RAP2A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)5.62167142
2axon ensheathment in central nervous system (GO:0032291)5.62167142
3postsynaptic membrane organization (GO:0001941)5.21425462
4myelination (GO:0042552)4.96045679
5ensheathment of neurons (GO:0007272)4.95492740
6axon ensheathment (GO:0008366)4.95492740
7neurotransmitter-gated ion channel clustering (GO:0072578)4.81951704
8fatty acid elongation (GO:0030497)4.80484858
9locomotory exploration behavior (GO:0035641)4.51654084
10neuron cell-cell adhesion (GO:0007158)4.46800626
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.40106347
12negative regulation of neurotransmitter secretion (GO:0046929)4.38878937
13L-amino acid import (GO:0043092)4.31315466
14negative regulation of peptidyl-threonine phosphorylation (GO:0010801)4.20071176
15presynaptic membrane assembly (GO:0097105)4.18683436
16long-chain fatty acid biosynthetic process (GO:0042759)4.09280457
17sodium ion export (GO:0071436)4.06959104
18transmission of nerve impulse (GO:0019226)4.02409011
19cellular potassium ion homeostasis (GO:0030007)3.90895984
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.85081528
21negative regulation of neurotransmitter transport (GO:0051589)3.77577842
22membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.77379687
23regulation of synapse structural plasticity (GO:0051823)3.76779718
24cholesterol biosynthetic process (GO:0006695)3.71104531
25presynaptic membrane organization (GO:0097090)3.70471451
26substantia nigra development (GO:0021762)3.67820212
27amino acid import (GO:0043090)3.56492428
28synaptic vesicle maturation (GO:0016188)3.55601822
29neuronal action potential propagation (GO:0019227)3.55278100
30central nervous system projection neuron axonogenesis (GO:0021952)3.52485277
31dendrite morphogenesis (GO:0048813)3.49140108
32peripheral nervous system axon ensheathment (GO:0032292)3.48745242
33myelination in peripheral nervous system (GO:0022011)3.48745242
34auditory behavior (GO:0031223)3.46019835
35neuronal ion channel clustering (GO:0045161)3.45122535
36neuron recognition (GO:0008038)3.44490427
37negative regulation of axonogenesis (GO:0050771)3.41590842
38activated T cell proliferation (GO:0050798)3.41546676
39regulation of collateral sprouting (GO:0048670)3.40688788
40negative regulation of axon extension (GO:0030517)3.37825030
41positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.34865186
42glycerophospholipid catabolic process (GO:0046475)3.33960674
43regulation of synaptic vesicle exocytosis (GO:2000300)3.33950836
44dendritic spine morphogenesis (GO:0060997)3.32951444
45pyrimidine nucleobase catabolic process (GO:0006208)3.31038107
46exploration behavior (GO:0035640)3.30361565
47axonal fasciculation (GO:0007413)3.29722377
48synaptic vesicle exocytosis (GO:0016079)3.28707066
49response to auditory stimulus (GO:0010996)3.28621428
50sterol biosynthetic process (GO:0016126)3.27865642
51semaphorin-plexin signaling pathway (GO:0071526)3.25941123
52neuromuscular process controlling balance (GO:0050885)3.25608290
53regulation of short-term neuronal synaptic plasticity (GO:0048172)3.25220383
54adhesion of symbiont to host cell (GO:0044650)3.24338957
55virion attachment to host cell (GO:0019062)3.24338957
56cerebellar granule cell differentiation (GO:0021707)3.24065683
57positive regulation of dendritic spine morphogenesis (GO:0061003)3.24064948
58cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.23176044
59cerebral cortex radially oriented cell migration (GO:0021799)3.22891041
60cellular response to epinephrine stimulus (GO:0071872)3.21617941
61neurotransmitter uptake (GO:0001504)3.18757836
62nerve growth factor signaling pathway (GO:0038180)3.18597373
63cell communication by electrical coupling (GO:0010644)3.18567542
64positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.13587989
65positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.10909948
66neurotransmitter secretion (GO:0007269)3.07787390
67negative regulation of dendrite morphogenesis (GO:0050774)3.07357397
68glutamate secretion (GO:0014047)3.06776582
69cell migration in hindbrain (GO:0021535)3.06521386
70positive regulation of dendritic spine development (GO:0060999)3.05201332
71dermatan sulfate biosynthetic process (GO:0030208)3.03657703
72membrane assembly (GO:0071709)3.02364059
73peptidyl-tyrosine autophosphorylation (GO:0038083)3.01981989
74negative regulation of dendrite development (GO:2000171)3.01629968
75suckling behavior (GO:0001967)3.01278557
76ionotropic glutamate receptor signaling pathway (GO:0035235)3.01144412
77regulation of synaptic transmission, glutamatergic (GO:0051966)2.99850526
78response to redox state (GO:0051775)2.99179610
79potassium ion import (GO:0010107)2.98642071
80oligodendrocyte differentiation (GO:0048709)2.98435308
81regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.93804307
82response to epinephrine (GO:0071871)2.90433700
83mechanosensory behavior (GO:0007638)2.90127281
84gamma-aminobutyric acid signaling pathway (GO:0007214)2.88661620
