RASD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of synapse structural plasticity (GO:0051823)6.10396423
2prepulse inhibition (GO:0060134)5.97989120
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.88599533
4locomotory exploration behavior (GO:0035641)5.44908229
5striatum development (GO:0021756)5.29404343
6cellular potassium ion homeostasis (GO:0030007)5.28613453
7regulation of short-term neuronal synaptic plasticity (GO:0048172)5.28498999
8sodium ion export (GO:0071436)5.22147645
9synaptic vesicle maturation (GO:0016188)5.21213299
10adenosine receptor signaling pathway (GO:0001973)5.10300034
11vocalization behavior (GO:0071625)5.02591676
12auditory behavior (GO:0031223)5.01295983
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.00751325
14adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)5.00697759
15regulation of long-term neuronal synaptic plasticity (GO:0048169)5.00239257
16membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.91977106
17regulation of glutamate receptor signaling pathway (GO:1900449)4.80257703
18* synaptic transmission, dopaminergic (GO:0001963)4.78254460
19positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.75070807
20response to amphetamine (GO:0001975)4.72394596
21regulation of neuronal synaptic plasticity (GO:0048168)4.64745924
22neurotransmitter-gated ion channel clustering (GO:0072578)4.64380350
23positive regulation of synaptic transmission, glutamatergic (GO:0051968)4.60782647
24positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.54409439
25behavioral response to cocaine (GO:0048148)4.53718796
26cerebellar granule cell differentiation (GO:0021707)4.52895490
27negative regulation of cytosolic calcium ion concentration (GO:0051481)4.50031151
28positive regulation of synapse maturation (GO:0090129)4.42569363
29regulation of dendritic spine morphogenesis (GO:0061001)4.41318552
30dopamine receptor signaling pathway (GO:0007212)4.41250589
31dendritic spine organization (GO:0097061)4.39784526
32positive regulation of synaptic transmission, GABAergic (GO:0032230)4.39311011
33negative regulation of synaptic transmission, glutamatergic (GO:0051967)4.38669071
34regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.35664582
35regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)4.32980569
36regulation of dopamine uptake involved in synaptic transmission (GO:0051584)4.32980569
37response to auditory stimulus (GO:0010996)4.28632819
38positive regulation of neurotransmitter transport (GO:0051590)4.27630679
39neuronal action potential propagation (GO:0019227)4.26071921
40ionotropic glutamate receptor signaling pathway (GO:0035235)4.25924200
41cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.25792811
42positive regulation of dendritic spine development (GO:0060999)4.25240835
43synaptic vesicle exocytosis (GO:0016079)4.23599147
44cAMP catabolic process (GO:0006198)4.23031472
45cytoskeletal anchoring at plasma membrane (GO:0007016)4.21477822
46substrate-independent telencephalic tangential migration (GO:0021826)4.21036698
47substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.21036698
48dendritic spine morphogenesis (GO:0060997)4.18611660
49neuromuscular process controlling balance (GO:0050885)4.18416331
50synaptic vesicle docking involved in exocytosis (GO:0016081)4.15750515
51negative regulation of synaptic transmission, GABAergic (GO:0032229)4.12624343
52regulation of synaptic vesicle exocytosis (GO:2000300)4.10365377
53neurotransmitter transport (GO:0006836)4.02001500
54regulation of female receptivity (GO:0045924)4.01725035
55long-term memory (GO:0007616)3.99745213
56L-amino acid import (GO:0043092)3.99558439
57regulation of excitatory postsynaptic membrane potential (GO:0060079)3.99486838
58transmission of nerve impulse (GO:0019226)3.98137089
59protein localization to synapse (GO:0035418)3.97846183
60neurotransmitter secretion (GO:0007269)3.96602377
61regulation of synaptic transmission, glutamatergic (GO:0051966)3.95099762
