RABEPK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of 5.8S rRNA (GO:0000460)5.67476980
2ribosomal small subunit assembly (GO:0000028)5.23142298
3DNA deamination (GO:0045006)5.21797623
4mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.05298085
5cell wall macromolecule catabolic process (GO:0016998)4.67207017
6cell wall macromolecule metabolic process (GO:0044036)4.67207017
7establishment of protein localization to mitochondrial membrane (GO:0090151)4.61404241
8ATP synthesis coupled proton transport (GO:0015986)4.51634484
9energy coupled proton transport, down electrochemical gradient (GO:0015985)4.51634484
10proteasome assembly (GO:0043248)4.49797600
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.19862631
12chaperone-mediated protein transport (GO:0072321)4.06203313
13pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.04366167
14sperm-egg recognition (GO:0035036)4.00412483
15water-soluble vitamin biosynthetic process (GO:0042364)4.00392306
16maturation of SSU-rRNA (GO:0030490)3.93461032
17GTP biosynthetic process (GO:0006183)3.91319540
18acrosome reaction (GO:0007340)3.86602746
19sperm motility (GO:0030317)3.82826524
20axonemal dynein complex assembly (GO:0070286)3.81262528
21DNA replication initiation (GO:0006270)3.80704070
22spliceosomal snRNP assembly (GO:0000387)3.80222473
23binding of sperm to zona pellucida (GO:0007339)3.79138226
24fusion of sperm to egg plasma membrane (GO:0007342)3.75182392
25regulation of mitochondrial translation (GO:0070129)3.75130728
26pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.74296495
27guanosine-containing compound biosynthetic process (GO:1901070)3.73486907
28CTP metabolic process (GO:0046036)3.72557195
29CTP biosynthetic process (GO:0006241)3.72557195
30ribosomal small subunit biogenesis (GO:0042274)3.71612048
31respiratory electron transport chain (GO:0022904)3.71191028
32epithelial cilium movement (GO:0003351)3.70286448
33electron transport chain (GO:0022900)3.69114588
34telomere maintenance via semi-conservative replication (GO:0032201)3.67729710
35nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.66350869
36intracellular protein transmembrane import (GO:0044743)3.64736007
37viral transcription (GO:0019083)3.62840297
38exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.61441635
39L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.60230334
40cilium or flagellum-dependent cell motility (GO:0001539)3.58700757
41translational termination (GO:0006415)3.58158918
42protein-cofactor linkage (GO:0018065)3.57391747
43acrosome assembly (GO:0001675)3.56324371
44rRNA methylation (GO:0031167)3.52984043
45regulation of cilium movement (GO:0003352)3.52659356
46protein complex biogenesis (GO:0070271)3.50544689
47cell-cell recognition (GO:0009988)3.50381745
48ribosomal large subunit biogenesis (GO:0042273)3.48697885
49purine nucleobase biosynthetic process (GO:0009113)3.46720330
50protein targeting to mitochondrion (GO:0006626)3.45184220
51SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.44508644
52UTP biosynthetic process (GO:0006228)3.42590003
53ribosome assembly (GO:0042255)3.41451203
54cotranslational protein targeting to membrane (GO:0006613)3.40792942
55aldehyde catabolic process (GO:0046185)3.39984955
56mitochondrial respiratory chain complex assembly (GO:0033108)3.38592800
57pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.38073024
58protein localization to cilium (GO:0061512)3.36806345
59mitochondrial RNA metabolic process (GO:0000959)3.35762771
60protein targeting to ER (GO:0045047)3.33743427
61motile cilium assembly (GO:0044458)3.33493761
62DNA strand elongation involved in DNA replication (GO:0006271)3.33141786
63nucleobase biosynthetic process (GO:0046112)3.32881844
64mannosylation (GO:0097502)3.31274591
65respiratory chain complex IV assembly (GO:0008535)3.30465686
66tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.29682038
67RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.29682038
68protein neddylation (GO:0045116)3.28441793
69telomere maintenance via recombination (GO:0000722)3.27863298
70mitochondrial respiratory chain complex I assembly (GO:0032981)3.27840257
71NADH dehydrogenase complex assembly (GO:0010257)3.27840257
72mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.27840257
73sequestering of actin monomers (GO:0042989)3.26463404
74multicellular organism reproduction (GO:0032504)3.24018357
75anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.23821145
76establishment of protein localization to mitochondrion (GO:0072655)3.23536735
77DNA strand elongation (GO:0022616)3.23431315
78protein localization to endoplasmic reticulum (GO:0070972)3.23332385
79deoxyribose phosphate biosynthetic process (GO:0046385)3.22108085
802-deoxyribonucleotide biosynthetic process (GO:0009265)3.22108085
81tRNA processing (GO:0008033)3.21648723
82negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.21047280
83pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.20029450
84peptidyl-histidine modification (GO:0018202)3.18422691
85protein localization to mitochondrion (GO:0070585)3.18233936
86DNA replication checkpoint (GO:0000076)3.18147400
87translational elongation (GO:0006414)3.17729784
88CENP-A containing nucleosome assembly (GO:0034080)3.17698193
89establishment of protein localization to endoplasmic reticulum (GO:0072599)3.14434577
90DNA double-strand break processing (GO:0000729)3.13141229
