RAI14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fusion of sperm to egg plasma membrane (GO:0007342)5.14474224
2cilium or flagellum-dependent cell motility (GO:0001539)4.74793562
3sperm-egg recognition (GO:0035036)4.70071594
4nuclear pore complex assembly (GO:0051292)4.64546070
5binding of sperm to zona pellucida (GO:0007339)4.64325244
6nuclear pore organization (GO:0006999)4.26410555
7sperm motility (GO:0030317)4.20994748
8acrosome assembly (GO:0001675)4.19304782
9cell-cell recognition (GO:0009988)4.14862129
10piRNA metabolic process (GO:0034587)4.05300454
11synaptonemal complex assembly (GO:0007130)4.03144754
12multicellular organism reproduction (GO:0032504)3.98164961
13synaptonemal complex organization (GO:0070193)3.85786724
14negative regulation of DNA repair (GO:0045738)3.81666855
15cell wall macromolecule metabolic process (GO:0044036)3.79825168
16cell wall macromolecule catabolic process (GO:0016998)3.79825168
17negative regulation of chondrocyte differentiation (GO:0032331)3.75589157
18plasma membrane fusion (GO:0045026)3.74059066
19mitotic sister chromatid cohesion (GO:0007064)3.71441723
20heterochromatin organization (GO:0070828)3.68699042
21paraxial mesoderm development (GO:0048339)3.67501763
22regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.66545589
23male meiosis (GO:0007140)3.66507085
24hippo signaling (GO:0035329)3.50746433
25spermatid development (GO:0007286)3.48145563
26endothelial cell morphogenesis (GO:0001886)3.47098036
27retina vasculature morphogenesis in camera-type eye (GO:0061299)3.46185296
28substrate-dependent cell migration (GO:0006929)3.45797713
29lymphangiogenesis (GO:0001946)3.43995690
30pore complex assembly (GO:0046931)3.42495683
31reproduction (GO:0000003)3.38048280
32chondrocyte proliferation (GO:0035988)3.37731639
33mesenchymal-epithelial cell signaling (GO:0060638)3.30013400
34bone trabecula formation (GO:0060346)3.24966131
35regulation of hippo signaling (GO:0035330)3.24731260
36cell adhesion mediated by integrin (GO:0033627)3.21199166
37axonemal dynein complex assembly (GO:0070286)3.16273672
38kidney mesenchyme development (GO:0072074)3.13823778
39monoubiquitinated protein deubiquitination (GO:0035520)3.11104627
40regulation of centriole replication (GO:0046599)3.08083533
41establishment of apical/basal cell polarity (GO:0035089)3.07700499
42genitalia morphogenesis (GO:0035112)3.06559396
43regulation of SMAD protein import into nucleus (GO:0060390)3.05728740
44epithelial cilium movement (GO:0003351)3.02190343
45positive regulation of macrophage activation (GO:0043032)2.97851023
46notochord development (GO:0030903)2.97845285
47endodermal cell differentiation (GO:0035987)2.97818643
48positive regulation of SMAD protein import into nucleus (GO:0060391)2.96411008
49gene silencing by RNA (GO:0031047)2.96105967
50artery development (GO:0060840)2.94805916
51basement membrane organization (GO:0071711)2.92572105
52substrate adhesion-dependent cell spreading (GO:0034446)2.92099217
53chromosome organization involved in meiosis (GO:0070192)2.91433442
54cellular response to vitamin (GO:0071295)2.90160210
55chromosome condensation (GO:0030261)2.90120014
56motile cilium assembly (GO:0044458)2.90106390
57collagen fibril organization (GO:0030199)2.89163609
58regulation of transforming growth factor beta2 production (GO:0032909)2.86826055
59polarized epithelial cell differentiation (GO:0030859)2.86550426
60cellular response to vitamin D (GO:0071305)2.86194006
61collagen metabolic process (GO:0032963)2.85208348
62chaperone-mediated protein complex assembly (GO:0051131)2.83879936
63negative regulation of axon extension involved in axon guidance (GO:0048843)2.83138792
64acrosome reaction (GO:0007340)2.82979979
65maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.82341758
66regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.82183741
67anterior/posterior axis specification, embryo (GO:0008595)2.81054611
68metanephric mesenchyme development (GO:0072075)2.79908647
69regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.79343961
70ventricular cardiac muscle cell development (GO:0055015)2.78911114
71cell migration involved in heart development (GO:0060973)2.77903656
72COPI coating of Golgi vesicle (GO:0048205)2.77023209
73Golgi transport vesicle coating (GO:0048200)2.77023209
74Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.75824013
75DNA replication-dependent nucleosome organization (GO:0034723)2.75518027
76DNA replication-dependent nucleosome assembly (GO:0006335)2.75518027
77convergent extension (GO:0060026)2.75420270
78dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.73040056
79morphogenesis of an endothelium (GO:0003159)2.72948435
80endothelial tube morphogenesis (GO:0061154)2.72948435
81sequestering of extracellular ligand from receptor (GO:0035581)2.72362018
82collagen catabolic process (GO:0030574)2.71356540
83regulation of posttranscriptional gene silencing (GO:0060147)2.70582308
84regulation of gene silencing by miRNA (GO:0060964)2.70582308
85regulation of gene silencing by RNA (GO:0060966)2.70582308
86negative regulation of cell fate specification (GO:0009996)2.69644593
