Rank | Gene Set | Z-score |
---|---|---|
1 | DNA deamination (GO:0045006) | 5.24472207 |
2 | ribosomal small subunit assembly (GO:0000028) | 4.84584240 |
3 | proteasome assembly (GO:0043248) | 4.54914815 |
4 | nucleobase biosynthetic process (GO:0046112) | 4.51454966 |
5 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.34589250 |
6 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.31984000 |
7 | purine nucleobase biosynthetic process (GO:0009113) | 4.21304375 |
8 | DNA strand elongation (GO:0022616) | 4.20258302 |
9 | ribosomal large subunit biogenesis (GO:0042273) | 4.14638052 |
10 | formation of translation preinitiation complex (GO:0001731) | 4.08690546 |
11 | DNA double-strand break processing (GO:0000729) | 4.05930300 |
12 | telomere maintenance via recombination (GO:0000722) | 3.95648986 |
13 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.86993094 |
14 | protein neddylation (GO:0045116) | 3.85336368 |
15 | DNA replication initiation (GO:0006270) | 3.77315984 |
16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.76540608 |
17 | IMP biosynthetic process (GO:0006188) | 3.73300099 |
18 | mitotic recombination (GO:0006312) | 3.70086186 |
19 | respiratory chain complex IV assembly (GO:0008535) | 3.69088524 |
20 | CENP-A containing nucleosome assembly (GO:0034080) | 3.67871493 |
21 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.62862346 |
22 | maturation of SSU-rRNA (GO:0030490) | 3.62516745 |
23 | chromatin remodeling at centromere (GO:0031055) | 3.60981952 |
24 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.60153605 |
25 | DNA replication checkpoint (GO:0000076) | 3.57443246 |
26 | rRNA modification (GO:0000154) | 3.54851731 |
27 | viral mRNA export from host cell nucleus (GO:0046784) | 3.54598693 |
28 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.53259280 |
29 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.50258933 |
30 | telomere maintenance via telomere lengthening (GO:0010833) | 3.49298205 |
31 | DNA unwinding involved in DNA replication (GO:0006268) | 3.47616283 |
32 | establishment of integrated proviral latency (GO:0075713) | 3.46496851 |
33 | replication fork processing (GO:0031297) | 3.45347416 |
34 | ribosome biogenesis (GO:0042254) | 3.44918648 |
35 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.43137332 |
36 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.42730804 |
37 | ribosome assembly (GO:0042255) | 3.41602315 |
38 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.40733478 |
39 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.40733478 |
40 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.39432969 |
41 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.39432969 |
42 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.39432969 |
43 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.38857887 |
44 | pseudouridine synthesis (GO:0001522) | 3.37702953 |
45 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.35731455 |
46 | negative regulation of ligase activity (GO:0051352) | 3.35731455 |
47 | cullin deneddylation (GO:0010388) | 3.34298855 |
48 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.31618148 |
49 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.31359153 |
50 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.31359153 |
51 | cotranslational protein targeting to membrane (GO:0006613) | 3.30199528 |
52 | viral transcription (GO:0019083) | 3.29274224 |
53 | protein deneddylation (GO:0000338) | 3.28630953 |
54 | protein-cofactor linkage (GO:0018065) | 3.28514042 |
55 | translational termination (GO:0006415) | 3.28468749 |
56 | maturation of 5.8S rRNA (GO:0000460) | 3.27871702 |
57 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.26951849 |
58 | oxidative phosphorylation (GO:0006119) | 3.26936711 |
59 | protein targeting to ER (GO:0045047) | 3.25609884 |
60 | translational elongation (GO:0006414) | 3.22111120 |
61 | spliceosomal snRNP assembly (GO:0000387) | 3.22102482 |
62 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.21889422 |
63 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.21084920 |
64 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.20397420 |
65 | ribosomal small subunit biogenesis (GO:0042274) | 3.20294893 |
66 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.19817847 |
67 | 7-methylguanosine mRNA capping (GO:0006370) | 3.19038959 |
68 | protein localization to endoplasmic reticulum (GO:0070972) | 3.16485591 |
69 | DNA replication-independent nucleosome organization (GO:0034724) | 3.15926003 |
70 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.15926003 |
71 | IMP metabolic process (GO:0046040) | 3.14057219 |
72 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.13911754 |
73 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.13911754 |
74 | rRNA processing (GO:0006364) | 3.13033454 |
75 | mitotic metaphase plate congression (GO:0007080) | 3.12042238 |
76 | RNA capping (GO:0036260) | 3.11298745 |
77 | 7-methylguanosine RNA capping (GO:0009452) | 3.11298745 |
78 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.11273406 |
79 | kinetochore organization (GO:0051383) | 3.10786925 |
80 | translation (GO:0006412) | 3.10676780 |
81 | resolution of meiotic recombination intermediates (GO:0000712) | 3.10672239 |
82 | DNA damage response, detection of DNA damage (GO:0042769) | 3.10088767 |
83 | rRNA methylation (GO:0031167) | 3.09994052 |
84 | protein localization to kinetochore (GO:0034501) | 3.07682904 |
85 | protein complex biogenesis (GO:0070271) | 3.07321562 |
86 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.06767040 |
87 | COPI coating of Golgi vesicle (GO:0048205) | 3.05135171 |
88 | Golgi transport vesicle coating (GO:0048200) | 3.05135171 |
89 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.04712607 |
90 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.04678825 |
91 | cell cycle G1/S phase transition (GO:0044843) | 3.04678825 |
92 | cellular component biogenesis (GO:0044085) | 3.04141657 |
93 | translational initiation (GO:0006413) | 3.03782109 |
94 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.03327637 |
95 | kinetochore assembly (GO:0051382) | 3.02732895 |
96 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.01904059 |
97 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.00883314 |
98 | rRNA metabolic process (GO:0016072) | 3.00737219 |
99 | cytochrome complex assembly (GO:0017004) | 3.00481992 |
100 | regulation of DNA endoreduplication (GO:0032875) | 3.00137678 |
101 | termination of RNA polymerase I transcription (GO:0006363) | 2.99262243 |
102 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.99030429 |
