RALGPS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)5.99058846
2cardiac ventricle formation (GO:0003211)5.57351860
3regulation of protein glycosylation (GO:0060049)5.23087707
4B cell proliferation (GO:0042100)5.16404419
5cardiac chamber formation (GO:0003207)5.08649200
6secondary heart field specification (GO:0003139)5.04379042
7heart field specification (GO:0003128)5.04379042
8phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)4.82319070
9piRNA metabolic process (GO:0034587)4.79567711
10nucleosome disassembly (GO:0006337)4.75701719
11protein-DNA complex disassembly (GO:0032986)4.75701719
12negative regulation of histone methylation (GO:0031061)4.73476803
13acrosome assembly (GO:0001675)4.51276072
14DNA methylation involved in gamete generation (GO:0043046)4.41755239
15histone H3-K9 modification (GO:0061647)4.16696899
16male meiosis (GO:0007140)4.06453020
17microtubule depolymerization (GO:0007019)4.02632260
18mitotic sister chromatid cohesion (GO:0007064)3.88256682
19epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.87778403
20regulation of histone H3-K9 methylation (GO:0051570)3.85750902
21regulation of B cell receptor signaling pathway (GO:0050855)3.85466880
22epithelial cilium movement (GO:0003351)3.79795489
23specification of organ identity (GO:0010092)3.75379981
24axonemal dynein complex assembly (GO:0070286)3.73789394
25cilium movement (GO:0003341)3.71700870
26sperm motility (GO:0030317)3.67992935
27cytoplasmic mRNA processing body assembly (GO:0033962)3.63429507
28peptidyl-lysine trimethylation (GO:0018023)3.62705028
29nuclear pore complex assembly (GO:0051292)3.43783549
30regulation of Rac protein signal transduction (GO:0035020)3.34802518
31positive regulation of DNA-templated transcription, initiation (GO:2000144)3.33218575
32negative regulation of osteoblast proliferation (GO:0033689)3.27968900
33embryonic process involved in female pregnancy (GO:0060136)3.27488917
34sperm-egg recognition (GO:0035036)3.26331663
35multicellular organism reproduction (GO:0032504)3.25641784
36histone lysine demethylation (GO:0070076)3.18621942
37negative regulation of fibroblast apoptotic process (GO:2000270)3.17683404
38fusion of sperm to egg plasma membrane (GO:0007342)3.17663934
39DNA methylation (GO:0006306)3.16938390
40DNA alkylation (GO:0006305)3.16938390
41B cell receptor signaling pathway (GO:0050853)3.14008647
42regulation of fibroblast apoptotic process (GO:2000269)3.13670625
43synaptonemal complex organization (GO:0070193)3.13545228
44paraxial mesoderm development (GO:0048339)3.12916203
45regulation of meiosis I (GO:0060631)3.12067890
46positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)3.10767142
47positive regulation of cell cycle checkpoint (GO:1901978)3.10662330
48synaptonemal complex assembly (GO:0007130)3.09350960
49negative regulation of DNA repair (GO:0045738)3.07716713
50regulation of RNA export from nucleus (GO:0046831)3.06563892
51sister chromatid segregation (GO:0000819)3.06477462
52gonadal mesoderm development (GO:0007506)3.04923890
53regulation of gene silencing by RNA (GO:0060966)3.04903522
54regulation of posttranscriptional gene silencing (GO:0060147)3.04903522
55regulation of gene silencing by miRNA (GO:0060964)3.04903522
56monoubiquitinated protein deubiquitination (GO:0035520)3.03874965
57sister chromatid cohesion (GO:0007062)3.02385770
58production of molecular mediator involved in inflammatory response (GO:0002532)3.00147530
59cell-cell recognition (GO:0009988)2.99181784
60histone H2A acetylation (GO:0043968)2.98127523
61gene silencing by RNA (GO:0031047)2.97996455
62DNA topological change (GO:0006265)2.97873451
63phospholipid translocation (GO:0045332)2.95598696
64lipid translocation (GO:0034204)2.95598696
65kinetochore organization (GO:0051383)2.95138806
66negative regulation of histone modification (GO:0031057)2.94468093
67binding of sperm to zona pellucida (GO:0007339)2.94332562
68motile cilium assembly (GO:0044458)2.93835739
69regulation of protein heterodimerization activity (GO:0043497)2.92609071
70nuclear pore organization (GO:0006999)2.92439462
71regulation of gene expression by genetic imprinting (GO:0006349)2.90327803
72regulation of B cell differentiation (GO:0045577)2.90200578
73spermatid development (GO:0007286)2.89836904
74peptidyl-arginine methylation (GO:0018216)2.88965932
75peptidyl-arginine N-methylation (GO:0035246)2.88965932
76positive regulation of neuroblast proliferation (GO:0002052)2.88436430
77replicative senescence (GO:0090399)2.88359732
78intra-S DNA damage checkpoint (GO:0031573)2.87318140
79regulation of glycoprotein biosynthetic process (GO:0010559)2.86541491
80histone H3-K9 methylation (GO:0051567)2.86446911
81regulation of histone methylation (GO:0031060)2.83923753
82histone mRNA catabolic process (GO:0071044)2.83748313
83protein localization to chromosome, centromeric region (GO:0071459)2.83631656
84histone demethylation (GO:0016577)2.83539142
85histone H4-K12 acetylation (GO:0043983)2.80038044
86spermatid nucleus differentiation (GO:0007289)2.80035650
87male meiosis I (GO:0007141)2.79855823
88meiotic nuclear division (GO:0007126)2.79744066
89resolution of meiotic recombination intermediates (GO:0000712)2.78592394
90histone H3-K36 demethylation (GO:0070544)2.77937533
91mitotic chromosome condensation (GO:0007076)2.76513189
92regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.76355843
93regulation of DNA-templated transcription, initiation (GO:2000142)2.75557696
94embryonic camera-type eye morphogenesis (GO:0048596)2.75467236
95peptidyl-arginine omega-N-methylation (GO:0035247)2.73780311
96negative regulation of chromatin modification (GO:1903309)2.73420237
97regulation of histone H3-K27 methylation (GO:0061085)2.73311207
98regulation of DNA damage checkpoint (GO:2000001)2.73077213