85regulation of neurotransmitter secretion (GO:0046928)2.85705734
86protein localization to synapse (GO:0035418)2.85307075
87regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.85231724
88regulation of excitatory postsynaptic membrane potential (GO:0060079)2.84649561
89synaptic vesicle endocytosis (GO:0048488)2.80978247
90glutamate receptor signaling pathway (GO:0007215)2.80656367
91startle response (GO:0001964)2.80290694
92gamma-aminobutyric acid transport (GO:0015812)2.80281279
93positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.79366442
94long-term memory (GO:0007616)2.79306682
95vocalization behavior (GO:0071625)2.79280683
96positive regulation of actin filament depolymerization (GO:0030836)2.78382159
97cerebellar Purkinje cell differentiation (GO:0021702)2.77407994
98neuron remodeling (GO:0016322)2.76530671
99Notch signaling involved in heart development (GO:0061314)2.75431743
100import into cell (GO:0098657)2.74682938
101central nervous system neuron axonogenesis (GO:0021955)2.73548720
102adult walking behavior (GO:0007628)2.73471880
103cellular response to hepatocyte growth factor stimulus (GO:0035729)2.73402362
104response to hepatocyte growth factor (GO:0035728)2.73402362
105activation of protein kinase A activity (GO:0034199)2.73271717
106cellular sodium ion homeostasis (GO:0006883)2.72711901
107axon extension (GO:0048675)2.72277024
108layer formation in cerebral cortex (GO:0021819)2.70570314
109regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.70453206
110asymmetric protein localization (GO:0008105)2.69563617
111potassium ion homeostasis (GO:0055075)2.68986828
112nucleobase catabolic process (GO:0046113)2.67159603
113neurotransmitter transport (GO:0006836)2.65497698
114establishment of mitochondrion localization (GO:0051654)2.65411651
115cellular response to monoamine stimulus (GO:0071868)2.64438250
116cellular response to catecholamine stimulus (GO:0071870)2.64438250
117positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.64369233
118regulation of synaptic vesicle transport (GO:1902803)2.64040474
119establishment of nucleus localization (GO:0040023)2.63322868
120astrocyte development (GO:0014002)2.62591540
121apical protein localization (GO:0045176)2.62319053
122regulation of postsynaptic membrane potential (GO:0060078)2.61883594
123regulation of long-term neuronal synaptic plasticity (GO:0048169)2.61798890
124regulation of dendritic spine morphogenesis (GO:0061001)2.60449054
125positive regulation of synapse assembly (GO:0051965)2.60301917
126dermatan sulfate metabolic process (GO:0030205)2.58245253
127positive regulation of neurological system process (GO:0031646)2.57582952
128response to methylmercury (GO:0051597)2.57042285
129neuromuscular process (GO:0050905)2.56871545
130isoprenoid biosynthetic process (GO:0008299)2.56622847
131synaptic transmission, glutamatergic (GO:0035249)2.56328545
132regulation of axon extension involved in axon guidance (GO:0048841)2.56172758
133long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.55792930
134regulation of synaptic plasticity (GO:0048167)2.53975940
135positive regulation of membrane potential (GO:0045838)2.52874241
136embryonic retina morphogenesis in camera-type eye (GO:0060059)2.52708504
137regulation of glutamate receptor signaling pathway (GO:1900449)2.51474654
138regulation of neuronal synaptic plasticity (GO:0048168)2.50529808
139long-term synaptic potentiation (GO:0060291)2.50297240
140regulation of dendritic spine development (GO:0060998)2.48327931
141L-glutamate transport (GO:0015813)2.48292925
142regulation of voltage-gated calcium channel activity (GO:1901385)2.47335276
143synapse organization (GO:0050808)2.47321642
144adhesion of symbiont to host (GO:0044406)2.46330648
145neuron-neuron synaptic transmission (GO:0007270)2.45754988
146peripheral nervous system development (GO:0007422)2.45676807
147neural nucleus development (GO:0048857)2.44191126
148phosphatidylinositol 3-kinase signaling (GO:0014065)2.43086522
149acidic amino acid transport (GO:0015800)2.43044692
150eye photoreceptor cell differentiation (GO:0001754)2.40562849
151photoreceptor cell differentiation (GO:0046530)2.40562849
152response to catecholamine (GO:0071869)2.39540994
153response to monoamine (GO:0071867)2.39540994

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.41830044
2EZH2_22144423_ChIP-Seq_EOC_Human2.94246205
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.76110040
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.66871305
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.66723766
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.29989918
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.29989918
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.28857351
9* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.26297869
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.26010888
11AR_21572438_ChIP-Seq_LNCaP_Human2.25050079
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.21404754
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.19893172