103 | metallo-sulfur cluster assembly (GO:0031163) | 2.98171284 |
104 | iron-sulfur cluster assembly (GO:0016226) | 2.98171284 |
105 | histone exchange (GO:0043486) | 2.97899104 |
106 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.95288828 |
107 | lactate metabolic process (GO:0006089) | 2.94978750 |
108 | intraciliary transport (GO:0042073) | 2.94302982 |
109 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.94192161 |
110 | positive regulation of ligase activity (GO:0051351) | 2.92684471 |
111 | telomere organization (GO:0032200) | 2.90235696 |
112 | telomere maintenance (GO:0000723) | 2.89586934 |
113 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.89358085 |
114 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.89358085 |
115 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.88257143 |
116 | NADH dehydrogenase complex assembly (GO:0010257) | 2.88257143 |
117 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.88257143 |
118 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.87159514 |
119 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.86852535 |
120 | mitotic nuclear envelope disassembly (GO:0007077) | 2.86719995 |
121 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.86427496 |
122 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.86427496 |
123 | regulation of helicase activity (GO:0051095) | 2.85615132 |
124 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.84337817 |
125 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.84337817 |
126 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.83462899 |
127 | non-recombinational repair (GO:0000726) | 2.83462899 |
128 | tRNA methylation (GO:0030488) | 2.83357184 |
129 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.83263558 |
130 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.83215195 |
131 | response to pheromone (GO:0019236) | 2.82712564 |
132 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.81515912 |
133 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.71510998 |
134 | DNA ligation (GO:0006266) | 2.69929133 |
135 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.67602473 |
136 | recombinational repair (GO:0000725) | 2.66213098 |
137 | branched-chain amino acid catabolic process (GO:0009083) | 2.65712265 |
138 | metaphase plate congression (GO:0051310) | 2.62766895 |
139 | double-strand break repair via homologous recombination (GO:0000724) | 2.62363191 |
140 | ATP synthesis coupled proton transport (GO:0015986) | 2.60524766 |
141 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.60524766 |
142 | positive regulation of mitochondrial fission (GO:0090141) | 2.58653639 |
143 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.56635262 |
144 | anterograde synaptic vesicle transport (GO:0048490) | 2.56061358 |
145 | negative regulation of DNA recombination (GO:0045910) | 2.55216920 |
146 | regulation of glucokinase activity (GO:0033131) | 2.54683276 |
147 | regulation of hexokinase activity (GO:1903299) | 2.54683276 |
148 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.54521412 |
149 | cholesterol biosynthetic process (GO:0006695) | 2.52883306 |
150 | histone mRNA metabolic process (GO:0008334) | 2.52579339 |
151 | histone H2A acetylation (GO:0043968) | 2.52305703 |
152 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.51509448 |
153 | spindle checkpoint (GO:0031577) | 2.51431791 |
154 | nucleobase catabolic process (GO:0046113) | 2.50390750 |
155 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.45843394 |
156 | postreplication repair (GO:0006301) | 2.45221032 |
157 | presynaptic membrane assembly (GO:0097105) | 2.41891955 |
158 | mitotic spindle checkpoint (GO:0071174) | 2.41472995 |
159 | aldehyde catabolic process (GO:0046185) | 2.41436785 |
160 | mitochondrial RNA metabolic process (GO:0000959) | 2.41240107 |
161 | regulation of meiosis I (GO:0060631) | 2.40810629 |
162 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.40494542 |
163 | termination of RNA polymerase III transcription (GO:0006386) | 2.40494542 |
164 | sterol biosynthetic process (GO:0016126) | 2.40310035 |
165 | cilium morphogenesis (GO:0060271) | 2.39630369 |
166 | organelle disassembly (GO:1903008) | 2.38896023 |
167 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.38384542 |
168 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.38384542 |
169 | isotype switching (GO:0045190) | 2.38384542 |
170 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 2.37343431 |
171 | protein K11-linked ubiquitination (GO:0070979) | 2.36964704 |
172 | nonmotile primary cilium assembly (GO:0035058) | 2.35670487 |
173 | chaperone-mediated protein transport (GO:0072321) | 2.35320322 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.97571100 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.53997993 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.29126649 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.75094746 |
5 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.67449388 |
6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.66882881 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.60230533 |
8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.27975098 |
9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.20493534 |
10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.19030615 |
11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.12575199 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.10719662 |
13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.06379547 |
14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.01285326 |
15 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.00943001 |
16 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.90050305 |
17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.78311480 |
18 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.77547162 |
19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.60427747 |
20 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.54217724 |
21 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.47255292 |
22 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.45949757 |
23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.45252403 |
24 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.39348220 |
25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.36900441 |
26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.36892817 |
27 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.34722844 |
28 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.33520024 |
29 | EWS_26573619_Chip-Seq_HEK293_Human | 2.32638179 |