99mRNA splice site selection (GO:0006376)2.72731419
100negative regulation of T-helper cell differentiation (GO:0045623)2.72083465
101negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.72083465
102ventricular system development (GO:0021591)2.71891439
103peptidyl-lysine methylation (GO:0018022)2.71799821
104glomerulus development (GO:0032835)2.70182820
105DNA packaging (GO:0006323)2.69319885
106gland morphogenesis (GO:0022612)2.67591840
107positive regulation of developmental pigmentation (GO:0048087)2.67525546
108meiosis I (GO:0007127)2.66011029
109histone H3-K4 trimethylation (GO:0080182)2.65774361
110N-terminal protein amino acid acetylation (GO:0006474)2.65615125
111chromosome organization involved in meiosis (GO:0070192)2.65094949
112DNA methylation or demethylation (GO:0044728)2.63752799
113hepatocyte apoptotic process (GO:0097284)2.63737818
114meiotic chromosome segregation (GO:0045132)2.63587550
115mitotic sister chromatid segregation (GO:0000070)2.63242731
116meiotic cell cycle (GO:0051321)2.61302664
117kinetochore assembly (GO:0051382)2.61240638
118cellular response to virus (GO:0098586)2.61153490
119neuronal stem cell maintenance (GO:0097150)2.60106620
120dosage compensation (GO:0007549)2.59786668
121negative regulation of B cell proliferation (GO:0030889)2.57666356
122lateral sprouting from an epithelium (GO:0060601)2.57541677
123regulation of establishment of cell polarity (GO:2000114)2.56835686
124protein demethylation (GO:0006482)2.56553662
125protein dealkylation (GO:0008214)2.56553662
126genetic imprinting (GO:0071514)2.56158450
127acrosome reaction (GO:0007340)2.55456049
128negative regulation of axon guidance (GO:1902668)2.55355544
129chromosome condensation (GO:0030261)2.54080555
130regulation of nucleobase-containing compound transport (GO:0032239)2.51049204
131establishment of nucleus localization (GO:0040023)2.50957095
132neuron projection extension involved in neuron projection guidance (GO:1902284)2.50865753
133axon extension involved in axon guidance (GO:0048846)2.50865753
134V(D)J recombination (GO:0033151)2.50259391
135histone H4-K16 acetylation (GO:0043984)2.49080389
136plasma membrane fusion (GO:0045026)2.47754890
137positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.46772010
138positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.46772010
139positive regulation of mitotic sister chromatid separation (GO:1901970)2.46772010
140nucleosome organization (GO:0034728)2.46623010
141regulation of centriole replication (GO:0046599)2.46436933
142protein localization to chromosome (GO:0034502)2.46168750
143B cell activation (GO:0042113)2.45787483
144histone mRNA metabolic process (GO:0008334)2.45320404
145translesion synthesis (GO:0019985)2.44866038
146pore complex assembly (GO:0046931)2.44756789
147establishment of tissue polarity (GO:0007164)2.44501867
148establishment of planar polarity (GO:0001736)2.44501867
149pre-miRNA processing (GO:0031054)2.43892090
150positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.43392331
151regulation of sister chromatid cohesion (GO:0007063)2.42920320
152single strand break repair (GO:0000012)2.42475220
153pericardium development (GO:0060039)2.39876539
154regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.39748878
155histone H3-K9 demethylation (GO:0033169)2.39738704
156protein localization to kinetochore (GO:0034501)2.38821318
157positive regulation of gene expression, epigenetic (GO:0045815)2.37988876
158response to UV-B (GO:0010224)2.36799753
159mature B cell differentiation (GO:0002335)2.36074440
160microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.33222585
161histone H3 deacetylation (GO:0070932)2.32537204
162regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.32359298
163regulation of mitotic spindle checkpoint (GO:1903504)2.32359298
164B cell homeostasis (GO:0001782)2.31340997
165negative regulation of alpha-beta T cell differentiation (GO:0046639)2.30559410
166ear development (GO:0043583)2.30355881
167somatic stem cell division (GO:0048103)2.29988859
168lymphocyte proliferation (GO:0046651)2.28958245
169positive regulation of mRNA 3-end processing (GO:0031442)2.26938082
170sequestering of extracellular ligand from receptor (GO:0035581)2.25825713
171activation of JUN kinase activity (GO:0007257)2.25765277
172activation of Rac GTPase activity (GO:0032863)2.25400204
173positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.25307136
174Golgi to endosome transport (GO:0006895)2.24308304
175negative regulation of anoikis (GO:2000811)2.23923831
176regulation of pigment cell differentiation (GO:0050932)2.23259027
177regulation of interferon-beta biosynthetic process (GO:0045357)2.21456383
178regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.21405091
179embryonic body morphogenesis (GO:0010172)2.21346047

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.73051512
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.67164556
3* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.31333244
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.61027497
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.60522264
6RBPJ_22232070_ChIP-Seq_NCS_Mouse3.55080546
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.68582166
8E2F7_22180533_ChIP-Seq_HELA_Human2.59144597
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.45052091
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.39596853
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.37502636
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.21104767
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.16431609
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.15113763
15IGF1R_20145208_ChIP-Seq_DFB_Human2.14661249
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.05809320
17WDR5_24793694_ChIP-Seq_LNCAP_Human1.97843251
18NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.97791425
19RNF2_27304074_Chip-Seq_NSC_Mouse1.95409983
20GBX2_23144817_ChIP-Seq_PC3_Human1.84237325
21TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82056556
22POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.82056556
23CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.79676148
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.74864853
25ZNF217_24962896_ChIP-Seq_MCF-7_Human1.74536205
26* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74102629
27* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.73585336
28ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73575198
29TAF15_26573619_Chip-Seq_HEK293_Human1.72169935
30KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.71636979
31FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.70859056
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65076630
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63759547
34* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.61052259
35FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.58588486
36FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.57628514
37* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.55356046
38FUS_26573619_Chip-Seq_HEK293_Human1.53193261
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.52427797
40NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.50951236
41CDX2_19796622_ChIP-Seq_MESCs_Mouse1.49205038
42WT1_19549856_ChIP-ChIP_CCG9911_Human1.46933271
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.46108898
44CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.46073106
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45895729
46FOXO3_23340844_ChIP-Seq_DLD1_Human1.45746431
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45304978
48DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.43981403
49* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.40564943
50STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40494045
51FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.40457225
52GATA1_26923725_Chip-Seq_HPCs_Mouse1.38500395
53ELK4_26923725_Chip-Seq_MESODERM_Mouse1.38366568
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37605114
55IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.36119343
56P300_19829295_ChIP-Seq_ESCs_Human1.34665519
57* ESR1_20079471_ChIP-ChIP_T-47D_Human1.32871813
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.31774683
59CTBP1_25329375_ChIP-Seq_LNCAP_Human1.29526810
60* NANOG_18555785_Chip-Seq_ESCs_Mouse1.29347767
61EWS_26573619_Chip-Seq_HEK293_Human1.27104997
62E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.26627785
63* NFE2_27457419_Chip-Seq_LIVER_Mouse1.26081024
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.24021146
65* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.23344032
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21803405
67REST_21632747_ChIP-Seq_MESCs_Mouse1.21492066
68POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21051957
69* SMAD4_21799915_ChIP-Seq_A2780_Human1.20530175
70HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.19887470
71ZNF274_21170338_ChIP-Seq_K562_Hela1.18872117
72* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.18440752
73AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17791093
74CIITA_25753668_ChIP-Seq_RAJI_Human1.17553197
75SALL4_18804426_ChIP-ChIP_XEN_Mouse1.17455130
76EP300_21415370_ChIP-Seq_HL-1_Mouse1.15640121
77ER_23166858_ChIP-Seq_MCF-7_Human1.15492767
78* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15422770
79FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.14252865
80CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14236488
81RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.13698624
82RUNX_20019798_ChIP-Seq_JUKART_Human1.13294177
83* TCF4_23295773_ChIP-Seq_U87_Human1.13254761
84PKCTHETA_26484144_Chip-Seq_BREAST_Human1.13155341
85* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12527177
86PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.11943536
87SMAD_19615063_ChIP-ChIP_OVARY_Human1.11870686
88* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11382797
89MYC_22102868_ChIP-Seq_BL_Human1.10601297
90TP53_18474530_ChIP-ChIP_U2OS_Human1.10393789
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.08201295
92ARNT_22903824_ChIP-Seq_MCF-7_Human1.07991206
93BRD4_25478319_ChIP-Seq_HGPS_Human1.07548927
94* P53_22387025_ChIP-Seq_ESCs_Mouse1.07230670
95STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.06918216
96STAT3_23295773_ChIP-Seq_U87_Human1.06909357
97* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.06564747
98EZH2_27304074_Chip-Seq_ESCs_Mouse1.06221076
99ISL1_27105846_Chip-Seq_CPCs_Mouse1.06115714
100* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.06004858
101TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05788762
102* FOXA2_19822575_ChIP-Seq_HepG2_Human1.04871359
103* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.04570858
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03042484
105MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02801967
106STAT6_21828071_ChIP-Seq_BEAS2B_Human1.02791470
107NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02789026
108IRF8_27001747_Chip-Seq_BMDM_Mouse1.02570233
109TP63_23658742_ChIP-Seq_EP156T_Human1.02544185
110AR_21909140_ChIP-Seq_LNCAP_Human1.02232704
111RNF2_27304074_Chip-Seq_ESCs_Mouse1.01792753
112* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01151879
113TP53_16413492_ChIP-PET_HCT116_Human1.00967603
114* E2F1_18555785_Chip-Seq_ESCs_Mouse1.00507264
115PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00272590
116SOX9_26525672_Chip-Seq_HEART_Mouse0.99963525
117* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99636501
118TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99457976
