

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 6.64325630 |
| 2 | proteasome assembly (GO:0043248) | 6.01676487 |
| 3 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 5.48558577 |
| 4 | regulation of immunoglobulin secretion (GO:0051023) | 5.42004199 |
| 5 | positive regulation of interleukin-17 production (GO:0032740) | 4.81260385 |
| 6 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.57258436 |
| 7 | negative regulation of dendrite development (GO:2000171) | 4.51382027 |
| 8 | negative regulation of B cell apoptotic process (GO:0002903) | 4.48224534 |
| 9 | transcription from mitochondrial promoter (GO:0006390) | 4.48184773 |
| 10 | regulation of collateral sprouting (GO:0048670) | 4.47718942 |
| 11 | regulation of regulatory T cell differentiation (GO:0045589) | 4.47455853 |
| 12 | DNA deamination (GO:0045006) | 4.45106022 |
| 13 | DNA double-strand break processing (GO:0000729) | 4.13540155 |
| 14 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 4.05907308 |
| 15 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 4.05907308 |
| 16 | isotype switching (GO:0045190) | 4.05907308 |
| 17 | maturation of 5.8S rRNA (GO:0000460) | 3.99549080 |
| 18 | proline transport (GO:0015824) | 3.95118286 |
| 19 | DNA damage response, detection of DNA damage (GO:0042769) | 3.86908248 |
| 20 | inositol phosphate catabolic process (GO:0071545) | 3.83220502 |
| 21 | positive regulation of isotype switching (GO:0045830) | 3.76157464 |
| 22 | negative regulation of protein oligomerization (GO:0032460) | 3.68539337 |
| 23 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.65602202 |
| 24 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.65602202 |
| 25 | GTP biosynthetic process (GO:0006183) | 3.60477982 |
| 26 | inositol phosphate dephosphorylation (GO:0046855) | 3.59572351 |
| 27 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 3.59572351 |
| 28 | chemosensory behavior (GO:0007635) | 3.54568763 |
| 29 | rRNA catabolic process (GO:0016075) | 3.53403827 |
| 30 | peptidyl-histidine modification (GO:0018202) | 3.52537107 |
| 31 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.51816951 |
| 32 | regulation of B cell apoptotic process (GO:0002902) | 3.49524093 |
| 33 | positive regulation of protein homodimerization activity (GO:0090073) | 3.42209425 |
| 34 | UTP metabolic process (GO:0046051) | 3.39421960 |
| 35 | polyol catabolic process (GO:0046174) | 3.37193270 |
| 36 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.36086757 |
| 37 | rRNA modification (GO:0000154) | 3.35474299 |
| 38 | somatic diversification of immunoglobulins (GO:0016445) | 3.33656244 |
| 39 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.30929461 |
| 40 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.29846246 |
| 41 | necroptotic process (GO:0070266) | 3.28090544 |
| 42 | positive regulation of DNA recombination (GO:0045911) | 3.27959216 |
| 43 | positive regulation of cell fate commitment (GO:0010455) | 3.27640032 |
| 44 | positive regulation of B cell mediated immunity (GO:0002714) | 3.27116902 |
| 45 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.27116902 |
| 46 | regulation of chronic inflammatory response (GO:0002676) | 3.25494849 |
| 47 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 3.25052640 |
| 48 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.24898919 |
| 49 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.24753262 |
| 50 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.24753262 |
| 51 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.24753262 |
| 52 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.24036158 |
| 53 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.23457272 |
| 54 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.23457272 |
| 55 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.21881376 |
| 56 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.21835246 |
| 57 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 3.19291755 |
| 58 | UTP biosynthetic process (GO:0006228) | 3.18711233 |
| 59 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.16853180 |
| 60 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.16379348 |
| 61 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.16379348 |
| 62 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.16379348 |