30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.31854558 |
31 | FUS_26573619_Chip-Seq_HEK293_Human | 2.30551666 |
32 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.30543273 |
33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.27935448 |
34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.21719562 |
35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.19099076 |
36 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.15792754 |
37 | * GABP_19822575_ChIP-Seq_HepG2_Human | 2.15454827 |
38 | VDR_22108803_ChIP-Seq_LS180_Human | 2.11380733 |
39 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.10946364 |
40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.08699869 |
41 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.07725261 |
42 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.07011931 |
43 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.96794770 |
44 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.94533019 |
45 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.92714779 |
46 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.87290282 |
47 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.85534346 |
48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.83436265 |
49 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.83342845 |
50 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.82714947 |
51 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.80860217 |
52 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80106893 |
53 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.79921139 |
54 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.79902736 |
55 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.79590297 |
56 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.79275441 |
57 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.78392639 |
58 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.76893789 |
59 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.75536418 |
60 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.75264163 |
61 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.74924477 |
62 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.72290674 |
63 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.70295025 |
64 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.70005476 |
65 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67361676 |
66 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.63191900 |
67 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62709145 |
68 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.59680204 |
69 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.57387147 |
70 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.54919800 |
71 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.52172421 |
72 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.50546761 |
73 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.48031405 |
74 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46932618 |
75 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.45316739 |
76 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.44430503 |
77 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.43795259 |
78 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.36742872 |
79 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.35755750 |
80 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.32897741 |
81 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.32337108 |
82 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.30864588 |
83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.30517707 |
84 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.30165143 |
85 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28580590 |
86 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.28074086 |
87 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.27958524 |
88 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26935922 |
89 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.26709388 |
90 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.23862486 |
91 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.23277505 |
92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.22223444 |
93 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.21761571 |
94 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.20120813 |
95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.19930614 |
96 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.19930614 |
97 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.17564269 |
98 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.16758683 |
99 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.15759709 |
100 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.15596590 |
101 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.14982609 |
102 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.13403347 |
103 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.13187994 |
104 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.12718356 |
105 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.11871233 |
106 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.11076721 |
107 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10969950 |
108 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09581980 |
109 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.05842235 |
110 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.04618119 |
111 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.04569700 |
112 | GATA1_22025678_ChIP-Seq_K562_Human | 1.03673671 |
113 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.03264959 |
114 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03155659 |
115 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02801156 |
116 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02557158 |
117 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.01947742 |
118 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.01947742 |
119 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01782164 |
120 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.01018040 |
121 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.00883795 |
122 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.00883133 |
123 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.00867542 |
124 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.00605306 |
125 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.00579865 |
126 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.00281981 |
127 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99486240 |
