RANBP3L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1polyol transport (GO:0015791)8.90577698
2excretion (GO:0007588)7.63643945
3response to mercury ion (GO:0046689)7.60011117
4renal absorption (GO:0070293)7.19790690
5metanephric nephron tubule development (GO:0072234)6.46912634
6metanephric tubule development (GO:0072170)6.46912634
7adenine nucleotide transport (GO:0051503)6.27925714
8axon ensheathment in central nervous system (GO:0032291)6.13262110
9central nervous system myelination (GO:0022010)6.13262110
10lysine catabolic process (GO:0006554)6.11507291
11lysine metabolic process (GO:0006553)6.11507291
12metanephric nephron epithelium development (GO:0072243)6.01461514
13purine nucleotide transport (GO:0015865)5.77398829
14purine ribonucleotide transport (GO:0015868)5.66640323
15L-amino acid import (GO:0043092)5.55831695
16metanephric epithelium development (GO:0072207)5.51494205
17synaptic vesicle docking involved in exocytosis (GO:0016081)5.50377194
18drug transmembrane transport (GO:0006855)5.48913094
19collecting duct development (GO:0072044)5.31387219
20cysteine metabolic process (GO:0006534)5.22312999
21urate metabolic process (GO:0046415)5.18800552
22phosphate ion transport (GO:0006817)5.16999979
23one-carbon compound transport (GO:0019755)5.16681906
24membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.03665665
25drug transport (GO:0015893)4.92473992
26branched-chain amino acid metabolic process (GO:0009081)4.90591838
27branched-chain amino acid catabolic process (GO:0009083)4.85924816
28homocysteine metabolic process (GO:0050667)4.85894873
29synaptic vesicle maturation (GO:0016188)4.84248330
30valine metabolic process (GO:0006573)4.83607612
31aspartate family amino acid catabolic process (GO:0009068)4.81901137
32glutamate secretion (GO:0014047)4.76837849
33amino acid import (GO:0043090)4.74669606
34phosphate ion transmembrane transport (GO:0035435)4.61894281
35organic cation transport (GO:0015695)4.60180047
36cellular modified amino acid catabolic process (GO:0042219)4.55610996
37nephron tubule development (GO:0072080)4.45753784
38aminoglycoside antibiotic metabolic process (GO:0030647)4.44697240
39synaptic vesicle exocytosis (GO:0016079)4.41558384
40actin filament depolymerization (GO:0030042)4.38805916
41potassium ion homeostasis (GO:0055075)4.28669596
42erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.23244373
43L-phenylalanine catabolic process (GO:0006559)4.23244373
44potassium ion import (GO:0010107)4.21526607
452-oxoglutarate metabolic process (GO:0006103)4.19302136
46glyoxylate metabolic process (GO:0046487)4.18860892
47regulation of synaptic vesicle exocytosis (GO:2000300)4.18224354
48cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.18060845
49short-chain fatty acid metabolic process (GO:0046459)4.12786638
50erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.12655934
51L-phenylalanine metabolic process (GO:0006558)4.12655934
52gamma-aminobutyric acid transport (GO:0015812)4.10676627
53postsynaptic membrane organization (GO:0001941)4.09026673
54positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.05512089
55response to parathyroid hormone (GO:0071107)4.04673703
56neurotransmitter uptake (GO:0001504)3.98981125
57cerebellar granule cell differentiation (GO:0021707)3.98852344
58quaternary ammonium group transport (GO:0015697)3.98724777
59regulation of short-term neuronal synaptic plasticity (GO:0048172)3.94975134
60aromatic amino acid family catabolic process (GO:0009074)3.92318906
61neuronal action potential propagation (GO:0019227)3.91369704
62renal tubule development (GO:0061326)3.89154099
63neuron cell-cell adhesion (GO:0007158)3.86980852
64toxin transport (GO:1901998)3.82510664
65sodium ion export (GO:0071436)3.81116433
66cellular sodium ion homeostasis (GO:0006883)3.80282203
67presynaptic membrane assembly (GO:0097105)3.79640750
68tryptophan catabolic process (GO:0006569)3.78372719
69indole-containing compound catabolic process (GO:0042436)3.78372719
70indolalkylamine catabolic process (GO:0046218)3.78372719
71regulation of synaptic vesicle transport (GO:1902803)3.77926518
72cell volume homeostasis (GO:0006884)3.76499112
73response to water (GO:0009415)3.76455639
74neurotransmitter secretion (GO:0007269)3.73125324
75locomotory exploration behavior (GO:0035641)3.71284854
76nephron epithelium development (GO:0072009)3.67120077
77tricarboxylic acid metabolic process (GO:0072350)3.65299383
78regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.63124672
79glutamate metabolic process (GO:0006536)3.62237633
80regulation of neuronal synaptic plasticity (GO:0048168)3.57583116
81ionotropic glutamate receptor signaling pathway (GO:0035235)3.56900471
82presynaptic membrane organization (GO:0097090)3.54429654
83cellular ketone body metabolic process (GO:0046950)3.53921271
84biotin metabolic process (GO:0006768)3.53859499
85kynurenine metabolic process (GO:0070189)3.51570053
86tryptophan metabolic process (GO:0006568)3.50338660
87cell communication by electrical coupling (GO:0010644)3.47553262
88positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.44827248
89water transport (GO:0006833)3.42771984
90cellular potassium ion homeostasis (GO:0030007)3.40750978
91amino-acid betaine transport (GO:0015838)3.38538548
92carnitine transport (GO:0015879)3.38538548
93protein localization to synapse (GO:0035418)3.36418926
94exploration behavior (GO:0035640)3.36055595
95amino-acid betaine metabolic process (GO:0006577)3.35598808
96vocalization behavior (GO:0071625)3.34510998
97regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.31501582
98nonribosomal peptide biosynthetic process (GO:0019184)3.31393290
99nucleotide transport (GO:0006862)3.31369782
100cellular amino acid catabolic process (GO:0009063)3.28719941
101neurotransmitter-gated ion channel clustering (GO:0072578)3.28530000
