RABGAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)6.89241184
2postsynaptic membrane organization (GO:0001941)6.06962034
3presynaptic membrane organization (GO:0097090)5.85340766
4short-term memory (GO:0007614)5.30829632
5positive regulation of protein kinase C signaling (GO:0090037)4.62830268
6interkinetic nuclear migration (GO:0022027)4.39843432
7neuron cell-cell adhesion (GO:0007158)4.38959194
8righting reflex (GO:0060013)4.19400890
9eyelid development in camera-type eye (GO:0061029)4.04563561
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.03595251
11neuronal action potential propagation (GO:0019227)3.98350576
12protein localization to synapse (GO:0035418)3.92122108
13facial nerve structural organization (GO:0021612)3.70888359
14melanin metabolic process (GO:0006582)3.64804321
15regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.54922850
16melanin biosynthetic process (GO:0042438)3.54472656
17cranial nerve structural organization (GO:0021604)3.49575248
18positive regulation of synapse assembly (GO:0051965)3.48035907
19vocalization behavior (GO:0071625)3.44261776
20omega-hydroxylase P450 pathway (GO:0097267)3.40435092
21regulation of protein kinase A signaling (GO:0010738)3.38939208
22positive regulation of dendritic spine morphogenesis (GO:0061003)3.38235616
23negative regulation of keratinocyte proliferation (GO:0010839)3.34533365
24ionotropic glutamate receptor signaling pathway (GO:0035235)3.30240123
25cranial nerve morphogenesis (GO:0021602)3.26237619
26membrane assembly (GO:0071709)3.25620810
27positive regulation of dendritic spine development (GO:0060999)3.23820736
28regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.23292189
29negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)3.19739578
30regulation of synapse assembly (GO:0051963)3.12984825
31dendritic spine morphogenesis (GO:0060997)3.12829752
32negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.10375769
33regulation of pigment cell differentiation (GO:0050932)3.08772347
34regulation of timing of cell differentiation (GO:0048505)3.08097553
35limb bud formation (GO:0060174)3.07396420
36retina layer formation (GO:0010842)3.03016229
37protein heterotetramerization (GO:0051290)2.99634259
38secondary metabolite biosynthetic process (GO:0044550)2.99507290
39central nervous system myelination (GO:0022010)2.97930341
40axon ensheathment in central nervous system (GO:0032291)2.97930341
41neuron recognition (GO:0008038)2.95990663
42cerebral cortex radially oriented cell migration (GO:0021799)2.95827241
43positive regulation of membrane potential (GO:0045838)2.90906211
44negative regulation of execution phase of apoptosis (GO:1900118)2.90113916
45forebrain neuron differentiation (GO:0021879)2.89907567
46central nervous system neuron axonogenesis (GO:0021955)2.89725010
47glutamate receptor signaling pathway (GO:0007215)2.87964570
48regulation of glutamate receptor signaling pathway (GO:1900449)2.87576311
49regulation of respiratory system process (GO:0044065)2.86884559
50central nervous system projection neuron axonogenesis (GO:0021952)2.86589511
51anatomical structure arrangement (GO:0048532)2.86504472
52mesenchymal cell differentiation involved in renal system development (GO:2001012)2.85839587
53mesenchymal cell differentiation involved in kidney development (GO:0072161)2.85839587
54apical protein localization (GO:0045176)2.85618349
55regulation of development, heterochronic (GO:0040034)2.85136041
56establishment of nucleus localization (GO:0040023)2.83687627
57organ growth (GO:0035265)2.83055512
58peripheral nervous system axon ensheathment (GO:0032292)2.82096572
59myelination in peripheral nervous system (GO:0022011)2.82096572
60regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.81737816
61regulation of protein kinase C signaling (GO:0090036)2.79975769
62transmission of nerve impulse (GO:0019226)2.78420324
63sympathetic nervous system development (GO:0048485)2.77393903
64regulation of respiratory gaseous exchange (GO:0043576)2.74591105
65paraxial mesoderm development (GO:0048339)2.69779283
66cornea development in camera-type eye (GO:0061303)2.69275395
67positive regulation of meiosis (GO:0045836)2.68994249
68negative regulation of synaptic transmission, GABAergic (GO:0032229)2.68367062
69regulation of dendritic spine development (GO:0060998)2.67321393
70generation of neurons (GO:0048699)2.65682357
71metanephric nephron tubule development (GO:0072234)2.65280921
72metanephric tubule development (GO:0072170)2.65280921
73axonal fasciculation (GO:0007413)2.64214974
74positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.63504789
75regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.62147494
76neuronal stem cell maintenance (GO:0097150)2.60586313
77reflex (GO:0060004)2.59708052
78cytoskeletal anchoring at plasma membrane (GO:0007016)2.58194984
79camera-type eye morphogenesis (GO:0048593)2.57832773
80regulation of excitatory postsynaptic membrane potential (GO:0060079)2.56494911
81regulation of short-term neuronal synaptic plasticity (GO:0048172)2.56262321
82synaptic transmission, glutamatergic (GO:0035249)2.55440228
83mesonephros development (GO:0001823)2.54487619
84regulation of axon guidance (GO:1902667)2.53826526
85regulation of axon extension involved in axon guidance (GO:0048841)2.52613545
86startle response (GO:0001964)2.52383771
87positive regulation of meiotic cell cycle (GO:0051446)2.52204813
88negative regulation of neurotransmitter transport (GO:0051589)2.51898896
89suckling behavior (GO:0001967)2.50370857
90axon extension (GO:0048675)2.50213056
91nucleus localization (GO:0051647)2.49113735
