RAD9B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)5.02934424
2behavioral response to nicotine (GO:0035095)4.79182256
3mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.61859922
4respiratory chain complex IV assembly (GO:0008535)4.31957868
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.17044401
6axoneme assembly (GO:0035082)4.11868858
7regulation of DNA endoreduplication (GO:0032875)4.09191073
8cytochrome complex assembly (GO:0017004)4.06730003
9indolalkylamine metabolic process (GO:0006586)4.04308953
10tryptophan catabolic process (GO:0006569)4.00042798
11indole-containing compound catabolic process (GO:0042436)4.00042798
12indolalkylamine catabolic process (GO:0046218)4.00042798
13presynaptic membrane assembly (GO:0097105)3.92677985
14synapsis (GO:0007129)3.82878212
15male meiosis I (GO:0007141)3.78372971
16detection of light stimulus involved in visual perception (GO:0050908)3.76866227
17detection of light stimulus involved in sensory perception (GO:0050962)3.76866227
18negative regulation of DNA-dependent DNA replication (GO:2000104)3.72923006
19intraciliary transport (GO:0042073)3.67315940
20detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.67061727
21protein complex biogenesis (GO:0070271)3.66117454
22tryptophan metabolic process (GO:0006568)3.62526012
23protein polyglutamylation (GO:0018095)3.60690506
24regulation of cilium movement (GO:0003352)3.59477291
25regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.56043087
26kynurenine metabolic process (GO:0070189)3.54119188
27respiratory electron transport chain (GO:0022904)3.52020015
28GTP biosynthetic process (GO:0006183)3.51969072
29ribosomal small subunit assembly (GO:0000028)3.49542026
30cytidine deamination (GO:0009972)3.47705574
31cytidine metabolic process (GO:0046087)3.47705574
32cytidine catabolic process (GO:0006216)3.47705574
33platelet dense granule organization (GO:0060155)3.45763172
34electron transport chain (GO:0022900)3.45580822
35DNA ligation (GO:0006266)3.36007694
36postsynaptic membrane organization (GO:0001941)3.34322046
37positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.31202337
38male meiosis (GO:0007140)3.30663360
39ribosomal small subunit biogenesis (GO:0042274)3.28713053
40response to pheromone (GO:0019236)3.26678869
41protein localization to cilium (GO:0061512)3.22550219
42mitochondrial respiratory chain complex assembly (GO:0033108)3.20969349
43photoreceptor cell maintenance (GO:0045494)3.19269741
44cellular response to ATP (GO:0071318)3.18051219
45presynaptic membrane organization (GO:0097090)3.16317436
46positive regulation of response to oxidative stress (GO:1902884)3.14905768
47positive regulation of cellular response to oxidative stress (GO:1900409)3.14905768
48inner mitochondrial membrane organization (GO:0007007)3.12714816
49protein deneddylation (GO:0000338)3.12445778
50viral transcription (GO:0019083)3.09660027
51centriole replication (GO:0007099)3.08571383
52regulation of rhodopsin mediated signaling pathway (GO:0022400)3.07847150
53negative regulation of mast cell activation (GO:0033004)3.07806115
54nonmotile primary cilium assembly (GO:0035058)3.07746949
55centriole assembly (GO:0098534)3.07186615
56positive regulation of prostaglandin secretion (GO:0032308)3.02055790
57meiosis I (GO:0007127)3.00245667
58neuronal action potential (GO:0019228)2.99434963
59sympathetic nervous system development (GO:0048485)2.97347121
60ribosomal large subunit biogenesis (GO:0042273)2.97206307
61DNA methylation involved in gamete generation (GO:0043046)2.96219392
62mitochondrial respiratory chain complex I assembly (GO:0032981)2.95584333
63NADH dehydrogenase complex assembly (GO:0010257)2.95584333
64mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.95584333
65sulfation (GO:0051923)2.95420784
66mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.94937727
67translational termination (GO:0006415)2.94583964
68lymphoid progenitor cell differentiation (GO:0002320)2.93898031
69reciprocal DNA recombination (GO:0035825)2.93752204
70reciprocal meiotic recombination (GO:0007131)2.93752204
71protein import into peroxisome matrix (GO:0016558)2.92849191
72cullin deneddylation (GO:0010388)2.89747781
73keratinocyte development (GO:0003334)2.89634551
74cellular ketone body metabolic process (GO:0046950)2.89072861
75protein heterotetramerization (GO:0051290)2.88902722
76negative regulation of alpha-beta T cell differentiation (GO:0046639)2.88399882
77rhodopsin mediated signaling pathway (GO:0016056)2.88005914
78tRNA methylation (GO:0030488)2.86815239
79termination of RNA polymerase III transcription (GO:0006386)2.85680987
80transcription elongation from RNA polymerase III promoter (GO:0006385)2.85680987
81energy coupled proton transport, down electrochemical gradient (GO:0015985)2.85049211
82ATP synthesis coupled proton transport (GO:0015986)2.85049211
83amine catabolic process (GO:0009310)2.84952225
84cellular biogenic amine catabolic process (GO:0042402)2.84952225
85axonemal dynein complex assembly (GO:0070286)2.84873509
86pyrimidine ribonucleoside catabolic process (GO:0046133)2.84672113
87positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)2.84341261
88proteasome assembly (GO:0043248)2.80990202
89negative regulation of telomere maintenance (GO:0032205)2.80364330
90chaperone-mediated protein transport (GO:0072321)2.79463429
91regulation of nuclear cell cycle DNA replication (GO:0033262)2.78309714
92retinal cone cell development (GO:0046549)2.78266174
93regulation of meiosis I (GO:0060631)2.78010987
94polyketide metabolic process (GO:0030638)2.76789399
95doxorubicin metabolic process (GO:0044598)2.76789399
