Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 4.63241488 |
2 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.45077369 |
3 | Golgi transport vesicle coating (GO:0048200) | 4.36901209 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 4.36901209 |
5 | mitotic sister chromatid segregation (GO:0000070) | 4.31228206 |
6 | regulation of translational termination (GO:0006449) | 4.27321469 |
7 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 4.26956783 |
8 | protein localization to kinetochore (GO:0034501) | 4.12681855 |
9 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 4.11052379 |
10 | sister chromatid segregation (GO:0000819) | 4.07410144 |
11 | negative regulation of microtubule polymerization (GO:0031115) | 4.02043167 |
12 | peptidyl-arginine methylation (GO:0018216) | 3.90611991 |
13 | peptidyl-arginine N-methylation (GO:0035246) | 3.90611991 |
14 | DNA packaging (GO:0006323) | 3.89383282 |
15 | protein localization to endosome (GO:0036010) | 3.88503652 |
16 | activation of Rac GTPase activity (GO:0032863) | 3.88474472 |
17 | adherens junction assembly (GO:0034333) | 3.86454803 |
18 | histone arginine methylation (GO:0034969) | 3.83618034 |
19 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.82880312 |
20 | regulation of translational fidelity (GO:0006450) | 3.76836523 |
21 | proline biosynthetic process (GO:0006561) | 3.76479917 |
22 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.75254072 |
23 | protein retention in ER lumen (GO:0006621) | 3.75169020 |
24 | focal adhesion assembly (GO:0048041) | 3.73505626 |
25 | cell-substrate adherens junction assembly (GO:0007045) | 3.73505626 |
26 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.73408381 |
27 | pre-miRNA processing (GO:0031054) | 3.71466905 |
28 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.67424982 |
29 | protein localization to chromosome, centromeric region (GO:0071459) | 3.61779990 |
30 | synaptic vesicle maturation (GO:0016188) | 3.61169386 |
31 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.58434069 |
32 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.56972416 |
33 | cellular protein complex localization (GO:0034629) | 3.51942593 |
34 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.47878728 |
35 | cell-substrate junction assembly (GO:0007044) | 3.45490833 |
36 | positive regulation of synapse maturation (GO:0090129) | 3.39928239 |
37 | layer formation in cerebral cortex (GO:0021819) | 3.37209290 |
38 | hemidesmosome assembly (GO:0031581) | 3.36014150 |
39 | nuclear pore organization (GO:0006999) | 3.35058239 |
40 | negative regulation of cell size (GO:0045792) | 3.33483564 |
41 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.31435331 |
42 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.31435331 |
43 | mitotic nuclear envelope disassembly (GO:0007077) | 3.30620691 |
44 | nuclear envelope disassembly (GO:0051081) | 3.28645597 |
45 | membrane disassembly (GO:0030397) | 3.28645597 |
46 | regulation of early endosome to late endosome transport (GO:2000641) | 3.23653802 |
47 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.22106864 |
48 | nuclear pore complex assembly (GO:0051292) | 3.20946866 |
49 | protein-DNA complex disassembly (GO:0032986) | 3.18243802 |
50 | nucleosome disassembly (GO:0006337) | 3.18243802 |
51 | apoptotic process involved in morphogenesis (GO:0060561) | 3.16439890 |
52 | heterochromatin organization (GO:0070828) | 3.14724318 |
53 | glutamate secretion (GO:0014047) | 3.13746683 |
54 | mitotic G1/S transition checkpoint (GO:0044819) | 3.13657854 |
55 | G1 DNA damage checkpoint (GO:0044783) | 3.11830861 |
56 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.09986140 |
57 | chaperone-mediated protein complex assembly (GO:0051131) | 3.09935999 |
58 | protein maturation by protein folding (GO:0022417) | 3.05861857 |
59 | synaptic vesicle exocytosis (GO:0016079) | 3.02133644 |
60 | pore complex assembly (GO:0046931) | 3.01592145 |
61 | nuclear envelope reassembly (GO:0031468) | 3.00089735 |
62 | mitotic nuclear envelope reassembly (GO:0007084) | 3.00089735 |
63 | formation of translation preinitiation complex (GO:0001731) | 2.97984739 |
64 | positive regulation of chromosome segregation (GO:0051984) | 2.96320552 |
65 | DNA replication initiation (GO:0006270) | 2.91831535 |
66 | mitotic metaphase plate congression (GO:0007080) | 2.91574340 |
67 | cell migration in hindbrain (GO:0021535) | 2.89596159 |
68 | establishment of apical/basal cell polarity (GO:0035089) | 2.89041525 |
69 | cerebellar Purkinje cell layer development (GO:0021680) | 2.89032604 |
70 | DNA conformation change (GO:0071103) | 2.88247155 |
71 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.88235579 |
72 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.85536751 |
73 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.85112266 |
74 | IMP biosynthetic process (GO:0006188) | 2.84769254 |
75 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.84399798 |
76 | protein complex localization (GO:0031503) | 2.83852668 |
77 | maturation of SSU-rRNA (GO:0030490) | 2.81533823 |
78 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.81508298 |
79 | protein export from nucleus (GO:0006611) | 2.81174214 |
80 | nucleobase biosynthetic process (GO:0046112) | 2.79601184 |
81 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.78103100 |
82 | DNA duplex unwinding (GO:0032508) | 2.77051896 |
83 | DNA geometric change (GO:0032392) | 2.74871604 |
84 | mitotic chromosome condensation (GO:0007076) | 2.74839365 |
85 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.73006244 |
86 | regulation of gene silencing by miRNA (GO:0060964) | 2.73006244 |
87 | regulation of gene silencing by RNA (GO:0060966) | 2.73006244 |
88 | regulation of chromosome segregation (GO:0051983) | 2.72257794 |
89 | regulation of translational elongation (GO:0006448) | 2.70426516 |
90 | maternal placenta development (GO:0001893) | 2.68328930 |
91 | locomotory exploration behavior (GO:0035641) | 2.68124598 |
92 | regulation of spindle organization (GO:0090224) | 2.67892336 |
93 | mitotic spindle organization (GO:0007052) | 2.67678145 |
94 | microtubule depolymerization (GO:0007019) | 2.64119045 |
95 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.63842950 |
96 | regulation of histone H3-K27 methylation (GO:0061085) | 2.62434855 |
97 | protein localization to chromosome (GO:0034502) | 2.62209085 |
98 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.62164900 |
99 | DNA strand elongation (GO:0022616) | 2.60361012 |
100 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.60341898 |