| 63 | chaperone-mediated protein transport (GO:0072321) | 3.15454665 |
| 64 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.12162402 |
| 65 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.11489794 |
| 66 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.11419541 |
| 67 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.11419541 |
| 68 | rRNA methylation (GO:0031167) | 3.11244361 |
| 69 | positive regulation of defense response to virus by host (GO:0002230) | 3.11166085 |
| 70 | pyrimidine ribonucleotide metabolic process (GO:0009218) | 3.08788012 |
| 71 | C4-dicarboxylate transport (GO:0015740) | 3.05682439 |
| 72 | somatic diversification of immune receptors (GO:0002200) | 3.04279508 |
| 73 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.04089246 |
| 74 | UMP metabolic process (GO:0046049) | 3.04089246 |
| 75 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.04089246 |
| 76 | UMP biosynthetic process (GO:0006222) | 3.04089246 |
| 77 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.03514609 |
| 78 | mitochondrial RNA metabolic process (GO:0000959) | 3.03291463 |
| 79 | tRNA aminoacylation for protein translation (GO:0006418) | 3.03187872 |
| 80 | tRNA aminoacylation (GO:0043039) | 3.02581685 |
| 81 | amino acid activation (GO:0043038) | 3.02581685 |
| 82 | regulation of protein homooligomerization (GO:0032462) | 2.98636883 |
| 83 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.97154583 |
| 84 | somatic cell DNA recombination (GO:0016444) | 2.94903987 |
| 85 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.94903987 |
| 86 | protein-cofactor linkage (GO:0018065) | 2.93090441 |
| 87 | negative regulation of ligase activity (GO:0051352) | 2.92579942 |
| 88 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.92579942 |
| 89 | ribosome biogenesis (GO:0042254) | 2.92507277 |
| 90 | positive regulation of activated T cell proliferation (GO:0042104) | 2.88883953 |
| 91 | positive regulation of ligase activity (GO:0051351) | 2.88037341 |
| 92 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.87814729 |
| 93 | IMP biosynthetic process (GO:0006188) | 2.87539446 |
| 94 | rRNA processing (GO:0006364) | 2.86715596 |
| 95 | pseudouridine synthesis (GO:0001522) | 2.84108977 |
| 96 | CTP metabolic process (GO:0046036) | 2.84009117 |
| 97 | CTP biosynthetic process (GO:0006241) | 2.84009117 |
| 98 | negative regulation of T cell apoptotic process (GO:0070233) | 2.82321738 |
| 99 | protein complex biogenesis (GO:0070271) | 2.80805625 |
| 100 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.80159492 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.00439877 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.49843619 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.68194500 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.48448193 |
| 5 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.46514165 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.30536407 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.88078425 |
| 8 | EWS_26573619_Chip-Seq_HEK293_Human | 2.75057260 |
| 9 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.74614554 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.72294470 |
| 11 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.57119033 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.55761589 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.51316045 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.51106570 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.50571676 |
| 16 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.41016192 |
| 17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.33800704 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.15023947 |
| 19 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.08084533 |
| 20 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.04607549 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.02487436 |
| 22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.90339177 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.89253297 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.87778070 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.86119128 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.85188398 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.81988355 |
