Rank | Gene Set | Z-score |
---|---|---|
1 | rRNA methylation (GO:0031167) | 8.05542894 |
2 | rRNA modification (GO:0000154) | 6.98167895 |
3 | positive regulation of granulocyte differentiation (GO:0030854) | 6.14750091 |
4 | thrombin receptor signaling pathway (GO:0070493) | 5.42557002 |
5 | negative regulation of granulocyte differentiation (GO:0030853) | 5.26830975 |
6 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.24512123 |
7 | definitive hemopoiesis (GO:0060216) | 4.93342627 |
8 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.86232072 |
9 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.86232072 |
10 | regulation of platelet aggregation (GO:0090330) | 4.79833695 |
11 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 4.70488381 |
12 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 4.60984762 |
13 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.54900096 |
14 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.37498633 |
15 | negative regulation of norepinephrine secretion (GO:0010700) | 4.28185380 |
16 | embryonic process involved in female pregnancy (GO:0060136) | 4.16375577 |
17 | positive regulation by symbiont of host defense response (GO:0052509) | 4.07225561 |
18 | modulation by symbiont of host defense response (GO:0052031) | 4.07225561 |
19 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.07225561 |
20 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.07225561 |
21 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.07225561 |
22 | modulation by symbiont of host immune response (GO:0052553) | 4.07225561 |
23 | neutrophil activation involved in immune response (GO:0002283) | 4.05331981 |
24 | megakaryocyte development (GO:0035855) | 3.98627852 |
25 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.95459088 |
26 | regulation of granulocyte differentiation (GO:0030852) | 3.94446537 |
27 | regulation of platelet activation (GO:0010543) | 3.92184306 |
28 | regulation of female gonad development (GO:2000194) | 3.74619148 |
29 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.71286493 |
30 | granulocyte differentiation (GO:0030851) | 3.66847228 |
31 | positive regulation of steroid hormone secretion (GO:2000833) | 3.65406348 |
32 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.59899632 |
33 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.59183422 |
34 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.57470789 |
35 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.52567264 |
36 | regulation of interferon-alpha production (GO:0032647) | 3.39514102 |
37 | positive regulation of interferon-alpha production (GO:0032727) | 3.38602898 |
38 | immunoglobulin mediated immune response (GO:0016064) | 3.37177772 |
39 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.34278944 |
40 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.31862814 |
41 | adenosine receptor signaling pathway (GO:0001973) | 3.30232656 |
42 | response to peptidoglycan (GO:0032494) | 3.30008697 |
43 | negative regulation of stress fiber assembly (GO:0051497) | 3.29907258 |
44 | regulation of penile erection (GO:0060405) | 3.28241807 |
45 | positive regulation of mast cell activation (GO:0033005) | 3.27162390 |
46 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.26502807 |
47 | leukocyte aggregation (GO:0070486) | 3.26200202 |
48 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.25227387 |
49 | regulation of gamma-delta T cell activation (GO:0046643) | 3.21951114 |
50 | response to pheromone (GO:0019236) | 3.19576850 |
51 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.17281210 |
52 | regulation of integrin activation (GO:0033623) | 3.15183823 |
53 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.14499080 |
54 | T cell migration (GO:0072678) | 3.13449462 |
55 | myeloid cell development (GO:0061515) | 3.08589412 |
56 | respiratory burst (GO:0045730) | 3.06611584 |
57 | macrophage activation involved in immune response (GO:0002281) | 3.05821263 |
58 | response to muramyl dipeptide (GO:0032495) | 3.05219542 |
59 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.04625506 |
60 | regulation of regulatory T cell differentiation (GO:0045589) | 3.04010171 |
61 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.03994381 |
62 | response to type I interferon (GO:0034340) | 3.02509213 |
63 | positive regulation of macrophage differentiation (GO:0045651) | 3.02181280 |
64 | granulocyte activation (GO:0036230) | 3.01724763 |
65 | myeloid dendritic cell activation (GO:0001773) | 2.99866304 |
66 | neutrophil activation (GO:0042119) | 2.99795737 |
67 | type I interferon signaling pathway (GO:0060337) | 2.98995490 |
68 | cellular response to type I interferon (GO:0071357) | 2.98995490 |
69 | positive regulation of male gonad development (GO:2000020) | 2.98202947 |
70 | interferon-gamma production (GO:0032609) | 2.97622213 |
71 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.94327658 |
72 | negative regulation of cell killing (GO:0031342) | 2.94327658 |
73 | hepatocyte apoptotic process (GO:0097284) | 2.93495177 |
74 | negative regulation of interleukin-12 production (GO:0032695) | 2.93263536 |
75 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.90403545 |
76 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.88752609 |
77 | peripheral nervous system neuron development (GO:0048935) | 2.87954565 |
78 | response to protozoan (GO:0001562) | 2.87551787 |
79 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.87457729 |
80 | cellular extravasation (GO:0045123) | 2.87051392 |
81 | positive regulation of B cell differentiation (GO:0045579) | 2.86987256 |
82 | positive regulation of isotype switching (GO:0045830) | 2.85997884 |
83 | relaxation of smooth muscle (GO:0044557) | 2.85698945 |
84 | leukocyte cell-cell adhesion (GO:0007159) | 2.85084640 |
85 | protein neddylation (GO:0045116) | 2.85057806 |
86 | defense response to protozoan (GO:0042832) | 2.83466925 |
87 | negative regulation of T cell mediated immunity (GO:0002710) | 2.83359740 |
