

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.58080275 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.93662806 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.93662806 |
| 4 | sequestering of actin monomers (GO:0042989) | 5.57853692 |
| 5 | DNA deamination (GO:0045006) | 4.95075180 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.64078422 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.50132677 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 4.44638348 |
| 9 | protein complex biogenesis (GO:0070271) | 4.40833982 |
| 10 | respiratory electron transport chain (GO:0022904) | 4.39618690 |
| 11 | electron transport chain (GO:0022900) | 4.32745007 |
| 12 | ribosomal small subunit assembly (GO:0000028) | 4.25490522 |
| 13 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.18062154 |
| 14 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.18062154 |
| 15 | NADH dehydrogenase complex assembly (GO:0010257) | 4.18062154 |
| 16 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.86619643 |
| 17 | cytidine deamination (GO:0009972) | 3.78703332 |
| 18 | cytidine metabolic process (GO:0046087) | 3.78703332 |
| 19 | cytidine catabolic process (GO:0006216) | 3.78703332 |
| 20 | viral transcription (GO:0019083) | 3.74852905 |
| 21 | platelet dense granule organization (GO:0060155) | 3.72742214 |
| 22 | translational termination (GO:0006415) | 3.63560494 |
| 23 | protein localization to cilium (GO:0061512) | 3.55786231 |
| 24 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.45042517 |
| 25 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.43696379 |
| 26 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.43696379 |
| 27 | iron-sulfur cluster assembly (GO:0016226) | 3.42567160 |
| 28 | metallo-sulfur cluster assembly (GO:0031163) | 3.42567160 |
| 29 | cotranslational protein targeting to membrane (GO:0006613) | 3.41915143 |
| 30 | protein-cofactor linkage (GO:0018065) | 3.36744395 |
| 31 | protein targeting to ER (GO:0045047) | 3.35931706 |
| 32 | ATP biosynthetic process (GO:0006754) | 3.28183337 |
| 33 | protein neddylation (GO:0045116) | 3.26711669 |
| 34 | hydrogen ion transmembrane transport (GO:1902600) | 3.26530251 |
| 35 | translational elongation (GO:0006414) | 3.23806427 |
| 36 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.19832115 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.19725291 |
| 38 | protein localization to endoplasmic reticulum (GO:0070972) | 3.19394413 |
| 39 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.18108900 |
| 40 | proteasome assembly (GO:0043248) | 3.14923166 |
| 41 | proton transport (GO:0015992) | 3.12480547 |
| 42 | hydrogen transport (GO:0006818) | 3.08771735 |
| 43 | regulation of activation of Janus kinase activity (GO:0010533) | 3.08225967 |
| 44 | mannosylation (GO:0097502) | 3.07650122 |
| 45 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.04287424 |
| 46 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.03391927 |
| 47 | GPI anchor metabolic process (GO:0006505) | 3.03388176 |
| 48 | GPI anchor biosynthetic process (GO:0006506) | 3.02044930 |
| 49 | behavioral response to nicotine (GO:0035095) | 3.00179489 |
| 50 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.98680924 |
| 51 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.97659694 |
| 52 | anterograde synaptic vesicle transport (GO:0048490) | 2.95498446 |
| 53 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.95016852 |
| 54 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.91545695 |
| 55 | negative regulation of heart rate (GO:0010459) | 2.90664510 |
| 56 | maturation of SSU-rRNA (GO:0030490) | 2.86905748 |
| 57 | viral life cycle (GO:0019058) | 2.85974647 |
| 58 | spliceosomal complex assembly (GO:0000245) | 2.83453672 |
| 59 | negative regulation of mast cell activation (GO:0033004) | 2.83032578 |
| 60 | DNA damage response, detection of DNA damage (GO:0042769) | 2.77633076 |
| 61 | negative regulation of telomere maintenance (GO:0032205) | 2.75307243 |
| 62 | termination of RNA polymerase III transcription (GO:0006386) | 2.75108570 |
| 63 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.75108570 |
| 64 | cellular protein complex disassembly (GO:0043624) | 2.73432578 |
| 65 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.69155800 |