101 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.60041279 |
102 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.59412833 |
103 | nuclear envelope organization (GO:0006998) | 2.59399152 |
104 | positive regulation of nuclease activity (GO:0032075) | 2.59085426 |
105 | sodium ion export (GO:0071436) | 2.58525472 |
106 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.58134778 |
107 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.58134778 |
108 | negative regulation of chromosome segregation (GO:0051985) | 2.56003694 |
109 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.56002681 |
110 | negative regulation of histone methylation (GO:0031061) | 2.55937411 |
111 | regulation of centrosome cycle (GO:0046605) | 2.55580305 |
112 | semaphorin-plexin signaling pathway (GO:0071526) | 2.54183327 |
113 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.53988339 |
114 | peptidyl-lysine dimethylation (GO:0018027) | 2.53330429 |
115 | desmosome organization (GO:0002934) | 2.52524262 |
116 | neurotransmitter secretion (GO:0007269) | 2.51970470 |
117 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.51048769 |
118 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.51048769 |
119 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.51048769 |
120 | chromosome condensation (GO:0030261) | 2.50094689 |
121 | basement membrane organization (GO:0071711) | 2.49486929 |
122 | rRNA transcription (GO:0009303) | 2.46362273 |
123 | metaphase plate congression (GO:0051310) | 2.46169108 |
124 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 2.46095903 |
125 | vocalization behavior (GO:0071625) | 2.44123953 |
126 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.43984167 |
127 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.43984167 |
128 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.43984167 |
129 | negative regulation of sister chromatid segregation (GO:0033046) | 2.43984167 |
130 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.43856946 |
131 | proline metabolic process (GO:0006560) | 2.43496027 |
132 | mitotic spindle assembly checkpoint (GO:0007094) | 2.43213663 |
133 | regulation of mitotic spindle organization (GO:0060236) | 2.43101707 |
134 | epithelial cell-cell adhesion (GO:0090136) | 2.42960519 |
135 | ribosome biogenesis (GO:0042254) | 2.42700234 |
136 | establishment of chromosome localization (GO:0051303) | 2.42428120 |
137 | spindle assembly checkpoint (GO:0071173) | 2.42168169 |
138 | spindle checkpoint (GO:0031577) | 2.42039112 |
139 | dendritic spine morphogenesis (GO:0060997) | 2.41737020 |
140 | convergent extension (GO:0060026) | 2.41626320 |
141 | protein localization to synapse (GO:0035418) | 2.41253152 |
142 | stress fiber assembly (GO:0043149) | 2.41002834 |
143 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.40931879 |
144 | protein targeting to plasma membrane (GO:0072661) | 2.40896670 |
145 | mitotic spindle checkpoint (GO:0071174) | 2.40154084 |
146 | regulation of RNA export from nucleus (GO:0046831) | 2.38428200 |
147 | positive regulation of protein dephosphorylation (GO:0035307) | 2.38329255 |
148 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.38320237 |
149 | negative regulation of organelle assembly (GO:1902116) | 2.37249236 |
150 | negative regulation of microtubule polymerization or depolymerization (GO:0031111) | 2.34699041 |
151 | regulation of sister chromatid segregation (GO:0033045) | 2.34066012 |
152 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.34066012 |
153 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.34066012 |
154 | tRNA aminoacylation for protein translation (GO:0006418) | 2.33809804 |
155 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.33781354 |
156 | spliceosomal snRNP assembly (GO:0000387) | 2.33637786 |
157 | spindle assembly involved in mitosis (GO:0090307) | 2.33384220 |
158 | regulation of sister chromatid cohesion (GO:0007063) | 2.32331210 |
159 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.31865007 |
160 | establishment of integrated proviral latency (GO:0075713) | 2.31799393 |
161 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.31633569 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.08831490 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.47918865 |
3 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.53892380 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.51841082 |
5 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.10295343 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.05884536 |
7 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.97959153 |
8 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.90349766 |
9 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.52700721 |
10 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.46761436 |
11 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.28332409 |
12 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.26650267 |
13 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.25975631 |
14 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.24921600 |
15 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.19160080 |
16 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.15151007 |
17 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.14331837 |
18 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.13095003 |
19 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.02026622 |
20 | MYC_22102868_ChIP-Seq_BL_Human | 2.00664286 |
21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.00382592 |
22 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.95771291 |
23 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.94430044 |
24 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.94366956 |
25 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.93072414 |
26 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.92941369 |
27 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.92241459 |
28 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.90991995 |
29 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.90526408 |
30 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.88864246 |
31 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.87895105 |
32 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.87451881 |
33 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.84365731 |
34 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.83202489 |
35 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.76960082 |
36 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.76818251 |