87planar cell polarity pathway involved in neural tube closure (GO:0090179)2.69193535
88regulation of establishment of planar polarity (GO:0090175)2.67328100
89multicellular organismal macromolecule metabolic process (GO:0044259)2.67007440
90cell migration involved in sprouting angiogenesis (GO:0002042)2.66251587
91skin morphogenesis (GO:0043589)2.66076655
92mitotic nuclear envelope disassembly (GO:0007077)2.65487315
93axon extension involved in axon guidance (GO:0048846)2.64413840
94neuron projection extension involved in neuron projection guidance (GO:1902284)2.64413840
95wound healing, spreading of epidermal cells (GO:0035313)2.63385035
96DNA packaging (GO:0006323)2.62888112
97renal system development (GO:0072001)2.62872181
98endocardial cushion development (GO:0003197)2.62745700
99heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.61644090
100regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.61128216
101regulation of protein polyubiquitination (GO:1902914)2.60629068
102protein localization to chromosome, centromeric region (GO:0071459)2.60228013
103protein retention in ER lumen (GO:0006621)2.59135047
104G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.59058038
105positive regulation of endothelial cell apoptotic process (GO:2000353)2.58997080
106negative regulation of cartilage development (GO:0061037)2.58443273
107muscle cell migration (GO:0014812)2.58222845
108protein heterotrimerization (GO:0070208)2.56563502
109epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.55622584
110microtubule depolymerization (GO:0007019)2.55302666
111wound healing, spreading of cells (GO:0044319)2.55176245
112positive regulation of osteoblast proliferation (GO:0033690)2.54847566
113hemidesmosome assembly (GO:0031581)2.54819294
114regulation of RNA export from nucleus (GO:0046831)2.54291088
115blood vessel maturation (GO:0001955)2.53569060
116single fertilization (GO:0007338)2.53339684
117glomerular visceral epithelial cell development (GO:0072015)2.53014722
118cell-substrate junction assembly (GO:0007044)2.52963829
119membrane disassembly (GO:0030397)2.52875709
120nuclear envelope disassembly (GO:0051081)2.52875709
121mRNA stabilization (GO:0048255)2.52457711
122RNA stabilization (GO:0043489)2.52457711
123establishment of tissue polarity (GO:0007164)2.51800520
124establishment of planar polarity (GO:0001736)2.51800520
125negative regulation of stem cell proliferation (GO:2000647)2.51179840
126cochlea morphogenesis (GO:0090103)2.50730622
127regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.50042327
128multicellular organismal metabolic process (GO:0044236)2.49831898
129regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.49142224
130NLS-bearing protein import into nucleus (GO:0006607)2.48592758
131establishment of monopolar cell polarity (GO:0061162)2.48078706
132establishment or maintenance of monopolar cell polarity (GO:0061339)2.48078706
133extracellular matrix disassembly (GO:0022617)2.47871581
134peptidyl-proline hydroxylation (GO:0019511)2.47558285
135vascular endothelial growth factor signaling pathway (GO:0038084)2.47383100
136meiotic nuclear division (GO:0007126)2.46621838
137negative regulation of keratinocyte proliferation (GO:0010839)2.46295509
138multicellular organismal catabolic process (GO:0044243)2.45344049
139regulation of chondrocyte differentiation (GO:0032330)2.45158785
140embryonic foregut morphogenesis (GO:0048617)2.45082228
141sprouting angiogenesis (GO:0002040)2.44451590
142neural crest cell development (GO:0014032)2.43890249
143protein localization to kinetochore (GO:0034501)2.43179880
144mesodermal cell differentiation (GO:0048333)2.43152511
145regulation of mitotic spindle organization (GO:0060236)2.43021615
146regulation of sister chromatid cohesion (GO:0007063)2.42962058
147chondrocyte development (GO:0002063)2.42860126
148sister chromatid segregation (GO:0000819)2.42610318
149positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.41835559
150positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.41835559
151positive regulation of mitotic sister chromatid separation (GO:1901970)2.41835559
152regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.40564842
153regulation of cardioblast differentiation (GO:0051890)2.40558995
154COPII vesicle coating (GO:0048208)2.40527431
155positive regulation of cartilage development (GO:0061036)2.40135602
156branching involved in salivary gland morphogenesis (GO:0060445)2.39628906
157spermatogenesis (GO:0007283)2.39534924
158mitotic metaphase plate congression (GO:0007080)2.39400335
159fertilization (GO:0009566)2.39305045
160renal filtration (GO:0097205)2.39195519
161outer ear morphogenesis (GO:0042473)2.39016191
162male gamete generation (GO:0048232)2.38941767
163ganglion development (GO:0061548)2.36734090
164negative regulation of axon guidance (GO:1902668)2.36124617
165positive regulation of blood vessel endothelial cell migration (GO:0043536)2.35830790
166glomerular basement membrane development (GO:0032836)2.35152657
167protein hydroxylation (GO:0018126)2.33609812
168epithelial cell-cell adhesion (GO:0090136)2.32941504
169pericardium development (GO:0060039)2.31890759
170mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.31600499
