

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 8.54244126 |
| 2 | cytidine metabolic process (GO:0046087) | 8.34144292 |
| 3 | cytidine catabolic process (GO:0006216) | 8.34144292 |
| 4 | cytidine deamination (GO:0009972) | 8.34144292 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 8.01332784 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.19876970 |
| 7 | proteasome assembly (GO:0043248) | 4.98383357 |
| 8 | negative regulation by host of viral transcription (GO:0043922) | 4.54113801 |
| 9 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.51845911 |
| 10 | regulation of chronic inflammatory response (GO:0002676) | 4.49836363 |
| 11 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.48220682 |
| 12 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.41036021 |
| 13 | negative regulation of T cell apoptotic process (GO:0070233) | 4.38344620 |
| 14 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.30680660 |
| 15 | regulation of regulatory T cell differentiation (GO:0045589) | 4.26788949 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.19268123 |
| 17 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 4.17292845 |
| 18 | sequestering of actin monomers (GO:0042989) | 4.11957931 |
| 19 | negative regulation of ligase activity (GO:0051352) | 4.10571414 |
| 20 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.10571414 |
| 21 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.06815314 |
| 22 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.06815314 |
| 23 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.04971369 |
| 24 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.04971369 |
| 25 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.04971369 |
| 26 | positive T cell selection (GO:0043368) | 4.02440558 |
| 27 | actin nucleation (GO:0045010) | 4.01961590 |
| 28 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.01272448 |
| 29 | cytolysis (GO:0019835) | 3.98858613 |
| 30 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.97165102 |
| 31 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.93456544 |
| 32 | positive thymic T cell selection (GO:0045059) | 3.92905366 |
| 33 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.92584904 |
| 34 | ATP synthesis coupled proton transport (GO:0015986) | 3.92584904 |
| 35 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.89528841 |
| 36 | regulation of activation of Janus kinase activity (GO:0010533) | 3.86884367 |
| 37 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.86676613 |
| 38 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.85155675 |
| 39 | eosinophil chemotaxis (GO:0048245) | 3.83606244 |
| 40 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.83536517 |
| 41 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.83536517 |
| 42 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.80192256 |
| 43 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.75021231 |
| 44 | T cell migration (GO:0072678) | 3.72212429 |
| 45 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.72118783 |
| 46 | respiratory electron transport chain (GO:0022904) | 3.64779832 |
| 47 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.63915712 |
| 48 | negative regulation of viral genome replication (GO:0045071) | 3.63076156 |
| 49 | macrophage chemotaxis (GO:0048246) | 3.62292425 |
| 50 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.61700853 |
| 51 | electron transport chain (GO:0022900) | 3.58879733 |
| 52 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.57526105 |
| 53 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.56636906 |
| 54 | positive regulation of tolerance induction (GO:0002645) | 3.53144908 |
| 55 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.52925029 |
| 56 | protein neddylation (GO:0045116) | 3.49973991 |
| 57 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.49737801 |
| 58 | eosinophil migration (GO:0072677) | 3.48042720 |
| 59 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.46238405 |
| 60 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.43381334 |
| 61 | negative T cell selection (GO:0043383) | 3.43150696 |
| 62 | cellular response to interleukin-15 (GO:0071350) | 3.39378476 |
| 63 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.38918350 |
| 64 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.38918350 |