37 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.75413382 |
38 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.75169631 |
39 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.71392053 |
40 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.65074337 |
41 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.64249281 |
42 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.62669365 |
43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.62591327 |
44 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.62448408 |
45 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.61825913 |
46 | KDM2B_26808549_Chip-Seq_K562_Human | 1.60187106 |
47 | P68_20966046_ChIP-Seq_HELA_Human | 1.60059266 |
48 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.58008874 |
49 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.56506993 |
50 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.55316867 |
51 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.50151110 |
52 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.49887193 |
53 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.48414945 |
54 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.47885644 |
55 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.47880394 |
56 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.47847555 |
57 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.47741597 |
58 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.46839991 |
59 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.46700674 |
60 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.46105007 |
61 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.45577763 |
62 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.43484777 |
63 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.42658814 |
64 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.41198237 |
65 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.41052153 |
66 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.40895716 |
67 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.40718650 |
68 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.39876933 |
69 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.39793614 |
70 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.39756942 |
71 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.39455743 |
72 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.38875536 |
73 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.37819468 |
74 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.37606027 |
75 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.35356719 |
76 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.34321410 |
77 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.34154457 |
78 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.33753906 |
79 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.32601028 |
80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.31795263 |
81 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.29854254 |
82 | * TP53_22127205_ChIP-Seq_IMR90_Human | 1.29287385 |
83 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.28866498 |
84 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.27923770 |
85 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.26102151 |
86 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.25143398 |
87 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.24905469 |
88 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.24542958 |
89 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.24317413 |
90 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.23904339 |
91 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.23825221 |
92 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.23669915 |
93 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.22845968 |
94 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.22172470 |
95 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.22116277 |
96 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.22097428 |
97 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.21785342 |
98 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.20959598 |
99 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.20803777 |
100 | * HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.20803276 |
101 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.20013362 |
102 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17738030 |
103 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.17227291 |
104 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.16731189 |
105 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.12727111 |
106 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.11838750 |
107 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.11139619 |
108 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.10337986 |
109 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.10155585 |
110 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.09179407 |
111 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.08569821 |
112 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.08495762 |
113 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.06372935 |
114 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.05149491 |
115 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.04372685 |
116 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.04342653 |
117 | * RARA_24833708_ChIP-Seq_LIVER_Mouse | 1.04261296 |
118 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.04040321 |
119 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.03709155 |
120 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.03623563 |
121 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.03432402 |
122 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.03107911 |
123 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.03036399 |
124 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.02716861 |
125 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.02611216 |
126 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02347047 |
127 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.01970271 |
128 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.00882320 |
129 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.00602768 |
130 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.00449565 |
131 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.00177180 |
132 | * VDR_23849224_ChIP-Seq_CD4+_Human | 0.99850194 |
133 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.98838356 |