171midgut development (GO:0007494)2.30767145

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse6.52476820
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.65527264
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.57654035
4E2F7_22180533_ChIP-Seq_HELA_Human4.55151507
5PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.59908150
6SALL1_21062744_ChIP-ChIP_HESCs_Human3.16361354
7RBPJ_22232070_ChIP-Seq_NCS_Mouse3.07021350
8TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.95208172
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.91139658
10AR_21909140_ChIP-Seq_LNCAP_Human2.71138494
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.68982723
12TRIM28_21343339_ChIP-Seq_HEK293_Human2.58333496
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.53529645
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.32900760
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.27906671
16NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.19557260
17KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.16596548
18RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.15793678
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.07716889
20EP300_21415370_ChIP-Seq_HL-1_Mouse2.04274933
21STAT6_21828071_ChIP-Seq_BEAS2B_Human1.90711319
22ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.89514034
23KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.88148572
24KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.88148572
25KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.88148572
26CLOCK_20551151_ChIP-Seq_293T_Human1.87281841
27* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.85562967
28TP53_18474530_ChIP-ChIP_U2OS_Human1.82228125
29SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.80508331
30CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.78959969
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.77704979
32SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.76325338
33SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.76325338
34ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.75692924
35* BRD4_25478319_ChIP-Seq_HGPS_Human1.75044544
36CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.74231856
37SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.68893904
38ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.68773380
39STAT3_1855785_ChIP-Seq_MESCs_Mouse1.67757127
40SALL4_18804426_ChIP-ChIP_XEN_Mouse1.65876590
41TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.61368082
42TCF3_18692474_ChIP-Seq_MEFs_Mouse1.60520123
43* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.60096233
44HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.58849267
45POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.51210052
46TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.50818016
47* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.50384860
48CJUN_26792858_Chip-Seq_BT549_Human1.45808532
49* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.44784749
50* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43328649
51MYC_18555785_ChIP-Seq_MESCs_Mouse1.41015067
52KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.40308959
53PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.39980326
54SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39716521
55* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.38324065
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.37267370
57TP53_16413492_ChIP-PET_HCT116_Human1.35783544
58* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.32828141
59* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.32828141
60TBX3_20139965_ChIP-Seq_ESCs_Mouse1.32007455
61* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.31977352
62TBX3_20139965_ChIP-Seq_MESCs_Mouse1.31284380
63MYC_19079543_ChIP-ChIP_MESCs_Mouse1.30793635
64* SOX17_20123909_ChIP-Seq_XEN_Mouse1.30259577
65MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.29479697
66UBF1/2_26484160_Chip-Seq_HMECs_Human1.28418244
67* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.26511440
68ATF3_27146783_Chip-Seq_COLON_Human1.25903374
69E2F1_21310950_ChIP-Seq_MCF-7_Human1.25532950
70PPAR_26484153_Chip-Seq_NCI-H1993_Human1.24773997
71KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24613189
72NANOG_16153702_ChIP-ChIP_HESCs_Human1.24377723
73TP53_22127205_ChIP-Seq_IMR90_Human1.22200554
74* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.21612655
75NFIB_24661679_ChIP-Seq_LUNG_Mouse1.21535771
76* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.20891884
77ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20032721
78FOXO3_23340844_ChIP-Seq_DLD1_Human1.19286601
79TP63_19390658_ChIP-ChIP_HaCaT_Human1.18564292
80GATA2_21666600_ChIP-Seq_HMVEC_Human1.17134092
81TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15533872
82ESR1_21235772_ChIP-Seq_MCF-7_Human1.12481472
83NELFA_20434984_ChIP-Seq_ESCs_Mouse1.12032224
84ZNF263_19887448_ChIP-Seq_K562_Human1.11942533
85* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.11832321
86NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.11611138
87POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10298846
88TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.10033041
89* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.09824909
90EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.09698268
91HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.08801126
92ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.08429627
93ELK3_25401928_ChIP-Seq_HUVEC_Human1.07700252
94P300_27058665_Chip-Seq_ZR-75-30cells_Human1.07014466
95STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.06709958
96ELK1_19687146_ChIP-ChIP_HELA_Human1.06225893
97* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.06117404
98KLF4_18555785_ChIP-Seq_MESCs_Mouse1.05806450
99MYCN_18555785_ChIP-Seq_MESCs_Mouse1.04997222
100PIAS1_25552417_ChIP-Seq_VCAP_Human1.04495482
101ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.04316563
102NANOG_21062744_ChIP-ChIP_HESCs_Human1.02381825
103* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01590959
104SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.99594930
105TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.95409927
106SOX9_26525672_Chip-Seq_HEART_Mouse0.93875808
107FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93324489
108RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.93236620
109* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93005125
110GATA6_25053715_ChIP-Seq_YYC3_Human0.92733697
111TCF4_18268006_ChIP-ChIP_LS174T_Human0.90924775
112POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90402586
113CTNNB1_20460455_ChIP-Seq_HCT116_Human0.90024162
114ZFX_18555785_ChIP-Seq_MESCs_Mouse0.89383183
115YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88747759
116DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88218444
117PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.88188370
118ZFP281_27345836_Chip-Seq_ESCs_Mouse0.87105286
119* NANOG_18692474_ChIP-Seq_MEFs_Mouse0.86963676
120* PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.86714024
121FOXM1_26456572_ChIP-Seq_MCF-7_Human0.86506485
122* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.86145830
123CHD1_26751641_Chip-Seq_LNCaP_Human0.85828980
124RUNX1_27514584_Chip-Seq_MCF-7_Human0.85819865
125* NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.85757674
126OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85452517
127ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.85348451
128* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85070882
129CDX2_19796622_ChIP-Seq_MESCs_Mouse0.85037071
130GATA4_25053715_ChIP-Seq_YYC3_Human0.84985984
131NCOR1_26117541_ChIP-Seq_K562_Human0.84930187
132* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.83293336
133ISL1_27105846_Chip-Seq_CPCs_Mouse0.82839081
134WT1_19549856_ChIP-ChIP_CCG9911_Human0.82779578
135BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.81756793

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.74811666
2MP0008438_abnormal_cutaneous_collagen3.73038249
3MP0005410_abnormal_fertilization3.38548966
4MP0005623_abnormal_meninges_morphology2.89811016
5MP0005275_abnormal_skin_tensile2.84461618
6MP0010352_gastrointestinal_tract_polyps2.69932271
7MP0004272_abnormal_basement_membrane2.57554223
8MP0009053_abnormal_anal_canal2.54640042
9MP0003950_abnormal_plasma_membrane2.47424977
10MP0005503_abnormal_tendon_morphology2.42580846
11MP0010030_abnormal_orbit_morphology2.27197900
12MP0000537_abnormal_urethra_morphology1.94557403
13MP0003566_abnormal_cell_adhesion1.93387541
14MP0001299_abnormal_eye_distance/1.90944601
15MP0005076_abnormal_cell_differentiation1.86901444
16MP0006054_spinal_hemorrhage1.85944438
17MP0003279_aneurysm1.78672565
18MP0005023_abnormal_wound_healing1.78314151
19MP0010368_abnormal_lymphatic_system1.73973879
20MP0002877_abnormal_melanocyte_morpholog1.73679348
21MP0001958_emphysema1.69968135
22MP0003941_abnormal_skin_development1.69529585
23MP0010234_abnormal_vibrissa_follicle1.69337869
24MP0002282_abnormal_trachea_morphology1.66221873
25MP0003385_abnormal_body_wall1.59155360
26MP0003115_abnormal_respiratory_system1.48639199
27MP0000762_abnormal_tongue_morphology1.47608210
28MP0005197_abnormal_uvea_morphology1.43719504
29MP0005257_abnormal_intraocular_pressure1.43223357
30MP0003091_abnormal_cell_migration1.40825085
31MP0008007_abnormal_cellular_replicative1.38773204
32MP0003942_abnormal_urinary_system1.37220224
33MP0000733_abnormal_muscle_development1.36367582
34MP0004197_abnormal_fetal_growth/weight/1.35584412
35MP0002060_abnormal_skin_morphology1.34180279
36MP0010307_abnormal_tumor_latency1.31667654
37MP0000534_abnormal_ureter_morphology1.31232499
38MP0001929_abnormal_gametogenesis1.30783824
39MP0005367_renal/urinary_system_phenotyp1.30251650
40MP0000516_abnormal_urinary_system1.30251650
41MP0002084_abnormal_developmental_patter1.27838910
42MP0009384_cardiac_valve_regurgitation1.27788578
43MP0001849_ear_inflammation1.27548470
44MP0005508_abnormal_skeleton_morphology1.27101968
45MP0003937_abnormal_limbs/digits/tail_de1.26846684
46MP0001293_anophthalmia1.24682924
47MP0001915_intracranial_hemorrhage1.23843673
48MP0004957_abnormal_blastocyst_morpholog1.23656562
49MP0001542_abnormal_bone_strength1.23592998
50MP0001730_embryonic_growth_arrest1.23496815
51MP0003698_abnormal_male_reproductive1.21468473