| 66 | neuron fate determination (GO:0048664) | 2.65415499 |
| 67 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.64303049 |
| 68 | organelle disassembly (GO:1903008) | 2.63802274 |
| 69 | respiratory chain complex IV assembly (GO:0008535) | 2.61295701 |
| 70 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.60340087 |
| 71 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.60340087 |
| 72 | cytochrome complex assembly (GO:0017004) | 2.57135199 |
| 73 | translational initiation (GO:0006413) | 2.56437885 |
| 74 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.55164227 |
| 75 | neural tube formation (GO:0001841) | 2.53103973 |
| 76 | inner mitochondrial membrane organization (GO:0007007) | 2.52537421 |
| 77 | ribonucleoprotein complex disassembly (GO:0032988) | 2.50943832 |
| 78 | translation (GO:0006412) | 2.48995086 |
| 79 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.46991698 |
| 80 | spliceosomal snRNP assembly (GO:0000387) | 2.46919174 |
| 81 | rRNA modification (GO:0000154) | 2.45810384 |
| 82 | regulation of cilium movement (GO:0003352) | 2.45792633 |
| 83 | actin nucleation (GO:0045010) | 2.44909318 |
| 84 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.41381793 |
| 85 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.40750452 |
| 86 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.40747139 |
| 87 | spinal cord association neuron differentiation (GO:0021527) | 2.39868083 |
| 88 | oxidative phosphorylation (GO:0006119) | 2.36908937 |
| 89 | epithelial cilium movement (GO:0003351) | 2.35155588 |
| 90 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.33017197 |
| 91 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.32921077 |
| 92 | base-excision repair, AP site formation (GO:0006285) | 2.32348125 |
| 93 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.31558434 |
| 94 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.31325416 |
| 95 | synaptic transmission, cholinergic (GO:0007271) | 2.30992987 |
| 96 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.30866235 |
| 97 | intracellular protein transmembrane import (GO:0044743) | 2.29723349 |
| 98 | negative regulation by host of viral transcription (GO:0043922) | 2.29001191 |
| 99 | positive regulation of prostaglandin secretion (GO:0032308) | 2.28114201 |
| 100 | histone mRNA metabolic process (GO:0008334) | 2.27983974 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.87032703 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.74124121 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.31986511 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.29906477 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.27586679 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.08294113 |
| 7 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.02426864 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.71518457 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.50004777 |
| 10 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.41674911 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.40072314 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38690424 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.35883239 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.35221340 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.32242995 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.29595904 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.14497483 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.02013371 |
| 19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.95408960 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.94285066 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.88734572 |
| 22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.86726348 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.86268404 |
| 24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.84806165 |
| 25 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.80843769 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.79472489 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.78693197 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.76527823 |
| 29 | FUS_26573619_Chip-Seq_HEK293_Human | 1.73879330 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.70188764 |