96daunorubicin metabolic process (GO:0044597)2.76789399
97negative regulation of transcription by competitive promoter binding (GO:0010944)2.76124823
98behavioral response to ethanol (GO:0048149)2.75852389
99indole-containing compound metabolic process (GO:0042430)2.74292878
100photoreceptor cell development (GO:0042461)2.73991505
101glycerophospholipid catabolic process (GO:0046475)2.73896580
1027-methylguanosine RNA capping (GO:0009452)2.72466136
103RNA capping (GO:0036260)2.72466136
104DNA demethylation (GO:0080111)2.70910436
105cotranslational protein targeting to membrane (GO:0006613)2.70336119
106UTP biosynthetic process (GO:0006228)2.70326989
107ribonucleoprotein complex disassembly (GO:0032988)2.68800358
108ether lipid metabolic process (GO:0046485)2.68496991
109SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.68323364
1107-methylguanosine mRNA capping (GO:0006370)2.68191958
111mannosylation (GO:0097502)2.67721644
112L-fucose catabolic process (GO:0042355)2.67586662
113fucose catabolic process (GO:0019317)2.67586662
114L-fucose metabolic process (GO:0042354)2.67586662
115protein neddylation (GO:0045116)2.67270941
116preassembly of GPI anchor in ER membrane (GO:0016254)2.66283018
117ketone body metabolic process (GO:1902224)2.65915393
118regulation of memory T cell differentiation (GO:0043380)2.65888211
119regulation of mitochondrial translation (GO:0070129)2.65844754
120G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.65568362
121auditory receptor cell stereocilium organization (GO:0060088)2.65473556
122protein targeting to ER (GO:0045047)2.65304638
123positive regulation of fatty acid transport (GO:2000193)2.64911097
124ovulation cycle (GO:0042698)2.64087434
125negative regulation of execution phase of apoptosis (GO:1900118)2.63022173
126organelle disassembly (GO:1903008)2.62574951
127definitive hemopoiesis (GO:0060216)2.62573746
128cilium or flagellum-dependent cell motility (GO:0001539)2.62186281
129epithelial cilium movement (GO:0003351)2.60205498
130protein localization to endoplasmic reticulum (GO:0070972)2.59967154
131RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.59889099
132regulation of telomere maintenance (GO:0032204)2.59433635
133cilium organization (GO:0044782)2.59378702
134guanosine-containing compound biosynthetic process (GO:1901070)2.58378726
135regulation of male gonad development (GO:2000018)2.57647086
136RNA methylation (GO:0001510)2.56756627
137regulation of action potential (GO:0098900)2.56678452
138cilium assembly (GO:0042384)2.56114057
139DNA deamination (GO:0045006)2.55839664
140positive regulation of defense response to virus by host (GO:0002230)2.55562789
141dopamine transport (GO:0015872)2.55362445
142CTP metabolic process (GO:0046036)2.55219321
143CTP biosynthetic process (GO:0006241)2.55219321
144maturation of 5.8S rRNA (GO:0000460)2.54877576
145viral protein processing (GO:0019082)2.54816396
146GPI anchor biosynthetic process (GO:0006506)2.54688961
147negative regulation of cytosolic calcium ion concentration (GO:0051481)2.53018393
148sperm motility (GO:0030317)2.52560756
149somite development (GO:0061053)2.51919698
150neural tube formation (GO:0001841)2.51884609
151chromosome organization involved in meiosis (GO:0070192)2.51811384
152establishment of protein localization to endoplasmic reticulum (GO:0072599)2.50879180
153rRNA catabolic process (GO:0016075)2.49731561
154synaptic transmission, cholinergic (GO:0007271)2.49306857
155negative regulation of cAMP-mediated signaling (GO:0043951)2.48245012
156GMP metabolic process (GO:0046037)2.47503841
157cellular response to interferon-beta (GO:0035458)2.47404813
158establishment of protein localization to mitochondrial membrane (GO:0090151)2.46131031
159magnesium ion transport (GO:0015693)2.46117537
160sphingoid metabolic process (GO:0046519)2.45564294
161eye photoreceptor cell development (GO:0042462)2.44796130
162meiotic chromosome segregation (GO:0045132)2.44677386
163positive regulation of meiosis (GO:0045836)2.43638130
164positive regulation of megakaryocyte differentiation (GO:0045654)2.42479919
165recombinational repair (GO:0000725)2.42277038
166response to interferon-beta (GO:0035456)2.42120957
167double-strand break repair via homologous recombination (GO:0000724)2.42014670
168peptidyl-histidine modification (GO:0018202)2.40888325
169facial nerve structural organization (GO:0021612)2.40809315
170cilium morphogenesis (GO:0060271)2.40426214
171purinergic nucleotide receptor signaling pathway (GO:0035590)2.39941303
172positive regulation of icosanoid secretion (GO:0032305)2.39883944
173aerobic respiration (GO:0009060)2.39744626
174tRNA modification (GO:0006400)2.38930836
175tRNA processing (GO:0008033)2.37112566
176viral life cycle (GO:0019058)2.36872477
177poly(A)+ mRNA export from nucleus (GO:0016973)2.35773730
178cilium movement (GO:0003341)2.35303366
179cranial nerve morphogenesis (GO:0021602)2.32457103
180positive regulation of meiotic cell cycle (GO:0051446)2.31232855
181regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.29786746

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.31203218
2ZNF274_21170338_ChIP-Seq_K562_Hela4.14648191
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.55575189
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.96536185
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.95883881
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.85880603
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.79849533
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.77090004
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.66511067
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.65071784