| 28 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.80655598 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.80386797 |
| 30 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.76945886 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.75510848 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.71924065 |
| 33 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.67373654 |
| 34 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67260419 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.66361324 |
| 36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.64948123 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.64374772 |
| 38 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.61389907 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.57130181 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.56309755 |
| 41 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54528328 |
| 42 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.53373084 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.52532393 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.45023043 |
| 45 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.42266564 |
| 46 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.42266564 |
| 47 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40970924 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.40950558 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.35429336 |
| 50 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.35005433 |
| 51 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.34059075 |
| 52 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33259710 |
| 53 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.32274389 |
| 54 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32130860 |
| 55 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.29292474 |
| 56 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.27028538 |
| 57 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.22707260 |
| 58 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.22603645 |
| 59 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.21214220 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21188451 |
| 61 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.20964208 |
| 62 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.19991800 |
| 63 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17911882 |
| 64 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.16823651 |
| 65 | GATA3_26560356_Chip-Seq_TH2_Human | 1.14758278 |
| 66 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.12189789 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.12172857 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.12172857 |
| 69 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.10130688 |
| 70 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.08899427 |
| 71 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.08143830 |
| 72 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.07560140 |
| 73 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.07438751 |
| 74 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.05394995 |
| 75 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.97893729 |
| 76 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.97476448 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.95766601 |
| 78 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.94937509 |
| 79 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94351547 |
| 80 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94159904 |
| 81 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.93900236 |
| 82 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.93839081 |
| 83 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.92631039 |
| 84 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.91908408 |
| 85 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.91611966 |
| 86 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.89735258 |
| 87 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.88701174 |
| 88 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.87797706 |
| 89 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.87559652 |
| 90 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.86132396 |
| 91 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.86132396 |