| 65 | negative regulation of stress fiber assembly (GO:0051497) | 3.36123032 |
| 66 | regulation of T cell tolerance induction (GO:0002664) | 3.34770561 |
| 67 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.32021466 |
| 68 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.30066549 |
| 69 | positive regulation of cell cycle arrest (GO:0071158) | 3.29501193 |
| 70 | positive regulation of ligase activity (GO:0051351) | 3.28474559 |
| 71 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.25087696 |
| 72 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.25055206 |
| 73 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.24530883 |
| 74 | positive regulation of cell killing (GO:0031343) | 3.24478056 |
| 75 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.20008601 |
| 76 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.20008601 |
| 77 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.13684743 |
| 78 | regulation of cellular amine metabolic process (GO:0033238) | 3.13209299 |
| 79 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.11691123 |
| 80 | iron-sulfur cluster assembly (GO:0016226) | 3.09878212 |
| 81 | metallo-sulfur cluster assembly (GO:0031163) | 3.09878212 |
| 82 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.09691842 |
| 83 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.07474738 |
| 84 | response to interferon-beta (GO:0035456) | 3.05768164 |
| 85 | thymic T cell selection (GO:0045061) | 3.01702124 |
| 86 | protein complex biogenesis (GO:0070271) | 3.00488522 |
| 87 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.00061540 |
| 88 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.99993838 |
| 89 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.98313485 |
| 90 | regulation of T cell apoptotic process (GO:0070232) | 2.94497781 |
| 91 | chaperone-mediated protein transport (GO:0072321) | 2.92849809 |
| 92 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.91157013 |
| 93 | regulation of viral genome replication (GO:0045069) | 2.89699646 |
| 94 | positive regulation of T cell apoptotic process (GO:0070234) | 2.88311099 |
| 95 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.88088305 |
| 96 | regulation of ligase activity (GO:0051340) | 2.87047229 |
| 97 | regulation of cell killing (GO:0031341) | 2.86369704 |
| 98 | positive regulation of lymphocyte migration (GO:2000403) | 2.84252475 |
| 99 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.83347337 |
| 100 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.82290437 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.24772694 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 5.09309138 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.27493784 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.68415286 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.56567296 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.45481804 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.34855411 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.28520448 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.20146354 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.06951700 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.66235455 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.65283995 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.56704823 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.55765630 |
| 15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.54953774 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.53907413 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.41188294 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.25930401 |
| 19 | MYB_26560356_Chip-Seq_TH2_Human | 2.17176089 |
| 20 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.16886681 |
| 21 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.09340637 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.06374098 |
| 23 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.02078167 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.99140236 |
| 25 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.97403919 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.94957800 |
| 27 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.92136980 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.82512697 |
