RABGGTA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1indole-containing compound catabolic process (GO:0042436)4.62643571
2indolalkylamine catabolic process (GO:0046218)4.62643571
3tryptophan catabolic process (GO:0006569)4.62643571
4regulation of mitochondrial translation (GO:0070129)4.55631100
5tryptophan metabolic process (GO:0006568)4.42940982
6folic acid transport (GO:0015884)4.42044421
7aromatic amino acid family catabolic process (GO:0009074)4.34340388
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.29484624
9L-phenylalanine metabolic process (GO:0006558)4.29484624
10erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.16621273
11L-phenylalanine catabolic process (GO:0006559)4.16621273
12GDP-mannose metabolic process (GO:0019673)4.12874962
13rRNA modification (GO:0000154)3.98633784
14immunoglobulin mediated immune response (GO:0016064)3.96884125
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.95108770
16indolalkylamine metabolic process (GO:0006586)3.87687887
17glycine metabolic process (GO:0006544)3.84104700
18rRNA methylation (GO:0031167)3.81891249
19kynurenine metabolic process (GO:0070189)3.80116526
20ATP synthesis coupled proton transport (GO:0015986)3.79282155
21energy coupled proton transport, down electrochemical gradient (GO:0015985)3.79282155
22serine family amino acid catabolic process (GO:0009071)3.73378116
23sequestering of actin monomers (GO:0042989)3.61658134
24NADH metabolic process (GO:0006734)3.61400041
25triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.60410497
26regulation of oxidative phosphorylation (GO:0002082)3.59299483
27oligosaccharide catabolic process (GO:0009313)3.51939805
28ethanol oxidation (GO:0006069)3.50577742
29glyoxylate metabolic process (GO:0046487)3.50264029
30NIK/NF-kappaB signaling (GO:0038061)3.50136317
31serine family amino acid biosynthetic process (GO:0009070)3.48667591
32oxaloacetate metabolic process (GO:0006107)3.47398060
33viral transcription (GO:0019083)3.47068724
34DNA deamination (GO:0045006)3.44582977
35aromatic amino acid family metabolic process (GO:0009072)3.38680507
36serine family amino acid metabolic process (GO:0009069)3.38654226
37deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.35288959
38cysteine metabolic process (GO:0006534)3.34367767
39negative regulation of myeloid cell apoptotic process (GO:0033033)3.34013223
40L-methionine salvage (GO:0071267)3.31109866
41L-methionine biosynthetic process (GO:0071265)3.31109866
42amino acid salvage (GO:0043102)3.31109866
43proline metabolic process (GO:0006560)3.30779339
44high-density lipoprotein particle remodeling (GO:0034375)3.30485207
45cellular biogenic amine catabolic process (GO:0042402)3.28545422
46amine catabolic process (GO:0009310)3.28545422
47basic amino acid transport (GO:0015802)3.28219424
48sulfur amino acid catabolic process (GO:0000098)3.28040968
49ribosomal small subunit assembly (GO:0000028)3.24463297
50regulation of interferon-beta biosynthetic process (GO:0045357)3.23652627
51alpha-amino acid catabolic process (GO:1901606)3.22375139
52imidazole-containing compound metabolic process (GO:0052803)3.20935198
53regulation of B cell receptor signaling pathway (GO:0050855)3.16343289
54NAD biosynthetic process (GO:0009435)3.16328977
55urea metabolic process (GO:0019627)3.16312957
56urea cycle (GO:0000050)3.16312957
57amino sugar catabolic process (GO:0046348)3.16302472
58folic acid metabolic process (GO:0046655)3.13655892
59NAD metabolic process (GO:0019674)3.12896339
60regulation of cholesterol esterification (GO:0010872)3.12419927
61modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.12130218
62modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.12130218
63positive regulation by organism of defense response of other organism involved in symbiotic interact3.12130218
64modulation by symbiont of host immune response (GO:0052553)3.12130218
65positive regulation by symbiont of host defense response (GO:0052509)3.12130218
66modulation by symbiont of host defense response (GO:0052031)3.12130218
67translational termination (GO:0006415)3.10652165
68proteasome assembly (GO:0043248)3.10053145
69interferon-gamma production (GO:0032609)3.09546559
70respiratory electron transport chain (GO:0022904)3.08721741
71indole-containing compound metabolic process (GO:0042430)3.08631993
72SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.08354977
73viral protein processing (GO:0019082)3.08169838
74protein targeting to ER (GO:0045047)3.07351174
75positive regulation of protein homooligomerization (GO:0032464)3.05234946
76DNA double-strand break processing (GO:0000729)3.05204466
77negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.04754558
78detection of bacterium (GO:0016045)3.02056453
79cotranslational protein targeting to membrane (GO:0006613)3.01749682
80response to interferon-beta (GO:0035456)3.01405252
81protein complex biogenesis (GO:0070271)3.00356489
82electron transport chain (GO:0022900)3.00184300
83amino-acid betaine metabolic process (GO:0006577)2.99815901
84negative regulation of cholesterol transport (GO:0032375)2.99490386
85negative regulation of sterol transport (GO:0032372)2.99490386
86cytochrome complex assembly (GO:0017004)2.98886138
87coenzyme catabolic process (GO:0009109)2.98666212
88sulfur amino acid biosynthetic process (GO:0000097)2.96998242
89regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.96980288
90cellular amino acid catabolic process (GO:0009063)2.96362521
91leukocyte aggregation (GO:0070486)2.95809951
92protein localization to endoplasmic reticulum (GO:0070972)2.95765905
93L-serine metabolic process (GO:0006563)2.95127547
94mitochondrial respiratory chain complex assembly (GO:0033108)2.94866746
95proline biosynthetic process (GO:0006561)2.93804446
96translational elongation (GO:0006414)2.93547414
97nitrogen cycle metabolic process (GO:0071941)2.92683726
98methionine metabolic process (GO:0006555)2.91888454