88 | positive regulation of antigen processing and presentation (GO:0002579) | 2.81887689 |
89 | myeloid dendritic cell differentiation (GO:0043011) | 2.80085046 |
90 | regulation of mast cell activation (GO:0033003) | 2.76620095 |
91 | positive regulation of interleukin-17 production (GO:0032740) | 2.75737127 |
92 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.75682770 |
93 | regulation of pigment cell differentiation (GO:0050932) | 2.74682118 |
94 | negative thymic T cell selection (GO:0045060) | 2.73743616 |
95 | NIK/NF-kappaB signaling (GO:0038061) | 2.73431541 |
96 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.73367792 |
97 | myeloid cell activation involved in immune response (GO:0002275) | 2.73308367 |
98 | positive thymic T cell selection (GO:0045059) | 2.72489704 |
99 | embryonic hemopoiesis (GO:0035162) | 2.72247079 |
100 | B cell mediated immunity (GO:0019724) | 2.72100816 |
101 | positive regulation of interferon-beta production (GO:0032728) | 2.71303826 |
102 | regulation of B cell differentiation (GO:0045577) | 2.71295608 |
103 | negative regulation of platelet activation (GO:0010544) | 2.70637052 |
104 | tolerance induction (GO:0002507) | 2.70635181 |
105 | negative regulation of T cell apoptotic process (GO:0070233) | 2.70047809 |
106 | negative T cell selection (GO:0043383) | 2.69587703 |
107 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.68229832 |
108 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 2.67785851 |
109 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.67678136 |
110 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.67678136 |
111 | positive regulation of interleukin-2 production (GO:0032743) | 2.67436085 |
112 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.67380523 |
113 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.67380523 |
114 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 2.66534169 |
115 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.65963409 |
116 | actin nucleation (GO:0045010) | 2.63325838 |
117 | response to host immune response (GO:0052572) | 2.63275296 |
118 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.63275296 |
119 | negative regulation of B cell proliferation (GO:0030889) | 2.62403759 |
120 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.61568897 |
121 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.61439650 |
122 | negative regulation of phagocytosis (GO:0050765) | 2.60054984 |
123 | pinocytosis (GO:0006907) | 2.59663402 |
124 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.58311657 |
125 | endothelium development (GO:0003158) | 2.57160866 |
126 | response to host (GO:0075136) | 2.56991097 |
127 | response to host defenses (GO:0052200) | 2.56991097 |
128 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.56991097 |
129 | hematopoietic stem cell proliferation (GO:0071425) | 2.56829172 |
130 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.56628856 |
131 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.56453122 |
132 | COPI coating of Golgi vesicle (GO:0048205) | 2.55981747 |
133 | Golgi transport vesicle coating (GO:0048200) | 2.55981747 |
134 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.54599058 |
135 | B cell receptor signaling pathway (GO:0050853) | 2.54460704 |
136 | leukocyte degranulation (GO:0043299) | 2.53973124 |
137 | positive regulation of T-helper cell differentiation (GO:0045624) | 2.53777954 |
138 | programmed necrotic cell death (GO:0097300) | 2.53595764 |
139 | response to interferon-beta (GO:0035456) | 2.53060016 |
140 | regulation of response to interferon-gamma (GO:0060330) | 2.52423431 |
141 | response to interleukin-15 (GO:0070672) | 2.52325836 |
142 | cellular response to arsenic-containing substance (GO:0071243) | 2.52240309 |
143 | regulation of memory T cell differentiation (GO:0043380) | 2.52047414 |
144 | erythrocyte development (GO:0048821) | 2.51812774 |
145 | positive regulation of B cell mediated immunity (GO:0002714) | 2.51694327 |
146 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.51694327 |
147 | regulation of antigen processing and presentation (GO:0002577) | 2.51289148 |
148 | regulation of interleukin-17 production (GO:0032660) | 2.48855774 |
149 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.48114289 |
150 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.47859549 |
151 | endocardial cushion development (GO:0003197) | 2.47654085 |
152 | germinal center formation (GO:0002467) | 2.47325508 |
153 | growth hormone receptor signaling pathway (GO:0060396) | 2.47104689 |
154 | myeloid leukocyte activation (GO:0002274) | 2.46802326 |
155 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.45593108 |
156 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.45223141 |
157 | signal peptide processing (GO:0006465) | 2.45092550 |
158 | cellular response to interferon-beta (GO:0035458) | 2.44206705 |
159 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.43755744 |
160 | regulation of T-helper 1 type immune response (GO:0002825) | 2.43612236 |
161 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.43487969 |
162 | autophagic vacuole fusion (GO:0000046) | 2.43198748 |
163 | positive regulation of DNA recombination (GO:0045911) | 2.41356835 |
164 | cellular defense response (GO:0006968) | 2.41029827 |
165 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.41005195 |
166 | regulation of T cell chemotaxis (GO:0010819) | 2.40574363 |
167 | positive regulation of T cell chemotaxis (GO:0010820) | 2.40574363 |
168 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.40374760 |
169 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.39780172 |
170 | negative regulation of actin filament bundle assembly (GO:0032232) | 2.38253329 |
171 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.37950831 |
172 | necrotic cell death (GO:0070265) | 2.37732097 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.83320554 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.57113994 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.96631351 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.84075694 |