52MP0009250_abnormal_appendicular_skeleto1.20120304
53MP0002653_abnormal_ependyma_morphology1.16281998
54MP0002086_abnormal_extraembryonic_tissu1.15932353
55MP0005380_embryogenesis_phenotype1.15805274
56MP0001672_abnormal_embryogenesis/_devel1.15805274
57MP0009697_abnormal_copulation1.15102940
58MP0010094_abnormal_chromosome_stability1.14492501
59MP0002697_abnormal_eye_size1.14195825
60MP0000432_abnormal_head_morphology1.14150975
61MP0002254_reproductive_system_inflammat1.13722837
62MP0000428_abnormal_craniofacial_morphol1.13180453
63MP0005171_absent_coat_pigmentation1.12879143
64MP0002210_abnormal_sex_determination1.12533402
65MP0003755_abnormal_palate_morphology1.12219021
66MP0000767_abnormal_smooth_muscle1.12157744
67MP0003984_embryonic_growth_retardation1.12045894
68MP0003111_abnormal_nucleus_morphology1.11631777
69MP0002085_abnormal_embryonic_tissue1.11565397
70MP0002088_abnormal_embryonic_growth/wei1.11112288
71MP0002932_abnormal_joint_morphology1.10330279
72MP0003077_abnormal_cell_cycle1.08729342
73MP0002092_abnormal_eye_morphology1.08622076
74MP0009780_abnormal_chondrocyte_physiolo1.08077185
75MP0003935_abnormal_craniofacial_develop1.07087774
76MP0004233_abnormal_muscle_weight1.05820061
77MP0001879_abnormal_lymphatic_vessel1.05436363
78MP0002295_abnormal_pulmonary_circulatio1.04266313
79MP0000350_abnormal_cell_proliferation1.03782309
80MP0001697_abnormal_embryo_size1.02045356
81MP0002796_impaired_skin_barrier1.01336985
82MP0001286_abnormal_eye_development1.00886373
83MP0008877_abnormal_DNA_methylation0.99813792
84MP0000569_abnormal_digit_pigmentation0.98447148
85MP0003890_abnormal_embryonic-extraembry0.98096746
86MP0002925_abnormal_cardiovascular_devel0.97503397
87MP0001145_abnormal_male_reproductive0.97116760
88MP0003119_abnormal_digestive_system0.96777048
89MP0005595_abnormal_vascular_smooth0.95775398
90MP0000751_myopathy0.95723471
91MP0002108_abnormal_muscle_morphology0.95155037
92MP0009278_abnormal_bone_marrow0.95013875
93MP0002896_abnormal_bone_mineralization0.94286094
94MP0002177_abnormal_outer_ear0.92875020
95MP0002938_white_spotting0.92644541
96MP0002111_abnormal_tail_morphology0.92591492
97MP0001243_abnormal_dermal_layer0.92064031
98MP0005248_abnormal_Harderian_gland0.90333107
99MP0002233_abnormal_nose_morphology0.89454298
100MP0005187_abnormal_penis_morphology0.87315065
101MP0005193_abnormal_anterior_eye0.87265946
102MP0008932_abnormal_embryonic_tissue0.86517519
103MP0003453_abnormal_keratinocyte_physiol0.85273751
104MP0005501_abnormal_skin_physiology0.84652124
105MP0003123_paternal_imprinting0.83083249
106MP0000653_abnormal_sex_gland0.82584980
107MP0001614_abnormal_blood_vessel0.82284531
108MP0002115_abnormal_skeleton_extremities0.80367718
109MP0002109_abnormal_limb_morphology0.80098775
110MP0003693_abnormal_embryo_hatching0.80044355
111MP0003283_abnormal_digestive_organ0.79964885
112MP0008057_abnormal_DNA_replication0.79090625
113MP0002128_abnormal_blood_circulation0.78817759
114MP0004808_abnormal_hematopoietic_stem0.78799821
115MP0001175_abnormal_lung_morphology0.78589899
116MP0002080_prenatal_lethality0.78472759
117MP0000049_abnormal_middle_ear0.78204152
118MP0002116_abnormal_craniofacial_bone0.78183016
119MP0002168_other_aberrant_phenotype0.77952244
120MP0000163_abnormal_cartilage_morphology0.73358555
121MP0000013_abnormal_adipose_tissue0.71161258
122MP0004858_abnormal_nervous_system0.70043145
123MP0002114_abnormal_axial_skeleton0.68965616
124MP0006138_congestive_heart_failure0.67142798

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.18873856
2Vascular tortuosity (HP:0004948)4.35244543
3Premature rupture of membranes (HP:0001788)4.31927263
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.27656429
5Arterial tortuosity (HP:0005116)4.27271828
6Shallow orbits (HP:0000586)3.82219811
7Absent/shortened dynein arms (HP:0200106)3.48638562
8Dynein arm defect of respiratory motile cilia (HP:0012255)3.48638562
9Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.30348544
10Short 4th metacarpal (HP:0010044)3.30348544
11Abnormality of dentin (HP:0010299)3.18671524
12Ankle contracture (HP:0006466)3.14190756
13Atrophic scars (HP:0001075)3.01661696
14Chronic bronchitis (HP:0004469)2.95698246
15Selective tooth agenesis (HP:0001592)2.87961698
16Cerebral aneurysm (HP:0004944)2.74251979
17Cervical subluxation (HP:0003308)2.63914137
18Microglossia (HP:0000171)2.58331991
19Abnormality of the 4th metacarpal (HP:0010012)2.51990541
20Spondylolisthesis (HP:0003302)2.49768309
21Peritonitis (HP:0002586)2.46894462
22Aortic dissection (HP:0002647)2.41883813
23Bladder diverticulum (HP:0000015)2.41216103
24Ulnar bowing (HP:0003031)2.40537858
25Overgrowth (HP:0001548)2.38964735
26Genu recurvatum (HP:0002816)2.34786652
27Absent frontal sinuses (HP:0002688)2.34560443
28Abnormal respiratory motile cilium physiology (HP:0012261)2.33881515
29Type 1 muscle fiber predominance (HP:0003803)2.32672960
30Soft skin (HP:0000977)2.31781018
31Mitral valve prolapse (HP:0001634)2.24107741
32Osteolytic defects of the hand bones (HP:0009699)2.23555928
33Osteolytic defects of the phalanges of the hand (HP:0009771)2.23555928
34Hyperextensible skin (HP:0000974)2.21519705
35Tubular atrophy (HP:0000092)2.19974080