62regulation of neurotransmitter uptake (GO:0051580)3.92354682
63regulation of glutamate secretion (GO:0014048)3.92017407
64* neuron-neuron synaptic transmission (GO:0007270)3.89326417
65positive regulation of membrane potential (GO:0045838)3.87765687
66G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.87699527
67synaptic transmission, glutamatergic (GO:0035249)3.85451562
68neuronal ion channel clustering (GO:0045161)3.82591861
69exploration behavior (GO:0035640)3.82464618
70peristalsis (GO:0030432)3.80925522
71amino acid import (GO:0043090)3.80331060
72regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.77296280
73cyclic nucleotide catabolic process (GO:0009214)3.75016541
74positive regulation of neurotransmitter secretion (GO:0001956)3.73776259
75cell communication by electrical coupling (GO:0010644)3.71578191
76potassium ion import (GO:0010107)3.69971506
77phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.69883994
78mechanosensory behavior (GO:0007638)3.69446702
79regulation of synaptic vesicle transport (GO:1902803)3.69047995
80regulation of postsynaptic membrane potential (GO:0060078)3.67565402
81chemosensory behavior (GO:0007635)3.65649217
82gamma-aminobutyric acid transport (GO:0015812)3.65340815
83regulation of synaptic plasticity (GO:0048167)3.63607415
84regulation of neurotransmitter secretion (GO:0046928)3.63431833
85regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.63216093
86glutamate receptor signaling pathway (GO:0007215)3.61309754
87regulation of ARF protein signal transduction (GO:0032012)3.61022868
88visual learning (GO:0008542)3.60880420
89layer formation in cerebral cortex (GO:0021819)3.55980629
90female mating behavior (GO:0060180)3.55839988
91negative regulation of dendrite morphogenesis (GO:0050774)3.54257419
92behavioral fear response (GO:0001662)3.53446046
93behavioral defense response (GO:0002209)3.53446046
94synaptic vesicle endocytosis (GO:0048488)3.53177281
95response to histamine (GO:0034776)3.50078049
96regulation of synapse maturation (GO:0090128)3.47977948
97cAMP metabolic process (GO:0046058)3.47150109
98membrane hyperpolarization (GO:0060081)3.46584679
99regulation of protein kinase A signaling (GO:0010738)3.46467549
100mating behavior (GO:0007617)3.44819421
101cell communication involved in cardiac conduction (GO:0086065)3.44793143
102regulation of neurotransmitter levels (GO:0001505)3.44677730
103glutamate secretion (GO:0014047)3.43576377
104positive regulation of dendritic spine morphogenesis (GO:0061003)3.42257268
105postsynaptic membrane organization (GO:0001941)3.42043429
106potassium ion homeostasis (GO:0055075)3.41747943
107regulation of dendritic spine development (GO:0060998)3.40951043
108long-term synaptic potentiation (GO:0060291)3.40839304
109glycine transport (GO:0015816)3.40675073
110regulation of voltage-gated calcium channel activity (GO:1901385)3.40201942
111negative regulation of dendrite development (GO:2000171)3.40193434
112visual behavior (GO:0007632)3.39412138
113activation of protein kinase A activity (GO:0034199)3.38001769
114regulation of cell communication by electrical coupling (GO:0010649)3.34562607
115neuromuscular synaptic transmission (GO:0007274)3.27694658
116regulation of synaptic transmission, GABAergic (GO:0032228)3.27656961
117neuron cell-cell adhesion (GO:0007158)3.27126007
118response to amine (GO:0014075)3.24218424
119cellular sodium ion homeostasis (GO:0006883)3.23483418
120drinking behavior (GO:0042756)3.22078486
121learning (GO:0007612)3.21468506
122membrane depolarization (GO:0051899)3.20371375
123regulation of synaptic transmission, dopaminergic (GO:0032225)3.18946598
124neuromuscular process controlling posture (GO:0050884)3.18607644
125negative regulation of amino acid transport (GO:0051956)3.18173637
126regulation of vesicle fusion (GO:0031338)3.17916240
127cerebellar Purkinje cell differentiation (GO:0021702)3.16843826
128regulation of neurotransmitter transport (GO:0051588)3.15738430
129positive regulation of synaptic transmission (GO:0050806)3.14902369