5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.75004324 |
6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.39569784 |
7 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.24957382 |
8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.16588058 |
9 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.09901152 |
10 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.01816584 |
11 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.98951645 |
12 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.96018251 |
13 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.95447610 |
14 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.95276515 |
15 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.82410401 |
16 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.82135234 |
17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.74247611 |
18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.54178962 |
19 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.48460498 |
20 | MYB_26560356_Chip-Seq_TH2_Human | 2.36031329 |
21 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.32863542 |
22 | MYC_22102868_ChIP-Seq_BL_Human | 2.26266484 |
23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.24647859 |
24 | * SCL_19346495_ChIP-Seq_HPC-7_Human | 2.24543936 |
25 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.24502330 |
26 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.23212659 |
27 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 2.19846264 |
28 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.18938993 |
29 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.15206566 |
30 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.14516359 |
31 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 2.04960392 |
32 | MAF_26560356_Chip-Seq_TH1_Human | 2.04013152 |
33 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.03805224 |
34 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.03596105 |
35 | * MYB_26560356_Chip-Seq_TH1_Human | 1.96749388 |
36 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.95575058 |
37 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.94672963 |
38 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.93360889 |
39 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.85660530 |
40 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.79602063 |
41 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.79266247 |
42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.74177157 |
43 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.67247626 |
44 | GATA1_22025678_ChIP-Seq_K562_Human | 1.64694522 |
45 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.63494432 |
46 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.63396044 |
47 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.58246896 |
48 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57103653 |
49 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56379385 |
50 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.55815621 |
51 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.54565575 |
52 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52752187 |
53 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.49085807 |
54 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.46864990 |
55 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46836351 |
56 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.46784421 |
57 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.46210996 |
58 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.45745553 |
59 | SPI1_23127762_ChIP-Seq_K562_Human | 1.42585337 |
60 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.42278601 |
61 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.39783686 |
62 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.36264888 |
63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.32913852 |
64 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.32388833 |
65 | * GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.28385940 |
66 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.27615315 |
67 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.27434175 |
68 | * CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.25400981 |
69 | GATA1_19941826_ChIP-Seq_K562_Human | 1.25170505 |
70 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.25015468 |
71 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.23741482 |
72 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.23741482 |
73 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23679627 |
74 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.22524876 |
75 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22158698 |
76 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.20272465 |
77 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.19924243 |
78 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.18723736 |
79 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.18569264 |
80 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17797795 |
81 | VDR_22108803_ChIP-Seq_LS180_Human | 1.17335636 |
82 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.17300285 |
83 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.14321385 |
84 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.13777967 |
85 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.13241523 |
86 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.12657666 |
87 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.12323793 |
88 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.12070505 |
89 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.12018252 |
90 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.11778431 |
91 | MAF_26560356_Chip-Seq_TH2_Human | 1.10926216 |
92 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.10778064 |
93 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10042183 |