119JARID2_20064375_ChIP-Seq_MESCs_Mouse0.99408109
120ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.99406815
121* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.98681624
122YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98046367
123* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97693732
124* CMYC_18555785_Chip-Seq_ESCs_Mouse0.97667480
125TCF4_18268006_ChIP-ChIP_LS174T_Human0.97597091
126* TBX3_20139965_ChIP-Seq_ESCs_Mouse0.97046820
127TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.96986069
128GF1B_26923725_Chip-Seq_HPCs_Mouse0.96276733
129* TBX3_20139965_ChIP-Seq_MESCs_Mouse0.95385294
130YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94159243
131* EZH2_27294783_Chip-Seq_NPCs_Mouse0.94057409
132* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93833836
133* CBP_20019798_ChIP-Seq_JUKART_Human0.93833836
134* TAL1_26923725_Chip-Seq_HPCs_Mouse0.93412216
135VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.93231064
136AHR_22903824_ChIP-Seq_MCF-7_Human0.93152297
137FOXA1_25552417_ChIP-Seq_VCAP_Human0.92706825
138FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.91777854
139KDM2B_26808549_Chip-Seq_REH_Human0.91764782
140* NMYC_18555785_Chip-Seq_ESCs_Mouse0.91741414
141AR_25329375_ChIP-Seq_VCAP_Human0.91632177
142SMAD3_21741376_ChIP-Seq_EPCs_Human0.91433216
143* OCT4_18555785_Chip-Seq_ESCs_Mouse0.91277784
144CDX2_22108803_ChIP-Seq_LS180_Human0.90911851
145PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90844630
146STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.90231801
147BCAT_22108803_ChIP-Seq_LS180_Human0.89833206
148* P300_18555785_Chip-Seq_ESCs_Mouse0.89789965
149* RUNX1_27457419_Chip-Seq_LIVER_Mouse0.89013472
150* STAT3_18555785_Chip-Seq_ESCs_Mouse0.87596176
151* CTCF_18555785_Chip-Seq_ESCs_Mouse0.87470238

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation3.33634895
2MP0002138_abnormal_hepatobiliary_system3.20655731
3MP0000569_abnormal_digit_pigmentation3.16285258
4MP0003787_abnormal_imprinting3.15390552
5MP0005410_abnormal_fertilization3.02879622
6MP0004272_abnormal_basement_membrane2.82980194
7MP0003890_abnormal_embryonic-extraembry2.82000040
8MP0010094_abnormal_chromosome_stability2.38637009
9MP0003121_genomic_imprinting2.34090736
10MP0006292_abnormal_olfactory_placode2.27292448
11MP0003183_abnormal_peptide_metabolism2.26390567
12MP0008057_abnormal_DNA_replication2.26098910
13MP0002102_abnormal_ear_morphology2.23600801
14MP0005248_abnormal_Harderian_gland2.21791656
15MP0001929_abnormal_gametogenesis2.19871217
16MP0003698_abnormal_male_reproductive2.17005379
17MP0005275_abnormal_skin_tensile2.16548383
18MP0003111_abnormal_nucleus_morphology2.00768572
19MP0002653_abnormal_ependyma_morphology1.95241166
20MP0009384_cardiac_valve_regurgitation1.95160186
21MP0005408_hypopigmentation1.90546257
22MP0002210_abnormal_sex_determination1.84614904
23MP0002009_preneoplasia1.83410408
24MP0008058_abnormal_DNA_repair1.80070483
25MP0003077_abnormal_cell_cycle1.73490668
26MP0005503_abnormal_tendon_morphology1.71518413
27MP0000778_abnormal_nervous_system1.68964336
28MP0000537_abnormal_urethra_morphology1.68846719
29MP0010678_abnormal_skin_adnexa1.67132325
30MP0000383_abnormal_hair_follicle1.65948697
31MP0000427_abnormal_hair_cycle1.63546620
32MP0003941_abnormal_skin_development1.61950446
33MP0000566_synostosis1.61161969
34MP0003315_abnormal_perineum_morphology1.60061796
35MP0008995_early_reproductive_senescence1.56687032
36MP0000631_abnormal_neuroendocrine_gland1.56286456
37MP0010352_gastrointestinal_tract_polyps1.56218989
38MP0002697_abnormal_eye_size1.55933603
39MP0002928_abnormal_bile_duct1.54129141
40MP0003091_abnormal_cell_migration1.54116363
41MP0002092_abnormal_eye_morphology1.53571051
42MP0003938_abnormal_ear_development1.51821495
43MP0003693_abnormal_embryo_hatching1.51800423
44MP0001800_abnormal_humoral_immune1.47904092
45MP0001145_abnormal_male_reproductive1.46053140
46MP0001968_abnormal_touch/_nociception1.44542175
47MP0000371_diluted_coat_color1.43813326
48MP0003123_paternal_imprinting1.42494049
49MP0003122_maternal_imprinting1.40495787
50MP0008789_abnormal_olfactory_epithelium1.39736765
51MP0000653_abnormal_sex_gland1.38636549
52MP0008438_abnormal_cutaneous_collagen1.37882326
53MP0010234_abnormal_vibrissa_follicle1.36845414
54MP0002161_abnormal_fertility/fecundity1.33777890
55MP0005499_abnormal_olfactory_system1.33357259
56MP0005394_taste/olfaction_phenotype1.33357259
57MP0005423_abnormal_somatic_nervous1.32752934
58MP0000428_abnormal_craniofacial_morphol1.31230162
59MP0004264_abnormal_extraembryonic_tissu1.30717429
60MP0003861_abnormal_nervous_system1.29989336
61MP0000767_abnormal_smooth_muscle1.29749838
62MP0005646_abnormal_pituitary_gland1.29220836
63MP0004885_abnormal_endolymph1.28573390
64MP0003705_abnormal_hypodermis_morpholog1.28465324
65MP0003252_abnormal_bile_duct1.26648035
66MP0008007_abnormal_cellular_replicative1.26082269
67MP0004134_abnormal_chest_morphology1.25035906
68MP0002557_abnormal_social/conspecific_i1.20801063
69MP0002736_abnormal_nociception_after1.20608540
70MP0003763_abnormal_thymus_physiology1.19945105
71MP0002160_abnormal_reproductive_system1.19719940
72MP0004197_abnormal_fetal_growth/weight/1.15273535
73MP0002234_abnormal_pharynx_morphology1.12330980
74MP0003937_abnormal_limbs/digits/tail_de1.10912440
75MP0006072_abnormal_retinal_apoptosis1.09862726
76MP0003119_abnormal_digestive_system1.09329359
77MP0002063_abnormal_learning/memory/cond1.08425427
78MP0002572_abnormal_emotion/affect_behav1.06914229
79MP0002084_abnormal_developmental_patter1.05715723
80MP0001348_abnormal_lacrimal_gland1.04913547
81MP0004883_abnormal_blood_vessel1.04792151
82MP0001293_anophthalmia1.03144368
83MP0004808_abnormal_hematopoietic_stem1.02492969
84MP0001984_abnormal_olfaction1.01200697