91termination of RNA polymerase III transcription (GO:0006386)3.12267378
92transcription elongation from RNA polymerase III promoter (GO:0006385)3.12267378
93epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.11584329
94spermatid development (GO:0007286)3.09736293
95signal transduction involved in DNA integrity checkpoint (GO:0072401)3.09715764
96signal transduction involved in DNA damage checkpoint (GO:0072422)3.09715764
97cytochrome complex assembly (GO:0017004)3.07740740
98signal transduction involved in cell cycle checkpoint (GO:0072395)3.07616521
99chromatin remodeling at centromere (GO:0031055)3.07383030
100RNA capping (GO:0036260)3.07299221
1017-methylguanosine RNA capping (GO:0009452)3.07299221
102ribonucleoprotein complex biogenesis (GO:0022613)3.06749036
103pseudouridine synthesis (GO:0001522)3.05749654
104DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.05439944
105microtubule depolymerization (GO:0007019)3.04824573
106tRNA metabolic process (GO:0006399)3.02492828
107positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.02380007
108nucleotide-excision repair, DNA gap filling (GO:0006297)3.01950025
1097-methylguanosine mRNA capping (GO:0006370)3.01901012
110replication fork processing (GO:0031297)3.00312659
111rRNA processing (GO:0006364)2.99604432
112signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.99556029
113intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.99556029
114pyrimidine nucleotide biosynthetic process (GO:0006221)2.99188875
115signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.99136879
116signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.99136879
117signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.99136879
118negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.98132285
119negative regulation of ligase activity (GO:0051352)2.98132285
120cellular protein complex disassembly (GO:0043624)2.98046985
121deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.97899832
122regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.97822595
123purine nucleoside triphosphate biosynthetic process (GO:0009145)2.97738517
124translation (GO:0006412)2.97168652
125oxidative phosphorylation (GO:0006119)2.97160900
126regulation of cellular amino acid metabolic process (GO:0006521)2.97040936
127pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.96591735
128deoxyribonucleotide biosynthetic process (GO:0009263)2.94057509
129protein deneddylation (GO:0000338)2.93270228
130cellular component biogenesis (GO:0044085)2.93252672
131purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.93224336
132formation of translation preinitiation complex (GO:0001731)2.92985936
133RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.92442309
134antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.92136079
135ncRNA metabolic process (GO:0034660)2.91226234
136cilium movement (GO:0003341)2.90967590
137rRNA modification (GO:0000154)2.90882669
138amino acid salvage (GO:0043102)2.90844391
139L-methionine salvage (GO:0071267)2.90844391
140L-methionine biosynthetic process (GO:0071265)2.90844391
141plasma membrane fusion (GO:0045026)2.90321488
142DNA damage response, detection of DNA damage (GO:0042769)2.89966366
143cullin deneddylation (GO:0010388)2.89509078
144ATP biosynthetic process (GO:0006754)2.89455135
145positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.88966521
146positive regulation of ligase activity (GO:0051351)2.88649037
147histone mRNA metabolic process (GO:0008334)2.88589504
148tRNA modification (GO:0006400)2.88010616
149UTP metabolic process (GO:0046051)2.86905202
150nucleotide transmembrane transport (GO:1901679)2.85321189
151rRNA metabolic process (GO:0016072)2.84917295
152platelet dense granule organization (GO:0060155)2.84887737
153ncRNA processing (GO:0034470)2.81378886
154protein import into peroxisome matrix (GO:0016558)2.80245909
155DNA catabolic process, exonucleolytic (GO:0000738)2.78917659
156pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.74723714
157transcription from mitochondrial promoter (GO:0006390)2.73635035
158somatic diversification of immune receptors via somatic mutation (GO:0002566)2.72360261
159somatic hypermutation of immunoglobulin genes (GO:0016446)2.72360261
160intracellular protein transmembrane transport (GO:0065002)2.72103375

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.15411538
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.02575053
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.95482011
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.45530194
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.42643866
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.38285452
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.35836873
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.22070992
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.17212350
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.13111922
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.93697379
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.83051173
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.79215907
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.66044263
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.57517941
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.56611370
17ZNF274_21170338_ChIP-Seq_K562_Hela2.51709208