92embryonic retina morphogenesis in camera-type eye (GO:0060059)2.49079706
93neuron remodeling (GO:0016322)2.48994825
94neurotransmitter-gated ion channel clustering (GO:0072578)2.48938538
95negative regulation of vascular permeability (GO:0043116)2.46597475
96metanephric epithelium development (GO:0072207)2.46345305
97nerve growth factor signaling pathway (GO:0038180)2.45724473
98appendage development (GO:0048736)2.45397072
99limb development (GO:0060173)2.45397072
100synaptic vesicle docking involved in exocytosis (GO:0016081)2.45062602
101positive regulation of synaptic transmission, GABAergic (GO:0032230)2.44550412
102regulation of dendritic spine morphogenesis (GO:0061001)2.44326507
103eye photoreceptor cell differentiation (GO:0001754)2.44112383
104photoreceptor cell differentiation (GO:0046530)2.44112383
105regulation of postsynaptic membrane potential (GO:0060078)2.43995446
106mechanosensory behavior (GO:0007638)2.43784357
107kidney mesenchyme development (GO:0072074)2.43256395
108synapse assembly (GO:0007416)2.43033426
109DNA methylation involved in gamete generation (GO:0043046)2.42887045
110neuron-neuron synaptic transmission (GO:0007270)2.42055965
111forebrain neuron development (GO:0021884)2.40901148
112gamma-aminobutyric acid signaling pathway (GO:0007214)2.39403513
113metanephric mesenchyme development (GO:0072075)2.39392803
114negative regulation of neurotransmitter secretion (GO:0046929)2.39338796
115regulation of synapse organization (GO:0050807)2.38806886
116auditory behavior (GO:0031223)2.38769681
117dendrite morphogenesis (GO:0048813)2.38615955
118neuron projection extension (GO:1990138)2.38194307
119asymmetric protein localization (GO:0008105)2.37497566
120layer formation in cerebral cortex (GO:0021819)2.32700823
121vesicle transport along microtubule (GO:0047496)2.31726858
122Golgi to endosome transport (GO:0006895)2.31478609
123myotube differentiation (GO:0014902)2.31328491
124cell migration in hindbrain (GO:0021535)2.29935595
125cell communication by electrical coupling (GO:0010644)2.27576811
126myoblast fusion (GO:0007520)2.27235971
127cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.26784402
128collagen fibril organization (GO:0030199)2.26501594
129pyrimidine nucleobase catabolic process (GO:0006208)2.26444952
130histone H3-K9 demethylation (GO:0033169)2.22750862
131developmental cell growth (GO:0048588)2.22740521
132astrocyte development (GO:0014002)2.22204091
133neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.21937716
134regulation of NFAT protein import into nucleus (GO:0051532)2.21257234
135insulin-like growth factor receptor signaling pathway (GO:0048009)2.20080019
136cerebellar granule cell differentiation (GO:0021707)2.18254082
137axon extension involved in axon guidance (GO:0048846)2.15834712
138neuron projection extension involved in neuron projection guidance (GO:1902284)2.15834712
139positive regulation of dendrite morphogenesis (GO:0050775)2.13452151
140chondrocyte development (GO:0002063)2.13097380
141cardiac myofibril assembly (GO:0055003)2.13068195
142cytoplasmic mRNA processing body assembly (GO:0033962)2.12543062
143synaptic vesicle maturation (GO:0016188)2.10970662
144organelle transport along microtubule (GO:0072384)2.09976755
145negative regulation of catenin import into nucleus (GO:0035414)2.09511100
146neuromuscular junction development (GO:0007528)2.09254983
147glutamate secretion (GO:0014047)2.07293362
148calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.05244649
149cerebral cortex development (GO:0021987)2.04846474
150stress granule assembly (GO:0034063)2.04479747
151regulation of synaptic vesicle exocytosis (GO:2000300)2.04351025
152cellular potassium ion homeostasis (GO:0030007)2.02182239
153morphogenesis of an epithelial sheet (GO:0002011)2.02018436
154innervation (GO:0060384)2.01461254
155cell communication involved in cardiac conduction (GO:0086065)2.01311996
156cellular response to catecholamine stimulus (GO:0071870)2.00529690
157cellular response to monoamine stimulus (GO:0071868)2.00529690
158sodium ion export (GO:0071436)1.99722824
159hippo signaling (GO:0035329)1.99420178
160regulation of neuronal synaptic plasticity (GO:0048168)1.99290073
161peptidyl-lysine dimethylation (GO:0018027)1.99115388
162planar cell polarity pathway involved in neural tube closure (GO:0090179)1.99062253
163establishment of spindle orientation (GO:0051294)1.98689698
164lateral sprouting from an epithelium (GO:0060601)1.98651319
165neuronal ion channel clustering (GO:0045161)1.97936014
166regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)1.97058037
167cerebral cortex cell migration (GO:0021795)1.96114144
168negative regulation of cytosolic calcium ion concentration (GO:0051481)1.95703448
169regulation of neuron migration (GO:2001222)1.94908150
170lens morphogenesis in camera-type eye (GO:0002089)1.94289240
171negative chemotaxis (GO:0050919)1.93660064
172positive regulation of calcium ion-dependent exocytosis (GO:0045956)1.93571675
173forebrain development (GO:0030900)1.93568691
174eye morphogenesis (GO:0048592)1.93144262
175synapse organization (GO:0050808)1.92980343

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.82846741
2GBX2_23144817_ChIP-Seq_PC3_Human3.67775808
3JARID2_20064375_ChIP-Seq_MESCs_Mouse2.88972764
4TAF15_26573619_Chip-Seq_HEK293_Human2.59789866
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.58302753
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.46399126
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.40550961
8EED_16625203_ChIP-ChIP_MESCs_Mouse2.39789976
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.27340916
