
83 | startle response (GO:0001964) | 3.12047159 |
84 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.10761194 |
85 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.09033181 |
86 | neurofilament cytoskeleton organization (GO:0060052) | 3.08624894 |
87 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.08174282 |
88 | cerebellar granule cell differentiation (GO:0021707) | 3.06752534 |
89 | regulation of synaptic plasticity (GO:0048167) | 3.05356063 |
90 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.04569423 |
91 | cell communication by electrical coupling (GO:0010644) | 3.04146169 |
92 | regulation of vesicle fusion (GO:0031338) | 3.04125092 |
93 | auditory behavior (GO:0031223) | 3.01984230 |
94 | positive regulation of synapse maturation (GO:0090129) | 3.01909003 |
95 | cellular potassium ion homeostasis (GO:0030007) | 3.00916317 |
96 | regulation of synaptic transmission, GABAergic (GO:0032228) | 3.00669336 |
97 | membrane depolarization during action potential (GO:0086010) | 2.99799207 |
98 | membrane depolarization (GO:0051899) | 2.98753982 |
99 | regulation of respiratory system process (GO:0044065) | 2.98108062 |
100 | membrane hyperpolarization (GO:0060081) | 2.96848195 |
101 | activation of protein kinase A activity (GO:0034199) | 2.96030310 |
102 | fear response (GO:0042596) | 2.95631165 |
103 | muscle filament sliding (GO:0030049) | 2.94831804 |
104 | actin-myosin filament sliding (GO:0033275) | 2.94831804 |
105 | learning (GO:0007612) | 2.94470664 |
106 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.93253749 |
107 | synaptic transmission (GO:0007268) | 2.92298639 |
108 | vesicle transport along microtubule (GO:0047496) | 2.91621514 |
109 | regulation of neurotransmitter transport (GO:0051588) | 2.91466214 |
110 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.90399616 |
111 | innervation (GO:0060384) | 2.87734682 |
112 | regulation of synapse assembly (GO:0051963) | 2.87017591 |
113 | cell migration in hindbrain (GO:0021535) | 2.86757497 |
114 | cardiac muscle contraction (GO:0060048) | 2.86666874 |
115 | regulation of relaxation of muscle (GO:1901077) | 2.84763278 |
116 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.84078035 |
117 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.83904724 |
118 | positive regulation of neurotransmitter transport (GO:0051590) | 2.83669543 |
119 | regulation of synaptic transmission (GO:0050804) | 2.81862570 |
120 | negative regulation of amino acid transport (GO:0051956) | 2.81833478 |
121 | regulation of protein kinase A signaling (GO:0010738) | 2.81383743 |
122 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.81017619 |
123 | positive regulation of synaptic transmission (GO:0050806) | 2.80828792 |
124 | neuromuscular synaptic transmission (GO:0007274) | 2.80296859 |
125 | dendrite development (GO:0016358) | 2.79951243 |
126 | negative regulation of dendrite development (GO:2000171) | 2.79763783 |
127 | neuromuscular process controlling posture (GO:0050884) | 2.79636870 |
128 | dendrite morphogenesis (GO:0048813) | 2.79316976 |
129 | intraspecies interaction between organisms (GO:0051703) | 2.78908274 |
130 | sarcomere organization (GO:0045214) | 2.76918356 |
131 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.73118094 |
132 | mechanosensory behavior (GO:0007638) | 2.73012115 |
133 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.70771865 |
134 | dendritic spine organization (GO:0097061) | 2.65239842 |
135 | glycosphingolipid biosynthetic process (GO:0006688) | 2.64756374 |
136 | neuronal ion channel clustering (GO:0045161) | 2.64503801 |
137 | synapse organization (GO:0050808) | 2.62705788 |
138 | positive regulation of sodium ion transport (GO:0010765) | 2.62462098 |
139 | regulation of actin filament-based movement (GO:1903115) | 2.61573426 |
140 | cardiac ventricle formation (GO:0003211) | 2.61214913 |
141 | negative regulation of heart rate (GO:0010459) | 2.60383819 |
142 | retinal ganglion cell axon guidance (GO:0031290) | 2.58701075 |
143 | regulation of dendritic spine development (GO:0060998) | 2.58466393 |
144 | cardiac muscle hypertrophy (GO:0003300) | 2.58351715 |
145 | multicellular organismal signaling (GO:0035637) | 2.57210320 |
146 | cardiac chamber formation (GO:0003207) | 2.53809127 |
147 | action potential (GO:0001508) | 2.53116067 |
148 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.52891847 |
149 | cardiac myofibril assembly (GO:0055003) | 2.52601525 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.71076673 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.15317230 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.98449617 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.88669159 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.83564850 |
6 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.52391661 |