102cardiovascular system development (GO:0072358)3.26335828
103proline metabolic process (GO:0006560)3.22562278
104positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.21902898
105cobalamin metabolic process (GO:0009235)3.21687533
106fatty acid beta-oxidation (GO:0006635)3.21068136
107regulation of long-term neuronal synaptic plasticity (GO:0048169)3.19537540
108gamma-aminobutyric acid signaling pathway (GO:0007214)3.18972112
109synaptic transmission, glutamatergic (GO:0035249)3.18495956
110regulation of synapse structural plasticity (GO:0051823)3.18133112
111sulfur amino acid catabolic process (GO:0000098)3.17910696
112drug catabolic process (GO:0042737)3.15995119
113cGMP-mediated signaling (GO:0019934)3.15892698
114neurotransmitter transport (GO:0006836)3.15789839
115vitamin D metabolic process (GO:0042359)3.13842897
116regulation of voltage-gated calcium channel activity (GO:1901385)3.13263897
117neuronal ion channel clustering (GO:0045161)3.11854439
118alpha-amino acid catabolic process (GO:1901606)3.10428136
119fluid transport (GO:0042044)3.09477318
120acidic amino acid transport (GO:0015800)3.08062638
121negative regulation of digestive system process (GO:0060457)3.05725885
122exocrine pancreas development (GO:0031017)3.05590232
123serine family amino acid biosynthetic process (GO:0009070)3.05565637
124innervation (GO:0060384)3.02001568
125nephron epithelium morphogenesis (GO:0072088)3.01950775
126nephron tubule morphogenesis (GO:0072078)3.01950775
127regulation of neurotransmitter secretion (GO:0046928)3.01660847
128transepithelial transport (GO:0070633)3.00784755
129digestion (GO:0007586)3.00747459
130C4-dicarboxylate transport (GO:0015740)3.00181371
131positive regulation of membrane potential (GO:0045838)2.99467205
132serine family amino acid metabolic process (GO:0009069)2.99160298
133regulation of glutamate receptor signaling pathway (GO:1900449)2.98562581
134ketone body metabolic process (GO:1902224)2.98295159
135regulation of excitatory postsynaptic membrane potential (GO:0060079)2.96802383
136regulation of neurotransmitter levels (GO:0001505)2.96147033
137fatty acid oxidation (GO:0019395)2.96082868
138intestinal cholesterol absorption (GO:0030299)2.95235763
139amine catabolic process (GO:0009310)2.95225450
140cellular biogenic amine catabolic process (GO:0042402)2.95225450
141lipid oxidation (GO:0034440)2.94858910
142regulation of neurotransmitter transport (GO:0051588)2.92725421
143renal system process (GO:0003014)2.92090736
144fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.92034243
145regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.91784414
146astrocyte development (GO:0014002)2.90371917
147regulation of cardiac muscle cell contraction (GO:0086004)2.90122072
148carboxylic acid catabolic process (GO:0046395)2.90075533
149organic acid catabolic process (GO:0016054)2.90075533
150auditory behavior (GO:0031223)2.89945663
151serine family amino acid catabolic process (GO:0009071)2.89397675
152carnitine metabolic process (GO:0009437)2.88118610
153negative regulation of neurotransmitter transport (GO:0051589)2.87432391
154dicarboxylic acid biosynthetic process (GO:0043650)2.87084910
155negative regulation of cytosolic calcium ion concentration (GO:0051481)2.86665723
156regulation of synaptic plasticity (GO:0048167)2.86485498
157exogenous drug catabolic process (GO:0042738)2.86161018
158neuromuscular process controlling balance (GO:0050885)2.86149098
159glutamate receptor signaling pathway (GO:0007215)2.85918686
160positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.85155653
161fatty acid catabolic process (GO:0009062)2.84940179
162detection of calcium ion (GO:0005513)2.84002100
163negative regulation of synaptic transmission, GABAergic (GO:0032229)2.82327460
164neuron-neuron synaptic transmission (GO:0007270)2.81375491
165sodium ion transport (GO:0006814)2.80458109
166regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.79927702
167positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.79440769
168regulation of ARF protein signal transduction (GO:0032012)2.78439367
169acetyl-CoA metabolic process (GO:0006084)2.78018566
170response to auditory stimulus (GO:0010996)2.76850288
171synaptic vesicle endocytosis (GO:0048488)2.76649390
172urinary tract smooth muscle contraction (GO:0014848)2.76296123
173L-glutamate transport (GO:0015813)2.75773902
174dicarboxylic acid catabolic process (GO:0043649)2.75615883
175glutathione biosynthetic process (GO:0006750)2.75520140
176regulation of postsynaptic membrane potential (GO:0060078)2.72903002
177membrane depolarization during action potential (GO:0086010)2.70589271
178cochlea development (GO:0090102)2.69785859
179regulation of synaptic transmission, glutamatergic (GO:0051966)2.69663676
180negative regulation of dendrite morphogenesis (GO:0050774)2.67893518
181regulation of sensory perception of pain (GO:0051930)2.66567575
182regulation of sensory perception (GO:0051931)2.66567575
183positive regulation of synapse maturation (GO:0090129)2.66401399
184positive regulation of dendritic spine development (GO:0060999)2.64292190
185myelination (GO:0042552)2.63997951
186cell communication involved in cardiac conduction (GO:0086065)2.61838960
187positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.60729797
188glomerular basement membrane development (GO:0032836)2.60705736
189long-term synaptic potentiation (GO:0060291)2.60309183
190import into cell (GO:0098657)2.60053705
191regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.57161423
192regulation of vesicle fusion (GO:0031338)2.56191932

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.86886647
2RXR_22158963_ChIP-Seq_LIVER_Mouse2.84695983
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.38781280
4LXR_22158963_ChIP-Seq_LIVER_Mouse2.33999327
5PPARA_22158963_ChIP-Seq_LIVER_Mouse2.28369561
6AR_21572438_ChIP-Seq_LNCaP_Human2.18304151