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26480178
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.24081974
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.24081974
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.15642787
14BMI1_23680149_ChIP-Seq_NPCS_Mouse2.15176852
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14649236
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.14303993
17CBX2_27304074_Chip-Seq_ESCs_Mouse2.08466880
18FLI1_27457419_Chip-Seq_LIVER_Mouse2.08429452
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.08285626
20AR_21572438_ChIP-Seq_LNCaP_Human2.05232943
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.01923632
22PCGF2_27294783_Chip-Seq_ESCs_Mouse2.00065997
23PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.98335130
24POU3F2_20337985_ChIP-ChIP_501MEL_Human1.90775344
25RNF2_27304074_Chip-Seq_ESCs_Mouse1.89035856
26RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.88462296
27PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.87351274
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.86706122
29RNF2_27304074_Chip-Seq_NSC_Mouse1.84175065
30EZH2_27294783_Chip-Seq_ESCs_Mouse1.81205279
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79072472
32EP300_21415370_ChIP-Seq_HL-1_Mouse1.75922420
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74523031
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.73432077
35ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.73057474
36IGF1R_20145208_ChIP-Seq_DFB_Human1.71987785
37ESR1_20079471_ChIP-ChIP_T-47D_Human1.71107961
38P300_19829295_ChIP-Seq_ESCs_Human1.70381116
39SMAD4_21799915_ChIP-Seq_A2780_Human1.67563394
40FUS_26573619_Chip-Seq_HEK293_Human1.66779875
41SUZ12_27294783_Chip-Seq_ESCs_Mouse1.66557609
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.65541817
43SUZ12_27294783_Chip-Seq_NPCs_Mouse1.64910457
44MTF2_20144788_ChIP-Seq_MESCs_Mouse1.63582008
45SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.63069041
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.62570232
47CTNNB1_20460455_ChIP-Seq_HCT116_Human1.62202322
48SALL1_21062744_ChIP-ChIP_HESCs_Human1.60883096
49EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.60385548
50SMAD_19615063_ChIP-ChIP_OVARY_Human1.58040225
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.57806198
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.56773921
53SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.55744536
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.55510917
55NANOG_18555785_Chip-Seq_ESCs_Mouse1.55202605
56TP53_16413492_ChIP-PET_HCT116_Human1.54868967
57TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52845711
58NFE2_27457419_Chip-Seq_LIVER_Mouse1.51543867
59YAP1_20516196_ChIP-Seq_MESCs_Mouse1.50659936
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48683939
61WT1_19549856_ChIP-ChIP_CCG9911_Human1.47758632
62ER_23166858_ChIP-Seq_MCF-7_Human1.47474703
63TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.46431101
64NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.46421167
65NRF2_20460467_ChIP-Seq_MEFs_Mouse1.46421167
66TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.45435935
67SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.44197493
68OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43406576
69E2F1_18555785_Chip-Seq_ESCs_Mouse1.42665209
70EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.42564025
71WT1_25993318_ChIP-Seq_PODOCYTE_Human1.41628603
72AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.40049755
73TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36695711
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35183468
75SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34929878
76PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.34760342
77P53_22387025_ChIP-Seq_ESCs_Mouse1.34525071
78* STAT3_23295773_ChIP-Seq_U87_Human1.33107279
79ISL1_27105846_Chip-Seq_CPCs_Mouse1.32838911
80WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.32632423
81PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32273818
82TP53_18474530_ChIP-ChIP_U2OS_Human1.31795907
83SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.31443690
84P300_18555785_Chip-Seq_ESCs_Mouse1.31427655
85TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31282510
86EZH2_27294783_Chip-Seq_NPCs_Mouse1.31216366
87REST_21632747_ChIP-Seq_MESCs_Mouse1.30735875
88RUNX2_22187159_ChIP-Seq_PCA_Human1.28963062
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.28894880
90* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.27119611
91BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.26502665
92STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.26448824
93* TCF4_23295773_ChIP-Seq_U87_Human1.25499940
94SUZ12_18555785_Chip-Seq_ESCs_Mouse1.25338511
95CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.24252675
96CMYC_18555785_Chip-Seq_ESCs_Mouse1.23383923
97ESR2_21235772_ChIP-Seq_MCF-7_Human1.22838705
98TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.21737533
99ZNF217_24962896_ChIP-Seq_MCF-7_Human1.21725263
100SOX9_24532713_ChIP-Seq_HFSC_Mouse1.21332357
101* SOX2_21211035_ChIP-Seq_LN229_Gbm1.20599759
102FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19357469
103AR_19668381_ChIP-Seq_PC3_Human1.18472092
104NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18416190
105* NMYC_18555785_Chip-Seq_ESCs_Mouse1.18362254
106RING1B_27294783_Chip-Seq_NPCs_Mouse1.18306162
107RBPJ_22232070_ChIP-Seq_NCS_Mouse1.17510109
108LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16881679
109KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.16431335
110KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.16431335
111KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.16431335
112SOX2_18555785_Chip-Seq_ESCs_Mouse1.16142034
113UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16054006
114DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15765309
115TRIM28_21343339_ChIP-Seq_HEK293_Human1.14081863
116STAT3_18555785_Chip-Seq_ESCs_Mouse1.13833579
117RING1B_27294783_Chip-Seq_ESCs_Mouse1.12772108
118IRF1_19129219_ChIP-ChIP_H3396_Human1.12290107
119CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.11577878
120MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11370088
121ARNT_22903824_ChIP-Seq_MCF-7_Human1.10899707
122* AR_25329375_ChIP-Seq_VCAP_Human1.10825213
123ZNF274_21170338_ChIP-Seq_K562_Hela1.10791305
124TBX3_20139965_ChIP-Seq_MESCs_Mouse1.09444302
125AHR_22903824_ChIP-Seq_MCF-7_Human1.09133737
126KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08805260
127TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08763567
128POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08763567
129* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08704053
130TBX3_20139965_ChIP-Seq_ESCs_Mouse1.08673382
131CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08206419
132HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08137149
133DROSHA_22980978_ChIP-Seq_HELA_Human1.07787116
134NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07719486
135CJUN_26792858_Chip-Seq_BT549_Human1.07713240
136EWS_26573619_Chip-Seq_HEK293_Human1.07013867
137NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.05366548

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color6.42462811
2MP0001188_hyperpigmentation5.31220057
3MP0005409_darkened_coat_color5.17437982
4MP0003880_abnormal_central_pattern3.27831742
5MP0009379_abnormal_foot_pigmentation3.22857939
6MP0004381_abnormal_hair_follicle3.00196187
7MP0006292_abnormal_olfactory_placode2.78906303
8MP0009780_abnormal_chondrocyte_physiolo2.54322482
9MP0008438_abnormal_cutaneous_collagen2.44105806
10MP0003705_abnormal_hypodermis_morpholog2.38514425
11MP0005275_abnormal_skin_tensile2.33058498
12MP0000015_abnormal_ear_pigmentation2.28310981
13MP0004859_abnormal_synaptic_plasticity2.12763479
14MP0005503_abnormal_tendon_morphology2.06425655
15MP0000566_synostosis2.01165257
16MP0005174_abnormal_tail_pigmentation1.99715560
17MP0000778_abnormal_nervous_system1.94784904
18MP0001968_abnormal_touch/_nociception1.91964231
19MP0002102_abnormal_ear_morphology1.90606483
20MP0001486_abnormal_startle_reflex1.79939836
21MP0005171_absent_coat_pigmentation1.78224993
22MP0004270_analgesia1.76259001
23MP0003635_abnormal_synaptic_transmissio1.74994823
24MP0002177_abnormal_outer_ear1.68575308
25MP0009046_muscle_twitch1.65134152
26MP0001958_emphysema1.64019513
27MP0009745_abnormal_behavioral_response1.59442360
28MP0006276_abnormal_autonomic_nervous1.57706333
29MP0002751_abnormal_autonomic_nervous1.57180348
30MP0003938_abnormal_ear_development1.52545208
31MP0002734_abnormal_mechanical_nocicepti1.51317995
32MP0000534_abnormal_ureter_morphology1.50182715
33MP0003937_abnormal_limbs/digits/tail_de1.49787861
34MP0010234_abnormal_vibrissa_follicle1.46519563
35MP0004742_abnormal_vestibular_system1.45933077
36MP0003315_abnormal_perineum_morphology1.44555408
37MP0002067_abnormal_sensory_capabilities1.43999663
38MP0002249_abnormal_larynx_morphology1.42493749
39MP0002108_abnormal_muscle_morphology1.41596409
40MP0004142_abnormal_muscle_tone1.39581570
41MP0000049_abnormal_middle_ear1.39401411
42MP0000631_abnormal_neuroendocrine_gland1.37417998
43MP0002272_abnormal_nervous_system1.35192211
44MP0002638_abnormal_pupillary_reflex1.34785493
45MP0002064_seizures1.33912116
46MP0002557_abnormal_social/conspecific_i1.33322463
47MP0010368_abnormal_lymphatic_system1.33016549
48MP0000537_abnormal_urethra_morphology1.28132966
49MP0003890_abnormal_embryonic-extraembry1.26392274
50MP0001299_abnormal_eye_distance/1.25617367
51MP0003385_abnormal_body_wall1.25570081
52MP0003942_abnormal_urinary_system1.24982075
53MP0002184_abnormal_innervation1.24707177
54MP0002572_abnormal_emotion/affect_behav1.22873679
55MP0005423_abnormal_somatic_nervous1.22040432
56MP0004084_abnormal_cardiac_muscle1.21798448
57MP0010678_abnormal_skin_adnexa1.21666604
58MP0005248_abnormal_Harderian_gland1.21615718
59MP0001879_abnormal_lymphatic_vessel1.20552669
60MP0000383_abnormal_hair_follicle1.20223177
61MP0002277_abnormal_respiratory_mucosa1.19030314
62MP0001346_abnormal_lacrimal_gland1.18646205
63MP0000751_myopathy1.17551594
64MP0002063_abnormal_learning/memory/cond1.17524017
65MP0010030_abnormal_orbit_morphology1.16414860
66MP0000462_abnormal_digestive_system1.14021614
67MP0002009_preneoplasia1.13869406
68MP0009250_abnormal_appendicular_skeleto1.13318289
69MP0009384_cardiac_valve_regurgitation1.13158090
70MP0006072_abnormal_retinal_apoptosis1.12412943
71MP0002095_abnormal_skin_pigmentation1.10179703
72MP0001970_abnormal_pain_threshold1.09781770
73MP0000026_abnormal_inner_ear1.09542606
74MP0000733_abnormal_muscle_development1.08191008
75MP0002896_abnormal_bone_mineralization1.07057555
76MP0004145_abnormal_muscle_electrophysio1.05873894
77MP0001984_abnormal_olfaction1.04563095
78MP0003121_genomic_imprinting1.04332041
79MP0005257_abnormal_intraocular_pressure1.03678041
80MP0001286_abnormal_eye_development1.00732759
81MP0001177_atelectasis1.00536577
82MP0000579_abnormal_nail_morphology1.00463668
83MP0004811_abnormal_neuron_physiology0.99522704
84MP0003941_abnormal_skin_development0.99422069
85MP0001340_abnormal_eyelid_morphology0.99334443
86MP0003755_abnormal_palate_morphology0.98360790