18SRF_21415370_ChIP-Seq_HL-1_Mouse2.46900915
19EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.46071332
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.42075522
21* VDR_23849224_ChIP-Seq_CD4+_Human2.39332738
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.32257235
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.28829690
24* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.27919519
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.24983812
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.21028896
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.18940445
28RBPJ_22232070_ChIP-Seq_NCS_Mouse2.17925554
29FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.04681386
30FOXP3_21729870_ChIP-Seq_TREG_Human2.02650492
31MYC_19079543_ChIP-ChIP_MESCs_Mouse2.01827047
32ELK1_19687146_ChIP-ChIP_HELA_Human1.99579940
33CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.98171777
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95400638
35THAP11_20581084_ChIP-Seq_MESCs_Mouse1.95298323
36VDR_22108803_ChIP-Seq_LS180_Human1.88222818
37DCP1A_22483619_ChIP-Seq_HELA_Human1.88206895
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.85612309
39* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.83276168
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.82965053
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.80976314
42NOTCH1_21737748_ChIP-Seq_TLL_Human1.80305001
43* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.74936477
44TTF2_22483619_ChIP-Seq_HELA_Human1.73184448
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.73144586
46XRN2_22483619_ChIP-Seq_HELA_Human1.70185296
47* GABP_19822575_ChIP-Seq_HepG2_Human1.69097665
48TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.68679562
49FLI1_27457419_Chip-Seq_LIVER_Mouse1.63311978
50PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62533553
51FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.61459094
52* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.60096777
53PCGF2_27294783_Chip-Seq_ESCs_Mouse1.56121201
54CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.52186382
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.46930468
56* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.45613454
57ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45474078
58SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.45064889
59* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.44882703
60FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43102280
61EWS_26573619_Chip-Seq_HEK293_Human1.37759572
62IRF1_19129219_ChIP-ChIP_H3396_Human1.31549671
63CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.29415634
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.28790720
65KDM5A_27292631_Chip-Seq_BREAST_Human1.26491668
66MYC_18940864_ChIP-ChIP_HL60_Human1.24432757
67SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20435229
68FUS_26573619_Chip-Seq_HEK293_Human1.17719922
69HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.14136613
70RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.13456912
71SPI1_23547873_ChIP-Seq_NB4_Human1.10718161
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09193268
73E2F1_21310950_ChIP-Seq_MCF-7_Human1.09087035
74GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.08315297
75EGR1_23403033_ChIP-Seq_LIVER_Mouse1.08070995
76POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07999565
77TP53_22573176_ChIP-Seq_HFKS_Human1.07856357
78DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05865725
79GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03958995
80SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03388629
81LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.01408761
82IGF1R_20145208_ChIP-Seq_DFB_Human0.98215950
83MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97807519
84SCL_19346495_ChIP-Seq_HPC-7_Human0.96453673
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95604053
86GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95534263
87CTCF_18555785_ChIP-Seq_MESCs_Mouse0.94249687
88NFE2_27457419_Chip-Seq_LIVER_Mouse0.93266533
89CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.92091900
90SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91270513
91MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.90804162
92FOXA1_25329375_ChIP-Seq_VCAP_Human0.89956460
93FOXA1_27270436_Chip-Seq_PROSTATE_Human0.89956460
94STAT4_19710469_ChIP-ChIP_TH1__Mouse0.89372453
95TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.89137784
96PADI4_21655091_ChIP-ChIP_MCF-7_Human0.88612921
97IRF8_21731497_ChIP-ChIP_J774_Mouse0.88357013
98CIITA_25753668_ChIP-Seq_RAJI_Human0.88158302
99POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87918991
100* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86772794
101ZFX_18555785_ChIP-Seq_MESCs_Mouse0.86001747
102AR_20517297_ChIP-Seq_VCAP_Human0.85735326
103ZFP57_27257070_Chip-Seq_ESCs_Mouse0.85489455
104GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.84149051
105NCOR_22424771_ChIP-Seq_293T_Human0.84072311
106LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.83829611
107ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.82619670
108CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82430403
109ELK1_22589737_ChIP-Seq_MCF10A_Human0.82189397
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.81943969
111NANOG_16153702_ChIP-ChIP_HESCs_Human0.81600446