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.16351449
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.15940441
16TAF15_26573619_Chip-Seq_HEK293_Human2.15823364
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.09974222
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.06713493
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.05942900
20DROSHA_22980978_ChIP-Seq_HELA_Human2.01909995
21CDX2_19796622_ChIP-Seq_MESCs_Mouse1.92467255
22EZH2_27294783_Chip-Seq_ESCs_Mouse1.92055521
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.90929110
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.89809078
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.89402260
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.83563379
27* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.81874574
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.80507854
29VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77599879
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.74215065
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.71857528
32TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.71407689
33WT1_19549856_ChIP-ChIP_CCG9911_Human1.69172258
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.66793201
35* REST_21632747_ChIP-Seq_MESCs_Mouse1.65523211
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.65182770
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.63709573
38NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.60453947
39SMAD3_21741376_ChIP-Seq_EPCs_Human1.59696000
40YAP1_20516196_ChIP-Seq_MESCs_Mouse1.57784857
41RARB_27405468_Chip-Seq_BRAIN_Mouse1.55094205
42* P300_19829295_ChIP-Seq_ESCs_Human1.54613485
43PIAS1_25552417_ChIP-Seq_VCAP_Human1.54520111
44* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.54046718
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.54040521
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.53249540
47ZNF217_24962896_ChIP-Seq_MCF-7_Human1.50502829
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50483015
49ER_23166858_ChIP-Seq_MCF-7_Human1.49060746
50SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.48294897
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44998638
52NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.43461884
53NRF2_20460467_ChIP-Seq_MEFs_Mouse1.43461884
54SMAD4_21799915_ChIP-Seq_A2780_Human1.42706402
55* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.42269073
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.38582061
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34907652
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34794126
59VDR_22108803_ChIP-Seq_LS180_Human1.33381618
60TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.32620122
61SMAD_19615063_ChIP-ChIP_OVARY_Human1.32080598
62AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31109893
63TRIM28_21343339_ChIP-Seq_HEK293_Human1.30382120
64TP53_16413492_ChIP-PET_HCT116_Human1.29873147
65SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28664680
66FUS_26573619_Chip-Seq_HEK293_Human1.28187659
67REST_18959480_ChIP-ChIP_MESCs_Mouse1.27735071
68STAT3_23295773_ChIP-Seq_U87_Human1.25221200
69EP300_21415370_ChIP-Seq_HL-1_Mouse1.24230389
70ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.24204790
71TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23508510
72TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22054573
73KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.21740767
74* SOX9_26525672_Chip-Seq_HEART_Mouse1.20335545
75SOX2_21211035_ChIP-Seq_LN229_Gbm1.20083242
76WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18728944
77CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.18471558
78SMAD3_21741376_ChIP-Seq_HESCs_Human1.15838083
79ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.15314503
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14405594
81KDM2B_26808549_Chip-Seq_REH_Human1.14388402
82NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.14238880
83TP53_18474530_ChIP-ChIP_U2OS_Human1.13929865
84CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.13921623
85* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.13833948
86TBX3_20139965_ChIP-Seq_MESCs_Mouse1.13600227
87AHR_22903824_ChIP-Seq_MCF-7_Human1.13371159
88ARNT_22903824_ChIP-Seq_MCF-7_Human1.12055497
89TBX3_20139965_ChIP-Seq_ESCs_Mouse1.10524295
90E2F1_18555785_Chip-Seq_ESCs_Mouse1.09747023
91STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.08799265
92TCF4_23295773_ChIP-Seq_U87_Human1.08079943
93RXR_22108803_ChIP-Seq_LS180_Human1.07631032
94GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07502008
95TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06144372
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.06066642
97AR_25329375_ChIP-Seq_VCAP_Human1.05879660
98RING1B_27294783_Chip-Seq_NPCs_Mouse1.05110104
99ZNF274_21170338_ChIP-Seq_K562_Hela1.04977483
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03633332
101* RUNX2_22187159_ChIP-Seq_PCA_Human1.03349753
102* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.99220761
103* RING1B_27294783_Chip-Seq_ESCs_Mouse0.99090482
104IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98927678
105RNF2_27304074_Chip-Seq_NSC_Mouse0.98201085
106* P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97689180
107NANOG_18555785_Chip-Seq_ESCs_Mouse0.96841698
108TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96805018
109NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96249890
110LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96067636
111* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94579174
112* AR_19668381_ChIP-Seq_PC3_Human0.94394276
113TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93611590
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.93611590
115FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.92853189
116BMI1_23680149_ChIP-Seq_NPCS_Mouse0.91992449
117CMYC_18555785_Chip-Seq_ESCs_Mouse0.91765893
118* JUN_21703547_ChIP-Seq_K562_Human0.90979611
119VDR_24787735_ChIP-Seq_THP-1_Human0.90784676
120* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.90698746
121SMAD4_21741376_ChIP-Seq_EPCs_Human0.90680415
122SMAD4_21741376_ChIP-Seq_HESCs_Human0.90475926

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.80233570
2MP0003880_abnormal_central_pattern4.78205728
3MP0000920_abnormal_myelination4.08661417
4MP0004270_analgesia3.71954573
5MP0003690_abnormal_glial_cell3.39951827
6MP0003635_abnormal_synaptic_transmissio3.07011021
7MP0002064_seizures2.93197708
8MP0000778_abnormal_nervous_system2.71587441
9MP0009745_abnormal_behavioral_response2.67674200
10MP0003329_amyloid_beta_deposits2.60437473
11MP0001486_abnormal_startle_reflex2.52337264
12MP0009046_muscle_twitch2.49497641
13MP0004742_abnormal_vestibular_system2.43205664
14MP0002272_abnormal_nervous_system2.42296071
15MP0002063_abnormal_learning/memory/cond2.41357627
16MP0004885_abnormal_endolymph2.29879077
17MP0001440_abnormal_grooming_behavior2.29377095
18MP0005171_absent_coat_pigmentation2.19660657
19MP0002572_abnormal_emotion/affect_behav2.19573170
20MP0003634_abnormal_glial_cell2.17714183
21MP0002734_abnormal_mechanical_nocicepti2.16284769
22MP0001968_abnormal_touch/_nociception2.00785180
23MP0003890_abnormal_embryonic-extraembry1.85712219
24MP0005423_abnormal_somatic_nervous1.85695807
25MP0001905_abnormal_dopamine_level1.85494323
26MP0005623_abnormal_meninges_morphology1.79193128
27MP0000604_amyloidosis1.75093856
28MP0003632_abnormal_nervous_system1.67525563
29MP0002733_abnormal_thermal_nociception1.63923256
30MP0002067_abnormal_sensory_capabilities1.59863032
31MP0001485_abnormal_pinna_reflex1.58823577
32MP0002882_abnormal_neuron_morphology1.55458169
33MP0002736_abnormal_nociception_after1.53220164
34MP0000955_abnormal_spinal_cord1.51440628
35MP0001529_abnormal_vocalization1.48866768
36MP0001970_abnormal_pain_threshold1.46763220
37MP0009780_abnormal_chondrocyte_physiolo1.42612816
38MP0000462_abnormal_digestive_system1.41813408
39MP0004924_abnormal_behavior1.41812211
40MP0005386_behavior/neurological_phenoty1.41812211
41MP0004142_abnormal_muscle_tone1.41204452
42MP0005409_darkened_coat_color1.41149890
43MP0002229_neurodegeneration1.40193510
44MP0002066_abnormal_motor_capabilities/c1.39702801
45MP0004858_abnormal_nervous_system1.38705348
46MP0002735_abnormal_chemical_nociception1.37516244
47MP0002184_abnormal_innervation1.34470976
48MP0004134_abnormal_chest_morphology1.33512875
49MP0005187_abnormal_penis_morphology1.33049718
50MP0003631_nervous_system_phenotype1.32052078
51MP0001501_abnormal_sleep_pattern1.29016528
52MP0002090_abnormal_vision1.27315724
53MP0008569_lethality_at_weaning1.27210793
54MP0003633_abnormal_nervous_system1.24111739
55MP0005167_abnormal_blood-brain_barrier1.22217954
56MP0003122_maternal_imprinting1.21997351
57MP0004811_abnormal_neuron_physiology1.21814110
58MP0001299_abnormal_eye_distance/1.20961835
59MP0003136_yellow_coat_color1.19607630
60MP0010234_abnormal_vibrissa_follicle1.16425672
61MP0001177_atelectasis1.13710875
62MP0002295_abnormal_pulmonary_circulatio1.13157950
63MP0002557_abnormal_social/conspecific_i1.12590385
64MP0002877_abnormal_melanocyte_morpholog1.10656330
65MP0002822_catalepsy1.10628429
66MP0003705_abnormal_hypodermis_morpholog1.07947417
67MP0002152_abnormal_brain_morphology1.06247254
68MP0003950_abnormal_plasma_membrane1.05284254
69MP0005551_abnormal_eye_electrophysiolog1.03473313
70MP0001984_abnormal_olfaction1.03441884
71MP0003787_abnormal_imprinting1.02645245
72MP0003172_abnormal_lysosome_physiology1.02129358
73MP0006276_abnormal_autonomic_nervous1.01692134
74MP0001963_abnormal_hearing_physiology1.01370105
75MP0002752_abnormal_somatic_nervous0.99094938
76MP0003119_abnormal_digestive_system0.98771945
77MP0004510_myositis0.98072583
78MP0004272_abnormal_basement_membrane0.95562541
79MP0005646_abnormal_pituitary_gland0.95134653
80MP0002909_abnormal_adrenal_gland0.93243031
81MP0005058_abnormal_lysosome_morphology0.91002255
82MP0008438_abnormal_cutaneous_collagen0.90848057
83MP0005248_abnormal_Harderian_gland0.90789636