7GBX2_23144817_ChIP-Seq_PC3_Human2.17581774
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.16448749
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.15826479
10ESR2_21235772_ChIP-Seq_MCF-7_Human2.15117969
11REST_21632747_ChIP-Seq_MESCs_Mouse2.08234428
12PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.04499870
13ERG_21242973_ChIP-ChIP_JURKAT_Human2.02513355
14ESR1_21235772_ChIP-Seq_MCF-7_Human1.95890387
15NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83938770
16SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.79138753
17FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.76807629
18RARB_27405468_Chip-Seq_BRAIN_Mouse1.72649814
19SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.72033236
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.66199191
21RNF2_18974828_ChIP-Seq_MESCs_Mouse1.65545377
22EZH2_18974828_ChIP-Seq_MESCs_Mouse1.65545377
23SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64986949
24MTF2_20144788_ChIP-Seq_MESCs_Mouse1.64970819
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.62273744
26HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.58308316
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.55586271
28* PIAS1_25552417_ChIP-Seq_VCAP_Human1.54002650
29JARID2_20064375_ChIP-Seq_MESCs_Mouse1.52054309
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52037752
31EZH2_22144423_ChIP-Seq_EOC_Human1.51722603
32EGR1_23403033_ChIP-Seq_LIVER_Mouse1.51159464
33SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.50222920
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.49589305
35CDX2_20551321_ChIP-Seq_CACO-2_Human1.49390959
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47297025
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46100142
38SUZ12_27294783_Chip-Seq_ESCs_Mouse1.43207186
39SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.42471769
40OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40652702
41RARG_19884340_ChIP-ChIP_MEFs_Mouse1.40440238
42IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.39915382
43JARID2_20075857_ChIP-Seq_MESCs_Mouse1.39764896
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.39711779
45DROSHA_22980978_ChIP-Seq_HELA_Human1.39436002
46SMAD3_21741376_ChIP-Seq_HESCs_Human1.38517814
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.38045476
48BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36741645
49NR3C1_23031785_ChIP-Seq_PC12_Mouse1.35027441
50ZNF217_24962896_ChIP-Seq_MCF-7_Human1.34998404
51TRIM28_21343339_ChIP-Seq_HEK293_Human1.34138927
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.33555064
53RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.33364283
54PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.32641193
55TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31947971
56P300_19829295_ChIP-Seq_ESCs_Human1.30928356
57CTNNB1_20460455_ChIP-Seq_HCT116_Human1.30578559
58NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.29447231
59YAP1_20516196_ChIP-Seq_MESCs_Mouse1.28899726
60TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28274363
61IGF1R_20145208_ChIP-Seq_DFB_Human1.27935773
62FOXA2_19822575_ChIP-Seq_HepG2_Human1.26872705
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25866977
64EZH2_27294783_Chip-Seq_ESCs_Mouse1.23994458
65EP300_21415370_ChIP-Seq_HL-1_Mouse1.23250415
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.21798737
67ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.20785649
68STAT3_23295773_ChIP-Seq_U87_Human1.19542846
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.19352900
70SMAD4_21741376_ChIP-Seq_HESCs_Human1.18630067
71RXR_22108803_ChIP-Seq_LS180_Human1.18253453
72BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.17175540
73* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17002053
74CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16078153
75CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15938334
76TP53_16413492_ChIP-PET_HCT116_Human1.15302372
77LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14598699
78MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12289626
79TCF4_23295773_ChIP-Seq_U87_Human1.12206480
80EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12005676
81CDX2_19796622_ChIP-Seq_MESCs_Mouse1.11926986
82* GATA4_25053715_ChIP-Seq_YYC3_Human1.11240478
83GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.10506898
84IKZF1_21737484_ChIP-ChIP_HCT116_Human1.10455446
85RNF2_27304074_Chip-Seq_NSC_Mouse1.08405177
86SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.08232074
87TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08215627
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.07537919
89AHR_22903824_ChIP-Seq_MCF-7_Human1.07147478
90KDM2B_26808549_Chip-Seq_REH_Human1.05779826
91TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.05599538
92TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05025486
93PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.04071025
94MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03418340
95RNF2_27304074_Chip-Seq_ESCs_Mouse1.03394372
96AR_25329375_ChIP-Seq_VCAP_Human1.03157632
97* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03090355
98CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02688930
99ARNT_22903824_ChIP-Seq_MCF-7_Human1.02141343
100SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.01025469
101WT1_25993318_ChIP-Seq_PODOCYTE_Human0.99100914
102SOX9_26525672_Chip-Seq_HEART_Mouse0.97412639
103GATA1_26923725_Chip-Seq_HPCs_Mouse0.97010737
104UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96809944
105FOXO3_23340844_ChIP-Seq_DLD1_Human0.96532966
106CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.96529078
107* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.96396865
108* TP53_18474530_ChIP-ChIP_U2OS_Human0.96121155
109PPAR_26484153_Chip-Seq_NCI-H1993_Human0.95864023
110* P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95713086