112STAT3_18555785_Chip-Seq_ESCs_Mouse0.81563346
113CTBP1_25329375_ChIP-Seq_LNCAP_Human0.81209620
114NANOG_18555785_ChIP-Seq_MESCs_Mouse0.80472024
115SUZ12_27294783_Chip-Seq_NPCs_Mouse0.80430922
116BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.79444280
117RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.79114066
118PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.78164671
119TAL1_26923725_Chip-Seq_HPCs_Mouse0.77843004
120EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.77244802
121GATA3_21878914_ChIP-Seq_MCF-7_Human0.76860484
122POU3F2_20337985_ChIP-ChIP_501MEL_Human0.76565496
123FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76457599
124SOX2_16153702_ChIP-ChIP_HESCs_Human0.76271559
125CTBP2_25329375_ChIP-Seq_LNCAP_Human0.76263224
126EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.75481828
127POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.74651349
128KAP1_22055183_ChIP-Seq_ESCs_Mouse0.74533130
129NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.73172869
130P53_22387025_ChIP-Seq_ESCs_Mouse0.72965865
131IRF8_22096565_ChIP-ChIP_GC-B_Human0.72929229

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization5.05075842
2MP0003806_abnormal_nucleotide_metabolis3.57269143
3MP0009379_abnormal_foot_pigmentation3.15625763
4MP0008877_abnormal_DNA_methylation3.00686361
5MP0001986_abnormal_taste_sensitivity2.92949408
6MP0008058_abnormal_DNA_repair2.85490020
7MP0010094_abnormal_chromosome_stability2.67764908
8MP0002254_reproductive_system_inflammat2.63958792
9MP0008057_abnormal_DNA_replication2.59856191
10MP0001188_hyperpigmentation2.52125431
11MP0003693_abnormal_embryo_hatching2.50068269
12MP0008007_abnormal_cellular_replicative2.41484759
13MP0003195_calcinosis2.40161054
14MP0002396_abnormal_hematopoietic_system2.33233737
15MP0008875_abnormal_xenobiotic_pharmacok2.29337276
16MP0000372_irregular_coat_pigmentation2.27649374
17MP0001529_abnormal_vocalization2.16908384
18MP0003698_abnormal_male_reproductive2.14046435
19MP0001835_abnormal_antigen_presentation2.08520543
20MP0001929_abnormal_gametogenesis2.05586536
21MP0003787_abnormal_imprinting2.04483054
22MP0006292_abnormal_olfactory_placode1.99446350
23MP0002638_abnormal_pupillary_reflex1.99332741
24MP0003111_abnormal_nucleus_morphology1.97399555
25MP0004957_abnormal_blastocyst_morpholog1.95341813
26MP0005075_abnormal_melanosome_morpholog1.95075834
27MP0009697_abnormal_copulation1.94826529
28MP0005671_abnormal_response_to1.88515061
29MP0005423_abnormal_somatic_nervous1.88445161
30MP0003077_abnormal_cell_cycle1.88149194
31MP0006072_abnormal_retinal_apoptosis1.84565441
32MP0008872_abnormal_physiological_respon1.77997976
33MP0004147_increased_porphyrin_level1.74591813
34MP0002837_dystrophic_cardiac_calcinosis1.72272838
35MP0003786_premature_aging1.71883303
36MP0005174_abnormal_tail_pigmentation1.69886425
37MP0000015_abnormal_ear_pigmentation1.68217905
38MP0002210_abnormal_sex_determination1.65382398
39MP0002160_abnormal_reproductive_system1.61165400
40MP0008932_abnormal_embryonic_tissue1.56807548
41MP0005084_abnormal_gallbladder_morpholo1.52011517
42MP0001905_abnormal_dopamine_level1.45809461
43MP0010386_abnormal_urinary_bladder1.43192586
44MP0005397_hematopoietic_system_phenotyp1.43048388
45MP0001545_abnormal_hematopoietic_system1.43048388
46MP0002132_abnormal_respiratory_system1.42864247
47MP0003123_paternal_imprinting1.40677217
48MP0009785_altered_susceptibility_to1.39985276
49MP0002148_abnormal_hypersensitivity_rea1.37582421
50MP0003763_abnormal_thymus_physiology1.36305971
51MP0001764_abnormal_homeostasis1.35929241
52MP0002095_abnormal_skin_pigmentation1.34427217
53MP0002234_abnormal_pharynx_morphology1.34220494
54MP0003121_genomic_imprinting1.33837510
55MP0002736_abnormal_nociception_after1.33284409
56MP0001145_abnormal_male_reproductive1.32393789
57MP0003724_increased_susceptibility_to1.31874984
58MP0001984_abnormal_olfaction1.28774494
59MP0005332_abnormal_amino_acid1.27071653
60MP0005646_abnormal_pituitary_gland1.26183666
61MP0000490_abnormal_crypts_of1.25538665
62MP0004142_abnormal_muscle_tone1.25022186
63MP0005645_abnormal_hypothalamus_physiol1.24925179
64MP0005253_abnormal_eye_physiology1.24619990
65MP0004782_abnormal_surfactant_physiolog1.24422208
66MP0004808_abnormal_hematopoietic_stem1.20894724
67MP0004133_heterotaxia1.19802000
68MP0000653_abnormal_sex_gland1.17201897
69MP0002398_abnormal_bone_marrow1.16238701
70MP0002876_abnormal_thyroid_physiology1.14668331
71MP0000631_abnormal_neuroendocrine_gland1.12344997
72MP0006276_abnormal_autonomic_nervous1.12253023
73MP0009745_abnormal_behavioral_response1.11683250
74MP0003011_delayed_dark_adaptation1.11249155
75MP0002102_abnormal_ear_morphology1.11240952
76MP0009333_abnormal_splenocyte_physiolog1.09607567
77MP0003136_yellow_coat_color1.09291008
78MP0009046_muscle_twitch1.08208783
79MP0000358_abnormal_cell_content/1.06571684
80MP0003646_muscle_fatigue1.06425969
81MP0000689_abnormal_spleen_morphology1.05987716
82MP0006036_abnormal_mitochondrial_physio1.05981143
83MP0002161_abnormal_fertility/fecundity1.05465887
84MP0005025_abnormal_response_to1.05165169
85MP0001873_stomach_inflammation1.03818968
86MP0008789_abnormal_olfactory_epithelium1.03683731
87MP0002420_abnormal_adaptive_immunity1.03002656
88MP0002163_abnormal_gland_morphology1.02071721
89MP0001819_abnormal_immune_cell1.01137698
90MP0002723_abnormal_immune_serum1.00406508