7 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.51161215 |
8 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.45887672 |
9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.42927705 |
10 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.42726194 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.40755815 |
12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.40755815 |
13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.40735403 |
14 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.31526742 |
15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.28368612 |
16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.27921113 |
17 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.26585395 |
18 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.16492322 |
19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.14628775 |
20 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.13291718 |
21 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.03653200 |
22 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.02192489 |
23 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.00327409 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.98756307 |
25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.98018288 |
26 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.97861482 |
27 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.97660710 |
28 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.95364185 |
29 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.90189736 |
30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.88522391 |
31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.88420762 |
32 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.87597238 |
33 | P300_19829295_ChIP-Seq_ESCs_Human | 1.85459284 |
34 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.81425694 |
35 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.77667742 |
36 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.76205239 |
37 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.75226741 |
38 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.74667370 |
39 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.70399614 |
40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.68968984 |
41 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.68244246 |
42 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.66072930 |
43 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.60376659 |
44 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.53621044 |
45 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.51209280 |
46 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.50850982 |
47 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.49170289 |
48 | AR_25329375_ChIP-Seq_VCAP_Human | 1.46296355 |
49 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.44406118 |
50 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.43936954 |
51 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.42597255 |
52 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.42317272 |
53 | VDR_22108803_ChIP-Seq_LS180_Human | 1.42013432 |
54 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.41956180 |
55 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39076767 |
56 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.35797115 |
57 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.35574630 |
58 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33816260 |
59 | STAT3_23295773_ChIP-Seq_U87_Human | 1.33644155 |
60 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.33514354 |
61 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.31149126 |
62 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.30405462 |
63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29991600 |
64 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.29974443 |
65 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.27954787 |
66 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.24798083 |
67 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.24576693 |
68 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.22863368 |
69 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.21361932 |
70 | TCF4_23295773_ChIP-Seq_U87_Human | 1.20822295 |
71 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20317277 |
72 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.19472664 |
73 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.19092757 |
74 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.18113600 |
75 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.18113600 |
76 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.17806005 |
77 | JUN_21703547_ChIP-Seq_K562_Human | 1.16263157 |
78 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.15949118 |
79 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.15129517 |