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.53777584
12TAF15_26573619_Chip-Seq_HEK293_Human2.44574852
13GBX2_23144817_ChIP-Seq_PC3_Human2.44389634
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.34396655
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.23617236
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.21870521
17POU3F2_20337985_ChIP-ChIP_501MEL_Human2.21363130
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17161167
19* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.09309322
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.04937533
21VDR_22108803_ChIP-Seq_LS180_Human1.99760409
22BCAT_22108803_ChIP-Seq_LS180_Human1.96673063
23RNF2_27304074_Chip-Seq_NSC_Mouse1.95731637
24SUZ12_27294783_Chip-Seq_NPCs_Mouse1.95443172
25GABP_17652178_ChIP-ChIP_JURKAT_Human1.90408260
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.89302463
27EST1_17652178_ChIP-ChIP_JURKAT_Human1.88606972
28PCGF2_27294783_Chip-Seq_NPCs_Mouse1.87676613
29NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.87287188
30IRF1_19129219_ChIP-ChIP_H3396_Human1.87104648
31IRF8_22096565_ChIP-ChIP_GC-B_Human1.85462104
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.73624354
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.70487945
34TP53_22573176_ChIP-Seq_HFKS_Human1.67803724
35JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.67136329
36IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.65988917
37CBP_20019798_ChIP-Seq_JUKART_Human1.65988917
38ELF1_17652178_ChIP-ChIP_JURKAT_Human1.65773416
39UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.64255586
40FUS_26573619_Chip-Seq_HEK293_Human1.63504712
41SALL1_21062744_ChIP-ChIP_HESCs_Human1.62047740
42AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.58827309
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.58347764
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.58231715
45JARID2_20064375_ChIP-Seq_MESCs_Mouse1.53783580
46SUZ12_18555785_Chip-Seq_ESCs_Mouse1.53621618
47STAT3_18555785_Chip-Seq_ESCs_Mouse1.51169658
48P53_22387025_ChIP-Seq_ESCs_Mouse1.49364393
49NANOG_18555785_Chip-Seq_ESCs_Mouse1.48923658
50P300_19829295_ChIP-Seq_ESCs_Human1.48845713
51NANOG_19829295_ChIP-Seq_ESCs_Human1.48458714
52SOX2_19829295_ChIP-Seq_ESCs_Human1.48458714
53NMYC_18555785_Chip-Seq_ESCs_Mouse1.48452189
54EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.48411751
55SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.48005532
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.47012676
57POU5F1_16153702_ChIP-ChIP_HESCs_Human1.47003874
58TAL1_26923725_Chip-Seq_HPCs_Mouse1.44325858
59STAT3_23295773_ChIP-Seq_U87_Human1.43963500
60PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.43683654
61EZH2_27304074_Chip-Seq_ESCs_Mouse1.42025953
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.41810048
63* SRF_21415370_ChIP-Seq_HL-1_Mouse1.40001361
64E2F1_18555785_Chip-Seq_ESCs_Mouse1.39431868
65P300_18555785_Chip-Seq_ESCs_Mouse1.39366135
66TCF4_23295773_ChIP-Seq_U87_Human1.39252249
67CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39225920
68RUNX1_27457419_Chip-Seq_LIVER_Mouse1.38556102
69SMAD4_21799915_ChIP-Seq_A2780_Human1.36038031
70CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35357852
71TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.34967249
72GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.34713651
73MYC_18940864_ChIP-ChIP_HL60_Human1.34324330
74FOXA1_27270436_Chip-Seq_PROSTATE_Human1.33952402
75FOXA1_25329375_ChIP-Seq_VCAP_Human1.33952402
76MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33319363
77EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.31433140
78AR_25329375_ChIP-Seq_VCAP_Human1.31328914
79* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.31076400
80KLF5_20875108_ChIP-Seq_MESCs_Mouse1.30779499
81CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30271756
82EED_16625203_ChIP-ChIP_MESCs_Mouse1.28742805
83NR3C1_21868756_ChIP-Seq_MCF10A_Human1.28674878
84SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.27990555
85CMYC_18555785_Chip-Seq_ESCs_Mouse1.27583494
86EWS_26573619_Chip-Seq_HEK293_Human1.27173227
87CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.26542875
88GATA3_21878914_ChIP-Seq_MCF-7_Human1.25564763
89FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.25289724
90PIAS1_25552417_ChIP-Seq_VCAP_Human1.24707735
91IKZF1_21737484_ChIP-ChIP_HCT116_Human1.24244637
92IGF1R_20145208_ChIP-Seq_DFB_Human1.24221894
93TP63_19390658_ChIP-ChIP_HaCaT_Human1.24019347
94RBPJ_22232070_ChIP-Seq_NCS_Mouse1.24012074
95ZFX_18555785_Chip-Seq_ESCs_Mouse1.23570315
96FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.22935290
97OCT4_18555785_Chip-Seq_ESCs_Mouse1.22708886
98PRDM14_20953172_ChIP-Seq_ESCs_Human1.22519554
99SOX2_18555785_Chip-Seq_ESCs_Mouse1.22375131
100SMAD4_21741376_ChIP-Seq_EPCs_Human1.22243031
101* VDR_23849224_ChIP-Seq_CD4+_Human1.22216460
102TCF4_22108803_ChIP-Seq_LS180_Human1.22127818
103IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.21396627
104NCOR_22424771_ChIP-Seq_293T_Human1.20136761
105TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19510738
106AR_20517297_ChIP-Seq_VCAP_Human1.19426789
107KLF4_18555785_Chip-Seq_ESCs_Mouse1.18949298
108SMAD1_18555785_Chip-Seq_ESCs_Mouse1.18055459
109REST_21632747_ChIP-Seq_MESCs_Mouse1.17994892
110POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17976734
111TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17976734
112CTCF_18555785_Chip-Seq_ESCs_Mouse1.17728324
113ETV2_25802403_ChIP-Seq_MESCs_Mouse1.16596589
114EGR1_23403033_ChIP-Seq_LIVER_Mouse1.14967874
115SMAD_19615063_ChIP-ChIP_OVARY_Human1.14909726