87MP0002160_abnormal_reproductive_system0.97552781
88MP0003566_abnormal_cell_adhesion0.96939704
89MP0002882_abnormal_neuron_morphology0.96588543
90MP0004036_abnormal_muscle_relaxation0.96193034
91MP0001963_abnormal_hearing_physiology0.95914312
92MP0003634_abnormal_glial_cell0.94484693
93MP0005076_abnormal_cell_differentiation0.93701211
94MP0002876_abnormal_thyroid_physiology0.92869512
95MP0003787_abnormal_imprinting0.92636911
96MP0001440_abnormal_grooming_behavior0.92587104
97MP0002752_abnormal_somatic_nervous0.92493014
98MP0003950_abnormal_plasma_membrane0.92409779
99MP0000613_abnormal_salivary_gland0.91963602
100MP0003935_abnormal_craniofacial_develop0.91817081
101MP0003091_abnormal_cell_migration0.90768164
102MP0000955_abnormal_spinal_cord0.90725840
103MP0001986_abnormal_taste_sensitivity0.90245992
104MP0002938_white_spotting0.89066787
105MP0002697_abnormal_eye_size0.88660543
106MP0002733_abnormal_thermal_nociception0.88223020
107MP0004885_abnormal_endolymph0.86665710
108MP0002152_abnormal_brain_morphology0.86015467
109MP0008569_lethality_at_weaning0.85161810
110MP0002735_abnormal_chemical_nociception0.84934361
111MP0003122_maternal_imprinting0.84931573
112MP0000427_abnormal_hair_cycle0.84916344
113MP0004130_abnormal_muscle_cell0.84600356
114MP0000467_abnormal_esophagus_morphology0.84279126
115MP0001502_abnormal_circadian_rhythm0.84089034
116MP0000762_abnormal_tongue_morphology0.84077479
117MP0001485_abnormal_pinna_reflex0.83410708
118MP0004858_abnormal_nervous_system0.83016630
119MP0004087_abnormal_muscle_fiber0.80424765
120MP0002081_perinatal_lethality0.80410636
121MP0003115_abnormal_respiratory_system0.80298853
122MP0003861_abnormal_nervous_system0.80273024
123MP0006138_congestive_heart_failure0.80101711
124MP0005551_abnormal_eye_electrophysiolog0.79899895
125MP0010352_gastrointestinal_tract_polyps0.79488726
126MP0005508_abnormal_skeleton_morphology0.79483885
127MP0003279_aneurysm0.79234608
128MP0005620_abnormal_muscle_contractility0.79163061
129MP0005595_abnormal_vascular_smooth0.78467116
130MP0004233_abnormal_muscle_weight0.77373823
131MP0002822_catalepsy0.77251707
132MP0003329_amyloid_beta_deposits0.77219752
133MP0005623_abnormal_meninges_morphology0.76044036
134MP0001919_abnormal_reproductive_system0.75136105
135MP0002909_abnormal_adrenal_gland0.74598622
136MP0000428_abnormal_craniofacial_morphol0.74547817
137MP0002233_abnormal_nose_morphology0.74023306
138MP0001905_abnormal_dopamine_level0.73630652
139MP0005645_abnormal_hypothalamus_physiol0.73299200
140MP0005187_abnormal_penis_morphology0.73277579
141MP0002114_abnormal_axial_skeleton0.73096555
142MP0009703_decreased_birth_body0.73057256
143MP0009053_abnormal_anal_canal0.71977711
144MP0004484_altered_response_of0.71367811
145MP0004272_abnormal_basement_membrane0.70726055
146MP0002116_abnormal_craniofacial_bone0.70319638
147MP0000432_abnormal_head_morphology0.70094121
148MP0000569_abnormal_digit_pigmentation0.68129028
149MP0000681_abnormal_thyroid_gland0.66215378
150MP0005386_behavior/neurological_phenoty0.66139701
151MP0004924_abnormal_behavior0.66139701
152MP0002066_abnormal_motor_capabilities/c0.64742078
153MP0001661_extended_life_span0.63388977

Predicted human phenotypes

RankGene SetZ-score
1Abnormal sex determination (HP:0012244)6.83739289
2Sex reversal (HP:0012245)6.83739289
3Abnormality of the axillary hair (HP:0100134)5.65945090
4Abnormality of secondary sexual hair (HP:0009888)5.65945090
5Focal motor seizures (HP:0011153)4.48442613
6Abnormal biliary tract physiology (HP:0012439)3.52029535
7Bile duct proliferation (HP:0001408)3.52029535
8Alacrima (HP:0000522)3.46775111
9Obstructive sleep apnea (HP:0002870)3.46501750
10Febrile seizures (HP:0002373)3.32260841
11Septo-optic dysplasia (HP:0100842)3.26160667
12Testicular neoplasm (HP:0010788)3.18522945
13Decreased lacrimation (HP:0000633)3.14298833
14Vascular tortuosity (HP:0004948)3.09529369
15Optic nerve hypoplasia (HP:0000609)3.07803147
16Gonadal dysgenesis (HP:0000133)3.03751974
17Arterial tortuosity (HP:0005116)3.00486997
18Absent speech (HP:0001344)2.95954620
19Germ cell neoplasia (HP:0100728)2.89106135
20Neonatal short-limb short stature (HP:0008921)2.71185459
21Papillary thyroid carcinoma (HP:0002895)2.70974041
22Cutaneous finger syndactyly (HP:0010554)2.65632020
23Aortic aneurysm (HP:0004942)2.64666288
24Overgrowth (HP:0001548)2.63105689
25Protrusio acetabuli (HP:0003179)2.63103975
26Aortic dissection (HP:0002647)2.62356671
27Abnormality of the ischium (HP:0003174)2.59483530
28Gaze-evoked nystagmus (HP:0000640)2.58911752
29Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.53993247
30Absent septum pellucidum (HP:0001331)2.53987665
31Broad-based gait (HP:0002136)2.51987365
32Dynein arm defect of respiratory motile cilia (HP:0012255)2.49935206
33Absent/shortened dynein arms (HP:0200106)2.49935206
34Male pseudohermaphroditism (HP:0000037)2.49307721
35Abnormality of the septum pellucidum (HP:0007375)2.48666844
36Progressive cerebellar ataxia (HP:0002073)2.44540705
37Sleep apnea (HP:0010535)2.41423021
38Thyroid-stimulating hormone excess (HP:0002925)2.40374356
39Nonprogressive disorder (HP:0003680)2.35711860
40Focal seizures (HP:0007359)2.32914168
41Shallow orbits (HP:0000586)2.31031127
42Nephronophthisis (HP:0000090)2.30561531
43Vertebral arch anomaly (HP:0008438)2.29687464
44Ulnar claw (HP:0001178)2.28909587
45Sensory axonal neuropathy (HP:0003390)2.27034455
46Absent frontal sinuses (HP:0002688)2.25350360
47Aplasia/Hypoplasia of the tibia (HP:0005772)2.24782436
48Split foot (HP:0001839)2.23970605
49Stage 5 chronic kidney disease (HP:0003774)2.23352416
50Attenuation of retinal blood vessels (HP:0007843)2.23156576