91MP0003186_abnormal_redox_activity0.98409891
92MP0003315_abnormal_perineum_morphology0.97890506
93MP0005636_abnormal_mineral_homeostasis0.97838359
94MP0001919_abnormal_reproductive_system0.97325592
95MP0008995_early_reproductive_senescence0.96241574
96MP0002751_abnormal_autonomic_nervous0.95192403
97MP0002722_abnormal_immune_system0.94630541
98MP0000313_abnormal_cell_death0.94270782
99MP0005389_reproductive_system_phenotype0.93723044
100MP0005395_other_phenotype0.93050900
101MP0002452_abnormal_antigen_presenting0.92753612
102MP0002429_abnormal_blood_cell0.91762245
103MP0003866_abnormal_defecation0.91407912
104MP0002272_abnormal_nervous_system0.90839253
105MP0001968_abnormal_touch/_nociception0.90612997
106MP0005171_absent_coat_pigmentation0.90588555
107MP0005409_darkened_coat_color0.89771109
108MP0000716_abnormal_immune_system0.89347340
109MP0005085_abnormal_gallbladder_physiolo0.89052232
110MP0001800_abnormal_humoral_immune0.88772935
111MP0005551_abnormal_eye_electrophysiolog0.88125744
112MP0005379_endocrine/exocrine_gland_phen0.87418039
113MP0003943_abnormal_hepatobiliary_system0.86695039
114MP0005394_taste/olfaction_phenotype0.84423247
115MP0005499_abnormal_olfactory_system0.84423247
116MP0003718_maternal_effect0.84260956
117MP0003122_maternal_imprinting0.83843856
118MP0003567_abnormal_fetal_cardiomyocyte0.83735743
119MP0005000_abnormal_immune_tolerance0.83426849
120MP0000858_altered_metastatic_potential0.79149957
121MP0000703_abnormal_thymus_morphology0.78985462
122MP0003137_abnormal_impulse_conducting0.76994511
123MP0000516_abnormal_urinary_system0.76530619
124MP0005367_renal/urinary_system_phenotyp0.76530619
125MP0005464_abnormal_platelet_physiology0.76293740
126MP0002277_abnormal_respiratory_mucosa0.75645462
127MP0003950_abnormal_plasma_membrane0.74007881
128MP0000049_abnormal_middle_ear0.72589492
129MP0001853_heart_inflammation0.72510818
130MP0008873_increased_physiological_sensi0.72259180
131MP0003880_abnormal_central_pattern0.71577699
132MP0001293_anophthalmia0.71136793
133MP0001119_abnormal_female_reproductive0.69324785
134MP0002938_white_spotting0.68942463
135MP0002735_abnormal_chemical_nociception0.68170512
136MP0006035_abnormal_mitochondrial_morpho0.67990991
137MP0002019_abnormal_tumor_incidence0.66944012
138MP0001485_abnormal_pinna_reflex0.65905252
139MP0002733_abnormal_thermal_nociception0.65346225
140MP0004043_abnormal_pH_regulation0.65193513
141MP0005408_hypopigmentation0.63798237
142MP0006082_CNS_inflammation0.63059859
143MP0005195_abnormal_posterior_eye0.63049923
144MP0005360_urolithiasis0.62601893
145MP0005266_abnormal_metabolism0.61896761
146MP0001970_abnormal_pain_threshold0.59089260

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)4.91443177
2Absent/shortened dynein arms (HP:0200106)4.91443177
3Birth length less than 3rd percentile (HP:0003561)4.34253442
4Abnormal respiratory epithelium morphology (HP:0012253)4.32404001
5Abnormal respiratory motile cilium morphology (HP:0005938)4.32404001
6Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.12821179
7Acute necrotizing encephalopathy (HP:0006965)3.87508279
8Abnormal number of erythroid precursors (HP:0012131)3.84155624
9Abnormality of cells of the erythroid lineage (HP:0012130)3.74057637
10Abnormal hair whorl (HP:0010721)3.72230814
11Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.60687387
12Abnormality of alanine metabolism (HP:0010916)3.60687387
13Hyperalaninemia (HP:0003348)3.60687387
14Abnormal mitochondria in muscle tissue (HP:0008316)3.55249635
15Aplastic anemia (HP:0001915)3.53673222
16Mitochondrial inheritance (HP:0001427)3.48870621
17Abnormal respiratory motile cilium physiology (HP:0012261)3.42872705
18Abnormal ciliary motility (HP:0012262)3.37438489
19Type I transferrin isoform profile (HP:0003642)3.31776898
20Reticulocytopenia (HP:0001896)3.21304726
21Progressive macrocephaly (HP:0004481)3.09486037
22Medial flaring of the eyebrow (HP:0010747)3.09171236
23Cerebral edema (HP:0002181)3.08713302
24Hepatocellular necrosis (HP:0001404)3.05320049
25Increased CSF lactate (HP:0002490)3.01600981
26Acute encephalopathy (HP:0006846)2.99317139
27Methylmalonic acidemia (HP:0002912)2.92337241
283-Methylglutaconic aciduria (HP:0003535)2.90130423
29Increased hepatocellular lipid droplets (HP:0006565)2.80953531
30Rhinitis (HP:0012384)2.76898629
31Pallor (HP:0000980)2.74317093
32Pancreatic fibrosis (HP:0100732)2.72765825
33Increased serum pyruvate (HP:0003542)2.69773652
34Reduced antithrombin III activity (HP:0001976)2.67110264
35Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.65558850
36Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.63588066
37Decreased activity of mitochondrial respiratory chain (HP:0008972)2.63588066
38Methylmalonic aciduria (HP:0012120)2.63493722
39Generalized aminoaciduria (HP:0002909)2.62854488
40Pancytopenia (HP:0001876)2.57256200
41Thrombocytosis (HP:0001894)2.57139365
42True hermaphroditism (HP:0010459)2.56152330
43Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.55836237
44Abnormality of serum amino acid levels (HP:0003112)2.54883179
45Hepatic necrosis (HP:0002605)2.54483321
46Hyperglycinemia (HP:0002154)2.53300361
47Molar tooth sign on MRI (HP:0002419)2.51360655
48Abnormality of midbrain morphology (HP:0002418)2.51360655
49Lethargy (HP:0001254)2.50443353
50Exercise intolerance (HP:0003546)2.49567892
51Abnormality of the heme biosynthetic pathway (HP:0010472)2.48022134