128 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.98797868 |
129 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.98494874 |
130 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.98075111 |
131 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.97392856 |
132 | STAT3_23295773_ChIP-Seq_U87_Human | 0.94878332 |
133 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.94466740 |
134 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.93316952 |
135 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.92958439 |
136 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.92547344 |
137 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.90899699 |
138 | MYC_22102868_ChIP-Seq_BL_Human | 0.90586104 |
139 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.89891783 |
140 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.89432661 |
141 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.88701863 |
142 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.88546744 |
143 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.87480577 |
144 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.86188246 |
145 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.85370896 |
146 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.84102262 |
147 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.83672417 |
148 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.82018690 |
149 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.81967486 |
150 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.79830628 |
151 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.78418631 |
152 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.76837173 |
153 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.75949320 |
154 | * STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.75810889 |
155 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.75613904 |
156 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.75042633 |
157 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.74727061 |
158 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73944684 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.03018628 |
2 | MP0010094_abnormal_chromosome_stability | 4.17746574 |
3 | MP0004957_abnormal_blastocyst_morpholog | 4.08580753 |
4 | MP0008058_abnormal_DNA_repair | 3.99281143 |
5 | MP0003111_abnormal_nucleus_morphology | 3.59828376 |
6 | MP0002102_abnormal_ear_morphology | 3.47713558 |
7 | MP0003077_abnormal_cell_cycle | 3.39793801 |
8 | MP0003123_paternal_imprinting | 3.09846607 |
9 | MP0003806_abnormal_nucleotide_metabolis | 3.01761854 |
10 | MP0008057_abnormal_DNA_replication | 2.97283386 |
11 | MP0008007_abnormal_cellular_replicative | 2.92001895 |
12 | MP0009697_abnormal_copulation | 2.57479919 |
13 | MP0008932_abnormal_embryonic_tissue | 2.44083034 |
14 | MP0001529_abnormal_vocalization | 2.35031188 |
15 | MP0003122_maternal_imprinting | 2.30828477 |
16 | MP0000372_irregular_coat_pigmentation | 2.21406433 |
17 | MP0003786_premature_aging | 2.21267984 |
18 | MP0001984_abnormal_olfaction | 2.14772536 |
19 | MP0008789_abnormal_olfactory_epithelium | 2.11119759 |
20 | MP0005075_abnormal_melanosome_morpholog | 2.09689015 |
21 | MP0003718_maternal_effect | 2.06043947 |
22 | MP0002396_abnormal_hematopoietic_system | 2.05093648 |
23 | MP0003763_abnormal_thymus_physiology | 1.93942142 |
24 | MP0001764_abnormal_homeostasis | 1.90438751 |
25 | MP0000490_abnormal_crypts_of | 1.89051815 |
26 | MP0003787_abnormal_imprinting | 1.85697084 |
27 | MP0006036_abnormal_mitochondrial_physio | 1.81049819 |
28 | MP0005367_renal/urinary_system_phenotyp | 1.74159185 |
29 | MP0000516_abnormal_urinary_system | 1.74159185 |
30 | MP0001730_embryonic_growth_arrest | 1.67871711 |
31 | MP0005499_abnormal_olfactory_system | 1.67614792 |
32 | MP0005394_taste/olfaction_phenotype | 1.67614792 |
33 | MP0001348_abnormal_lacrimal_gland | 1.66476472 |
34 | MP0005253_abnormal_eye_physiology | 1.65609078 |
35 | MP0003937_abnormal_limbs/digits/tail_de | 1.61562495 |
36 | MP0006292_abnormal_olfactory_placode | 1.61023441 |
37 | MP0003567_abnormal_fetal_cardiomyocyte | 1.59578224 |
38 | MP0002233_abnormal_nose_morphology | 1.58436201 |
39 | MP0005408_hypopigmentation | 1.58409083 |
40 | MP0000569_abnormal_digit_pigmentation | 1.57804587 |
41 | MP0004147_increased_porphyrin_level | 1.55473567 |
42 | MP0003186_abnormal_redox_activity | 1.53356375 |
43 | MP0002876_abnormal_thyroid_physiology | 1.52039520 |
44 | MP0003136_yellow_coat_color | 1.50223974 |
45 | MP0005551_abnormal_eye_electrophysiolog | 1.43534147 |
46 | MP0005084_abnormal_gallbladder_morpholo | 1.40582637 |
47 | MP0002736_abnormal_nociception_after | 1.39674837 |
48 | MP0003195_calcinosis | 1.39613566 |
49 | MP0002163_abnormal_gland_morphology | 1.39311048 |
50 | MP0000350_abnormal_cell_proliferation | 1.37914468 |
51 | MP0006276_abnormal_autonomic_nervous | 1.36668493 |
52 | MP0002877_abnormal_melanocyte_morpholog | 1.34531721 |
53 | MP0008877_abnormal_DNA_methylation | 1.32319879 |
54 | MP0000313_abnormal_cell_death | 1.27438131 |
55 | MP0003011_delayed_dark_adaptation | 1.25999219 |
56 | MP0002080_prenatal_lethality | 1.24998868 |
57 | MP0003941_abnormal_skin_development | 1.24820831 |
58 | MP0002090_abnormal_vision | 1.24450012 |
59 | MP0006054_spinal_hemorrhage | 1.23700955 |
60 | MP0001697_abnormal_embryo_size | 1.23434040 |
61 | MP0009333_abnormal_splenocyte_physiolog | 1.21805280 |
62 | MP0002938_white_spotting | 1.20399614 |
63 | MP0002638_abnormal_pupillary_reflex | 1.17448663 |
64 | MP0000049_abnormal_middle_ear | 1.17075828 |
65 | MP0002234_abnormal_pharynx_morphology | 1.16786982 |
66 | MP0002653_abnormal_ependyma_morphology | 1.15626521 |
67 | MP0002095_abnormal_skin_pigmentation | 1.15013187 |
68 | MP0002019_abnormal_tumor_incidence | 1.14298376 |
69 | MP0001286_abnormal_eye_development | 1.14227248 |
70 | MP0001293_anophthalmia | 1.13295434 |
71 | MP0002837_dystrophic_cardiac_calcinosis | 1.12589374 |
72 | MP0003755_abnormal_palate_morphology | 1.12429342 |
73 | MP0010030_abnormal_orbit_morphology | 1.10598280 |
74 | MP0004264_abnormal_extraembryonic_tissu | 1.09625880 |
75 | MP0003121_genomic_imprinting | 1.09349462 |
76 | MP0004215_abnormal_myocardial_fiber | 1.09167893 |
77 | MP0003315_abnormal_perineum_morphology | 1.07580657 |
78 | MP0006035_abnormal_mitochondrial_morpho | 1.05645668 |
79 | MP0001672_abnormal_embryogenesis/_devel | 1.05227629 |
80 | MP0005380_embryogenesis_phenotype | 1.05227629 |
81 | MP0003880_abnormal_central_pattern | 1.04695373 |
82 | MP0005220_abnormal_exocrine_pancreas | 1.04100825 |
