RABGAP1L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)4.34905541
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.18367957
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.89238534
4negative regulation of cell killing (GO:0031342)3.89238534
5presynaptic membrane assembly (GO:0097105)3.86426141
6activated T cell proliferation (GO:0050798)3.80650614
7neutrophil activation involved in immune response (GO:0002283)3.76598802
8positive regulation of granulocyte differentiation (GO:0030854)3.68981123
9ionotropic glutamate receptor signaling pathway (GO:0035235)3.65910394
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.59522835
11regulation of short-term neuronal synaptic plasticity (GO:0048172)3.58673170
12NIK/NF-kappaB signaling (GO:0038061)3.56989787
13vocalization behavior (GO:0071625)3.55728853
14neuron cell-cell adhesion (GO:0007158)3.55150471
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.47917849
16regulation of glutamate receptor signaling pathway (GO:1900449)3.44464025
17exploration behavior (GO:0035640)3.42515867
18phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.39067569
19regulation of synaptic vesicle exocytosis (GO:2000300)3.33222280
20regulation of gamma-delta T cell differentiation (GO:0045586)3.33021788
21regulation of gamma-delta T cell activation (GO:0046643)3.31439540
22regulation of MHC class II biosynthetic process (GO:0045346)3.31298908
23presynaptic membrane organization (GO:0097090)3.25900383
24microglial cell activation (GO:0001774)3.23402317
25negative T cell selection (GO:0043383)3.22917120
26synaptic vesicle exocytosis (GO:0016079)3.21141950
27protein localization to synapse (GO:0035418)3.20072003
28glutamate receptor signaling pathway (GO:0007215)3.20062685
29antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.19019780
30protein neddylation (GO:0045116)3.18414686
31synaptic vesicle maturation (GO:0016188)3.18012585
32glutamate secretion (GO:0014047)3.17290100
33negative thymic T cell selection (GO:0045060)3.16650167
34thrombin receptor signaling pathway (GO:0070493)3.14192142
35dendritic spine morphogenesis (GO:0060997)3.09989036
36cellular response to interleukin-15 (GO:0071350)3.09762355
37protein K11-linked deubiquitination (GO:0035871)3.04867891
38synaptic transmission, glutamatergic (GO:0035249)2.99187252
39neutrophil activation (GO:0042119)2.99023868
40positive regulation of alpha-beta T cell proliferation (GO:0046641)2.98902603
41negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.98328766
42negative regulation of translation, ncRNA-mediated (GO:0040033)2.98328766
43regulation of translation, ncRNA-mediated (GO:0045974)2.98328766
44cellular response to ethanol (GO:0071361)2.98255749
45regulation of alpha-beta T cell proliferation (GO:0046640)2.97368367
46regulation of synaptic vesicle transport (GO:1902803)2.97101400
47regulation of excitatory postsynaptic membrane potential (GO:0060079)2.96211429
48regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.93734053
49regulation of regulatory T cell differentiation (GO:0045589)2.93155816
50cilium or flagellum-dependent cell motility (GO:0001539)2.93094013
51hepatocyte apoptotic process (GO:0097284)2.91354634
52negative regulation of B cell proliferation (GO:0030889)2.89977645
53regulation of long-term neuronal synaptic plasticity (GO:0048169)2.89770298
54establishment of protein localization to Golgi (GO:0072600)2.88803238
55purinergic nucleotide receptor signaling pathway (GO:0035590)2.88294856
56response to interleukin-15 (GO:0070672)2.88068639
57positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.87709074
58regulation of platelet aggregation (GO:0090330)2.87413980
59positive regulation of cAMP-mediated signaling (GO:0043950)2.85649805
60membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.85156369
61regulation of memory T cell differentiation (GO:0043380)2.85008814
62regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.84212031
63neuron-neuron synaptic transmission (GO:0007270)2.83954002
64negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.83829936
65positive regulation of gamma-delta T cell activation (GO:0046645)2.83405187
66positive regulation of membrane potential (GO:0045838)2.82975184
67regulation of ARF protein signal transduction (GO:0032012)2.82462601
68T cell migration (GO:0072678)2.80593504
69regulation of vesicle fusion (GO:0031338)2.79888264
70positive regulation of mast cell activation (GO:0033005)2.79876422
71neurotransmitter-gated ion channel clustering (GO:0072578)2.77923142
72regulation of postsynaptic membrane potential (GO:0060078)2.77652828
73cerebellar Purkinje cell differentiation (GO:0021702)2.76354702
74long-term memory (GO:0007616)2.75907666
75CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.74350422
76T-helper cell differentiation (GO:0042093)2.74350422
77negative regulation of T cell mediated immunity (GO:0002710)2.73962841
78monoubiquitinated protein deubiquitination (GO:0035520)2.73586357
79gamma-aminobutyric acid signaling pathway (GO:0007214)2.73382766
80postsynaptic membrane organization (GO:0001941)2.72952644
81negative regulation of synaptic transmission, GABAergic (GO:0032229)2.70079955
82G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.69931102
83neuronal action potential propagation (GO:0019227)2.69849434
84negative regulation of lymphocyte mediated immunity (GO:0002707)2.68791652
85negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.67649039