52Nephronophthisis (HP:0000090)2.47495998
53Increased serum lactate (HP:0002151)2.46085529
54Congenital primary aphakia (HP:0007707)2.45978396
55Pancreatic cysts (HP:0001737)2.45197643
56Type 2 muscle fiber atrophy (HP:0003554)2.45176690
5711 pairs of ribs (HP:0000878)2.44483173
58Microvesicular hepatic steatosis (HP:0001414)2.42642557
59Abnormality of methionine metabolism (HP:0010901)2.40877169
60Nephrogenic diabetes insipidus (HP:0009806)2.40723743
61Abnormality of glycolysis (HP:0004366)2.38988039
62Optic disc pallor (HP:0000543)2.38931473
63Brushfield spots (HP:0001088)2.37279812
64Abnormal spermatogenesis (HP:0008669)2.35769787
65Macrocytic anemia (HP:0001972)2.35401624
66Renal Fanconi syndrome (HP:0001994)2.34698049
67Hypothermia (HP:0002045)2.34582727
68Gait imbalance (HP:0002141)2.34078515
69Type II lissencephaly (HP:0007260)2.31835132
70Abnormal protein glycosylation (HP:0012346)2.30795986
71Abnormal glycosylation (HP:0012345)2.30795986
72Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.30795986
73Abnormal protein N-linked glycosylation (HP:0012347)2.30795986
74CNS demyelination (HP:0007305)2.28977125
75Chromsome breakage (HP:0040012)2.27428071
76Congenital stationary night blindness (HP:0007642)2.25309047
77Chromosomal breakage induced by crosslinking agents (HP:0003221)2.24118856
78Lipid accumulation in hepatocytes (HP:0006561)2.23446095
79Abnormality of urine glucose concentration (HP:0011016)2.22949172
80Glycosuria (HP:0003076)2.22949172
81Leukodystrophy (HP:0002415)2.20317958
82Meckel diverticulum (HP:0002245)2.12679638
83Breast hypoplasia (HP:0003187)2.12149971
84Abnormality of aspartate family amino acid metabolism (HP:0010899)2.09262410
85Pendular nystagmus (HP:0012043)2.08237568
86Muscle fiber atrophy (HP:0100295)2.08197368
87Respiratory difficulties (HP:0002880)2.08010706
88Lactic acidosis (HP:0003128)2.06978826
89Unsteady gait (HP:0002317)2.06582567
90Severe visual impairment (HP:0001141)2.06046470
91Aplasia/Hypoplasia of the uvula (HP:0010293)2.05620634
92Abnormality of the ileum (HP:0001549)2.04972674
93Sclerocornea (HP:0000647)2.04547297
94Aplasia/Hypoplasia of the sacrum (HP:0008517)2.04120013
95Postaxial foot polydactyly (HP:0001830)2.03991995
96Exertional dyspnea (HP:0002875)2.03719543
97Hypoplasia of the pons (HP:0012110)2.02022874
98Myelodysplasia (HP:0002863)2.00836257
99Hyperglycinuria (HP:0003108)2.00403533
100Hypoplasia of the capital femoral epiphysis (HP:0003090)2.00223262
101Abnormality of glycine metabolism (HP:0010895)1.99546402
102Abnormality of serine family amino acid metabolism (HP:0010894)1.99546402
103Progressive microcephaly (HP:0000253)1.99275551
104Abnormality of the pons (HP:0007361)1.98652710
105Absent rod-and cone-mediated responses on ERG (HP:0007688)1.95092032
106Poor coordination (HP:0002370)1.92765882
107Chronic bronchitis (HP:0004469)1.91421170
108Nasal polyposis (HP:0100582)1.90701563
109Recurrent sinusitis (HP:0011108)1.89505554
110Infertility (HP:0000789)1.88742216
111Increased muscle lipid content (HP:0009058)1.88242552
112Oral leukoplakia (HP:0002745)1.87986509
113Abnormality of renal resorption (HP:0011038)1.87741301
114Abnormality of the prostate (HP:0008775)1.87680287
115Opisthotonus (HP:0002179)1.87510645
116Decreased electroretinogram (ERG) amplitude (HP:0000654)1.87209896
117Increased intramyocellular lipid droplets (HP:0012240)1.86907155
118Prostate neoplasm (HP:0100787)1.86809566
119Microretrognathia (HP:0000308)1.86677810
120Bronchiectasis (HP:0002110)1.85975578
121Abnormality of the preputium (HP:0100587)1.84754944
122Degeneration of anterior horn cells (HP:0002398)1.84505417
123Abnormality of the anterior horn cell (HP:0006802)1.84505417
124Cleft eyelid (HP:0000625)1.82767452
125Preaxial hand polydactyly (HP:0001177)1.80275205
126Redundant skin (HP:0001582)1.79003471
127Abnormality of the labia minora (HP:0012880)1.78922437
128Abnormality of sulfur amino acid metabolism (HP:0004339)1.78891125
129Congenital, generalized hypertrichosis (HP:0004540)1.78202012
130Abolished electroretinogram (ERG) (HP:0000550)1.77134862
131Median cleft lip (HP:0000161)1.76032104
132Cerebral hypomyelination (HP:0006808)1.75771948
133Respiratory failure (HP:0002878)1.75518183
134Dicarboxylic aciduria (HP:0003215)1.75352771
135Abnormality of dicarboxylic acid metabolism (HP:0010995)1.75352771
136Attenuation of retinal blood vessels (HP:0007843)1.74881342
137Renal cortical cysts (HP:0000803)1.74298585
138Epiphyseal stippling (HP:0010655)1.74122109
139Emotional lability (HP:0000712)1.73446285
140Patent foramen ovale (HP:0001655)1.73218304
141Abnormal rod and cone electroretinograms (HP:0008323)1.73029911
142Inability to walk (HP:0002540)1.72949293
143Progressive inability to walk (HP:0002505)1.71326512
144Colon cancer (HP:0003003)1.71006795
145Asplenia (HP:0001746)1.68159450
146Patellar aplasia (HP:0006443)1.67844514
147Delayed CNS myelination (HP:0002188)1.67506721
148Absent thumb (HP:0009777)1.65861844
149Supernumerary spleens (HP:0009799)1.65687442

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.16262502
2VRK24.15649144
3NME23.50969559
4CASK3.06051987
5BMPR1B3.01942430
6PDK42.56645743
7PDK32.56645743
8NUAK12.52133138
9EIF2AK12.48516741
10BUB12.36080543
11FRK2.34221640
12MAP3K122.28903120
13CCNB12.19187205
14BCKDK2.15283403
15CDK82.04525119
16WEE12.01958234
17MST42.00298520
18VRK11.99970388