99establishment of protein localization to endoplasmic reticulum (GO:0072599)2.90361676
100cellular response to interferon-beta (GO:0035458)2.89830786
101cellular response to interleukin-15 (GO:0071350)2.87795852
102pseudouridine synthesis (GO:0001522)2.86890229
103nucleobase biosynthetic process (GO:0046112)2.86363339
104response to peptidoglycan (GO:0032494)2.85951295
105fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.85753996
106formation of translation preinitiation complex (GO:0001731)2.85423645
107lysine metabolic process (GO:0006553)2.85213143
108lysine catabolic process (GO:0006554)2.85213143
109bile acid biosynthetic process (GO:0006699)2.84216514
110L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.83913597
111negative regulation of interleukin-12 production (GO:0032695)2.83723069
112fatty acid homeostasis (GO:0055089)2.82663162
113cellular response to type I interferon (GO:0071357)2.81642063
114type I interferon signaling pathway (GO:0060337)2.81642063
115regulation of inflammatory response to antigenic stimulus (GO:0002861)2.81541205
116homocysteine metabolic process (GO:0050667)2.81485771
117regulation of protein activation cascade (GO:2000257)2.80358840
118sulfur amino acid metabolic process (GO:0000096)2.79775838
119GTP biosynthetic process (GO:0006183)2.79658928
120complement activation, classical pathway (GO:0006958)2.77727615
121vitamin transport (GO:0051180)2.77622747
122B cell mediated immunity (GO:0019724)2.77259877
123myeloid dendritic cell differentiation (GO:0043011)2.76783469
124UTP biosynthetic process (GO:0006228)2.76424237
125negative regulation of cell killing (GO:0031342)2.75738614
126negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.75738614
127response to type I interferon (GO:0034340)2.74573056
128tRNA methylation (GO:0030488)2.72636612
129detection of other organism (GO:0098543)2.71739408
130ribosome biogenesis (GO:0042254)2.70575713
131mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.69435699
132viral life cycle (GO:0019058)2.69105226
133drug transport (GO:0015893)2.69006368
134negative regulation of innate immune response (GO:0045824)2.66956636
135fructose metabolic process (GO:0006000)2.66089010
136negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.65856558
137regulation of hypersensitivity (GO:0002883)2.65703241
138regulation of T cell tolerance induction (GO:0002664)2.65229879
139positive regulation of gamma-delta T cell activation (GO:0046645)2.64200833
140ribosomal small subunit biogenesis (GO:0042274)2.64169008
141mast cell activation involved in immune response (GO:0002279)2.63620065
142mast cell degranulation (GO:0043303)2.63620065
143macrophage activation involved in immune response (GO:0002281)2.63531574
144urate metabolic process (GO:0046415)2.63426955
145reverse cholesterol transport (GO:0043691)2.62580445
1462-oxoglutarate metabolic process (GO:0006103)2.62239708
147mitochondrial DNA replication (GO:0006264)2.61889729
148purine nucleobase biosynthetic process (GO:0009113)2.61833992
149antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.61796491
150antigen processing and presentation of endogenous antigen (GO:0019883)2.61033528
151mast cell activation (GO:0045576)2.60890108
152regulation of complement activation (GO:0030449)2.60768025
153respiratory burst (GO:0045730)2.60618737
154glucosamine-containing compound catabolic process (GO:1901072)2.60545092
155drug transmembrane transport (GO:0006855)2.59613033
156pyridine nucleotide biosynthetic process (GO:0019363)2.58321759
157nicotinamide nucleotide biosynthetic process (GO:0019359)2.58321759
158regulation of antigen processing and presentation (GO:0002577)2.57821480
159low-density lipoprotein particle remodeling (GO:0034374)2.57472423
160lymphocyte chemotaxis (GO:0048247)2.56813836
161regulation of bile acid biosynthetic process (GO:0070857)2.56272124
162positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.56006518
163methionine biosynthetic process (GO:0009086)2.55976765
164phospholipid efflux (GO:0033700)2.54505102
165valine metabolic process (GO:0006573)2.54245298
166guanosine-containing compound biosynthetic process (GO:1901070)2.53659082
167cofactor catabolic process (GO:0051187)2.53158176
168negative regulation of fibrinolysis (GO:0051918)2.52697566
169mannose metabolic process (GO:0006013)2.52540823
170myeloid dendritic cell activation (GO:0001773)2.50687046
171regulation of superoxide anion generation (GO:0032928)2.50293471
172UTP metabolic process (GO:0046051)2.49706814
173virion assembly (GO:0019068)2.47980567
174negative regulation of cytokine production involved in immune response (GO:0002719)2.47447607
175maturation of SSU-rRNA (GO:0030490)2.46269581
176GMP metabolic process (GO:0046037)2.43996990
177negative regulation of phagocytosis (GO:0050765)2.40969792
178antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.39758468
179mannosylation (GO:0097502)2.39362808
180T cell migration (GO:0072678)2.38745089
181pentose metabolic process (GO:0019321)2.38336252
182purine nucleoside triphosphate biosynthetic process (GO:0009145)2.36901730
183response to host immune response (GO:0052572)2.36349010
184response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.36349010
185pyrimidine nucleoside salvage (GO:0043097)2.36137199
186pyrimidine-containing compound salvage (GO:0008655)2.36137199
187positive regulation of antigen processing and presentation (GO:0002579)2.35525715
188negative thymic T cell selection (GO:0045060)2.34560955
189base-excision repair, AP site formation (GO:0006285)2.34107248
190hydrogen ion transmembrane transport (GO:1902600)2.33360567
191interferon-gamma-mediated signaling pathway (GO:0060333)2.31033337
192purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.30637236
193antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.30575380

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.82225764
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.58209808
3JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.28676225