| 92 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85984039 |
| 93 | NCOR_22424771_ChIP-Seq_293T_Human | 0.85209050 |
| 94 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.83787173 |
| 95 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.83529553 |
| 96 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83399209 |
| 97 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.82589975 |
| 98 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.81972035 |
| 99 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.81169607 |
| 100 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.81159395 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001984_abnormal_olfaction | 5.27045952 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.93454132 |
| 3 | MP0000516_abnormal_urinary_system | 3.68437418 |
| 4 | MP0005367_renal/urinary_system_phenotyp | 3.68437418 |
| 5 | MP0003300_gastrointestinal_ulcer | 3.33672831 |
| 6 | MP0000465_gastrointestinal_hemorrhage | 2.69505006 |
| 7 | MP0008058_abnormal_DNA_repair | 2.66535475 |
| 8 | MP0003950_abnormal_plasma_membrane | 2.55693730 |
| 9 | MP0010094_abnormal_chromosome_stability | 2.28650776 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.25393070 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.23508797 |
| 12 | MP0008057_abnormal_DNA_replication | 2.23267824 |
| 13 | MP0001501_abnormal_sleep_pattern | 2.11831156 |
| 14 | MP0003693_abnormal_embryo_hatching | 1.96556189 |
| 15 | MP0003718_maternal_effect | 1.92617244 |
| 16 | MP0005410_abnormal_fertilization | 1.84289965 |
| 17 | MP0001661_extended_life_span | 1.80292599 |
| 18 | MP0004742_abnormal_vestibular_system | 1.79987331 |
| 19 | MP0001853_heart_inflammation | 1.78459752 |
| 20 | MP0010234_abnormal_vibrissa_follicle | 1.75645165 |
| 21 | MP0004885_abnormal_endolymph | 1.74895042 |
| 22 | MP0003786_premature_aging | 1.72555525 |
| 23 | MP0001529_abnormal_vocalization | 1.70351604 |
| 24 | MP0009053_abnormal_anal_canal | 1.63823648 |
| 25 | MP0004957_abnormal_blastocyst_morpholog | 1.61515876 |
| 26 | MP0000685_abnormal_immune_system | 1.60389069 |
| 27 | MP0002102_abnormal_ear_morphology | 1.51221358 |
| 28 | MP0000604_amyloidosis | 1.49578894 |
| 29 | MP0002006_tumorigenesis | 1.47534807 |
| 30 | MP0003656_abnormal_erythrocyte_physiolo | 1.44567964 |
| 31 | MP0002751_abnormal_autonomic_nervous | 1.42782407 |
| 32 | MP0005671_abnormal_response_to | 1.35979961 |
| 33 | MP0001968_abnormal_touch/_nociception | 1.33946632 |
| 34 | MP0003567_abnormal_fetal_cardiomyocyte | 1.33373284 |
| 35 | MP0001905_abnormal_dopamine_level | 1.32380621 |
| 36 | MP0003806_abnormal_nucleotide_metabolis | 1.31898887 |
| 37 | MP0001800_abnormal_humoral_immune | 1.31333808 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.28884560 |
| 39 | MP0000703_abnormal_thymus_morphology | 1.27114959 |
| 40 | MP0005387_immune_system_phenotype | 1.26730113 |
| 41 | MP0001790_abnormal_immune_system | 1.26730113 |
| 42 | MP0006072_abnormal_retinal_apoptosis | 1.26056130 |
| 43 | MP0000537_abnormal_urethra_morphology | 1.24456420 |
| 44 | MP0009745_abnormal_behavioral_response | 1.22776980 |
| 45 | MP0005379_endocrine/exocrine_gland_phen | 1.22289090 |
| 46 | MP0009785_altered_susceptibility_to | 1.22015131 |
| 47 | MP0000538_abnormal_urinary_bladder | 1.19430323 |
| 48 | MP0002148_abnormal_hypersensitivity_rea | 1.17884309 |
| 49 | MP0003077_abnormal_cell_cycle | 1.14551343 |
| 50 | MP0008007_abnormal_cellular_replicative | 1.13542401 |
| 51 | MP0002166_altered_tumor_susceptibility | 1.12605890 |
| 52 | MP0004270_analgesia | 1.09555439 |
| 53 | MP0001177_atelectasis | 1.04677328 |
| 54 | MP0002210_abnormal_sex_determination | 1.04453638 |
| 55 | MP0006292_abnormal_olfactory_placode | 1.02335161 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.01254783 |
| 57 | MP0002160_abnormal_reproductive_system | 1.00330961 |
| 58 | MP0005646_abnormal_pituitary_gland | 0.99838391 |
| 59 | MP0002272_abnormal_nervous_system | 0.99824400 |
| 60 | MP0002722_abnormal_immune_system | 0.97723009 |
| 61 | MP0008789_abnormal_olfactory_epithelium | 0.95913290 |
| 62 | MP0002736_abnormal_nociception_after | 0.95310234 |
| 63 | MP0002398_abnormal_bone_marrow | 0.93673735 |
| 64 | MP0005389_reproductive_system_phenotype | 0.90761183 |
| 65 | MP0005645_abnormal_hypothalamus_physiol | 0.89648851 |