36Broad metatarsal (HP:0001783)2.19516654
37Short nail (HP:0001799)2.18199918
38Syringomyelia (HP:0003396)2.16973563
39Spinal cord lesions (HP:0100561)2.16973563
40Natal tooth (HP:0000695)2.16255647
41Wormian bones (HP:0002645)2.16139445
42Coronal craniosynostosis (HP:0004440)2.15575575
43Neonatal short-limb short stature (HP:0008921)2.15119938
44Aortic aneurysm (HP:0004942)2.13487569
45Bell-shaped thorax (HP:0001591)2.08811113
46Fragile skin (HP:0001030)2.08143908
47Abnormality of the distal phalanx of the thumb (HP:0009617)2.07807879
48Vertebral compression fractures (HP:0002953)2.06690149
49Wrist flexion contracture (HP:0001239)2.06538539
50Abnormal respiratory epithelium morphology (HP:0012253)2.04146372
51Abnormal respiratory motile cilium morphology (HP:0005938)2.04146372
52Deviation of the hallux (HP:0010051)2.03694211
53Spinal rigidity (HP:0003306)2.02463371
54Slender build (HP:0001533)2.01867180
55Abnormality of the nasal mucosa (HP:0000433)2.01298829
56Nasal polyposis (HP:0100582)2.00428643
57Blue sclerae (HP:0000592)2.00071462
58Rhinitis (HP:0012384)1.99968895
59Protruding ear (HP:0000411)1.99760855
60Ectopia lentis (HP:0001083)1.98992237
61Short humerus (HP:0005792)1.98251166
62Deviation of the thumb (HP:0009603)1.97972419
63Hallux valgus (HP:0001822)1.97291039
64Infertility (HP:0000789)1.96216354
65Dilatation of the ascending aorta (HP:0005111)1.95435195
66Increased connective tissue (HP:0009025)1.92551117
67Disproportionate tall stature (HP:0001519)1.91647475
68Breech presentation (HP:0001623)1.90091999
69Abnormality of the acetabulum (HP:0003170)1.89813701
70Mildly elevated creatine phosphokinase (HP:0008180)1.87011290
71Buphthalmos (HP:0000557)1.84683324
72Aortic valve stenosis (HP:0001650)1.84260722
73Bowel diverticulosis (HP:0005222)1.83254994
74Abnormality of the peritoneum (HP:0002585)1.82897380
75Missing ribs (HP:0000921)1.82349074
76Aortic regurgitation (HP:0001659)1.80312126
77Short ribs (HP:0000773)1.79730109
78Aplasia/hypoplasia of the humerus (HP:0006507)1.79300253
79Subacute progressive viral hepatitis (HP:0006572)1.78266561
80Hypoplastic labia majora (HP:0000059)1.77624304
81Broad long bones (HP:0005622)1.76976799
82Male infertility (HP:0003251)1.76595787
83Abnormality of the calcaneus (HP:0008364)1.76027545
84Delayed cranial suture closure (HP:0000270)1.75313237
85Mesomelia (HP:0003027)1.74258627
86Pterygium (HP:0001059)1.73672429
87Mitral regurgitation (HP:0001653)1.72976093
88Proximal placement of thumb (HP:0009623)1.72107410
89Elbow flexion contracture (HP:0002987)1.71972840
90Renal duplication (HP:0000075)1.71515793
91Abnormality of the umbilical cord (HP:0010881)1.71287497
92Biconcave vertebral bodies (HP:0004586)1.70896426
93High pitched voice (HP:0001620)1.70532279
94Abnormal delivery (HP:0001787)1.70500456
95Radial bowing (HP:0002986)1.70191128
96Tibial bowing (HP:0002982)1.69759330
97Bowing of the arm (HP:0006488)1.68762574
98Bowed forearm bones (HP:0003956)1.68762574
99Camptodactyly of toe (HP:0001836)1.68088968
100Knee flexion contracture (HP:0006380)1.67664234
101Limited hip movement (HP:0008800)1.66719612
102Vertebral arch anomaly (HP:0008438)1.66279329
103Arnold-Chiari malformation (HP:0002308)1.66113570
104Lymphangioma (HP:0100764)1.65664233
105Wide anterior fontanel (HP:0000260)1.64793496
106Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.64760926
107Nonimmune hydrops fetalis (HP:0001790)1.64651844
108Rectal prolapse (HP:0002035)1.64321365
109Increased density of long bones (HP:0006392)1.63699241
110Abnormality of the fetal cardiovascular system (HP:0010948)1.63683338
111Abnormal umbilical cord blood vessels (HP:0011403)1.63683338
112Single umbilical artery (HP:0001195)1.63683338
113Hypoventilation (HP:0002791)1.63557239
114Rhizomelia (HP:0008905)1.62475375
115Broad thumb (HP:0011304)1.62338794
116Abnormality of the phalanges of the hallux (HP:0010057)1.61682055
117Aneurysm (HP:0002617)1.61200387
118Abnormality of the labia majora (HP:0012881)1.59523871
119Fused cervical vertebrae (HP:0002949)1.59460530
120Abnormality of the lower motor neuron (HP:0002366)1.59108362
121Inguinal hernia (HP:0000023)1.59060854
122Turricephaly (HP:0000262)1.57838409
123Limb-girdle muscle weakness (HP:0003325)1.57833262
124Tubulointerstitial fibrosis (HP:0005576)1.57454372
125Asymmetry of the thorax (HP:0001555)1.56844843
126Broad phalanx (HP:0006009)1.56432918
127Follicular hyperkeratosis (HP:0007502)1.56364291
128Dislocated radial head (HP:0003083)1.56238778
129Milia (HP:0001056)1.56038335
130Pulmonic stenosis (HP:0001642)1.55015504
131Broad phalanges of the hand (HP:0009768)1.54328051
132Joint laxity (HP:0001388)1.52801726
133Arachnodactyly (HP:0001166)1.51437234
134Long eyelashes (HP:0000527)1.51052044
135Hydroureter (HP:0000072)1.50238272
136Cardiovascular calcification (HP:0011915)1.48855779
137Flat cornea (HP:0007720)1.48685539
138Congenital glaucoma (HP:0001087)1.45919033
139Ankyloglossia (HP:0010296)1.45671221
140Joint contractures involving the joints of the feet (HP:0100492)1.45204242
141Flexion contracture of toe (HP:0005830)1.45204242
142Hip contracture (HP:0003273)1.44950314
143Trismus (HP:0000211)1.44184773
144Abnormality of oral frenula (HP:0000190)1.44063305