85MP0001188_hyperpigmentation1.01107187
86MP0001186_pigmentation_phenotype1.01078749
87MP0001286_abnormal_eye_development1.00536397
88MP0002086_abnormal_extraembryonic_tissu0.99701550
89MP0005257_abnormal_intraocular_pressure0.99454620
90MP0001666_abnormal_nutrient_absorption0.99433425
91MP0002735_abnormal_chemical_nociception0.99414428
92MP0005187_abnormal_penis_morphology0.99209023
93MP0003942_abnormal_urinary_system0.99145084
94MP0002095_abnormal_skin_pigmentation0.97153479
95MP0000432_abnormal_head_morphology0.97139149
96MP0003984_embryonic_growth_retardation0.97120514
97MP0005387_immune_system_phenotype0.96922672
98MP0001790_abnormal_immune_system0.96922672
99MP0005075_abnormal_melanosome_morpholog0.96854377
100MP0003868_abnormal_feces_composition0.96755742
101MP0003567_abnormal_fetal_cardiomyocyte0.96628590
102MP0002184_abnormal_innervation0.96361424
103MP0003221_abnormal_cardiomyocyte_apopto0.95802044
104MP0010030_abnormal_orbit_morphology0.95636499
105MP0001119_abnormal_female_reproductive0.95531127
106MP0005389_reproductive_system_phenotype0.95447916
107MP0003635_abnormal_synaptic_transmissio0.94317012
108MP0002751_abnormal_autonomic_nervous0.94295694
109MP0002152_abnormal_brain_morphology0.93913000
110MP0002088_abnormal_embryonic_growth/wei0.93540674
111MP0000689_abnormal_spleen_morphology0.93481166
112MP0006276_abnormal_autonomic_nervous0.93334236
113MP0002085_abnormal_embryonic_tissue0.93126866
114MP0006054_spinal_hemorrhage0.92735808
115MP0003935_abnormal_craniofacial_develop0.92474766
116MP0000534_abnormal_ureter_morphology0.92377142
117MP0002398_abnormal_bone_marrow0.92080427
118MP0004957_abnormal_blastocyst_morpholog0.91626532
119MP0000350_abnormal_cell_proliferation0.91561224
120MP0008961_abnormal_basal_metabolism0.91364543
121MP0009053_abnormal_anal_canal0.90041847
122MP0002067_abnormal_sensory_capabilities0.89389879
123MP0001986_abnormal_taste_sensitivity0.88993615
124MP0000026_abnormal_inner_ear0.88822439
125MP0001299_abnormal_eye_distance/0.88802114
126MP0003718_maternal_effect0.88785331
127MP0001919_abnormal_reproductive_system0.88527710
128MP0003385_abnormal_body_wall0.88252046
129MP0005076_abnormal_cell_differentiation0.88040343
130MP0008932_abnormal_embryonic_tissue0.87939521
131MP0002932_abnormal_joint_morphology0.87757575
132MP0002938_white_spotting0.87416914
133MP0008260_abnormal_autophagy0.87241390
134MP0004381_abnormal_hair_follicle0.86358238
135MP0005174_abnormal_tail_pigmentation0.86253395
136MP0001873_stomach_inflammation0.85599923
137MP0009703_decreased_birth_body0.85196445
138MP0001697_abnormal_embryo_size0.84869824
139MP0000377_abnormal_hair_follicle0.84796513
140MP0002282_abnormal_trachea_morphology0.84687066
141MP0005621_abnormal_cell_physiology0.84039761
142MP0002166_altered_tumor_susceptibility0.83949447
143MP0001915_intracranial_hemorrhage0.83032886
144MP0005551_abnormal_eye_electrophysiolog0.82963376
145MP0003115_abnormal_respiratory_system0.82891221
146MP0000703_abnormal_thymus_morphology0.82421102
147MP0001835_abnormal_antigen_presentation0.82143917
148MP0004133_heterotaxia0.81130679
149MP0001958_emphysema0.80680913
150MP0000716_abnormal_immune_system0.80471297
151MP0000015_abnormal_ear_pigmentation0.80404040
152MP0003786_premature_aging0.80244280
153MP0003755_abnormal_palate_morphology0.80083174
154MP0000762_abnormal_tongue_morphology0.79118545
155MP0002233_abnormal_nose_morphology0.78920215
156MP0002452_abnormal_antigen_presenting0.78599428
157MP0001486_abnormal_startle_reflex0.78573165
158MP0009745_abnormal_behavioral_response0.77913286
159MP0002877_abnormal_melanocyte_morpholog0.77806222
160MP0005380_embryogenesis_phenotype0.77608599
161MP0001672_abnormal_embryogenesis/_devel0.77608599
162MP0002420_abnormal_adaptive_immunity0.77359639
163MP0001730_embryonic_growth_arrest0.76972092
164MP0005501_abnormal_skin_physiology0.76559777
165MP0003943_abnormal_hepatobiliary_system0.75047716

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.71945685
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.35699971
3Absent/shortened dynein arms (HP:0200106)4.35699971
4Agammaglobulinemia (HP:0004432)4.08875594
5Recurrent sinusitis (HP:0011108)3.87728935
6Abnormal respiratory motile cilium physiology (HP:0012261)3.72081953
7Calf muscle hypertrophy (HP:0008981)3.52084505
8Abnormality of the intervertebral disk (HP:0005108)3.30207455
9Abnormal ciliary motility (HP:0012262)3.27615754
10Aqueductal stenosis (HP:0002410)3.25103706
11Abnormal respiratory epithelium morphology (HP:0012253)3.22203995
12Abnormal respiratory motile cilium morphology (HP:0005938)3.22203995
13Rhinitis (HP:0012384)3.05806281
14Type II lissencephaly (HP:0007260)2.99243756
15Emphysema (HP:0002097)2.90678393
16Muscle hypertrophy of the lower extremities (HP:0008968)2.81064787
17Chromosomal breakage induced by crosslinking agents (HP:0003221)2.75791850
18Recurrent bronchitis (HP:0002837)2.73797440
19Curly hair (HP:0002212)2.71909391
20Abnormality of the fingertips (HP:0001211)2.63356324
21Recurrent otitis media (HP:0000403)2.63149822
22Broad alveolar ridges (HP:0000187)2.58781605
23Gastrointestinal stroma tumor (HP:0100723)2.55416585
24Chromsome breakage (HP:0040012)2.54993706
25Cellulitis (HP:0100658)2.54893805
26Capillary hemangiomas (HP:0005306)2.52479423
27Missing ribs (HP:0000921)2.47572171
28Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.45070904
29Short 4th metacarpal (HP:0010044)2.45070904
30Nephronophthisis (HP:0000090)2.44642732
31Bronchitis (HP:0012387)2.40897787
32Broad palm (HP:0001169)2.38958068
33Syringomyelia (HP:0003396)2.36694354
34Spinal cord lesions (HP:0100561)2.36694354
35Pulmonic stenosis (HP:0001642)2.32279260
36Poikiloderma (HP:0001029)2.30593649
37Deep philtrum (HP:0002002)2.30498724
38Recurrent pneumonia (HP:0006532)2.29999981
39Bronchiectasis (HP:0002110)2.28567917