134 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.98579366 |
135 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.98573368 |
136 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.98334973 |
137 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.98299127 |
138 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.98088276 |
139 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.98056845 |
140 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.97817151 |
141 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.97284255 |
142 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.96331825 |
143 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.95982867 |
144 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95612690 |
145 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.95124938 |
146 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.94700674 |
147 | MAF_26560356_Chip-Seq_TH2_Human | 0.94500814 |
148 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.94257083 |
149 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.94220149 |
150 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.94148482 |
151 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.93850102 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 3.90481740 |
2 | MP0003123_paternal_imprinting | 3.34911710 |
3 | MP0003693_abnormal_embryo_hatching | 3.20507061 |
4 | MP0003111_abnormal_nucleus_morphology | 3.15335669 |
5 | MP0002877_abnormal_melanocyte_morpholog | 2.83759483 |
6 | MP0004957_abnormal_blastocyst_morpholog | 2.80977503 |
7 | MP0003566_abnormal_cell_adhesion | 2.72615301 |
8 | MP0010094_abnormal_chromosome_stability | 2.52214681 |
9 | MP0005451_abnormal_body_composition | 2.51485798 |
10 | MP0003283_abnormal_digestive_organ | 2.50621285 |
11 | MP0003635_abnormal_synaptic_transmissio | 2.44585213 |
12 | MP0003880_abnormal_central_pattern | 2.36843644 |
13 | MP0003122_maternal_imprinting | 2.36396608 |
14 | MP0003077_abnormal_cell_cycle | 2.29875258 |
15 | MP0004270_analgesia | 2.19925898 |
16 | MP0001968_abnormal_touch/_nociception | 2.08547677 |
17 | * MP0001730_embryonic_growth_arrest | 2.02863723 |
18 | MP0000537_abnormal_urethra_morphology | 2.00699511 |
19 | MP0002796_impaired_skin_barrier | 1.94847342 |
20 | MP0003121_genomic_imprinting | 1.93796954 |
21 | MP0002063_abnormal_learning/memory/cond | 1.92990302 |
22 | MP0008438_abnormal_cutaneous_collagen | 1.91648152 |
23 | MP0005423_abnormal_somatic_nervous | 1.84496547 |
24 | MP0000678_abnormal_parathyroid_gland | 1.82054491 |
25 | MP0005257_abnormal_intraocular_pressure | 1.80787769 |
26 | MP0003119_abnormal_digestive_system | 1.80566103 |
27 | MP0004185_abnormal_adipocyte_glucose | 1.79523988 |
28 | MP0000003_abnormal_adipose_tissue | 1.79067239 |
29 | MP0008057_abnormal_DNA_replication | 1.78914915 |
30 | MP0008877_abnormal_DNA_methylation | 1.71103392 |
31 | MP0003091_abnormal_cell_migration | 1.69982332 |
32 | MP0005501_abnormal_skin_physiology | 1.69816072 |
33 | MP0004811_abnormal_neuron_physiology | 1.69238746 |
34 | MP0002653_abnormal_ependyma_morphology | 1.68846846 |
35 | MP0004858_abnormal_nervous_system | 1.67635398 |
36 | MP0009745_abnormal_behavioral_response | 1.67474085 |
37 | MP0004272_abnormal_basement_membrane | 1.67294432 |
38 | MP0003453_abnormal_keratinocyte_physiol | 1.66961050 |
39 | MP0008260_abnormal_autophagy | 1.66648339 |
40 | MP0000350_abnormal_cell_proliferation | 1.65733267 |
41 | MP0002736_abnormal_nociception_after | 1.63877759 |
42 | MP0002064_seizures | 1.63267553 |
43 | MP0002733_abnormal_thermal_nociception | 1.61743370 |
44 | MP0010234_abnormal_vibrissa_follicle | 1.61406046 |
45 | MP0008932_abnormal_embryonic_tissue | 1.61258662 |
46 | MP0010352_gastrointestinal_tract_polyps | 1.59224373 |
47 | MP0002089_abnormal_postnatal_growth/wei | 1.58193209 |
48 | MP0000579_abnormal_nail_morphology | 1.56284539 |
49 | MP0002734_abnormal_mechanical_nocicepti | 1.55888083 |
50 | MP0002060_abnormal_skin_morphology | 1.50389161 |
51 | MP0006276_abnormal_autonomic_nervous | 1.48468500 |
52 | MP0005409_darkened_coat_color | 1.46750873 |
53 | MP0005076_abnormal_cell_differentiation | 1.46446518 |
54 | * MP0002084_abnormal_developmental_patter | 1.43289187 |
55 | MP0001529_abnormal_vocalization | 1.42464259 |
56 | MP0004233_abnormal_muscle_weight | 1.42414544 |
57 | MP0009046_muscle_twitch | 1.41463687 |
58 | MP0002184_abnormal_innervation | 1.40617473 |
59 | * MP0001697_abnormal_embryo_size | 1.39389051 |
60 | MP0002572_abnormal_emotion/affect_behav | 1.39223014 |
61 | MP0003890_abnormal_embryonic-extraembry | 1.38646684 |
62 | MP0002909_abnormal_adrenal_gland | 1.37839075 |
63 | MP0008007_abnormal_cellular_replicative | 1.35151871 |
64 | MP0001440_abnormal_grooming_behavior | 1.34959412 |
65 | MP0004197_abnormal_fetal_growth/weight/ | 1.33774501 |
66 | MP0002249_abnormal_larynx_morphology | 1.33372756 |
67 | * MP0002080_prenatal_lethality | 1.32960016 |
68 | MP0002735_abnormal_chemical_nociception | 1.32581683 |
69 | MP0000733_abnormal_muscle_development | 1.31536785 |
70 | MP0003861_abnormal_nervous_system | 1.31127988 |
71 | * MP0002085_abnormal_embryonic_tissue | 1.30288674 |
72 | MP0005023_abnormal_wound_healing | 1.28943265 |
73 | MP0003705_abnormal_hypodermis_morpholog | 1.27071135 |
74 | MP0003787_abnormal_imprinting | 1.25447140 |
75 | MP0001970_abnormal_pain_threshold | 1.25122791 |
76 | MP0000955_abnormal_spinal_cord | 1.24753784 |
77 | * MP0005380_embryogenesis_phenotype | 1.24364700 |
78 | * MP0001672_abnormal_embryogenesis/_devel | 1.24364700 |
79 | MP0005621_abnormal_cell_physiology | 1.23736911 |
80 | MP0005499_abnormal_olfactory_system | 1.23373908 |
81 | MP0005394_taste/olfaction_phenotype | 1.23373908 |
82 | MP0005058_abnormal_lysosome_morphology | 1.21597763 |
83 | MP0001346_abnormal_lacrimal_gland | 1.20522285 |
84 | MP0002152_abnormal_brain_morphology | 1.19063217 |
85 | MP0009840_abnormal_foam_cell | 1.18686653 |
86 | MP0002822_catalepsy | 1.16515485 |
87 | MP0003329_amyloid_beta_deposits | 1.15823721 |
88 | MP0010307_abnormal_tumor_latency | 1.14701186 |
89 | MP0009780_abnormal_chondrocyte_physiolo | 1.13425957 |
90 | MP0004133_heterotaxia | 1.12907491 |
91 | MP0010030_abnormal_orbit_morphology | 1.12212261 |
92 | MP0000467_abnormal_esophagus_morphology | 1.11856394 |
93 | MP0005375_adipose_tissue_phenotype | 1.11224950 |
94 | MP0000778_abnormal_nervous_system | 1.11040085 |
95 | MP0009672_abnormal_birth_weight | 1.10554495 |
96 | MP0008961_abnormal_basal_metabolism | 1.07441751 |
97 | MP0000751_myopathy | 1.06718188 |