84MP0010678_abnormal_skin_adnexa0.85946526
85MP0003938_abnormal_ear_development0.85560928
86MP0003075_altered_response_to0.85512809
87MP0005310_abnormal_salivary_gland0.84275071
88MP0002638_abnormal_pupillary_reflex0.83591170
89MP0000579_abnormal_nail_morphology0.81189222
90MP0003121_genomic_imprinting0.81131895
91MP0001879_abnormal_lymphatic_vessel0.81052356
92MP0002751_abnormal_autonomic_nervous0.79227258
93MP0003303_peritoneal_inflammation0.79030272
94MP0000516_abnormal_urinary_system0.78028383
95MP0005367_renal/urinary_system_phenotyp0.78028383
96MP0004145_abnormal_muscle_electrophysio0.77318439
97MP0008874_decreased_physiological_sensi0.77179564
98MP0005195_abnormal_posterior_eye0.76869815
99MP0000534_abnormal_ureter_morphology0.74875580
100MP0002081_perinatal_lethality0.74595787
101MP0000428_abnormal_craniofacial_morphol0.73084465
102MP0003935_abnormal_craniofacial_develop0.71866076
103MP0005388_respiratory_system_phenotype0.69723079
104MP0002133_abnormal_respiratory_system0.69723079
105MP0003937_abnormal_limbs/digits/tail_de0.68639243
106MP0002896_abnormal_bone_mineralization0.67496442
107MP0006082_CNS_inflammation0.65693628
108MP0003283_abnormal_digestive_organ0.65645915
109MP0005253_abnormal_eye_physiology0.65316142
110MP0001915_intracranial_hemorrhage0.64761590
111MP0000026_abnormal_inner_ear0.64171484
112MP0000383_abnormal_hair_follicle0.63596957
113MP0002233_abnormal_nose_morphology0.63179682
114MP0002697_abnormal_eye_size0.62096996
115MP0004215_abnormal_myocardial_fiber0.61855314
116MP0001502_abnormal_circadian_rhythm0.61204395
117MP0010769_abnormal_survival0.60442649
118MP0010770_preweaning_lethality0.60061256
119MP0000647_abnormal_sebaceous_gland0.59611319
120MP0002069_abnormal_eating/drinking_beha0.58000698
121MP0003385_abnormal_body_wall0.57868396
122MP0001943_abnormal_respiration0.57551980
123MP0003861_abnormal_nervous_system0.57498081
124MP0004185_abnormal_adipocyte_glucose0.57116248
125MP0000747_muscle_weakness0.55612313
126MP0003091_abnormal_cell_migration0.54791647
127MP0001851_eye_inflammation0.54787044
128MP0001661_extended_life_span0.52636776
129MP0000569_abnormal_digit_pigmentation0.51277248
130MP0009250_abnormal_appendicular_skeleto0.48005268
131MP0001346_abnormal_lacrimal_gland0.47729285
132MP0004130_abnormal_muscle_cell0.47087351
133MP0000537_abnormal_urethra_morphology0.46953840
134MP0005410_abnormal_fertilization0.46883186

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)5.79285306
2Degeneration of the lateral corticospinal tracts (HP:0002314)5.23312959
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.23312959
4Sensory axonal neuropathy (HP:0003390)4.97020623
5Cerebral inclusion bodies (HP:0100314)4.67040023
6Abnormality of the corticospinal tract (HP:0002492)4.65451359
7Atonic seizures (HP:0010819)4.24132011
8Supranuclear gaze palsy (HP:0000605)4.20650315
9Akinesia (HP:0002304)4.16367744
10Insidious onset (HP:0003587)4.02129043
11Termporal pattern (HP:0011008)4.02129043
12Focal motor seizures (HP:0011153)3.86556809
13Peripheral hypomyelination (HP:0007182)3.64484213
14Myokymia (HP:0002411)3.63591361
15Focal seizures (HP:0007359)3.47239306
16Intention tremor (HP:0002080)3.43848664
17Parakeratosis (HP:0001036)3.37338663
18Action tremor (HP:0002345)3.36849049
19Dysmetria (HP:0001310)3.23281180
20Papillary thyroid carcinoma (HP:0002895)3.21249039
21Spastic gait (HP:0002064)3.12262692
22Epileptic encephalopathy (HP:0200134)2.87004181
23Onion bulb formation (HP:0003383)2.83022458
24Urinary urgency (HP:0000012)2.81544178
25Cerebral hemorrhage (HP:0001342)2.80639324
26Limb dystonia (HP:0002451)2.72114219
27Cortical dysplasia (HP:0002539)2.69393310
28Impaired vibration sensation in the lower limbs (HP:0002166)2.69153621
29Inappropriate behavior (HP:0000719)2.63869965
30Dialeptic seizures (HP:0011146)2.60843796
31Mutism (HP:0002300)2.56120348
32Hyperventilation (HP:0002883)2.53370052
33Absence seizures (HP:0002121)2.53019053
34Truncal ataxia (HP:0002078)2.50277973
35Generalized myoclonic seizures (HP:0002123)2.50197973
36Relative macrocephaly (HP:0004482)2.49052844
37Pheochromocytoma (HP:0002666)2.47564014
38Fetal akinesia sequence (HP:0001989)2.45364445
39Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.44574407
40Scanning speech (HP:0002168)2.43876586
41Clumsiness (HP:0002312)2.43244876
42Small epiphyses (HP:0010585)2.42961671
43Progressive cerebellar ataxia (HP:0002073)2.40004528
44Disinhibition (HP:0000734)2.38772420
45Hemiplegia (HP:0002301)2.37651070
46Agnosia (HP:0010524)2.34239694
47Alacrima (HP:0000522)2.33611329
48Coronal craniosynostosis (HP:0004440)2.29807464
49Abnormality of binocular vision (HP:0011514)2.29709064
50Diplopia (HP:0000651)2.29709064
51Abnormality of glycolysis (HP:0004366)2.28095914
52Increased serum pyruvate (HP:0003542)2.28095914
53Broad-based gait (HP:0002136)2.26777812
54Abnormality of the parathyroid morphology (HP:0011766)2.24424914
55Split foot (HP:0001839)2.22937834
56Megalencephaly (HP:0001355)2.20853973
57Retinal dysplasia (HP:0007973)2.18655459