86negative regulation of T-helper cell differentiation (GO:0045623)2.67649039
87negative regulation of neurotransmitter transport (GO:0051589)2.65976166
88positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.64714779
89nerve growth factor signaling pathway (GO:0038180)2.64119876
90negative regulation of adaptive immune response (GO:0002820)2.63856553
91regulation of protein glycosylation (GO:0060049)2.63518603
92antigen processing and presentation of endogenous antigen (GO:0019883)2.62657481
93negative regulation of protein oligomerization (GO:0032460)2.62498896
94inositol phosphate dephosphorylation (GO:0046855)2.61928487
95phosphorylated carbohydrate dephosphorylation (GO:0046838)2.61928487
96transmission of nerve impulse (GO:0019226)2.61260595
97activation of protein kinase A activity (GO:0034199)2.61006742
98histone mRNA catabolic process (GO:0071044)2.60473677
99cellular potassium ion homeostasis (GO:0030007)2.59115221
100long-term synaptic potentiation (GO:0060291)2.59108567
101dendritic cell migration (GO:0036336)2.59054037
102positive T cell selection (GO:0043368)2.58885279
103synaptic vesicle docking involved in exocytosis (GO:0016081)2.58865522
104regulation of neuronal synaptic plasticity (GO:0048168)2.58562674
105dopamine transport (GO:0015872)2.58035931
106T cell selection (GO:0045058)2.57135371
107neural tube formation (GO:0001841)2.56609927
108glycosphingolipid biosynthetic process (GO:0006688)2.55443656
109negative regulation of heart rate (GO:0010459)2.54000217
110dendritic cell chemotaxis (GO:0002407)2.53559062
111interkinetic nuclear migration (GO:0022027)2.53479905
112antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.53429409
113antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.53429409
114regulation of platelet activation (GO:0010543)2.53229007
115negative regulation of dendrite morphogenesis (GO:0050774)2.53119458
116positive regulation of synaptic transmission, GABAergic (GO:0032230)2.53070277
117interferon-gamma production (GO:0032609)2.52939952
118inositol phosphate catabolic process (GO:0071545)2.52706840
119B cell receptor signaling pathway (GO:0050853)2.52561153
120T cell proliferation (GO:0042098)2.52404262
121neurotransmitter secretion (GO:0007269)2.51496385
122regulation of dendritic spine morphogenesis (GO:0061001)2.50990714
123negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.50507499
124epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.49206620
125Golgi to endosome transport (GO:0006895)2.47273782
126detection of calcium ion (GO:0005513)2.46147320
127regulation of voltage-gated calcium channel activity (GO:1901385)2.45892847
128membrane depolarization (GO:0051899)2.45807836
129protein targeting to Golgi (GO:0000042)2.45459585
130granulocyte activation (GO:0036230)2.45404609
131regulation of synapse structural plasticity (GO:0051823)2.44185759
132CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.43264440
133regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.42584704
134gamma-aminobutyric acid transport (GO:0015812)2.42034436
135regulation of inositol phosphate biosynthetic process (GO:0010919)2.41575519
136mast cell degranulation (GO:0043303)2.41162742
137mast cell activation involved in immune response (GO:0002279)2.41162742
138positive regulation of B cell differentiation (GO:0045579)2.41098084
139positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.40246537
140dendrite morphogenesis (GO:0048813)2.39771055
141myeloid cell activation involved in immune response (GO:0002275)2.39229414
142protein K48-linked deubiquitination (GO:0071108)2.38429831
143regulation of B cell receptor signaling pathway (GO:0050855)2.37910131
144regulation of synaptic transmission, glutamatergic (GO:0051966)2.37621086
145cellular extravasation (GO:0045123)2.37489402
146regulation of dendritic spine development (GO:0060998)2.37217022
147positive regulation of neurotransmitter secretion (GO:0001956)2.37175822
148retrograde transport, vesicle recycling within Golgi (GO:0000301)2.36003496
149regulation of B cell differentiation (GO:0045577)2.35764001
150antigen receptor-mediated signaling pathway (GO:0050851)2.35720673
151layer formation in cerebral cortex (GO:0021819)2.35604251
152synapse assembly (GO:0007416)2.35520018
153negative regulation of B cell activation (GO:0050869)2.35275871
154mast cell activation (GO:0045576)2.35257252
155phosphatidylinositol dephosphorylation (GO:0046856)2.35157522
156histone H3-K4 trimethylation (GO:0080182)2.34967343
157positive regulation of natural killer cell differentiation (GO:0032825)2.34893293
158positive regulation of developmental pigmentation (GO:0048087)2.34880677
159regulation of synaptic plasticity (GO:0048167)2.34249309
160neuron recognition (GO:0008038)2.33672213
161antigen processing and presentation via MHC class Ib (GO:0002475)2.33350128
162leukocyte migration involved in inflammatory response (GO:0002523)2.33027579
163positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.32800831
164regulation of cell communication by electrical coupling (GO:0010649)2.32659010
165regulation of mast cell activation (GO:0033003)2.32165506
166membrane assembly (GO:0071709)2.31871095
167central nervous system projection neuron axonogenesis (GO:0021952)2.31400378
168regulation of neurotransmitter secretion (GO:0046928)2.31133276
169alpha-beta T cell differentiation involved in immune response (GO:0002293)2.30591637
170alpha-beta T cell activation involved in immune response (GO:0002287)2.30591637