83 | MP0003890_abnormal_embryonic-extraembry | 1.02940317 |
84 | MP0000647_abnormal_sebaceous_gland | 1.02782242 |
85 | MP0005389_reproductive_system_phenotype | 1.02107035 |
86 | MP0001986_abnormal_taste_sensitivity | 1.00644192 |
87 | MP0000631_abnormal_neuroendocrine_gland | 1.00603773 |
88 | MP0004142_abnormal_muscle_tone | 1.00158778 |
89 | MP0005391_vision/eye_phenotype | 0.99971795 |
90 | MP0002132_abnormal_respiratory_system | 0.99231741 |
91 | MP0005379_endocrine/exocrine_gland_phen | 0.99206206 |
92 | MP0005171_absent_coat_pigmentation | 0.98924577 |
93 | MP0001299_abnormal_eye_distance/ | 0.98067710 |
94 | MP0001919_abnormal_reproductive_system | 0.97461750 |
95 | MP0000427_abnormal_hair_cycle | 0.96830802 |
96 | MP0004133_heterotaxia | 0.96767111 |
97 | MP0005187_abnormal_penis_morphology | 0.96265087 |
98 | MP0000778_abnormal_nervous_system | 0.95021909 |
99 | MP0001324_abnormal_eye_pigmentation | 0.94783462 |
100 | MP0008995_early_reproductive_senescence | 0.94681252 |
101 | MP0003984_embryonic_growth_retardation | 0.94679162 |
102 | MP0000358_abnormal_cell_content/ | 0.94400797 |
103 | MP0003183_abnormal_peptide_metabolism | 0.93806746 |
104 | MP0002282_abnormal_trachea_morphology | 0.92262976 |
105 | MP0000678_abnormal_parathyroid_gland | 0.90733157 |
106 | MP0002210_abnormal_sex_determination | 0.90378030 |
107 | MP0002088_abnormal_embryonic_growth/wei | 0.89673237 |
108 | MP0000371_diluted_coat_color | 0.89428533 |
109 | MP0010352_gastrointestinal_tract_polyps | 0.89161238 |
110 | MP0002160_abnormal_reproductive_system | 0.88166288 |
111 | MP0001186_pigmentation_phenotype | 0.88143244 |
112 | MP0002085_abnormal_embryonic_tissue | 0.87907466 |
113 | MP0005266_abnormal_metabolism | 0.85999245 |
114 | MP0001177_atelectasis | 0.85001856 |
115 | MP0001485_abnormal_pinna_reflex | 0.84962298 |
116 | MP0001145_abnormal_male_reproductive | 0.83792167 |
117 | MP0003119_abnormal_digestive_system | 0.83572154 |
118 | MP0002751_abnormal_autonomic_nervous | 0.82938840 |
119 | MP0003646_muscle_fatigue | 0.81689397 |
120 | MP0000689_abnormal_spleen_morphology | 0.81572139 |
121 | MP0001119_abnormal_female_reproductive | 0.80719870 |
122 | MP0000703_abnormal_thymus_morphology | 0.80706082 |
123 | MP0000015_abnormal_ear_pigmentation | 0.80633015 |
124 | MP0000681_abnormal_thyroid_gland | 0.80564738 |
125 | MP0005195_abnormal_posterior_eye | 0.80481963 |
126 | MP0001873_stomach_inflammation | 0.80286821 |
127 | MP0003385_abnormal_body_wall | 0.77990731 |
128 | MP0002722_abnormal_immune_system | 0.76354462 |
129 | MP0000013_abnormal_adipose_tissue | 0.76313557 |
130 | MP0002075_abnormal_coat/hair_pigmentati | 0.75515018 |
131 | MP0001929_abnormal_gametogenesis | 0.75515018 |
132 | MP0002752_abnormal_somatic_nervous | 0.74643359 |
133 | MP0005645_abnormal_hypothalamus_physiol | 0.74050236 |
134 | MP0006072_abnormal_retinal_apoptosis | 0.72939173 |
135 | MP0002084_abnormal_developmental_patter | 0.71801533 |
136 | MP0003866_abnormal_defecation | 0.71609171 |
137 | MP0002557_abnormal_social/conspecific_i | 0.70718839 |
138 | MP0000653_abnormal_sex_gland | 0.70687710 |
139 | MP0004043_abnormal_pH_regulation | 0.70575181 |
140 | MP0003935_abnormal_craniofacial_develop | 0.70197267 |
141 | MP0001853_heart_inflammation | 0.69892446 |
142 | MP0002086_abnormal_extraembryonic_tissu | 0.69536809 |
143 | MP0004808_abnormal_hematopoietic_stem | 0.69105710 |
144 | MP0004782_abnormal_surfactant_physiolog | 0.68744123 |
145 | MP0002398_abnormal_bone_marrow | 0.68437921 |
146 | MP0001188_hyperpigmentation | 0.67507971 |
147 | MP0004197_abnormal_fetal_growth/weight/ | 0.67311365 |
148 | MP0003943_abnormal_hepatobiliary_system | 0.66623331 |
149 | MP0003221_abnormal_cardiomyocyte_apopto | 0.66250031 |
150 | MP0005671_abnormal_response_to | 0.65504267 |
151 | MP0005397_hematopoietic_system_phenotyp | 0.63278559 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Aplastic anemia (HP:0001915) | 4.00113851 |
2 | Birth length less than 3rd percentile (HP:0003561) | 3.98923778 |
3 | Selective tooth agenesis (HP:0001592) | 3.90007020 |
4 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.69628309 |
5 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.69628309 |
6 | Type I transferrin isoform profile (HP:0003642) | 3.51621324 |
7 | Abnormality of the labia minora (HP:0012880) | 3.45371304 |
8 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.39531161 |
9 | Reticulocytopenia (HP:0001896) | 3.28281567 |
10 | Microvesicular hepatic steatosis (HP:0001414) | 3.27661802 |
11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.26817348 |
12 | Abnormal number of erythroid precursors (HP:0012131) | 3.24817696 |
13 | Hepatic necrosis (HP:0002605) | 3.21639612 |
14 | Generalized aminoaciduria (HP:0002909) | 3.14893154 |
15 | Acute necrotizing encephalopathy (HP:0006965) | 3.12421057 |
16 | Oral leukoplakia (HP:0002745) | 3.07330272 |
17 | Abnormality of the anterior horn cell (HP:0006802) | 2.96324936 |
18 | Degeneration of anterior horn cells (HP:0002398) | 2.96324936 |
19 | Rough bone trabeculation (HP:0100670) | 2.89019801 |
20 | Methylmalonic acidemia (HP:0002912) | 2.81127639 |
21 | Mitochondrial inheritance (HP:0001427) | 2.80904300 |
22 | * Increased serum lactate (HP:0002151) | 2.78789552 |
23 | Hepatocellular necrosis (HP:0001404) | 2.78213726 |
24 | Hyperglycinemia (HP:0002154) | 2.76002559 |
25 | Medial flaring of the eyebrow (HP:0010747) | 2.73385134 |
26 | * Increased CSF lactate (HP:0002490) | 2.71264302 |
27 | 11 pairs of ribs (HP:0000878) | 2.67380779 |
28 | Acute encephalopathy (HP:0006846) | 2.65883737 |
29 | Microretrognathia (HP:0000308) | 2.63346357 |
30 | Hypoplastic pelvis (HP:0008839) | 2.61973911 |
31 | Carpal bone hypoplasia (HP:0001498) | 2.59374099 |
32 | Abnormal protein glycosylation (HP:0012346) | 2.57828564 |
33 | Abnormal glycosylation (HP:0012345) | 2.57828564 |
34 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.57828564 |
35 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.57828564 |
36 | Abnormality of midbrain morphology (HP:0002418) | 2.57134345 |
37 | Molar tooth sign on MRI (HP:0002419) | 2.57134345 |
38 | Meckel diverticulum (HP:0002245) | 2.55056398 |
39 | Congenital primary aphakia (HP:0007707) | 2.53703378 |
40 | Gait imbalance (HP:0002141) | 2.45804827 |
41 | Abnormality of the ileum (HP:0001549) | 2.43359683 |
42 | Type 2 muscle fiber atrophy (HP:0003554) | 2.43118037 |
43 | Premature graying of hair (HP:0002216) | 2.41815166 |
44 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.41116005 |
45 | Lactic acidosis (HP:0003128) | 2.40128655 |
