RAD54B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.62933707
2DNA strand elongation involved in DNA replication (GO:0006271)5.19545932
3mitotic metaphase plate congression (GO:0007080)5.12325375
4DNA unwinding involved in DNA replication (GO:0006268)5.07746082
5telomere maintenance via semi-conservative replication (GO:0032201)5.06004875
6DNA replication initiation (GO:0006270)5.00889141
7mitotic chromosome condensation (GO:0007076)4.96082388
8DNA strand elongation (GO:0022616)4.94016205
9protein localization to chromosome, centromeric region (GO:0071459)4.87246690
10kinetochore organization (GO:0051383)4.84816993
11DNA replication checkpoint (GO:0000076)4.80965561
12chromatin remodeling at centromere (GO:0031055)4.75310936
13CENP-A containing nucleosome assembly (GO:0034080)4.74288276
14metaphase plate congression (GO:0051310)4.73144504
15telomere maintenance via recombination (GO:0000722)4.67511711
16* mitotic recombination (GO:0006312)4.63288748
17attachment of spindle microtubules to kinetochore (GO:0008608)4.50125962
18nuclear pore organization (GO:0006999)4.44159371
19mitotic sister chromatid segregation (GO:0000070)4.35675602
20establishment of integrated proviral latency (GO:0075713)4.34903965
21DNA replication-independent nucleosome organization (GO:0034724)4.34617775
22DNA replication-independent nucleosome assembly (GO:0006336)4.34617775
23DNA replication-dependent nucleosome assembly (GO:0006335)4.30558310
24DNA replication-dependent nucleosome organization (GO:0034723)4.30558310
25kinetochore assembly (GO:0051382)4.23869336
26meiotic chromosome segregation (GO:0045132)4.22763060
27establishment of chromosome localization (GO:0051303)4.21713125
28nuclear pore complex assembly (GO:0051292)4.19380477
29DNA double-strand break processing (GO:0000729)4.18394682
30sister chromatid segregation (GO:0000819)4.12509289
31nucleobase biosynthetic process (GO:0046112)4.11905789
32telomere maintenance via telomere lengthening (GO:0010833)4.11683707
33purine nucleobase biosynthetic process (GO:0009113)4.10985068
34mitotic nuclear envelope disassembly (GO:0007077)4.10515897
35nucleotide-excision repair, DNA gap filling (GO:0006297)4.08896859
36histone exchange (GO:0043486)4.01272622
37regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.98856985
38regulation of spindle organization (GO:0090224)3.97075266
39DNA ligation (GO:0006266)3.93957263
40regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.93805375
41replication fork processing (GO:0031297)3.80501755
42membrane disassembly (GO:0030397)3.78213329
43nuclear envelope disassembly (GO:0051081)3.78213329
44mitotic sister chromatid cohesion (GO:0007064)3.73831218
45regulation of double-strand break repair via homologous recombination (GO:0010569)3.68994398
46spindle checkpoint (GO:0031577)3.68994297
47positive regulation of chromosome segregation (GO:0051984)3.67397256
48non-recombinational repair (GO:0000726)3.67365502
49double-strand break repair via nonhomologous end joining (GO:0006303)3.67365502
50regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.66356517
51mismatch repair (GO:0006298)3.65071013
52IMP biosynthetic process (GO:0006188)3.62857705
53somatic diversification of immune receptors via somatic mutation (GO:0002566)3.62651405
54somatic hypermutation of immunoglobulin genes (GO:0016446)3.62651405
55protein localization to chromosome (GO:0034502)3.60836063
56regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.57512056
57regulation of mitotic spindle checkpoint (GO:1903504)3.57512056
58regulation of chromosome segregation (GO:0051983)3.54865182
59regulation of nuclear cell cycle DNA replication (GO:0033262)3.53982717
60regulation of mitotic spindle organization (GO:0060236)3.49559647
61negative regulation of chromosome segregation (GO:0051985)3.48534594
62regulation of centrosome cycle (GO:0046605)3.48348840
63regulation of mitotic metaphase/anaphase transition (GO:0030071)3.47381105
64* DNA geometric change (GO:0032392)3.47069911
65protein K6-linked ubiquitination (GO:0085020)3.46227976
66* DNA duplex unwinding (GO:0032508)3.45820629
67spindle assembly checkpoint (GO:0071173)3.44932627
68negative regulation of mitotic sister chromatid segregation (GO:0033048)3.44288789
69negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.44288789
70negative regulation of sister chromatid segregation (GO:0033046)3.44288789
71negative regulation of mitotic sister chromatid separation (GO:2000816)3.44288789
72chromatin assembly or disassembly (GO:0006333)3.44095285
73chromosome segregation (GO:0007059)3.40787045
74regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.40483773
75regulation of DNA endoreduplication (GO:0032875)3.38841364
76pore complex assembly (GO:0046931)3.38251973
77mitotic spindle checkpoint (GO:0071174)3.36452294
78negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.35453781
79DNA catabolic process, exonucleolytic (GO:0000738)3.35229910
80mitotic spindle assembly checkpoint (GO:0007094)3.33910913
81positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.33386580
82positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.33386580
83positive regulation of mitotic sister chromatid separation (GO:1901970)3.33386580
84DNA strand renaturation (GO:0000733)3.32802140
85mitotic G2/M transition checkpoint (GO:0044818)3.32788526
86DNA topological change (GO:0006265)3.32670530
87telomere maintenance (GO:0000723)3.32366229
88chromosome condensation (GO:0030261)3.31425253
89telomere organization (GO:0032200)3.30893710
90regulation of sister chromatid cohesion (GO:0007063)3.30576546
91regulation of sister chromatid segregation (GO:0033045)3.29780236
92regulation of mitotic sister chromatid separation (GO:0010965)3.29780236
93regulation of mitotic sister chromatid segregation (GO:0033047)3.29780236
94maturation of SSU-rRNA (GO:0030490)3.29169346
95maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.29095970
96folic acid-containing compound biosynthetic process (GO:0009396)3.28573652
97establishment of viral latency (GO:0019043)3.27176760
98regulation of centriole replication (GO:0046599)3.21305569
99* DNA conformation change (GO:0071103)3.20970244
100ribosome assembly (GO:0042255)3.19008893
101ATP-dependent chromatin remodeling (GO:0043044)3.18435261
102translesion synthesis (GO:0019985)3.18078897
103formation of translation preinitiation complex (GO:0001731)3.16202786
104DNA packaging (GO:0006323)3.14856879
105negative regulation of mitosis (GO:0045839)3.13768163
106regulation of centrosome duplication (GO:0010824)3.13647463
107anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.12465951
108proteasome assembly (GO:0043248)3.12442619
109IMP metabolic process (GO:0046040)3.12440911
110negative regulation of DNA-dependent DNA replication (GO:2000104)3.12152118
111ribosome biogenesis (GO:0042254)3.10600964
112negative regulation of DNA recombination (GO:0045910)3.10264203
113transcription-coupled nucleotide-excision repair (GO:0006283)3.08957597
114regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.06269489
115mitotic cell cycle (GO:0000278)3.05532030
116postreplication repair (GO:0006301)3.04947869
117regulation of histone H3-K9 methylation (GO:0051570)3.02751967
118negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.02168005
119response to X-ray (GO:0010165)3.01339987
120deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.01029692
121ribosomal small subunit assembly (GO:0000028)3.00655606

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.60086002
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.61158599
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.86608866
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.85112768
5* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.97508531
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.94881320
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.82813209
8AR_21909140_ChIP-Seq_LNCAP_Human2.73584889
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.67621094
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.63843365
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.51207096
12E2F1_21310950_ChIP-Seq_MCF-7_Human2.44427956
13MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.43715275
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.40266046
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.30817162
16* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.27866572
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.27045917
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.24914415
19GABP_17652178_ChIP-ChIP_JURKAT_Human2.23902463
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.18936735
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14203388
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12194155
23EGR1_19374776_ChIP-ChIP_THP-1_Human2.12142931
24XRN2_22483619_ChIP-Seq_HELA_Human2.09320230
25E2F7_22180533_ChIP-Seq_HELA_Human11.2102822
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.99437847
27VDR_23849224_ChIP-Seq_CD4+_Human1.95889030
28MYCN_18555785_ChIP-Seq_MESCs_Mouse1.88570958
29FOXP3_21729870_ChIP-Seq_TREG_Human1.81335544
30NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80311370
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.78751188
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78513816
33DCP1A_22483619_ChIP-Seq_HELA_Human1.73646466
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71244822
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65782176
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65325254
37TTF2_22483619_ChIP-Seq_HELA_Human1.61903585