94 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.05949866 |
95 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.04307025 |
96 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.04173071 |
97 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02943782 |
98 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.02816545 |
99 | * CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.01699975 |
100 | GATA2_19941826_ChIP-Seq_K562_Human | 1.01380697 |
101 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.01093949 |
102 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.00638167 |
103 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.00598755 |
104 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00369300 |
105 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.00086653 |
106 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.99735095 |
107 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.99717480 |
108 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.99667643 |
109 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98505275 |
110 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.96901544 |
111 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.96901544 |
112 | GATA3_26560356_Chip-Seq_TH1_Human | 0.96072119 |
113 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.95357582 |
114 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.94217723 |
115 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.94013765 |
116 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.92212393 |
117 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.92095203 |
118 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.91501870 |
119 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.91328316 |
120 | FUS_26573619_Chip-Seq_HEK293_Human | 0.91283211 |
121 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.90639631 |
122 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.89828961 |
123 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89564860 |
124 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.88897668 |
125 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88475970 |
126 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.87090574 |
127 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.86987000 |
128 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.86873485 |
129 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.85946967 |
130 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.85753632 |
131 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.85737295 |
132 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.85233483 |
133 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.85064670 |
134 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.84691429 |
135 | * ER_23166858_ChIP-Seq_MCF-7_Human | 0.84104846 |
136 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.83626451 |
137 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.82015111 |
138 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.80987409 |
139 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.80825172 |
140 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.78972481 |
141 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.78166520 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.55369438 |
2 | MP0003436_decreased_susceptibility_to | 3.04491110 |
3 | MP0005671_abnormal_response_to | 2.84322742 |
4 | MP0003303_peritoneal_inflammation | 2.78278233 |
5 | MP0009785_altered_susceptibility_to | 2.74627702 |
6 | MP0005000_abnormal_immune_tolerance | 2.68342428 |
7 | MP0000685_abnormal_immune_system | 2.68240176 |
8 | MP0009697_abnormal_copulation | 2.57200457 |
9 | MP0003300_gastrointestinal_ulcer | 2.56334699 |
10 | MP0002148_abnormal_hypersensitivity_rea | 2.54433026 |
11 | MP0003724_increased_susceptibility_to | 2.50829432 |
12 | MP0005387_immune_system_phenotype | 2.49198506 |
13 | MP0001790_abnormal_immune_system | 2.49198506 |
14 | MP0001800_abnormal_humoral_immune | 2.41549929 |
15 | MP0005025_abnormal_response_to | 2.37295994 |
16 | MP0002419_abnormal_innate_immunity | 2.37251250 |
17 | MP0002452_abnormal_antigen_presenting | 2.36282033 |
18 | MP0006082_CNS_inflammation | 2.24769269 |
19 | MP0002723_abnormal_immune_serum | 2.24613916 |
20 | MP0002420_abnormal_adaptive_immunity | 2.18123565 |
21 | MP0001819_abnormal_immune_cell | 2.17427446 |
22 | MP0003763_abnormal_thymus_physiology | 2.15957508 |
23 | MP0002166_altered_tumor_susceptibility | 2.06564478 |
24 | MP0004510_myositis | 1.99454340 |
25 | MP0002405_respiratory_system_inflammati | 1.97988220 |
26 | * MP0005464_abnormal_platelet_physiology | 1.97024708 |
27 | MP0002877_abnormal_melanocyte_morpholog | 1.95875804 |
28 | MP0002398_abnormal_bone_marrow | 1.88245550 |
29 | MP0002006_tumorigenesis | 1.86539899 |
30 | MP0005058_abnormal_lysosome_morphology | 1.85087361 |
31 | MP0009333_abnormal_splenocyte_physiolog | 1.83427863 |
32 | MP0010155_abnormal_intestine_physiology | 1.81809955 |
33 | MP0005084_abnormal_gallbladder_morpholo | 1.81132562 |
34 | MP0004947_skin_inflammation | 1.80842545 |
35 | MP0003806_abnormal_nucleotide_metabolis | 1.79405761 |
36 | MP0001533_abnormal_skeleton_physiology | 1.78285041 |
37 | MP0008004_abnormal_stomach_pH | 1.76326038 |
38 | MP0000716_abnormal_immune_system | 1.74266112 |
39 | MP0001845_abnormal_inflammatory_respons | 1.72964535 |
40 | MP0001853_heart_inflammation | 1.69872877 |
41 | MP0006054_spinal_hemorrhage | 1.68023739 |
42 | MP0003448_altered_tumor_morphology | 1.66223750 |
43 | MP0010352_gastrointestinal_tract_polyps | 1.65871819 |
44 | MP0004808_abnormal_hematopoietic_stem | 1.63855369 |
45 | MP0000858_altered_metastatic_potential | 1.56073458 |
46 | MP0005397_hematopoietic_system_phenotyp | 1.56011537 |
47 | MP0001545_abnormal_hematopoietic_system | 1.56011537 |
48 | MP0000465_gastrointestinal_hemorrhage | 1.55999874 |
49 | MP0000689_abnormal_spleen_morphology | 1.55275569 |
50 | MP0000015_abnormal_ear_pigmentation | 1.54606440 |