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.05175480
5MYC_18555785_ChIP-Seq_MESCs_Mouse2.76713366
6CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.72211267
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.67126956
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.66977245
9RXR_22158963_ChIP-Seq_LIVER_Mouse2.59380085
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.59315986
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.54846171
12* PPARA_22158963_ChIP-Seq_LIVER_Mouse2.54102507
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.53291447
14E2F7_22180533_ChIP-Seq_HELA_Human2.44414752
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.43145802
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.38696902
17FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.35507953
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.35417018
19* EGR1_23403033_ChIP-Seq_LIVER_Mouse2.33127374
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.25465656
21PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.21877285
22FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.20406428
23TP63_17297297_ChIP-ChIP_HaCaT_Human2.18134395
24TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.16686738
25LXR_22292898_ChIP-Seq_THP-1_Human2.14804676
26SRF_21415370_ChIP-Seq_HL-1_Mouse2.14780224
27MYC_19079543_ChIP-ChIP_MESCs_Mouse2.08971372
28CREB1_15753290_ChIP-ChIP_HEK293T_Human2.08776801
29* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.05925515
30YY1_21170310_ChIP-Seq_MESCs_Mouse2.04401225
31THAP11_20581084_ChIP-Seq_MESCs_Mouse2.03372548
32* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.03009278
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.01982606
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.00649137
35BP1_19119308_ChIP-ChIP_Hs578T_Human1.95183154
36CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.93580743
37FOXP3_21729870_ChIP-Seq_TREG_Human1.93573017
38VDR_23849224_ChIP-Seq_CD4+_Human1.93117352
39IRF8_21731497_ChIP-ChIP_J774_Mouse1.92012061
40ELF1_20517297_ChIP-Seq_JURKAT_Human1.88949734
41* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.82064482
42POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.81888055
43* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.79222847
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78694609
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.78091307
46THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.72654671
47KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.72541399
48KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.72541399
49KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.72541399
50GABP_19822575_ChIP-Seq_HepG2_Human1.72003824
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.70855124
52RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.67546297
53NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.64283976
54CIITA_25753668_ChIP-Seq_RAJI_Human1.62038681
55XRN2_22483619_ChIP-Seq_HELA_Human1.60619409
56ZNF263_19887448_ChIP-Seq_K562_Human1.60525689
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.59774044
58BCOR_27268052_Chip-Seq_Bcells_Human1.59743547
59* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56672745
60* IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.56107833
61ELK3_25401928_ChIP-Seq_HUVEC_Human1.55850812
62P68_20966046_ChIP-Seq_HELA_Human1.54298980
63STAT4_19710469_ChIP-ChIP_TH1__Mouse1.53760901
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52822808
65* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.52536901
66MAF_26560356_Chip-Seq_TH2_Human1.52199448
67CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.51774527
68RARG_19884340_ChIP-ChIP_MEFs_Mouse1.49611609
69DCP1A_22483619_ChIP-Seq_HELA_Human1.47985079
70* MAF_26560356_Chip-Seq_TH1_Human1.47435000
71MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.44826084
72NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.43670917
73SA1_27219007_Chip-Seq_ERYTHROID_Human1.43489913
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42131483
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41440841
76* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.40190210
77LXR_22158963_ChIP-Seq_LIVER_Mouse1.40011040
78MYC_22102868_ChIP-Seq_BL_Human1.36684884
79MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.35586814
80PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.35499326
81HOXB4_20404135_ChIP-ChIP_EML_Mouse1.35451790
82TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35082424
83SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.35076685
84RACK7_27058665_Chip-Seq_MCF-7_Human1.32002377
85VDR_24763502_ChIP-Seq_THP-1_Human1.31319899
86UTX_26944678_Chip-Seq_JUKART_Human1.27955473
87POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.27166443
88SRY_22984422_ChIP-ChIP_TESTIS_Rat1.26711132
89SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26153160
90* CTCF_26484167_Chip-Seq_Bcells_Mouse1.25409871
91IRF1_19129219_ChIP-ChIP_H3396_Human1.25324643
92* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.23873626
93HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.23498974
94IRF8_22096565_ChIP-ChIP_GC-B_Human1.21917445
95E2F1_20622854_ChIP-Seq_HELA_Human1.20732330
96MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20353625
97SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20330718
98DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.19972300
99LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.19903830
100E2F4_17652178_ChIP-ChIP_JURKAT_Human1.19693020
101YY1_22570637_ChIP-Seq_MALME-3M_Human1.18687238
102RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.17455251
103PHF8_20622854_ChIP-Seq_HELA_Human1.15788696
104CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15631836
105YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14690474
106SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14360584
107STAT6_21828071_ChIP-Seq_BEAS2B_Human1.13993323