| 31 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.65905643 |
| 32 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63662498 |
| 33 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.61439304 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.55460395 |
| 35 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.53689054 |
| 36 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.53206879 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.52108237 |
| 38 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.46327761 |
| 39 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.44504716 |
| 40 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.41025375 |
| 41 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.39032308 |
| 42 | P300_19829295_ChIP-Seq_ESCs_Human | 1.38571562 |
| 43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.38067077 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.36824880 |
| 45 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.35752444 |
| 46 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.35041880 |
| 47 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34777491 |
| 48 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.28854321 |
| 49 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.25925833 |
| 50 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.25676410 |
| 51 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.25261509 |
| 52 | AR_20517297_ChIP-Seq_VCAP_Human | 1.22505912 |
| 53 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.21470251 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20762475 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20762475 |
| 56 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.20325411 |
| 57 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.19103716 |
| 58 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.15466654 |
| 59 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14602835 |
| 60 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14602835 |
| 61 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.12984565 |
| 62 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12430072 |
| 63 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11707022 |
| 64 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.11570454 |
| 65 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.11457088 |
| 66 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.11114959 |
| 67 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08349377 |
| 68 | GATA3_26560356_Chip-Seq_TH2_Human | 1.07953473 |
| 69 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.07883437 |
| 70 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07445978 |
| 71 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.07232526 |
| 72 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.07164405 |
| 73 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06654516 |
| 74 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.05997045 |
| 75 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.05976532 |
| 76 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03470342 |
| 77 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.03221790 |
| 78 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02758807 |
| 79 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.01527958 |
| 80 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.01367890 |
| 81 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.01189269 |
| 82 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.99373693 |
| 83 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97037087 |
| 84 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97037087 |
| 85 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.94021635 |
| 86 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.93990479 |
| 87 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91574109 |
| 88 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90175819 |
| 89 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.89856926 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88623614 |
| 91 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86641860 |
| 92 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.86045080 |