171T cell differentiation involved in immune response (GO:0002292)2.30591637
172termination of G-protein coupled receptor signaling pathway (GO:0038032)2.29885055
173B cell mediated immunity (GO:0019724)2.28431699
174leukocyte degranulation (GO:0043299)2.27685148
175regulation of pigment cell differentiation (GO:0050932)2.26327388
176protein prenylation (GO:0018342)2.25700827
177prenylation (GO:0097354)2.25700827
178regulation of establishment of cell polarity (GO:2000114)2.25519385
179negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.24060347
180tolerance induction (GO:0002507)2.23568774
181negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.22925374
182B cell proliferation (GO:0042100)2.22863539
183negative regulation of B cell mediated immunity (GO:0002713)2.22114841

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.09949246
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.40289596
3GBX2_23144817_ChIP-Seq_PC3_Human3.20072325
4SMAD_19615063_ChIP-ChIP_OVARY_Human2.53357600
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.53318807
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.16452875
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.14635547
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.14538677
9TAF15_26573619_Chip-Seq_HEK293_Human2.11750946
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.06265479
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.02767625
12DROSHA_22980978_ChIP-Seq_HELA_Human1.98823911
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.97086067
14VDR_22108803_ChIP-Seq_LS180_Human1.92662070
15VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.89784681
16AR_21572438_ChIP-Seq_LNCaP_Human1.86640609
17SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.85228239
18ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84751307
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.84259587
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.76386268
21RUNX_20019798_ChIP-Seq_JUKART_Human1.76060546
22MTF2_20144788_ChIP-Seq_MESCs_Mouse1.71951646
23SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.69638238
24* SMAD4_21799915_ChIP-Seq_A2780_Human1.67401772
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.66556103
26* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65881494
27PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.64697330
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.64475015
29GATA1_22025678_ChIP-Seq_K562_Human1.63268917
30EZH2_18974828_ChIP-Seq_MESCs_Mouse1.60887207
31RNF2_18974828_ChIP-Seq_MESCs_Mouse1.60887207
32EWS_26573619_Chip-Seq_HEK293_Human1.59343428
33P300_19829295_ChIP-Seq_ESCs_Human1.58935255
34REST_21632747_ChIP-Seq_MESCs_Mouse1.58070932
35TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57433039
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.54067961
37IGF1R_20145208_ChIP-Seq_DFB_Human1.53360669
38JARID2_20075857_ChIP-Seq_MESCs_Mouse1.52435715
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.51428440
40SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.50945393
41LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.49946034
42* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.48704645
43RNF2_27304074_Chip-Seq_ESCs_Mouse1.46272108
44SUZ12_27294783_Chip-Seq_ESCs_Mouse1.43946071
45IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.43122510
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.42629171
47* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.42433472
48IKZF1_21737484_ChIP-ChIP_HCT116_Human1.41730988
49AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.41569364
50UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.41418675
51BCAT_22108803_ChIP-Seq_LS180_Human1.39737066
52IRF8_27001747_Chip-Seq_BMDM_Mouse1.38035901
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.37587593
54SALL1_21062744_ChIP-ChIP_HESCs_Human1.36619229
55EZH2_27304074_Chip-Seq_ESCs_Mouse1.36386450
56MYB_26560356_Chip-Seq_TH2_Human1.36377601
57EZH2_27294783_Chip-Seq_ESCs_Mouse1.36377284
58Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.36230598
59PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.35985206
60CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33028430
61CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32974380
62GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32558531
63RARB_27405468_Chip-Seq_BRAIN_Mouse1.31790822
64EED_16625203_ChIP-ChIP_MESCs_Mouse1.31597987
65PCGF2_27294783_Chip-Seq_ESCs_Mouse1.31458245
66* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.31394403
67* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29799293
68* NANOG_18555785_Chip-Seq_ESCs_Mouse1.29206121
69* IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.28685540
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.28222658
71* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27904728
72ZNF217_24962896_ChIP-Seq_MCF-7_Human1.27356087
73* CRX_20693478_ChIP-Seq_RETINA_Mouse1.26682833
74FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.25775876
75STAT3_23295773_ChIP-Seq_U87_Human1.25381878
76* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.24848729
77* AR_25329375_ChIP-Seq_VCAP_Human1.24678081
78* ARNT_22903824_ChIP-Seq_MCF-7_Human1.23720274
79TCF4_23295773_ChIP-Seq_U87_Human1.22351893
80AHR_22903824_ChIP-Seq_MCF-7_Human1.22195801
81GATA3_26560356_Chip-Seq_TH2_Human1.21613763
82PIAS1_25552417_ChIP-Seq_VCAP_Human1.21496851
83GATA3_27048872_Chip-Seq_THYMUS_Human1.19096357
84FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.18829898