108TET1_21451524_ChIP-Seq_MESCs_Mouse1.13426374
109EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.12507539
110KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.12468785
111RUNX1_22412390_ChIP-Seq_EML_Mouse1.12007076
112* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11651193
113NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.11405105
114SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.10781613
115FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.10623318
116KDM5A_27292631_Chip-Seq_BREAST_Human1.09216006
117GATA1_22025678_ChIP-Seq_K562_Human1.09160007
118CTCF_27219007_Chip-Seq_ERYTHROID_Human1.09130855
119BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.08643527
120KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07969318
121SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.07886735
122E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.07850784
123CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07721583
124ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07361607
125STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.07107262
126NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.06901352
127* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05786898
128* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.05146052
129CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.04856922
130GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04329767
131KDM2B_26808549_Chip-Seq_SUP-B15_Human1.04260566
132FOXP1_21924763_ChIP-Seq_HESCs_Human1.04146807
133ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03910543
134P300_27268052_Chip-Seq_Bcells_Human1.03743180
135CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03619805
136NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.01971054
137BCL6_27268052_Chip-Seq_Bcells_Human1.01608025
138TTF2_22483619_ChIP-Seq_HELA_Human1.01444000
139MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00122106
140MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.98959243
141PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.97997501
142SPI1_23547873_ChIP-Seq_NB4_Human0.97245325
143RXRA_24833708_ChIP-Seq_LIVER_Mouse0.96894855
144SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.96520570
145ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.94827063
146* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.94141253
147VDR_21846776_ChIP-Seq_THP-1_Human0.93772851
148* LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.92516775
149* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.91957360

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.51342388
2MP0005360_urolithiasis4.29575543
3MP0003806_abnormal_nucleotide_metabolis4.10550238
4MP0005085_abnormal_gallbladder_physiolo3.64084401
5MP0008875_abnormal_xenobiotic_pharmacok3.57906158
6MP0005365_abnormal_bile_salt3.55331547
7MP0009840_abnormal_foam_cell2.61914588
8MP0002822_catalepsy2.38766373
9MP0010329_abnormal_lipoprotein_level2.37555652
10MP0005332_abnormal_amino_acid2.33810934
11MP0001764_abnormal_homeostasis2.32762326
12MP0004019_abnormal_vitamin_homeostasis2.26367011
13MP0005451_abnormal_body_composition2.14745394
14MP0002132_abnormal_respiratory_system2.04539620
15MP0005671_abnormal_response_to2.01358006
16MP0002138_abnormal_hepatobiliary_system1.98576845
17MP0005075_abnormal_melanosome_morpholog1.98101885
18MP0003195_calcinosis1.93619562
19MP0004510_myositis1.92768988
20MP0009697_abnormal_copulation1.90188232
21MP0003436_decreased_susceptibility_to1.87843217
22MP0001533_abnormal_skeleton_physiology1.87073627
23MP0006292_abnormal_olfactory_placode1.86022625
24MP0003763_abnormal_thymus_physiology1.77760840
25MP0002876_abnormal_thyroid_physiology1.68106667
26MP0008260_abnormal_autophagy1.67373151
27MP0003183_abnormal_peptide_metabolism1.64933524
28MP0000566_synostosis1.59547733
29MP0005310_abnormal_salivary_gland1.58725465
30MP0003186_abnormal_redox_activity1.57497916
31MP0001835_abnormal_antigen_presentation1.57217835
32MP0000609_abnormal_liver_physiology1.56961742
33MP0003303_peritoneal_inflammation1.55356312
34MP0006082_CNS_inflammation1.53212571
35MP0003693_abnormal_embryo_hatching1.50052504
36MP0001800_abnormal_humoral_immune1.49193394
37MP0002396_abnormal_hematopoietic_system1.48759297
38MP0000685_abnormal_immune_system1.42095192
39MP0001986_abnormal_taste_sensitivity1.40631105
40MP0002277_abnormal_respiratory_mucosa1.40049988
41MP0005319_abnormal_enzyme/_coenzyme1.39929645
42MP0002405_respiratory_system_inflammati1.37905038
43MP0006035_abnormal_mitochondrial_morpho1.36900988
44MP0009785_altered_susceptibility_to1.35982651
45MP0006036_abnormal_mitochondrial_physio1.32735143
46MP0004947_skin_inflammation1.30510837
47MP0005464_abnormal_platelet_physiology1.29837664
48MP0003075_altered_response_to1.26524379
49MP0008872_abnormal_physiological_respon1.26375600
50MP0000689_abnormal_spleen_morphology1.25974570
51MP0008058_abnormal_DNA_repair1.25546680
52MP0005083_abnormal_biliary_tract1.24448577
53MP0005584_abnormal_enzyme/coenzyme_acti1.24411392
54MP0005636_abnormal_mineral_homeostasis1.23762927
55MP0003252_abnormal_bile_duct1.23285802
56MP0008469_abnormal_protein_level1.22609923
57MP0009643_abnormal_urine_homeostasis1.19548396
58MP0005646_abnormal_pituitary_gland1.18907152
59MP0005058_abnormal_lysosome_morphology1.18704102
60MP0003866_abnormal_defecation1.18328673
61MP0002723_abnormal_immune_serum1.17720625
62MP0001873_stomach_inflammation1.17068809
63MP0002118_abnormal_lipid_homeostasis1.16479684
64MP0010155_abnormal_intestine_physiology1.15074032
65* MP0002398_abnormal_bone_marrow1.14526659
66MP0002722_abnormal_immune_system1.13964523
67MP0001666_abnormal_nutrient_absorption1.12153402
68MP0010094_abnormal_chromosome_stability1.12128771
69MP0009764_decreased_sensitivity_to1.11243507
70MP0005000_abnormal_immune_tolerance1.10359316
71MP0005025_abnormal_response_to1.10337971
72MP0002163_abnormal_gland_morphology1.09306372
73MP0001853_heart_inflammation1.06976636