130neuromuscular process (GO:0050905)3.13995649
131fear response (GO:0042596)3.12823832
132membrane depolarization during action potential (GO:0086010)3.11975852
133regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.10307521
134cAMP biosynthetic process (GO:0006171)3.06630238
135positive regulation of dendrite development (GO:1900006)3.03372426
136gamma-aminobutyric acid signaling pathway (GO:0007214)3.01201968
137proline transport (GO:0015824)2.99913578
138intraspecies interaction between organisms (GO:0051703)2.94372242
139social behavior (GO:0035176)2.94372242
140regulation of synaptic transmission (GO:0050804)2.91677080
141* synaptic transmission (GO:0007268)2.91156419
142central nervous system myelination (GO:0022010)2.91033083
143axon ensheathment in central nervous system (GO:0032291)2.91033083
144cellular potassium ion transport (GO:0071804)2.84582329
145potassium ion transmembrane transport (GO:0071805)2.84582329
146cardiac conduction (GO:0061337)2.80021977
147righting reflex (GO:0060013)2.78008141
148acid secretion (GO:0046717)2.76026962

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.07914399
2* RARB_27405468_Chip-Seq_BRAIN_Mouse3.78567544
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.19059375
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.14155685
5GBX2_23144817_ChIP-Seq_PC3_Human3.07662806
6* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00812594
7THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.97077376
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82933906
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82933906
10DROSHA_22980978_ChIP-Seq_HELA_Human2.77313969
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.75233798
12* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.72774079
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.67223973
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.64541203
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.60674412
16REST_21632747_ChIP-Seq_MESCs_Mouse2.60410452
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.59834470
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.57192299
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.55258135
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.39063488
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.33054289
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.32013683
23EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.27014762
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.23720551
25IKZF1_21737484_ChIP-ChIP_HCT116_Human2.23390467
26REST_18959480_ChIP-ChIP_MESCs_Mouse2.16335017
27AR_21572438_ChIP-Seq_LNCaP_Human2.09457811
28EED_16625203_ChIP-ChIP_MESCs_Mouse2.07970643
29ESR2_21235772_ChIP-Seq_MCF-7_Human1.96328790
30PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.92820522
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.84147916
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.79280428
33LXR_22292898_ChIP-Seq_THP-1_Human1.73598497
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.73385929
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.63131233
36* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49445849
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48251473
38KDM2B_26808549_Chip-Seq_SUP-B15_Human1.46660313
39DNAJC2_21179169_ChIP-ChIP_NT2_Human1.45759916
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.43068694
41TAF15_26573619_Chip-Seq_HEK293_Human1.41557393
42SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.41361098
43SMAD4_21799915_ChIP-Seq_A2780_Human1.38163000
44PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.37078991
45GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36797298
46RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.36097310
47KDM2B_26808549_Chip-Seq_K562_Human1.32059024
48RING1B_27294783_Chip-Seq_ESCs_Mouse1.30800752
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30582684
50* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.30361439