85SMAD3_21741376_ChIP-Seq_EPCs_Human1.18714948
86FLI1_21867929_ChIP-Seq_TH2_Mouse1.17269161
87PRDM14_20953172_ChIP-Seq_ESCs_Human1.17102775
88* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.16604991
89* SOX2_21211035_ChIP-Seq_LN229_Gbm1.15843502
90* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15165172
91* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14768522
92IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.14682658
93CBP_20019798_ChIP-Seq_JUKART_Human1.14682658
94* E2F1_18555785_Chip-Seq_ESCs_Mouse1.14638570
95ZNF274_21170338_ChIP-Seq_K562_Hela1.14034526
96CDX2_22108803_ChIP-Seq_LS180_Human1.13861830
97* P53_22387025_ChIP-Seq_ESCs_Mouse1.13785945
98SALL4_22934838_ChIP-ChIP_CD34+_Human1.13621657
99IRF1_19129219_ChIP-ChIP_H3396_Human1.13458525
100* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12646365
101* CMYC_18555785_Chip-Seq_ESCs_Mouse1.12535775
102* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.12478576
103* STAT3_18555785_Chip-Seq_ESCs_Mouse1.11823332
104SMRT_27268052_Chip-Seq_Bcells_Human1.10975234
105* ER_23166858_ChIP-Seq_MCF-7_Human1.09078350
106* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.08809274
107POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08025776
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08025776
109* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07522202
110* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.07133628
111TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06698491
112TCF4_22108803_ChIP-Seq_LS180_Human1.06031724
113NANOG_19829295_ChIP-Seq_ESCs_Human1.05423594
114SOX2_19829295_ChIP-Seq_ESCs_Human1.05423594
115TP53_18474530_ChIP-ChIP_U2OS_Human1.04422446
116* OCT4_18555785_Chip-Seq_ESCs_Mouse1.04354554
117* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.04229944
118* EZH2_27294783_Chip-Seq_NPCs_Mouse1.03690659
119* REST_18959480_ChIP-ChIP_MESCs_Mouse1.02676653
120VDR_24787735_ChIP-Seq_THP-1_Human1.01978260
121* NFE2_27457419_Chip-Seq_LIVER_Mouse1.00936516
122KDM2B_26808549_Chip-Seq_REH_Human0.99372067
123* SOX2_18555785_Chip-Seq_ESCs_Mouse0.99222433
124FUS_26573619_Chip-Seq_HEK293_Human0.99022338
125SCL_19346495_ChIP-Seq_HPC-7_Human0.98733850
126MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.98697732
127PCGF2_27294783_Chip-Seq_NPCs_Mouse0.97704024
128* NMYC_18555785_Chip-Seq_ESCs_Mouse0.97148908
129P53_22127205_ChIP-Seq_FIBROBLAST_Human0.96967469
130RUNX2_22187159_ChIP-Seq_PCA_Human0.96772961
131* P300_18555785_Chip-Seq_ESCs_Mouse0.96341590
132RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.95802673
133MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95743682
134* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95419067

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.94387022
2MP0005464_abnormal_platelet_physiology3.75568614
3MP0003880_abnormal_central_pattern3.74629505
4MP0008877_abnormal_DNA_methylation3.10737004
5MP0003635_abnormal_synaptic_transmissio2.97785330
6MP0008057_abnormal_DNA_replication2.96132647
7MP0003724_increased_susceptibility_to2.79983667
8MP0009745_abnormal_behavioral_response2.68036112
9MP0004270_analgesia2.48767748
10MP0001968_abnormal_touch/_nociception2.45653311
11MP0004510_myositis2.43215005
12MP0000569_abnormal_digit_pigmentation2.41785475
13MP0002166_altered_tumor_susceptibility2.34265021
14MP0002063_abnormal_learning/memory/cond2.32982269
15MP0002064_seizures2.20232944
16MP0002138_abnormal_hepatobiliary_system2.16546668
17MP0002009_preneoplasia2.15561320
18MP0002735_abnormal_chemical_nociception2.12634987
19MP0001984_abnormal_olfaction2.11547809
20MP0001835_abnormal_antigen_presentation2.09784058
21MP0009046_muscle_twitch2.09474554
22MP0002736_abnormal_nociception_after2.02981823
23MP0001486_abnormal_startle_reflex2.00898473
24MP0005423_abnormal_somatic_nervous1.98731470
25MP0005671_abnormal_response_to1.97651892
26MP0002272_abnormal_nervous_system1.97201612
27MP0002572_abnormal_emotion/affect_behav1.96986473
28MP0001790_abnormal_immune_system1.96099965
29MP0005387_immune_system_phenotype1.96099965
30MP0002006_tumorigenesis1.84900611
31MP0001501_abnormal_sleep_pattern1.83902138
32MP0003787_abnormal_imprinting1.79544287
33MP0000685_abnormal_immune_system1.77925014
34MP0001348_abnormal_lacrimal_gland1.75234811
35MP0003763_abnormal_thymus_physiology1.74276310
36MP0008004_abnormal_stomach_pH1.72572454
37MP0000465_gastrointestinal_hemorrhage1.67317540
38MP0002734_abnormal_mechanical_nocicepti1.67250275
39MP0001800_abnormal_humoral_immune1.62991685
40MP0008569_lethality_at_weaning1.61843356
41MP0003879_abnormal_hair_cell1.61255171
42MP0003656_abnormal_erythrocyte_physiolo1.60431792
43MP0005409_darkened_coat_color1.58881629
44MP0003303_peritoneal_inflammation1.58876706
45MP0005310_abnormal_salivary_gland1.57448721
46MP0005174_abnormal_tail_pigmentation1.54729480
47MP0005075_abnormal_melanosome_morpholog1.51625875
48MP0003195_calcinosis1.49023674
49MP0002067_abnormal_sensory_capabilities1.47806972
50MP0001188_hyperpigmentation1.44242865
51MP0002254_reproductive_system_inflammat1.41788479
52MP0001440_abnormal_grooming_behavior1.40077020
53MP0005645_abnormal_hypothalamus_physiol1.39621194
54MP0009780_abnormal_chondrocyte_physiolo1.37626750
55MP0000778_abnormal_nervous_system1.36781589
56MP0002723_abnormal_immune_serum1.36147452
57MP0005646_abnormal_pituitary_gland1.35398984
58MP0002420_abnormal_adaptive_immunity1.35076593
59MP0010155_abnormal_intestine_physiology1.34755743
60MP0001819_abnormal_immune_cell1.33568889