| 93 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.83917723 |
| 94 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.83353291 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.83188352 |
| 96 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.83181108 |
| 97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.82811260 |
| 98 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.82569736 |
| 99 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.82107966 |
| 100 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.81725647 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 3.04571430 |
| 2 | MP0002277_abnormal_respiratory_mucosa | 3.02129093 |
| 3 | MP0002102_abnormal_ear_morphology | 3.00668514 |
| 4 | MP0003880_abnormal_central_pattern | 2.98027020 |
| 5 | MP0001529_abnormal_vocalization | 2.90316994 |
| 6 | MP0009379_abnormal_foot_pigmentation | 2.89871565 |
| 7 | MP0005084_abnormal_gallbladder_morpholo | 2.63070794 |
| 8 | MP0006292_abnormal_olfactory_placode | 2.41701451 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.40120158 |
| 10 | MP0008995_early_reproductive_senescence | 2.00736862 |
| 11 | MP0003724_increased_susceptibility_to | 1.89382866 |
| 12 | MP0004147_increased_porphyrin_level | 1.88394370 |
| 13 | MP0004142_abnormal_muscle_tone | 1.85368733 |
| 14 | MP0009785_altered_susceptibility_to | 1.83617763 |
| 15 | MP0002653_abnormal_ependyma_morphology | 1.78517183 |
| 16 | MP0004133_heterotaxia | 1.76710254 |
| 17 | MP0001835_abnormal_antigen_presentation | 1.76308610 |
| 18 | MP0005645_abnormal_hypothalamus_physiol | 1.72604014 |
| 19 | MP0003011_delayed_dark_adaptation | 1.71563595 |
| 20 | MP0008058_abnormal_DNA_repair | 1.68367277 |
| 21 | MP0006276_abnormal_autonomic_nervous | 1.67868899 |
| 22 | MP0002928_abnormal_bile_duct | 1.67154088 |
| 23 | MP0003136_yellow_coat_color | 1.61486134 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.61173938 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.56265613 |
| 26 | MP0001905_abnormal_dopamine_level | 1.50793540 |
| 27 | MP0005253_abnormal_eye_physiology | 1.46986041 |
| 28 | MP0002736_abnormal_nociception_after | 1.41518061 |
| 29 | MP0002735_abnormal_chemical_nociception | 1.36790008 |
| 30 | MP0008875_abnormal_xenobiotic_pharmacok | 1.34894254 |
| 31 | MP0001800_abnormal_humoral_immune | 1.31651924 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.31127674 |
| 33 | MP0002822_catalepsy | 1.29279965 |
| 34 | MP0005377_hearing/vestibular/ear_phenot | 1.27662821 |
| 35 | MP0003878_abnormal_ear_physiology | 1.27662821 |
| 36 | MP0004145_abnormal_muscle_electrophysio | 1.26523843 |
| 37 | MP0001984_abnormal_olfaction | 1.24960608 |
| 38 | MP0002095_abnormal_skin_pigmentation | 1.24857209 |
| 39 | MP0002132_abnormal_respiratory_system | 1.24728381 |
| 40 | MP0000631_abnormal_neuroendocrine_gland | 1.23945200 |
| 41 | MP0001486_abnormal_startle_reflex | 1.23319332 |
| 42 | MP0003938_abnormal_ear_development | 1.21997446 |
| 43 | MP0005394_taste/olfaction_phenotype | 1.21422601 |
| 44 | MP0005499_abnormal_olfactory_system | 1.21422601 |
| 45 | MP0000372_irregular_coat_pigmentation | 1.19177104 |
| 46 | MP0001485_abnormal_pinna_reflex | 1.18614348 |
| 47 | MP0009745_abnormal_behavioral_response | 1.17539991 |
| 48 | MP0002148_abnormal_hypersensitivity_rea | 1.17447933 |
| 49 | MP0002272_abnormal_nervous_system | 1.16173456 |
| 50 | MP0001188_hyperpigmentation | 1.14352679 |
| 51 | MP0009764_decreased_sensitivity_to | 1.12018622 |
| 52 | MP0004742_abnormal_vestibular_system | 1.11750108 |
| 53 | MP0002876_abnormal_thyroid_physiology | 1.10668295 |
| 54 | MP0003122_maternal_imprinting | 1.10098305 |
| 55 | MP0003866_abnormal_defecation | 1.09249276 |
| 56 | MP0003567_abnormal_fetal_cardiomyocyte | 1.08030502 |
| 57 | MP0002723_abnormal_immune_serum | 1.08016516 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.06511501 |
| 59 | MP0001986_abnormal_taste_sensitivity | 1.06462697 |
| 60 | MP0002638_abnormal_pupillary_reflex | 1.04832658 |
| 61 | MP0002751_abnormal_autonomic_nervous | 1.04601245 |
| 62 | MP0005075_abnormal_melanosome_morpholog | 1.00520069 |
| 63 | MP0005000_abnormal_immune_tolerance | 0.98355360 |
| 64 | MP0000026_abnormal_inner_ear | 0.97542513 |
| 65 | MP0001970_abnormal_pain_threshold | 0.95989908 |
| 66 | MP0000566_synostosis | 0.94988592 |