51 | MP0002396_abnormal_hematopoietic_system | 1.52982409 |
52 | MP0003172_abnormal_lysosome_physiology | 1.52895953 |
53 | MP0002722_abnormal_immune_system | 1.49421577 |
54 | MP0009384_cardiac_valve_regurgitation | 1.49035313 |
55 | MP0002429_abnormal_blood_cell | 1.48385628 |
56 | MP0002933_joint_inflammation | 1.46780694 |
57 | MP0001873_stomach_inflammation | 1.43048881 |
58 | MP0002138_abnormal_hepatobiliary_system | 1.40731168 |
59 | MP0004084_abnormal_cardiac_muscle | 1.33875672 |
60 | MP0003566_abnormal_cell_adhesion | 1.32226277 |
61 | MP0005076_abnormal_cell_differentiation | 1.32218804 |
62 | MP0009278_abnormal_bone_marrow | 1.30066982 |
63 | MP0008469_abnormal_protein_level | 1.29623495 |
64 | MP0000013_abnormal_adipose_tissue | 1.28121412 |
65 | MP0005310_abnormal_salivary_gland | 1.27383668 |
66 | MP0000490_abnormal_crypts_of | 1.26692499 |
67 | MP0003183_abnormal_peptide_metabolism | 1.26335482 |
68 | MP0000343_altered_response_to | 1.26063293 |
69 | MP0002998_abnormal_bone_remodeling | 1.25785170 |
70 | MP0000703_abnormal_thymus_morphology | 1.21535653 |
71 | MP0003866_abnormal_defecation | 1.20484153 |
72 | MP0003656_abnormal_erythrocyte_physiolo | 1.17224128 |
73 | MP0010307_abnormal_tumor_latency | 1.14151633 |
74 | MP0003828_pulmonary_edema | 1.10426206 |
75 | MP0005075_abnormal_melanosome_morpholog | 1.00912020 |
76 | MP0005167_abnormal_blood-brain_barrier | 1.00567226 |
77 | MP0003279_aneurysm | 1.00002140 |
78 | MP0005023_abnormal_wound_healing | 0.99922750 |
79 | MP0005390_skeleton_phenotype | 0.97599363 |
80 | MP0009764_decreased_sensitivity_to | 0.96583213 |
81 | MP0003191_abnormal_cellular_cholesterol | 0.95882276 |
82 | MP0004484_altered_response_of | 0.94561042 |
83 | MP0001851_eye_inflammation | 0.93749653 |
84 | MP0003795_abnormal_bone_structure | 0.92999752 |
85 | MP0002132_abnormal_respiratory_system | 0.92307981 |
86 | MP0002693_abnormal_pancreas_physiology | 0.89610376 |
87 | MP0005174_abnormal_tail_pigmentation | 0.88066378 |
88 | MP0004782_abnormal_surfactant_physiolog | 0.87334062 |
89 | MP0008438_abnormal_cutaneous_collagen | 0.87207589 |
90 | MP0003453_abnormal_keratinocyte_physiol | 0.86491734 |
91 | MP0000230_abnormal_systemic_arterial | 0.86377830 |
92 | MP0005595_abnormal_vascular_smooth | 0.83127258 |
93 | MP0000249_abnormal_blood_vessel | 0.82444335 |
94 | MP0002019_abnormal_tumor_incidence | 0.81358154 |
95 | MP0003075_altered_response_to | 0.81329439 |
96 | MP0001879_abnormal_lymphatic_vessel | 0.80794150 |
97 | MP0000767_abnormal_smooth_muscle | 0.80215544 |
98 | MP0004883_abnormal_blood_vessel | 0.79330783 |
99 | MP0008007_abnormal_cellular_replicative | 0.78507394 |
100 | MP0005164_abnormal_response_to | 0.78489153 |
101 | MP0005165_increased_susceptibility_to | 0.77666301 |
102 | MP0003091_abnormal_cell_migration | 0.77085197 |
103 | MP0003705_abnormal_hypodermis_morpholog | 0.75783472 |
104 | MP0005166_decreased_susceptibility_to | 0.75331207 |
105 | MP0001663_abnormal_digestive_system | 0.73736566 |
106 | MP0009763_increased_sensitivity_to | 0.72252283 |
107 | MP0002136_abnormal_kidney_physiology | 0.70792841 |
108 | MP0001958_emphysema | 0.70513927 |
109 | MP0005379_endocrine/exocrine_gland_phen | 0.70485937 |
110 | MP0001727_abnormal_embryo_implantation | 0.68982985 |
111 | MP0001915_intracranial_hemorrhage | 0.68337749 |
112 | MP0003943_abnormal_hepatobiliary_system | 0.68183092 |
113 | MP0004036_abnormal_muscle_relaxation | 0.68057134 |
114 | MP0002928_abnormal_bile_duct | 0.66754423 |
115 | MP0002009_preneoplasia | 0.64562697 |
116 | MP0000569_abnormal_digit_pigmentation | 0.63073073 |
117 | MP0001881_abnormal_mammary_gland | 0.62417550 |
118 | MP0001188_hyperpigmentation | 0.61376150 |
119 | MP0001191_abnormal_skin_condition | 0.61284027 |
120 | MP0010234_abnormal_vibrissa_follicle | 0.59335963 |
121 | MP0010386_abnormal_urinary_bladder | 0.58779567 |
122 | MP0002095_abnormal_skin_pigmentation | 0.58201404 |
123 | MP0003045_fibrosis | 0.58063839 |
124 | MP0005535_abnormal_body_temperature | 0.57920636 |
125 | MP0000371_diluted_coat_color | 0.57747796 |
126 | MP0003195_calcinosis | 0.56396855 |
127 | MP0003252_abnormal_bile_duct | 0.54802462 |
128 | MP0009765_abnormal_xenobiotic_induced | 0.54649742 |
129 | MP0001348_abnormal_lacrimal_gland | 0.53745238 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Eczematoid dermatitis (HP:0000976) | 5.09056405 |
2 | Recurrent abscess formation (HP:0002722) | 5.04983782 |
3 | Recurrent bacterial skin infections (HP:0005406) | 4.47969058 |
4 | Myositis (HP:0100614) | 4.39365113 |
5 | Orchitis (HP:0100796) | 3.89623183 |
6 | Autoimmune hemolytic anemia (HP:0001890) | 3.84206619 |
7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.75560432 |
8 | Retrobulbar optic neuritis (HP:0100654) | 3.64456855 |
9 | Optic neuritis (HP:0100653) | 3.64456855 |
10 | Recurrent fungal infections (HP:0002841) | 3.41707508 |
11 | Acanthocytosis (HP:0001927) | 3.38726353 |
12 | Aortic aneurysm (HP:0004942) | 3.36882616 |
13 | Abnormality of macrophages (HP:0004311) | 3.33253564 |
14 | Hematochezia (HP:0002573) | 3.32798924 |
15 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.31948982 |
16 | Recurrent viral infections (HP:0004429) | 3.23291525 |
17 | Vacuolated lymphocytes (HP:0001922) | 3.19465932 |
18 | Interstitial pulmonary disease (HP:0006530) | 3.13356562 |
19 | Chronic otitis media (HP:0000389) | 3.10186243 |
20 | Mediastinal lymphadenopathy (HP:0100721) | 3.09481643 |
21 | Acute myeloid leukemia (HP:0004808) | 3.01248419 |
22 | Arterial thrombosis (HP:0004420) | 2.99219461 |
23 | IgM deficiency (HP:0002850) | 2.95948747 |
24 | Recurrent skin infections (HP:0001581) | 2.94899123 |
25 | Systemic lupus erythematosus (HP:0002725) | 2.93999803 |
26 | Abnormality of B cell number (HP:0010975) | 2.89011451 |
27 | Increased cerebral lipofuscin (HP:0011813) | 2.88666571 |
28 | Vasculitis (HP:0002633) | 2.86968193 |
29 | Spontaneous hematomas (HP:0007420) | 2.86634498 |
30 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.85490255 |