98 | MP0000013_abnormal_adipose_tissue | 1.06188317 |
99 | MP0003984_embryonic_growth_retardation | 1.05123806 |
100 | MP0004924_abnormal_behavior | 1.05005063 |
101 | MP0005386_behavior/neurological_phenoty | 1.05005063 |
102 | MP0008770_decreased_survivor_rate | 1.04645164 |
103 | MP0008058_abnormal_DNA_repair | 1.04452622 |
104 | MP0000762_abnormal_tongue_morphology | 1.04385223 |
105 | MP0002272_abnormal_nervous_system | 1.04358369 |
106 | MP0002751_abnormal_autonomic_nervous | 1.04345857 |
107 | MP0003941_abnormal_skin_development | 1.04171524 |
108 | MP0002088_abnormal_embryonic_growth/wei | 1.04027720 |
109 | MP0000566_synostosis | 1.02974941 |
110 | MP0001216_abnormal_epidermal_layer | 1.02194544 |
111 | * MP0002086_abnormal_extraembryonic_tissu | 1.01951878 |
112 | MP0000534_abnormal_ureter_morphology | 0.99390715 |
113 | MP0002882_abnormal_neuron_morphology | 0.96812794 |
114 | MP0009278_abnormal_bone_marrow | 0.96248460 |
115 | MP0002557_abnormal_social/conspecific_i | 0.95391116 |
116 | MP0005623_abnormal_meninges_morphology | 0.94899293 |
117 | MP0004808_abnormal_hematopoietic_stem | 0.94107733 |
118 | MP0000358_abnormal_cell_content/ | 0.92182776 |
119 | MP0003315_abnormal_perineum_morphology | 0.91389920 |
120 | MP0005384_cellular_phenotype | 0.90712240 |
121 | MP0002066_abnormal_motor_capabilities/c | 0.90576013 |
122 | MP0005666_abnormal_adipose_tissue | 0.90084823 |
123 | MP0009703_decreased_birth_body | 0.90042618 |
124 | MP0002067_abnormal_sensory_capabilities | 0.89902942 |
125 | MP0005187_abnormal_penis_morphology | 0.89748148 |
126 | MP0003115_abnormal_respiratory_system | 0.87327250 |
127 | MP0006072_abnormal_retinal_apoptosis | 0.86741317 |
128 | MP0001348_abnormal_lacrimal_gland | 0.86679174 |
129 | MP0003385_abnormal_body_wall | 0.85906780 |
130 | MP0000858_altered_metastatic_potential | 0.82855181 |
131 | MP0010771_integument_phenotype | 0.82375522 |
132 | MP0005410_abnormal_fertilization | 0.82331096 |
133 | MP0003942_abnormal_urinary_system | 0.81697207 |
134 | MP0002234_abnormal_pharynx_morphology | 0.81310378 |
135 | MP0003950_abnormal_plasma_membrane | 0.81220737 |
136 | MP0001661_extended_life_span | 0.80215434 |
137 | MP0001486_abnormal_startle_reflex | 0.80124382 |
138 | MP0003279_aneurysm | 0.79802996 |
139 | MP0003698_abnormal_male_reproductive | 0.79211702 |
140 | MP0001849_ear_inflammation | 0.78706048 |
141 | MP0001243_abnormal_dermal_layer | 0.78463173 |
142 | MP0001299_abnormal_eye_distance/ | 0.77804798 |
143 | MP0000759_abnormal_skeletal_muscle | 0.77246572 |
144 | MP0002081_perinatal_lethality | 0.75957097 |
145 | MP0009053_abnormal_anal_canal | 0.75400938 |
146 | MP0000747_muscle_weakness | 0.75237314 |
147 | MP0003634_abnormal_glial_cell | 0.74603557 |
148 | MP0008789_abnormal_olfactory_epithelium | 0.74347719 |
149 | MP0004947_skin_inflammation | 0.74039016 |
150 | MP0001727_abnormal_embryo_implantation | 0.72982647 |
151 | MP0000428_abnormal_craniofacial_morphol | 0.72822432 |
152 | MP0008872_abnormal_physiological_respon | 0.72598084 |
153 | MP0009931_abnormal_skin_appearance | 0.72386191 |
154 | MP0002697_abnormal_eye_size | 0.71845948 |
155 | MP0000490_abnormal_crypts_of | 0.71790347 |
156 | MP0001915_intracranial_hemorrhage | 0.71424002 |
157 | MP0000313_abnormal_cell_death | 0.71240261 |
158 | MP0010368_abnormal_lymphatic_system | 0.67815618 |
159 | MP0003879_abnormal_hair_cell | 0.67079064 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Visual hallucinations (HP:0002367) | 4.18159163 |
2 | Myokymia (HP:0002411) | 3.96355727 |
3 | Abnormality of the lower motor neuron (HP:0002366) | 3.91072785 |
4 | Ependymoma (HP:0002888) | 3.64887653 |
5 | Premature rupture of membranes (HP:0001788) | 3.46079970 |
6 | Ulnar bowing (HP:0003031) | 3.33606832 |
7 | Abnormality of the labia minora (HP:0012880) | 3.32424511 |
8 | Insomnia (HP:0100785) | 3.21654004 |
9 | Distal lower limb amyotrophy (HP:0008944) | 3.13893362 |
10 | Protrusio acetabuli (HP:0003179) | 3.10959680 |
11 | Abnormality of the astrocytes (HP:0100707) | 3.09012295 |
12 | Astrocytoma (HP:0009592) | 3.09012295 |
13 | Focal seizures (HP:0007359) | 2.92289448 |
14 | Amyotrophic lateral sclerosis (HP:0007354) | 2.91920484 |
15 | Broad face (HP:0000283) | 2.86672671 |
16 | Focal motor seizures (HP:0011153) | 2.84771309 |
17 | Hyperacusis (HP:0010780) | 2.78766062 |
18 | Shoulder girdle muscle weakness (HP:0003547) | 2.76108071 |
19 | Abnormality of the Achilles tendon (HP:0005109) | 2.75747989 |
20 | Lower limb amyotrophy (HP:0007210) | 2.69210832 |
21 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.64236645 |
22 | Shallow orbits (HP:0000586) | 2.63796806 |
23 | Adenoma sebaceum (HP:0009720) | 2.63234559 |
24 | Angiofibromas (HP:0010615) | 2.63234559 |
25 | Pointed chin (HP:0000307) | 2.62951273 |
26 | Long palpebral fissure (HP:0000637) | 2.55142243 |
27 | Obstructive sleep apnea (HP:0002870) | 2.52607509 |
28 | Resting tremor (HP:0002322) | 2.51023779 |
29 | Renal duplication (HP:0000075) | 2.48699386 |
30 | Spinal rigidity (HP:0003306) | 2.43831704 |
31 | Papilledema (HP:0001085) | 2.40795912 |
32 | Short nail (HP:0001799) | 2.40320398 |
33 | Ankyloglossia (HP:0010296) | 2.39364149 |
34 | Absence seizures (HP:0002121) | 2.37895192 |
35 | Difficulty climbing stairs (HP:0003551) | 2.37637630 |
36 | Increased connective tissue (HP:0009025) | 2.37539283 |
37 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.35812795 |
38 | Increased nuchal translucency (HP:0010880) | 2.35228818 |
39 | Pelvic girdle muscle weakness (HP:0003749) | 2.34706638 |
40 | Disproportionate tall stature (HP:0001519) | 2.34468506 |
41 | Vertebral compression fractures (HP:0002953) | 2.33642423 |
42 | Trismus (HP:0000211) | 2.31729443 |
43 | Abnormality of the anterior horn cell (HP:0006802) | 2.31094345 |
44 | Degeneration of anterior horn cells (HP:0002398) | 2.31094345 |
45 | Stridor (HP:0010307) | 2.27859557 |
46 | Glioma (HP:0009733) | 2.26724834 |
47 | Fragile skin (HP:0001030) | 2.26564297 |
48 | Colon cancer (HP:0003003) | 2.25941134 |
49 | Urinary urgency (HP:0000012) | 2.24916533 |
50 | Ankle contracture (HP:0006466) | 2.24135711 |
51 | Atrophic scars (HP:0001075) | 2.24122488 |
52 | Delusions (HP:0000746) | 2.19972236 |
53 | Limb dystonia (HP:0002451) | 2.19466005 |
54 | Termporal pattern (HP:0011008) | 2.19289107 |
55 | Insidious onset (HP:0003587) | 2.19289107 |
56 | Carpal bone hypoplasia (HP:0001498) | 2.17005660 |
57 | Cerebral hypomyelination (HP:0006808) | 2.16776052 |
58 | Orthostatic hypotension (HP:0001278) | 2.15807844 |
59 | Impaired smooth pursuit (HP:0007772) | 2.14707061 |