80 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.11839502 |
81 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.11325050 |
82 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.09830892 |
83 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.09426083 |
84 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.08690524 |
85 | AR_19668381_ChIP-Seq_PC3_Human | 1.08034497 |
86 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.07682844 |
87 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.05903670 |
88 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.05883216 |
89 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.05820799 |
90 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.05607067 |
91 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.05341905 |
92 | * FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.05263633 |
93 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.04073059 |
94 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03607510 |
95 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.02961453 |
96 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02960733 |
97 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.02358145 |
98 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02358145 |
99 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.01990241 |
100 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.01582539 |
101 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.00656873 |
102 | EWS_26573619_Chip-Seq_HEK293_Human | 0.99777736 |
103 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.99539257 |
104 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.98302899 |
105 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.98291148 |
106 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.98116913 |
107 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.97884237 |
108 | KDM2B_26808549_Chip-Seq_REH_Human | 0.97025764 |
109 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.96877676 |
110 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.96076176 |
111 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.95712075 |
112 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.95204058 |
113 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95172400 |
114 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.94358579 |
115 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.93492116 |
116 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.93129347 |
117 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.92653164 |
118 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.90889068 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.32055312 |
2 | MP0004859_abnormal_synaptic_plasticity | 5.06339903 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.67304762 |
4 | MP0001968_abnormal_touch/_nociception | 3.43263050 |
5 | MP0004270_analgesia | 3.36569242 |
6 | MP0009745_abnormal_behavioral_response | 3.29503124 |
7 | MP0005423_abnormal_somatic_nervous | 3.11852068 |
8 | MP0002063_abnormal_learning/memory/cond | 3.07284263 |
9 | MP0006276_abnormal_autonomic_nervous | 3.05069832 |
10 | MP0002064_seizures | 2.95274124 |
11 | MP0002735_abnormal_chemical_nociception | 2.91551497 |
12 | MP0009046_muscle_twitch | 2.87407619 |
13 | MP0002736_abnormal_nociception_after | 2.82975707 |
14 | MP0002572_abnormal_emotion/affect_behav | 2.76184980 |
15 | MP0002734_abnormal_mechanical_nocicepti | 2.69264616 |
16 | MP0002272_abnormal_nervous_system | 2.51691469 |
17 | MP0001486_abnormal_startle_reflex | 2.42498218 |
18 | MP0001440_abnormal_grooming_behavior | 2.31145994 |
19 | MP0002822_catalepsy | 2.25635356 |
20 | MP0005645_abnormal_hypothalamus_physiol | 2.22715105 |
21 | MP0001501_abnormal_sleep_pattern | 2.19633847 |
22 | MP0002733_abnormal_thermal_nociception | 2.14553410 |
23 | MP0005646_abnormal_pituitary_gland | 2.10752281 |
24 | MP0002067_abnormal_sensory_capabilities | 2.09791114 |
25 | MP0001970_abnormal_pain_threshold | 2.07551122 |
26 | MP0001529_abnormal_vocalization | 2.05178829 |
27 | MP0000778_abnormal_nervous_system | 1.94034982 |
28 | MP0002184_abnormal_innervation | 1.93694806 |
29 | MP0001188_hyperpigmentation | 1.85758747 |
30 | MP0003122_maternal_imprinting | 1.85195793 |
31 | MP0005386_behavior/neurological_phenoty | 1.81592842 |
32 | MP0004924_abnormal_behavior | 1.81592842 |
33 | MP0002557_abnormal_social/conspecific_i | 1.79181315 |
34 | MP0004084_abnormal_cardiac_muscle | 1.76962578 |
35 | MP0001984_abnormal_olfaction | 1.75550651 |
36 | MP0003787_abnormal_imprinting | 1.72963966 |
37 | MP0004142_abnormal_muscle_tone | 1.61543992 |
38 | MP0009780_abnormal_chondrocyte_physiolo | 1.59964877 |
39 | MP0001905_abnormal_dopamine_level | 1.54880283 |
40 | MP0001502_abnormal_circadian_rhythm | 1.53466772 |
41 | MP0004858_abnormal_nervous_system | 1.50858222 |