| 29 | VDR_22108803_ChIP-Seq_LS180_Human | 1.71043714 |
| 30 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.67221769 |
| 31 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67124630 |
| 32 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.63208378 |
| 33 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.59171295 |
| 34 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.57743563 |
| 35 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.54857379 |
| 36 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.54329109 |
| 37 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.54122826 |
| 38 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.51476846 |
| 39 | GATA3_26560356_Chip-Seq_TH2_Human | 1.49971005 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.45276321 |
| 41 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.44990045 |
| 42 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42821065 |
| 43 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.41605017 |
| 44 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.36799968 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.35843670 |
| 46 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.35619332 |
| 47 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.34312207 |
| 48 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.32948836 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32299906 |
| 50 | MYB_26560356_Chip-Seq_TH1_Human | 1.32230831 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.30416263 |
| 52 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.27759546 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.25259073 |
| 54 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.23790476 |
| 55 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.23420339 |
| 56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.22764446 |
| 57 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.20590738 |
| 58 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.20136222 |
| 59 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16223607 |
| 60 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.13964119 |
| 61 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.13368253 |
| 62 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.13159689 |
| 63 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.10629726 |
| 64 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10554625 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.08810002 |
| 66 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.07934167 |
| 67 | UTX_26944678_Chip-Seq_JUKART_Human | 1.07739569 |
| 68 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.07118069 |
| 69 | MAF_26560356_Chip-Seq_TH2_Human | 1.05490475 |
| 70 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.05128228 |
| 71 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.02757803 |
| 72 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.02049889 |
| 73 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01191849 |
| 74 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.99836473 |
| 75 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.99039729 |
| 76 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.97149609 |
| 77 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.95879186 |
| 78 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.95488248 |
| 79 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.94948659 |
| 80 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.94861010 |
| 81 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.94709145 |
| 82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93640683 |
| 83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93640683 |
| 84 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.93482845 |
| 85 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.92743262 |
| 86 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.91687389 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.91330704 |
| 88 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90926102 |
| 89 | MAF_26560356_Chip-Seq_TH1_Human | 0.90744885 |
| 90 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.89420900 |
| 91 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.89378231 |