38EWS_26573619_Chip-Seq_HEK293_Human1.55806795
39THAP11_20581084_ChIP-Seq_MESCs_Mouse1.54393614
40NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53606101
41ELK1_19687146_ChIP-ChIP_HELA_Human1.52502293
42GABP_19822575_ChIP-Seq_HepG2_Human1.52414275
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.50686129
44TP63_19390658_ChIP-ChIP_HaCaT_Human1.49412450
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.47289749
46HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.45878280
47CIITA_25753668_ChIP-Seq_RAJI_Human1.44483721
48* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.42846970
49* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.41559278
50* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.40304189
51KDM5A_27292631_Chip-Seq_BREAST_Human1.39202147
52SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.39054606
53FUS_26573619_Chip-Seq_HEK293_Human1.39054089
54POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.35570809
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.34884970
56PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.34212691
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33913015
58HOXB4_20404135_ChIP-ChIP_EML_Mouse1.33521617
59* NANOG_16153702_ChIP-ChIP_HESCs_Human1.32373282
60SOX2_18555785_ChIP-Seq_MESCs_Mouse1.30631222
61YY1_21170310_ChIP-Seq_MESCs_Mouse1.23838683
62* SOX2_16153702_ChIP-ChIP_HESCs_Human1.21098147
63E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20675900
64TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.20248271
65HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.20183641
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19655166
67STAT3_1855785_ChIP-Seq_MESCs_Mouse1.16976739
68RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15025240
69MYC_22102868_ChIP-Seq_BL_Human1.13753617
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.13186600
71SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.12666006
72KLF4_18555785_ChIP-Seq_MESCs_Mouse1.11660220
73ZNF274_21170338_ChIP-Seq_K562_Hela1.11061058
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10977236
75SRF_21415370_ChIP-Seq_HL-1_Mouse1.08475982
76CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07868165
77* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.05845744
78CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.03242802
79IRF1_19129219_ChIP-ChIP_H3396_Human1.02814472
80ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01347232
81TFEB_21752829_ChIP-Seq_HELA_Human1.01155247
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00692654
83* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00369354
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00264277
85HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.99799363
86MYC_18940864_ChIP-ChIP_HL60_Human0.99679759
87ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97962090
88FLI1_27457419_Chip-Seq_LIVER_Mouse0.97335670
89SOX17_20123909_ChIP-Seq_XEN_Mouse0.96041885
90VDR_22108803_ChIP-Seq_LS180_Human0.95738067
91CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.94581595
92NANOG_21062744_ChIP-ChIP_HESCs_Human0.92104488
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87834362
94TCF3_18692474_ChIP-Seq_MEFs_Mouse0.87423871
95KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87178596
96IGF1R_20145208_ChIP-Seq_DFB_Human0.85496063
97KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.85126468
98KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.85126468
99KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.85126468
100SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.83374694
101NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.82795630
102FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.82155586
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.82130882
104CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82028298
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.81351046
106NOTCH1_21737748_ChIP-Seq_TLL_Human0.79661272
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78917467
108NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.76712077
109SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.76674071
110NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.76047981
111TAF15_26573619_Chip-Seq_HEK293_Human0.75771929
112RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.74463131
113GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.74042589
114HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.74026526
115CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.73962214
116BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.73274052
117TCF3_18692474_ChIP-Seq_MESCs_Mouse0.72710181
118* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.72666906
119* P300_19829295_ChIP-Seq_ESCs_Human0.72665145
120SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.72359751
121PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.72354116
122ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.68071423
123CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.66080067
124PCGF2_27294783_Chip-Seq_ESCs_Mouse0.64708411
125SOX9_26525672_Chip-Seq_HEART_Mouse0.62242260
126GATA1_26923725_Chip-Seq_HPCs_Mouse0.61864650

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.67634493
2MP0010094_abnormal_chromosome_stability5.32656970
3MP0008057_abnormal_DNA_replication4.92868737
4MP0003111_abnormal_nucleus_morphology4.90008343
5MP0004957_abnormal_blastocyst_morpholog4.46525424
6MP0003077_abnormal_cell_cycle4.23811409
7MP0008058_abnormal_DNA_repair3.66948116
8MP0008007_abnormal_cellular_replicative2.89504878
9MP0008932_abnormal_embryonic_tissue2.81680448
10MP0008877_abnormal_DNA_methylation2.67699969
11MP0010352_gastrointestinal_tract_polyps2.32912012
12MP0003123_paternal_imprinting2.31610547
13MP0001730_embryonic_growth_arrest2.25593237
14MP0002396_abnormal_hematopoietic_system2.24524171
15MP0000350_abnormal_cell_proliferation2.20066891
16MP0003786_premature_aging2.18776720
17MP0010307_abnormal_tumor_latency1.99567642
18MP0002938_white_spotting1.83095602
19MP0005380_embryogenesis_phenotype1.82322162
20MP0001672_abnormal_embryogenesis/_devel1.82322162
21MP0001697_abnormal_embryo_size1.70343150
22MP0003984_embryonic_growth_retardation1.57718529
23MP0002085_abnormal_embryonic_tissue1.56453202
24MP0003567_abnormal_fetal_cardiomyocyte1.56037965
25MP0002088_abnormal_embryonic_growth/wei1.54125981
26MP0003718_maternal_effect1.54055651
27MP0000490_abnormal_crypts_of1.53812604
28MP0003121_genomic_imprinting1.51994221
29MP0002080_prenatal_lethality1.51894044
30MP0004808_abnormal_hematopoietic_stem1.49574216
31MP0003890_abnormal_embryonic-extraembry1.49218333
32MP0002084_abnormal_developmental_patter1.48095792
33MP0003136_yellow_coat_color1.46759127
34MP0002210_abnormal_sex_determination1.46695819
35MP0002086_abnormal_extraembryonic_tissu1.44297014
36* MP0000313_abnormal_cell_death1.39242222
37MP0008789_abnormal_olfactory_epithelium1.38577685
38MP0002697_abnormal_eye_size1.35155341
39MP0002019_abnormal_tumor_incidence1.33179481
40MP0006072_abnormal_retinal_apoptosis1.31816599
41MP0003315_abnormal_perineum_morphology1.29640110
42MP0004197_abnormal_fetal_growth/weight/1.28162510
43MP0001145_abnormal_male_reproductive1.27331951
44MP0002233_abnormal_nose_morphology1.22489995
45MP0005397_hematopoietic_system_phenotyp1.22192607
46MP0001545_abnormal_hematopoietic_system1.22192607
47MP0006035_abnormal_mitochondrial_morpho1.21585144
48MP0002102_abnormal_ear_morphology1.20901818
49MP0009053_abnormal_anal_canal1.17418093
50MP0001929_abnormal_gametogenesis1.16892287
51MP0005394_taste/olfaction_phenotype1.11536992
52MP0005499_abnormal_olfactory_system1.11536992
53MP0005076_abnormal_cell_differentiation1.11423183
54MP0003941_abnormal_skin_development1.10447894
55MP0001293_anophthalmia1.09426092
56MP0000653_abnormal_sex_gland1.09392887
57MP0000579_abnormal_nail_morphology1.07760749
58MP0003937_abnormal_limbs/digits/tail_de1.03869290
59MP0001529_abnormal_vocalization1.02531377
60MP0001346_abnormal_lacrimal_gland1.02291303
61MP0003806_abnormal_nucleotide_metabolis1.01073460
62MP0002751_abnormal_autonomic_nervous1.00744435
63MP0001119_abnormal_female_reproductive0.97282370
64MP0000372_irregular_coat_pigmentation0.97128461
65MP0001177_atelectasis0.96250765
66MP0002234_abnormal_pharynx_morphology0.94274973
67MP0010030_abnormal_orbit_morphology0.94031087
68MP0003119_abnormal_digestive_system0.92908294
69MP0000647_abnormal_sebaceous_gland0.89029092
70MP0006292_abnormal_olfactory_placode0.89029011
71MP0000703_abnormal_thymus_morphology0.88426379
72MP0005408_hypopigmentation0.88207370
73MP0009278_abnormal_bone_marrow0.86799717
74MP0003861_abnormal_nervous_system0.85715101
75MP0009333_abnormal_splenocyte_physiolog0.85082607
76MP0005395_other_phenotype0.83497939
77MP0009672_abnormal_birth_weight0.82804893
78MP0000427_abnormal_hair_cycle0.81460191
79MP0004147_increased_porphyrin_level0.81148887
80MP0009697_abnormal_copulation0.81141416
81MP0002111_abnormal_tail_morphology0.80219905
82MP0005391_vision/eye_phenotype0.79457479
83MP0000566_synostosis0.79373436
84MP0004264_abnormal_extraembryonic_tissu0.76832272
85MP0000383_abnormal_hair_follicle0.76215339
86MP0001286_abnormal_eye_development0.75893370
87MP0009703_decreased_birth_body0.75514010
88MP0002722_abnormal_immune_system0.73846738
89MP0002398_abnormal_bone_marrow0.73750518
90MP0000537_abnormal_urethra_morphology0.73454107
91MP0004133_heterotaxia0.73002426
92MP0002160_abnormal_reproductive_system0.71842160
93MP0005171_absent_coat_pigmentation0.70766323
94MP0008995_early_reproductive_senescence0.70215938