51P53_22127205_ChIP-Seq_FIBROBLAST_Human1.29718808
52TRIM28_21343339_ChIP-Seq_HEK293_Human1.29369555
53TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.26455239
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.26160309
55WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22252973
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.22118709
57VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21248152
58* SOX2_21211035_ChIP-Seq_LN229_Gbm1.20858051
59AR_19668381_ChIP-Seq_PC3_Human1.18557709
60EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.18273871
61PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18235101
62RING1B_27294783_Chip-Seq_NPCs_Mouse1.17904743
63CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17423776
64STAT3_23295773_ChIP-Seq_U87_Human1.14734061
65CREB1_26743006_Chip-Seq_LNCaP_Human1.12299162
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12082831
67SMC4_20622854_ChIP-Seq_HELA_Human1.11916434
68SMAD3_21741376_ChIP-Seq_HESCs_Human1.11295051
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.10951333
70ZFP281_18757296_ChIP-ChIP_E14_Mouse1.10479191
71GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09881012
72SMAD_19615063_ChIP-ChIP_OVARY_Human1.04828388
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04431389
74P300_19829295_ChIP-Seq_ESCs_Human1.03858252
75SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03812342
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03592594
77EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02564743
78* CTCF_27219007_Chip-Seq_Bcells_Human1.02195099
79KDM2B_26808549_Chip-Seq_DND41_Human1.02023931
80OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.01851076
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.01170162
82PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99006200
83TCF4_23295773_ChIP-Seq_U87_Human0.98630660
84MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98409634
85ZFP57_27257070_Chip-Seq_ESCs_Mouse0.98238402
86UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.97945102
87ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.97938544
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.97878447
89AHR_22903824_ChIP-Seq_MCF-7_Human0.97789519
90* CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96889062
91CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96862183
92TP53_20018659_ChIP-ChIP_R1E_Mouse0.96617118
93ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95238777
94YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95075826
95BMI1_23680149_ChIP-Seq_NPCS_Mouse0.94949373
96AR_25329375_ChIP-Seq_VCAP_Human0.94324159
97RACK7_27058665_Chip-Seq_MCF-7_Human0.94073739
98CBX2_27304074_Chip-Seq_ESCs_Mouse0.93974037
99RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.93435696
100SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92299329
101SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91894879
102KLF4_19829295_ChIP-Seq_ESCs_Human0.91704839
103ESR1_20079471_ChIP-ChIP_T-47D_Human0.91251727
104RXR_22108803_ChIP-Seq_LS180_Human0.91162529
105SMAD4_21741376_ChIP-Seq_HESCs_Human0.90723482
106RUNX2_22187159_ChIP-Seq_PCA_Human0.90613071
107P68_20966046_ChIP-Seq_HELA_Human0.90600768
108EGR1_19032775_ChIP-ChIP_M12_Human0.90550511
109TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89783176
110OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.89404282
111ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89366848
112ARNT_22903824_ChIP-Seq_MCF-7_Human0.89317234
113CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.88889587
114SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.88812173
115TOP2B_26459242_ChIP-Seq_MCF-7_Human0.88741506
116NR3C1_21868756_ChIP-Seq_MCF10A_Human0.88242534
117GATA1_26923725_Chip-Seq_HPCs_Mouse0.88020487
118TET1_21490601_ChIP-Seq_MESCs_Mouse0.87731439
119SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86422072
120RNF2_27304074_Chip-Seq_NSC_Mouse0.85935971
121PIAS1_25552417_ChIP-Seq_VCAP_Human0.85147684