116CRX_20693478_ChIP-Seq_RETINA_Mouse1.14181661
117CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13625244
118RUNX2_22187159_ChIP-Seq_PCA_Human1.13601818
119FLI1_21867929_ChIP-Seq_TH2_Mouse1.13590333
120PU1_27457419_Chip-Seq_LIVER_Mouse1.13153632
121ER_23166858_ChIP-Seq_MCF-7_Human1.11495731
122HOXB7_26014856_ChIP-Seq_BT474_Human1.10434396
123ELK1_19687146_ChIP-ChIP_HELA_Human1.10294555
124CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.09892203
125ESRRB_18555785_Chip-Seq_ESCs_Mouse1.09576662
126CDX2_22108803_ChIP-Seq_LS180_Human1.08920143
127RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.08519561
128* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.07778538
129EZH2_27294783_Chip-Seq_ESCs_Mouse1.07444156
130YY1_21170310_ChIP-Seq_MESCs_Mouse1.06953944
131IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.05731513
132CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.05476745
133TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05463923
134SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.05099254
135PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.04843730
136OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04439418
137SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.04380173
138FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03569209
139NOTCH1_21737748_ChIP-Seq_TLL_Human1.03062846
140ETS1_20019798_ChIP-Seq_JURKAT_Human1.01572920
141LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.01233693
142CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.00722361
143SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.00350399
144AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99794528
145GATA3_26560356_Chip-Seq_TH2_Human0.99466522
146ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.99357838
147EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99128944
148JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99007891
149RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97991379
150HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97148956
151* FOXP3_21729870_ChIP-Seq_TREG_Human0.94436078
152PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.93805709
153SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.93218140
154KAP1_22055183_ChIP-Seq_ESCs_Mouse0.93174117
155SMAD3_21741376_ChIP-Seq_EPCs_Human0.93066089

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode5.01234476
2MP0001188_hyperpigmentation3.58665287
3MP0003136_yellow_coat_color3.54907653
4MP0009379_abnormal_foot_pigmentation3.20145089
5MP0003880_abnormal_central_pattern3.01156360
6MP0000569_abnormal_digit_pigmentation2.92940632
7MP0003195_calcinosis2.85902432
8MP0002009_preneoplasia2.68470724
9MP0004043_abnormal_pH_regulation2.54252701
10MP0004381_abnormal_hair_follicle2.38524982
11MP0001986_abnormal_taste_sensitivity2.24101520
12MP0002822_catalepsy2.24016265
13MP0005409_darkened_coat_color2.19412858
14MP0005377_hearing/vestibular/ear_phenot2.17260032
15MP0003878_abnormal_ear_physiology2.17260032
16MP0002638_abnormal_pupillary_reflex2.11289543
17MP0001984_abnormal_olfaction2.08504945
18MP0008789_abnormal_olfactory_epithelium2.06528037
19MP0008877_abnormal_DNA_methylation1.83908600
20MP0009046_muscle_twitch1.79623030
21MP0003787_abnormal_imprinting1.77738792
22MP0002837_dystrophic_cardiac_calcinosis1.74650453
23MP0003315_abnormal_perineum_morphology1.70935016
24MP0000015_abnormal_ear_pigmentation1.70316102
25MP0002277_abnormal_respiratory_mucosa1.69962612
26MP0002138_abnormal_hepatobiliary_system1.67897366
27MP0000372_irregular_coat_pigmentation1.66934643
28MP0005394_taste/olfaction_phenotype1.65592981
29MP0005499_abnormal_olfactory_system1.65592981
30MP0000566_synostosis1.64953044
31MP0005551_abnormal_eye_electrophysiolog1.64241724
32MP0008872_abnormal_physiological_respon1.60899423
33MP0002876_abnormal_thyroid_physiology1.58987623
34MP0002751_abnormal_autonomic_nervous1.58277443
35MP0006072_abnormal_retinal_apoptosis1.57470335
36MP0005174_abnormal_tail_pigmentation1.55295166
37MP0005645_abnormal_hypothalamus_physiol1.53984393
38MP0005075_abnormal_melanosome_morpholog1.52727865
39MP0003941_abnormal_skin_development1.48665199
40MP0005083_abnormal_biliary_tract1.48543561
41MP0006276_abnormal_autonomic_nervous1.45682883
42MP0002160_abnormal_reproductive_system1.43371392
43MP0001485_abnormal_pinna_reflex1.40493112
44MP0001529_abnormal_vocalization1.38093642
45MP0000631_abnormal_neuroendocrine_gland1.34986807
46MP0008058_abnormal_DNA_repair1.34665538
47MP0002095_abnormal_skin_pigmentation1.33007824
48MP0000427_abnormal_hair_cycle1.32073048
49MP0003724_increased_susceptibility_to1.29147089
50MP0002928_abnormal_bile_duct1.28648831
51MP0004885_abnormal_endolymph1.26308931
52MP0004142_abnormal_muscle_tone1.24625405
53MP0005253_abnormal_eye_physiology1.22232605
54MP0008875_abnormal_xenobiotic_pharmacok1.20324026
55MP0001905_abnormal_dopamine_level1.18537590
56MP0002163_abnormal_gland_morphology1.15845515
57MP0005187_abnormal_penis_morphology1.15841625
58MP0009697_abnormal_copulation1.15413783
59MP0001968_abnormal_touch/_nociception1.14957079
60MP0000678_abnormal_parathyroid_gland1.14549734
61MP0000026_abnormal_inner_ear1.13436267
62MP0002653_abnormal_ependyma_morphology1.12648754
63MP0005389_reproductive_system_phenotype1.12605553
64MP0005171_absent_coat_pigmentation1.11970320
65MP0005646_abnormal_pituitary_gland1.11960559
66MP0003786_premature_aging1.11734611
67MP0001919_abnormal_reproductive_system1.11516580
68MP0008057_abnormal_DNA_replication1.10008595
69MP0002272_abnormal_nervous_system1.09779698
70MP0000049_abnormal_middle_ear1.09139293
71MP0004147_increased_porphyrin_level1.07950292