31 | Autoimmune thrombocytopenia (HP:0001973) | 2.85170672 |
32 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.84338950 |
33 | Petechiae (HP:0000967) | 2.82827676 |
34 | Conjunctival telangiectasia (HP:0000524) | 2.82320108 |
35 | Pulmonary infiltrates (HP:0002113) | 2.79792665 |
36 | Obstructive lung disease (HP:0006536) | 2.78634223 |
37 | Chronic obstructive pulmonary disease (HP:0006510) | 2.78634223 |
38 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.77647075 |
39 | Abnormality of T cell number (HP:0011839) | 2.77141049 |
40 | Pustule (HP:0200039) | 2.75645138 |
41 | Prolonged bleeding time (HP:0003010) | 2.75240755 |
42 | Dysostosis multiplex (HP:0000943) | 2.73999420 |
43 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.73209786 |
44 | Abnormality of T cell physiology (HP:0011840) | 2.72945101 |
45 | T lymphocytopenia (HP:0005403) | 2.72856407 |
46 | Abnormality of T cells (HP:0002843) | 2.69126922 |
47 | Periodontitis (HP:0000704) | 2.68046194 |
48 | Stomatitis (HP:0010280) | 2.66249974 |
49 | Meningitis (HP:0001287) | 2.64629166 |
50 | Gingivitis (HP:0000230) | 2.64067424 |
51 | Cellulitis (HP:0100658) | 2.63327687 |
52 | Thrombocytosis (HP:0001894) | 2.63066987 |
53 | Acute hepatic failure (HP:0006554) | 2.62069925 |
54 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.55837943 |
55 | Mucopolysacchariduria (HP:0008155) | 2.55837943 |
56 | Recurrent bronchitis (HP:0002837) | 2.55155540 |
57 | Recurrent cutaneous fungal infections (HP:0011370) | 2.52605676 |
58 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.52605676 |
59 | Epistaxis (HP:0000421) | 2.50654706 |
60 | Hemoptysis (HP:0002105) | 2.49466322 |
61 | Abnormality of eosinophils (HP:0001879) | 2.48682613 |
62 | Basal ganglia calcification (HP:0002135) | 2.48262609 |
63 | Inflammation of the large intestine (HP:0002037) | 2.44877425 |
64 | Gingival bleeding (HP:0000225) | 2.44306538 |
65 | Abnormal platelet volume (HP:0011876) | 2.44021037 |
66 | Poikilocytosis (HP:0004447) | 2.41713746 |
67 | Leukocytosis (HP:0001974) | 2.40109187 |
68 | Keratoconjunctivitis sicca (HP:0001097) | 2.39978987 |
69 | Gastrointestinal infarctions (HP:0005244) | 2.39679912 |
70 | Gastrointestinal inflammation (HP:0004386) | 2.36692655 |
71 | Abnormality of the nasal mucosa (HP:0000433) | 2.36489886 |
72 | Nasal polyposis (HP:0100582) | 2.34011178 |
73 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.30570856 |
74 | Osteolytic defects of the hand bones (HP:0009699) | 2.30570856 |
75 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.29351182 |
76 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.29351182 |
77 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.29351182 |
78 | Bruising susceptibility (HP:0000978) | 2.26606947 |
79 | Lymphoma (HP:0002665) | 2.25878909 |
80 | Abnormality of iron homeostasis (HP:0011031) | 2.24333095 |
81 | Dyschromatopsia (HP:0007641) | 2.21845164 |
82 | Eosinophilia (HP:0001880) | 2.18708410 |
83 | Submucous cleft hard palate (HP:0000176) | 2.17335780 |
84 | Menorrhagia (HP:0000132) | 2.17156979 |
85 | Abnormal platelet function (HP:0011869) | 2.16537124 |
86 | Impaired platelet aggregation (HP:0003540) | 2.16537124 |
87 | Increased mean platelet volume (HP:0011877) | 2.16156908 |
88 | Decreased central vision (HP:0007663) | 2.15469504 |
89 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.15309912 |
90 | Keratoconjunctivitis (HP:0001096) | 2.14946967 |
91 | B lymphocytopenia (HP:0010976) | 2.14107062 |
92 | Purpura (HP:0000979) | 2.13818001 |
93 | Chest pain (HP:0100749) | 2.13386978 |
94 | Severe combined immunodeficiency (HP:0004430) | 2.13295796 |
95 | Increased IgM level (HP:0003496) | 2.13153093 |
96 | Disinhibition (HP:0000734) | 2.12100666 |
97 | Myocardial infarction (HP:0001658) | 2.09873190 |
98 | Encephalitis (HP:0002383) | 2.08630831 |
99 | Lymphopenia (HP:0001888) | 2.08473121 |
100 | Albinism (HP:0001022) | 2.08302194 |
101 | Abnormality of the prostate (HP:0008775) | 2.08019832 |
102 | Osteomyelitis (HP:0002754) | 2.07473749 |
103 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.05443936 |
104 | Colitis (HP:0002583) | 2.03405027 |
105 | Spondylolisthesis (HP:0003302) | 2.02398333 |
106 | Hypergammaglobulinemia (HP:0010702) | 2.02086801 |
107 | IgA deficiency (HP:0002720) | 2.01961284 |
108 | Vertebral compression fractures (HP:0002953) | 2.01727764 |
109 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.99521314 |
110 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.99521314 |
111 | Abnormality of glycolipid metabolism (HP:0010969) | 1.99521314 |
112 | Panhypogammaglobulinemia (HP:0003139) | 1.98925077 |
113 | Thrombophlebitis (HP:0004418) | 1.98442102 |
114 | Renal cortical cysts (HP:0000803) | 1.97591653 |
115 | Increased IgE level (HP:0003212) | 1.96539864 |
116 | Granulocytopenia (HP:0001913) | 1.95843195 |
117 | Thyroiditis (HP:0100646) | 1.95048326 |
118 | Pulmonary embolism (HP:0002204) | 1.94642426 |
119 | Skin ulcer (HP:0200042) | 1.93892963 |
120 | Glomerulonephritis (HP:0000099) | 1.93830095 |
121 | Microcytic anemia (HP:0001935) | 1.93217331 |
122 | Episodic fever (HP:0001954) | 1.92018319 |
123 | Fatigue (HP:0012378) | 1.90884686 |
124 | Glomerulopathy (HP:0100820) | 1.89051857 |
125 | Hypoproteinemia (HP:0003075) | 1.88883049 |
126 | Joint swelling (HP:0001386) | 1.88826967 |
127 | Chronic diarrhea (HP:0002028) | 1.88669715 |
128 | IgG deficiency (HP:0004315) | 1.85425350 |
129 | Gangrene (HP:0100758) | 1.83738059 |
130 | Capillary hemangiomas (HP:0005306) | 1.80377355 |
131 | Polycythemia (HP:0001901) | 1.79815953 |
132 | Urticaria (HP:0001025) | 1.79370256 |
133 | Amaurosis fugax (HP:0100576) | 1.79153279 |
134 | Combined immunodeficiency (HP:0005387) | 1.78696451 |
135 | Aplastic anemia (HP:0001915) | 1.77727385 |
136 | Increased serum ferritin (HP:0003281) | 1.76946137 |
137 | Myelodysplasia (HP:0002863) | 1.75080940 |
138 | Amyloidosis (HP:0011034) | 1.74276798 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TXK | 3.37314924 |