61MP0005000_abnormal_immune_tolerance1.32646695
62MP0002148_abnormal_hypersensitivity_rea1.29317018
63MP0004924_abnormal_behavior1.28661631
64MP0005386_behavior/neurological_phenoty1.28661631
65MP0002452_abnormal_antigen_presenting1.28118975
66MP0001970_abnormal_pain_threshold1.27918053
67MP0001873_stomach_inflammation1.24448654
68MP0002722_abnormal_immune_system1.23508300
69MP0010234_abnormal_vibrissa_follicle1.22747269
70MP0001986_abnormal_taste_sensitivity1.22262538
71MP0002184_abnormal_innervation1.20800017
72MP0002557_abnormal_social/conspecific_i1.20794361
73MP0004885_abnormal_endolymph1.19423649
74MP0001502_abnormal_circadian_rhythm1.18540700
75MP0002733_abnormal_thermal_nociception1.18508640
76MP0002398_abnormal_bone_marrow1.18434650
77MP0002876_abnormal_thyroid_physiology1.16979750
78MP0002163_abnormal_gland_morphology1.15822041
79MP0005167_abnormal_blood-brain_barrier1.15592238
80MP0003633_abnormal_nervous_system1.13771773
81MP0002822_catalepsy1.13746970
82MP0004811_abnormal_neuron_physiology1.12242857
83MP0005379_endocrine/exocrine_gland_phen1.11304712
84MP0000015_abnormal_ear_pigmentation1.10964059
85MP0000716_abnormal_immune_system1.10862666
86MP0004084_abnormal_cardiac_muscle1.10600093
87MP0009785_altered_susceptibility_to1.09829967
88MP0005084_abnormal_gallbladder_morpholo1.07212530
89MP0008872_abnormal_physiological_respon1.06914022
90MP0005083_abnormal_biliary_tract1.06240202
91MP0001845_abnormal_inflammatory_respons1.06094629
92MP0004484_altered_response_of1.05105537
93MP0002693_abnormal_pancreas_physiology1.04339973
94MP0004381_abnormal_hair_follicle1.03404482
95MP0000230_abnormal_systemic_arterial1.03086209
96MP0002396_abnormal_hematopoietic_system1.02229954
97MP0004147_increased_porphyrin_level1.02134233
98MP0002837_dystrophic_cardiac_calcinosis1.01622253
99MP0003183_abnormal_peptide_metabolism0.99827444
100MP0004043_abnormal_pH_regulation0.99217030
101MP0002405_respiratory_system_inflammati0.99035356
102MP0006276_abnormal_autonomic_nervous0.97686212
103MP0008961_abnormal_basal_metabolism0.97376734
104MP0003866_abnormal_defecation0.96696953
105MP0004215_abnormal_myocardial_fiber0.96062401
106MP0008874_decreased_physiological_sensi0.95292631
107MP0000920_abnormal_myelination0.93410562
108MP0005551_abnormal_eye_electrophysiolog0.91261090
109MP0005025_abnormal_response_to0.90626164
110MP0004130_abnormal_muscle_cell0.90390229
111MP0004742_abnormal_vestibular_system0.87515566
112MP0003045_fibrosis0.87197012
113MP0001905_abnormal_dopamine_level0.86836874
114MP0002066_abnormal_motor_capabilities/c0.85209423
115MP0000955_abnormal_spinal_cord0.84923649
116MP0002882_abnormal_neuron_morphology0.83826573
117MP0003631_nervous_system_phenotype0.83702714
118MP0000703_abnormal_thymus_morphology0.82861658
119MP0002102_abnormal_ear_morphology0.82467587
120MP0002419_abnormal_innate_immunity0.82397046
121MP0009764_decreased_sensitivity_to0.82028846
122MP0001963_abnormal_hearing_physiology0.81683832
123MP0005535_abnormal_body_temperature0.81308223
124MP0002095_abnormal_skin_pigmentation0.80193074
125MP0003172_abnormal_lysosome_physiology0.79475607
126MP0002277_abnormal_respiratory_mucosa0.78992272
127MP0004142_abnormal_muscle_tone0.78708553
128MP0000427_abnormal_hair_cycle0.78127705
129MP0001765_abnormal_ion_homeostasis0.77017717
130MP0002909_abnormal_adrenal_gland0.74789791
131MP0001851_eye_inflammation0.74639907
132MP0009763_increased_sensitivity_to0.72726404
133MP0002928_abnormal_bile_duct0.72168041
134MP0002429_abnormal_blood_cell0.71720098
135MP0000604_amyloidosis0.70823782
136MP0000689_abnormal_spleen_morphology0.70121350
137MP0004883_abnormal_blood_vessel0.69386300
138MP0006082_CNS_inflammation0.68970751
139MP0003121_genomic_imprinting0.67133003
140MP0010329_abnormal_lipoprotein_level0.66287296
141MP0001545_abnormal_hematopoietic_system0.65904563
142MP0005397_hematopoietic_system_phenotyp0.65904563

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.19037728
2Prolonged bleeding time (HP:0003010)5.00765398
3Febrile seizures (HP:0002373)4.33029073
4Focal seizures (HP:0007359)4.00617706
5Epileptic encephalopathy (HP:0200134)3.96192908
6Menorrhagia (HP:0000132)3.61827112
7Atonic seizures (HP:0010819)3.60939603
8Increased mean platelet volume (HP:0011877)3.57091753
9Agammaglobulinemia (HP:0004432)3.54755370
10Myokymia (HP:0002411)3.50994830
11Abnormal platelet volume (HP:0011876)3.45634450
12Epistaxis (HP:0000421)3.43314338
13Gingival bleeding (HP:0000225)3.42799977
14Visual hallucinations (HP:0002367)3.41083822
15Stomatitis (HP:0010280)3.40710388
16Hyperventilation (HP:0002883)3.34686322
17Petechiae (HP:0000967)3.28332339
18Chronic otitis media (HP:0000389)3.22511168
19Papilledema (HP:0001085)3.11213184
20Broad-based gait (HP:0002136)3.07831893
21Thyroiditis (HP:0100646)3.03785648
22Progressive cerebellar ataxia (HP:0002073)3.01321134
23Supranuclear gaze palsy (HP:0000605)2.98475676
24Absence seizures (HP:0002121)2.90123087
25Spontaneous hematomas (HP:0007420)2.84278441
26Recurrent viral infections (HP:0004429)2.83196472
27Gastrointestinal stroma tumor (HP:0100723)2.81681869
28Abnormal delayed hypersensitivity skin test (HP:0002963)2.79725511
29Gaze-evoked nystagmus (HP:0000640)2.77008311
30Chronic diarrhea (HP:0002028)2.76866528
31Abnormality of T cells (HP:0002843)2.72639920
32Progressive inability to walk (HP:0002505)2.70087754
33Recurrent bronchitis (HP:0002837)2.68469531
34Recurrent fungal infections (HP:0002841)2.64338994
35Poikilocytosis (HP:0004447)2.63790108