| 66 | MP0001919_abnormal_reproductive_system | 0.87403256 |
| 67 | MP0006036_abnormal_mitochondrial_physio | 0.86587931 |
| 68 | MP0009333_abnormal_splenocyte_physiolog | 0.85051178 |
| 69 | MP0001929_abnormal_gametogenesis | 0.82099147 |
| 70 | MP0001764_abnormal_homeostasis | 0.81805742 |
| 71 | MP0008770_decreased_survivor_rate | 0.81424379 |
| 72 | MP0000427_abnormal_hair_cycle | 0.79901353 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.77925490 |
| 74 | MP0001119_abnormal_female_reproductive | 0.76984805 |
| 75 | MP0003633_abnormal_nervous_system | 0.76460385 |
| 76 | MP0001727_abnormal_embryo_implantation | 0.76391172 |
| 77 | MP0008932_abnormal_embryonic_tissue | 0.75436806 |
| 78 | MP0003698_abnormal_male_reproductive | 0.74844055 |
| 79 | MP0003186_abnormal_redox_activity | 0.74656174 |
| 80 | MP0010368_abnormal_lymphatic_system | 0.72644415 |
| 81 | MP0002429_abnormal_blood_cell | 0.72357851 |
| 82 | MP0002723_abnormal_immune_serum | 0.71132874 |
| 83 | MP0008872_abnormal_physiological_respon | 0.70736308 |
| 84 | MP0001486_abnormal_startle_reflex | 0.70282625 |
| 85 | MP0003878_abnormal_ear_physiology | 0.67768774 |
| 86 | MP0005377_hearing/vestibular/ear_phenot | 0.67768774 |
| 87 | MP0005332_abnormal_amino_acid | 0.67615544 |
| 88 | MP0005000_abnormal_immune_tolerance | 0.66504286 |
| 89 | MP0002452_abnormal_antigen_presenting | 0.65794623 |
| 90 | MP0009697_abnormal_copulation | 0.65765241 |
| 91 | MP0000372_irregular_coat_pigmentation | 0.65513744 |
| 92 | MP0002572_abnormal_emotion/affect_behav | 0.64799058 |
| 93 | MP0003936_abnormal_reproductive_system | 0.64645370 |
| 94 | MP0000716_abnormal_immune_system | 0.64556523 |
| 95 | MP0005075_abnormal_melanosome_morpholog | 0.64345705 |
| 96 | MP0005266_abnormal_metabolism | 0.63943258 |
| 97 | MP0002090_abnormal_vision | 0.63746381 |
| 98 | MP0002069_abnormal_eating/drinking_beha | 0.63392721 |
| 99 | MP0000653_abnormal_sex_gland | 0.63127857 |
| 100 | MP0010307_abnormal_tumor_latency | 0.62783471 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.12720306 |
| 2 | Increased IgM level (HP:0003496) | 4.88855212 |
| 3 | Lipid accumulation in hepatocytes (HP:0006561) | 3.87664570 |
| 4 | IgG deficiency (HP:0004315) | 3.85881816 |
| 5 | Neoplasm of the adrenal cortex (HP:0100641) | 3.70847966 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.54037162 |
| 7 | Type 2 muscle fiber atrophy (HP:0003554) | 3.51354630 |
| 8 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.37858698 |
| 9 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.26687239 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.26664289 |
| 11 | Renal cortical cysts (HP:0000803) | 3.18434414 |
| 12 | Muscle fiber atrophy (HP:0100295) | 3.15949338 |
| 13 | Abnormality of the labia minora (HP:0012880) | 3.10907174 |
| 14 | Abnormality of the renal cortex (HP:0011035) | 3.07416111 |
| 15 | Squamous cell carcinoma (HP:0002860) | 3.04981730 |
| 16 | Conjunctival hamartoma (HP:0100780) | 2.96498302 |
| 17 | IgA deficiency (HP:0002720) | 2.95749694 |
| 18 | Increased CSF lactate (HP:0002490) | 2.90534956 |
| 19 | 3-Methylglutaconic aciduria (HP:0003535) | 2.90313085 |
| 20 | Increased serum lactate (HP:0002151) | 2.84418141 |
| 21 | Dyschromatopsia (HP:0007641) | 2.82463765 |
| 22 | Abnormality of T cell physiology (HP:0011840) | 2.74959051 |
| 23 | Acute necrotizing encephalopathy (HP:0006965) | 2.70765519 |
| 24 | Neoplasm of the adrenal gland (HP:0100631) | 2.66751265 |
| 25 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.59296960 |
| 26 | Cutaneous melanoma (HP:0012056) | 2.56171300 |
| 27 | Nephronophthisis (HP:0000090) | 2.53962641 |
| 28 | Aqueductal stenosis (HP:0002410) | 2.53830502 |
| 29 | Thyroiditis (HP:0100646) | 2.51394830 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.51170694 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.51170694 |
| 32 | Chronic sinusitis (HP:0011109) | 2.50947099 |
| 33 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.49269572 |
| 34 | Mitochondrial inheritance (HP:0001427) | 2.49182733 |
| 35 | Progressive microcephaly (HP:0000253) | 2.47271096 |
| 36 | Duplicated collecting system (HP:0000081) | 2.40452900 |
| 37 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.38806036 |
| 38 | Renal Fanconi syndrome (HP:0001994) | 2.37383196 |