40Viral hepatitis (HP:0006562)2.27943814
41Volvulus (HP:0002580)2.26062628
42Midline defect of the nose (HP:0004122)2.23262204
43Ectopic kidney (HP:0000086)2.23215640
44Transitional cell carcinoma of the bladder (HP:0006740)2.21511823
45Chronic sinusitis (HP:0011109)2.21161703
46Clubbing of toes (HP:0100760)2.21078891
47Aplasia/Hypoplasia of the sternum (HP:0006714)2.19651410
48Thickened helices (HP:0000391)2.18400332
49Arterial tortuosity (HP:0005116)2.18000105
50Patellar aplasia (HP:0006443)2.16164536
51Papillary thyroid carcinoma (HP:0002895)2.15502554
52Vasculitis (HP:0002633)2.14490522
53Abnormality of DNA repair (HP:0003254)2.13889162
54Retinal dysplasia (HP:0007973)2.12930541
55Aplasia/Hypoplasia of the uvula (HP:0010293)2.12406970
5611 pairs of ribs (HP:0000878)2.07733339
57Meningocele (HP:0002435)2.07127879
58Overgrowth (HP:0001548)2.06924639
59Abnormality of the renal medulla (HP:0100957)2.06771514
60Aplasia/Hypoplasia of the patella (HP:0006498)2.05557803
61Infertility (HP:0000789)2.05271272
62Vascular tortuosity (HP:0004948)2.04531607
63Bladder neoplasm (HP:0009725)2.04293867
64Bladder carcinoma (HP:0002862)2.04293867
65Thyroiditis (HP:0100646)2.03932254
66Oligodactyly (hands) (HP:0001180)2.03553284
67Amyotrophic lateral sclerosis (HP:0007354)2.02354704
68Hypoplasia of the capital femoral epiphysis (HP:0003090)2.01550974
69Spinal rigidity (HP:0003306)1.98403838
70Asymmetry of the thorax (HP:0001555)1.98150686
71Deep palmar crease (HP:0006191)1.98023881
72Restrictive lung disease (HP:0002091)1.97771740
73Malignant gastrointestinal tract tumors (HP:0006749)1.97359901
74Gastrointestinal carcinoma (HP:0002672)1.97359901
75Inflammation of the large intestine (HP:0002037)1.96418144
76Nephroblastoma (Wilms tumor) (HP:0002667)1.95909697
77Neonatal hypoglycemia (HP:0001998)1.95681484
78Hyperventilation (HP:0002883)1.95459027
79Abnormal number of incisors (HP:0011064)1.95166474
80Septo-optic dysplasia (HP:0100842)1.93253719
81Narrow nasal bridge (HP:0000446)1.92926781
82Medulloblastoma (HP:0002885)1.92860849
83Lymphopenia (HP:0001888)1.92630724
84Chronic bronchitis (HP:0004469)1.91548308
85Facial hemangioma (HP:0000329)1.91542988
86Recurrent lower respiratory tract infections (HP:0002783)1.91258886
87Aortic aneurysm (HP:0004942)1.91161841
88Entropion (HP:0000621)1.90157823
89Meningitis (HP:0001287)1.89522377
90Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.89425838
91Panhypogammaglobulinemia (HP:0003139)1.88297799
92Tented upper lip vermilion (HP:0010804)1.86916337
93Slow-growing hair (HP:0002217)1.86417296
94Abnormality of hair growth rate (HP:0011363)1.86417296
95Colitis (HP:0002583)1.86178355
96Biliary tract neoplasm (HP:0100574)1.85718209
97Gastrointestinal inflammation (HP:0004386)1.84980771
98Thoracolumbar scoliosis (HP:0002944)1.83439149
99Osteomyelitis (HP:0002754)1.82930190
100Mitral valve prolapse (HP:0001634)1.82109563
101Severe visual impairment (HP:0001141)1.80121160
102Abnormality of cells of the lymphoid lineage (HP:0012140)1.80034485
103Oligodactyly (HP:0012165)1.79871229
104Cutis marmorata (HP:0000965)1.79574164
105Growth hormone deficiency (HP:0000824)1.78512022
106Tubulointerstitial nephritis (HP:0001970)1.78334481
107Basal cell carcinoma (HP:0002671)1.78220888
108Aortic dissection (HP:0002647)1.77693272
109Embryonal renal neoplasm (HP:0011794)1.77252224
110Thickened calvaria (HP:0002684)1.76686450
111Abnormality of the preputium (HP:0100587)1.76669279
112Cystic hygroma (HP:0000476)1.75050723
113Lymphoma (HP:0002665)1.74634821
114Abnormality of midbrain morphology (HP:0002418)1.74150325
115Molar tooth sign on MRI (HP:0002419)1.74150325
116Sparse lateral eyebrow (HP:0005338)1.74095298
117Uterine leiomyosarcoma (HP:0002891)1.73898026
118Leiomyosarcoma (HP:0100243)1.73898026
119Febrile seizures (HP:0002373)1.73480881
120Facial diplegia (HP:0001349)1.72886999
121Abnormality of chromosome segregation (HP:0002916)1.72619906
122Abnormality of the labia minora (HP:0012880)1.72179234
123Subacute progressive viral hepatitis (HP:0006572)1.72091438
124Abnormality of chromosome stability (HP:0003220)1.71652363
125Short philtrum (HP:0000322)1.71214728
126Heterotopia (HP:0002282)1.70937563
127Protruding tongue (HP:0010808)1.70923774
128Large earlobe (HP:0009748)1.70918132
129Impulsivity (HP:0100710)1.70664910
130Abnormal hair whorl (HP:0010721)1.70433040
131Highly arched eyebrow (HP:0002553)1.69336609
132Abnormality of the carotid arteries (HP:0005344)1.69284352
133Verrucae (HP:0200043)1.68657975
134Papilloma (HP:0012740)1.68657975
135Widely spaced teeth (HP:0000687)1.67233114
136Rhabdomyosarcoma (HP:0002859)1.66912073
137Epiphyseal dysplasia (HP:0002656)1.66260559
138Narrow palate (HP:0000189)1.66218294
139Meckel diverticulum (HP:0002245)1.66053832
140Diastasis recti (HP:0001540)1.65671526
141Pendular nystagmus (HP:0012043)1.65509130
142Medial flaring of the eyebrow (HP:0010747)1.65316693
143Vertebral arch anomaly (HP:0008438)1.65034000
144Abnormality of the lower motor neuron (HP:0002366)1.64807329
145Wide intermamillary distance (HP:0006610)1.64233378
146Abnormality of B cell number (HP:0010975)1.64221626
147B lymphocytopenia (HP:0010976)1.64221626
148Myelomeningocele (HP:0002475)1.62870694
149Increased nuchal translucency (HP:0010880)1.62433888
150Chronic hepatic failure (HP:0100626)1.61871148
151Abnormality of incisor morphology (HP:0011063)1.61869394
152Hepatoblastoma (HP:0002884)1.61553490
153Truncal obesity (HP:0001956)1.60767314
154Leukopenia (HP:0001882)1.60447692
155Abnormality of the ileum (HP:0001549)1.60376976
156Narrow forehead (HP:0000341)1.60090975
157Spina bifida occulta (HP:0003298)1.59917845
158Abnormal ventriculo-arterial connection (HP:0011563)1.59165088
159Transposition of the great arteries (HP:0001669)1.59165088
160Abnormal connection of the cardiac segments (HP:0011545)1.59165088