95MP0000689_abnormal_spleen_morphology0.69688377
96MP0005389_reproductive_system_phenotype0.69633821
97MP0001299_abnormal_eye_distance/0.69048162
98MP0000049_abnormal_middle_ear0.67429552
99* MP0005384_cellular_phenotype0.67256429
100MP0003787_abnormal_imprinting0.66840276
101MP0001661_extended_life_span0.65716990
102MP0003943_abnormal_hepatobiliary_system0.65217698
103MP0005253_abnormal_eye_physiology0.65050826
104MP0003186_abnormal_redox_activity0.64067695
105MP0002092_abnormal_eye_morphology0.63979318
106MP0005023_abnormal_wound_healing0.62569939
107MP0002075_abnormal_coat/hair_pigmentati0.62515319
108MP0000631_abnormal_neuroendocrine_gland0.62411316
109* MP0005621_abnormal_cell_physiology0.62192711
110MP0003699_abnormal_female_reproductive0.61259826
111MP0006054_spinal_hemorrhage0.61118904
112MP0001915_intracranial_hemorrhage0.60657302
113MP0000432_abnormal_head_morphology0.60650771
114MP0003938_abnormal_ear_development0.60138270
115MP0010678_abnormal_skin_adnexa0.59811345
116MP0003698_abnormal_male_reproductive0.59786900
117MP0002132_abnormal_respiratory_system0.59617947
118MP0003763_abnormal_thymus_physiology0.59371042
119MP0000477_abnormal_intestine_morphology0.58972392
120MP0002095_abnormal_skin_pigmentation0.58930780
121MP0001849_ear_inflammation0.57689298
122* MP0002429_abnormal_blood_cell0.55170792
123MP0005075_abnormal_melanosome_morpholog0.54814884
124MP0000358_abnormal_cell_content/0.54687192
125MP0001186_pigmentation_phenotype0.54649157
126MP0003221_abnormal_cardiomyocyte_apopto0.54318877
127MP0003935_abnormal_craniofacial_develop0.54154627
128MP0002161_abnormal_fertility/fecundity0.53264015
129MP0000858_altered_metastatic_potential0.52956392
130MP0001727_abnormal_embryo_implantation0.52514736
131MP0003936_abnormal_reproductive_system0.52199700
132MP0000428_abnormal_craniofacial_morphol0.51872546
133MP0000015_abnormal_ear_pigmentation0.51851589
134MP0002009_preneoplasia0.51349930
135MP0003755_abnormal_palate_morphology0.51136957
136MP0001919_abnormal_reproductive_system0.51074155

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.58070103
2Chromosomal breakage induced by crosslinking agents (HP:0003221)5.22479247
3Birth length less than 3rd percentile (HP:0003561)4.85111081
4Abnormality of chromosome stability (HP:0003220)4.30617530
5Meckel diverticulum (HP:0002245)3.97746765
6Abnormality of the preputium (HP:0100587)3.85991934
7Abnormality of the ileum (HP:0001549)3.79787696
8Breast hypoplasia (HP:0003187)3.77840300
9Reticulocytopenia (HP:0001896)3.75143048
10Colon cancer (HP:0003003)3.68945217
11Aplasia/Hypoplasia of the uvula (HP:0010293)3.66121872
12Medulloblastoma (HP:0002885)3.50650179
13Impulsivity (HP:0100710)3.45965121
14Patellar aplasia (HP:0006443)3.43503248
15Ependymoma (HP:0002888)3.31702879
16Small intestinal stenosis (HP:0012848)3.30912921
17Duodenal stenosis (HP:0100867)3.30912921
18Selective tooth agenesis (HP:0001592)3.22037300
19Aplasia/Hypoplasia of the patella (HP:0006498)3.17603709
20Absent radius (HP:0003974)3.13630296
21Ectopic kidney (HP:0000086)3.08624997
22Abnormality of the labia minora (HP:0012880)3.00455477
23Myelodysplasia (HP:0002863)2.98841997
24Agnosia (HP:0010524)2.95045871
25Oral leukoplakia (HP:0002745)2.93255555
26Abnormal lung lobation (HP:0002101)2.92945462
27Absent forearm bone (HP:0003953)2.90824017
28Aplasia involving forearm bones (HP:0009822)2.90824017
29Carpal bone hypoplasia (HP:0001498)2.90535519
3011 pairs of ribs (HP:0000878)2.90104930
31Absent thumb (HP:0009777)2.89304812
32Sloping forehead (HP:0000340)2.83314906
33Nephroblastoma (Wilms tumor) (HP:0002667)2.78466821
34Bone marrow hypocellularity (HP:0005528)2.75637387
35Rhabdomyosarcoma (HP:0002859)2.75031119
36Abnormality of the duodenum (HP:0002246)2.71687724
37Volvulus (HP:0002580)2.71083271
38Abnormality of the carotid arteries (HP:0005344)2.68040571
39Duplicated collecting system (HP:0000081)2.60636198
40Supernumerary spleens (HP:0009799)2.60607536
41Cortical dysplasia (HP:0002539)2.60557786
42Embryonal renal neoplasm (HP:0011794)2.57057529
43Increased nuchal translucency (HP:0010880)2.55006072
44Clubbing of toes (HP:0100760)2.50880796
45Aplastic anemia (HP:0001915)2.45011746
46Degeneration of anterior horn cells (HP:0002398)2.42803454
47Abnormality of the anterior horn cell (HP:0006802)2.42803454
48Facial hemangioma (HP:0000329)2.40824827
49Short thumb (HP:0009778)2.40709852
50Rough bone trabeculation (HP:0100670)2.39726417
51Neoplasm of the pancreas (HP:0002894)2.39489729
52Tracheoesophageal fistula (HP:0002575)2.35858198
53Premature graying of hair (HP:0002216)2.33426418
54Abnormality of cells of the erythroid lineage (HP:0012130)2.31745211
55Abnormality of the renal collecting system (HP:0004742)2.31478829
56Cafe-au-lait spot (HP:0000957)2.28352134
57Oligodactyly (hands) (HP:0001180)2.27792807