19SRPK11.99672270
20TSSK61.98078439
21MAP4K21.96996741
22TLK11.92979949
23TNIK1.78879621
24WNK31.74271001
25BMPR21.71820018
26CDK191.69839212
27EIF2AK31.68046768
28NEK11.64186678
29TXK1.63042667
30PDK21.60326337
31MKNK11.58971251
32ADRBK21.58029112
33SIK31.49568243
34TRIM281.48953032
35MKNK21.43198645
36CSNK1G31.42468428
37PLK41.40423358
38TESK11.38142782
39TEC1.32967126
40DYRK21.32487287
41PIM21.30118809
42CDC71.30052226
43ERBB31.28607732
44PINK11.28189524
45TAF11.27133958
46IRAK41.26080688
47CSNK1G11.23666213
48ZAK1.22684689
49GRK71.22205202
50IRAK31.21514945
51INSRR1.18673291
52MAP2K71.18403547
53IRAK11.16122611
54CSNK1A1L1.13959164
55MUSK1.13276901
56CSNK1G21.10678336
57EIF2AK21.10052088
58KIT1.06422854
59BRSK21.00910050
60PLK10.99047505
61YES10.97565355
62MYLK0.96506629
63ATR0.96049887
64TAOK30.90702331
65AKT30.89058376
66MAPKAPK50.89055064
67PLK30.88744639
68WNK40.88621022
69PASK0.87393522
70MAPK130.85394719
71ACVR1B0.82608872
72MAPKAPK30.79466635
73CDK30.77876021
74DAPK10.75118600
75BTK0.72878598
76TIE10.70489770
77PRKCI0.69851661
78TGFBR10.68895937
79CHEK20.68836345
80CDK70.68510690
81LIMK10.67403853
82MAP2K60.66497402
83NEK20.64737315
84ADRBK10.63543070
85PRKCG0.63348011
86NME10.63330710
87CSNK2A10.63250453
88BRSK10.63157441
89BRAF0.62101337
90TESK20.60278869
91MAP3K40.59748198
92MAP4K10.59635177
93FLT30.59306962
94ABL20.59027640
95OXSR10.58517870
96CLK10.58296302
97RPS6KB10.57138679
98DYRK30.55245663
99AURKA0.53789433
100AURKB0.53617587
101SYK0.53592941
102SCYL20.52978829
103PIM10.50623032
104CSF1R0.49320217
105DAPK20.49074290
106CSNK2A20.48770335
107LYN0.48179642
108NLK0.47991894
109PLK20.47190644
110GRK10.46564139
111PHKG20.46517340
112PHKG10.46517340
113ERBB40.46205392
114NEK90.45818381
115IKBKE0.44491051
116ZAP700.43348172
117TTK0.43033324
118BLK0.42991611
119PKN10.41610853
120CSNK1A10.41580959
121DAPK30.41446921
122STK390.41367033
123PBK0.40421311
124LCK0.40055504
125NEK60.38649710
126KDR0.38301096
127IKBKB0.38245611
128FES0.38078642
129ALK0.37349720
130PNCK0.36451168
131PRKCE0.35895871
132RPS6KA40.34906049
133IRAK20.34346970
134ATM0.33808148
135RPS6KA50.33764217
136STK38L0.32358343
137CHEK10.31580396
138RPS6KB20.29976703
139PRKG20.27804650
140PRKCQ0.26971445
141MAP3K110.25964422

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.15351067
2Proteasome_Homo sapiens_hsa030503.93477885
3DNA replication_Homo sapiens_hsa030303.93137674
4Mismatch repair_Homo sapiens_hsa034303.47908420
5RNA polymerase_Homo sapiens_hsa030203.22020860
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.89422025
7Protein export_Homo sapiens_hsa030602.73694413
8Oxidative phosphorylation_Homo sapiens_hsa001902.69007057
9Pyrimidine metabolism_Homo sapiens_hsa002402.64632976
10Homologous recombination_Homo sapiens_hsa034402.50597524
11Base excision repair_Homo sapiens_hsa034102.47629487
12Nucleotide excision repair_Homo sapiens_hsa034202.41705984
13Basal transcription factors_Homo sapiens_hsa030222.35919906
14Parkinsons disease_Homo sapiens_hsa050122.32456740
15Spliceosome_Homo sapiens_hsa030402.22991092
16Fanconi anemia pathway_Homo sapiens_hsa034602.18815075
17Huntingtons disease_Homo sapiens_hsa050162.11072742
18RNA transport_Homo sapiens_hsa030131.89130501
19Non-homologous end-joining_Homo sapiens_hsa034501.88783897
20Purine metabolism_Homo sapiens_hsa002301.82423916
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.80234145
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.76891583
23Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.68667838
24Alzheimers disease_Homo sapiens_hsa050101.63388517
25RNA degradation_Homo sapiens_hsa030181.59711796
26Selenocompound metabolism_Homo sapiens_hsa004501.52551048
27Cell cycle_Homo sapiens_hsa041101.51281937
28Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.48952295
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.46042032
30Fatty acid elongation_Homo sapiens_hsa000621.42086699
31Propanoate metabolism_Homo sapiens_hsa006401.39944981
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.37762955
33Butanoate metabolism_Homo sapiens_hsa006501.34168857
34Peroxisome_Homo sapiens_hsa041461.33491175
35Sulfur metabolism_Homo sapiens_hsa009201.30284483
36SNARE interactions in vesicular transport_Homo sapiens_hsa041301.25797872
37One carbon pool by folate_Homo sapiens_hsa006701.19333274
38Phototransduction_Homo sapiens_hsa047441.10624757
39Collecting duct acid secretion_Homo sapiens_hsa049661.07424371
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06050463
41Primary immunodeficiency_Homo sapiens_hsa053401.06028951
42Nitrogen metabolism_Homo sapiens_hsa009101.03463812
43Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.01583398
44Tryptophan metabolism_Homo sapiens_hsa003800.98841893
45Primary bile acid biosynthesis_Homo sapiens_hsa001200.98512106
46Epstein-Barr virus infection_Homo sapiens_hsa051690.96856429
47Pentose and glucuronate interconversions_Homo sapiens_hsa000400.94244480
48Arachidonic acid metabolism_Homo sapiens_hsa005900.89301340
49Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88840449
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86427963
51mRNA surveillance pathway_Homo sapiens_hsa030150.84369231
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.83105256
53Steroid biosynthesis_Homo sapiens_hsa001000.82402948
54N-Glycan biosynthesis_Homo sapiens_hsa005100.82187469