74* MP0002420_abnormal_adaptive_immunity1.06604919
75* MP0001819_abnormal_immune_cell1.04949775
76MP0009278_abnormal_bone_marrow1.04589835
77MP0003718_maternal_effect1.04002384
78MP0001790_abnormal_immune_system1.03973182
79MP0005387_immune_system_phenotype1.03973182
80MP0003656_abnormal_erythrocyte_physiolo1.01206549
81MP0001845_abnormal_inflammatory_respons0.99652325
82MP0002452_abnormal_antigen_presenting0.99316705
83MP0003123_paternal_imprinting0.99187208
84MP0004381_abnormal_hair_follicle0.99160363
85MP0003172_abnormal_lysosome_physiology0.98628801
86MP0000716_abnormal_immune_system0.98209759
87MP0000358_abnormal_cell_content/0.97715552
88MP0004957_abnormal_blastocyst_morpholog0.97631566
89MP0000598_abnormal_liver_morphology0.96348627
90MP0000015_abnormal_ear_pigmentation0.95940459
91MP0000703_abnormal_thymus_morphology0.94537449
92MP0009763_increased_sensitivity_to0.93783187
93* MP0002429_abnormal_blood_cell0.93478065
94MP0000343_altered_response_to0.93077601
95MP0002419_abnormal_innate_immunity0.92978907
96MP0003122_maternal_imprinting0.92183476
97MP0002796_impaired_skin_barrier0.91951574
98MP0000490_abnormal_crypts_of0.90823591
99MP0009765_abnormal_xenobiotic_induced0.90352640
100MP0003077_abnormal_cell_cycle0.90339084
101MP0005397_hematopoietic_system_phenotyp0.89824996
102MP0001545_abnormal_hematopoietic_system0.89824996
103MP0002148_abnormal_hypersensitivity_rea0.89781001
104MP0002254_reproductive_system_inflammat0.89267174
105MP0002693_abnormal_pancreas_physiology0.88632162
106MP0008057_abnormal_DNA_replication0.87856355
107MP0005390_skeleton_phenotype0.87141018
108MP0000604_amyloidosis0.87121649
109MP0005084_abnormal_gallbladder_morpholo0.87106863
110MP0000858_altered_metastatic_potential0.87027105
111MP0005670_abnormal_white_adipose0.86610836
112MP0003879_abnormal_hair_cell0.86601174
113MP0005379_endocrine/exocrine_gland_phen0.86120919
114MP0005166_decreased_susceptibility_to0.85721369
115* MP0009642_abnormal_blood_homeostasis0.85597136
116MP0002736_abnormal_nociception_after0.83747886
117MP0009379_abnormal_foot_pigmentation0.83369413
118MP0003111_abnormal_nucleus_morphology0.82907588
119MP0008007_abnormal_cellular_replicative0.82637166
120MP0002933_joint_inflammation0.82231927
121MP0009333_abnormal_splenocyte_physiolog0.81829778
122MP0004133_heterotaxia0.81776324
123MP0004742_abnormal_vestibular_system0.79491095
124MP0001968_abnormal_touch/_nociception0.79022331
125MP0002136_abnormal_kidney_physiology0.74898492
126MP0005376_homeostasis/metabolism_phenot0.74696671
127MP0003453_abnormal_keratinocyte_physiol0.74122940
128MP0001756_abnormal_urination0.73961644
129MP0000538_abnormal_urinary_bladder0.73861818
130MP0003329_amyloid_beta_deposits0.73764871
131MP0005408_hypopigmentation0.73688881
132MP0005266_abnormal_metabolism0.73585676
133MP0003191_abnormal_cellular_cholesterol0.72404066
134MP0001216_abnormal_epidermal_layer0.72206002
135MP0003724_increased_susceptibility_to0.72023039
136MP0004142_abnormal_muscle_tone0.71977547
137MP0001727_abnormal_embryo_implantation0.70567616
138MP0002928_abnormal_bile_duct0.69663824
139MP0003448_altered_tumor_morphology0.69410934
140MP0000678_abnormal_parathyroid_gland0.67640659
141MP0005501_abnormal_skin_physiology0.65303584

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)4.40773305
2Abnormality of liposaccharide metabolism (HP:0010968)4.40773305
3Abnormality of glycosphingolipid metabolism (HP:0004343)4.40773305
4Abnormality of aromatic amino acid family metabolism (HP:0004338)4.03045099
5Abnormality of monocarboxylic acid metabolism (HP:0010996)4.01857587
6Abnormality of pyrimidine metabolism (HP:0004353)3.84775393
7Renal Fanconi syndrome (HP:0001994)3.63491737
8Abnormality of macrophages (HP:0004311)3.61992524
9Systemic lupus erythematosus (HP:0002725)3.52379735
10Increased hepatocellular lipid droplets (HP:0006565)3.44190158
11Recurrent bacterial skin infections (HP:0005406)3.41990301
12Increased intramyocellular lipid droplets (HP:0012240)3.41334784
13Hyperglycinemia (HP:0002154)3.37659821
14Intrahepatic cholestasis (HP:0001406)3.27937463
15Hyperglycinuria (HP:0003108)3.22391765
16Increased muscle lipid content (HP:0009058)3.16673033
17Eczematoid dermatitis (HP:0000976)3.12987927
18Hypobetalipoproteinemia (HP:0003563)3.12893158
19Gout (HP:0001997)3.12525612
20Lipid accumulation in hepatocytes (HP:0006561)3.11710485
21Complement deficiency (HP:0004431)3.08918261
22Xanthomatosis (HP:0000991)3.00591190
23Prolonged partial thromboplastin time (HP:0003645)2.98353457
24Recurrent abscess formation (HP:0002722)2.98349061
25Abnormality of serine family amino acid metabolism (HP:0010894)2.98329475
26Abnormality of glycine metabolism (HP:0010895)2.98329475
27Elevated erythrocyte sedimentation rate (HP:0003565)2.95609084
28Obstructive lung disease (HP:0006536)2.93335608
29Chronic obstructive pulmonary disease (HP:0006510)2.93335608
30Hyperammonemia (HP:0001987)2.91881542
31Mediastinal lymphadenopathy (HP:0100721)2.88514433
32Delayed CNS myelination (HP:0002188)2.82621904
33Exertional dyspnea (HP:0002875)2.78517329
34Abnormal number of erythroid precursors (HP:0012131)2.78093920
35IgM deficiency (HP:0002850)2.76297088
36Dry hair (HP:0011359)2.75845486
37Joint hemorrhage (HP:0005261)2.75309525
38Dysostosis multiplex (HP:0000943)2.74149484
39Abnormality of the lower motor neuron (HP:0002366)2.70641432
40Acute necrotizing encephalopathy (HP:0006965)2.67729001
41Abnormality of glutamine family amino acid metabolism (HP:0010902)2.64432791
42Ketosis (HP:0001946)2.60679453
43Abnormality of nucleobase metabolism (HP:0010932)2.60140149
44Deep venous thrombosis (HP:0002625)2.58131400
45Aplastic anemia (HP:0001915)2.57855774
46Vacuolated lymphocytes (HP:0001922)2.55422655
47Abnormality of complement system (HP:0005339)2.53326229
48Increased IgM level (HP:0003496)2.50993527
49Recurrent gram-negative bacterial infections (HP:0005420)2.48799446
50Stomatitis (HP:0010280)2.47984599