122* SMAD3_21741376_ChIP-Seq_ESCs_Human0.83721016
123DPY_21335234_ChIP-Seq_ESCs_Mouse0.83588915
124GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.83496274
125UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83404395
126PRDM14_20953172_ChIP-Seq_ESCs_Human0.83189659
127ESR1_21235772_ChIP-Seq_MCF-7_Human0.82959489
128* OCT4_19829295_ChIP-Seq_ESCs_Human0.81965752
129TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.80809055
130* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.80545529
131MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.79957216
132EP300_21415370_ChIP-Seq_HL-1_Mouse0.78775384
133SA1_27219007_Chip-Seq_Bcells_Human0.78653103
134SA1_27219007_Chip-Seq_ERYTHROID_Human0.78089303
135TET1_21451524_ChIP-Seq_MESCs_Mouse0.76576224
136CTNNB1_20460455_ChIP-Seq_HCT116_Human0.76414650
137* TP53_23651856_ChIP-Seq_MEFs_Mouse0.75998683
138MYC_27129775_Chip-Seq_CORNEA_Mouse0.75612798
139TP63_22573176_ChIP-Seq_HFKS_Human0.75176520
140ISL1_27105846_Chip-Seq_CPCs_Mouse0.74233561
141KDM2B_26808549_Chip-Seq_JURKAT_Human0.74140615
142NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.71950605

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy9.05277985
2MP0004859_abnormal_synaptic_plasticity6.32116470
3MP0003880_abnormal_central_pattern4.22470383
4MP0003635_abnormal_synaptic_transmissio4.05793487
5MP0009745_abnormal_behavioral_response3.71762087
6MP0002063_abnormal_learning/memory/cond3.40376885
7MP0004270_analgesia3.17143296
8MP0002064_seizures2.99139544
9MP0001486_abnormal_startle_reflex2.84680201
10MP0009046_muscle_twitch2.83586482
11MP0001529_abnormal_vocalization2.79353225
12* MP0002572_abnormal_emotion/affect_behav2.68131023
13MP0002272_abnormal_nervous_system2.51867245
14MP0005423_abnormal_somatic_nervous2.45894530
15MP0001968_abnormal_touch/_nociception2.42584617
16MP0002909_abnormal_adrenal_gland2.35161059
17MP0005646_abnormal_pituitary_gland2.16581567
18MP0001501_abnormal_sleep_pattern2.10873599
19MP0002734_abnormal_mechanical_nocicepti2.04406924
20MP0005386_behavior/neurological_phenoty1.93757450
21MP0004924_abnormal_behavior1.93757450
22MP0005409_darkened_coat_color1.92994094
23MP0001970_abnormal_pain_threshold1.74223680
24MP0008569_lethality_at_weaning1.72997340
25MP0004130_abnormal_muscle_cell1.69157342
26MP0002733_abnormal_thermal_nociception1.67642316
27MP0001188_hyperpigmentation1.67414473
28MP0002557_abnormal_social/conspecific_i1.66193214
29MP0000579_abnormal_nail_morphology1.62237320
30MP0004811_abnormal_neuron_physiology1.61732764
31MP0001984_abnormal_olfaction1.59851627
32MP0002736_abnormal_nociception_after1.59732910
33MP0001440_abnormal_grooming_behavior1.57585420
34MP0003879_abnormal_hair_cell1.52571259
35MP0002067_abnormal_sensory_capabilities1.50644658
36MP0009780_abnormal_chondrocyte_physiolo1.40950979
37MP0003075_altered_response_to1.37804127
38MP0005167_abnormal_blood-brain_barrier1.33330158
39MP0004885_abnormal_endolymph1.31666888
40MP0001905_abnormal_dopamine_level1.31157954
41MP0003633_abnormal_nervous_system1.29435267
42MP0008874_decreased_physiological_sensi1.28218548
43MP0001177_atelectasis1.26806901
44* MP0002066_abnormal_motor_capabilities/c1.26075698
45MP0002735_abnormal_chemical_nociception1.25903640
46MP0008872_abnormal_physiological_respon1.25303880
47MP0005623_abnormal_meninges_morphology1.24481955
48MP0002184_abnormal_innervation1.23609498
49MP0000955_abnormal_spinal_cord1.21959760
50MP0001346_abnormal_lacrimal_gland1.17624396
51MP0003329_amyloid_beta_deposits1.14944991
52MP0000013_abnormal_adipose_tissue1.14256219
53MP0002882_abnormal_neuron_morphology1.12851476
54MP0003283_abnormal_digestive_organ1.07841218
55MP0001348_abnormal_lacrimal_gland1.07354579
56MP0005451_abnormal_body_composition1.07120620
57MP0000778_abnormal_nervous_system1.04828315
58MP0008961_abnormal_basal_metabolism1.04073823
59MP0000749_muscle_degeneration1.03727596
60MP0003690_abnormal_glial_cell1.00525963
61MP0003631_nervous_system_phenotype1.00314041
62MP0004085_abnormal_heartbeat0.99905763