55Chemical carcinogenesis_Homo sapiens_hsa052040.79907393
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.77784498
57Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.76585082
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73972044
59Intestinal immune network for IgA production_Homo sapiens_hsa046720.72690629
60Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.72579654
61Nicotine addiction_Homo sapiens_hsa050330.72426953
62Antigen processing and presentation_Homo sapiens_hsa046120.72186531
63Cardiac muscle contraction_Homo sapiens_hsa042600.72050414
64Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.72042779
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71688902
66Vibrio cholerae infection_Homo sapiens_hsa051100.71480415
67Allograft rejection_Homo sapiens_hsa053300.71397247
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70728261
69Maturity onset diabetes of the young_Homo sapiens_hsa049500.69543678
70Fatty acid degradation_Homo sapiens_hsa000710.68812959
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67366739
72Vitamin B6 metabolism_Homo sapiens_hsa007500.66977281
73Systemic lupus erythematosus_Homo sapiens_hsa053220.66827435
74Other glycan degradation_Homo sapiens_hsa005110.66004576
75Caffeine metabolism_Homo sapiens_hsa002320.65877818
76Fatty acid metabolism_Homo sapiens_hsa012120.65371742
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63511462
78Herpes simplex infection_Homo sapiens_hsa051680.63290722
79Measles_Homo sapiens_hsa051620.63147122
80Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62969445
81Pentose phosphate pathway_Homo sapiens_hsa000300.62566159
822-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.61255330
83Biosynthesis of amino acids_Homo sapiens_hsa012300.61241113
84Carbon metabolism_Homo sapiens_hsa012000.60524893
85Retinol metabolism_Homo sapiens_hsa008300.60354947
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.59779141
87Rheumatoid arthritis_Homo sapiens_hsa053230.59279904
88Hematopoietic cell lineage_Homo sapiens_hsa046400.58823997
89Autoimmune thyroid disease_Homo sapiens_hsa053200.58795640
90Folate biosynthesis_Homo sapiens_hsa007900.58391620
91Metabolic pathways_Homo sapiens_hsa011000.57455757
92p53 signaling pathway_Homo sapiens_hsa041150.55354520
93Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.54071169
94Taste transduction_Homo sapiens_hsa047420.53609191
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.52741291
96beta-Alanine metabolism_Homo sapiens_hsa004100.52361097
97Fructose and mannose metabolism_Homo sapiens_hsa000510.51929274
98Cyanoamino acid metabolism_Homo sapiens_hsa004600.51872862
99Regulation of autophagy_Homo sapiens_hsa041400.51230268
100Legionellosis_Homo sapiens_hsa051340.50917833
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48988876
102Asthma_Homo sapiens_hsa053100.48898951
103Vitamin digestion and absorption_Homo sapiens_hsa049770.48045505
104Arginine and proline metabolism_Homo sapiens_hsa003300.46432961
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45834441
106Synaptic vesicle cycle_Homo sapiens_hsa047210.44852202
107Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42963134
108Fat digestion and absorption_Homo sapiens_hsa049750.42368791
109Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42309170
110Tyrosine metabolism_Homo sapiens_hsa003500.42125196
111Sulfur relay system_Homo sapiens_hsa041220.39952055
112Glycosaminoglycan degradation_Homo sapiens_hsa005310.39435449
113Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39300581
114Phagosome_Homo sapiens_hsa041450.38863730
115Linoleic acid metabolism_Homo sapiens_hsa005910.38521957
116RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.37900816
117Glutathione metabolism_Homo sapiens_hsa004800.37799986
118Oocyte meiosis_Homo sapiens_hsa041140.37762795
119Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37057798
120Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.34893526
121Amphetamine addiction_Homo sapiens_hsa050310.34713325
122Pyruvate metabolism_Homo sapiens_hsa006200.34465464
123Sphingolipid metabolism_Homo sapiens_hsa006000.33055838
124alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31625456
125NF-kappa B signaling pathway_Homo sapiens_hsa040640.31516414
126Viral carcinogenesis_Homo sapiens_hsa052030.31386785
127Drug metabolism - other enzymes_Homo sapiens_hsa009830.31278624
128Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30737379
129Alcoholism_Homo sapiens_hsa050340.30540415
130Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.29698719
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.29581764
132Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.29035305
133Galactose metabolism_Homo sapiens_hsa000520.26093158
134Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.25586685
135Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.25400577
136Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.25117613
137Serotonergic synapse_Homo sapiens_hsa047260.24937458
138Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23805742
139Type I diabetes mellitus_Homo sapiens_hsa049400.22905273
140Graft-versus-host disease_Homo sapiens_hsa053320.21761528
141Olfactory transduction_Homo sapiens_hsa047400.17921688
142Influenza A_Homo sapiens_hsa051640.15807818
143Ether lipid metabolism_Homo sapiens_hsa005650.15571017

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