51Hyperlipoproteinemia (HP:0010980)2.47755667
52Lethargy (HP:0001254)2.47686725
533-Methylglutaconic aciduria (HP:0003535)2.46536614
54Conjugated hyperbilirubinemia (HP:0002908)2.45868967
55Abnormality of cells of the erythroid lineage (HP:0012130)2.45343605
56Progressive neurologic deterioration (HP:0002344)2.43911156
57Microvesicular hepatic steatosis (HP:0001414)2.42635978
58Hyperventilation (HP:0002883)2.41620386
59Myositis (HP:0100614)2.41587947
60Meningitis (HP:0001287)2.40260888
61Abnormality of aspartate family amino acid metabolism (HP:0010899)2.40239618
62Abnormality of fatty-acid metabolism (HP:0004359)2.40187367
63Recurrent skin infections (HP:0001581)2.39700633
64Abnormality of methionine metabolism (HP:0010901)2.39389434
65Ragged-red muscle fibers (HP:0003200)2.35828825
66Upper motor neuron abnormality (HP:0002127)2.32150937
67Purpura (HP:0000979)2.31816526
68Abnormality of sulfur amino acid metabolism (HP:0004339)2.27884991
69Increased serum ferritin (HP:0003281)2.27260685
70Abnormality of serum amino acid levels (HP:0003112)2.27205276
71Glomerulonephritis (HP:0000099)2.27038052
72Metabolic acidosis (HP:0001942)2.26397596
73Respiratory difficulties (HP:0002880)2.22590162
74Exercise intolerance (HP:0003546)2.21840420
75Hyperbilirubinemia (HP:0002904)2.20675972
76Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.19611690
77Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.18532527
78Dicarboxylic aciduria (HP:0003215)2.18170533
79Abnormality of dicarboxylic acid metabolism (HP:0010995)2.18170533
80Opisthotonus (HP:0002179)2.16825701
81Abnormality of mucopolysaccharide metabolism (HP:0011020)2.16474529
82Abnormality of polysaccharide metabolism (HP:0011012)2.16474529
83Abnormality of glycosaminoglycan metabolism (HP:0004371)2.16474529
84Abnormal delayed hypersensitivity skin test (HP:0002963)2.16197737
85Cerebral edema (HP:0002181)2.16103396
86Increased serum lactate (HP:0002151)2.14349844
87Megaloblastic anemia (HP:0001889)2.13343900
88Agammaglobulinemia (HP:0004432)2.13284104
89Decreased activity of mitochondrial respiratory chain (HP:0008972)2.13022918
90Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.13022918
91Ketoacidosis (HP:0001993)2.12683343
92Late onset (HP:0003584)2.09870021
93Lactic acidosis (HP:0003128)2.09370549
94Vasculitis (HP:0002633)2.08845658
95Oral leukoplakia (HP:0002745)2.08384957
96Pulmonary fibrosis (HP:0002206)2.06739303
97Abnormality of the common coagulation pathway (HP:0010990)2.06315201
98Increased purine levels (HP:0004368)2.06010371
99Hyperuricemia (HP:0002149)2.06010371
100Progressive macrocephaly (HP:0004481)2.05220699
101Type I transferrin isoform profile (HP:0003642)2.04516113
102Pancytopenia (HP:0001876)2.03222176
103Thyroid-stimulating hormone excess (HP:0002925)2.02853077
104Interstitial pulmonary disease (HP:0006530)2.02276650
105Fat malabsorption (HP:0002630)2.01674521
106Hepatic necrosis (HP:0002605)2.01549006
107Irritability (HP:0000737)2.01353590
108Anorexia (HP:0002039)2.01220563
109Recurrent fungal infections (HP:0002841)2.00728728
110Hepatocellular necrosis (HP:0001404)1.99247248
111Type 2 muscle fiber atrophy (HP:0003554)1.98684816
112Abnormality of purine metabolism (HP:0004352)1.97822526
113Renal tubular acidosis (HP:0001947)1.97554701
114Hypolipoproteinemia (HP:0010981)1.97319757
115Tongue fasciculations (HP:0001308)1.96764745
116Progressive muscle weakness (HP:0003323)1.96481477
117Urticaria (HP:0001025)1.96229002
118Acute encephalopathy (HP:0006846)1.95940095
119Respiratory failure (HP:0002878)1.95691845
120Poor suck (HP:0002033)1.95509101
121Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.95384368
122Loss of speech (HP:0002371)1.93299715
123Generalized aminoaciduria (HP:0002909)1.92645600
124Joint swelling (HP:0001386)1.92574151
125Prolonged neonatal jaundice (HP:0006579)1.92327198
126Abnormality of T cell physiology (HP:0011840)1.91587129
127Proximal tubulopathy (HP:0000114)1.91541420
128Petechiae (HP:0000967)1.91287560
129Reduced antithrombin III activity (HP:0001976)1.91002583
130Cerebral hypomyelination (HP:0006808)1.90424212
131Abnormality of iron homeostasis (HP:0011031)1.89849038
132Increased cerebral lipofuscin (HP:0011813)1.88269634
133Vomiting (HP:0002013)1.87663420
134Epiphyseal stippling (HP:0010655)1.86689921
135Hyperphosphaturia (HP:0003109)1.86413807
136Orchitis (HP:0100796)1.85819089
137Congenital ichthyosiform erythroderma (HP:0007431)1.84291110
138Hepatosplenomegaly (HP:0001433)1.84197128
139Reticulocytopenia (HP:0001896)1.84160058
140Pulmonary infiltrates (HP:0002113)1.84122066
141Abnormal mitochondria in muscle tissue (HP:0008316)1.83725100
142Hypertensive crisis (HP:0100735)1.83266184
143Emotional lability (HP:0000712)1.83217757
144Gangrene (HP:0100758)1.83093367
145Steatorrhea (HP:0002570)1.82767940
146Abnormality of renal resorption (HP:0011038)1.81927134
147Hypergammaglobulinemia (HP:0010702)1.81912837
148Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.81228611
149Muscle fibrillation (HP:0010546)1.80918722
150Increased neuronal autofluorescent lipopigment (HP:0002074)1.80416670
151Increased CSF lactate (HP:0002490)1.78075793
152Abnormality of lateral ventricle (HP:0030047)1.78017028
153Mucopolysacchariduria (HP:0008155)1.77894270
154Urinary glycosaminoglycan excretion (HP:0003541)1.77894270
155Recurrent cutaneous fungal infections (HP:0011370)1.77480755
156Chronic mucocutaneous candidiasis (HP:0002728)1.77480755
157Acute hepatic failure (HP:0006554)1.76875565
158Methylmalonic aciduria (HP:0012120)1.76672045
159Delusions (HP:0000746)1.75618437
160CNS demyelination (HP:0007305)1.74979831
161Retrobulbar optic neuritis (HP:0100654)1.74656329
162Optic neuritis (HP:0100653)1.74656329
163Agnosia (HP:0010524)1.73193915
164Impulsivity (HP:0100710)1.72503610
165Hypercholesterolemia (HP:0003124)1.72209960
166Brushfield spots (HP:0001088)1.71122330
167Hypoplasia of the thymus (HP:0000778)1.70653524
168Pustule (HP:0200039)1.68382548
169Mitochondrial inheritance (HP:0001427)1.68070615