| 92 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.89266798 |
| 93 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89188528 |
| 94 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.87805882 |
| 95 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.87307788 |
| 96 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.86298092 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.85597318 |
| 98 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.84936089 |
| 99 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.84212498 |
| 100 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.83596958 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.10436422 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.56726084 |
| 3 | MP0003763_abnormal_thymus_physiology | 3.39306852 |
| 4 | MP0009785_altered_susceptibility_to | 3.35566836 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 3.01919738 |
| 6 | MP0004147_increased_porphyrin_level | 2.89900179 |
| 7 | MP0001873_stomach_inflammation | 2.83008430 |
| 8 | MP0003786_premature_aging | 2.65604935 |
| 9 | MP0006082_CNS_inflammation | 2.53050393 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.41873186 |
| 11 | MP0002102_abnormal_ear_morphology | 2.30811847 |
| 12 | MP0002166_altered_tumor_susceptibility | 2.21290844 |
| 13 | MP0001800_abnormal_humoral_immune | 2.17232559 |
| 14 | MP0003866_abnormal_defecation | 2.14259732 |
| 15 | MP0001790_abnormal_immune_system | 2.12699188 |
| 16 | MP0005387_immune_system_phenotype | 2.12699188 |
| 17 | MP0005025_abnormal_response_to | 2.12220710 |
| 18 | MP0000685_abnormal_immune_system | 2.11167218 |
| 19 | MP0002420_abnormal_adaptive_immunity | 2.09252351 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.04534321 |
| 21 | MP0001819_abnormal_immune_cell | 2.00396955 |
| 22 | MP0002723_abnormal_immune_serum | 1.99553352 |
| 23 | MP0002006_tumorigenesis | 1.86528600 |
| 24 | MP0002405_respiratory_system_inflammati | 1.80077773 |
| 25 | MP0005377_hearing/vestibular/ear_phenot | 1.69798989 |
| 26 | MP0003878_abnormal_ear_physiology | 1.69798989 |
| 27 | MP0003646_muscle_fatigue | 1.66998327 |
| 28 | MP0002398_abnormal_bone_marrow | 1.66653944 |
| 29 | MP0000716_abnormal_immune_system | 1.63496856 |
| 30 | MP0003806_abnormal_nucleotide_metabolis | 1.63488080 |
| 31 | MP0002452_abnormal_antigen_presenting | 1.58645684 |
| 32 | MP0001853_heart_inflammation | 1.57788579 |
| 33 | MP0000703_abnormal_thymus_morphology | 1.56694014 |
| 34 | MP0002722_abnormal_immune_system | 1.50256717 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.48692739 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.46491287 |
| 37 | MP0002933_joint_inflammation | 1.43231063 |
| 38 | MP0002277_abnormal_respiratory_mucosa | 1.41646370 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.40055504 |
| 40 | MP0003448_altered_tumor_morphology | 1.38194524 |
| 41 | MP0001905_abnormal_dopamine_level | 1.38099705 |
| 42 | MP0008875_abnormal_xenobiotic_pharmacok | 1.34133415 |
| 43 | MP0002429_abnormal_blood_cell | 1.32365000 |
| 44 | MP0005645_abnormal_hypothalamus_physiol | 1.30766736 |
| 45 | MP0003693_abnormal_embryo_hatching | 1.30687116 |
| 46 | MP0010155_abnormal_intestine_physiology | 1.30072794 |
| 47 | MP0001919_abnormal_reproductive_system | 1.25003954 |
| 48 | MP0001485_abnormal_pinna_reflex | 1.24894931 |
| 49 | MP0008872_abnormal_physiological_respon | 1.22899876 |
| 50 | MP0004957_abnormal_blastocyst_morpholog | 1.22132969 |
| 51 | MP0006036_abnormal_mitochondrial_physio | 1.19967751 |
| 52 | MP0008007_abnormal_cellular_replicative | 1.17130883 |
| 53 | MP0003137_abnormal_impulse_conducting | 1.15488370 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.14773827 |
| 55 | MP0001661_extended_life_span | 1.14376919 |
| 56 | MP0002736_abnormal_nociception_after | 1.14152877 |
| 57 | MP0008058_abnormal_DNA_repair | 1.05711791 |
| 58 | MP0008995_early_reproductive_senescence | 1.03237874 |
| 59 | MP0009763_increased_sensitivity_to | 1.00367746 |
| 60 | MP0005389_reproductive_system_phenotype | 1.00318530 |
| 61 | MP0003436_decreased_susceptibility_to | 1.00247177 |
| 62 | MP0002419_abnormal_innate_immunity | 0.98569773 |
| 63 | MP0002019_abnormal_tumor_incidence | 0.97793714 |
| 64 | MP0005464_abnormal_platelet_physiology | 0.96229976 |
| 65 | MP0000372_irregular_coat_pigmentation | 0.94806833 |