161Obsessive-compulsive behavior (HP:0000722)1.59015582
162Embryonal neoplasm (HP:0002898)1.58982689
163Anal stenosis (HP:0002025)1.57942256
164Postaxial foot polydactyly (HP:0001830)1.57934357
165Lip pit (HP:0100267)1.57870733
166Renovascular hypertension (HP:0100817)1.57527663
167Abnormality of the incisor (HP:0000676)1.56973036
168Small epiphyses (HP:0010585)1.56903221
169T lymphocytopenia (HP:0005403)1.56857751
170Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.56710946
171Absent frontal sinuses (HP:0002688)1.56071768
172Recurrent viral infections (HP:0004429)1.55667733
173Partial agenesis of the corpus callosum (HP:0001338)1.54346226
174Neonatal short-limb short stature (HP:0008921)1.53396084

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK195.30789910
2BLK3.29633831
3SIK32.41521071
4IRAK42.35418439
5MARK12.35098580
6PNCK2.28550929
7CDC72.20646543
8CASK2.17202447
9MAP4K12.16338720
10BRD42.15731846
11SRPK12.11715734
12CDK122.07088449
13PDK32.03765119
14PDK42.03765119
15MAPK132.01453103
16LATS11.99591427
17TAF11.99263051
18MELK1.96828295
19MAP3K101.90144932
20NEK21.87818465
21NEK91.70843330
22KSR11.69512942
23SIK21.69074743
24ACVR1B1.69027690
25CHEK21.68677254
26MKNK21.67316775
27CCNB11.66449235
28SGK21.66374494
29WNK11.65431729
30MAP3K41.61403503
31MAP2K71.59842860
32NTRK21.57924306
33GRK61.53922601
34CDC42BPA1.50274574
35DYRK31.42391302
36BMPR1B1.31610534
37STK31.29109809
38ERN11.28030357
39ERBB31.25426668
40TEC1.25247964
41YES11.23984380
42MARK21.20300890
43CHEK11.19492452
44NLK1.16898489
45TTK1.16343623
46ATR1.13293189
47PDGFRA1.13223728
48MKNK11.13148739
49SGK31.12864967
50PIK3CG1.10350541
51BRSK21.10305157
52SIK11.08360675
53CDK91.07108806
54FGFR31.04180444
55PLK31.03143201
56STK38L1.02653248
57SYK1.02456002
58FGFR21.00262894
59GRK10.99254602
60FGFR40.98841908
61BRSK10.97327650
62MAP3K120.97326372
63RPS6KA40.95855039
64CAMK1G0.94682028
65RIPK40.94139546
66EPHB20.93026968
67DYRK1A0.92625805
68CDK60.91596234
69NTRK30.91125660
70STK240.90296423
71CSF1R0.89469993
72ICK0.89285353
73DYRK20.87634945
74BCR0.86656268
75MAP3K20.86256730
76PLK10.84717588
77FGFR10.84704198
78DYRK1B0.83697171
79CDK30.82163478
80PLK40.81002257
81MAP3K130.79855052
82TGFBR10.79218605
83PRPF4B0.77994064
84STK100.77044509
85ATM0.77008118
86TRIM280.75958455
87PLK20.74076775
88PKN20.73718036
89ITK0.72192780
90LATS20.72149209
91BMPR20.69377004
92UHMK10.68263565
93SGK4940.67714252
94SGK2230.67714252
95FRK0.67114150
96RPS6KB10.66920496
97BRAF0.66114701
98TYK20.63923512
99ALK0.63873539
100AURKB0.62874333
101CDK20.62067690
102PINK10.61957584
103PDK20.60495823
104CSNK1A1L0.59508604
105CDK10.59306532
106BTK0.59061606
107CDK80.58578922
108LYN0.55965205
109VRK10.55308848
110HCK0.55145753
111PASK0.53659487
112MST40.53261554
113IKBKE0.52765238
114ZAK0.51854375
115BUB10.51748567
116MAP3K70.51624232
117MARK30.51113219
118EEF2K0.50384972
119NUAK10.49401836
120MAP3K90.49203656
121EIF2AK20.48527915
122IRAK20.48232547
123SGK10.48190590
124CHUK0.47425229
125LRRK20.47182903
126TRIB30.46489992
127AKT30.45239926
128CSNK1D0.45091379
129IRAK10.45021702
130JAK30.44953967
131STK380.44515201
132MATK0.44184177
133JAK10.43805867
134CSNK1G20.42544056
135GSK3B0.42162998
136KSR20.41730418
137CDK40.41637487
138MAPK110.40745526
139PDGFRB0.40159892
140MAPK140.38102249
141MTOR0.35857638
142EGFR0.33631918
143ABL10.32611071
144MAPK70.31951571
145MET0.31395662
146PRKCZ0.30204800
147STK390.29920109

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.76746585
2Fanconi anemia pathway_Homo sapiens_hsa034602.70348560
3Primary immunodeficiency_Homo sapiens_hsa053402.56831568
4Cell cycle_Homo sapiens_hsa041102.23528362
5Dorso-ventral axis formation_Homo sapiens_hsa043202.08618974
6mRNA surveillance pathway_Homo sapiens_hsa030152.06811498
7Phototransduction_Homo sapiens_hsa047441.87534075
8Oocyte meiosis_Homo sapiens_hsa041141.77919347
9Thyroid cancer_Homo sapiens_hsa052161.75555786
10Staphylococcus aureus infection_Homo sapiens_hsa051501.72970292
11Asthma_Homo sapiens_hsa053101.70642700
12Basal transcription factors_Homo sapiens_hsa030221.70310498
13Spliceosome_Homo sapiens_hsa030401.70252768
14Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.70099578
15Nicotine addiction_Homo sapiens_hsa050331.69908865
16Basal cell carcinoma_Homo sapiens_hsa052171.68708073
17Base excision repair_Homo sapiens_hsa034101.57529828
18Autoimmune thyroid disease_Homo sapiens_hsa053201.49855148
19Long-term potentiation_Homo sapiens_hsa047201.48211962
20Hedgehog signaling pathway_Homo sapiens_hsa043401.47736771
21Leishmaniasis_Homo sapiens_hsa051401.47072099
22Non-homologous end-joining_Homo sapiens_hsa034501.45948945
23Homologous recombination_Homo sapiens_hsa034401.43556543
24Allograft rejection_Homo sapiens_hsa053301.40835671
25RNA transport_Homo sapiens_hsa030131.37149804
26Olfactory transduction_Homo sapiens_hsa047401.36749931
27Systemic lupus erythematosus_Homo sapiens_hsa053221.35205632
28Renal cell carcinoma_Homo sapiens_hsa052111.33516581
29RNA degradation_Homo sapiens_hsa030181.33241394
30Wnt signaling pathway_Homo sapiens_hsa043101.33137821
31Graft-versus-host disease_Homo sapiens_hsa053321.33104381
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.30607691
33Colorectal cancer_Homo sapiens_hsa052101.28749083
34Alcoholism_Homo sapiens_hsa050341.27895240
35Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23644038
36Notch signaling pathway_Homo sapiens_hsa043301.21235021
37Endometrial cancer_Homo sapiens_hsa052131.20729715
38Hematopoietic cell lineage_Homo sapiens_hsa046401.18652088
39Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.18295493
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.18196223
41Circadian entrainment_Homo sapiens_hsa047131.17766848
42Lysine degradation_Homo sapiens_hsa003101.17359656