145Hyperacusis (HP:0010780)1.43445510

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK33.66260986
2PDK43.66260986
3LATS13.43541616
4TESK12.88525015
5MYLK2.75355017
6CDK122.64910746
7PDK22.62166417
8NTRK12.47403938
9DDR22.47233594
10EPHA22.30444132
11NEK22.18895818
12TTN2.07218813
13STK32.07007498
14LATS22.06315584
15CDC71.96390701
16PDGFRA1.95556793
17ICK1.92679489
18TRIB31.88877186
19EPHB21.86328499
20PAK41.79910720
21PKN21.70373820
22LIMK11.64305227
23PRKD31.62386797
24STK38L1.54554548
25TTK1.53691438
26PTK2B1.53216101
27PTK61.51768890
28TGFBR11.51221641
29MET1.48128762
30RIPK11.47739204
31EEF2K1.45226475
32BMX1.39708210
33PAK21.39099838
34CDK61.37507935
35STK101.27018893
36MTOR1.26962078
37BCR1.23363839
38LRRK21.23011321
39WEE11.22120798
40FER1.21847682
41MAP3K101.21828348
42PTK21.21598077
43PBK1.19956622
44TSSK61.16609772
45RPS6KA41.14697111
46DYRK1B1.13809678
47PLK21.11806634
48FGFR11.07692146
49EIF2AK11.07084690
50CDK81.06378171
51TAF11.04472491
52SIK11.02630447
53MOS1.01883557
54RPS6KB21.01248329
55AKT31.00560082
56SRPK10.99953972
57PASK0.98778147
58MKNK20.96707416
59MKNK10.95117951
60DMPK0.92669126
61PLK10.91515617
62PDGFRB0.89887498
63CDK70.89343459
64ROCK20.88940067
65KSR10.88765139
66ERN10.87988210
67NEK90.86864580
68FGFR20.85954086
69TNIK0.82961404
70BRSK10.81931481
71FRK0.80198801
72MAP3K80.79685118
73MST1R0.79662114
74TIE10.79278658
75AURKB0.78850357
76ATR0.77476131
77TYRO30.77311890
78EIF2AK30.75769703
79TGFBR20.75765507
80CHEK10.74624742
81ERBB30.73872845
82KDR0.72031072
83TRPM70.70630706
84BRSK20.66571741
85CHEK20.66450887
86NEK10.64968915
87PLK30.63980232
88CAMK1D0.63888925
89PNCK0.63689858
90CDK40.63652494
91MAP3K30.63470709
92ATM0.63336585
93CLK10.59397822
94DYRK30.58747756
95PAK60.57393139
96TRIM280.56308908
97BRD40.56033701
98PLK40.54754506
99ACVR1B0.54536205
100CAMK1G0.53761959
101EPHA30.52464980
102STK240.51082851
103CDK90.50437853
104MELK0.49810782
105ABL20.49604557
106STK380.48970703
107PAK10.47789454
108SCYL20.47347505
109ERBB40.46587604
110SMG10.46448938
111PRKG20.46443322
112PRKD20.46150149
113CHUK0.45857696
114BUB10.44624727
115ERBB20.42625392
116CDK20.41151038
117PIM10.41109565
118PRKCE0.40950553
119BRAF0.39217537
120MAP3K120.38541977
121IRAK30.36401303
122RPS6KA20.36247493
123WNK40.35895812
124GSK3A0.35717506
125DAPK30.34619237
126EIF2AK20.33283009
127WNK10.33197687
128PAK30.33063378
129INSR0.32606046
130CSNK1G10.32509556
131EGFR0.32198980
132CDK10.31686146
133* MAPK10.31424984
134TESK20.31077136
135FLT30.30798889
136ILK0.29966049
137AURKA0.29343905
138ROCK10.29336235

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.78068968
2Adherens junction_Homo sapiens_hsa045202.47501161
3Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005342.36255803
4Small cell lung cancer_Homo sapiens_hsa052222.18432623
5Hippo signaling pathway_Homo sapiens_hsa043902.08993219
6Basal cell carcinoma_Homo sapiens_hsa052172.08498639
7RNA transport_Homo sapiens_hsa030132.08076255
8Selenocompound metabolism_Homo sapiens_hsa004501.97359820
9Focal adhesion_Homo sapiens_hsa045101.96899616
10Cell cycle_Homo sapiens_hsa041101.93966658
11Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.88966290
12p53 signaling pathway_Homo sapiens_hsa041151.88401118
13One carbon pool by folate_Homo sapiens_hsa006701.85690724
14TGF-beta signaling pathway_Homo sapiens_hsa043501.83367085
15MicroRNAs in cancer_Homo sapiens_hsa052061.79462894
16Proteoglycans in cancer_Homo sapiens_hsa052051.78721154
17Non-homologous end-joining_Homo sapiens_hsa034501.70598917
18Protein export_Homo sapiens_hsa030601.66411669
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.66198174
20Hedgehog signaling pathway_Homo sapiens_hsa043401.64814762
21Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.55504801
22Bladder cancer_Homo sapiens_hsa052191.53255808
23Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.48002855
24mRNA surveillance pathway_Homo sapiens_hsa030151.37006344
25Amoebiasis_Homo sapiens_hsa051461.36404049
26Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.36162741
27Tight junction_Homo sapiens_hsa045301.32904067
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.32885560
29Dilated cardiomyopathy_Homo sapiens_hsa054141.30213622
30Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.27931126
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.27867138
32Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.18582399
33Viral carcinogenesis_Homo sapiens_hsa052031.17466163
34DNA replication_Homo sapiens_hsa030301.15680734
35AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.14381353
36Fatty acid biosynthesis_Homo sapiens_hsa000611.11521223
37Protein digestion and absorption_Homo sapiens_hsa049741.10377962
38HTLV-I infection_Homo sapiens_hsa051661.10124036
39Axon guidance_Homo sapiens_hsa043601.09208398
40Complement and coagulation cascades_Homo sapiens_hsa046101.05017943
41Spliceosome_Homo sapiens_hsa030401.04095264
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02907284
43Mismatch repair_Homo sapiens_hsa034301.01578077
44PI3K-Akt signaling pathway_Homo sapiens_hsa041511.01468670
45Melanogenesis_Homo sapiens_hsa049161.01226629