42 | MP0004811_abnormal_neuron_physiology | 1.50471180 |
43 | MP0008877_abnormal_DNA_methylation | 1.48289391 |
44 | MP0000955_abnormal_spinal_cord | 1.42053356 |
45 | MP0008569_lethality_at_weaning | 1.40115958 |
46 | MP0003879_abnormal_hair_cell | 1.39945103 |
47 | MP0000749_muscle_degeneration | 1.38096013 |
48 | MP0002909_abnormal_adrenal_gland | 1.37038404 |
49 | MP0002066_abnormal_motor_capabilities/c | 1.33403721 |
50 | MP0002882_abnormal_neuron_morphology | 1.33227711 |
51 | MP0008775_abnormal_heart_ventricle | 1.31753513 |
52 | MP0004742_abnormal_vestibular_system | 1.29474797 |
53 | MP0004036_abnormal_muscle_relaxation | 1.28980420 |
54 | MP0003329_amyloid_beta_deposits | 1.27160924 |
55 | MP0002876_abnormal_thyroid_physiology | 1.26966213 |
56 | MP0004885_abnormal_endolymph | 1.20669642 |
57 | MP0005620_abnormal_muscle_contractility | 1.18653723 |
58 | MP0010386_abnormal_urinary_bladder | 1.17897347 |
59 | MP0002106_abnormal_muscle_physiology | 1.17880704 |
60 | MP0003633_abnormal_nervous_system | 1.16081481 |
61 | MP0001986_abnormal_taste_sensitivity | 1.11726392 |
62 | MP0002638_abnormal_pupillary_reflex | 1.07147230 |
63 | MP0005551_abnormal_eye_electrophysiolog | 1.05605414 |
64 | MP0002972_abnormal_cardiac_muscle | 1.05209426 |
65 | MP0003646_muscle_fatigue | 1.04775101 |
66 | MP0004130_abnormal_muscle_cell | 0.99418191 |
67 | MP0002229_neurodegeneration | 0.98653265 |
68 | MP0001963_abnormal_hearing_physiology | 0.97600668 |
69 | MP0005369_muscle_phenotype | 0.97450100 |
70 | MP0002152_abnormal_brain_morphology | 0.96474426 |
71 | MP0003123_paternal_imprinting | 0.96134963 |
72 | MP0003631_nervous_system_phenotype | 0.94679931 |
73 | MP0002837_dystrophic_cardiac_calcinosis | 0.93168672 |
74 | MP0000631_abnormal_neuroendocrine_gland | 0.92174285 |
75 | MP0002069_abnormal_eating/drinking_beha | 0.91159289 |
76 | MP0005187_abnormal_penis_morphology | 0.91028633 |
77 | MP0005394_taste/olfaction_phenotype | 0.89441045 |
78 | MP0005499_abnormal_olfactory_system | 0.89441045 |
79 | MP0000750_abnormal_muscle_regeneration | 0.89209222 |
80 | MP0004510_myositis | 0.88369974 |
81 | MP0002234_abnormal_pharynx_morphology | 0.86359482 |
82 | MP0002752_abnormal_somatic_nervous | 0.84412027 |
83 | MP0005171_absent_coat_pigmentation | 0.83535810 |
84 | MP0004085_abnormal_heartbeat | 0.83236807 |
85 | MP0005330_cardiomyopathy | 0.81417709 |
86 | MP0003634_abnormal_glial_cell | 0.80784421 |
87 | MP0005535_abnormal_body_temperature | 0.80310824 |
88 | MP0006292_abnormal_olfactory_placode | 0.79625700 |
89 | MP0003121_genomic_imprinting | 0.79523177 |
90 | MP0008872_abnormal_physiological_respon | 0.79275963 |
91 | MP0008874_decreased_physiological_sensi | 0.79253618 |
92 | MP0002332_abnormal_exercise_endurance | 0.77403614 |
93 | MP0004147_increased_porphyrin_level | 0.76189872 |
94 | MP0000569_abnormal_digit_pigmentation | 0.75539575 |
95 | MP0004087_abnormal_muscle_fiber | 0.75418872 |
96 | MP0000751_myopathy | 0.74057628 |
97 | MP0001485_abnormal_pinna_reflex | 0.73866568 |
98 | MP0005379_endocrine/exocrine_gland_phen | 0.73401806 |
99 | MP0004133_heterotaxia | 0.71226688 |
100 | MP0001177_atelectasis | 0.70795312 |
101 | MP0001664_abnormal_digestion | 0.69440424 |
102 | MP0005409_darkened_coat_color | 0.68863153 |
103 | MP0004145_abnormal_muscle_electrophysio | 0.68333934 |
104 | MP0003183_abnormal_peptide_metabolism | 0.67516268 |
105 | MP0000026_abnormal_inner_ear | 0.67120532 |
106 | MP0000920_abnormal_myelination | 0.66956021 |
107 | MP0006072_abnormal_retinal_apoptosis | 0.65335420 |
108 | MP0003690_abnormal_glial_cell | 0.64031090 |
109 | MP0002163_abnormal_gland_morphology | 0.61893275 |
110 | MP0002751_abnormal_autonomic_nervous | 0.60955120 |
111 | MP0001299_abnormal_eye_distance/ | 0.60918759 |
112 | MP0004484_altered_response_of | 0.60397987 |
113 | MP0003137_abnormal_impulse_conducting | 0.59314222 |
114 | MP0004215_abnormal_myocardial_fiber | 0.57193917 |
115 | MP0005253_abnormal_eye_physiology | 0.55856848 |
116 | MP0000013_abnormal_adipose_tissue | 0.55735853 |
117 | MP0001943_abnormal_respiration | 0.53899887 |
118 | MP0003632_abnormal_nervous_system | 0.53804498 |
119 | MP0002090_abnormal_vision | 0.52406403 |
120 | MP0000604_amyloidosis | 0.51248396 |
121 | MP0002102_abnormal_ear_morphology | 0.48563088 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.53827891 |
2 | Myokymia (HP:0002411) | 5.63423973 |
3 | Focal seizures (HP:0007359) | 5.33270336 |
4 | Febrile seizures (HP:0002373) | 5.15398960 |
5 | Epileptic encephalopathy (HP:0200134) | 4.98257352 |
6 | Atonic seizures (HP:0010819) | 4.85725092 |
7 | Visual hallucinations (HP:0002367) | 4.78784384 |
8 | Hyperventilation (HP:0002883) | 4.36147724 |
9 | Absence seizures (HP:0002121) | 4.31508209 |
10 | Dialeptic seizures (HP:0011146) | 4.02565761 |