| 67 | MP0002452_abnormal_antigen_presenting | 0.94920530 |
| 68 | MP0002938_white_spotting | 0.94496984 |
| 69 | MP0001293_anophthalmia | 0.92430521 |
| 70 | MP0008872_abnormal_physiological_respon | 0.91172579 |
| 71 | MP0000465_gastrointestinal_hemorrhage | 0.90534957 |
| 72 | MP0001819_abnormal_immune_cell | 0.90045207 |
| 73 | MP0001324_abnormal_eye_pigmentation | 0.89562156 |
| 74 | MP0002420_abnormal_adaptive_immunity | 0.88345887 |
| 75 | MP0002064_seizures | 0.87173468 |
| 76 | MP0002282_abnormal_trachea_morphology | 0.86994809 |
| 77 | MP0002752_abnormal_somatic_nervous | 0.86987042 |
| 78 | MP0005025_abnormal_response_to | 0.86772714 |
| 79 | MP0002067_abnormal_sensory_capabilities | 0.86318112 |
| 80 | MP0003186_abnormal_redox_activity | 0.85530400 |
| 81 | MP0001790_abnormal_immune_system | 0.84533304 |
| 82 | MP0005387_immune_system_phenotype | 0.84533304 |
| 83 | MP0002572_abnormal_emotion/affect_behav | 0.84401569 |
| 84 | MP0006082_CNS_inflammation | 0.82405798 |
| 85 | MP0005085_abnormal_gallbladder_physiolo | 0.82152200 |
| 86 | MP0003786_premature_aging | 0.81272963 |
| 87 | MP0005167_abnormal_blood-brain_barrier | 0.79590936 |
| 88 | MP0005195_abnormal_posterior_eye | 0.79360697 |
| 89 | MP0000647_abnormal_sebaceous_gland | 0.77456062 |
| 90 | MP0010386_abnormal_urinary_bladder | 0.76802126 |
| 91 | MP0002234_abnormal_pharynx_morphology | 0.76091030 |
| 92 | MP0000685_abnormal_immune_system | 0.76088962 |
| 93 | MP0006035_abnormal_mitochondrial_morpho | 0.75301752 |
| 94 | MP0000778_abnormal_nervous_system | 0.75133394 |
| 95 | MP0005646_abnormal_pituitary_gland | 0.72445283 |
| 96 | MP0001346_abnormal_lacrimal_gland | 0.72404517 |
| 97 | MP0002734_abnormal_mechanical_nocicepti | 0.71286874 |
| 98 | MP0009046_muscle_twitch | 0.70929703 |
| 99 | MP0002733_abnormal_thermal_nociception | 0.70910171 |
| 100 | MP0008877_abnormal_DNA_methylation | 0.69115879 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.58788095 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.19726359 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.06087344 |
| 4 | Acute encephalopathy (HP:0006846) | 3.79902329 |
| 5 | 3-Methylglutaconic aciduria (HP:0003535) | 3.77733693 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.75047695 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.59255878 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.50632953 |
| 9 | Increased CSF lactate (HP:0002490) | 3.48717722 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.27335899 |
| 11 | Type II lissencephaly (HP:0007260) | 3.19821746 |
| 12 | Pancreatic cysts (HP:0001737) | 3.13168884 |
| 13 | True hermaphroditism (HP:0010459) | 2.97947855 |
| 14 | Hepatic necrosis (HP:0002605) | 2.97793597 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 2.94237180 |
| 16 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.90924095 |
| 17 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.90924095 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 2.87660536 |
| 19 | Congenital, generalized hypertrichosis (HP:0004540) | 2.85822017 |
| 20 | Cerebral edema (HP:0002181) | 2.85552108 |
| 21 | Medial flaring of the eyebrow (HP:0010747) | 2.84299028 |
| 22 | Abolished electroretinogram (ERG) (HP:0000550) | 2.78487126 |
| 23 | Aplastic anemia (HP:0001915) | 2.67712083 |
| 24 | Pancreatic fibrosis (HP:0100732) | 2.64523807 |
| 25 | Cerebellar dysplasia (HP:0007033) | 2.60849446 |
| 26 | Retinal dysplasia (HP:0007973) | 2.60057319 |
| 27 | Optic disc pallor (HP:0000543) | 2.55438069 |
| 28 | Type 2 muscle fiber atrophy (HP:0003554) | 2.52622272 |
| 29 | Exertional dyspnea (HP:0002875) | 2.52355623 |
| 30 | Severe combined immunodeficiency (HP:0004430) | 2.50552520 |
| 31 | Increased muscle lipid content (HP:0009058) | 2.47819775 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.45308057 |
| 33 | Gait imbalance (HP:0002141) | 2.45224750 |
| 34 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.40006334 |
| 35 | Molar tooth sign on MRI (HP:0002419) | 2.38267279 |
| 36 | Abnormality of midbrain morphology (HP:0002418) | 2.38267279 |
| 37 | Congenital primary aphakia (HP:0007707) | 2.37229576 |
| 38 | Septo-optic dysplasia (HP:0100842) | 2.35300850 |
| 39 | Congenital stationary night blindness (HP:0007642) | 2.31407583 |