58Triphalangeal thumb (HP:0001199)2.27705688
59Abnormal number of erythroid precursors (HP:0012131)2.26303944
60Proximal placement of thumb (HP:0009623)2.23495748
61Horseshoe kidney (HP:0000085)2.20830687
62Abnormality of the astrocytes (HP:0100707)2.20120423
63Astrocytoma (HP:0009592)2.20120423
64Glioma (HP:0009733)2.19710743
65Deviation of the thumb (HP:0009603)2.16320056
66Abnormal number of incisors (HP:0011064)2.16011061
67Missing ribs (HP:0000921)2.14120662
68Aplasia/Hypoplasia of the sternum (HP:0006714)2.11968285
69Microretrognathia (HP:0000308)2.06421156
70Atresia of the external auditory canal (HP:0000413)2.06250242
71Neoplasm of the oral cavity (HP:0100649)2.02169478
72Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.02157984
73Basal cell carcinoma (HP:0002671)2.01564878
74Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.00928891
75Short 4th metacarpal (HP:0010044)2.00928891
76Amaurosis fugax (HP:0100576)1.99920717
77Neoplasm of the colon (HP:0100273)1.97958344
78Squamous cell carcinoma (HP:0002860)1.97409883
79Prominent nose (HP:0000448)1.96876380
80Biliary tract neoplasm (HP:0100574)1.96608302
81High pitched voice (HP:0001620)1.96077168
82Septo-optic dysplasia (HP:0100842)1.95578224
83Abnormality of DNA repair (HP:0003254)1.95045303
84Increased serum pyruvate (HP:0003542)1.94493090
85Abnormality of glycolysis (HP:0004366)1.93978021
86Cellular immunodeficiency (HP:0005374)1.93093335
87Abnormality of pyrimidine metabolism (HP:0004353)1.92346771
88Abnormality of methionine metabolism (HP:0010901)1.88982802
89Neoplasm of striated muscle (HP:0009728)1.88911005
90Aplasia/Hypoplasia of the sacrum (HP:0008517)1.88632906
91Facial cleft (HP:0002006)1.87758493
92Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.86826834
93Abnormality of alanine metabolism (HP:0010916)1.86826834
94Hyperalaninemia (HP:0003348)1.86826834
95Aplasia/Hypoplasia of the earlobes (HP:0009906)1.85166994
96Pallor (HP:0000980)1.85146749
97Aplasia/hypoplasia of the humerus (HP:0006507)1.84734184
98Abnormal spermatogenesis (HP:0008669)1.83906758
99Embryonal neoplasm (HP:0002898)1.82548808
100Multiple enchondromatosis (HP:0005701)1.80120003
101Abnormal umbilical cord blood vessels (HP:0011403)1.79006175
102Single umbilical artery (HP:0001195)1.79006175
103Abnormality of the fetal cardiovascular system (HP:0010948)1.79006175
104Hypoplasia of the capital femoral epiphysis (HP:0003090)1.78654636
105Macrocytic anemia (HP:0001972)1.77114541
106Choanal atresia (HP:0000453)1.76902198
107Shawl scrotum (HP:0000049)1.75248849
108Cleft eyelid (HP:0000625)1.75230273
109Hypoplastic pelvis (HP:0008839)1.75143302
110Abnormality of serum amino acid levels (HP:0003112)1.74790663
111Ovarian neoplasm (HP:0100615)1.74547208
112Spinal muscular atrophy (HP:0007269)1.73481712
113Abnormality of the septum pellucidum (HP:0007375)1.73129982
114Preaxial hand polydactyly (HP:0001177)1.72044195
115Abnormality of chromosome segregation (HP:0002916)1.71518810
116Abnormal trabecular bone morphology (HP:0100671)1.71090545
117Arteriovenous malformation (HP:0100026)1.70750680
118Astigmatism (HP:0000483)1.69247485
119Gonadotropin excess (HP:0000837)1.68895904
120Stenosis of the external auditory canal (HP:0000402)1.68263592
121Deep philtrum (HP:0002002)1.68077524
122Oligodactyly (HP:0012165)1.68071513
123Absent septum pellucidum (HP:0001331)1.68056442
124Intestinal atresia (HP:0011100)1.64349114
125Duplication of thumb phalanx (HP:0009942)1.63972538
126Abnormality of cochlea (HP:0000375)1.62802679
127Esophageal atresia (HP:0002032)1.60283813
128Microvesicular hepatic steatosis (HP:0001414)1.59164320
129Dandy-Walker malformation (HP:0001305)1.59047274
130Neoplasm of the small intestine (HP:0100833)1.58702597
131Neoplasm of the adrenal gland (HP:0100631)1.58457639
132Increased hepatocellular lipid droplets (HP:0006565)1.56368538
133Oligohydramnios (HP:0001562)1.55510143
134Abnormality of aspartate family amino acid metabolism (HP:0010899)1.55024365
135Small hand (HP:0200055)1.53915761
136Pancreatic islet-cell hyperplasia (HP:0004510)1.53476185
137Bilateral microphthalmos (HP:0007633)1.53433982
138Bifid tongue (HP:0010297)1.52495739
139Megaloblastic anemia (HP:0001889)1.52451324
140Acute encephalopathy (HP:0006846)1.51776121

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE15.16731715
2CDC75.06652993
3BUB14.21082643
4NEK23.11472807
5TTK3.10717659
6SRPK12.82411490
7EIF2AK12.49841589
8BRSK22.44788170
9PLK12.38821918
10NEK12.37167715
11PLK42.36743967
12ACVR1B2.25898622
13VRK22.08630290
14AURKB2.00609325
15ATR1.97714624
16PLK31.97544145
17CCNB11.94260644
18TSSK61.93149005
19CDK121.91163709
20MKNK11.88486260
21BMPR1B1.84959579
22VRK11.83864381
23CHEK21.77700923
24CDK71.75503551
25PASK1.70459369
26TRIM281.70420378
27TAF11.57742387
28BRSK11.56757519