| 66 | MP0003045_fibrosis | 0.93617850 |
| 67 | MP0002837_dystrophic_cardiac_calcinosis | 0.93533367 |
| 68 | MP0005551_abnormal_eye_electrophysiolog | 0.91630347 |
| 69 | MP0008469_abnormal_protein_level | 0.90110737 |
| 70 | MP0003195_calcinosis | 0.89575207 |
| 71 | MP0002138_abnormal_hepatobiliary_system | 0.89088820 |
| 72 | MP0005636_abnormal_mineral_homeostasis | 0.89035623 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.89033878 |
| 74 | MP0003880_abnormal_central_pattern | 0.88597076 |
| 75 | MP0002876_abnormal_thyroid_physiology | 0.88160906 |
| 76 | MP0002095_abnormal_skin_pigmentation | 0.87652650 |
| 77 | MP0004742_abnormal_vestibular_system | 0.87013706 |
| 78 | MP0002163_abnormal_gland_morphology | 0.85939102 |
| 79 | MP0008789_abnormal_olfactory_epithelium | 0.85421087 |
| 80 | MP0006054_spinal_hemorrhage | 0.82534225 |
| 81 | MP0001968_abnormal_touch/_nociception | 0.81508960 |
| 82 | MP0010386_abnormal_urinary_bladder | 0.79508970 |
| 83 | MP0001188_hyperpigmentation | 0.79260939 |
| 84 | MP0005166_decreased_susceptibility_to | 0.78347266 |
| 85 | MP0009764_decreased_sensitivity_to | 0.78346218 |
| 86 | MP0005083_abnormal_biliary_tract | 0.78272620 |
| 87 | MP0009379_abnormal_foot_pigmentation | 0.78050371 |
| 88 | MP0003011_delayed_dark_adaptation | 0.77105031 |
| 89 | MP0004134_abnormal_chest_morphology | 0.76983585 |
| 90 | MP0005084_abnormal_gallbladder_morpholo | 0.76825402 |
| 91 | MP0003567_abnormal_fetal_cardiomyocyte | 0.76610320 |
| 92 | MP0001119_abnormal_female_reproductive | 0.75711919 |
| 93 | MP0001501_abnormal_sleep_pattern | 0.75055139 |
| 94 | MP0001542_abnormal_bone_strength | 0.72878176 |
| 95 | MP0005075_abnormal_melanosome_morpholog | 0.71624469 |
| 96 | MP0002693_abnormal_pancreas_physiology | 0.71518594 |
| 97 | MP0008877_abnormal_DNA_methylation | 0.69225820 |
| 98 | MP0001727_abnormal_embryo_implantation | 0.67457256 |
| 99 | MP0003111_abnormal_nucleus_morphology | 0.65836094 |
| 100 | MP0005310_abnormal_salivary_gland | 0.65665085 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.39740906 |
| 2 | T lymphocytopenia (HP:0005403) | 4.68242927 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.54869697 |
| 4 | IgG deficiency (HP:0004315) | 4.54441152 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.43744539 |
| 6 | Abnormality of T cell number (HP:0011839) | 4.34887314 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.26144516 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.09588134 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.97848841 |
| 10 | Increased IgM level (HP:0003496) | 3.91397013 |
| 11 | Hypoproteinemia (HP:0003075) | 3.90300612 |
| 12 | Increased CSF lactate (HP:0002490) | 3.86024525 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.84413096 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.78228906 |
| 15 | Acute encephalopathy (HP:0006846) | 3.73002911 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.69274992 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.61355012 |
| 18 | Hepatic necrosis (HP:0002605) | 3.53926259 |
| 19 | Severe combined immunodeficiency (HP:0004430) | 3.50971215 |
| 20 | Autoimmune hemolytic anemia (HP:0001890) | 3.41703648 |
| 21 | Stomatitis (HP:0010280) | 3.40506235 |
| 22 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.38025164 |
| 23 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.38025164 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 3.28706969 |
| 25 | Abnormality of T cells (HP:0002843) | 3.19121521 |
| 26 | Cerebral edema (HP:0002181) | 3.14847330 |
| 27 | B lymphocytopenia (HP:0010976) | 3.05216464 |
| 28 | Increased muscle lipid content (HP:0009058) | 3.04683080 |
| 29 | Pancytopenia (HP:0001876) | 2.99986944 |
| 30 | 3-Methylglutaconic aciduria (HP:0003535) | 2.97742219 |
| 31 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.95765899 |
| 32 | Abnormality of B cell number (HP:0010975) | 2.94209944 |
| 33 | Increased serum lactate (HP:0002151) | 2.87046451 |
| 34 | Combined immunodeficiency (HP:0005387) | 2.85690180 |
| 35 | Generalized aminoaciduria (HP:0002909) | 2.82735596 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.76784691 |
| 37 | Exertional dyspnea (HP:0002875) | 2.75113125 |
| 38 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.72101715 |