111RING1B_27294783_Chip-Seq_NPCs_Mouse0.95699040
112SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94412212
113SOX2_27498859_Chip-Seq_STOMACH_Mouse0.94411015
114CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.93895171
115ZFP57_27257070_Chip-Seq_ESCs_Mouse0.93207205
116HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.92966227
117P53_22387025_ChIP-Seq_ESCs_Mouse0.92546019
118CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90527219
119SOX2_21211035_ChIP-Seq_LN229_Gbm0.90228915
120ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.88795641
121MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.88545100
122HNF4A_19822575_ChIP-Seq_HepG2_Human0.88252332
123SMAD4_21799915_ChIP-Seq_A2780_Human0.88222045
124SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87523359
125NRF2_20460467_ChIP-Seq_MEFs_Mouse0.86582269
126NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.86582269
127TAF15_26573619_Chip-Seq_HEK293_Human0.84941830
128TCF4_18268006_ChIP-ChIP_LS174T_Human0.84258186
129VDR_22108803_ChIP-Seq_LS180_Human0.84147840
130EZH2_27304074_Chip-Seq_ESCs_Mouse0.83999495
131BCAT_22108803_ChIP-Seq_LS180_Human0.80999957
132NR3C1_21868756_ChIP-Seq_MCF10A_Human0.80818966
133LXR_22292898_ChIP-Seq_THP-1_Human0.79433122
134TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.78805135
135AR_19668381_ChIP-Seq_PC3_Human0.78381647
136SOX2_20726797_ChIP-Seq_SW620_Human0.77956460
137PCGF2_27294783_Chip-Seq_NPCs_Mouse0.77504586
138ESET_19884257_ChIP-Seq_ESCs_Mouse0.76560240
139SMAD4_21741376_ChIP-Seq_EPCs_Human0.76320164
140RING1B_27294783_Chip-Seq_ESCs_Mouse0.75386295
141FOXM1_26456572_ChIP-Seq_MCF-7_Human0.75233873
142TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.75208410
143* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.74941181
144CBX2_27304074_Chip-Seq_ESCs_Mouse0.74678625

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004043_abnormal_pH_regulation8.11740013
2MP0003195_calcinosis6.38712265
3MP0005360_urolithiasis4.98339536
4MP0001756_abnormal_urination4.27902958
5MP0003880_abnormal_central_pattern3.82070523
6MP0005332_abnormal_amino_acid3.76195118
7MP0004270_analgesia3.60367245
8MP0002139_abnormal_hepatobiliary_system3.28460839
9MP0005365_abnormal_bile_salt3.28259763
10MP0009643_abnormal_urine_homeostasis3.26590850
11MP0005423_abnormal_somatic_nervous3.22386341
12MP0001765_abnormal_ion_homeostasis3.16360715
13MP0002138_abnormal_hepatobiliary_system3.12342208
14MP0004885_abnormal_endolymph2.79529303
15MP0001666_abnormal_nutrient_absorption2.73220374
16MP0002063_abnormal_learning/memory/cond2.68146985
17MP0005085_abnormal_gallbladder_physiolo2.65346736
18MP0002272_abnormal_nervous_system2.58805666
19MP0004019_abnormal_vitamin_homeostasis2.56395055
20MP0003252_abnormal_bile_duct2.49226764
21MP0002136_abnormal_kidney_physiology2.42393999
22MP0005636_abnormal_mineral_homeostasis2.36814828
23MP0003879_abnormal_hair_cell2.27461682
24MP0002572_abnormal_emotion/affect_behav2.26111694
25MP0003329_amyloid_beta_deposits2.21054530
26MP0001501_abnormal_sleep_pattern2.08676400
27MP0009780_abnormal_chondrocyte_physiolo1.98308161
28MP0000538_abnormal_urinary_bladder1.97801677
29MP0002653_abnormal_ependyma_morphology1.95375505
30MP0001984_abnormal_olfaction1.94715667
31MP0008961_abnormal_basal_metabolism1.92867820
32MP0002168_other_aberrant_phenotype1.92321430
33MP0005083_abnormal_biliary_tract1.92125876
34MP0000920_abnormal_myelination1.87605979
35MP0008569_lethality_at_weaning1.85788684
36MP0008875_abnormal_xenobiotic_pharmacok1.83043865
37MP0000569_abnormal_digit_pigmentation1.78203915
38MP0005377_hearing/vestibular/ear_phenot1.74416724
39MP0003878_abnormal_ear_physiology1.74416724
40MP0001970_abnormal_pain_threshold1.74409724
41MP0005646_abnormal_pituitary_gland1.73211692
42MP0002234_abnormal_pharynx_morphology1.71863751
43MP0005220_abnormal_exocrine_pancreas1.71637369
44MP0000778_abnormal_nervous_system1.70423603
45MP0003868_abnormal_feces_composition1.59220480
46MP0002733_abnormal_thermal_nociception1.57275584
47MP0004484_altered_response_of1.53828658
48MP0003634_abnormal_glial_cell1.48140313
49MP0005084_abnormal_gallbladder_morpholo1.47517641
50MP0003632_abnormal_nervous_system1.38570715
51MP0002102_abnormal_ear_morphology1.35236977
52MP0000604_amyloidosis1.34692676
53MP0000955_abnormal_spinal_cord1.34615213
54MP0001270_distended_abdomen1.30494163
55MP0002882_abnormal_neuron_morphology1.24950899
56MP0002066_abnormal_motor_capabilities/c1.24692733
57MP0002557_abnormal_social/conspecific_i1.24495343
58MP0001440_abnormal_grooming_behavior1.22162282
59MP0000566_synostosis1.21755462
60MP0002928_abnormal_bile_duct1.19132429
61MP0005167_abnormal_blood-brain_barrier1.19008796
62MP0005171_absent_coat_pigmentation1.18352725
63MP0005551_abnormal_eye_electrophysiolog1.17727652
64MP0004924_abnormal_behavior1.15095779
65MP0005386_behavior/neurological_phenoty1.15095779
66MP0004811_abnormal_neuron_physiology1.14015116
67MP0003690_abnormal_glial_cell1.11615440
68MP0001905_abnormal_dopamine_level1.09255257
69MP0001958_emphysema1.07561659
70MP0005535_abnormal_body_temperature1.07416828
71MP0005584_abnormal_enzyme/coenzyme_acti1.07299571
72MP0010234_abnormal_vibrissa_follicle1.04914756
73MP0005058_abnormal_lysosome_morphology1.02414879
74MP0002876_abnormal_thyroid_physiology1.02202291
75MP0002229_neurodegeneration1.00685690
76MP0002896_abnormal_bone_mineralization0.99577633
77MP0000534_abnormal_ureter_morphology0.99017564
78MP0000230_abnormal_systemic_arterial0.98669257
79MP0002118_abnormal_lipid_homeostasis0.95742850
80MP0002152_abnormal_brain_morphology0.94238888
81MP0005451_abnormal_body_composition0.93983848
82MP0002735_abnormal_chemical_nociception0.93420211
83MP0003183_abnormal_peptide_metabolism0.92836699
84MP0001764_abnormal_homeostasis0.92142538
85MP0002135_abnormal_kidney_morphology0.90574203