| 39 | Abolished electroretinogram (ERG) (HP:0000550) | 2.37085256 |
| 40 | Cerebral edema (HP:0002181) | 2.35662889 |
| 41 | Cone-rod dystrophy (HP:0000548) | 2.26596660 |
| 42 | Abnormality of B cell number (HP:0010975) | 2.26039686 |
| 43 | Absent thumb (HP:0009777) | 2.25992442 |
| 44 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.25876347 |
| 45 | Acute encephalopathy (HP:0006846) | 2.21632245 |
| 46 | Abnormality of the renal collecting system (HP:0004742) | 2.20172342 |
| 47 | B lymphocytopenia (HP:0010976) | 2.20001019 |
| 48 | Poor suck (HP:0002033) | 2.17546207 |
| 49 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.17329048 |
| 50 | Abnormality of the renal medulla (HP:0100957) | 2.16587196 |
| 51 | Abnormality of the pons (HP:0007361) | 2.12116251 |
| 52 | Adactyly (HP:0009776) | 2.11371338 |
| 53 | Poor head control (HP:0002421) | 2.11346697 |
| 54 | Abnormality of methionine metabolism (HP:0010901) | 2.10155219 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 2.08917830 |
| 56 | Hyperalaninemia (HP:0003348) | 2.08917830 |
| 57 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.08917830 |
| 58 | Poor speech (HP:0002465) | 2.08822137 |
| 59 | Optic disc pallor (HP:0000543) | 2.08695477 |
| 60 | Exertional dyspnea (HP:0002875) | 2.07926456 |
| 61 | Respiratory difficulties (HP:0002880) | 2.07566775 |
| 62 | Hamartoma of the eye (HP:0010568) | 2.06781323 |
| 63 | Increased muscle lipid content (HP:0009058) | 2.05207918 |
| 64 | Ureteral duplication (HP:0000073) | 2.04818787 |
| 65 | Abnormality of the nasal septum (HP:0000419) | 2.02802847 |
| 66 | Increased intramyocellular lipid droplets (HP:0012240) | 2.02754415 |
| 67 | Pancreatic cysts (HP:0001737) | 2.00816082 |
| 68 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.00203308 |
| 69 | Abnormality of T cells (HP:0002843) | 1.96045741 |
| 70 | Hypomagnesemia (HP:0002917) | 1.95547615 |
| 71 | Hepatocellular necrosis (HP:0001404) | 1.95325452 |
| 72 | Congenital, generalized hypertrichosis (HP:0004540) | 1.93804196 |
| 73 | Abnormal number of incisors (HP:0011064) | 1.92758830 |
| 74 | Pancytopenia (HP:0001876) | 1.91326559 |
| 75 | Cleft eyelid (HP:0000625) | 1.91304779 |
| 76 | Chronic hepatic failure (HP:0100626) | 1.91248896 |
| 77 | Amyotrophic lateral sclerosis (HP:0007354) | 1.90261567 |
| 78 | Meningioma (HP:0002858) | 1.87186565 |
| 79 | Pigmentary retinal degeneration (HP:0001146) | 1.86887012 |
| 80 | Respiratory failure (HP:0002878) | 1.86087888 |
| 81 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.84603015 |
| 82 | Meckel diverticulum (HP:0002245) | 1.82883951 |
| 83 | Macular degeneration (HP:0000608) | 1.82711315 |
| 84 | Polyuria (HP:0000103) | 1.81811904 |
| 85 | Lethargy (HP:0001254) | 1.81336216 |
| 86 | Basal cell carcinoma (HP:0002671) | 1.81009112 |
| 87 | Furrowed tongue (HP:0000221) | 1.80434067 |
| 88 | Vitreoretinal degeneration (HP:0000655) | 1.79479350 |
| 89 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.78338096 |
| 90 | Abnormality of the parathyroid morphology (HP:0011766) | 1.78118293 |
| 91 | Colon cancer (HP:0003003) | 1.77291972 |
| 92 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.76623274 |
| 93 | Neutropenia (HP:0001875) | 1.75421144 |
| 94 | Patellar aplasia (HP:0006443) | 1.75101658 |
| 95 | Amblyopia (HP:0000646) | 1.74728281 |
| 96 | Abnormality of the preputium (HP:0100587) | 1.74551796 |
| 97 | Exercise intolerance (HP:0003546) | 1.72958446 |
| 98 | Azoospermia (HP:0000027) | 1.72463481 |
| 99 | Abnormality of the ileum (HP:0001549) | 1.70533835 |
| 100 | Constricted visual fields (HP:0001133) | 1.69691515 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 7.28588532 |
| 2 | TSSK6 | 3.74956523 |
| 3 | FGFR2 | 3.53801943 |
| 4 | MST4 | 3.27897975 |
| 5 | WNK3 | 3.15552991 |
| 6 | EIF2AK1 | 2.81383266 |
| 7 | SRPK1 | 2.66469914 |
| 8 | TXK | 2.50707325 |
| 9 | EIF2AK3 | 2.46284098 |
| 10 | SCYL2 | 1.99552877 |
| 11 | PLK3 | 1.98399945 |
| 12 | TLK1 | 1.97550968 |
| 13 | BUB1 | 1.89742013 |
| 14 | ZAK | 1.89405107 |
| 15 | NEK1 | 1.83186837 |
| 16 | PLK4 | 1.72387866 |
| 17 | ADRBK2 | 1.66262293 |
| 18 | PINK1 | 1.65017365 |
| 19 | VRK2 | 1.61826127 |
| 20 | NME1 | 1.45325110 |
| 21 | KDR | 1.40410070 |
| 22 | STK39 | 1.29232958 |
| 23 | VRK1 | 1.23614887 |
| 24 | ALK | 1.23097822 |
| 25 | CCNB1 | 1.23007192 |
| 26 | PLK2 | 1.20979110 |