72MP0001486_abnormal_startle_reflex1.07558709
73MP0002249_abnormal_larynx_morphology1.07524233
74MP0002210_abnormal_sex_determination1.07444783
75MP0000538_abnormal_urinary_bladder1.06677294
76MP0001963_abnormal_hearing_physiology1.05586538
77MP0008995_early_reproductive_senescence1.04444889
78MP0002938_white_spotting1.04312084
79MP0002148_abnormal_hypersensitivity_rea1.03151135
80MP0005671_abnormal_response_to1.03133399
81MP0010386_abnormal_urinary_bladder1.02303794
82MP0003011_delayed_dark_adaptation1.01404165
83MP0004924_abnormal_behavior1.01238534
84MP0005386_behavior/neurological_phenoty1.01238534
85MP0002132_abnormal_respiratory_system0.99238680
86MP0002736_abnormal_nociception_after0.98837799
87MP0002735_abnormal_chemical_nociception0.98590819
88MP0005195_abnormal_posterior_eye0.98400510
89MP0002067_abnormal_sensory_capabilities0.98022278
90MP0000681_abnormal_thyroid_gland0.97895165
91MP0001970_abnormal_pain_threshold0.97294250
92MP0003283_abnormal_digestive_organ0.97138458
93MP0002102_abnormal_ear_morphology0.96625718
94MP0004742_abnormal_vestibular_system0.96364271
95MP0005084_abnormal_gallbladder_morpholo0.96315604
96MP0002557_abnormal_social/conspecific_i0.96174964
97MP0003252_abnormal_bile_duct0.95837319
98MP0005379_endocrine/exocrine_gland_phen0.95003787
99MP0002234_abnormal_pharynx_morphology0.94623183
100MP0001501_abnormal_sleep_pattern0.93065659
101MP0003938_abnormal_ear_development0.92965687
102MP0000516_abnormal_urinary_system0.92544644
103MP0005367_renal/urinary_system_phenotyp0.92544644
104MP0003763_abnormal_thymus_physiology0.91847436
105MP0002733_abnormal_thermal_nociception0.90876645
106MP0003698_abnormal_male_reproductive0.90327419
107MP0002752_abnormal_somatic_nervous0.89764546
108MP0004782_abnormal_surfactant_physiolog0.88039064
109MP0003693_abnormal_embryo_hatching0.87867112
110MP0001324_abnormal_eye_pigmentation0.85632907
111MP0002177_abnormal_outer_ear0.85587630
112MP0000230_abnormal_systemic_arterial0.84971089
113MP0008260_abnormal_autophagy0.84632864
114MP0001145_abnormal_male_reproductive0.83948584
115MP0003879_abnormal_hair_cell0.83437711
116MP0000490_abnormal_crypts_of0.83254833
117MP0003121_genomic_imprinting0.82929012
118MP0001929_abnormal_gametogenesis0.82648288
119MP0009745_abnormal_behavioral_response0.82407074
120MP0000647_abnormal_sebaceous_gland0.82336318
121MP0009764_decreased_sensitivity_to0.82213440
122MP0002572_abnormal_emotion/affect_behav0.82164193
123MP0009250_abnormal_appendicular_skeleto0.80876028
124MP0005085_abnormal_gallbladder_physiolo0.80759148
125MP0002254_reproductive_system_inflammat0.78244439
126MP0005408_hypopigmentation0.78234799
127MP0004145_abnormal_muscle_electrophysio0.78041433
128MP0000613_abnormal_salivary_gland0.78026942
129MP0000685_abnormal_immune_system0.77297514
130MP0004215_abnormal_myocardial_fiber0.76672624
131MP0005332_abnormal_amino_acid0.76428517
132MP0002064_seizures0.76169793
133MP0002229_neurodegeneration0.75969512
134MP0003866_abnormal_defecation0.75929226
135MP0009785_altered_susceptibility_to0.75670870
136MP0005365_abnormal_bile_salt0.75000692
137MP0005410_abnormal_fertilization0.74548607
138MP0001119_abnormal_female_reproductive0.73070715
139MP0003718_maternal_effect0.72607969
140MP0003646_muscle_fatigue0.72533804
141MP0000653_abnormal_sex_gland0.72521415
142MP0005423_abnormal_somatic_nervous0.69900917

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.15154238
2Mitochondrial inheritance (HP:0001427)3.95345255
3Increased hepatocellular lipid droplets (HP:0006565)3.81903697
4Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.71159617
5Progressive macrocephaly (HP:0004481)3.63959862
6Renal Fanconi syndrome (HP:0001994)3.53510861
7Abnormal mitochondria in muscle tissue (HP:0008316)3.52005242
8Delayed CNS myelination (HP:0002188)3.42311607
9Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.38071467
10Hepatocellular necrosis (HP:0001404)3.27830949
11Type II lissencephaly (HP:0007260)3.27151221
12Abnormality of the renal cortex (HP:0011035)3.22433276
13Type I transferrin isoform profile (HP:0003642)3.20276681
14Increased CSF lactate (HP:0002490)3.19540986
15Optic disc pallor (HP:0000543)3.09517149
16Abnormality of the renal medulla (HP:0100957)3.08569587
17Lipid accumulation in hepatocytes (HP:0006561)3.08399926
18Acute encephalopathy (HP:0006846)3.03904262
19True hermaphroditism (HP:0010459)3.00738846
20Absent/shortened dynein arms (HP:0200106)2.96897494
21Dynein arm defect of respiratory motile cilia (HP:0012255)2.96897494
22Fair hair (HP:0002286)2.93575907
23Medial flaring of the eyebrow (HP:0010747)2.92974602
24Short tibia (HP:0005736)2.91040822
25Congenital, generalized hypertrichosis (HP:0004540)2.90091118
26Aplasia/Hypoplasia of the tibia (HP:0005772)2.85380540
27Abnormal respiratory motile cilium morphology (HP:0005938)2.84090872
28Abnormal respiratory epithelium morphology (HP:0012253)2.84090872
29Cystic liver disease (HP:0006706)2.82245575
30Abnormality of the phalanges of the hallux (HP:0010057)2.82183821
313-Methylglutaconic aciduria (HP:0003535)2.76013850
32Chromsome breakage (HP:0040012)2.72415494
33Exertional dyspnea (HP:0002875)2.71721277
34Attenuation of retinal blood vessels (HP:0007843)2.71073068
35Abnormal ciliary motility (HP:0012262)2.70935466
36Absent rod-and cone-mediated responses on ERG (HP:0007688)2.69937270
37Chromosomal breakage induced by crosslinking agents (HP:0003221)2.65761641
38Abnormality of the phalanges of the 2nd finger (HP:0009541)2.65541518
39Hypothermia (HP:0002045)2.65416990
40Hepatic necrosis (HP:0002605)2.63028931
41Chronic hepatic failure (HP:0100626)2.62417549