58Lower limb muscle weakness (HP:0007340)2.16954003
59Apathy (HP:0000741)2.16150761
60Hemiparesis (HP:0001269)2.15869003
61Slow saccadic eye movements (HP:0000514)2.15806586
62Spastic tetraparesis (HP:0001285)2.15421069
63Ankle clonus (HP:0011448)2.14912740
64Dysdiadochokinesis (HP:0002075)2.13675779
65Thickened helices (HP:0000391)2.13026287
66Generalized tonic-clonic seizures (HP:0002069)2.12882656
67Neuroendocrine neoplasm (HP:0100634)2.12767736
68Visual hallucinations (HP:0002367)2.11802875
69Progressive inability to walk (HP:0002505)2.11424429
70Abnormal eating behavior (HP:0100738)2.09486340
71Neoplasm of the peripheral nervous system (HP:0100007)2.08079884
72Diminished movement (HP:0002374)2.07805661
73Absent speech (HP:0001344)2.06568820
74Widely spaced teeth (HP:0000687)2.05294387
75Increased cerebral lipofuscin (HP:0011813)2.03794487
76Anteriorly placed anus (HP:0001545)2.03645030
77Abnormality of the ischium (HP:0003174)2.03224936
78Steppage gait (HP:0003376)1.98855989
79Aplasia involving bones of the extremities (HP:0009825)1.98851572
80Aplasia involving bones of the upper limbs (HP:0009823)1.98851572
81Aplasia of the phalanges of the hand (HP:0009802)1.98851572
82Gaze-evoked nystagmus (HP:0000640)1.98815313
83Urinary bladder sphincter dysfunction (HP:0002839)1.98810435
84Protruding tongue (HP:0010808)1.98266258
85Thyroid carcinoma (HP:0002890)1.98254069
86Abnormal social behavior (HP:0012433)1.97727097
87Impaired social interactions (HP:0000735)1.97727097
88Cutaneous finger syndactyly (HP:0010554)1.96089459
89Blue irides (HP:0000635)1.95911533
90Hammertoe (HP:0001765)1.95560025
91Polyphagia (HP:0002591)1.94922251
92Pulmonic stenosis (HP:0001642)1.94808360
93Aqueductal stenosis (HP:0002410)1.94767823
94Cerebral hypomyelination (HP:0006808)1.93619177
95Abnormality of salivation (HP:0100755)1.93031853
96Insomnia (HP:0100785)1.92563873
97Lower limb asymmetry (HP:0100559)1.92383502
98Drooling (HP:0002307)1.92021004
99Excessive salivation (HP:0003781)1.92021004
100Increased neuronal autofluorescent lipopigment (HP:0002074)1.91734290
101Cupped ear (HP:0000378)1.91194031
102Premature skin wrinkling (HP:0100678)1.90347421
103Arterial tortuosity (HP:0005116)1.89528961
104Partial agenesis of the corpus callosum (HP:0001338)1.89450639
105Poor eye contact (HP:0000817)1.88893098
106Thick nail (HP:0001805)1.88503652
107Morphological abnormality of the pyramidal tract (HP:0002062)1.87337416
108Cutaneous syndactyly (HP:0012725)1.86927744
109Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.86771374
110Diminished motivation (HP:0000745)1.86268891
111Febrile seizures (HP:0002373)1.86070108
112Anomalous pulmonary venous return (HP:0010772)1.85726757
113Vertebral arch anomaly (HP:0008438)1.85527289
114Abnormal auditory evoked potentials (HP:0006958)1.85156729
115Increased circulating renin level (HP:0000848)1.83402868
116Overgrowth (HP:0001548)1.82546569
117Epiphyseal dysplasia (HP:0002656)1.80253370
118Large earlobe (HP:0009748)1.77767554
119Depression (HP:0000716)1.77498650
120Ulnar claw (HP:0001178)1.77476150
121Postural instability (HP:0002172)1.76525770
122Neuronal loss in central nervous system (HP:0002529)1.76292804
123Chin dimple (HP:0010751)1.76176068
124Transitional cell carcinoma of the bladder (HP:0006740)1.75681148
125Hypoplasia of the corpus callosum (HP:0002079)1.75331020
126Decreased lacrimation (HP:0000633)1.74928506
127Infantile muscular hypotonia (HP:0008947)1.74676400
128Bowel incontinence (HP:0002607)1.74205105
129Spastic paraparesis (HP:0002313)1.74179285
130Buphthalmos (HP:0000557)1.72738789
131Overriding aorta (HP:0002623)1.72670196
132Abnormality of the lower motor neuron (HP:0002366)1.71832336
133Postural tremor (HP:0002174)1.71154112
134Mild short stature (HP:0003502)1.70333977
135Abnormality of the vitreous humor (HP:0004327)1.70180948
136Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.69233862
137Abnormal large intestine physiology (HP:0012700)1.68646861
138Stereotypic behavior (HP:0000733)1.67960682
139Abnormality of the periventricular white matter (HP:0002518)1.67766070
140Abnormality of the pulmonary veins (HP:0011718)1.67702989
141Gait ataxia (HP:0002066)1.66585546
142Deeply set eye (HP:0000490)1.66247577
143Bladder carcinoma (HP:0002862)1.65539085
144Bladder neoplasm (HP:0009725)1.65539085
145Clonus (HP:0002169)1.65009182
146Spastic paraplegia (HP:0001258)1.64997459
147Impaired vibratory sensation (HP:0002495)1.64492554
148Ankyloglossia (HP:0010296)1.63820441
149Difficulty running (HP:0009046)1.63334942
150Vascular tortuosity (HP:0004948)1.62630256
151Arnold-Chiari malformation (HP:0002308)1.62424444
152Type II lissencephaly (HP:0007260)1.62313198
153Lower limb amyotrophy (HP:0007210)1.61585918
154Heterochromia iridis (HP:0001100)1.61126046

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.94874764
2TNIK3.84673093
3OXSR13.36761853
4EPHA42.63128435
5EPHB12.59381582
6MARK12.57117959
7MAP3K92.31284800
8TYRO32.27960405
9BCR2.23525972
10PAK62.03331385
11PKN12.00915290
12NTRK32.00368484
13WNK41.97039021