86MP0001963_abnormal_hearing_physiology0.89912152
87MP0010329_abnormal_lipoprotein_level0.87519293
88MP0005165_increased_susceptibility_to0.83373689
89MP0004742_abnormal_vestibular_system0.82466880
90MP0005319_abnormal_enzyme/_coenzyme0.82093315
91MP0002638_abnormal_pupillary_reflex0.81646699
92MP0002909_abnormal_adrenal_gland0.81076756
93MP0004859_abnormal_synaptic_plasticity0.80461736
94MP0003638_abnormal_response/metabolism_0.79481519
95MP0003959_abnormal_lean_body0.79034296
96MP0008874_decreased_physiological_sensi0.77861989
97MP0004130_abnormal_muscle_cell0.77641016
98MP0003633_abnormal_nervous_system0.76948648
99MP0001664_abnormal_digestion0.75998874
100MP0002069_abnormal_eating/drinking_beha0.74756648
101MP0006276_abnormal_autonomic_nervous0.74629765
102MP0002089_abnormal_postnatal_growth/wei0.73849333
103MP0002184_abnormal_innervation0.73640083
104MP0001346_abnormal_lacrimal_gland0.72811947
105MP0004215_abnormal_myocardial_fiber0.72659051
106MP0005395_other_phenotype0.72531229
107MP0003045_fibrosis0.71999206
108MP0001968_abnormal_touch/_nociception0.71076573
109MP0001486_abnormal_startle_reflex0.70834768
110MP0004858_abnormal_nervous_system0.69356288
111MP0009764_decreased_sensitivity_to0.69046872
112MP0000383_abnormal_hair_follicle0.67022041
113MP0003075_altered_response_to0.66230254
114MP0002067_abnormal_sensory_capabilities0.66077886
115MP0003186_abnormal_redox_activity0.65427682
116MP0002822_catalepsy0.65335336
117MP0001727_abnormal_embryo_implantation0.65018321
118MP0002752_abnormal_somatic_nervous0.64111445
119MP0000631_abnormal_neuroendocrine_gland0.63818786
120MP0000678_abnormal_parathyroid_gland0.63309996
121MP0002736_abnormal_nociception_after0.62436832
122MP0004142_abnormal_muscle_tone0.61918909
123MP0005503_abnormal_tendon_morphology0.60940768
124MP0004036_abnormal_muscle_relaxation0.60816016
125MP0003646_muscle_fatigue0.60706821
126MP0003300_gastrointestinal_ulcer0.60488978
127MP0010386_abnormal_urinary_bladder0.60349205
128MP0006036_abnormal_mitochondrial_physio0.60014881
129MP0002734_abnormal_mechanical_nocicepti0.59343849
130MP0000026_abnormal_inner_ear0.58665304
131MP0003136_yellow_coat_color0.58233422
132MP0003631_nervous_system_phenotype0.57684480
133MP0001299_abnormal_eye_distance/0.57475945
134MP0003283_abnormal_digestive_organ0.57302678
135MP0009745_abnormal_behavioral_response0.56458434
136MP0009642_abnormal_blood_homeostasis0.55410821
137MP0009384_cardiac_valve_regurgitation0.54395186
138MP0001177_atelectasis0.54098298
139MP0005623_abnormal_meninges_morphology0.53659496
140MP0003137_abnormal_impulse_conducting0.53188716
141MP0001485_abnormal_pinna_reflex0.52386972
142MP0009250_abnormal_appendicular_skeleto0.51945257
143MP0000579_abnormal_nail_morphology0.51891185
144MP0002064_seizures0.51307383
145MP0000762_abnormal_tongue_morphology0.50044521
146MP0003635_abnormal_synaptic_transmissio0.49659328
147MP0004233_abnormal_muscle_weight0.49609420
148MP0002078_abnormal_glucose_homeostasis0.49162092
149MP0001502_abnormal_circadian_rhythm0.49099800
150MP0003953_abnormal_hormone_level0.47862967
151MP0005595_abnormal_vascular_smooth0.47483272
152MP0005666_abnormal_adipose_tissue0.45902021
153MP0009046_muscle_twitch0.44510286
154MP0003806_abnormal_nucleotide_metabolis0.43980907
155MP0000343_altered_response_to0.43887086
156MP0000609_abnormal_liver_physiology0.43293927

Predicted human phenotypes

RankGene SetZ-score
1Increased circulating renin level (HP:0000848)8.66485995
2Abnormality of chloride homeostasis (HP:0011422)8.49092455
3Polyuria (HP:0000103)8.45055938
4Hyperactive renin-angiotensin system (HP:0000841)8.15847313
5Hypomagnesemia (HP:0002917)7.85035079
6Abnormal urine output (HP:0012590)7.83127076
7Renal salt wasting (HP:0000127)7.41727340
8Hyperaldosteronism (HP:0000859)7.33964276
9Abnormality of renal excretion (HP:0011036)7.09162916
10Tetany (HP:0001281)7.04721380
11Abnormality of magnesium homeostasis (HP:0004921)6.67921985
12Papilledema (HP:0001085)6.62343367
13Abnormal drinking behavior (HP:0030082)6.33457572
14Polydipsia (HP:0001959)6.33457572
15Alkalosis (HP:0001948)6.02247392
16Gout (HP:0001997)5.27564685
17Abnormality of renin-angiotensin system (HP:0000847)5.25542022
18Focal motor seizures (HP:0011153)5.20415685
19Hypokalemia (HP:0002900)4.74806654
20Action tremor (HP:0002345)4.61736805
21Myokymia (HP:0002411)4.52712495
22Focal seizures (HP:0007359)4.09889756
23Abnormality of sodium homeostasis (HP:0010931)4.08538318
24Hypercalciuria (HP:0002150)3.76295870
25Abnormality of potassium homeostasis (HP:0011042)3.75089866
26Diplopia (HP:0000651)3.74916159
27Abnormality of binocular vision (HP:0011514)3.74916159
28Abnormality of fatty-acid metabolism (HP:0004359)3.74347454
29Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.67724407
30Metaphyseal dysplasia (HP:0100255)3.67635787
31Increased purine levels (HP:0004368)3.61946512
32Hyperuricemia (HP:0002149)3.61946512
33Atonic seizures (HP:0010819)3.59825021
34Adrenal overactivity (HP:0002717)3.51456664
35Febrile seizures (HP:0002373)3.48113888
36Hyponatremia (HP:0002902)3.39959595
37Progressive cerebellar ataxia (HP:0002073)3.35854202
38Hyperglycinuria (HP:0003108)3.22937138
39Hemiplegia (HP:0002301)3.15614635
40Neurofibrillary tangles (HP:0002185)3.15404995
41Generalized tonic-clonic seizures (HP:0002069)3.09142279
42Epileptic encephalopathy (HP:0200134)3.01446402
43Hemiparesis (HP:0001269)3.00714522
44Truncal ataxia (HP:0002078)2.95897107
45Ankle clonus (HP:0011448)2.94870035
46Cerebral inclusion bodies (HP:0100314)2.90916158
47Absence seizures (HP:0002121)2.87414040
48Abnormality of purine metabolism (HP:0004352)2.86902762
49Nephrocalcinosis (HP:0000121)2.82665394
50Ketoacidosis (HP:0001993)2.70825382
51Urinary bladder sphincter dysfunction (HP:0002839)2.70362023
52Abnormality of serine family amino acid metabolism (HP:0010894)2.69179815
53Abnormality of glycine metabolism (HP:0010895)2.69179815