42Nephrogenic diabetes insipidus (HP:0009806)2.61778131
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.59200153
44Abnormality of alanine metabolism (HP:0010916)2.59200153
45Hyperalaninemia (HP:0003348)2.59200153
46Aplastic anemia (HP:0001915)2.59166308
47Abolished electroretinogram (ERG) (HP:0000550)2.57389623
48Abnormality of renal resorption (HP:0011038)2.49160113
49Abnormality of the axillary hair (HP:0100134)2.46031539
50Abnormality of secondary sexual hair (HP:0009888)2.46031539
51Tubular atrophy (HP:0000092)2.44724755
52Thyroiditis (HP:0100646)2.44414221
53Increased intramyocellular lipid droplets (HP:0012240)2.43704527
54Respiratory difficulties (HP:0002880)2.43587679
55Congenital primary aphakia (HP:0007707)2.41815410
56Abnormal biliary tract physiology (HP:0012439)2.37435066
57Bile duct proliferation (HP:0001408)2.37435066
58Hypoplasia of the uterus (HP:0000013)2.37030844
59Cerebellar dysplasia (HP:0007033)2.36898669
60Generalized hypopigmentation of hair (HP:0011358)2.36438475
61Abnormal respiratory motile cilium physiology (HP:0012261)2.35625234
62Absent speech (HP:0001344)2.35214285
63Gait imbalance (HP:0002141)2.34811235
64Abnormal rod and cone electroretinograms (HP:0008323)2.33602085
65Abnormality of cells of the erythroid lineage (HP:0012130)2.32586620
66Nonprogressive disorder (HP:0003680)2.31059506
67Abnormal number of erythroid precursors (HP:0012131)2.30740921
68Sclerocornea (HP:0000647)2.30546547
69Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.30377415
70Polydipsia (HP:0001959)2.28898346
71Abnormal drinking behavior (HP:0030082)2.28898346
72Congenital hepatic fibrosis (HP:0002612)2.28406728
73Renal cortical cysts (HP:0000803)2.25681113
74Pancreatic fibrosis (HP:0100732)2.25488648
75Anencephaly (HP:0002323)2.24957785
76Aplasia/Hypoplasia of the tongue (HP:0010295)2.23620197
77Exercise intolerance (HP:0003546)2.23195162
78Gaze-evoked nystagmus (HP:0000640)2.22850133
79Fibular aplasia (HP:0002990)2.21560447
80Hyperventilation (HP:0002883)2.20932247
81Median cleft lip (HP:0000161)2.16825240
82Pancreatic cysts (HP:0001737)2.15003141
83Male pseudohermaphroditism (HP:0000037)2.14434126
84Reticulocytopenia (HP:0001896)2.13772276
85Increased corneal curvature (HP:0100692)2.13537306
86Keratoconus (HP:0000563)2.13537306
87Pendular nystagmus (HP:0012043)2.13025571
88Tubulointerstitial nephritis (HP:0001970)2.12233917
89Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.12144011
90Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.11780165
91Abnormal protein N-linked glycosylation (HP:0012347)2.11780165
92Abnormal protein glycosylation (HP:0012346)2.11780165
93Abnormal glycosylation (HP:0012345)2.11780165
94Stomach cancer (HP:0012126)2.11091360
95Broad-based gait (HP:0002136)2.09683488
96Supernumerary spleens (HP:0009799)2.08298767
97Congenital stationary night blindness (HP:0007642)2.07988612
98Patchy hypopigmentation of hair (HP:0011365)2.05560591
99Abnormality of the preputium (HP:0100587)2.05238816
100Neoplasm of the adrenal cortex (HP:0100641)2.05071750
101Inability to walk (HP:0002540)2.04397333
102Microvesicular hepatic steatosis (HP:0001414)2.03765144
103Febrile seizures (HP:0002373)2.03559805
104Large for gestational age (HP:0001520)2.03196794
105Lissencephaly (HP:0001339)2.02798324
106Increased serum lactate (HP:0002151)2.01827289
107Progressive inability to walk (HP:0002505)2.01573318
108Occipital encephalocele (HP:0002085)2.01101881
109Focal motor seizures (HP:0011153)1.99018011
110Decreased circulating renin level (HP:0003351)1.97360368
111Furrowed tongue (HP:0000221)1.96659460
112Parakeratosis (HP:0001036)1.96553509
113Severe visual impairment (HP:0001141)1.96404796
114Abnormality of the pons (HP:0007361)1.96398666
115Polyuria (HP:0000103)1.94423266
116Bony spicule pigmentary retinopathy (HP:0007737)1.94268579
117Renal tubular dysfunction (HP:0000124)1.93976965
118Protruding tongue (HP:0010808)1.93330570
119Reduced antithrombin III activity (HP:0001976)1.92740665
120Abnormality of the phalanges of the 5th finger (HP:0004213)1.91201475
121Decreased central vision (HP:0007663)1.91192031
122Abnormality of macular pigmentation (HP:0008002)1.89608852
123Progressive cerebellar ataxia (HP:0002073)1.89437444
124Chorioretinal atrophy (HP:0000533)1.88521363
125Lactic acidosis (HP:0003128)1.88383372
126Aplasia/Hypoplasia of the uvula (HP:0010293)1.86504946
127Type 2 muscle fiber atrophy (HP:0003554)1.85762751
128Nephroblastoma (Wilms tumor) (HP:0002667)1.85398599
129Abnormality of dental color (HP:0011073)1.83774253
130Molar tooth sign on MRI (HP:0002419)1.83126706
131Abnormality of midbrain morphology (HP:0002418)1.83126706
132Abnormality of eosinophils (HP:0001879)1.82002721
133Nephronophthisis (HP:0000090)1.81964232
134Retinitis pigmentosa (HP:0000510)1.81685408
135Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.80880588
136Adactyly (HP:0009776)1.80466511
137Postaxial foot polydactyly (HP:0001830)1.80341016
138Postaxial hand polydactyly (HP:0001162)1.80032079
139Aplasia/Hypoplasia of the sacrum (HP:0008517)1.79950382
140Abnormal sex determination (HP:0012244)1.78488648
141Sex reversal (HP:0012245)1.78488648
142Congenital sensorineural hearing impairment (HP:0008527)1.77826161
143Severe combined immunodeficiency (HP:0004430)1.77786421
144Dandy-Walker malformation (HP:0001305)1.77637852
145Meckel diverticulum (HP:0002245)1.76833334
146Severe muscular hypotonia (HP:0006829)1.76744803
147Widely spaced teeth (HP:0000687)1.76620862
148Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.76287720
149Decreased activity of mitochondrial respiratory chain (HP:0008972)1.76287720
150Optic nerve hypoplasia (HP:0000609)1.76152198