29TLK11.52736243
30STK161.46976768
31CDK41.44095262
32MKNK21.43948707
33DYRK31.43774125
34ZAK1.43463579
35EIF2AK31.43332097
36TNIK1.42183747
37NUAK11.42183151
38CHEK11.41463868
39MAP3K81.41199003
40STK41.39856481
41BRD41.28762668
42EPHA21.24759330
43STK101.23115807
44AURKA1.21797299
45RPS6KB21.18567813
46ATM1.15008564
47WNK31.12058926
48ERBB41.11348388
49ERBB31.08979637
50EIF2AK21.07515925
51MELK1.07366229
52NME21.03830496
53CDK20.99302223
54RPS6KA40.97853498
55PLK20.97461381
56CLK10.96556477
57LATS10.94312206
58CDK60.93280531
59PNCK0.89499609
60TESK20.88936718
61CDK80.88135402
62PIM10.87461538
63NME10.87144293
64CDK10.85365439
65TGFBR10.83630766
66INSRR0.81162817
67PBK0.76870134
68STK30.76243963
69ALK0.74609326
70MET0.73250619
71PAK40.72555133
72SCYL20.70660422
73BCR0.67270168
74CSNK2A10.64930921
75STK390.64117387
76CSNK2A20.60515242
77BRAF0.60285109
78MAP4K20.59410121
79STK38L0.58240887
80PRKCI0.55794500
81FGFR10.55340639
82CSNK1G10.52557213
83DYRK20.47099658
84PRKDC0.46346433
85YES10.45152210
86MST1R0.43869208
87TEC0.43536094
88PAK10.43390720
89TAOK20.42370854
90RPS6KA50.41414055
91MAP3K100.41288489
92EEF2K0.41041562
93NEK60.40645139
94MAP3K40.40090337
95MAPK140.37548200
96IRAK30.37501538
97CDK30.33586188
98MTOR0.33005806
99AKT20.32802494
100FLT30.32646395
101OXSR10.32013973
102CSNK1D0.31277091
103CSNK1A1L0.30814676
104CSNK1G30.30715290
105CSNK1E0.30403157
106SMG10.29607449
107AKT30.28901770
108CSNK1G20.27353069
109CDK180.27053702
110GSK3B0.26451256
111AKT10.26239038
112MARK30.24803664
113CDK90.23885954
114PIM20.23599538
115CDK150.22095382
116MAPK10.21062703
117MST40.20556502
118CDK11A0.20470083
119CDK140.19891719
120CHUK0.19215642
121LATS20.18709354
122PDK20.18293066
123MAP3K50.18280971
124NEK90.17551773
125RPS6KC10.17439525
126RPS6KL10.17439525
127RPS6KA60.16671106
128CSF1R0.16297888
129LRRK20.15969798
130RPS6KB10.15405578
131MAP4K10.14919576
132IRAK40.14124269
133MAPK110.14003610
134MAP2K30.13365245

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.57985553
2Mismatch repair_Homo sapiens_hsa034304.93240606
3* Homologous recombination_Homo sapiens_hsa034403.60209875
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.56555030
5Base excision repair_Homo sapiens_hsa034103.53988567
6Spliceosome_Homo sapiens_hsa030403.21324118
7Cell cycle_Homo sapiens_hsa041103.20609027
8Nucleotide excision repair_Homo sapiens_hsa034203.15224140
9Fanconi anemia pathway_Homo sapiens_hsa034603.08183780
10RNA transport_Homo sapiens_hsa030133.04079454
11RNA polymerase_Homo sapiens_hsa030202.89558510
12One carbon pool by folate_Homo sapiens_hsa006702.78508506
13Non-homologous end-joining_Homo sapiens_hsa034502.51102795
14Pyrimidine metabolism_Homo sapiens_hsa002402.45261327
15Ribosome_Homo sapiens_hsa030102.42843167
16Proteasome_Homo sapiens_hsa030502.38542397
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.16790538
18Basal transcription factors_Homo sapiens_hsa030222.05472787
19RNA degradation_Homo sapiens_hsa030181.96906604
20mRNA surveillance pathway_Homo sapiens_hsa030151.85857888
21p53 signaling pathway_Homo sapiens_hsa041151.77536915
22Propanoate metabolism_Homo sapiens_hsa006401.59132124
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.51984214
24Pyruvate metabolism_Homo sapiens_hsa006201.42320133
25Systemic lupus erythematosus_Homo sapiens_hsa053221.35295917
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.34236407
27Purine metabolism_Homo sapiens_hsa002301.34052310
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.28626167
29Steroid biosynthesis_Homo sapiens_hsa001001.25346643
30Vitamin B6 metabolism_Homo sapiens_hsa007501.24496687
31Oocyte meiosis_Homo sapiens_hsa041141.15872769
32Epstein-Barr virus infection_Homo sapiens_hsa051691.10306296
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.03397648
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.02570442
35Viral carcinogenesis_Homo sapiens_hsa052030.98328570
36Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.97995017
37Herpes simplex infection_Homo sapiens_hsa051680.95213844
38Parkinsons disease_Homo sapiens_hsa050120.85421376
39Drug metabolism - other enzymes_Homo sapiens_hsa009830.84571772
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84402573
41Fatty acid elongation_Homo sapiens_hsa000620.83557378
42Oxidative phosphorylation_Homo sapiens_hsa001900.78536224
43HTLV-I infection_Homo sapiens_hsa051660.78232275
44Antigen processing and presentation_Homo sapiens_hsa046120.75735846
45Selenocompound metabolism_Homo sapiens_hsa004500.74160114
46MicroRNAs in cancer_Homo sapiens_hsa052060.71953110
47Pentose phosphate pathway_Homo sapiens_hsa000300.68959311
48Folate biosynthesis_Homo sapiens_hsa007900.67494609
49Cysteine and methionine metabolism_Homo sapiens_hsa002700.65667211
50Small cell lung cancer_Homo sapiens_hsa052220.64287448
51Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63878772
52Biosynthesis of amino acids_Homo sapiens_hsa012300.60291611
53Cyanoamino acid metabolism_Homo sapiens_hsa004600.56144349
54Transcriptional misregulation in cancer_Homo sapiens_hsa052020.55718100
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50720765
56Thyroid cancer_Homo sapiens_hsa052160.49299209
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49274424
58Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48128478
59TGF-beta signaling pathway_Homo sapiens_hsa043500.46859368
60Fatty acid metabolism_Homo sapiens_hsa012120.45395489
61Butanoate metabolism_Homo sapiens_hsa006500.44953114
62Alcoholism_Homo sapiens_hsa050340.44678481
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44599412
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.43210224
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40479515
66Hippo signaling pathway_Homo sapiens_hsa043900.40316257
67Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40273679
68Glutathione metabolism_Homo sapiens_hsa004800.38135678
69Basal cell carcinoma_Homo sapiens_hsa052170.37686810
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.36159872
71Legionellosis_Homo sapiens_hsa051340.35406857
72Colorectal cancer_Homo sapiens_hsa052100.34938508
73Lysine degradation_Homo sapiens_hsa003100.34463817
74Alzheimers disease_Homo sapiens_hsa050100.33820645
75Fatty acid degradation_Homo sapiens_hsa000710.33525118
76Apoptosis_Homo sapiens_hsa042100.33498210
77Pentose and glucuronate interconversions_Homo sapiens_hsa000400.33473590
78Primary immunodeficiency_Homo sapiens_hsa053400.31162183
79N-Glycan biosynthesis_Homo sapiens_hsa005100.30904458
80Adherens junction_Homo sapiens_hsa045200.30325272
81Arginine and proline metabolism_Homo sapiens_hsa003300.30232477
82NF-kappa B signaling pathway_Homo sapiens_hsa040640.29345208
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.27174999
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.26416570
85Hepatitis B_Homo sapiens_hsa051610.26174651
86Prostate cancer_Homo sapiens_hsa052150.25812265
87Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.25687272
88Pathways in cancer_Homo sapiens_hsa052000.25395531
89Phototransduction_Homo sapiens_hsa047440.24964059
90Peroxisome_Homo sapiens_hsa041460.24839047
91Notch signaling pathway_Homo sapiens_hsa043300.24691981
92Measles_Homo sapiens_hsa051620.23532649
93Bladder cancer_Homo sapiens_hsa052190.22386296
94Hematopoietic cell lineage_Homo sapiens_hsa046400.21749789
95Carbon metabolism_Homo sapiens_hsa012000.21261393
96Fructose and mannose metabolism_Homo sapiens_hsa000510.20951381
97Protein export_Homo sapiens_hsa030600.20086413
98Chronic myeloid leukemia_Homo sapiens_hsa052200.20071522
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.18972026
100Huntingtons disease_Homo sapiens_hsa050160.18791507
101Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.18588921
102Influenza A_Homo sapiens_hsa051640.17942220
103beta-Alanine metabolism_Homo sapiens_hsa004100.17603016
104NOD-like receptor signaling pathway_Homo sapiens_hsa046210.17440221
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.17237973
106HIF-1 signaling pathway_Homo sapiens_hsa040660.16702553
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.16213001
108Intestinal immune network for IgA production_Homo sapiens_hsa046720.15945849
109Sulfur relay system_Homo sapiens_hsa041220.15594082
110FoxO signaling pathway_Homo sapiens_hsa040680.14240469
111Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.13964122
112Hedgehog signaling pathway_Homo sapiens_hsa043400.12910334
113Metabolic pathways_Homo sapiens_hsa011000.12580021
114Renin-angiotensin system_Homo sapiens_hsa046140.12306384
115Nitrogen metabolism_Homo sapiens_hsa009100.12225621
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.11769623
117Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.09875101
118Melanoma_Homo sapiens_hsa052180.08936419
119Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.08879161
120Retinol metabolism_Homo sapiens_hsa008300.08862150
121Vitamin digestion and absorption_Homo sapiens_hsa049770.08729120
122Shigellosis_Homo sapiens_hsa051310.08097439
123Pancreatic cancer_Homo sapiens_hsa052120.07638186
124Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.07313983
125Arachidonic acid metabolism_Homo sapiens_hsa005900.06699334
126PI3K-Akt signaling pathway_Homo sapiens_hsa041510.06194244
127Wnt signaling pathway_Homo sapiens_hsa043100.06127725
128Viral myocarditis_Homo sapiens_hsa054160.04743491
129Non-small cell lung cancer_Homo sapiens_hsa052230.04146417
130Tight junction_Homo sapiens_hsa045300.01735248
1312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.01696435

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