46N-Glycan biosynthesis_Homo sapiens_hsa005101.01192933
47Basal transcription factors_Homo sapiens_hsa030221.00361356
48Central carbon metabolism in cancer_Homo sapiens_hsa052301.00280940
49Fanconi anemia pathway_Homo sapiens_hsa034601.00075129
50Chronic myeloid leukemia_Homo sapiens_hsa052200.99915980
51Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.99408135
52Prostate cancer_Homo sapiens_hsa052150.96570948
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.96392411
54Pathways in cancer_Homo sapiens_hsa052000.94571867
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.94130135
56Leukocyte transendothelial migration_Homo sapiens_hsa046700.94079375
57Dorso-ventral axis formation_Homo sapiens_hsa043200.92418681
58Malaria_Homo sapiens_hsa051440.92415290
59Thyroid cancer_Homo sapiens_hsa052160.92144869
60Lysine degradation_Homo sapiens_hsa003100.90812710
61Wnt signaling pathway_Homo sapiens_hsa043100.88213605
62Steroid biosynthesis_Homo sapiens_hsa001000.87184266
63Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86818852
64Notch signaling pathway_Homo sapiens_hsa043300.86804939
65Viral myocarditis_Homo sapiens_hsa054160.86512144
66Oocyte meiosis_Homo sapiens_hsa041140.85618166
67Legionellosis_Homo sapiens_hsa051340.83773612
68Systemic lupus erythematosus_Homo sapiens_hsa053220.82806736
69Renin-angiotensin system_Homo sapiens_hsa046140.82546907
70Antigen processing and presentation_Homo sapiens_hsa046120.82419272
71Regulation of actin cytoskeleton_Homo sapiens_hsa048100.82047105
72Melanoma_Homo sapiens_hsa052180.81211792
73Toxoplasmosis_Homo sapiens_hsa051450.81149470
74Nucleotide excision repair_Homo sapiens_hsa034200.79371011
75Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.74840963
76Shigellosis_Homo sapiens_hsa051310.73118348
77Pyruvate metabolism_Homo sapiens_hsa006200.71348982
78Base excision repair_Homo sapiens_hsa034100.69991328
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.69432445
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.69144233
81Gap junction_Homo sapiens_hsa045400.68032235
82Glucagon signaling pathway_Homo sapiens_hsa049220.67766406
83Chemical carcinogenesis_Homo sapiens_hsa052040.67054476
84mTOR signaling pathway_Homo sapiens_hsa041500.64693631
85Galactose metabolism_Homo sapiens_hsa000520.64691199
86Nitrogen metabolism_Homo sapiens_hsa009100.64536956
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64512196
88Proteasome_Homo sapiens_hsa030500.63742232
89Caffeine metabolism_Homo sapiens_hsa002320.62218639
90Biosynthesis of amino acids_Homo sapiens_hsa012300.61925431
91Glioma_Homo sapiens_hsa052140.60939108
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60880959
93Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.60831750
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.60798498
95Rap1 signaling pathway_Homo sapiens_hsa040150.60786118
96Endometrial cancer_Homo sapiens_hsa052130.59569199
97Vitamin B6 metabolism_Homo sapiens_hsa007500.59530747
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58947468
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58419626
100RNA degradation_Homo sapiens_hsa030180.57896304
101Thyroid hormone synthesis_Homo sapiens_hsa049180.57201719
102Mineral absorption_Homo sapiens_hsa049780.57185491
103Linoleic acid metabolism_Homo sapiens_hsa005910.56991461
104PPAR signaling pathway_Homo sapiens_hsa033200.56984263
105VEGF signaling pathway_Homo sapiens_hsa043700.56456341
106Pancreatic cancer_Homo sapiens_hsa052120.56429237
107Colorectal cancer_Homo sapiens_hsa052100.56157470
108TNF signaling pathway_Homo sapiens_hsa046680.55718083
109Epstein-Barr virus infection_Homo sapiens_hsa051690.55349128
110HIF-1 signaling pathway_Homo sapiens_hsa040660.55293383
111Glutathione metabolism_Homo sapiens_hsa004800.54545432
112Renal cell carcinoma_Homo sapiens_hsa052110.54212432
1132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.53519353
114Apoptosis_Homo sapiens_hsa042100.52926384
115Vibrio cholerae infection_Homo sapiens_hsa051100.52099753
116Prion diseases_Homo sapiens_hsa050200.52011240
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50799164
118Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.50255123
119Pentose and glucuronate interconversions_Homo sapiens_hsa000400.49876486
120Pyrimidine metabolism_Homo sapiens_hsa002400.48099198
121Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.47319578
122Salmonella infection_Homo sapiens_hsa051320.46830026
123AMPK signaling pathway_Homo sapiens_hsa041520.46814363
124Homologous recombination_Homo sapiens_hsa034400.46753711
125Folate biosynthesis_Homo sapiens_hsa007900.45389824
126Herpes simplex infection_Homo sapiens_hsa051680.44567095
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43838127
128Pentose phosphate pathway_Homo sapiens_hsa000300.43535952
129Carbon metabolism_Homo sapiens_hsa012000.41511560
130Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38904953
131RNA polymerase_Homo sapiens_hsa030200.34247433
132Sulfur metabolism_Homo sapiens_hsa009200.32797813
133Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.30990593
134Ras signaling pathway_Homo sapiens_hsa040140.29488315

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