151Aganglionic megacolon (HP:0002251)1.76025492
152Vaginal atresia (HP:0000148)1.75822827
153Increased muscle lipid content (HP:0009058)1.75813849
154Hypoplasia of the pons (HP:0012110)1.75782792
155Aplasia/hypoplasia of the uterus (HP:0008684)1.75421026
156Constricted visual fields (HP:0001133)1.75203965
157Hypoproteinemia (HP:0003075)1.74963436
158Clubbing of toes (HP:0100760)1.74937646
159Preaxial hand polydactyly (HP:0001177)1.74910711
160Genital tract atresia (HP:0001827)1.74258781
161Decreased electroretinogram (ERG) amplitude (HP:0000654)1.74245107
162Embryonal renal neoplasm (HP:0011794)1.74018072
163Cerebral edema (HP:0002181)1.73657401
164Poor coordination (HP:0002370)1.73341759
165Hypoplastic left heart (HP:0004383)1.73300707
166Hypoplasia of the fovea (HP:0007750)1.72973169
167Aplasia/Hypoplasia of the fovea (HP:0008060)1.72973169

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.74416709
2CASK3.69979030
3TNIK3.47122849
4MUSK3.29680168
5NME23.01028077
6MKNK23.00833777
7STK162.87964328
8MAP4K22.48463962
9BMPR22.48008748
10PLK22.38708078
11MAP2K72.29726967
12SRPK12.27822530
13TLK12.25373984
14WNK32.19766950
15MKNK12.18361652
16PRPF4B2.16133620
17IRAK32.02943058
18BMPR1B1.95466210
19IRAK41.93863416
20MAP3K121.93697304
21TAOK31.72089058
22CDK31.65677099
23YES11.64699135
24TGFBR11.58328935
25NUAK11.53115717
26GRK71.49313517
27TEC1.45215377
28NEK21.42198466
29TXK1.41408313
30BCR1.37940992
31PIK3CA1.35393990
32PRKCI1.32237579
33CDK191.30427837
34NEK61.24275692
35IRAK21.21025548
36VRK11.17122207
37BRAF1.13765242
38PBK1.13482640
39IRAK11.13331383
40GRK11.13078022
41ZAK1.09750489
42MST1R1.08306722
43AKT31.06821062
44ERBB31.06150394
45FES1.04045852
46STK391.00215157
47MST40.98788000
48NTRK20.98062859
49MAPK150.97093679
50ADRBK20.95795264
51MAPK130.95494475
52ACVR1B0.93427092
53CDK80.89866903
54CLK10.89505380
55DAPK20.89087046
56EIF2AK20.87934488
57STK38L0.87241341
58PINK10.86250984
59BCKDK0.86115920
60MARK10.83329367
61RIPK40.83123879
62NLK0.82919101
63PRKD20.82346173
64IKBKE0.81499479
65SGK20.77980317
66CDK90.76208987
67TRIM280.76063546
68EPHA40.74786044
69PLK40.74659173
70MAP3K60.73071311
71CSNK1G20.73035527
72CAMK2B0.71549945
73PHKG20.70466485
74PHKG10.70466485
75TNK20.70041097
76MYLK0.68915141
77CSNK1G30.66407951
78CAMK2D0.66398292
79PDK20.65709583
80PRKCQ0.65232436
81PAK30.64873224
82INSRR0.64805188
83MAP3K140.64731434
84IKBKB0.64191842
85PIM20.64182871
86TAF10.62243861
87NEK90.61875791
88VRK20.60635829
89PRKCG0.59651074
90RPS6KA50.58473547
91FGFR20.58345799
92WEE10.54914751
93MAP3K70.54706418
94CSNK1A1L0.54186962
95MAPKAPK50.53645847
96DYRK1A0.52684210
97SGK2230.51570838
98SGK4940.51570838
99CAMK2A0.51539965
100CDK70.51478047
101PRKCE0.49796574
102MAPKAPK30.48968109
103EIF2AK30.48600674
104CHUK0.48305526
105STK30.47942297
106ITK0.47933736
107OXSR10.47764294
108OBSCN0.47748585
109FLT30.47723823
110PIK3CG0.47679800
111CCNB10.47538809
112CSNK1A10.47365696
113RPS6KB10.47296682
114CAMK10.46511085
115BRSK20.45715087
116LYN0.44592031
117NTRK30.44206174
118PTK2B0.43155460
119CAMKK20.42846362
120PLK30.42838284
121ADRBK10.42547847
122ATR0.42238497
123PNCK0.41873963
124BTK0.40643107
125PRKG10.39649107
126MAP2K20.39002034
127STK240.38498359
128WNK40.38346597
129NME10.38245666
130PIM10.37658594
131GRK50.37330008
132DYRK20.37187273
133CSNK1G10.37041577
134IGF1R0.36640601
135MAP3K40.36022963
136SGK10.35865757
137LCK0.35450761
138KIT0.35247483
139MAP2K60.33558876
140CSNK2A10.33437988
141DYRK30.32721774
142PRKACB0.32372923
143ATM0.32365390
144PRKACA0.32128265
145SYK0.31767754
146PKN10.31378680
147BRD40.29842370
148TIE10.28064133

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.76210105
2Ribosome_Homo sapiens_hsa030103.65528957
3Parkinsons disease_Homo sapiens_hsa050123.10828356
4Phototransduction_Homo sapiens_hsa047442.96495631
5Huntingtons disease_Homo sapiens_hsa050162.54986880
6RNA polymerase_Homo sapiens_hsa030202.49339592
7Alzheimers disease_Homo sapiens_hsa050102.48184732
8Nitrogen metabolism_Homo sapiens_hsa009102.36992975
9Protein export_Homo sapiens_hsa030602.32488389
10Butanoate metabolism_Homo sapiens_hsa006502.28959851
11Homologous recombination_Homo sapiens_hsa034402.14255297
12Fanconi anemia pathway_Homo sapiens_hsa034602.10705403
13Sulfur metabolism_Homo sapiens_hsa009202.09182529
14Propanoate metabolism_Homo sapiens_hsa006402.05340074
15Tryptophan metabolism_Homo sapiens_hsa003802.01196588
16Basal transcription factors_Homo sapiens_hsa030221.99022912
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.93089069
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.88406438
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.81221613
20Non-homologous end-joining_Homo sapiens_hsa034501.75323088
21Sulfur relay system_Homo sapiens_hsa041221.72254487
22DNA replication_Homo sapiens_hsa030301.69587105
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.66354336
24Arachidonic acid metabolism_Homo sapiens_hsa005901.62531344
25Selenocompound metabolism_Homo sapiens_hsa004501.58659456
26Peroxisome_Homo sapiens_hsa041461.50366138
27Caffeine metabolism_Homo sapiens_hsa002321.48907875
28Sphingolipid metabolism_Homo sapiens_hsa006001.46324814
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.46204854
30Nucleotide excision repair_Homo sapiens_hsa034201.45496843
31Pyrimidine metabolism_Homo sapiens_hsa002401.41400112
32SNARE interactions in vesicular transport_Homo sapiens_hsa041301.41341820
33Cardiac muscle contraction_Homo sapiens_hsa042601.39321748
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.33630835
35Nicotine addiction_Homo sapiens_hsa050331.33566104
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33058194