2 | MAP4K1 | 3.34957713 |
3 | MAP3K14 | 3.05091102 |
4 | JAK3 | 3.00028382 |
5 | TYK2 | 2.50503239 |
6 | TBK1 | 2.43431563 |
7 | TGFBR2 | 2.41666310 |
8 | ZAP70 | 2.33299528 |
9 | BLK | 2.32158676 |
10 | IRAK4 | 2.26309166 |
11 | IRAK3 | 2.09619885 |
12 | STK10 | 1.99006954 |
13 | IKBKE | 1.97531435 |
14 | ERN1 | 1.96478152 |
15 | BMPR2 | 1.89457742 |
16 | BTK | 1.74202082 |
17 | IKBKB | 1.72788792 |
18 | TEC | 1.72670404 |
19 | RPS6KA4 | 1.71836873 |
20 | TRIM28 | 1.69751519 |
21 | ITK | 1.67379600 |
22 | MST4 | 1.61291074 |
23 | JAK1 | 1.60751091 |
24 | EPHB1 | 1.57405368 |
25 | EPHA3 | 1.57136447 |
26 | TAOK3 | 1.55255603 |
27 | KIT | 1.52936976 |
28 | CSK | 1.52715939 |
29 | NME2 | 1.46328183 |
30 | FGFR3 | 1.45349113 |
31 | NLK | 1.43426593 |
32 | TRIB3 | 1.42161969 |
33 | PIM2 | 1.41764918 |
34 | CHUK | 1.41111137 |
35 | LRRK2 | 1.40121323 |
36 | MAP3K3 | 1.37870435 |
37 | PIK3CG | 1.34292994 |
38 | KDR | 1.32629910 |
39 | BMPR1B | 1.32568217 |
40 | NEK9 | 1.32135983 |
41 | PKN2 | 1.30633055 |
42 | MAP2K3 | 1.30315365 |
43 | PIM1 | 1.21860975 |
44 | LCK | 1.21696585 |
45 | FGFR4 | 1.21401962 |
46 | SYK | 1.17602036 |
47 | MKNK1 | 1.12058611 |
48 | HCK | 1.10472581 |
49 | TGFBR1 | 1.09704603 |
50 | PLK4 | 1.09505400 |
51 | FGR | 1.08246468 |
52 | PTK2B | 1.07398022 |
53 | PRKCQ | 1.07184090 |
54 | FLT3 | 1.06204975 |
55 | RIPK4 | 1.04992175 |
56 | CSF1R | 1.04313082 |
57 | PTK6 | 1.03540097 |
58 | JAK2 | 1.01996929 |
59 | MYLK | 1.01569563 |
60 | RIPK1 | 1.01408585 |
61 | ADRBK2 | 1.01360147 |
62 | ACVR1B | 1.00004216 |
63 | SCYL2 | 0.99539832 |
64 | MARK3 | 0.92144324 |
65 | LYN | 0.88156043 |
66 | PINK1 | 0.88018480 |
67 | PAK4 | 0.86799484 |
68 | MAP3K5 | 0.81795502 |
69 | BCR | 0.81756274 |
70 | MAP3K12 | 0.81412628 |
71 | EIF2AK1 | 0.81116799 |
72 | MAPK7 | 0.79659452 |
73 | MAP3K10 | 0.79390020 |
74 | PASK | 0.78588931 |
75 | HIPK2 | 0.77041116 |
76 | IRAK1 | 0.73693548 |
77 | NEK2 | 0.71184464 |
78 | TRPM7 | 0.70247257 |
79 | CDK6 | 0.68641206 |
80 | PLK2 | 0.68396772 |
81 | FRK | 0.66208237 |
82 | CLK1 | 0.65688496 |
83 | RAF1 | 0.64356104 |
84 | BRSK2 | 0.63430525 |
85 | TTN | 0.62747122 |
86 | GRK6 | 0.62066750 |
87 | EEF2K | 0.61494578 |
88 | MAPKAPK2 | 0.61405375 |
89 | CSNK1G3 | 0.60539635 |
90 | MAP3K13 | 0.60527530 |
91 | STK3 | 0.60242315 |
92 | STK24 | 0.60102963 |
93 | MAP3K2 | 0.58495209 |
94 | MAP3K6 | 0.58443835 |
95 | TESK1 | 0.56809879 |
96 | PRKG2 | 0.56042568 |
97 | MATK | 0.53485747 |
98 | CDK8 | 0.52469471 |
99 | PDGFRB | 0.51973844 |
100 | EIF2AK3 | 0.51246184 |
101 | SIK3 | 0.49337920 |
102 | MKNK2 | 0.48755666 |
103 | ERBB3 | 0.47516843 |
104 | ABL1 | 0.47418010 |
105 | CDK4 | 0.46564042 |
106 | MAP2K7 | 0.46196550 |
107 | CSNK1G2 | 0.45818952 |
108 | ADRBK1 | 0.44869940 |
109 | MAP3K8 | 0.44831022 |
110 | MAP3K1 | 0.44699583 |
111 | MAP4K2 | 0.44241305 |
112 | CDK9 | 0.44019699 |
113 | FES | 0.43111784 |
114 | STK39 | 0.42830232 |
115 | EGFR | 0.42535045 |
116 | FYN | 0.39976614 |
117 | TIE1 | 0.39898406 |
118 | CAMKK2 | 0.39492860 |
119 | YES1 | 0.39026469 |
120 | NUAK1 | 0.38243079 |
121 | IGF1R | 0.38191981 |
122 | MAPK15 | 0.37546299 |
123 | TESK2 | 0.37066268 |
124 | MAPK11 | 0.37051125 |
125 | WNK4 | 0.36347890 |
126 | BMX | 0.36178211 |
127 | EIF2AK2 | 0.35473979 |
128 | PRKCD | 0.34794128 |
129 | STK4 | 0.34365304 |
130 | GRK7 | 0.33239811 |
131 | PDGFRA | 0.32928574 |
132 | RPS6KA5 | 0.32700969 |
133 | RPS6KB2 | 0.32562722 |
134 | RPS6KA6 | 0.32458169 |
135 | KSR1 | 0.32273530 |
136 | GRK1 | 0.31663748 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.82478644 |
2 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.34104658 |
3 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.28277489 |
4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.20844320 |
5 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.18377778 |
6 | Measles_Homo sapiens_hsa05162 | 2.13881766 |
7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.13062693 |
8 | Allograft rejection_Homo sapiens_hsa05330 | 2.06197120 |
9 | Legionellosis_Homo sapiens_hsa05134 | 2.05624264 |
10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.01389484 |
11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.99850857 |
12 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.94300258 |
13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.90650064 |
14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.85485884 |
15 | Pertussis_Homo sapiens_hsa05133 | 1.76302478 |
16 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.74710420 |
17 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.73266135 |
18 | Malaria_Homo sapiens_hsa05144 | 1.72482001 |
19 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.68914049 |
20 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.68304410 |
21 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.68037256 |
22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.67510805 |
23 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.56565746 |
24 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.54797601 |
25 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.54002018 |
26 | Tuberculosis_Homo sapiens_hsa05152 | 1.53046627 |
27 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.49153492 |
28 | Shigellosis_Homo sapiens_hsa05131 | 1.48678188 |
29 | Other glycan degradation_Homo sapiens_hsa00511 | 1.46773786 |
30 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.46734361 |
31 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.46124651 |
32 | Influenza A_Homo sapiens_hsa05164 | 1.44580083 |
33 | Asthma_Homo sapiens_hsa05310 | 1.40860731 |
34 | Lysosome_Homo sapiens_hsa04142 | 1.40416421 |
35 | Apoptosis_Homo sapiens_hsa04210 | 1.36703082 |
36 | Hepatitis B_Homo sapiens_hsa05161 | 1.33878769 |
37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.33210954 |
38 | Viral myocarditis_Homo sapiens_hsa05416 | 1.30474815 |
39 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.25631750 |