46 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.39952256 |
47 | Colon cancer (HP:0003003) | 2.38537016 |
48 | Genital tract atresia (HP:0001827) | 2.37929237 |
49 | Intestinal atresia (HP:0011100) | 2.37012308 |
50 | Nephrogenic diabetes insipidus (HP:0009806) | 2.36732610 |
51 | Macrocytic anemia (HP:0001972) | 2.35654323 |
52 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.34761843 |
53 | Irregular epiphyses (HP:0010582) | 2.34704738 |
54 | Hypoglycemic coma (HP:0001325) | 2.33921078 |
55 | Exercise intolerance (HP:0003546) | 2.33828255 |
56 | Lipid accumulation in hepatocytes (HP:0006561) | 2.33713737 |
57 | Neoplasm of the adrenal cortex (HP:0100641) | 2.31493818 |
58 | Breast hypoplasia (HP:0003187) | 2.30538676 |
59 | Renal cortical cysts (HP:0000803) | 2.30512783 |
60 | Bifid tongue (HP:0010297) | 2.29401354 |
61 | Vaginal atresia (HP:0000148) | 2.29147472 |
62 | Gonadotropin excess (HP:0000837) | 2.28763285 |
63 | Reduced antithrombin III activity (HP:0001976) | 2.27797325 |
64 | Progressive macrocephaly (HP:0004481) | 2.27469607 |
65 | Chromsome breakage (HP:0040012) | 2.25476313 |
66 | Abnormality of glycolysis (HP:0004366) | 2.25343028 |
67 | Increased serum pyruvate (HP:0003542) | 2.25343028 |
68 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.24884226 |
69 | Nephronophthisis (HP:0000090) | 2.24580805 |
70 | Abnormality of methionine metabolism (HP:0010901) | 2.24015736 |
71 | Patellar aplasia (HP:0006443) | 2.21609452 |
72 | Pallor (HP:0000980) | 2.17972168 |
73 | Medulloblastoma (HP:0002885) | 2.17526682 |
74 | Abnormal trabecular bone morphology (HP:0100671) | 2.15739517 |
75 | Septo-optic dysplasia (HP:0100842) | 2.15431573 |
76 | Abnormal spermatogenesis (HP:0008669) | 2.15299217 |
77 | Increased hepatocellular lipid droplets (HP:0006565) | 2.15006697 |
78 | Renal Fanconi syndrome (HP:0001994) | 2.14694812 |
79 | Thrombocytosis (HP:0001894) | 2.14202491 |
80 | Neoplasm of the adrenal gland (HP:0100631) | 2.11812545 |
81 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.10666568 |
82 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.09697535 |
83 | Dicarboxylic aciduria (HP:0003215) | 2.09697535 |
84 | Cellular immunodeficiency (HP:0005374) | 2.09066458 |
85 | Pancreatic fibrosis (HP:0100732) | 2.08639161 |
86 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.08525142 |
87 | Muscle fiber atrophy (HP:0100295) | 2.07614571 |
88 | Abnormality of chromosome stability (HP:0003220) | 2.05735650 |
89 | IgM deficiency (HP:0002850) | 2.05729339 |
90 | Increased intramyocellular lipid droplets (HP:0012240) | 2.05111726 |
91 | Poikiloderma (HP:0001029) | 2.04490533 |
92 | Increased muscle lipid content (HP:0009058) | 2.03794085 |
93 | Short tibia (HP:0005736) | 2.03049544 |
94 | Nausea (HP:0002018) | 2.02669772 |
95 | Adrenal hypoplasia (HP:0000835) | 2.01954910 |
96 | Abnormal lung lobation (HP:0002101) | 2.01610227 |
97 | Methylmalonic aciduria (HP:0012120) | 2.01186672 |
98 | Abnormality of serum amino acid levels (HP:0003112) | 2.01049919 |
99 | Proximal tubulopathy (HP:0000114) | 2.00641056 |
100 | Facial cleft (HP:0002006) | 2.00372321 |
101 | Cerebral edema (HP:0002181) | 1.99611980 |
102 | Pancytopenia (HP:0001876) | 1.98433086 |
103 | Hypothermia (HP:0002045) | 1.97592102 |
104 | Ependymoma (HP:0002888) | 1.96533100 |
105 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.95548173 |
106 | Glycosuria (HP:0003076) | 1.95491055 |
107 | Abnormality of urine glucose concentration (HP:0011016) | 1.95491055 |
108 | Abnormality of the renal cortex (HP:0011035) | 1.93903260 |
109 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92945691 |
110 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.92641583 |
111 | 3-Methylglutaconic aciduria (HP:0003535) | 1.92056977 |
112 | Pancreatic cysts (HP:0001737) | 1.91982046 |
113 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.90279246 |
114 | Ragged-red muscle fibers (HP:0003200) | 1.89835313 |
115 | True hermaphroditism (HP:0010459) | 1.89194714 |
116 | Abnormal hair whorl (HP:0010721) | 1.88321069 |
117 | Optic nerve coloboma (HP:0000588) | 1.88122869 |
118 | Supernumerary spleens (HP:0009799) | 1.87080692 |
119 | Rhabdomyosarcoma (HP:0002859) | 1.85229591 |
120 | Lymphoma (HP:0002665) | 1.85198697 |
121 | Bone marrow hypocellularity (HP:0005528) | 1.84633240 |
122 | Poor coordination (HP:0002370) | 1.84457796 |
123 | Respiratory failure (HP:0002878) | 1.84318400 |
124 | Prominent metopic ridge (HP:0005487) | 1.84071870 |
125 | Abnormality of vitamin B metabolism (HP:0004340) | 1.83846417 |
126 | Glioma (HP:0009733) | 1.83421534 |
127 | Megaloblastic anemia (HP:0001889) | 1.83052710 |
128 | Abnormality of the metopic suture (HP:0005556) | 1.82429514 |
129 | Trismus (HP:0000211) | 1.82427845 |
130 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.81767780 |
131 | Cortical dysplasia (HP:0002539) | 1.80709734 |
132 | Optic disc pallor (HP:0000543) | 1.80351587 |
133 | Abolished electroretinogram (ERG) (HP:0000550) | 1.80170216 |
134 | Hepatoblastoma (HP:0002884) | 1.79961441 |
135 | Respiratory difficulties (HP:0002880) | 1.79703112 |
136 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.79680181 |
137 | Abnormality of alanine metabolism (HP:0010916) | 1.79550896 |
138 | Hyperalaninemia (HP:0003348) | 1.79550896 |
139 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.79550896 |
140 | Abnormality of the preputium (HP:0100587) | 1.79423348 |
141 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.78918993 |
142 | Hypoplasia of the radius (HP:0002984) | 1.78704424 |
143 | Astigmatism (HP:0000483) | 1.78637211 |
144 | Sloping forehead (HP:0000340) | 1.78401206 |
145 | Myelodysplasia (HP:0002863) | 1.78186522 |
146 | Abnormal biliary tract physiology (HP:0012439) | 1.77904172 |
147 | Bile duct proliferation (HP:0001408) | 1.77904172 |
148 | Abnormality of glycine metabolism (HP:0010895) | 1.77321498 |
149 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.77321498 |
150 | Abnormality of the renal medulla (HP:0100957) | 1.77226705 |
151 | Absent thumb (HP:0009777) | 1.76402880 |
152 | Optic nerve hypoplasia (HP:0000609) | 1.76205700 |
153 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.76106132 |
154 | Tubulointerstitial nephritis (HP:0001970) | 1.76006909 |
155 | Postaxial hand polydactyly (HP:0001162) | 1.75904745 |
156 | Sclerocornea (HP:0000647) | 1.71938768 |
157 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.70825940 |
158 | Lethargy (HP:0001254) | 1.69520579 |
159 | Small intestinal stenosis (HP:0012848) | 1.68592765 |
160 | Duodenal stenosis (HP:0100867) | 1.68592765 |