| 27 | TNIK | 1.20587439 |
| 28 | EIF2AK2 | 1.18250261 |
| 29 | PLK1 | 1.17672344 |
| 30 | FGFR3 | 1.17147614 |
| 31 | GRK1 | 1.16829154 |
| 32 | MAP4K1 | 1.11877571 |
| 33 | PAK4 | 1.09776772 |
| 34 | RPS6KA4 | 1.08955085 |
| 35 | MKNK2 | 1.07378289 |
| 36 | DYRK3 | 1.06611457 |
| 37 | TTK | 1.04700893 |
| 38 | NME2 | 1.02517580 |
| 39 | TAOK3 | 1.00171366 |
| 40 | ATR | 0.98566576 |
| 41 | NUAK1 | 0.96235189 |
| 42 | IKBKE | 0.93491541 |
| 43 | OXSR1 | 0.93293412 |
| 44 | CDK3 | 0.93048705 |
| 45 | MAP3K12 | 0.90561723 |
| 46 | IKBKB | 0.87865091 |
| 47 | TRIM28 | 0.87320612 |
| 48 | SIK3 | 0.85408832 |
| 49 | PHKG1 | 0.84455670 |
| 50 | PHKG2 | 0.84455670 |
| 51 | TEC | 0.76490353 |
| 52 | PASK | 0.71892104 |
| 53 | RPS6KA5 | 0.69499448 |
| 54 | WNK4 | 0.65848463 |
| 55 | BMPR2 | 0.65189180 |
| 56 | TAF1 | 0.62573589 |
| 57 | CHEK1 | 0.59861341 |
| 58 | BTK | 0.59737338 |
| 59 | MAP4K2 | 0.57208122 |
| 60 | DAPK1 | 0.52470880 |
| 61 | INSRR | 0.51933144 |
| 62 | PKN1 | 0.51807125 |
| 63 | MKNK1 | 0.51713350 |
| 64 | STK4 | 0.50021233 |
| 65 | ITK | 0.48134177 |
| 66 | CSNK1A1L | 0.46445863 |
| 67 | CDC7 | 0.46135960 |
| 68 | FGFR1 | 0.46076211 |
| 69 | ATM | 0.45063754 |
| 70 | MAP3K4 | 0.44368767 |
| 71 | AURKB | 0.41589764 |
| 72 | CSNK2A1 | 0.41039726 |
| 73 | WEE1 | 0.40752004 |
| 74 | MAP3K11 | 0.39681609 |
| 75 | CSNK2A2 | 0.39601086 |
| 76 | CAMK4 | 0.39580208 |
| 77 | DYRK2 | 0.37361881 |
| 78 | BCR | 0.36118560 |
| 79 | PTK2B | 0.35538173 |
| 80 | PAK3 | 0.35323928 |
| 81 | CSNK1G3 | 0.34899594 |
| 82 | LCK | 0.34110867 |
| 83 | PRKCE | 0.31994648 |
| 84 | PRKCZ | 0.31639964 |
| 85 | PRKCB | 0.31338018 |
| 86 | GRK7 | 0.30057839 |
| 87 | CSNK1G1 | 0.29777756 |
| 88 | CAMK2A | 0.29234428 |
| 89 | CSNK1A1 | 0.28987315 |
| 90 | TRPM7 | 0.27590936 |
| 91 | PRKCG | 0.26471943 |
| 92 | CDK1 | 0.26168220 |
| 93 | LYN | 0.24790030 |
| 94 | CAMK1 | 0.24420749 |
| 95 | CSNK1G2 | 0.24123628 |
| 96 | BCKDK | 0.23781068 |
| 97 | TAOK2 | 0.23055589 |
| 98 | SYK | 0.22979990 |
| 99 | PRKDC | 0.22894067 |
| 100 | CSNK1E | 0.22521684 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.92998960 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.06980740 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 2.91131011 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.68052097 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 2.54181731 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.47655703 |
| 7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.33128557 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.26551625 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.22624117 |
| 10 | Basal transcription factors_Homo sapiens_hsa03022 | 2.20981614 |
| 11 | RNA degradation_Homo sapiens_hsa03018 | 2.16022617 |
| 12 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.13138450 |
| 13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.11229183 |
| 14 | Protein export_Homo sapiens_hsa03060 | 2.00552664 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.99094074 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.92090599 |
| 17 | Parkinsons disease_Homo sapiens_hsa05012 | 1.79127856 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 1.78027476 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.76764478 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.75434344 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.75082463 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.67467645 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.64659543 |
| 24 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.58611931 |
| 25 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.57955766 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.56687672 |
| 27 | Base excision repair_Homo sapiens_hsa03410 | 1.52705485 |
| 28 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.45595450 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.42051976 |
| 30 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.35150247 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.33002443 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32013025 |
| 33 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.27502439 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.24255433 |
| 35 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.21529595 |