11 | Progressive cerebellar ataxia (HP:0002073) | 3.98822434 |
12 | Generalized tonic-clonic seizures (HP:0002069) | 3.96986173 |
13 | Broad-based gait (HP:0002136) | 3.73314629 |
14 | Bundle branch block (HP:0011710) | 3.57463143 |
15 | Sudden death (HP:0001699) | 3.53090313 |
16 | Calf muscle hypertrophy (HP:0008981) | 3.47709372 |
17 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.28232119 |
18 | Supranuclear gaze palsy (HP:0000605) | 3.27282157 |
19 | Excessive salivation (HP:0003781) | 3.18475444 |
20 | Drooling (HP:0002307) | 3.18475444 |
21 | Abnormal eating behavior (HP:0100738) | 3.15890461 |
22 | Atrial fibrillation (HP:0005110) | 3.10859824 |
23 | Progressive inability to walk (HP:0002505) | 3.10218610 |
24 | Truncal ataxia (HP:0002078) | 3.09942809 |
25 | Polyphagia (HP:0002591) | 3.04096387 |
26 | Primary atrial arrhythmia (HP:0001692) | 3.03169586 |
27 | Abnormality of the calf musculature (HP:0001430) | 3.02416460 |
28 | Syncope (HP:0001279) | 3.00588901 |
29 | Limb dystonia (HP:0002451) | 2.97369271 |
30 | Mutism (HP:0002300) | 2.96112341 |
31 | Supraventricular tachycardia (HP:0004755) | 2.92836522 |
32 | Poor eye contact (HP:0000817) | 2.89704278 |
33 | Anxiety (HP:0000739) | 2.89609271 |
34 | Ankle clonus (HP:0011448) | 2.87274613 |
35 | Pheochromocytoma (HP:0002666) | 2.85997090 |
36 | Gaze-evoked nystagmus (HP:0000640) | 2.85326791 |
37 | Fetal akinesia sequence (HP:0001989) | 2.84863107 |
38 | Supraventricular arrhythmia (HP:0005115) | 2.83035950 |
39 | Action tremor (HP:0002345) | 2.82923401 |
40 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.80518682 |
41 | Rimmed vacuoles (HP:0003805) | 2.80408441 |
42 | Amblyopia (HP:0000646) | 2.74084161 |
43 | Ulnar claw (HP:0001178) | 2.73464643 |
44 | Abnormal hair whorl (HP:0010721) | 2.72202889 |
45 | Inability to walk (HP:0002540) | 2.65391660 |
46 | Left ventricular hypertrophy (HP:0001712) | 2.61720150 |
47 | Protruding tongue (HP:0010808) | 2.57732464 |
48 | Impaired social interactions (HP:0000735) | 2.56793738 |
49 | Abnormal social behavior (HP:0012433) | 2.56793738 |
50 | Prolonged QT interval (HP:0001657) | 2.56546233 |
51 | Gait imbalance (HP:0002141) | 2.54492887 |
52 | Neuroendocrine neoplasm (HP:0100634) | 2.52248291 |
53 | Abnormality of the corticospinal tract (HP:0002492) | 2.51817763 |
54 | Depression (HP:0000716) | 2.51766543 |
55 | Epileptiform EEG discharges (HP:0011182) | 2.49809416 |
56 | Dysmetria (HP:0001310) | 2.48748360 |
57 | Absent speech (HP:0001344) | 2.46454583 |
58 | Scanning speech (HP:0002168) | 2.43234555 |
59 | Blue irides (HP:0000635) | 2.42182160 |
60 | Hemiparesis (HP:0001269) | 2.42084564 |
61 | Vaginal atresia (HP:0000148) | 2.39014092 |
62 | Poor suck (HP:0002033) | 2.37644329 |
63 | Dysdiadochokinesis (HP:0002075) | 2.37473231 |
64 | Exercise-induced muscle cramps (HP:0003710) | 2.37243601 |
65 | Failure to thrive in infancy (HP:0001531) | 2.36134962 |
66 | EEG with generalized epileptiform discharges (HP:0011198) | 2.35640948 |
67 | Diplopia (HP:0000651) | 2.34811137 |
68 | Abnormality of binocular vision (HP:0011514) | 2.34811137 |
69 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.34447409 |
70 | Pachygyria (HP:0001302) | 2.34109514 |
71 | Agitation (HP:0000713) | 2.29420577 |
72 | Termporal pattern (HP:0011008) | 2.27588723 |
73 | Insidious onset (HP:0003587) | 2.27588723 |
74 | Postural instability (HP:0002172) | 2.24364207 |
75 | Abnormality of salivation (HP:0100755) | 2.24318385 |
76 | Esotropia (HP:0000565) | 2.24169927 |
77 | Retinal dysplasia (HP:0007973) | 2.23259114 |
78 | Hypsarrhythmia (HP:0002521) | 2.18535087 |
79 | Muscle fiber inclusion bodies (HP:0100299) | 2.17093853 |
80 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.16803572 |
81 | Absent/shortened dynein arms (HP:0200106) | 2.16803572 |
82 | Medial flaring of the eyebrow (HP:0010747) | 2.16453288 |
83 | Akinesia (HP:0002304) | 2.15673002 |
84 | Urinary urgency (HP:0000012) | 2.13379267 |
85 | Spastic gait (HP:0002064) | 2.13205669 |
86 | Generalized hypopigmentation of hair (HP:0011358) | 2.11985633 |
87 | Nephronophthisis (HP:0000090) | 2.11617484 |
88 | Bradykinesia (HP:0002067) | 2.10324427 |
89 | Papilledema (HP:0001085) | 2.10077300 |
90 | Hypothermia (HP:0002045) | 2.09568406 |
91 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.09280311 |
92 | Heart block (HP:0012722) | 2.09245194 |
93 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.08198470 |
94 | Cerebral inclusion bodies (HP:0100314) | 2.07486145 |
95 | Neurofibrillary tangles (HP:0002185) | 2.06536463 |
96 | EMG: neuropathic changes (HP:0003445) | 2.06501260 |
97 | Congenital primary aphakia (HP:0007707) | 2.03635240 |
98 | Psychosis (HP:0000709) | 2.03368590 |
99 | Hyporeflexia of lower limbs (HP:0002600) | 2.02311316 |
100 | Torticollis (HP:0000473) | 2.02016197 |
101 | Muscle fiber splitting (HP:0003555) | 2.01390029 |