51Abnormal ciliary motility (HP:0012262)2.22959307
52Heterotopia (HP:0002282)2.20620707
53Turricephaly (HP:0000262)2.20164758
54Short tibia (HP:0005736)2.19835501
55Premature rupture of membranes (HP:0001788)2.19051960
56Cutaneous syndactyly (HP:0012725)2.18436834
57Wide anterior fontanel (HP:0000260)2.16951481
58Atonic seizures (HP:0010819)2.15988861
59Neoplasm of the heart (HP:0100544)2.15843716
60Excessive salivation (HP:0003781)2.14949462
61Drooling (HP:0002307)2.14949462
62Epileptic encephalopathy (HP:0200134)2.14635228
63Bladder diverticulum (HP:0000015)2.13217221
64Soft skin (HP:0000977)2.11501395
65Supernumerary ribs (HP:0005815)2.08814554
66Generalized myoclonic seizures (HP:0002123)2.08057897
67Mitral valve prolapse (HP:0001634)2.06765452
68Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.06323719
69Hypoplastic ischia (HP:0003175)2.05441530
70Hypoplasia of the iris (HP:0007676)2.01929098
71Chin dimple (HP:0010751)2.01855977
72Dysmetria (HP:0001310)2.00733990
73Midline defect of the nose (HP:0004122)2.00119492
74Broad metatarsal (HP:0001783)1.99029515
75Agitation (HP:0000713)1.97611648
76Cerebral aneurysm (HP:0004944)1.97444107
77Hypothermia (HP:0002045)1.95742947
78Infantile muscular hypotonia (HP:0008947)1.95561295
79Supernumerary bones of the axial skeleton (HP:0009144)1.94268223
80Mild short stature (HP:0003502)1.93611958
81Limited hip movement (HP:0008800)1.93237864
82Action tremor (HP:0002345)1.92231154
83Abnormality of the renal medulla (HP:0100957)1.91621103
84Fibular aplasia (HP:0002990)1.91247886
85Bowel diverticulosis (HP:0005222)1.90966068
86Laryngomalacia (HP:0001601)1.90928155
87Optic disc pallor (HP:0000543)1.89705795
88Morphological abnormality of the middle ear (HP:0008609)1.88734189
89Tracheomalacia (HP:0002779)1.88482937
90Abnormal respiratory motile cilium physiology (HP:0012261)1.85896836
91Fair hair (HP:0002286)1.85824389
92Cubitus valgus (HP:0002967)1.85459037
93Abnormality of the nasolacrimal system (HP:0000614)1.85441629
94Renovascular hypertension (HP:0100817)1.84670351
95Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.84102021
96Esotropia (HP:0000565)1.83756836
97Hyporeflexia of lower limbs (HP:0002600)1.83669295
98Truncal obesity (HP:0001956)1.83276012
99Short chin (HP:0000331)1.82327030
100Bradycardia (HP:0001662)1.80990528
101Genetic anticipation (HP:0003743)1.80430235
102Intellectual disability, moderate (HP:0002342)1.80240254
103Scanning speech (HP:0002168)1.79910451
104Narrow palate (HP:0000189)1.79885290
105Hyperthyroidism (HP:0000836)1.78881780
106Short 4th metacarpal (HP:0010044)1.77929069
107Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.77929069
108Macroorchidism (HP:0000053)1.77141499
109Supernumerary spleens (HP:0009799)1.76551732
110Concave nail (HP:0001598)1.76481535
111Bronchomalacia (HP:0002780)1.75325399
112Hypophosphatemic rickets (HP:0004912)1.75193850
113Aplasia cutis congenita (HP:0001057)1.75015340
114Abnormal respiratory motile cilium morphology (HP:0005938)1.73277237
115Abnormal respiratory epithelium morphology (HP:0012253)1.73277237
116Abnormality of the clitoris (HP:0000056)1.72060120
117Atelectasis (HP:0100750)1.72053968
118Abnormality of incisor morphology (HP:0011063)1.71556796
119Aplasia/hypoplasia of the uterus (HP:0008684)1.71234502
120Clitoromegaly (HP:0000057)1.70661667
121Myokymia (HP:0002411)1.70628306
122Nasolacrimal duct obstruction (HP:0000579)1.68860886
123Pulmonic stenosis (HP:0001642)1.67537741
124Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.66835595
125Blue irides (HP:0000635)1.66392274
126Buphthalmos (HP:0000557)1.66385772
127Abnormality of dentin (HP:0010299)1.66090835
128Hammertoe (HP:0001765)1.65643175
129Aplasia involving bones of the extremities (HP:0009825)1.65178902
130Aplasia involving bones of the upper limbs (HP:0009823)1.65178902
131Aplasia of the phalanges of the hand (HP:0009802)1.65178902
132Abnormality of the lacrimal duct (HP:0011481)1.65092955
133Generalized hypopigmentation of hair (HP:0011358)1.64650909
134Submucous cleft hard palate (HP:0000176)1.63586779
135Limb dystonia (HP:0002451)1.62574135
136Hyperextensible skin (HP:0000974)1.60929608
137Abnormality of salivation (HP:0100755)1.60874562
138True hermaphroditism (HP:0010459)1.60844830
139Hyperacusis (HP:0010780)1.59807550
140Steppage gait (HP:0003376)1.59391488
141Abnormality of the nasal septum (HP:0000419)1.58991924
142Bundle branch block (HP:0011710)1.58747532
143Maternal diabetes (HP:0009800)1.58108179
144Coronal craniosynostosis (HP:0004440)1.57967434
145Abnormality of the pulmonary veins (HP:0011718)1.57564559
146Tibial bowing (HP:0002982)1.57061278
147Abnormal hair whorl (HP:0010721)1.56779755
148Mitral regurgitation (HP:0001653)1.56153990
149Dysmetric saccades (HP:0000641)1.55338200
150Neurofibrillary tangles (HP:0002185)1.54678775
151Atrophic scars (HP:0001075)1.53924393
152Urinary bladder sphincter dysfunction (HP:0002839)1.53705890
153Wormian bones (HP:0002645)1.53290020
154Parakeratosis (HP:0001036)1.53237715
155Aqueductal stenosis (HP:0002410)1.53088851
156Absent eyebrow (HP:0002223)1.52776359
157Abnormality of the distal phalanx of the thumb (HP:0009617)1.51914519
158Insidious onset (HP:0003587)1.51634704
159Termporal pattern (HP:0011008)1.51634704
160Fragile skin (HP:0001030)1.50834342
161Omphalocele (HP:0001539)1.50620284
162Abnormality of the left ventricular outflow tract (HP:0011103)1.49767077
163Subaortic stenosis (HP:0001682)1.49767077
164Type 1 muscle fiber predominance (HP:0003803)1.48945018
165Difficulty running (HP:0009046)1.48120113
166Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.47660470