| 36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.21162215 |
| 37 | Huntingtons disease_Homo sapiens_hsa05016 | 1.20426037 |
| 38 | Ribosome_Homo sapiens_hsa03010 | 1.15273584 |
| 39 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.15271160 |
| 40 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.10616780 |
| 41 | Nicotine addiction_Homo sapiens_hsa05033 | 1.03080990 |
| 42 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01270467 |
| 43 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.00497678 |
| 44 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.95202602 |
| 45 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.95093001 |
| 46 | Taste transduction_Homo sapiens_hsa04742 | 0.94116549 |
| 47 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.91519893 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 0.89403416 |
| 49 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.87971760 |
| 50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.87289784 |
| 51 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.86308542 |
| 52 | Alzheimers disease_Homo sapiens_hsa05010 | 0.85436749 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.83580257 |
| 54 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.76730697 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.75362730 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.74976412 |
| 57 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.68574991 |
| 58 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.68266982 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.67883143 |
| 60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.63826536 |
| 61 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.61439573 |
| 62 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.59671795 |
| 63 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.58064573 |
| 64 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57982120 |
| 65 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.57970172 |
| 66 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.57355677 |
| 67 | Morphine addiction_Homo sapiens_hsa05032 | 0.55815199 |
| 68 | Measles_Homo sapiens_hsa05162 | 0.54844113 |
| 69 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.54524813 |
| 70 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52563128 |
| 71 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.50066211 |
| 72 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.49273344 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.48796189 |
| 74 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.46534029 |
| 75 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.46247157 |
| 76 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.45596022 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44564652 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42649300 |
| 79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42394160 |
| 80 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.40184642 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.37637009 |
| 82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37429958 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36217139 |
| 84 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.35000453 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.34950171 |
| 86 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.31892487 |
| 87 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.30390719 |
| 88 | HTLV-I infection_Homo sapiens_hsa05166 | 0.28940028 |
| 89 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.28311687 |
| 90 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.27967874 |
| 91 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.27424258 |
| 92 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27117843 |
| 93 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.26946778 |
| 94 | Cocaine addiction_Homo sapiens_hsa05030 | 0.24344901 |
| 95 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.23593057 |
| 96 | GABAergic synapse_Homo sapiens_hsa04727 | 0.23213161 |
| 97 | Circadian rhythm_Homo sapiens_hsa04710 | 0.22051959 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.20086476 |
| 99 | Legionellosis_Homo sapiens_hsa05134 | 0.19525836 |
| 100 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.19433359 |