| 39 | IgM deficiency (HP:0002850) | 2.71113493 |
| 40 | Lactic acidosis (HP:0003128) | 2.68546110 |
| 41 | Abnormality of the prostate (HP:0008775) | 2.68253330 |
| 42 | Thyroiditis (HP:0100646) | 2.66960367 |
| 43 | Pancreatic cysts (HP:0001737) | 2.53495841 |
| 44 | Exercise intolerance (HP:0003546) | 2.47873296 |
| 45 | Congenital stationary night blindness (HP:0007642) | 2.43748837 |
| 46 | Abnormality of eosinophils (HP:0001879) | 2.42359585 |
| 47 | Encephalitis (HP:0002383) | 2.42317254 |
| 48 | Lymphopenia (HP:0001888) | 2.39840936 |
| 49 | Methylmalonic aciduria (HP:0012120) | 2.37592548 |
| 50 | Chronic diarrhea (HP:0002028) | 2.28389494 |
| 51 | Optic disc pallor (HP:0000543) | 2.28183362 |
| 52 | Hypoalbuminemia (HP:0003073) | 2.27817503 |
| 53 | Abnormal albumin level (HP:0012116) | 2.27817503 |
| 54 | Respiratory failure (HP:0002878) | 2.27063680 |
| 55 | Lethargy (HP:0001254) | 2.22068045 |
| 56 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.18649540 |
| 57 | Hypoplasia of the thymus (HP:0000778) | 2.16696882 |
| 58 | Type I transferrin isoform profile (HP:0003642) | 2.14607782 |
| 59 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.12673509 |
| 60 | Gastrointestinal infarctions (HP:0005244) | 2.10730125 |
| 61 | Recurrent bronchitis (HP:0002837) | 2.10246419 |
| 62 | Methylmalonic acidemia (HP:0002912) | 2.07179611 |
| 63 | Acute hepatic failure (HP:0006554) | 2.06991440 |
| 64 | Eosinophilia (HP:0001880) | 2.06514416 |
| 65 | True hermaphroditism (HP:0010459) | 2.04604331 |
| 66 | Hyperglycinemia (HP:0002154) | 2.01532772 |
| 67 | Dicarboxylic aciduria (HP:0003215) | 2.00844657 |
| 68 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.00844657 |
| 69 | Severe visual impairment (HP:0001141) | 2.00826816 |
| 70 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.00371042 |
| 71 | Meningitis (HP:0001287) | 1.98734645 |
| 72 | Abnormality of midbrain morphology (HP:0002418) | 1.95575173 |
| 73 | Molar tooth sign on MRI (HP:0002419) | 1.95575173 |
| 74 | Amyotrophic lateral sclerosis (HP:0007354) | 1.95481147 |
| 75 | Pendular nystagmus (HP:0012043) | 1.93829465 |
| 76 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.92318042 |
| 77 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.91062689 |
| 78 | Abnormality of renal resorption (HP:0011038) | 1.88752127 |
| 79 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.87178418 |
| 80 | Abnormality of alanine metabolism (HP:0010916) | 1.87178418 |
| 81 | Hyperalaninemia (HP:0003348) | 1.87178418 |
| 82 | Abolished electroretinogram (ERG) (HP:0000550) | 1.85890570 |
| 83 | Abnormality of T cell physiology (HP:0011840) | 1.85480139 |
| 84 | Glycosuria (HP:0003076) | 1.84550070 |
| 85 | Abnormality of urine glucose concentration (HP:0011016) | 1.84550070 |
| 86 | Pancreatic fibrosis (HP:0100732) | 1.83360405 |
| 87 | Respiratory difficulties (HP:0002880) | 1.83166233 |
| 88 | Oral leukoplakia (HP:0002745) | 1.82885708 |
| 89 | Gangrene (HP:0100758) | 1.82633821 |
| 90 | Decreased central vision (HP:0007663) | 1.82436985 |
| 91 | Leukodystrophy (HP:0002415) | 1.81553423 |
| 92 | Attenuation of retinal blood vessels (HP:0007843) | 1.80116656 |
| 93 | Cerebral palsy (HP:0100021) | 1.79303102 |
| 94 | Agammaglobulinemia (HP:0004432) | 1.78501581 |
| 95 | Bronchitis (HP:0012387) | 1.78381045 |
| 96 | Renal cortical cysts (HP:0000803) | 1.78145800 |
| 97 | Joint swelling (HP:0001386) | 1.77457193 |
| 98 | Lymphoma (HP:0002665) | 1.76850699 |
| 99 | Congenital, generalized hypertrichosis (HP:0004540) | 1.76489149 |
| 100 | Emotional lability (HP:0000712) | 1.73912209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 6.14412440 |
| 2 | KDR | 5.78583189 |
| 3 | TXK | 5.19724140 |
| 4 | BUB1 | 3.62272743 |
| 5 | BCKDK | 3.54163682 |
| 6 | VRK2 | 3.45659764 |
| 7 | TESK1 | 2.57605539 |
| 8 | MAP4K1 | 2.44110754 |
| 9 | MST4 | 2.12171508 |
| 10 | LIMK1 | 2.04266417 |
| 11 | ITK | 1.86905481 |
| 12 | ZAK | 1.66698174 |
| 13 | VRK1 | 1.55174244 |
| 14 | ADRBK2 | 1.52769315 |
| 15 | GRK1 | 1.50200905 |
| 16 | EIF2AK3 | 1.37775393 |
| 17 | MAP3K12 | 1.36234920 |
| 18 | TAOK3 | 1.34821808 |
| 19 | NUAK1 | 1.33709469 |
| 20 | TEC | 1.32946969 |
| 21 | MAPKAPK3 | 1.30583293 |
| 22 | SRPK1 | 1.30040804 |
| 23 | SCYL2 | 1.27880515 |
| 24 | MUSK | 1.24768316 |
| 25 | NME1 | 1.21725162 |