37Spliceosome_Homo sapiens_hsa030401.28888584
38Mismatch repair_Homo sapiens_hsa034301.27257680
39Proteasome_Homo sapiens_hsa030501.26047180
40Linoleic acid metabolism_Homo sapiens_hsa005911.25007960
41Base excision repair_Homo sapiens_hsa034101.21940431
42RNA degradation_Homo sapiens_hsa030181.21702619
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19688703
44Purine metabolism_Homo sapiens_hsa002301.19525603
45Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.17761721
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.15670318
47Taste transduction_Homo sapiens_hsa047421.15403928
48beta-Alanine metabolism_Homo sapiens_hsa004101.13517502
49Serotonergic synapse_Homo sapiens_hsa047261.08854587
50Ether lipid metabolism_Homo sapiens_hsa005651.08458055
51alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.08088810
52Chemical carcinogenesis_Homo sapiens_hsa052041.04825769
53Primary bile acid biosynthesis_Homo sapiens_hsa001201.03927232
54ABC transporters_Homo sapiens_hsa020101.01486229
55Primary immunodeficiency_Homo sapiens_hsa053400.99629607
56Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.98445284
57Olfactory transduction_Homo sapiens_hsa047400.94493187
58Graft-versus-host disease_Homo sapiens_hsa053320.89091513
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.82936553
60Retinol metabolism_Homo sapiens_hsa008300.80856692
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.80806880
62Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.78021251
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.77668456
64Other glycan degradation_Homo sapiens_hsa005110.76976812
65RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.76062474
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.74375483
67Morphine addiction_Homo sapiens_hsa050320.73048088
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.73022438
69Autoimmune thyroid disease_Homo sapiens_hsa053200.69620839
70Fatty acid elongation_Homo sapiens_hsa000620.69550726
71Glycerolipid metabolism_Homo sapiens_hsa005610.68067715
72Allograft rejection_Homo sapiens_hsa053300.67600324
73Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66560742
74Hematopoietic cell lineage_Homo sapiens_hsa046400.65166704
75Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64162847
76Insulin secretion_Homo sapiens_hsa049110.61405263
77Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.61139336
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.60124710
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59681631
80Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.58979188
81Glutamatergic synapse_Homo sapiens_hsa047240.58616824
82One carbon pool by folate_Homo sapiens_hsa006700.58022068
83NF-kappa B signaling pathway_Homo sapiens_hsa040640.57861914
84Herpes simplex infection_Homo sapiens_hsa051680.56903968
85Asthma_Homo sapiens_hsa053100.55713899
86Long-term depression_Homo sapiens_hsa047300.55386431
87Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54695094
88Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.54124494
89Metabolic pathways_Homo sapiens_hsa011000.52194313
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51062596
91Thyroid cancer_Homo sapiens_hsa052160.50658079
92mRNA surveillance pathway_Homo sapiens_hsa030150.49777427
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49071418
94Fatty acid degradation_Homo sapiens_hsa000710.48890678
95Dorso-ventral axis formation_Homo sapiens_hsa043200.47446368
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.47157345
97Measles_Homo sapiens_hsa051620.46207288
98Regulation of autophagy_Homo sapiens_hsa041400.45212112
99Rheumatoid arthritis_Homo sapiens_hsa053230.42978427
100Mineral absorption_Homo sapiens_hsa049780.40949652
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.40493841
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.40267245
103Circadian rhythm_Homo sapiens_hsa047100.38199597
104Cell cycle_Homo sapiens_hsa041100.37543329
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37499285
106Salivary secretion_Homo sapiens_hsa049700.37262896
107Collecting duct acid secretion_Homo sapiens_hsa049660.36225304
108Histidine metabolism_Homo sapiens_hsa003400.35796766
109Circadian entrainment_Homo sapiens_hsa047130.35692850
110Calcium signaling pathway_Homo sapiens_hsa040200.35532915
111Alcoholism_Homo sapiens_hsa050340.35269879
112Ovarian steroidogenesis_Homo sapiens_hsa049130.34624623
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.34183494
114RNA transport_Homo sapiens_hsa030130.33324221
115African trypanosomiasis_Homo sapiens_hsa051430.32944621
116Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30797255
117Wnt signaling pathway_Homo sapiens_hsa043100.30566429
118Type I diabetes mellitus_Homo sapiens_hsa049400.30534072
119Dopaminergic synapse_Homo sapiens_hsa047280.30363337
120Antigen processing and presentation_Homo sapiens_hsa046120.30243883
121Amphetamine addiction_Homo sapiens_hsa050310.29136533
122Folate biosynthesis_Homo sapiens_hsa007900.27452313
123GABAergic synapse_Homo sapiens_hsa047270.26995967
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.26892569
125Long-term potentiation_Homo sapiens_hsa047200.26065510
126Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.23615379
127Jak-STAT signaling pathway_Homo sapiens_hsa046300.23445766
128N-Glycan biosynthesis_Homo sapiens_hsa005100.22963682
129Epstein-Barr virus infection_Homo sapiens_hsa051690.22441565
130Steroid hormone biosynthesis_Homo sapiens_hsa001400.22223433
131Systemic lupus erythematosus_Homo sapiens_hsa053220.21218055

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