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK197.12323395
2VRK23.22949596
3TSSK63.22893910
4MAP4K12.98692686
5TXK2.79381757
6STK162.59918905
7IRAK32.46665460
8MAP3K102.39887270
9ERN12.26678548
10TESK12.18680843
11DAPK12.17846133
12BCKDK2.15398668
13MAP3K122.14750592
14TRIB32.13819389
15PRPF4B2.12523428
16SIK32.12149313
17BUB12.01042125
18PINK12.00439641
19RIPK41.97795538
20ICK1.95083589
21PLK41.85334946
22TLK11.81088938
23CASK1.80658459
24GRK61.78614916
25FGFR41.68876484
26SMG11.67067193
27AKT31.64810678
28CCNB11.62341559
29MAP3K111.55967683
30ZAP701.48687974
31MAP2K31.47018898
32MAP2K61.42203160
33BTK1.41330181
34MAP2K21.36913985
35EPHB11.35870863
36WEE11.29684916
37EPHA41.27782790
38MAP2K71.26290147
39LMTK21.25317603
40ADRBK21.21934627
41PDK31.18501611
42PDK41.18501611
43VRK11.17798734
44GRK71.15126909
45IRAK41.10584948
46MST41.08355862
47MAP3K141.08341701
48TYK21.07995389
49NME11.06646863
50PASK1.05151759
51EPHA21.04575030
52KIT1.02265250
53PIM20.99287946
54EIF2AK10.97939343
55DAPK20.97039398
56LRRK20.91924966
57YES10.91564706
58NEK10.91069946
59ARAF0.90362068
60IKBKE0.85121497
61MAP2K40.84696012
62TEC0.84057942
63TAOK20.83823880
64ABL20.83190158
65SYK0.80880382
66MAPKAPK30.80766681
67MARK30.80006196
68SRPK10.77427923
69ACVR1B0.77069550
70KDR0.75471707
71ILK0.75044356
72TESK20.74568950
73MAP3K10.73086827
74SIK20.72455095
75PRKCI0.69910228
76TAOK10.69741250
77TAOK30.68681422
78TBK10.68328247
79NLK0.68122335
80IRAK10.67589230
81PRKG20.67346737
82RPS6KC10.64856573
83RPS6KL10.64856573
84DYRK30.64750425
85BRAF0.63857297
86JAK30.63204222
87BLK0.62317825
88HIPK20.61925621
89TNK20.61523577
90FLT30.59480283
91LYN0.58686435
92MAPK40.57742569
93HCK0.57403861
94NTRK30.57240419
95NME20.56963563
96IKBKB0.56741475
97MAPKAPK20.55607370
98CSF1R0.55496592
99MYLK0.55449395
100MAPK70.55270957
101MAPK110.55104920
102LCK0.54865155
103CDK70.54683574
104FES0.54482488
105RPS6KA50.54318937
106FGR0.54275716
107PHKG10.54224924
108PHKG20.54224924
109PTK2B0.53487319
110BRSK20.53323781
111ITK0.52459900
112PRKD20.51605759
113PDPK10.51589586
114PDK20.51032467
115CDC42BPA0.50688367
116SGK20.49396773
117DAPK30.48216485
118PTK60.48163134
119LIMK10.46839529
120EIF2AK30.46818109
121RPS6KA60.45530298
122PAK40.44329908
123MAPK120.44167750
124RPS6KA20.43525072
125PRKCG0.42873889
126PRKCD0.42707672
127PIM10.41735224
128FGFR30.41685320
129CDK80.40313138
130SGK30.39582029
131RPS6KA10.38998861
132PDK10.38941905
133PIK3CG0.38660285
134PLK10.38472154
135MAPK150.38361789
136JAK10.37241566
137STK100.36174991
138WNK30.34773280
139MAP3K40.33748150
140MAP3K30.33543394
141CSK0.33527460
142MATK0.32385649
143CSNK2A10.31106462
144CHUK0.30899538
145ZAK0.30442735
146BRSK10.29799557
147SIK10.29088645
148INSRR0.26931925

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.08848344
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.81611336
3Cyanoamino acid metabolism_Homo sapiens_hsa004602.68723060
4Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.66510455
5Allograft rejection_Homo sapiens_hsa053302.61741191
6Primary bile acid biosynthesis_Homo sapiens_hsa001202.56409767
7Autoimmune thyroid disease_Homo sapiens_hsa053202.47173485
8Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.39954860
9Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.32532298
10Graft-versus-host disease_Homo sapiens_hsa053322.32200732
11Type I diabetes mellitus_Homo sapiens_hsa049402.27756073
12Asthma_Homo sapiens_hsa053102.20681873
13Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.10525052
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.07599738
15Tryptophan metabolism_Homo sapiens_hsa003802.02353541
16Arginine biosynthesis_Homo sapiens_hsa002201.99334246
17Drug metabolism - other enzymes_Homo sapiens_hsa009831.99133714
18Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.98130819
19Cysteine and methionine metabolism_Homo sapiens_hsa002701.94138917
20Vitamin B6 metabolism_Homo sapiens_hsa007501.93629476
21Biosynthesis of amino acids_Homo sapiens_hsa012301.91518661
22beta-Alanine metabolism_Homo sapiens_hsa004101.90761464
23Rheumatoid arthritis_Homo sapiens_hsa053231.89511463
24Leishmaniasis_Homo sapiens_hsa051401.87233081
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.86701457
26Proteasome_Homo sapiens_hsa030501.83709313
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.81167723
28One carbon pool by folate_Homo sapiens_hsa006701.78292345
29Alzheimers disease_Homo sapiens_hsa050101.76708292
30Mismatch repair_Homo sapiens_hsa034301.75001655
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.74130618
32Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.71537791
33DNA replication_Homo sapiens_hsa030301.71407339
34Sulfur relay system_Homo sapiens_hsa041221.71014087
35Phenylalanine metabolism_Homo sapiens_hsa003601.70668704
36Complement and coagulation cascades_Homo sapiens_hsa046101.69018326
37Peroxisome_Homo sapiens_hsa041461.63027547
38Pyruvate metabolism_Homo sapiens_hsa006201.62561627
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.61298100
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.59768297
41Fatty acid degradation_Homo sapiens_hsa000711.58936499
42Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.57728501
43Huntingtons disease_Homo sapiens_hsa050161.57425513
44RNA polymerase_Homo sapiens_hsa030201.53188026
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.50295948
46Staphylococcus aureus infection_Homo sapiens_hsa051501.47595882
47Pentose and glucuronate interconversions_Homo sapiens_hsa000401.45225519
48Protein export_Homo sapiens_hsa030601.43987959
49Carbon metabolism_Homo sapiens_hsa012001.43539143
50Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.42355447
51Folate biosynthesis_Homo sapiens_hsa007901.42255942
52Toll-like receptor signaling pathway_Homo sapiens_hsa046201.41092567
53Selenocompound metabolism_Homo sapiens_hsa004501.36437577
54NF-kappa B signaling pathway_Homo sapiens_hsa040641.31798507