161 | Stenosis of the external auditory canal (HP:0000402) | 1.67029547 |
162 | Volvulus (HP:0002580) | 1.65764144 |
163 | Dandy-Walker malformation (HP:0001305) | 1.65499785 |
164 | Abnormality of the duodenum (HP:0002246) | 1.64737132 |
165 | Decreased testicular size (HP:0008734) | 1.63948026 |
166 | Abnormality of the astrocytes (HP:0100707) | 1.62228188 |
167 | Astrocytoma (HP:0009592) | 1.62228188 |
168 | Postaxial foot polydactyly (HP:0001830) | 1.61200441 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EIF2AK1 | 4.58042338 |
2 | WEE1 | 3.85946338 |
3 | BUB1 | 3.61671675 |
4 | EIF2AK3 | 3.54835582 |
5 | TRIM28 | 3.34010931 |
6 | STK16 | 3.16836585 |
7 | PASK | 2.86491877 |
8 | FRK | 2.78489811 |
9 | MAP4K2 | 2.77678167 |
10 | CDC7 | 2.76531484 |
11 | NEK1 | 2.69090353 |
12 | SRPK1 | 2.63289051 |
13 | BRSK2 | 2.61935359 |
14 | BCR | 2.40023049 |
15 | TSSK6 | 2.24662456 |
16 | NME2 | 2.17655481 |
17 | ACVR1B | 2.09847116 |
18 | FLT3 | 2.05719227 |
19 | MST4 | 1.98397028 |
20 | VRK1 | 1.88863675 |
21 | MKNK1 | 1.84556453 |
22 | BCKDK | 1.79284249 |
23 | BRSK1 | 1.77366071 |
24 | ZAK | 1.70515885 |
25 | PLK2 | 1.65780191 |
26 | NEK2 | 1.63268196 |
27 | PLK4 | 1.58858968 |
28 | MKNK2 | 1.53029507 |
29 | SCYL2 | 1.52297840 |
30 | MAP3K4 | 1.49567860 |
31 | TGFBR1 | 1.48563402 |
32 | ATR | 1.47476816 |
33 | TTK | 1.40396580 |
34 | CASK | 1.39070086 |
35 | PLK1 | 1.38869651 |
36 | CDK7 | 1.35275152 |
37 | PLK3 | 1.28879098 |
38 | AURKB | 1.27174341 |
39 | GRK1 | 1.26970662 |
40 | DYRK3 | 1.24735331 |
41 | RPS6KB2 | 1.24442181 |
42 | CSNK1G1 | 1.21517022 |
43 | MAPK13 | 1.17450107 |
44 | CSNK1G3 | 1.12093355 |
45 | CDK8 | 1.11376783 |
46 | EIF2AK2 | 1.10232610 |
47 | PAK3 | 1.08851985 |
48 | CSNK1G2 | 1.08342885 |
49 | MAPKAPK3 | 1.08234396 |
50 | RPS6KA4 | 1.07208529 |
51 | MAP3K12 | 1.01244235 |
52 | INSRR | 1.00049876 |
53 | AURKA | 0.98882188 |
54 | PDK4 | 0.97520103 |
55 | PDK3 | 0.97520103 |
56 | ERBB3 | 0.95693525 |
57 | CCNB1 | 0.94519695 |
58 | STK10 | 0.94397911 |
59 | PNCK | 0.91980813 |
60 | CSNK1A1L | 0.91111076 |
61 | EPHA2 | 0.90865729 |
62 | FGFR2 | 0.89318437 |
63 | ADRBK2 | 0.89314551 |
64 | VRK2 | 0.89223516 |
65 | AKT3 | 0.87066502 |
66 | STK39 | 0.84530085 |
67 | TIE1 | 0.82999516 |
68 | PINK1 | 0.82227687 |
69 | TLK1 | 0.82160691 |
70 | NUAK1 | 0.81621376 |
71 | STK3 | 0.81509410 |
72 | MAP3K3 | 0.81357121 |
73 | TAF1 | 0.80232535 |
74 | NME1 | 0.78886821 |
75 | PRKCE | 0.77620014 |
76 | MINK1 | 0.76498399 |
77 | MUSK | 0.73884865 |
78 | TEC | 0.73706889 |
79 | TAOK2 | 0.73661324 |
80 | MAP3K8 | 0.72688043 |
81 | CSNK2A1 | 0.72658501 |
82 | LATS1 | 0.72343818 |
83 | MARK1 | 0.71200255 |
84 | TNIK | 0.69651150 |
85 | CHEK2 | 0.68185256 |
86 | PAK4 | 0.67545448 |
87 | YES1 | 0.67517845 |
88 | PIM2 | 0.67235896 |
89 | MAP4K1 | 0.67166865 |
90 | PRKCG | 0.66775754 |
91 | BRAF | 0.66275964 |
92 | CHEK1 | 0.64519754 |
93 | IRAK4 | 0.60908985 |
94 | OXSR1 | 0.59997927 |
95 | CSNK2A2 | 0.59780666 |
96 | ATM | 0.58918753 |
97 | PIM1 | 0.58597302 |
98 | WNK4 | 0.58575921 |
99 | SIK3 | 0.58491913 |
100 | KDR | 0.57875654 |
101 | CDK4 | 0.56658273 |
102 | BTK | 0.56377616 |
103 | PRKCI | 0.55907026 |
104 | BMPR1B | 0.55311149 |
105 | TESK1 | 0.54948992 |
106 | CAMKK2 | 0.53999023 |
107 | KIT | 0.53546083 |
108 | WNK3 | 0.52519129 |
109 | CDK19 | 0.51364455 |
110 | TESK2 | 0.49371111 |
111 | TXK | 0.48531703 |
112 | DAPK1 | 0.47870823 |
113 | CDK2 | 0.47366220 |
114 | PBK | 0.47088819 |
115 | RPS6KB1 | 0.45151470 |
116 | ADRBK1 | 0.45136996 |
117 | PDK2 | 0.45098195 |
118 | OBSCN | 0.44350140 |
119 | STK38L | 0.43961665 |
120 | FGFR1 | 0.43428152 |
121 | DYRK1B | 0.42392733 |
122 | CSNK1E | 0.41844960 |
123 | IRAK3 | 0.41539363 |
124 | PIK3CA | 0.41459669 |
125 | MAP3K11 | 0.40953501 |
126 | MAP2K6 | 0.40102050 |
127 | MYLK | 0.39825900 |
128 | EPHB2 | 0.39361621 |
129 | MAP2K7 | 0.37919423 |
130 | EPHA4 | 0.37703249 |
131 | RPS6KA5 | 0.36805474 |
132 | RPS6KC1 | 0.35120581 |
133 | RPS6KL1 | 0.35120581 |
134 | CSNK1A1 | 0.34227262 |
135 | STK4 | 0.33187042 |
136 | MARK3 | 0.32876787 |
137 | DYRK2 | 0.32844345 |
138 | NEK6 | 0.32446791 |
139 | ERBB4 | 0.32318986 |
140 | CSF1R | 0.32222475 |
141 | RPS6KA6 | 0.32027042 |
142 | BRD4 | 0.31822864 |
143 | CSNK1D | 0.30632175 |
144 | FER | 0.29119311 |
145 | PRKDC | 0.28918298 |
146 | MAPKAPK5 | 0.28886746 |
147 | PRKACB | 0.28835843 |
148 | CDK1 | 0.28269287 |
149 | CDK3 | 0.27126884 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.52077296 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.19614161 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.86436136 |
4 | Ribosome_Homo sapiens_hsa03010 | 3.47055123 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.10583586 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.05081276 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.98545765 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.81241168 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.76481488 |
10 | * Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.67724554 |
11 | Base excision repair_Homo sapiens_hsa03410 | 2.62631307 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.56017222 |
13 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.55351370 |
14 | RNA transport_Homo sapiens_hsa03013 | 2.53100428 |
15 | Protein export_Homo sapiens_hsa03060 | 2.49102399 |
16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.15189703 |
17 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.07575126 |
18 | Cell cycle_Homo sapiens_hsa04110 | 2.07013300 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 2.01777690 |
20 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.00976286 |
21 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.98408979 |
22 | RNA degradation_Homo sapiens_hsa03018 | 1.81911517 |
23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.73521160 |
24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.69416255 |
25 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.61562801 |
26 | Purine metabolism_Homo sapiens_hsa00230 | 1.56119605 |
27 | Parkinsons disease_Homo sapiens_hsa05012 | 1.50669627 |
28 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.41034509 |
29 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.34838639 |
30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.33193394 |
31 | Phototransduction_Homo sapiens_hsa04744 | 1.30158314 |
32 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.30049425 |
33 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.22121541 |
34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.20332619 |
35 | Huntingtons disease_Homo sapiens_hsa05016 | 1.16618798 |