| 26 | EIF2AK1 | 1.10529512 |
| 27 | DAPK1 | 1.10089005 |
| 28 | MAP4K2 | 1.06823474 |
| 29 | TLK1 | 1.03461029 |
| 30 | PRKCQ | 1.03004272 |
| 31 | SYK | 1.01597278 |
| 32 | TRIM28 | 0.96081671 |
| 33 | CSK | 0.94958044 |
| 34 | WNK4 | 0.91778418 |
| 35 | MAP3K11 | 0.90968283 |
| 36 | RPS6KA4 | 0.88786785 |
| 37 | LCK | 0.88446876 |
| 38 | CSNK1G3 | 0.87713787 |
| 39 | GRK7 | 0.86754154 |
| 40 | BTK | 0.85339237 |
| 41 | GRK6 | 0.84060098 |
| 42 | CDC7 | 0.82301406 |
| 43 | FES | 0.77087280 |
| 44 | STK16 | 0.76373783 |
| 45 | RPS6KA5 | 0.74213345 |
| 46 | ZAP70 | 0.73100774 |
| 47 | MAP2K7 | 0.71862796 |
| 48 | OXSR1 | 0.70207876 |
| 49 | PAK4 | 0.69974567 |
| 50 | CSNK1A1L | 0.68152312 |
| 51 | STK39 | 0.67190330 |
| 52 | MYLK | 0.65985363 |
| 53 | PLK4 | 0.65140862 |
| 54 | CSNK1G1 | 0.63201277 |
| 55 | TNK2 | 0.63155570 |
| 56 | NME2 | 0.62468604 |
| 57 | BCR | 0.62411154 |
| 58 | LYN | 0.58710889 |
| 59 | AURKA | 0.56704165 |
| 60 | CSNK1G2 | 0.55467683 |
| 61 | INSRR | 0.55406242 |
| 62 | WNK3 | 0.52224692 |
| 63 | PIM2 | 0.50763122 |
| 64 | TIE1 | 0.50095261 |
| 65 | ATR | 0.49745622 |
| 66 | NEK1 | 0.48051172 |
| 67 | PLK1 | 0.47462358 |
| 68 | IKBKB | 0.46509697 |
| 69 | IKBKE | 0.43852406 |
| 70 | ERBB3 | 0.42772328 |
| 71 | MAP2K6 | 0.42556863 |
| 72 | PLK3 | 0.41356368 |
| 73 | CDK19 | 0.41329673 |
| 74 | TBK1 | 0.40568939 |
| 75 | CSF1R | 0.39818270 |
| 76 | OBSCN | 0.39491844 |
| 77 | TSSK6 | 0.38706163 |
| 78 | PIK3CG | 0.38570466 |
| 79 | GRK5 | 0.38494374 |
| 80 | PAK1 | 0.37949241 |
| 81 | CSNK2A1 | 0.37941059 |
| 82 | IGF1R | 0.36965348 |
| 83 | JAK3 | 0.35922888 |
| 84 | AURKB | 0.34462781 |
| 85 | ROCK1 | 0.33767882 |
| 86 | PINK1 | 0.33725038 |
| 87 | FYN | 0.32776361 |
| 88 | CSNK1A1 | 0.32137627 |
| 89 | INSR | 0.30317530 |
| 90 | CSNK2A2 | 0.29943151 |
| 91 | STK10 | 0.29105838 |
| 92 | PIK3CA | 0.28826912 |
| 93 | FRK | 0.28602212 |
| 94 | PRKCA | 0.27718831 |
| 95 | EIF2AK2 | 0.25297152 |
| 96 | CAMK2A | 0.23110701 |
| 97 | PIM1 | 0.22829942 |
| 98 | TAF1 | 0.22622450 |
| 99 | PRKACA | 0.22343640 |
| 100 | ADRBK1 | 0.22237780 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.93328016 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.86141635 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.64466433 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.18568935 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.53493332 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.43974890 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.42213514 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.28706690 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.27909720 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.26760667 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.21014725 |
| 12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.16083328 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.11146699 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 2.00531953 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 1.94872044 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.89434026 |
| 17 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.86956629 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.82884983 |
| 19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.68735937 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.66134567 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.65874253 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.40500480 |
| 23 | Homologous recombination_Homo sapiens_hsa03440 | 1.38524555 |
| 24 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.35938035 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.35809288 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33735622 |
| 27 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.33237076 |
| 28 | Mismatch repair_Homo sapiens_hsa03430 | 1.18965464 |
| 29 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.16994122 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.15607828 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.11296304 |
| 32 | Measles_Homo sapiens_hsa05162 | 1.10933830 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.09560854 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 1.07481703 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.05115197 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.03000481 |