55Propanoate metabolism_Homo sapiens_hsa006401.30795931
56Pyrimidine metabolism_Homo sapiens_hsa002401.28813064
57Histidine metabolism_Homo sapiens_hsa003401.26789781
58Tyrosine metabolism_Homo sapiens_hsa003501.24888229
59Osteoclast differentiation_Homo sapiens_hsa043801.23166806
60Primary immunodeficiency_Homo sapiens_hsa053401.21957683
61Retinol metabolism_Homo sapiens_hsa008301.20240792
62Butanoate metabolism_Homo sapiens_hsa006501.20188619
63Viral myocarditis_Homo sapiens_hsa054161.20006646
64Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.18641444
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.16674092
66Vitamin digestion and absorption_Homo sapiens_hsa049771.13656423
67Chemical carcinogenesis_Homo sapiens_hsa052041.13076763
68Ribosome_Homo sapiens_hsa030101.12658131
69Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.09541356
70Steroid hormone biosynthesis_Homo sapiens_hsa001401.09228192
71Tuberculosis_Homo sapiens_hsa051521.05329493
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04446559
73Pentose phosphate pathway_Homo sapiens_hsa000301.04016473
74Systemic lupus erythematosus_Homo sapiens_hsa053221.02406170
75Phagosome_Homo sapiens_hsa041451.02281093
76Hematopoietic cell lineage_Homo sapiens_hsa046401.02104426
77Regulation of autophagy_Homo sapiens_hsa041401.01291792
78Herpes simplex infection_Homo sapiens_hsa051680.99550177
79Fructose and mannose metabolism_Homo sapiens_hsa000510.99003749
80Pertussis_Homo sapiens_hsa051330.98941178
81Arginine and proline metabolism_Homo sapiens_hsa003300.96436192
82Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.96309406
83Collecting duct acid secretion_Homo sapiens_hsa049660.95688066
84Fatty acid metabolism_Homo sapiens_hsa012120.94171041
85N-Glycan biosynthesis_Homo sapiens_hsa005100.92301761
86Sulfur metabolism_Homo sapiens_hsa009200.91343269
87Measles_Homo sapiens_hsa051620.88840021
88Nucleotide excision repair_Homo sapiens_hsa034200.86416092
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84147916
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82436004
91Base excision repair_Homo sapiens_hsa034100.82227179
92Toxoplasmosis_Homo sapiens_hsa051450.79745739
93Influenza A_Homo sapiens_hsa051640.77574899
94Synaptic vesicle cycle_Homo sapiens_hsa047210.76850127
95Salmonella infection_Homo sapiens_hsa051320.76338724
96Spliceosome_Homo sapiens_hsa030400.76017854
97Fatty acid elongation_Homo sapiens_hsa000620.73725437
98Epstein-Barr virus infection_Homo sapiens_hsa051690.72313933
99Caffeine metabolism_Homo sapiens_hsa002320.72193357
100Legionellosis_Homo sapiens_hsa051340.69116002
101Metabolic pathways_Homo sapiens_hsa011000.67945620
102RNA transport_Homo sapiens_hsa030130.67460972
103Cardiac muscle contraction_Homo sapiens_hsa042600.66499187
104Starch and sucrose metabolism_Homo sapiens_hsa005000.66123066
105B cell receptor signaling pathway_Homo sapiens_hsa046620.65116466
106RNA degradation_Homo sapiens_hsa030180.64464397
107Shigellosis_Homo sapiens_hsa051310.63887861
108ABC transporters_Homo sapiens_hsa020100.61996444
109T cell receptor signaling pathway_Homo sapiens_hsa046600.59526783
110Renin-angiotensin system_Homo sapiens_hsa046140.58849470
111TNF signaling pathway_Homo sapiens_hsa046680.58041388
112Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.57016239
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.55283685
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.55241476
115NOD-like receptor signaling pathway_Homo sapiens_hsa046210.55172780
116Glutathione metabolism_Homo sapiens_hsa004800.55023515
117PPAR signaling pathway_Homo sapiens_hsa033200.53975608
118SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53933555
119Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.53345319
120Homologous recombination_Homo sapiens_hsa034400.51797861
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.51161235
122African trypanosomiasis_Homo sapiens_hsa051430.50302462
123Oxidative phosphorylation_Homo sapiens_hsa001900.49609695
124Maturity onset diabetes of the young_Homo sapiens_hsa049500.49373721
125Purine metabolism_Homo sapiens_hsa002300.48105934
126Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.47459893
127Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46577800
128Arachidonic acid metabolism_Homo sapiens_hsa005900.44457845
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42450674
130Nitrogen metabolism_Homo sapiens_hsa009100.41520888
131Steroid biosynthesis_Homo sapiens_hsa001000.41096755
132Galactose metabolism_Homo sapiens_hsa000520.40813446
133alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.40668388
134Chemokine signaling pathway_Homo sapiens_hsa040620.39210118
135Malaria_Homo sapiens_hsa051440.38847983
136Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.38328915
137Sphingolipid metabolism_Homo sapiens_hsa006000.36762345
138Hepatitis C_Homo sapiens_hsa051600.35933206
139Glycerolipid metabolism_Homo sapiens_hsa005610.35208344
140Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.34749323
141Glycerophospholipid metabolism_Homo sapiens_hsa005640.34445614
142Bile secretion_Homo sapiens_hsa049760.34025047
143Notch signaling pathway_Homo sapiens_hsa043300.31517202
144RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31413052
145Intestinal immune network for IgA production_Homo sapiens_hsa046720.31282001
146Fat digestion and absorption_Homo sapiens_hsa049750.31197268
147Parkinsons disease_Homo sapiens_hsa050120.29971945
148Apoptosis_Homo sapiens_hsa042100.29939220
149Other glycan degradation_Homo sapiens_hsa005110.28102490
150Basal transcription factors_Homo sapiens_hsa030220.26552266
151Antigen processing and presentation_Homo sapiens_hsa046120.26483743
152Lysosome_Homo sapiens_hsa041420.26375243
153Vibrio cholerae infection_Homo sapiens_hsa051100.25819788
154Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22913053
155Fanconi anemia pathway_Homo sapiens_hsa034600.19856392

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