60 | Deep palmar crease (HP:0006191) | 2.13446134 |
61 | Cerebral aneurysm (HP:0004944) | 2.13197083 |
62 | Distal lower limb muscle weakness (HP:0009053) | 2.11442821 |
63 | Progressive muscle weakness (HP:0003323) | 2.10286098 |
64 | Dysmetric saccades (HP:0000641) | 2.09908994 |
65 | Elfin facies (HP:0004428) | 2.05869208 |
66 | Abnormality of oral frenula (HP:0000190) | 2.05838968 |
67 | Dialeptic seizures (HP:0011146) | 2.05797948 |
68 | Medulloblastoma (HP:0002885) | 2.05140330 |
69 | Bowel diverticulosis (HP:0005222) | 2.04670115 |
70 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.03187692 |
71 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.03187692 |
72 | Amblyopia (HP:0000646) | 2.02483711 |
73 | Overriding aorta (HP:0002623) | 2.01356952 |
74 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.00925302 |
75 | Turricephaly (HP:0000262) | 2.00604141 |
76 | Broad distal phalanx of finger (HP:0009836) | 2.00584909 |
77 | Natal tooth (HP:0000695) | 1.99636117 |
78 | Basal cell carcinoma (HP:0002671) | 1.99490414 |
79 | Hand muscle atrophy (HP:0009130) | 1.99305647 |
80 | Deviation of the thumb (HP:0009603) | 1.98593126 |
81 | Megalocornea (HP:0000485) | 1.97547912 |
82 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.96934456 |
83 | Missing ribs (HP:0000921) | 1.96396271 |
84 | Elbow flexion contracture (HP:0002987) | 1.96194794 |
85 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.96090693 |
86 | Selective tooth agenesis (HP:0001592) | 1.94825985 |
87 | Depression (HP:0000716) | 1.93211868 |
88 | Patellar dislocation (HP:0002999) | 1.92139981 |
89 | Rhabdomyosarcoma (HP:0002859) | 1.90775020 |
90 | Mitral regurgitation (HP:0001653) | 1.90648780 |
91 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.90345642 |
92 | Advanced eruption of teeth (HP:0006288) | 1.89410808 |
93 | Urethral obstruction (HP:0000796) | 1.89220332 |
94 | Ankle clonus (HP:0011448) | 1.89119836 |
95 | Neoplasm of striated muscle (HP:0009728) | 1.87164347 |
96 | Renovascular hypertension (HP:0100817) | 1.87015439 |
97 | Hypercortisolism (HP:0001578) | 1.86947264 |
98 | Proximal placement of thumb (HP:0009623) | 1.86553537 |
99 | Abnormality of the motor neurons (HP:0002450) | 1.86209859 |
100 | Abnormal neuron morphology (HP:0012757) | 1.86209859 |
101 | Generalized amyotrophy (HP:0003700) | 1.85649581 |
102 | Arnold-Chiari malformation (HP:0002308) | 1.85271213 |
103 | Biconcave vertebral bodies (HP:0004586) | 1.85105515 |
104 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.85055346 |
105 | Cholecystitis (HP:0001082) | 1.83461375 |
106 | Abnormal gallbladder physiology (HP:0012438) | 1.83461375 |
107 | Dysautonomia (HP:0002459) | 1.83417799 |
108 | Intestinal polyp (HP:0005266) | 1.83369794 |
109 | Intestinal polyposis (HP:0200008) | 1.82622191 |
110 | Abnormal number of incisors (HP:0011064) | 1.82330742 |
111 | Sacral dimple (HP:0000960) | 1.80511442 |
112 | Heterotopia (HP:0002282) | 1.80414471 |
113 | Cerebral inclusion bodies (HP:0100314) | 1.80108787 |
114 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.79042819 |
115 | Bladder diverticulum (HP:0000015) | 1.78871997 |
116 | Back pain (HP:0003418) | 1.78182448 |
117 | Failure to thrive in infancy (HP:0001531) | 1.77993213 |
118 | Wormian bones (HP:0002645) | 1.77987288 |
119 | Primitive neuroectodermal tumor (HP:0030065) | 1.77476384 |
120 | Neuroblastic tumors (HP:0004376) | 1.77476384 |
121 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.77476384 |
122 | Neuroblastoma (HP:0003006) | 1.77476384 |
123 | Genu recurvatum (HP:0002816) | 1.77283403 |
124 | Impulsivity (HP:0100710) | 1.77251566 |
125 | Supranuclear gaze palsy (HP:0000605) | 1.77203331 |
126 | Poor eye contact (HP:0000817) | 1.76726722 |
127 | Spinal cord compression (HP:0002176) | 1.75497332 |
128 | Hyperthyroidism (HP:0000836) | 1.75344174 |
129 | Impaired pain sensation (HP:0007328) | 1.74918066 |
130 | Abnormality of pain sensation (HP:0010832) | 1.74918066 |
131 | Glossoptosis (HP:0000162) | 1.74026975 |
132 | Bradykinesia (HP:0002067) | 1.73717982 |
133 | Upper limb amyotrophy (HP:0009129) | 1.73486352 |
134 | Distal upper limb amyotrophy (HP:0007149) | 1.73486352 |
135 | Bowing of the arm (HP:0006488) | 1.72228565 |
136 | Bowed forearm bones (HP:0003956) | 1.72228565 |
137 | Generalized tonic-clonic seizures (HP:0002069) | 1.71996438 |
138 | Flattened epiphyses (HP:0003071) | 1.71537297 |
139 | Sparse lateral eyebrow (HP:0005338) | 1.70487020 |
140 | Attention deficit hyperactivity disorder (HP:0007018) | 1.70439967 |
141 | Fibroma (HP:0010614) | 1.70330205 |
142 | Rapidly progressive (HP:0003678) | 1.70159540 |
143 | Hypopigmentation of the fundus (HP:0007894) | 1.69650454 |
144 | Distal sensory impairment (HP:0002936) | 1.69166918 |
145 | Flat acetabular roof (HP:0003180) | 1.69155020 |
146 | Abnormality of the umbilical cord (HP:0010881) | 1.68854542 |
147 | Achilles tendon contracture (HP:0001771) | 1.68294383 |
148 | Cervical subluxation (HP:0003308) | 1.68292296 |
149 | Atonic seizures (HP:0010819) | 1.68143298 |
150 | Osteolytic defects of the hand bones (HP:0009699) | 1.68028771 |
151 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.68028771 |
152 | Neoplasm of the heart (HP:0100544) | 1.67526515 |
153 | Truncal ataxia (HP:0002078) | 1.67120459 |
154 | Personality changes (HP:0000751) | 1.66911353 |
155 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.66873005 |
156 | Dislocated radial head (HP:0003083) | 1.66368953 |
157 | Abnormal social behavior (HP:0012433) | 1.66198591 |
158 | Impaired social interactions (HP:0000735) | 1.66198591 |
159 | Truncus arteriosus (HP:0001660) | 1.65951468 |
160 | Abnormality of the salivary glands (HP:0010286) | 1.65850554 |
161 | Premature skin wrinkling (HP:0100678) | 1.65059016 |
162 | Abnormal ossification of hand bones (HP:0005921) | 1.64806854 |
163 | Annular pancreas (HP:0001734) | 1.64562611 |
164 | Flared metaphyses (HP:0003015) | 1.62645436 |
165 | Upper limb muscle weakness (HP:0003484) | 1.62595335 |
166 | Progressive hearing impairment (HP:0001730) | 1.62197840 |
167 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.61675942 |
168 | Hyperparathyroidism (HP:0000843) | 1.60490744 |
169 | Asymmetry of the thorax (HP:0001555) | 1.59780240 |
170 | Breast hypoplasia (HP:0003187) | 1.59195820 |
171 | Insulin resistance (HP:0000855) | 1.58955069 |
172 | Blue sclerae (HP:0000592) | 1.57951860 |
173 | Precocious puberty (HP:0000826) | 1.57461054 |
174 | Abnormality of the calcaneus (HP:0008364) | 1.56570211 |
175 | Acanthosis nigricans (HP:0000956) | 1.55939355 |