36IgA deficiency (HP:0002720)2.63216253
37Chronic sinusitis (HP:0011109)2.61534171
38Dialeptic seizures (HP:0011146)2.59702857
39Abnormality of the fingertips (HP:0001211)2.57516786
40Recurrent bacterial skin infections (HP:0005406)2.53639320
41Truncal ataxia (HP:0002078)2.52768665
42Drooling (HP:0002307)2.49977434
43Excessive salivation (HP:0003781)2.49977434
44Hyperlipoproteinemia (HP:0010980)2.49061921
45Abnormality of T cell number (HP:0011839)2.46648380
46Panhypogammaglobulinemia (HP:0003139)2.46169738
47Poor eye contact (HP:0000817)2.45815748
48Purpura (HP:0000979)2.40354381
49Generalized tonic-clonic seizures (HP:0002069)2.39246178
50B lymphocytopenia (HP:0010976)2.39113520
51Abnormality of B cell number (HP:0010975)2.39113520
52Encephalitis (HP:0002383)2.38243779
53Chronic mucocutaneous candidiasis (HP:0002728)2.37813717
54Recurrent cutaneous fungal infections (HP:0011370)2.37813717
55Scanning speech (HP:0002168)2.36329983
56Acanthocytosis (HP:0001927)2.35101147
57Urinary bladder sphincter dysfunction (HP:0002839)2.33023911
58Vasculitis (HP:0002633)2.32386176
59Generalized hypopigmentation of hair (HP:0011358)2.31483491
60Hypothermia (HP:0002045)2.31255805
61Protruding tongue (HP:0010808)2.30497341
62Diplopia (HP:0000651)2.29237806
63Abnormality of binocular vision (HP:0011514)2.29237806
64Bronchiectasis (HP:0002110)2.27544603
65T lymphocytopenia (HP:0005403)2.24993258
66Intention tremor (HP:0002080)2.24903661
67Optic neuritis (HP:0100653)2.24748544
68Retrobulbar optic neuritis (HP:0100654)2.24748544
69Abnormal hair whorl (HP:0010721)2.24263856
70Recurrent sinusitis (HP:0011108)2.23887252
71Action tremor (HP:0002345)2.23834071
72Meningitis (HP:0001287)2.21862813
73Dysmetria (HP:0001310)2.20067979
74Chronic hepatic failure (HP:0100626)2.19734747
75Macroorchidism (HP:0000053)2.18626587
76Fair hair (HP:0002286)2.15778871
77IgG deficiency (HP:0004315)2.14711327
78Dyschromatopsia (HP:0007641)2.13065471
79Autoimmune hemolytic anemia (HP:0001890)2.12240459
80Biliary tract neoplasm (HP:0100574)2.11756821
81Blue irides (HP:0000635)2.11540739
82Conjunctival telangiectasia (HP:0000524)2.11075059
83Abnormal social behavior (HP:0012433)2.10511070
84Impaired social interactions (HP:0000735)2.10511070
85Stomach cancer (HP:0012126)2.09742038
86Increased IgM level (HP:0003496)2.09489910
87IgM deficiency (HP:0002850)2.08444431
88Widely spaced teeth (HP:0000687)2.07970166
89Pancreatic cysts (HP:0001737)2.06391238
90Abnormality of salivation (HP:0100755)2.04526325
91Verrucae (HP:0200043)2.04496324
92Papilloma (HP:0012740)2.04496324
93Abnormality of eosinophils (HP:0001879)2.04253288
94Eczematoid dermatitis (HP:0000976)2.04022092
95Joint swelling (HP:0001386)2.03687257
96Inability to walk (HP:0002540)2.03659332
97Aqueductal stenosis (HP:0002410)2.02860909
98Abnormal respiratory epithelium morphology (HP:0012253)2.02733675
99Abnormal respiratory motile cilium morphology (HP:0005938)2.02733675
100Abnormality of the renal cortex (HP:0011035)2.02062259
101Recurrent abscess formation (HP:0002722)2.01500597
102Akinesia (HP:0002304)2.00798507
103Lymphopenia (HP:0001888)2.00506709
104Thyroid carcinoma (HP:0002890)1.99760288
105Impaired vibration sensation in the lower limbs (HP:0002166)1.99239615
106Abnormal ciliary motility (HP:0012262)1.99210661
107Eosinophilia (HP:0001880)1.98309011
108Arterial thrombosis (HP:0004420)1.97703683
109Leukocytosis (HP:0001974)1.97685489
110Genetic anticipation (HP:0003743)1.96858540
111Neoplasm of the tracheobronchial system (HP:0100552)1.94328425
112Absent speech (HP:0001344)1.94317424
113Inflammation of the large intestine (HP:0002037)1.93910897
114Impaired smooth pursuit (HP:0007772)1.93895962
115Bronchitis (HP:0012387)1.93347599
116Abnormality of cells of the lymphoid lineage (HP:0012140)1.92835624
117Postural instability (HP:0002172)1.92521949
118Abnormality of the vasculature of the conjunctiva (HP:0008054)1.92162199
119Urinary urgency (HP:0000012)1.91796243
120Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.91716260
121Stereotypic behavior (HP:0000733)1.90576669
122Spastic gait (HP:0002064)1.89664664
123Acute lymphatic leukemia (HP:0006721)1.88772682
124Hemiplegia (HP:0002301)1.88713949
125Hematochezia (HP:0002573)1.87182061
126Papillary thyroid carcinoma (HP:0002895)1.86014258
127Absent frontal sinuses (HP:0002688)1.85972499
128Recurrent skin infections (HP:0001581)1.85919188
129Abnormality of T cell physiology (HP:0011840)1.85743735
130Abnormality of the corticospinal tract (HP:0002492)1.84836290
131Neurofibrillary tangles (HP:0002185)1.83747266
132Anxiety (HP:0000739)1.82796835
133Hypoplasia of the thymus (HP:0000778)1.82738125
134Increased density of long bones (HP:0006392)1.82477930
135Myositis (HP:0100614)1.81667901
136Inappropriate behavior (HP:0000719)1.81385193
137Hypochromic microcytic anemia (HP:0004840)1.80861632
138Absent/shortened dynein arms (HP:0200106)1.80576307
139Dynein arm defect of respiratory motile cilia (HP:0012255)1.80576307
140Pulmonary infiltrates (HP:0002113)1.78492942
141Central scotoma (HP:0000603)1.78328773
142Decreased central vision (HP:0007663)1.78037920
143Neoplasm of the adrenal cortex (HP:0100641)1.78019718
144Colitis (HP:0002583)1.77644789
145Polyphagia (HP:0002591)1.77337104
146Abnormal platelet function (HP:0011869)1.77242602
147Impaired platelet aggregation (HP:0003540)1.77242602
148Abnormality of the prostate (HP:0008775)1.77236631
149Keratoconjunctivitis (HP:0001096)1.76942545