36 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.08954816 |
37 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.07842807 |
38 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.03447960 |
39 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.03062235 |
40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.02952353 |
41 | Carbon metabolism_Homo sapiens_hsa01200 | 0.99614521 |
42 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.98439553 |
43 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.95857221 |
44 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.95112235 |
45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94572502 |
46 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.92414314 |
47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.91812075 |
48 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.91222387 |
49 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.90008643 |
50 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.89682840 |
51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.86718354 |
52 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.85239982 |
53 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.84891411 |
54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.84530484 |
55 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.83912661 |
56 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.80711915 |
57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.80162520 |
58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.80067570 |
59 | Galactose metabolism_Homo sapiens_hsa00052 | 0.79834663 |
60 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.77956510 |
61 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.77890100 |
62 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.77598431 |
63 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.75336883 |
64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.74430578 |
65 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.74303453 |
66 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.73556560 |
67 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72075566 |
68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71848154 |
69 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.70955598 |
70 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69129995 |
71 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.69067836 |
72 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.66883682 |
73 | Alzheimers disease_Homo sapiens_hsa05010 | 0.65959772 |
74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64592180 |
75 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.63768113 |
76 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62902216 |
77 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.61776122 |
78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.61694117 |
79 | Circadian rhythm_Homo sapiens_hsa04710 | 0.61476670 |
80 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.61279672 |
81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.60931656 |
82 | Legionellosis_Homo sapiens_hsa05134 | 0.60631885 |
83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.60313846 |
84 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59062900 |
85 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.58433353 |
86 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.56314976 |
87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.56026878 |
88 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.55877368 |
89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55629514 |
90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.54547814 |
91 | Thyroid cancer_Homo sapiens_hsa05216 | 0.51685262 |
92 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.46402309 |
93 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.46328388 |
94 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.46072394 |
95 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.45153688 |
96 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44247821 |
97 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.44142756 |
98 | Peroxisome_Homo sapiens_hsa04146 | 0.43134945 |
99 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42737348 |
100 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.41025629 |
101 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.40993634 |
102 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40716592 |
103 | Other glycan degradation_Homo sapiens_hsa00511 | 0.40177271 |
104 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39100232 |
105 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.38677909 |
106 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.37737479 |
107 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36586876 |
108 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.36150672 |
109 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.35051015 |
110 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.34111740 |
111 | Olfactory transduction_Homo sapiens_hsa04740 | 0.33681438 |
112 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.32570220 |
113 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.24905597 |
114 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.24870597 |
115 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.24044943 |
116 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.23186747 |
117 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.20824930 |
118 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.20579623 |
119 | HTLV-I infection_Homo sapiens_hsa05166 | 0.19922553 |
120 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.19873765 |
121 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.19721779 |
122 | Alcoholism_Homo sapiens_hsa05034 | 0.19296574 |
123 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.13843128 |
124 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.13004233 |
125 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.12050914 |
126 | Apoptosis_Homo sapiens_hsa04210 | 0.08938521 |
127 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.08697834 |
128 | Measles_Homo sapiens_hsa05162 | 0.07396439 |
129 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.06099089 |
130 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.05601937 |
131 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.05425598 |
132 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.04488203 |
133 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.04085935 |
134 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.02570844 |