176 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.55773084 |
177 | Absent epiphyses (HP:0010577) | 1.55773084 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SMG1 | 4.09792952 |
2 | BUB1 | 3.15908512 |
3 | MAP3K9 | 3.11427160 |
4 | CDC7 | 2.94395227 |
5 | NEK1 | 2.88065901 |
6 | IRAK3 | 2.59566426 |
7 | PNCK | 2.47069884 |
8 | PRPF4B | 2.46200114 |
9 | WEE1 | 2.35604135 |
10 | LATS2 | 2.24511360 |
11 | SIK1 | 2.22703053 |
12 | MINK1 | 2.18618390 |
13 | NTRK3 | 2.15828184 |
14 | NME2 | 2.15649090 |
15 | EEF2K | 2.12479376 |
16 | MARK1 | 2.06750287 |
17 | TSSK6 | 2.03490891 |
18 | SCYL2 | 1.96923257 |
19 | PRKD3 | 1.93597605 |
20 | MST1R | 1.92768313 |
21 | NEK2 | 1.92369949 |
22 | KSR2 | 1.86397424 |
23 | TTN | 1.85347394 |
24 | PKN2 | 1.76828289 |
25 | ALK | 1.71464721 |
26 | RIPK1 | 1.63994178 |
27 | UHMK1 | 1.61495100 |
28 | BRSK1 | 1.58875715 |
29 | MAP3K4 | 1.56359076 |
30 | TESK1 | 1.55676641 |
31 | PAK6 | 1.54962117 |
32 | TRIB3 | 1.52938331 |
33 | PASK | 1.49386481 |
34 | TTK | 1.46297013 |
35 | KSR1 | 1.42500185 |
36 | PTK2 | 1.42198384 |
37 | PLK3 | 1.34731924 |
38 | MAP3K10 | 1.34499865 |
39 | TESK2 | 1.33141855 |
40 | NTRK1 | 1.32816589 |
41 | CDK12 | 1.32213665 |
42 | AURKA | 1.29872133 |
43 | TYRO3 | 1.29049666 |
44 | PLK1 | 1.27249326 |
45 | NTRK2 | 1.26367694 |
46 | LIMK1 | 1.23810790 |
47 | ICK | 1.19618180 |
48 | DAPK1 | 1.19041503 |
49 | CDK14 | 1.18679272 |
50 | CDK18 | 1.18291582 |
51 | CDK15 | 1.17762335 |
52 | FGFR4 | 1.15585673 |
53 | TAOK2 | 1.09196975 |
54 | CDK11A | 1.08355405 |
55 | ERN1 | 1.04875582 |
56 | SIK2 | 1.02483104 |
57 | MAP3K8 | 1.00024287 |
58 | MET | 0.96450128 |
59 | LMTK2 | 0.95021084 |
60 | EPHA2 | 0.94739943 |
61 | TLK1 | 0.94039016 |
62 | CAMKK1 | 0.93682841 |
63 | CHEK1 | 0.90370012 |
64 | GRK5 | 0.88811218 |
65 | RPS6KB2 | 0.87842571 |
66 | CCNB1 | 0.87660283 |
67 | DAPK2 | 0.85940050 |
68 | PLK2 | 0.84254712 |
69 | PAK2 | 0.82470418 |
70 | CHEK2 | 0.82290182 |
71 | TAOK1 | 0.81959107 |
72 | RPS6KA2 | 0.81614667 |
73 | CSNK1E | 0.80968057 |
74 | MAP3K13 | 0.80565906 |
75 | EPHA4 | 0.80201516 |
76 | MAP3K2 | 0.80077406 |
77 | AURKB | 0.79279064 |
78 | PDPK1 | 0.77971776 |
79 | GRK6 | 0.76701573 |
80 | PDK3 | 0.74076691 |
81 | PDK4 | 0.74076691 |
82 | CAMK1D | 0.73895216 |
83 | MAPK11 | 0.73750874 |
84 | CAMK1G | 0.73422844 |
85 | STK38 | 0.72133412 |
86 | CDK5 | 0.71680314 |
87 | RET | 0.71613556 |
88 | * CDK2 | 0.71121399 |
89 | EIF2AK1 | 0.70836276 |
90 | MAP2K4 | 0.70242411 |
91 | MAP2K3 | 0.70145366 |
92 | PTK6 | 0.69274695 |
93 | BRSK2 | 0.69187482 |
94 | CDK8 | 0.69177047 |
95 | CDK4 | 0.67288899 |
96 | MARK2 | 0.67279454 |
97 | DDR2 | 0.65840554 |
98 | PDGFRA | 0.64928932 |
99 | PRKCG | 0.64572239 |
100 | ATR | 0.63875686 |
101 | PIM2 | 0.63818528 |
102 | PRKD2 | 0.61748270 |
103 | IRAK2 | 0.61531953 |
104 | PAK1 | 0.60866137 |
105 | BRD4 | 0.60094211 |
106 | CDK7 | 0.59745001 |
107 | MTOR | 0.58766226 |
108 | MAP3K12 | 0.58719036 |
109 | VRK2 | 0.58423202 |
110 | MAP3K11 | 0.58134021 |
111 | MAP3K1 | 0.56838588 |
112 | SRPK1 | 0.56793185 |
113 | * CDK1 | 0.56646865 |
114 | ARAF | 0.53576776 |
115 | PRKCI | 0.53422507 |
116 | BRAF | 0.52634566 |
117 | PAK4 | 0.51999594 |
118 | CSNK1G2 | 0.50758623 |
119 | PRKG2 | 0.49780732 |
120 | FGFR1 | 0.49634331 |
121 | PBK | 0.49470803 |
122 | ILK | 0.49288253 |
123 | CDK9 | 0.47892430 |
124 | STK11 | 0.47214370 |
125 | RPS6KL1 | 0.47155259 |
126 | RPS6KC1 | 0.47155259 |
127 | BMX | 0.46332662 |
128 | CDK6 | 0.46047164 |
129 | CSNK2A2 | 0.45798400 |
130 | CDC42BPA | 0.45734191 |
131 | MAP2K2 | 0.45102770 |
132 | AKT2 | 0.44811646 |
133 | STK10 | 0.44727613 |
134 | MAP3K3 | 0.43561190 |
135 | ATM | 0.42776609 |
136 | DAPK3 | 0.42105891 |
137 | CSNK1G3 | 0.41445661 |
138 | PAK3 | 0.41310678 |
139 | MAPK10 | 0.40370037 |
140 | NME1 | 0.39755060 |
141 | FER | 0.38851891 |
142 | ERBB4 | 0.38482377 |
143 | RAF1 | 0.37752935 |
144 | LRRK2 | 0.37586525 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.64265071 |
2 | DNA replication_Homo sapiens_hsa03030 | 2.57374470 |
3 | * RNA transport_Homo sapiens_hsa03013 | 2.42025010 |
4 | Oocyte meiosis_Homo sapiens_hsa04114 | 2.33061966 |
5 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.31760067 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 2.28990983 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.17805747 |
8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.15813980 |
9 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.15727422 |
10 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.88220782 |
11 | Cell cycle_Homo sapiens_hsa04110 | 1.85667036 |
12 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.85061907 |
13 | Long-term potentiation_Homo sapiens_hsa04720 | 1.81842362 |
14 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.80439998 |
15 | Nicotine addiction_Homo sapiens_hsa05033 | 1.70381197 |
16 | Sulfur relay system_Homo sapiens_hsa04122 | 1.64690461 |
17 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.64470003 |
18 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.61216385 |
19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.55617595 |
20 | Alcoholism_Homo sapiens_hsa05034 | 1.50361823 |
21 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.50330238 |
22 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.48011400 |
23 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.46476499 |
24 | Olfactory transduction_Homo sapiens_hsa04740 | 1.42562065 |
25 | Gap junction_Homo sapiens_hsa04540 | 1.35617476 |
26 | Glioma_Homo sapiens_hsa05214 | 1.34594745 |
27 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.34485462 |
28 | Base excision repair_Homo sapiens_hsa03410 | 1.34460669 |
29 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.33382542 |
30 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.30251377 |
31 | Ribosome_Homo sapiens_hsa03010 | 1.30209477 |
32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.30126563 |
33 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.27226824 |
34 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.26409081 |
35 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.24553079 |
36 | GABAergic synapse_Homo sapiens_hsa04727 | 1.22996145 |
37 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.22848191 |
38 | Cocaine addiction_Homo sapiens_hsa05030 | 1.22775642 |
39 | Proteasome_Homo sapiens_hsa03050 | 1.22121134 |
40 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.21637610 |
41 | Insulin secretion_Homo sapiens_hsa04911 | 1.20432777 |
42 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.15098323 |