102 | Type II lissencephaly (HP:0007260) | 2.00355602 |
103 | Specific learning disability (HP:0001328) | 1.99426399 |
104 | Lower limb muscle weakness (HP:0007340) | 1.98703874 |
105 | Nephrogenic diabetes insipidus (HP:0009806) | 1.98563333 |
106 | Nemaline bodies (HP:0003798) | 1.97942384 |
107 | Sleep apnea (HP:0010535) | 1.97234452 |
108 | Spastic tetraplegia (HP:0002510) | 1.97211064 |
109 | Molar tooth sign on MRI (HP:0002419) | 1.97017836 |
110 | Abnormality of midbrain morphology (HP:0002418) | 1.97017836 |
111 | EMG: myopathic abnormalities (HP:0003458) | 1.95959248 |
112 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.95521294 |
113 | Subaortic stenosis (HP:0001682) | 1.95521294 |
114 | Generalized myoclonic seizures (HP:0002123) | 1.95479652 |
115 | Frequent falls (HP:0002359) | 1.94376559 |
116 | Amyotrophic lateral sclerosis (HP:0007354) | 1.93738816 |
117 | Myotonia (HP:0002486) | 1.91053729 |
118 | Hypoventilation (HP:0002791) | 1.90860338 |
119 | Incomplete penetrance (HP:0003829) | 1.90130318 |
120 | Steppage gait (HP:0003376) | 1.89843936 |
121 | Stereotypic behavior (HP:0000733) | 1.89265630 |
122 | Abnormal ciliary motility (HP:0012262) | 1.86856503 |
123 | Distal arthrogryposis (HP:0005684) | 1.86411419 |
124 | Ventricular fibrillation (HP:0001663) | 1.85423341 |
125 | Progressive macrocephaly (HP:0004481) | 1.85302917 |
126 | Ventricular arrhythmia (HP:0004308) | 1.83579714 |
127 | Focal dystonia (HP:0004373) | 1.83026282 |
128 | Poor coordination (HP:0002370) | 1.82805366 |
129 | Ventricular tachycardia (HP:0004756) | 1.82434412 |
130 | Gait ataxia (HP:0002066) | 1.82254586 |
131 | Status epilepticus (HP:0002133) | 1.82118530 |
132 | Muscular hypotonia of the trunk (HP:0008936) | 1.81471615 |
133 | Abnormal EKG (HP:0003115) | 1.80262769 |
134 | Fair hair (HP:0002286) | 1.79783199 |
135 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.79602831 |
136 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.79602831 |
137 | Bradycardia (HP:0001662) | 1.79367132 |
138 | Genital tract atresia (HP:0001827) | 1.79053402 |
139 | Widely spaced teeth (HP:0000687) | 1.78562680 |
140 | Exotropia (HP:0000577) | 1.77397795 |
141 | Genetic anticipation (HP:0003743) | 1.77101006 |
142 | Impaired smooth pursuit (HP:0007772) | 1.75706460 |
143 | Hypoplasia of the brainstem (HP:0002365) | 1.75312664 |
144 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.75312664 |
145 | Hyperthyroidism (HP:0000836) | 1.74054761 |
146 | Lissencephaly (HP:0001339) | 1.73825640 |
147 | Acute necrotizing encephalopathy (HP:0006965) | 1.73176763 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.54094749 |
2 | MARK1 | 3.70873395 |
3 | CASK | 3.68264774 |
4 | MAP3K12 | 3.49393580 |
5 | EPHA4 | 3.08990129 |
6 | MAP3K4 | 3.06996550 |
7 | OBSCN | 2.95336429 |
8 | MAP2K7 | 2.95259817 |
9 | MINK1 | 2.72918555 |
10 | MAP3K9 | 2.68525527 |
11 | MAP4K2 | 2.63748904 |
12 | TNIK | 2.38917136 |
13 | FRK | 2.31576432 |
14 | SIK3 | 2.15711360 |
15 | MAP2K4 | 2.05204381 |
16 | MAPK13 | 1.89547274 |
17 | NTRK2 | 1.84548007 |
18 | RIPK4 | 1.77577954 |
19 | PRPF4B | 1.71826063 |
20 | PLK2 | 1.71278000 |
21 | GRK5 | 1.63657101 |
22 | ARAF | 1.62426768 |
23 | SIK2 | 1.59164753 |
24 | EPHA3 | 1.59103247 |
25 | DAPK2 | 1.55930729 |
26 | TRIM28 | 1.54332442 |
27 | PAK6 | 1.47146307 |
28 | KSR1 | 1.43394469 |
29 | PNCK | 1.38959691 |
30 | NTRK1 | 1.31618360 |
31 | CDK5 | 1.31043544 |
32 | PRKCG | 1.26374208 |
33 | SGK223 | 1.18578012 |
34 | SGK494 | 1.18578012 |
35 | DAPK1 | 1.17436872 |
36 | SGK2 | 1.15334920 |
37 | KSR2 | 1.13704621 |
38 | LIMK1 | 1.12329222 |
39 | CAMK2A | 1.12034602 |
40 | FES | 1.10924028 |
41 | ADRBK2 | 1.08907876 |
42 | BCR | 1.08830136 |
43 | CAMKK2 | 1.06310299 |
44 | BMPR2 | 1.04911837 |
45 | PHKG2 | 1.02370680 |
46 | PHKG1 | 1.02370680 |
47 | CAMKK1 | 0.97755664 |
48 | CSNK1A1L | 0.97557462 |
49 | UHMK1 | 0.95252822 |
50 | CDK19 | 0.94813067 |
51 | DMPK | 0.94540349 |
52 | AKT3 | 0.91816550 |
53 | CSNK1G1 | 0.91259673 |
54 | CAMK4 | 0.89670095 |
55 | MYLK | 0.89004875 |
56 | LATS2 | 0.88162798 |
57 | NME1 | 0.87937021 |
58 | CAMK2B | 0.87848413 |
59 | GRK7 | 0.87648112 |
60 | WNK3 | 0.85602738 |
61 | OXSR1 | 0.85131258 |
62 | PRKCE | 0.80153063 |
63 | TNK2 | 0.77815925 |
64 | PAK3 | 0.76326205 |
65 | MAP3K2 | 0.74529532 |
66 | CSNK1G2 | 0.73901674 |
67 | CDK18 | 0.71610255 |
68 | ERBB3 | 0.70673143 |
69 | DYRK1A | 0.68546968 |
70 | MAP3K13 | 0.67620378 |
71 | CDK14 | 0.67285451 |
72 | SGK3 | 0.66443022 |
73 | FGR | 0.65689258 |
74 | FGFR2 | 0.64125188 |
75 | BRAF | 0.63994439 |
76 | STK38 | 0.63621429 |
77 | SGK1 | 0.62816636 |
78 | CDK15 | 0.62725031 |
79 | DYRK2 | 0.61680652 |
80 | CAMK1 | 0.61321541 |
81 | PTK2B | 0.61302449 |
82 | PRKD3 | 0.60570482 |
83 | PRKACA | 0.60569972 |
84 | MAP3K5 | 0.60379564 |
85 | CAMK2D | 0.59990077 |