167Round face (HP:0000311)1.47261304
168Obsessive-compulsive behavior (HP:0000722)1.46142661
169Lower limb muscle weakness (HP:0007340)1.45713776
170Bell-shaped thorax (HP:0001591)1.45587899
171Aneurysm (HP:0002617)1.45537875
172Joint laxity (HP:0001388)1.45072732
173Thyroid carcinoma (HP:0002890)1.44799794
174Broad long bones (HP:0005622)1.43009794
175Aortic regurgitation (HP:0001659)1.43006461
176Cerebral inclusion bodies (HP:0100314)1.42825591
177Abnormality of the lower motor neuron (HP:0002366)1.41634650
178Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.39634106
179Genu recurvatum (HP:0002816)1.38972894
180Osteoarthritis (HP:0002758)1.38891958
181Megalencephaly (HP:0001355)1.38829347
182Cystic hygroma (HP:0000476)1.38258074
183Transitional cell carcinoma of the bladder (HP:0006740)1.37598982

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK8.10190359
2MKNK24.91817068
3CLK14.85706895
4TLK13.34805506
5MKNK12.66309123
6TNIK2.46378988
7NTRK12.33302100
8PDGFRA2.04557146
9CDK122.01375683
10BRD41.99216656
11CAMK1D1.98071839
12MAP2K71.96060358
13RIPK11.95255959
14SRPK11.89981433
15NTRK31.87346098
16PRPF4B1.85964292
17AKT31.70181387
18PHKG21.67429432
19PHKG11.67429432
20FES1.67218152
21MAP3K91.67137438
22DMPK1.63172823
23TRIB31.59303595
24INSRR1.54137776
25MUSK1.51931652
26PKN21.49084348
27STK38L1.48804625
28SGK31.41180312
29NEK91.37245723
30MARK11.35508454
31FER1.34539253
32TYRO31.33649319
33PRKD31.29511781
34KSR11.27244813
35PDGFRB1.25147063
36MAPK131.20263913
37UHMK11.19335031
38EPHA41.16172921
39MET1.15095144
40MAP3K11.14970809
41CSNK1G11.13288801
42PNCK1.08711198
43PKN11.07592325
44MAP3K41.05502408
45RET1.04513001
46PAK31.03972179
47DYRK1A1.03022516
48PINK11.00980223
49MTOR1.00914331
50CDK190.99929509
51IRAK20.98935413
52YES10.97658621
53PTK20.97386432
54EPHA30.97278359
55EIF2AK20.93724769
56PAK20.92866431
57MAP3K60.92684336
58CSNK1A1L0.91870394
59TTN0.91529325
60NLK0.90588668
61DDR20.89938389
62ICK0.88185563
63EEF2K0.87010577
64PRKD20.84819147
65KSR20.82629050
66BMPR1B0.81729137
67MAP3K70.81570817
68CAMKK10.81544538
69PIK3CA0.80311147
70WNK10.80026131
71STK160.75960261
72FGR0.74854546
73CAMK2B0.74623057
74STK240.72259754
75NEK60.71780713
76IRAK10.71258910
77STK110.71167374
78ROCK20.70884599
79STK30.70245169
80OBSCN0.69249792
81CAMK2A0.68177536
82FGFR30.67599949
83STK380.66856067
84NTRK20.66496311
85BCR0.65673877
86MAP2K40.65647020
87STK390.65175593
88PRKCH0.64940790
89CDC42BPA0.64608855
90SGK20.64511057
91OXSR10.63985700
92CSNK1G30.62644695
93MAP2K10.62289473
94PLK20.61437699
95GRK70.61319268
96NUAK10.61101712
97CSNK1G20.59022226
98RPS6KB10.57835728
99CDK50.56810902
100RPS6KA20.56349906
101CDK30.56264535
102MYLK0.55759141
103MOS0.55579890
104CAMK1G0.55442818
105CAMK40.55213147
106EPHB20.55119416
107BLK0.54771310
108SIK10.54528615
109FRK0.54237022
110PRKCE0.53733285
111SGK4940.53380546
112SGK2230.53380546
113BMPR20.51348361
114MAPK100.51040316
115PRKD10.50693217
116ERBB20.49616334
117SIK20.49517289
118PRKAA10.47430401
119MINK10.47293602
120DYRK20.47188976
121ERBB30.47159429
122LATS20.46912834
123PRKCZ0.46556292
124PRKG10.45760539
125IRAK30.45732175
126FGFR10.44776160
127RPS6KA30.44648400
128CAMK10.44293751
129PIK3CG0.42823567
130GRK50.40985894
131CSNK1D0.40970379
132MAP3K120.40394529
133PAK10.39831747
134HIPK20.39300746
135SGK10.37906645
136ADRBK10.36136401
137ADRBK20.34495147
138NME20.34476660
139CSNK1E0.33937156
140NME10.32812083
141LATS10.32620488
142IRAK40.32595394
143MARK20.31942559
144PRKCG0.31577484
145ERBB40.31491629
146DAPK20.31255678
147PAK60.31085149
148WNK30.30979303
149CAMK2D0.30162181
150RIPK40.29317477
151PRKAA20.28721612
152FGFR20.28286920
153GRK10.27912899
154TAOK30.27416523
155PRKACA0.26210320
156ROCK10.24852215

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.23349430
2Phototransduction_Homo sapiens_hsa047442.73837115
3Long-term depression_Homo sapiens_hsa047302.24580882
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.05704591
5Morphine addiction_Homo sapiens_hsa050322.05596001
6Axon guidance_Homo sapiens_hsa043602.03129076
7Glutamatergic synapse_Homo sapiens_hsa047242.01548663
8Taste transduction_Homo sapiens_hsa047421.94328733
9Serotonergic synapse_Homo sapiens_hsa047261.93413579
10Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.92878561
11Adherens junction_Homo sapiens_hsa045201.73656129
12Wnt signaling pathway_Homo sapiens_hsa043101.72248876
13GABAergic synapse_Homo sapiens_hsa047271.69511496
14Melanogenesis_Homo sapiens_hsa049161.67613294
15Circadian entrainment_Homo sapiens_hsa047131.66793995
16Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.61745749
17Fanconi anemia pathway_Homo sapiens_hsa034601.60872040
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.53414173
19Long-term potentiation_Homo sapiens_hsa047201.51908959
20Amphetamine addiction_Homo sapiens_hsa050311.51420886
21Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.51032967
22Basal cell carcinoma_Homo sapiens_hsa052171.50333607
23Ether lipid metabolism_Homo sapiens_hsa005651.47208637
24Dopaminergic synapse_Homo sapiens_hsa047281.45863402
25GnRH signaling pathway_Homo sapiens_hsa049121.44351014
26Thyroid hormone signaling pathway_Homo sapiens_hsa049191.42795729
27Salivary secretion_Homo sapiens_hsa049701.40488623
28Calcium signaling pathway_Homo sapiens_hsa040201.38075944
29Cholinergic synapse_Homo sapiens_hsa047251.36389325
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.36037447
31Sphingolipid metabolism_Homo sapiens_hsa006001.33376623
32Insulin secretion_Homo sapiens_hsa049111.30724676
33Olfactory transduction_Homo sapiens_hsa047401.25398770