43Epstein-Barr virus infection_Homo sapiens_hsa051691.17325709
44Toxoplasmosis_Homo sapiens_hsa051451.16644277
45Amphetamine addiction_Homo sapiens_hsa050311.16631319
46Viral myocarditis_Homo sapiens_hsa054161.13797461
47Non-small cell lung cancer_Homo sapiens_hsa052231.12591247
48Proteoglycans in cancer_Homo sapiens_hsa052051.12222459
49Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11352718
50Glutamatergic synapse_Homo sapiens_hsa047241.11314717
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11034734
52MicroRNAs in cancer_Homo sapiens_hsa052061.10358013
53Herpes simplex infection_Homo sapiens_hsa051681.10329083
54Mismatch repair_Homo sapiens_hsa034301.10019296
55Axon guidance_Homo sapiens_hsa043601.06310287
56Morphine addiction_Homo sapiens_hsa050321.04442246
57Dopaminergic synapse_Homo sapiens_hsa047281.02086528
58Thyroid hormone signaling pathway_Homo sapiens_hsa049191.01895175
59T cell receptor signaling pathway_Homo sapiens_hsa046601.01264110
60Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99936252
61Pentose phosphate pathway_Homo sapiens_hsa000300.99620903
62Taste transduction_Homo sapiens_hsa047420.99267872
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.96099408
64Melanoma_Homo sapiens_hsa052180.95007737
65Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.93592190
66GnRH signaling pathway_Homo sapiens_hsa049120.91697913
67Aldosterone synthesis and secretion_Homo sapiens_hsa049250.91621348
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.90794785
69DNA replication_Homo sapiens_hsa030300.90476482
70HTLV-I infection_Homo sapiens_hsa051660.90248272
71Renin secretion_Homo sapiens_hsa049240.90102361
72Estrogen signaling pathway_Homo sapiens_hsa049150.89536754
73Focal adhesion_Homo sapiens_hsa045100.88478395
74Viral carcinogenesis_Homo sapiens_hsa052030.88049855
75Glioma_Homo sapiens_hsa052140.87425011
76Choline metabolism in cancer_Homo sapiens_hsa052310.87029387
77Leukocyte transendothelial migration_Homo sapiens_hsa046700.85247394
78Prolactin signaling pathway_Homo sapiens_hsa049170.84841059
79Glucagon signaling pathway_Homo sapiens_hsa049220.84160863
80Hippo signaling pathway_Homo sapiens_hsa043900.84121511
81NF-kappa B signaling pathway_Homo sapiens_hsa040640.82582595
82Melanogenesis_Homo sapiens_hsa049160.81207145
83ErbB signaling pathway_Homo sapiens_hsa040120.80868336
84Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.78922713
85Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.78425081
86Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.78411232
87Acute myeloid leukemia_Homo sapiens_hsa052210.78345287
88Calcium signaling pathway_Homo sapiens_hsa040200.77761773
89Intestinal immune network for IgA production_Homo sapiens_hsa046720.76935449
90PI3K-Akt signaling pathway_Homo sapiens_hsa041510.76551460
91FoxO signaling pathway_Homo sapiens_hsa040680.75335055
92Long-term depression_Homo sapiens_hsa047300.74293391
93MAPK signaling pathway_Homo sapiens_hsa040100.74106722
94Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73730436
95Inositol phosphate metabolism_Homo sapiens_hsa005620.71179350
96Insulin secretion_Homo sapiens_hsa049110.70701788
97Type I diabetes mellitus_Homo sapiens_hsa049400.70592125
98Complement and coagulation cascades_Homo sapiens_hsa046100.70243714
99Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69662977
100Pancreatic cancer_Homo sapiens_hsa052120.68517632
101p53 signaling pathway_Homo sapiens_hsa041150.67429134
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67216224
103TGF-beta signaling pathway_Homo sapiens_hsa043500.66870508
104Neurotrophin signaling pathway_Homo sapiens_hsa047220.65896323
105Cholinergic synapse_Homo sapiens_hsa047250.65576763
106Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.64890342
107Hepatitis B_Homo sapiens_hsa051610.64773568
108cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63554374
109Hepatitis C_Homo sapiens_hsa051600.62446761
110Adherens junction_Homo sapiens_hsa045200.60735089
111Osteoclast differentiation_Homo sapiens_hsa043800.60634866
112Nucleotide excision repair_Homo sapiens_hsa034200.59690088
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.58623419
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58013036
115Oxytocin signaling pathway_Homo sapiens_hsa049210.57951540
116Pathways in cancer_Homo sapiens_hsa052000.57908285
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.57054641
118Prostate cancer_Homo sapiens_hsa052150.56695679
119Tuberculosis_Homo sapiens_hsa051520.56608350
120Chronic myeloid leukemia_Homo sapiens_hsa052200.56006667
121Serotonergic synapse_Homo sapiens_hsa047260.55990308
122Protein digestion and absorption_Homo sapiens_hsa049740.55836962
123Salivary secretion_Homo sapiens_hsa049700.55657639
124Platelet activation_Homo sapiens_hsa046110.55198036
125ECM-receptor interaction_Homo sapiens_hsa045120.54780735
126Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54728999
127Influenza A_Homo sapiens_hsa051640.54728024
128Gap junction_Homo sapiens_hsa045400.54004033
129mTOR signaling pathway_Homo sapiens_hsa041500.52892836
130N-Glycan biosynthesis_Homo sapiens_hsa005100.52796806
131Small cell lung cancer_Homo sapiens_hsa052220.52383180
132Antigen processing and presentation_Homo sapiens_hsa046120.50814628
133Chemokine signaling pathway_Homo sapiens_hsa040620.49865136
134Gastric acid secretion_Homo sapiens_hsa049710.49766848
135Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49755965
136Retinol metabolism_Homo sapiens_hsa008300.49377655
137Jak-STAT signaling pathway_Homo sapiens_hsa046300.48751756
138Tight junction_Homo sapiens_hsa045300.48330090
139Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45816352
140Rap1 signaling pathway_Homo sapiens_hsa040150.45702200

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