86 | TAOK1 | 0.59556319 |
87 | PRKCH | 0.59462577 |
88 | PRKAA1 | 0.58290278 |
89 | ADRBK1 | 0.57696989 |
90 | MUSK | 0.56224967 |
91 | MAPK12 | 0.55466139 |
92 | CCNB1 | 0.54948834 |
93 | MAPKAPK5 | 0.53817878 |
94 | MAP3K7 | 0.53675816 |
95 | CAMK2G | 0.52986157 |
96 | EPHB2 | 0.52054925 |
97 | CDK11A | 0.51855411 |
98 | PRKCZ | 0.50797345 |
99 | PRKG1 | 0.50172068 |
100 | WNK1 | 0.50021679 |
101 | DYRK3 | 0.49940116 |
102 | MAP3K6 | 0.49377932 |
103 | BMPR1B | 0.47961878 |
104 | MARK2 | 0.47344363 |
105 | RPS6KA2 | 0.46803704 |
106 | STK11 | 0.46713797 |
107 | FER | 0.46519138 |
108 | RET | 0.46180254 |
109 | RAF1 | 0.46146442 |
110 | PKN1 | 0.45890767 |
111 | PINK1 | 0.45616657 |
112 | YES1 | 0.43840554 |
113 | LMTK2 | 0.43485168 |
114 | GRK1 | 0.42646850 |
115 | TAOK3 | 0.41925407 |
116 | TTN | 0.41504967 |
117 | NEK6 | 0.41503208 |
118 | MAP2K1 | 0.41367120 |
119 | PRKACB | 0.39683485 |
120 | CDK3 | 0.39365743 |
121 | BCKDK | 0.38692681 |
122 | CSNK1G3 | 0.38597850 |
123 | RPS6KA3 | 0.38157250 |
124 | MAP3K1 | 0.38044889 |
125 | CSNK1D | 0.37676708 |
126 | INSRR | 0.37601039 |
127 | STK39 | 0.37417005 |
128 | MAPK4 | 0.36798146 |
129 | DYRK1B | 0.36531243 |
130 | MAP2K6 | 0.36409356 |
131 | PRKD1 | 0.35891618 |
132 | TESK1 | 0.34737021 |
133 | PIK3CA | 0.34716738 |
134 | ROCK1 | 0.33779033 |
135 | CSNK1E | 0.32805371 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.48613786 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.44304445 |
3 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.89019884 |
4 | GABAergic synapse_Homo sapiens_hsa04727 | 2.85395685 |
5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.70775398 |
6 | Morphine addiction_Homo sapiens_hsa05032 | 2.66243161 |
7 | Circadian entrainment_Homo sapiens_hsa04713 | 2.55280317 |
8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.47287448 |
9 | Long-term potentiation_Homo sapiens_hsa04720 | 2.44555617 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.29491593 |
11 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.21610092 |
12 | Taste transduction_Homo sapiens_hsa04742 | 2.16310502 |
13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.11740531 |
14 | Serotonergic synapse_Homo sapiens_hsa04726 | 2.02799104 |
15 | Insulin secretion_Homo sapiens_hsa04911 | 1.91498285 |
16 | Salivary secretion_Homo sapiens_hsa04970 | 1.90538856 |
17 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.84993858 |
18 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.80350990 |
19 | Renin secretion_Homo sapiens_hsa04924 | 1.74381919 |
20 | Long-term depression_Homo sapiens_hsa04730 | 1.70735456 |
21 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.67683553 |
22 | Cocaine addiction_Homo sapiens_hsa05030 | 1.66112134 |
23 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.62936836 |
24 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.57989771 |
25 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.57800282 |
26 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.52671837 |
27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.51722210 |
28 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.45506165 |
29 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.41463727 |
30 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.37819386 |
31 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.36411572 |
32 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.27639673 |
33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.26543391 |
34 | Phototransduction_Homo sapiens_hsa04744 | 1.26520656 |
35 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.25965297 |
36 | Axon guidance_Homo sapiens_hsa04360 | 1.23939283 |
37 | Alzheimers disease_Homo sapiens_hsa05010 | 1.22184918 |
38 | Protein export_Homo sapiens_hsa03060 | 1.20064450 |
39 | Gap junction_Homo sapiens_hsa04540 | 1.18860176 |
40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.18443318 |
41 | Parkinsons disease_Homo sapiens_hsa05012 | 1.13897061 |
42 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.13537084 |
43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.13295661 |
44 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.10869476 |
45 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.09805432 |
46 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.03120037 |
47 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.99252139 |
48 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.96292125 |
49 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.95997460 |
50 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.95319307 |
51 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.91010605 |
52 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.88604162 |
53 | Melanogenesis_Homo sapiens_hsa04916 | 0.87436439 |
54 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.85337432 |