| 40 | Nephrogenic diabetes insipidus (HP:0009806) | 2.31324383 |
| 41 | Hypoproteinemia (HP:0003075) | 2.30396793 |
| 42 | Nephronophthisis (HP:0000090) | 2.30021205 |
| 43 | IgG deficiency (HP:0004315) | 2.27005387 |
| 44 | Reticulocytopenia (HP:0001896) | 2.26651500 |
| 45 | Hypothermia (HP:0002045) | 2.24997796 |
| 46 | B lymphocytopenia (HP:0010976) | 2.24243514 |
| 47 | Abnormality of B cell number (HP:0010975) | 2.22924745 |
| 48 | Decreased central vision (HP:0007663) | 2.21529133 |
| 49 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.20693452 |
| 50 | Lactic acidosis (HP:0003128) | 2.20454247 |
| 51 | Increased serum lactate (HP:0002151) | 2.18161952 |
| 52 | Methylmalonic acidemia (HP:0002912) | 2.14093938 |
| 53 | Panhypogammaglobulinemia (HP:0003139) | 2.13713974 |
| 54 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.13514132 |
| 55 | Muscle fiber atrophy (HP:0100295) | 2.12857977 |
| 56 | Lissencephaly (HP:0001339) | 2.11983552 |
| 57 | Stomatitis (HP:0010280) | 2.11421184 |
| 58 | Rib fusion (HP:0000902) | 2.08487616 |
| 59 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.05663986 |
| 60 | Pendular nystagmus (HP:0012043) | 2.02489140 |
| 61 | Focal motor seizures (HP:0011153) | 2.01664473 |
| 62 | Pallor (HP:0000980) | 2.01435081 |
| 63 | Leukodystrophy (HP:0002415) | 1.99261002 |
| 64 | Attenuation of retinal blood vessels (HP:0007843) | 1.99227991 |
| 65 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.97907738 |
| 66 | Sclerocornea (HP:0000647) | 1.93215692 |
| 67 | Hypoplasia of the pons (HP:0012110) | 1.93124862 |
| 68 | Abnormality of the pons (HP:0007361) | 1.93081952 |
| 69 | Abnormality of the prostate (HP:0008775) | 1.92938719 |
| 70 | Generalized aminoaciduria (HP:0002909) | 1.92423250 |
| 71 | Abnormality of renal resorption (HP:0011038) | 1.92369812 |
| 72 | Macrocytic anemia (HP:0001972) | 1.89104731 |
| 73 | Respiratory difficulties (HP:0002880) | 1.87911042 |
| 74 | Exercise intolerance (HP:0003546) | 1.87604688 |
| 75 | Polyphagia (HP:0002591) | 1.87586803 |
| 76 | Abnormality of the renal medulla (HP:0100957) | 1.87454203 |
| 77 | Respiratory failure (HP:0002878) | 1.86112938 |
| 78 | Limb dystonia (HP:0002451) | 1.84673006 |
| 79 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.83998563 |
| 80 | Short tibia (HP:0005736) | 1.82953776 |
| 81 | Hypochromic microcytic anemia (HP:0004840) | 1.81947190 |
| 82 | Lethargy (HP:0001254) | 1.79830845 |
| 83 | Increased IgM level (HP:0003496) | 1.78364598 |
| 84 | Myokymia (HP:0002411) | 1.77617871 |
| 85 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.77233664 |
| 86 | Vaginal atresia (HP:0000148) | 1.76731808 |
| 87 | Thyroid-stimulating hormone excess (HP:0002925) | 1.76689279 |
| 88 | Microvesicular hepatic steatosis (HP:0001414) | 1.76166466 |
| 89 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.75851347 |
| 90 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.75280665 |
| 91 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.75280665 |
| 92 | Combined immunodeficiency (HP:0005387) | 1.74723190 |
| 93 | Cystic liver disease (HP:0006706) | 1.74571977 |
| 94 | Concave nail (HP:0001598) | 1.73449443 |
| 95 | Tubulointerstitial nephritis (HP:0001970) | 1.73005472 |
| 96 | Anencephaly (HP:0002323) | 1.72997974 |
| 97 | Methylmalonic aciduria (HP:0012120) | 1.72260104 |
| 98 | Poor suck (HP:0002033) | 1.72047023 |
| 99 | Delayed CNS myelination (HP:0002188) | 1.70854513 |
| 100 | Growth hormone deficiency (HP:0000824) | 1.69996181 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.61465108 |
| 2 | TXK | 3.06156868 |
| 3 | CDK19 | 2.96121001 |
| 4 | ZAK | 2.39267659 |
| 5 | BCKDK | 2.34015447 |
| 6 | TSSK6 | 2.19175417 |
| 7 | VRK2 | 2.18696444 |
| 8 | DYRK2 | 2.18106576 |
| 9 | TESK2 | 2.17415082 |
| 10 | SRPK1 | 2.16959209 |
| 11 | VRK1 | 2.16227458 |
| 12 | MAPK15 | 2.15272498 |
| 13 | TRIM28 | 2.11218326 |
| 14 | TAOK3 | 2.10621582 |
| 15 | ADRBK2 | 2.03798393 |
| 16 | WNK3 | 1.98259981 |
| 17 | TIE1 | 1.94935842 |
| 18 | TLK1 | 1.80523575 |
| 19 | MAP3K12 | 1.76395378 |
| 20 | BMPR2 | 1.71168743 |
| 21 | PINK1 | 1.69640880 |
| 22 | BCR | 1.62803844 |
| 23 | KDR | 1.62573370 |
| 24 | MAPK13 | 1.51833098 |
| 25 | MAP2K7 | 1.50110123 |
| 26 | GRK1 | 1.49808063 |