14NTRK11.95599650
15FGR1.88006608
16FES1.76541808
17CDK191.73781873
18UHMK11.69967848
19MAPK131.67424552
20PRPF4B1.66924492
21KSR21.59804623
22SGK21.56810049
23FGFR21.56328903
24PDGFRA1.55646326
25ICK1.55470006
26MINK11.53517143
27CASK1.51974867
28PBK1.37912667
29PNCK1.37749517
30CCNB11.34420815
31WNK11.32086461
32IRAK21.30040856
33MET1.28373626
34CSNK1G31.24821102
35CSNK1G21.24699029
36TSSK61.24441465
37PLK21.22162904
38CDK51.18864989
39SGK31.18731731
40RIPK41.18007840
41CSNK1A1L1.17248466
42MAP3K21.16508290
43MKNK21.16237891
44MAP3K41.15730300
45ROCK21.14162735
46PAK31.13473678
47LIMK11.13092915
48NTRK21.10065282
49YES11.09381650
50NEK61.08674288
51PRKD31.03204027
52ARAF1.02450545
53CDK141.02348852
54ERBB31.01964489
55DAPK20.99799085
56MST40.93064171
57MAP3K100.92744022
58CAMK2B0.91418239
59PTK2B0.89828242
60CSNK1G10.89740269
61CAMK2A0.89459641
62NEK90.86575012
63IRAK10.85992569
64GRK50.85458605
65MAP3K130.83797734
66KSR10.83372519
67DMPK0.82879160
68MAP2K70.80283367
69FYN0.79933692
70CAMK2D0.79845529
71CDK150.79633224
72WNK30.79261679
73MKNK10.78926166
74PRKCQ0.78300892
75MAP2K40.78255445
76CDK180.77673816
77PDGFRB0.70662731
78RET0.70326735
79TAF10.70058380
80ERBB40.69424452
81PRKCE0.68004076
82SGK4940.67491026
83SGK2230.67491026
84CDK11A0.67140642
85PDPK10.66876202
86ROCK10.65508822
87CAMKK10.63947739
88STK38L0.61887142
89MAPK100.61475752
90MARK20.61048247
91DYRK20.60938125
92CAMK1D0.60827989
93STK110.60773721
94DYRK1A0.60139380
95ABL20.59539541
96PHKG20.59400795
97PHKG10.59400795
98ALK0.58793515
99PRKCG0.57356177
100RAF10.57204228
101CAMK1G0.56292816
102CLK10.55588275
103PLK30.54562232
104BRD40.54412918
105BRAF0.54372541
106STK240.53886806
107MAPKAPK50.53696030
108PINK10.53541901
109IRAK40.52763854
110TIE10.52687462
111WEE10.52185284
112MAPK120.52043333
113CAMKK20.50985596
114CSK0.50397035
115PTK20.46783591
116CDK30.45903469
117CAMK2G0.45625635
118PRKCH0.45590369
119PDK10.44794331
120BMX0.43039122
121BMPR20.42292465
122SIK20.40882195
123SGK10.40830411
124CAMK10.40126527
125RIPK10.39797995
126CAMK40.39399976
127LATS20.38673199
128DDR20.38306161
129PRKG10.37996665
130EPHB20.37889229
131ACVR1B0.37767954
132MOS0.37217598
133INSR0.37025574
134MAP3K120.36885388

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.63733839
2Steroid biosynthesis_Homo sapiens_hsa001003.17572224
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.78231527
4Axon guidance_Homo sapiens_hsa043602.31025358
5Glutamatergic synapse_Homo sapiens_hsa047242.11474434
6Synaptic vesicle cycle_Homo sapiens_hsa047212.04084374
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.93501185
8Nicotine addiction_Homo sapiens_hsa050331.89326169
9GABAergic synapse_Homo sapiens_hsa047271.85822511
10Ether lipid metabolism_Homo sapiens_hsa005651.82611298
11Fatty acid elongation_Homo sapiens_hsa000621.78297515
12Collecting duct acid secretion_Homo sapiens_hsa049661.77561455
13Serotonergic synapse_Homo sapiens_hsa047261.71180971
14Long-term depression_Homo sapiens_hsa047301.70062812
15Morphine addiction_Homo sapiens_hsa050321.62009446
16Long-term potentiation_Homo sapiens_hsa047201.62000800
17Circadian entrainment_Homo sapiens_hsa047131.60789488
18Cholinergic synapse_Homo sapiens_hsa047251.57536241
19Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.50878689
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.46453022
21Salivary secretion_Homo sapiens_hsa049701.44380417
22Dopaminergic synapse_Homo sapiens_hsa047281.43994650
23Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.39203536
24Renal cell carcinoma_Homo sapiens_hsa052111.35836814
25Vibrio cholerae infection_Homo sapiens_hsa051101.26904421
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.25779852
27Rheumatoid arthritis_Homo sapiens_hsa053231.21412735
28Renin secretion_Homo sapiens_hsa049241.21065299
29Gastric acid secretion_Homo sapiens_hsa049711.17805806
30Phospholipase D signaling pathway_Homo sapiens_hsa040721.17549855
31Endometrial cancer_Homo sapiens_hsa052131.16871541
32Olfactory transduction_Homo sapiens_hsa047401.14449301
33Oxytocin signaling pathway_Homo sapiens_hsa049211.12734500
34Dorso-ventral axis formation_Homo sapiens_hsa043201.08705424
35Neurotrophin signaling pathway_Homo sapiens_hsa047221.05666556
36Amphetamine addiction_Homo sapiens_hsa050311.05501073
37Sphingolipid signaling pathway_Homo sapiens_hsa040711.04771424
38Colorectal cancer_Homo sapiens_hsa052101.03748600
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.03367346
40GnRH signaling pathway_Homo sapiens_hsa049121.03075359
41Gap junction_Homo sapiens_hsa045401.03072630
42ErbB signaling pathway_Homo sapiens_hsa040121.02588633
43Oxidative phosphorylation_Homo sapiens_hsa001901.01932480
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00295571
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.00095741
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.98420209
47Hippo signaling pathway_Homo sapiens_hsa043900.98131279
48Adherens junction_Homo sapiens_hsa045200.96322357
49Phagosome_Homo sapiens_hsa041450.95309839
50Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.94881295
51Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.92658019
52Endocytosis_Homo sapiens_hsa041440.91124114
53Ras signaling pathway_Homo sapiens_hsa040140.90587597
54Alzheimers disease_Homo sapiens_hsa050100.90509093
55Thyroid hormone synthesis_Homo sapiens_hsa049180.89382284
56Oocyte meiosis_Homo sapiens_hsa041140.89010597
57Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.88575026
58Thyroid hormone signaling pathway_Homo sapiens_hsa049190.88328506
59Choline metabolism in cancer_Homo sapiens_hsa052310.88133012
60Glioma_Homo sapiens_hsa052140.87629780
61Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.87617942
62Wnt signaling pathway_Homo sapiens_hsa043100.87494648
63Butanoate metabolism_Homo sapiens_hsa006500.87369191
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.86466199
65Sphingolipid metabolism_Homo sapiens_hsa006000.82560856
66Sulfur metabolism_Homo sapiens_hsa009200.82235605
67Aldosterone synthesis and secretion_Homo sapiens_hsa049250.81056416
68Vitamin B6 metabolism_Homo sapiens_hsa007500.81030320
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.80931744
70Estrogen signaling pathway_Homo sapiens_hsa049150.80308638
71Cocaine addiction_Homo sapiens_hsa050300.79199124
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78384827
73Prolactin signaling pathway_Homo sapiens_hsa049170.78270840
74Inositol phosphate metabolism_Homo sapiens_hsa005620.77836809
75AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.77032409
76Prion diseases_Homo sapiens_hsa050200.75722473
77cAMP signaling pathway_Homo sapiens_hsa040240.75667286
78Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75001629
79Calcium signaling pathway_Homo sapiens_hsa040200.73642031
80Alcoholism_Homo sapiens_hsa050340.70342418
81Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69211582
82Salmonella infection_Homo sapiens_hsa051320.69125837
83Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68768837
84Tight junction_Homo sapiens_hsa045300.67843637
85Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67831212
86Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.67611398
87MicroRNAs in cancer_Homo sapiens_hsa052060.67111915
88Chemokine signaling pathway_Homo sapiens_hsa040620.66416583
89Lysosome_Homo sapiens_hsa041420.66029895
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65498753
91VEGF signaling pathway_Homo sapiens_hsa043700.65433353
92Ovarian steroidogenesis_Homo sapiens_hsa049130.65304144
93Taste transduction_Homo sapiens_hsa047420.65296287
94Circadian rhythm_Homo sapiens_hsa047100.64832963
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64438454
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63509228
97Insulin secretion_Homo sapiens_hsa049110.63362727
98Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63353937
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.63131080
100Chronic myeloid leukemia_Homo sapiens_hsa052200.62036339
101Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61719160
102MAPK signaling pathway_Homo sapiens_hsa040100.61060580
103Pancreatic secretion_Homo sapiens_hsa049720.60154726
104Melanogenesis_Homo sapiens_hsa049160.59965868
105Type II diabetes mellitus_Homo sapiens_hsa049300.59908833
106mTOR signaling pathway_Homo sapiens_hsa041500.59161201
107Hedgehog signaling pathway_Homo sapiens_hsa043400.58980500
108TGF-beta signaling pathway_Homo sapiens_hsa043500.58395732
109Bile secretion_Homo sapiens_hsa049760.57033568
110HIF-1 signaling pathway_Homo sapiens_hsa040660.56795762
111Central carbon metabolism in cancer_Homo sapiens_hsa052300.55756445
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55754253
113Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54909789
114Non-small cell lung cancer_Homo sapiens_hsa052230.54530798
115Cardiac muscle contraction_Homo sapiens_hsa042600.54201128
116ECM-receptor interaction_Homo sapiens_hsa045120.54070777
117Focal adhesion_Homo sapiens_hsa045100.52913211
118Platelet activation_Homo sapiens_hsa046110.52042635
119Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50943575
120cGMP-PKG signaling pathway_Homo sapiens_hsa040220.47996053
121Rap1 signaling pathway_Homo sapiens_hsa040150.47946884
122Shigellosis_Homo sapiens_hsa051310.47257744
123Fatty acid biosynthesis_Homo sapiens_hsa000610.46964780
124Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45568277
125Malaria_Homo sapiens_hsa051440.43469305
126Amoebiasis_Homo sapiens_hsa051460.42079237
127Dilated cardiomyopathy_Homo sapiens_hsa054140.41384368
128Parkinsons disease_Homo sapiens_hsa050120.40770643
129Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39145364
130African trypanosomiasis_Homo sapiens_hsa051430.39130406
131Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.38846317
132Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35653248
133Phototransduction_Homo sapiens_hsa047440.34600710
134Proteoglycans in cancer_Homo sapiens_hsa052050.34304613

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