150Keratoconjunctivitis sicca (HP:0001097)1.76440254
151Abolished electroretinogram (ERG) (HP:0000550)1.75478423
152Clumsiness (HP:0002312)1.74697299
153Chest pain (HP:0100749)1.73111263
154Pancreatic fibrosis (HP:0100732)1.69952234
155Renal cortical cysts (HP:0000803)1.69936440
156Orchitis (HP:0100796)1.69269447

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK3.59379413
2MST43.36711027
3NTRK33.22324615
4MAP3K133.02151546
5ACVR1B2.75276938
6RIPK42.67723965
7FRK2.66892028
8MAP3K142.61531589
9MARK12.51908624
10CASK2.23657722
11NLK2.19550837
12MAP2K72.18894161
13EPHA42.16204159
14MAP3K122.10375469
15MAP3K41.92026952
16TXK1.83218106
17FGFR21.76753690
18MAP3K91.70896956
19BLK1.68795224
20FES1.67413184
21SIK21.50023337
22PIK3CG1.46536116
23FGFR31.45422856
24MAPK131.45207778
25BMPR1B1.44888424
26JAK11.38916270
27MAP4K11.37445831
28PTK2B1.37136429
29JAK31.35939088
30SYK1.34142263
31INSRR1.33443429
32MINK11.32796339
33KIT1.26102668
34BMPR21.25044090
35ADRBK21.23063724
36MAP3K71.21739663
37NTRK21.16759314
38FGR1.15770595
39PKN11.15514106
40PRKCQ1.13588918
41IKBKE1.13554086
42DAPK21.12054918
43WNK31.11060934
44GRK51.10994158
45PLK21.07974254
46CDK51.06836988
47TEC1.06515287
48ZAK1.05954549
49SGK21.04664506
50LYN1.04494276
51MAP3K21.03469140
52NUAK11.01285786
53STK31.00025246
54IRAK10.99158961
55PHKG20.97766695
56PHKG10.97766695
57STK110.97324522
58BCR0.96979195
59PRPF4B0.96690757
60MAP2K40.96060818
61DAPK10.95760096
62CSK0.92915616
63GRK60.91158798
64RET0.90867031
65TYK20.89647623
66TAOK30.89194308
67FER0.88789566
68MKNK20.87055674
69SIK30.85905001
70CDK190.85530899
71TRIM280.85449602
72SGK10.85225584
73STK40.84514938
74IRAK40.83018800
75IKBKB0.82171500
76SGK30.81412712
77MARK30.81038418
78GRK10.80732301
79PDK10.79229231
80BRSK20.78328553
81STK240.77274273
82AKT30.76858343
83PIM10.75149606
84WNK10.74562911
85DYRK1A0.74512433
86PAK60.74108222
87PRKCH0.73399834
88BMX0.73300447
89RAF10.72352741
90CSF1R0.71068671
91STK38L0.70908259
92CAMKK10.70147147
93CAMK10.69880118
94TNK20.69762030
95MARK20.69739690
96LCK0.69422975
97ITK0.68329365
98NTRK10.66498694
99ERBB20.66245492
100HCK0.64865516
101KSR20.63661334
102HIPK20.63366858
103OXSR10.63353201
104CAMKK20.63243343
105SGK4940.62654421
106SGK2230.62654421
107MYLK0.62530779
108FYN0.61411088
109PIK3CA0.61098180
110CSNK1G20.60792468
111PRKAA20.60697768
112CAMK2A0.60373315
113YES10.60320406
114CHUK0.59012736
115ZAP700.58678055
116NEK60.57895247
117PRKCE0.56188279
118MAPK120.54465468
119KSR10.54322889
120CSNK1A1L0.52488320
121MAP4K20.52401359
122ADRBK10.49560164
123STK390.49555561
124TBK10.49319782
125TRPM70.49041330
126PAK30.48888082
127PRKCZ0.48242932
128LMTK20.46062821
129EGFR0.44910183
130EPHA30.44635090
131BTK0.44261569
132CAMK2B0.43665611
133DMPK0.42960554
134PRKCG0.42953606
135BRD40.42623917
136CAMK1G0.42388758
137MATK0.42149704
138PDPK10.41853275
139JAK20.41551818
140UHMK10.41500106
141TAF10.38161543
142MAP3K50.35714422
143PLK30.35297418
144PRKCB0.34832586
145PRKG10.30653257
146TLK10.28797836

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.71911126
2Olfactory transduction_Homo sapiens_hsa047402.58882670
3Circadian entrainment_Homo sapiens_hsa047132.15284408
4Morphine addiction_Homo sapiens_hsa050322.12697937
5Glutamatergic synapse_Homo sapiens_hsa047242.08627819
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.06183045
7Long-term potentiation_Homo sapiens_hsa047202.06144799
8Asthma_Homo sapiens_hsa053101.86376403
9GABAergic synapse_Homo sapiens_hsa047271.75581935
10Salivary secretion_Homo sapiens_hsa049701.75400834
11Amphetamine addiction_Homo sapiens_hsa050311.74148700
12Primary immunodeficiency_Homo sapiens_hsa053401.71285855
13Renin secretion_Homo sapiens_hsa049241.63918134
14Cholinergic synapse_Homo sapiens_hsa047251.63238413
15B cell receptor signaling pathway_Homo sapiens_hsa046621.57126628
16Phosphatidylinositol signaling system_Homo sapiens_hsa040701.55027727
17Gastric acid secretion_Homo sapiens_hsa049711.53416083
18Taste transduction_Homo sapiens_hsa047421.50580892
19T cell receptor signaling pathway_Homo sapiens_hsa046601.47884634
20Linoleic acid metabolism_Homo sapiens_hsa005911.47649810
21Dopaminergic synapse_Homo sapiens_hsa047281.45922119
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.45731266
23Intestinal immune network for IgA production_Homo sapiens_hsa046721.43987351
24Synaptic vesicle cycle_Homo sapiens_hsa047211.41088627
25Insulin secretion_Homo sapiens_hsa049111.40968382
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.38953141
27Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.34042413
28Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.33981591
29Maturity onset diabetes of the young_Homo sapiens_hsa049501.33636371
30Oxytocin signaling pathway_Homo sapiens_hsa049211.32096271
31Calcium signaling pathway_Homo sapiens_hsa040201.28451676
32Staphylococcus aureus infection_Homo sapiens_hsa051501.27147478
33Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24667673
34Serotonergic synapse_Homo sapiens_hsa047261.23004626
35Nitrogen metabolism_Homo sapiens_hsa009101.21796176
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.21457020
37cAMP signaling pathway_Homo sapiens_hsa040241.20427318
38Chemokine signaling pathway_Homo sapiens_hsa040621.20361922
39Type II diabetes mellitus_Homo sapiens_hsa049301.19188691
40Long-term depression_Homo sapiens_hsa047301.17573462
41Systemic lupus erythematosus_Homo sapiens_hsa053221.15870635
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.14593113