| 27 | DYRK3 | 1.43780464 |
| 28 | MAP3K4 | 1.43709059 |
| 29 | WNK4 | 1.29880268 |
| 30 | MARK1 | 1.29147937 |
| 31 | INSRR | 1.23405637 |
| 32 | NUAK1 | 1.21850074 |
| 33 | NME1 | 1.20783735 |
| 34 | MAP4K1 | 1.14043047 |
| 35 | GRK7 | 1.11385850 |
| 36 | MATK | 1.08467313 |
| 37 | CAMKK2 | 1.05380939 |
| 38 | FES | 1.04366749 |
| 39 | BMPR1B | 1.02968757 |
| 40 | RPS6KA5 | 1.02912842 |
| 41 | ERBB3 | 1.01767079 |
| 42 | CDK8 | 0.97979360 |
| 43 | CSNK1G3 | 0.95754864 |
| 44 | STK16 | 0.95557027 |
| 45 | RPS6KA4 | 0.94871515 |
| 46 | LIMK1 | 0.91781479 |
| 47 | CSNK1G2 | 0.90666135 |
| 48 | SYK | 0.89099348 |
| 49 | EPHA3 | 0.86653667 |
| 50 | MST4 | 0.78568962 |
| 51 | LYN | 0.75423093 |
| 52 | MARK3 | 0.75274888 |
| 53 | CSNK1A1L | 0.68294308 |
| 54 | OXSR1 | 0.67995420 |
| 55 | TEC | 0.67582840 |
| 56 | RIPK4 | 0.65843847 |
| 57 | PRKCE | 0.65410358 |
| 58 | ITK | 0.64308104 |
| 59 | GRK6 | 0.64068802 |
| 60 | LCK | 0.63897803 |
| 61 | BLK | 0.63538471 |
| 62 | CSF1R | 0.62279267 |
| 63 | IRAK4 | 0.62066187 |
| 64 | CSNK1G1 | 0.60062134 |
| 65 | MAP3K5 | 0.59527957 |
| 66 | MUSK | 0.58735946 |
| 67 | IKBKB | 0.58194653 |
| 68 | PRKCQ | 0.57872524 |
| 69 | PLK4 | 0.55712806 |
| 70 | CCNB1 | 0.55505987 |
| 71 | PIM1 | 0.54075192 |
| 72 | UHMK1 | 0.54073495 |
| 73 | ADRBK1 | 0.52787418 |
| 74 | CASK | 0.52257877 |
| 75 | MINK1 | 0.50630864 |
| 76 | CSNK2A2 | 0.49218442 |
| 77 | EIF2AK3 | 0.48767942 |
| 78 | CSNK2A1 | 0.45739006 |
| 79 | BTK | 0.44863965 |
| 80 | PRKCG | 0.44862709 |
| 81 | PRKG1 | 0.44312590 |
| 82 | KIT | 0.43935025 |
| 83 | PAK3 | 0.43043650 |
| 84 | PRKACA | 0.42246056 |
| 85 | EPHA4 | 0.41077939 |
| 86 | DYRK1B | 0.40838084 |
| 87 | OBSCN | 0.40561524 |
| 88 | TESK1 | 0.39247392 |
| 89 | CAMK2A | 0.39174251 |
| 90 | MAP2K4 | 0.38395499 |
| 91 | CDK14 | 0.37125188 |
| 92 | PLK3 | 0.36769976 |
| 93 | DYRK1A | 0.35750082 |
| 94 | IKBKE | 0.35637308 |
| 95 | ATR | 0.32396345 |
| 96 | CSK | 0.32389167 |
| 97 | IGF1R | 0.31961153 |
| 98 | PLK2 | 0.31945797 |
| 99 | CAMK1 | 0.31888535 |
| 100 | ZAP70 | 0.31857531 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.37606652 |
| 2 | Parkinsons disease_Homo sapiens_hsa05012 | 3.79691389 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.41026715 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.11045453 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.01503306 |
| 6 | Asthma_Homo sapiens_hsa05310 | 2.97437386 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.71898495 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.65179427 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.58024606 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.42436385 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.39551566 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.27986800 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.25699418 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.14733231 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.09542486 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.95914279 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.93655331 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.89834703 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.87015310 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.73629063 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.67413386 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.60008186 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.47335799 |
| 24 | Homologous recombination_Homo sapiens_hsa03440 | 1.45468177 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.41736463 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.38715189 |
| 27 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.28076444 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.27320232 |
| 29 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.26938264 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.26177109 |
| 31 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.20499520 |
| 32 | Nicotine addiction_Homo sapiens_hsa05033 | 1.12922808 |
| 33 | Viral myocarditis_Homo sapiens_hsa05416 | 1.10086455 |
| 34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.09383430 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.04118320 |