43 | Focal adhesion_Homo sapiens_hsa04510 | 1.15012525 |
44 | Circadian entrainment_Homo sapiens_hsa04713 | 1.13031978 |
45 | Thyroid cancer_Homo sapiens_hsa05216 | 1.11963485 |
46 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.11341021 |
47 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.08224043 |
48 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.07001553 |
49 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.05660934 |
50 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.03870787 |
51 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.01963872 |
52 | Adherens junction_Homo sapiens_hsa04520 | 1.00776560 |
53 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.98712795 |
54 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.98618916 |
55 | Lysine degradation_Homo sapiens_hsa00310 | 0.97208199 |
56 | Carbon metabolism_Homo sapiens_hsa01200 | 0.95755944 |
57 | Morphine addiction_Homo sapiens_hsa05032 | 0.95473735 |
58 | Colorectal cancer_Homo sapiens_hsa05210 | 0.95419750 |
59 | Melanogenesis_Homo sapiens_hsa04916 | 0.94049028 |
60 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.93262479 |
61 | Galactose metabolism_Homo sapiens_hsa00052 | 0.92584050 |
62 | Endometrial cancer_Homo sapiens_hsa05213 | 0.92311808 |
63 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.91825253 |
64 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.88242402 |
65 | Bladder cancer_Homo sapiens_hsa05219 | 0.87612490 |
66 | Prostate cancer_Homo sapiens_hsa05215 | 0.87344757 |
67 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.86886004 |
68 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.86264246 |
69 | Long-term depression_Homo sapiens_hsa04730 | 0.85443618 |
70 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.85424253 |
71 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.85173433 |
72 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.84249356 |
73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.84092150 |
74 | RNA polymerase_Homo sapiens_hsa03020 | 0.83674268 |
75 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.82022211 |
76 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.81919797 |
77 | Other glycan degradation_Homo sapiens_hsa00511 | 0.81732568 |
78 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.81268790 |
79 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.80780401 |
80 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.80734874 |
81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.80525888 |
82 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.80213363 |
83 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.79947529 |
84 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.79907427 |
85 | Apoptosis_Homo sapiens_hsa04210 | 0.79682302 |
86 | Endocytosis_Homo sapiens_hsa04144 | 0.79592607 |
87 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.79106562 |
88 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.79099170 |
89 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.79045569 |
90 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.78093336 |
91 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.78030936 |
92 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.75739500 |
93 | Salivary secretion_Homo sapiens_hsa04970 | 0.75107435 |
94 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.73352597 |
95 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.72206947 |
96 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.71674770 |
97 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.71036788 |
98 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.70968093 |
99 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.70724823 |
100 | Shigellosis_Homo sapiens_hsa05131 | 0.70355447 |
101 | HTLV-I infection_Homo sapiens_hsa05166 | 0.70283518 |
102 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.70152989 |
103 | Homologous recombination_Homo sapiens_hsa03440 | 0.69539965 |
104 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.69235867 |
105 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.68492561 |
106 | Hepatitis B_Homo sapiens_hsa05161 | 0.68199036 |
107 | Taste transduction_Homo sapiens_hsa04742 | 0.68030385 |
108 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.64160680 |
109 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.63180145 |
110 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.62974916 |
111 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.62507960 |
112 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.62002363 |
113 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.61444301 |
114 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.60804547 |
115 | Melanoma_Homo sapiens_hsa05218 | 0.60275092 |
116 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.60113507 |
117 | Renin secretion_Homo sapiens_hsa04924 | 0.59764054 |
118 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.58773799 |
119 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.58208527 |
120 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.57521616 |
121 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.56846695 |
122 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.56802401 |
123 | Axon guidance_Homo sapiens_hsa04360 | 0.56777907 |
124 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.56357746 |
125 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.56355524 |
126 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.56180494 |
127 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.54825379 |
128 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.54518567 |
129 | RNA degradation_Homo sapiens_hsa03018 | 0.53534148 |
130 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.53394957 |
131 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.53297482 |
132 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.53242071 |
133 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52726676 |
134 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.52645749 |
135 | Prion diseases_Homo sapiens_hsa05020 | 0.50950591 |
136 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.50622347 |
137 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.50585746 |
138 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.49809174 |
139 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.49746483 |
140 | Tight junction_Homo sapiens_hsa04530 | 0.49126894 |
141 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.48915082 |
142 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.46987477 |