54Dehydration (HP:0001944)2.64157127
55Dialeptic seizures (HP:0011146)2.63374425
56Scanning speech (HP:0002168)2.63001179
57Proximal tubulopathy (HP:0000114)2.56356037
58Abnormality of calcium-phosphate metabolism (HP:0100530)2.53832686
59Split foot (HP:0001839)2.50277374
60Abnormality of glutamine family amino acid metabolism (HP:0010902)2.49633943
61Dysdiadochokinesis (HP:0002075)2.48590123
62Supranuclear gaze palsy (HP:0000605)2.47808881
63Hypophosphatemic rickets (HP:0004912)2.40432616
64Tubulointerstitial fibrosis (HP:0005576)2.38208245
65Obstructive sleep apnea (HP:0002870)2.37269056
66Ketosis (HP:0001946)2.34846196
67Megalencephaly (HP:0001355)2.33329205
68Spastic gait (HP:0002064)2.32663583
69Overgrowth (HP:0001548)2.31136917
70Chondrocalcinosis (HP:0000934)2.24133203
71Renal tubular acidosis (HP:0001947)2.24066816
72Intention tremor (HP:0002080)2.23478504
73Postural instability (HP:0002172)2.18321213
74Abnormality of Sharpey fibers (HP:0100685)2.13069134
75Mild short stature (HP:0003502)2.12685204
76Decreased circulating renin level (HP:0003351)2.12154891
77Mutism (HP:0002300)2.07548660
78Neonatal onset (HP:0003623)2.06505576
79Vomiting (HP:0002013)2.04694554
80Delayed CNS myelination (HP:0002188)2.04690269
81Dysmetria (HP:0001310)2.04241895
82Choanal stenosis (HP:0000452)2.02810477
83Epileptiform EEG discharges (HP:0011182)2.01155656
84Metabolic alkalosis (HP:0200114)11.2614072
85Hypokalemic alkalosis (HP:0001949)10.2166364
86Hypotension (HP:0002615)1.99879096
87Dysmetric saccades (HP:0000641)1.99873420
88Abnormality of aspartate family amino acid metabolism (HP:0010899)1.99574921
89Aplasia involving bones of the upper limbs (HP:0009823)1.96215093
90Aplasia of the phalanges of the hand (HP:0009802)1.96215093
91Aplasia involving bones of the extremities (HP:0009825)1.96215093
92Lower limb muscle weakness (HP:0007340)1.95594515
93Sudden death (HP:0001699)1.92788099
94Hyperglycinemia (HP:0002154)1.92665225
95Impaired vibration sensation in the lower limbs (HP:0002166)1.91993218
96Torticollis (HP:0000473)1.91970485
97Anxiety (HP:0000739)1.91760423
98Urinary urgency (HP:0000012)1.91741741
99Gaze-evoked nystagmus (HP:0000640)1.90304661
100Generalized aminoaciduria (HP:0002909)1.89831517
101Abnormality of nucleobase metabolism (HP:0010932)1.89219061
102Large eyes (HP:0001090)1.88960022
103Craniofacial hyperostosis (HP:0004493)1.88766120
104Increased density of long bones (HP:0006392)1.87820061
105Peripheral hypomyelination (HP:0007182)1.86401886
106Tubular atrophy (HP:0000092)1.84194554
107Pheochromocytoma (HP:0002666)1.83027146
108Enlarged epiphyses (HP:0010580)1.82920472
109Abnormality of sulfur amino acid metabolism (HP:0004339)1.80668440
110Spinal canal stenosis (HP:0003416)1.78141288
111Generalized muscle weakness (HP:0003324)1.76888028
112Genetic anticipation (HP:0003743)1.76750953
113Abnormality of dicarboxylic acid metabolism (HP:0010995)1.76273059
114Dicarboxylic aciduria (HP:0003215)1.76273059
115Abnormality of aromatic amino acid family metabolism (HP:0004338)1.74827665
116Tetraplegia (HP:0002445)1.74338999
117Facial diplegia (HP:0001349)1.73469455
118Glomerulosclerosis (HP:0000096)1.72125099
119Abnormality of incisor morphology (HP:0011063)1.70833137
120Abnormality of urine glucose concentration (HP:0011016)1.70684399
121Glycosuria (HP:0003076)1.70684399
122Hyperammonemia (HP:0001987)1.70682266
123Cranial hyperostosis (HP:0004437)1.68880680
124Neoplasm of the heart (HP:0100544)1.66962776
125Postural tremor (HP:0002174)1.66374109
126Abnormality of the renal cortex (HP:0011035)1.65938731
127Hydroxyprolinuria (HP:0003080)1.65670244
128Abnormality of proline metabolism (HP:0010907)1.65670244
129EEG with generalized epileptiform discharges (HP:0011198)1.64405230
130Focal dystonia (HP:0004373)1.63641315
131Potter facies (HP:0002009)1.62769602
132Facial shape deformation (HP:0011334)1.62769602
133Impaired vibratory sensation (HP:0002495)1.61069277
134Poor eye contact (HP:0000817)1.60733997
135Abnormality of the diencephalon (HP:0010662)1.60352811
136Confusion (HP:0001289)1.59961592
137Metaphyseal cupping (HP:0003021)1.58243235
138Neuroendocrine neoplasm (HP:0100634)1.57859748
139Alacrima (HP:0000522)1.57822464
140Neuronal loss in central nervous system (HP:0002529)1.56591156
141Methylmalonic aciduria (HP:0012120)1.56252536
142Nephrolithiasis (HP:0000787)1.54573699
143Tubulointerstitial abnormality (HP:0001969)1.51720156
144Spastic paraparesis (HP:0002313)1.47966385
145Metabolic acidosis (HP:0001942)1.47807417
146Irritability (HP:0000737)1.47570127
147Impaired platelet aggregation (HP:0003540)1.46750702
148Abnormal platelet function (HP:0011869)1.46750702
149Vascular calcification (HP:0004934)1.42961915
150Abnormal tarsal ossification (HP:0008369)1.42466638
151Lethargy (HP:0001254)1.40386397
152Unilateral renal agenesis (HP:0000122)1.36122662
153Elfin facies (HP:0004428)1.35809660
154Renal tubular dysfunction (HP:0000124)1.30789977
155Hypophosphatemia (HP:0002148)1.29317072
156Abnormality of the renal medulla (HP:0100957)1.27925198
157Abnormal eating behavior (HP:0100738)1.27316901
158Cardiovascular calcification (HP:0011915)1.25483348
159Hyperphosphaturia (HP:0003109)1.25240588
160Sensorimotor neuropathy (HP:0007141)1.23146890
161Abnormal urine phosphate concentration (HP:0012599)1.19435961
162Enlarged kidneys (HP:0000105)1.18150187
163Hyperventilation (HP:0002883)1.17891790
164Abnormality of serum amino acid levels (HP:0003112)1.17364674
165Rickets (HP:0002748)1.16285656
166Status epilepticus (HP:0002133)1.14602035
167Abnormality of renal resorption (HP:0011038)1.13719232
168Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.13215183
169Tachypnea (HP:0002789)1.12366062
170Pancreatitis (HP:0001733)1.08275522
171Widely patent fontanelles and sutures (HP:0004492)1.05718931
172Intrahepatic cholestasis (HP:0001406)1.03774267