34Renin secretion_Homo sapiens_hsa049241.20616985
35Cocaine addiction_Homo sapiens_hsa050301.19938387
36mTOR signaling pathway_Homo sapiens_hsa041501.14062617
37Gap junction_Homo sapiens_hsa045401.11096576
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.08360924
39Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.08270028
40Hedgehog signaling pathway_Homo sapiens_hsa043401.08220641
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.08185025
42ErbB signaling pathway_Homo sapiens_hsa040121.06772650
43AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.05675022
44Colorectal cancer_Homo sapiens_hsa052101.04088130
45Oxytocin signaling pathway_Homo sapiens_hsa049211.04022827
46Notch signaling pathway_Homo sapiens_hsa043301.02621582
47Proteoglycans in cancer_Homo sapiens_hsa052051.01956324
48Melanoma_Homo sapiens_hsa052181.01792475
49Longevity regulating pathway - mammal_Homo sapiens_hsa042111.01539927
50Prostate cancer_Homo sapiens_hsa052151.00471666
51Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99992279
52cAMP signaling pathway_Homo sapiens_hsa040240.99739418
53Synaptic vesicle cycle_Homo sapiens_hsa047210.99307020
54Neurotrophin signaling pathway_Homo sapiens_hsa047220.99111090
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.98668167
56Lysine degradation_Homo sapiens_hsa003100.97670511
57Thyroid hormone synthesis_Homo sapiens_hsa049180.96209472
58Circadian rhythm_Homo sapiens_hsa047100.95244841
59Dorso-ventral axis formation_Homo sapiens_hsa043200.94976876
60Ras signaling pathway_Homo sapiens_hsa040140.94565653
61Vascular smooth muscle contraction_Homo sapiens_hsa042700.94307825
62Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.93431603
63AMPK signaling pathway_Homo sapiens_hsa041520.90510713
64MAPK signaling pathway_Homo sapiens_hsa040100.89066377
65Chronic myeloid leukemia_Homo sapiens_hsa052200.88811303
66Amoebiasis_Homo sapiens_hsa051460.88067482
67Insulin signaling pathway_Homo sapiens_hsa049100.86950600
68Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86828953
69VEGF signaling pathway_Homo sapiens_hsa043700.86391584
70Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.86180989
71Non-small cell lung cancer_Homo sapiens_hsa052230.85927466
72Maturity onset diabetes of the young_Homo sapiens_hsa049500.85632526
73Protein digestion and absorption_Homo sapiens_hsa049740.84246492
74Prolactin signaling pathway_Homo sapiens_hsa049170.83168499
75Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82653754
76Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82250096
77Platelet activation_Homo sapiens_hsa046110.81908860
78Protein export_Homo sapiens_hsa030600.80228543
79MicroRNAs in cancer_Homo sapiens_hsa052060.79288433
80Ovarian steroidogenesis_Homo sapiens_hsa049130.79039762
81Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78537343
82Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.78254922
83Choline metabolism in cancer_Homo sapiens_hsa052310.77965233
84Gastric acid secretion_Homo sapiens_hsa049710.77779614
85Pancreatic cancer_Homo sapiens_hsa052120.77617264
86Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.76941658
87Small cell lung cancer_Homo sapiens_hsa052220.75347807
88Phosphatidylinositol signaling system_Homo sapiens_hsa040700.72616599
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.71795211
90Alcoholism_Homo sapiens_hsa050340.71020485
91Fatty acid biosynthesis_Homo sapiens_hsa000610.65792320
92Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.65263609
93Hippo signaling pathway_Homo sapiens_hsa043900.65049124
94Phospholipase D signaling pathway_Homo sapiens_hsa040720.64563768
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64445129
96Arachidonic acid metabolism_Homo sapiens_hsa005900.62490784
97Glioma_Homo sapiens_hsa052140.61669438
98Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61396075
99Dilated cardiomyopathy_Homo sapiens_hsa054140.60079013
100Renal cell carcinoma_Homo sapiens_hsa052110.59848176
101Transcriptional misregulation in cancer_Homo sapiens_hsa052020.59404314
102Homologous recombination_Homo sapiens_hsa034400.58732197
103Rap1 signaling pathway_Homo sapiens_hsa040150.57195728
104Cardiac muscle contraction_Homo sapiens_hsa042600.56805914
105ECM-receptor interaction_Homo sapiens_hsa045120.55494663
106Estrogen signaling pathway_Homo sapiens_hsa049150.55133820
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.54507784
108Tight junction_Homo sapiens_hsa045300.54476369
109Thyroid cancer_Homo sapiens_hsa052160.53090971
110Pathways in cancer_Homo sapiens_hsa052000.52973599
111Type II diabetes mellitus_Homo sapiens_hsa049300.52340317
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51904205
113Autoimmune thyroid disease_Homo sapiens_hsa053200.48886565
114Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47290910
115Pancreatic secretion_Homo sapiens_hsa049720.46848393
116Endometrial cancer_Homo sapiens_hsa052130.46420957
117Glucagon signaling pathway_Homo sapiens_hsa049220.46306610
118Focal adhesion_Homo sapiens_hsa045100.44975694
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43703637
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.43178802
121Collecting duct acid secretion_Homo sapiens_hsa049660.41166391
122Ribosome_Homo sapiens_hsa030100.40656047
123Inositol phosphate metabolism_Homo sapiens_hsa005620.39357794
124TGF-beta signaling pathway_Homo sapiens_hsa043500.39141922
125Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36238246
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.35653426
127FoxO signaling pathway_Homo sapiens_hsa040680.35453062

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