43Allograft rejection_Homo sapiens_hsa053301.14338228
44NF-kappa B signaling pathway_Homo sapiens_hsa040641.13845293
45Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.13223313
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.13127440
47Dorso-ventral axis formation_Homo sapiens_hsa043201.10624197
48Ether lipid metabolism_Homo sapiens_hsa005651.08436295
49GnRH signaling pathway_Homo sapiens_hsa049121.08434587
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08125535
51Antigen processing and presentation_Homo sapiens_hsa046121.06738071
52ErbB signaling pathway_Homo sapiens_hsa040121.04582960
53Osteoclast differentiation_Homo sapiens_hsa043801.04256635
54cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00265722
55Arachidonic acid metabolism_Homo sapiens_hsa005900.99693061
56Cocaine addiction_Homo sapiens_hsa050300.99396746
57Autoimmune thyroid disease_Homo sapiens_hsa053200.98361280
58Glioma_Homo sapiens_hsa052140.97884858
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.97490654
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.93865423
61ABC transporters_Homo sapiens_hsa020100.92060126
62Inositol phosphate metabolism_Homo sapiens_hsa005620.91240273
63Type I diabetes mellitus_Homo sapiens_hsa049400.90303256
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.89930111
65Axon guidance_Homo sapiens_hsa043600.89271277
66Circadian rhythm_Homo sapiens_hsa047100.87872169
67Estrogen signaling pathway_Homo sapiens_hsa049150.86823737
68Measles_Homo sapiens_hsa051620.86701120
69Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.86694742
70Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.86419443
71MAPK signaling pathway_Homo sapiens_hsa040100.86117002
72Graft-versus-host disease_Homo sapiens_hsa053320.85913271
73Choline metabolism in cancer_Homo sapiens_hsa052310.85518036
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.84434917
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.82823421
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.82028793
77Platelet activation_Homo sapiens_hsa046110.81599777
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.81327487
79Non-small cell lung cancer_Homo sapiens_hsa052230.81262225
80Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81171483
81Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.81015622
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79950974
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.79310012
84TNF signaling pathway_Homo sapiens_hsa046680.79216520
85Alcoholism_Homo sapiens_hsa050340.78932615
86Non-homologous end-joining_Homo sapiens_hsa034500.77995154
87Viral myocarditis_Homo sapiens_hsa054160.77717513
88Regulation of autophagy_Homo sapiens_hsa041400.77706529
89African trypanosomiasis_Homo sapiens_hsa051430.77097119
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.76894515
91Hematopoietic cell lineage_Homo sapiens_hsa046400.76799066
92Prolactin signaling pathway_Homo sapiens_hsa049170.76278358
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75521630
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74800031
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73372489
96Herpes simplex infection_Homo sapiens_hsa051680.71392956
97Toxoplasmosis_Homo sapiens_hsa051450.70052411
98Jak-STAT signaling pathway_Homo sapiens_hsa046300.70050795
99Endometrial cancer_Homo sapiens_hsa052130.69742102
100Ras signaling pathway_Homo sapiens_hsa040140.69326976
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69275542
102Gap junction_Homo sapiens_hsa045400.68886632
103Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68547760
104Pancreatic secretion_Homo sapiens_hsa049720.66676415
105Toll-like receptor signaling pathway_Homo sapiens_hsa046200.66102923
106Collecting duct acid secretion_Homo sapiens_hsa049660.66020166
107Leishmaniasis_Homo sapiens_hsa051400.65270317
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64571542
109Phototransduction_Homo sapiens_hsa047440.64453613
110RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.63736766
111Rheumatoid arthritis_Homo sapiens_hsa053230.63423578
112Influenza A_Homo sapiens_hsa051640.62492298
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.60758520
114Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60569736
115Acute myeloid leukemia_Homo sapiens_hsa052210.60195053
116Thyroid hormone synthesis_Homo sapiens_hsa049180.58623356
117FoxO signaling pathway_Homo sapiens_hsa040680.58173142
118VEGF signaling pathway_Homo sapiens_hsa043700.57852889
119Melanogenesis_Homo sapiens_hsa049160.57074267
120Tuberculosis_Homo sapiens_hsa051520.55596493
121Glycerolipid metabolism_Homo sapiens_hsa005610.55418835
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.53144837
123SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52644630
124Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51841893
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.48717563
126Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48185569
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48180360
128Pancreatic cancer_Homo sapiens_hsa052120.48090811
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48035463
130Dilated cardiomyopathy_Homo sapiens_hsa054140.47302372
131Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46001216
132Butanoate metabolism_Homo sapiens_hsa006500.44989017
133Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42662456
134Caffeine metabolism_Homo sapiens_hsa002320.39188211

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