173Hyperkalemia (HP:0002153)1.03568757

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OXSR16.74850954
2WNK45.11776371
3BCKDK3.13618644
4CASK2.88339887
5SGK22.35211684
6SGK2232.23586764
7SGK4942.23586764
8WNK311.4496885
9SGK31.87854253
10UHMK11.72642158
11STK391.65760949
12NTRK11.64801599
13IRAK31.62839521
14MST41.57529118
15WNK11.53692371
16FRK1.34497832
17TYRO31.31863145
18LATS21.26299745
19MAPK131.25353263
20PKN11.18471160
21PLK21.17844893
22NTRK21.06740965
23PNCK1.06532468
24MST1R1.06212371
25AKT31.04633347
26CAMK2G1.03206406
27KSR20.97948453
28DMPK0.97049740
29PDK40.95418845
30PDK30.95418845
31PRPF4B0.94987717
32MAP3K90.94008564
33CAMK2A0.93618694
34SGK10.86756619
35FGFR20.86116588
36MUSK0.85611175
37TNK20.82835144
38TNIK0.81196958
39OBSCN0.79837684
40STK380.77872073
41MAP3K40.76513107
42MAPK100.76486603
43PDK20.73349069
44NEK60.72858930
45GRK50.71913132
46PINK10.71323969
47TIE10.71120903
48ARAF0.70937228
49ERN10.69545005
50MAP3K130.68410651
51PAK30.67712564
52MAP3K70.67008473
53NTRK30.66423406
54EPHA30.66169284
55STK38L0.65998170
56MARK20.63157833
57EPHA40.63132654
58RIPK40.62025143
59CAMK2D0.61601400
60ROCK10.60822786
61PRKD20.58543648
62ROCK20.58379530
63CDK150.57386657
64PDGFRA0.57370073
65TRIB30.55843436
66DYRK1A0.55601812
67CAMK1D0.55313625
68LATS10.54129484
69CDK180.52712770
70BMPR20.52095312
71DAPK10.51725073
72PDGFRB0.51706612
73MAP3K20.51415139
74CAMKK10.51256452
75IRAK20.51052553
76PRKCE0.50076265
77DAPK20.49570307
78CDK140.48849902
79PIK3CA0.48803512
80JAK10.48369576
81RET0.48117631
82CDK11A0.47790910
83PRKCH0.47781068
84PRKAA10.46986484
85CAMK1G0.46683836
86BMX0.46464291
87RIPK10.45803912
88MAPK70.43373637
89PAK60.42916051
90SIK10.41022149
91CAMK40.40864735
92PDPK10.40337435
93DDR20.39639150
94PRKG10.39454597
95LMTK20.39429479
96PTK2B0.39021688
97CCNB10.37327263
98MAPK120.36549081
99PRKAA20.35960099
100MINK10.35583380
101ERBB20.35191603
102MAPK40.34571951
103PHKG20.34275296
104PHKG10.34275296
105PRKCZ0.34257524
106FYN0.33726158
107BMPR1B0.33640740
108MAPKAPK50.33590847
109PRKD30.29227819
110IRAK10.29094806
111INSRR0.28058680
112MARK10.27893759
113PDK10.27633244
114TGFBR20.27363350
115PTK60.27048813
116MET0.26061460
117IKBKE0.26061073
118CSNK1A10.25270891
119NEK10.23702890
120MAPK110.23584315
121CDK50.22272492
122GRK10.22166877
123PRKACG0.22006396
124EIF2AK30.20420495
125IRAK40.20207098
126PRKACA0.20065691
127CAMKK20.19535643
128MAPK150.19525830
129LRRK20.18963420
130STK110.18726444
131GSK3A0.18026556
132RPS6KA30.17064698
133TBK10.16036593
134PRKCG0.15380281
135AKT20.14742775
136PRKCA0.13491759
137TAOK20.13447128
138PKN20.13318900
139FER0.12549948
140PRKCD0.11731411
141EPHB10.10874109
142CSNK1G20.10347797
143PTK20.10112807
144FGFR40.09452275
145MAP2K10.09339265
146PRKACB0.09200616
147CAMK10.09052681
148CAMK2B0.08691140
149MAP2K40.08080628
150ABL20.07975157
151CSNK1E0.07050162

Predicted pathways (KEGG)

RankGene SetZ-score
1Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049644.21552703
2Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.29631751
3Nicotine addiction_Homo sapiens_hsa050333.16572357
4Propanoate metabolism_Homo sapiens_hsa006403.15336071
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.06962925
6Butanoate metabolism_Homo sapiens_hsa006502.87969420
7Nitrogen metabolism_Homo sapiens_hsa009102.65606086
82-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.62399666
9Fatty acid degradation_Homo sapiens_hsa000712.45545997
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.43506343
11Long-term potentiation_Homo sapiens_hsa047202.24282065
12Circadian entrainment_Homo sapiens_hsa047132.23048899
13Vitamin digestion and absorption_Homo sapiens_hsa049772.21565899
14Protein digestion and absorption_Homo sapiens_hsa049742.18736770
15Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.15805101
16Amphetamine addiction_Homo sapiens_hsa050312.10934916
17Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049602.10116784
18Cyanoamino acid metabolism_Homo sapiens_hsa004602.07672474
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.01072363
20Morphine addiction_Homo sapiens_hsa050321.98245234
21Fatty acid metabolism_Homo sapiens_hsa012121.96268262
22Bile secretion_Homo sapiens_hsa049761.95643169
23Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.94379804
24Pancreatic secretion_Homo sapiens_hsa049721.92223683
25Tryptophan metabolism_Homo sapiens_hsa003801.87801111
26Peroxisome_Homo sapiens_hsa041461.78767523
27Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.76093391
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.75710717
29Dopaminergic synapse_Homo sapiens_hsa047281.69760320
30Pentose and glucuronate interconversions_Homo sapiens_hsa000401.65329415
31Cocaine addiction_Homo sapiens_hsa050301.57947577
32PPAR signaling pathway_Homo sapiens_hsa033201.53716867
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.52285908
34Pyruvate metabolism_Homo sapiens_hsa006201.44859247
35Sulfur metabolism_Homo sapiens_hsa009201.43856687
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.43765468
37beta-Alanine metabolism_Homo sapiens_hsa004101.41754530
38Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.38573894
39Arginine biosynthesis_Homo sapiens_hsa002201.36065057
40Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.33841130
41Calcium signaling pathway_Homo sapiens_hsa040201.28787222
42Primary bile acid biosynthesis_Homo sapiens_hsa001201.28653954
43Collecting duct acid secretion_Homo sapiens_hsa049661.28057250
44Cholinergic synapse_Homo sapiens_hsa047251.27786657
45Glycerolipid metabolism_Homo sapiens_hsa005611.22640839
46Oxytocin signaling pathway_Homo sapiens_hsa049211.20216802
47Mineral absorption_Homo sapiens_hsa049781.18680907
48Carbon metabolism_Homo sapiens_hsa012001.15854531
49Gastric acid secretion_Homo sapiens_hsa049711.13419536
50Glioma_Homo sapiens_hsa052141.09729879
51Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.01684985
52Dorso-ventral axis formation_Homo sapiens_hsa043201.00454876
53Estrogen signaling pathway_Homo sapiens_hsa049151.00273605
54Phospholipase D signaling pathway_Homo sapiens_hsa040721.00117184
55Arginine and proline metabolism_Homo sapiens_hsa003300.98388244
56Prion diseases_Homo sapiens_hsa050200.97788726
57Biosynthesis of amino acids_Homo sapiens_hsa012300.96787198
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.96620912
59Long-term depression_Homo sapiens_hsa047300.96373017
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.95071106
61Folate biosynthesis_Homo sapiens_hsa007900.93498080
62Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92360208
63Starch and sucrose metabolism_Homo sapiens_hsa005000.91767783
64Serotonergic synapse_Homo sapiens_hsa047260.91313048
65Gap junction_Homo sapiens_hsa045400.90477734
66ABC transporters_Homo sapiens_hsa020100.89812331
67Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.89587565
68Fat digestion and absorption_Homo sapiens_hsa049750.88341126
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.85770884
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84550603
71ErbB signaling pathway_Homo sapiens_hsa040120.82037239
72Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.80611440
73Steroid biosynthesis_Homo sapiens_hsa001000.80475417
74Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79277022
75Melanogenesis_Homo sapiens_hsa049160.77685017
76GnRH signaling pathway_Homo sapiens_hsa049120.76340414
77Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.74899497
78Thyroid hormone synthesis_Homo sapiens_hsa049180.73687113
79Glutathione metabolism_Homo sapiens_hsa004800.73606505
80Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70403927
81Olfactory transduction_Homo sapiens_hsa047400.68993280
82Lysine degradation_Homo sapiens_hsa003100.66300535
83Histidine metabolism_Homo sapiens_hsa003400.65573951
84Chemical carcinogenesis_Homo sapiens_hsa052040.63448079
85Choline metabolism in cancer_Homo sapiens_hsa052310.63435378
86Rap1 signaling pathway_Homo sapiens_hsa040150.63189448
87Phenylalanine metabolism_Homo sapiens_hsa003600.62800050
88Cysteine and methionine metabolism_Homo sapiens_hsa002700.62331955
89Taste transduction_Homo sapiens_hsa047420.62147657
90Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62001070
91Salivary secretion_Homo sapiens_hsa049700.60054360
92Ras signaling pathway_Homo sapiens_hsa040140.58332068
93Insulin secretion_Homo sapiens_hsa049110.57790798
94ECM-receptor interaction_Homo sapiens_hsa045120.57757601
95Dilated cardiomyopathy_Homo sapiens_hsa054140.57697551
96Fatty acid biosynthesis_Homo sapiens_hsa000610.57666491
97Type II diabetes mellitus_Homo sapiens_hsa049300.57283051
98Fatty acid elongation_Homo sapiens_hsa000620.56661838
99Axon guidance_Homo sapiens_hsa043600.56635100
100Fructose and mannose metabolism_Homo sapiens_hsa000510.55743282
101Inositol phosphate metabolism_Homo sapiens_hsa005620.55015007
102Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.54772266
103Steroid hormone biosynthesis_Homo sapiens_hsa001400.54496662
104Maturity onset diabetes of the young_Homo sapiens_hsa049500.54478485
105Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54303874
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.49348869
107Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49280058
108MAPK signaling pathway_Homo sapiens_hsa040100.48973553
109mTOR signaling pathway_Homo sapiens_hsa041500.46536328
110Selenocompound metabolism_Homo sapiens_hsa004500.46446007
111Glycosaminoglycan degradation_Homo sapiens_hsa005310.45809806
112Cardiac muscle contraction_Homo sapiens_hsa042600.44485785
113Other glycan degradation_Homo sapiens_hsa005110.43830057
114Oxidative phosphorylation_Homo sapiens_hsa001900.43406159
115Renin-angiotensin system_Homo sapiens_hsa046140.42691284
116Oocyte meiosis_Homo sapiens_hsa041140.41775492
117Hippo signaling pathway_Homo sapiens_hsa043900.38929783
118Synaptic vesicle cycle_Homo sapiens_hsa047210.38861073
119Focal adhesion_Homo sapiens_hsa045100.37929862
120AMPK signaling pathway_Homo sapiens_hsa041520.37534916
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.35566559
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35050321
123Vibrio cholerae infection_Homo sapiens_hsa051100.33679773
124Retinol metabolism_Homo sapiens_hsa008300.33506890
125Vitamin B6 metabolism_Homo sapiens_hsa007500.33202210
126Metabolic pathways_Homo sapiens_hsa011000.32900456
127GABAergic synapse_Homo sapiens_hsa047270.30482482
128Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.28881414
129Insulin resistance_Homo sapiens_hsa049310.28381966
130Glucagon signaling pathway_Homo sapiens_hsa049220.27600935
131Glutamatergic synapse_Homo sapiens_hsa047240.27377076
132Renin secretion_Homo sapiens_hsa049240.26704634
133Alzheimers disease_Homo sapiens_hsa050100.26452039
134Lysosome_Homo sapiens_hsa041420.25235106
135Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.24880550
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.22997952
137cAMP signaling pathway_Homo sapiens_hsa040240.19980252
138Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.15773880
139Tyrosine metabolism_Homo sapiens_hsa003500.13503009
140Aldosterone synthesis and secretion_Homo sapiens_hsa049250.12909655
141Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.11837823
142Endometrial cancer_Homo sapiens_hsa052130.11169198
143Hepatitis C_Homo sapiens_hsa051600.10838181
144Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.09713077
145Circadian rhythm_Homo sapiens_hsa047100.09489621
146Complement and coagulation cascades_Homo sapiens_hsa046100.09294172
147cGMP-PKG signaling pathway_Homo sapiens_hsa040220.09284789
148Parkinsons disease_Homo sapiens_hsa050120.09188758

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