40 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.24960565 |
41 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.22530918 |
42 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.22524427 |
43 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.21595991 |
44 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.21299865 |
45 | Salmonella infection_Homo sapiens_hsa05132 | 1.19512294 |
46 | * Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.19028791 |
47 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.18269199 |
48 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.17294556 |
49 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.16603612 |
50 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.13892020 |
51 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.13508253 |
52 | Long-term depression_Homo sapiens_hsa04730 | 1.11651297 |
53 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.10157561 |
54 | Renin secretion_Homo sapiens_hsa04924 | 1.09905389 |
55 | Protein export_Homo sapiens_hsa03060 | 1.09713939 |
56 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.09207040 |
57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.04414166 |
58 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.04138389 |
59 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.01508258 |
60 | * Platelet activation_Homo sapiens_hsa04611 | 1.01381881 |
61 | Phagosome_Homo sapiens_hsa04145 | 0.99005780 |
62 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.98739596 |
63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.91619944 |
64 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.90757694 |
65 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.89773541 |
66 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.88338995 |
67 | Hepatitis C_Homo sapiens_hsa05160 | 0.87086339 |
68 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.86671942 |
69 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.85639700 |
70 | HTLV-I infection_Homo sapiens_hsa05166 | 0.84551894 |
71 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83473347 |
72 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.82690639 |
73 | Amoebiasis_Homo sapiens_hsa05146 | 0.81249983 |
74 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.79933395 |
75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.77750140 |
76 | Gap junction_Homo sapiens_hsa04540 | 0.77313941 |
77 | Salivary secretion_Homo sapiens_hsa04970 | 0.70847714 |
78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.67635586 |
79 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.67241625 |
80 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.60505383 |
81 | * Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.57803103 |
82 | Adherens junction_Homo sapiens_hsa04520 | 0.57268917 |
83 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.56842788 |
84 | Prostate cancer_Homo sapiens_hsa05215 | 0.56030772 |
85 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.55421473 |
86 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.55407719 |
87 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.54863376 |
88 | * Focal adhesion_Homo sapiens_hsa04510 | 0.54184607 |
89 | Colorectal cancer_Homo sapiens_hsa05210 | 0.52958864 |
90 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.52717466 |
91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.52460950 |
92 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.52323160 |
93 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.52314598 |
94 | DNA replication_Homo sapiens_hsa03030 | 0.51280009 |
95 | Thyroid cancer_Homo sapiens_hsa05216 | 0.50572830 |
96 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.50073727 |
97 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49337419 |
98 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.48021241 |
99 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.47450197 |
100 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47025552 |
101 | Endocytosis_Homo sapiens_hsa04144 | 0.46604268 |
102 | Insulin resistance_Homo sapiens_hsa04931 | 0.44513916 |
103 | Olfactory transduction_Homo sapiens_hsa04740 | 0.44197649 |
104 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.43614385 |
105 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.42666690 |
106 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.42609202 |
107 | Taste transduction_Homo sapiens_hsa04742 | 0.42393049 |
108 | * Ras signaling pathway_Homo sapiens_hsa04014 | 0.41008279 |
109 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.40727148 |
110 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.40348864 |
111 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.40021909 |
112 | * MAPK signaling pathway_Homo sapiens_hsa04010 | 0.39631358 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.39109831 |
114 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.38593633 |
115 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.35977472 |
116 | Cell cycle_Homo sapiens_hsa04110 | 0.35796893 |
117 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.35140564 |
118 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.34514966 |
119 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.33758341 |
120 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.33501926 |
121 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.33244867 |
122 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.33221005 |
123 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.33006556 |
124 | Prion diseases_Homo sapiens_hsa05020 | 0.32931503 |
125 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.32413785 |
126 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.32098077 |
127 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.29463483 |
128 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.28972561 |
129 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.28471626 |
130 | Pathways in cancer_Homo sapiens_hsa05200 | 0.27762705 |
131 | Melanoma_Homo sapiens_hsa05218 | 0.27155886 |