| 36 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.03459450 |
| 37 | Leishmaniasis_Homo sapiens_hsa05140 | 0.99483905 |
| 38 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.98251740 |
| 39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.92479912 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89778295 |
| 41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.89685736 |
| 42 | Sulfur relay system_Homo sapiens_hsa04122 | 0.86235415 |
| 43 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.85033421 |
| 44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.84753272 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.83816210 |
| 46 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.81371129 |
| 47 | Base excision repair_Homo sapiens_hsa03410 | 0.78356218 |
| 48 | Mismatch repair_Homo sapiens_hsa03430 | 0.78330654 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.76198236 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.74781987 |
| 51 | Phagosome_Homo sapiens_hsa04145 | 0.73307339 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.70658378 |
| 53 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.69103112 |
| 54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.65643198 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60770950 |
| 56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.60641825 |
| 57 | Taste transduction_Homo sapiens_hsa04742 | 0.60259617 |
| 58 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.59964501 |
| 59 | GABAergic synapse_Homo sapiens_hsa04727 | 0.59254048 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.58754009 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.58152435 |
| 62 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.58100401 |
| 63 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.57081559 |
| 64 | Alcoholism_Homo sapiens_hsa05034 | 0.56470845 |
| 65 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.52985593 |
| 66 | Legionellosis_Homo sapiens_hsa05134 | 0.51962009 |
| 67 | Salmonella infection_Homo sapiens_hsa05132 | 0.48983845 |
| 68 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.48288305 |
| 69 | RNA transport_Homo sapiens_hsa03013 | 0.48234096 |
| 70 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47684192 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46926421 |
| 72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46205473 |
| 73 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.45588653 |
| 74 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.45487821 |
| 75 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45417174 |
| 76 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.44967000 |
| 77 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.44327750 |
| 78 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.43536436 |
| 79 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.40546914 |
| 80 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.39927071 |
| 81 | Tuberculosis_Homo sapiens_hsa05152 | 0.39872271 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39710177 |
| 83 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36154869 |
| 84 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.35334617 |
| 85 | DNA replication_Homo sapiens_hsa03030 | 0.33745708 |
| 86 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.33724102 |
| 87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33689131 |
| 88 | Morphine addiction_Homo sapiens_hsa05032 | 0.33597627 |
| 89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.32401051 |
| 90 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.31465458 |
| 91 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.31419785 |
| 92 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.30976779 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.30735622 |
| 94 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.29298121 |
| 95 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.28273501 |
| 96 | Shigellosis_Homo sapiens_hsa05131 | 0.26328864 |
| 97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.25802495 |
| 98 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.24860659 |
| 99 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.23181782 |
| 100 | Cocaine addiction_Homo sapiens_hsa05030 | 0.21763172 |