| 37 | Spliceosome_Homo sapiens_hsa03040 | 1.02934371 |
| 38 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.01617050 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 0.98045757 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.98015457 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.94782814 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.94535149 |
| 43 | Salmonella infection_Homo sapiens_hsa05132 | 0.93238983 |
| 44 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.85066938 |
| 45 | Shigellosis_Homo sapiens_hsa05131 | 0.84851605 |
| 46 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.84573754 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.82471836 |
| 48 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.82462098 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.79107377 |
| 50 | Basal transcription factors_Homo sapiens_hsa03022 | 0.78087723 |
| 51 | Viral myocarditis_Homo sapiens_hsa05416 | 0.75864742 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74655288 |
| 53 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.69727665 |
| 54 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68034542 |
| 55 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.68016734 |
| 56 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.67440698 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.65175319 |
| 58 | RNA transport_Homo sapiens_hsa03013 | 0.64775901 |
| 59 | Malaria_Homo sapiens_hsa05144 | 0.64184083 |
| 60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63430480 |
| 61 | Base excision repair_Homo sapiens_hsa03410 | 0.63408645 |
| 62 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.62842341 |
| 63 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.61964900 |
| 64 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.53305084 |
| 65 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.51172128 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49400284 |
| 67 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48633300 |
| 68 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.47437879 |
| 69 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.46359807 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.46291673 |
| 71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46185351 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45864152 |
| 73 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.45639783 |
| 74 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45279020 |
| 75 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.40989678 |
| 76 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.39688613 |
| 77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.39624948 |
| 78 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.37057319 |
| 79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36927104 |
| 80 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.35255778 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.34536601 |
| 82 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.33834992 |
| 83 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33497215 |
| 84 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.32014479 |
| 85 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.31686072 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.31320838 |
| 87 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.30037090 |
| 88 | HTLV-I infection_Homo sapiens_hsa05166 | 0.29712817 |
| 89 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.29346530 |
| 90 | Olfactory transduction_Homo sapiens_hsa04740 | 0.28445354 |
| 91 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.26932766 |
| 92 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.22458812 |
| 93 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21585391 |
| 94 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.20868708 |
| 95 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.20608164 |
| 96 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.18983855 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.18696175 |
| 98 | Legionellosis_Homo sapiens_hsa05134 | 0.17026406 |
| 99 | Carbon metabolism_Homo sapiens_hsa01200 | 0.15735592 |
| 100 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.15334904 |