55 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84869782 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.83432231 |
57 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.81972472 |
58 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.81838875 |
59 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.80653890 |
60 | Glioma_Homo sapiens_hsa05214 | 0.80542071 |
61 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.79535734 |
62 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.79503858 |
63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.77928915 |
64 | Huntingtons disease_Homo sapiens_hsa05016 | 0.76682846 |
65 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.76289258 |
66 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.74108874 |
67 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70861777 |
68 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.69915926 |
69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67616842 |
70 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.67213317 |
71 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.66755248 |
72 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.66331100 |
73 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.65823439 |
74 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.64813133 |
75 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.63176307 |
76 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.59916743 |
77 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.59116217 |
78 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.58070299 |
79 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.57492047 |
80 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.56936837 |
81 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.56615214 |
82 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.55510417 |
83 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.54861078 |
84 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.54395549 |
85 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.54332232 |
86 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51562139 |
87 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.49290360 |
88 | Peroxisome_Homo sapiens_hsa04146 | 0.49251990 |
89 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.48950468 |
90 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.48875660 |
91 | Tight junction_Homo sapiens_hsa04530 | 0.48559847 |
92 | Phagosome_Homo sapiens_hsa04145 | 0.48472836 |
93 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.48223133 |
94 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.48192157 |
95 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.47772196 |
96 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.46808860 |
97 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.46505464 |
98 | Alcoholism_Homo sapiens_hsa05034 | 0.45972809 |
99 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.43493258 |
100 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.43338054 |
101 | Circadian rhythm_Homo sapiens_hsa04710 | 0.43026366 |
102 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.42746625 |
103 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.42049503 |
104 | Prion diseases_Homo sapiens_hsa05020 | 0.40906540 |
105 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40789895 |
106 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.40599594 |
107 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.39404255 |
108 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.38981598 |
109 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.38529996 |
110 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.36816740 |
111 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36177485 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.35014695 |
113 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34769496 |
114 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.34200732 |
115 | Endometrial cancer_Homo sapiens_hsa05213 | 0.33215777 |
116 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.32055718 |
117 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.30656895 |
118 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.29643054 |
119 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.29547227 |
120 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.28975114 |
121 | Melanoma_Homo sapiens_hsa05218 | 0.28826072 |
122 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.28164837 |
123 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.26506912 |
124 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.25460640 |
125 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.25004202 |
126 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.24319813 |
127 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.22514856 |