63MP0003123_paternal_imprinting0.99368454
64MP0001502_abnormal_circadian_rhythm0.98592033
65MP0005084_abnormal_gallbladder_morpholo0.96049505
66MP0010234_abnormal_vibrissa_follicle0.95939748
67MP0004858_abnormal_nervous_system0.95874252
68MP0004142_abnormal_muscle_tone0.94689837
69MP0000751_myopathy0.94390204
70MP0000747_muscle_weakness0.93709295
71MP0002069_abnormal_eating/drinking_beha0.92781466
72MP0003787_abnormal_imprinting0.92488857
73MP0004510_myositis0.90123925
74MP0000920_abnormal_myelination0.89758897
75MP0005535_abnormal_body_temperature0.88544802
76MP0003705_abnormal_hypodermis_morpholog0.87018848
77MP0002152_abnormal_brain_morphology0.86448885
78MP0005645_abnormal_hypothalamus_physiol0.85939271
79MP0002090_abnormal_vision0.84573268
80MP0000759_abnormal_skeletal_muscle0.80901719
81MP0004147_increased_porphyrin_level0.80632471
82MP0000569_abnormal_digit_pigmentation0.79774840
83MP0002249_abnormal_larynx_morphology0.79700958
84MP0002229_neurodegeneration0.74365141
85MP0001485_abnormal_pinna_reflex0.73584361
86MP0003137_abnormal_impulse_conducting0.72817881
87MP0005394_taste/olfaction_phenotype0.71284901
88MP0005499_abnormal_olfactory_system0.71284901
89MP0000631_abnormal_neuroendocrine_gland0.70957562
90MP0006276_abnormal_autonomic_nervous0.67513193
91MP0004742_abnormal_vestibular_system0.67471335
92MP0004145_abnormal_muscle_electrophysio0.65578352
93MP0003634_abnormal_glial_cell0.63359659
94MP0004087_abnormal_muscle_fiber0.62917666
95MP0001664_abnormal_digestion0.60327077
96MP0004043_abnormal_pH_regulation0.59068543
97MP0003045_fibrosis0.59011254
98MP0002106_abnormal_muscle_physiology0.58398095
99MP0000566_synostosis0.58101322
100MP0005551_abnormal_eye_electrophysiolog0.57916539
101MP0004084_abnormal_cardiac_muscle0.57355295
102MP0005166_decreased_susceptibility_to0.54389344
103MP0003632_abnormal_nervous_system0.53599829
104MP0004484_altered_response_of0.53292685
105MP0005369_muscle_phenotype0.52989809
106MP0001963_abnormal_hearing_physiology0.49733290
107MP0001943_abnormal_respiration0.48516383
108MP0005620_abnormal_muscle_contractility0.48356690
109MP0002752_abnormal_somatic_nervous0.46450965
110MP0004036_abnormal_muscle_relaxation0.45569526
111MP0000604_amyloidosis0.44314461
112* MP0003956_abnormal_body_size0.40880031
113MP0000003_abnormal_adipose_tissue0.40043619
114MP0001299_abnormal_eye_distance/0.39472248
115MP0010769_abnormal_survival0.38955423
116MP0010386_abnormal_urinary_bladder0.37208958
117MP0002082_postnatal_lethality0.36977305
118MP0010770_preweaning_lethality0.36977305
119MP0004215_abnormal_myocardial_fiber0.36778783
120MP0010768_mortality/aging0.36205273
121MP0003122_maternal_imprinting0.36099949
122MP0001765_abnormal_ion_homeostasis0.35432609

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)9.51736924
2Focal motor seizures (HP:0011153)8.21629533
3Focal seizures (HP:0007359)5.83176885
4Resting tremor (HP:0002322)4.54487214
5Annular pancreas (HP:0001734)4.42741606
6Torticollis (HP:0000473)4.41352795
7Poor eye contact (HP:0000817)4.16587463
8Ankle clonus (HP:0011448)4.13128705
9Visual hallucinations (HP:0002367)4.12720868
10Action tremor (HP:0002345)4.10727651
11Diplopia (HP:0000651)3.91783975
12Abnormality of binocular vision (HP:0011514)3.91783975
13Anxiety (HP:0000739)3.90068629
14Broad-based gait (HP:0002136)3.82168256
15Impaired vibration sensation in the lower limbs (HP:0002166)3.79372992
16Focal dystonia (HP:0004373)3.77413314
17Abnormal social behavior (HP:0012433)3.74821866
18Impaired social interactions (HP:0000735)3.74821866
19Epileptic encephalopathy (HP:0200134)3.69735160
20Craniofacial dystonia (HP:0012179)3.68506571
21Febrile seizures (HP:0002373)3.64962585
22Generalized tonic-clonic seizures (HP:0002069)3.62579164
23Depression (HP:0000716)3.59160512
24Dysdiadochokinesis (HP:0002075)3.58427162
25Ankyloglossia (HP:0010296)3.50768238
26Urinary bladder sphincter dysfunction (HP:0002839)3.43156724
27Gaze-evoked nystagmus (HP:0000640)3.35391303
28Absence seizures (HP:0002121)3.34341079
29Lower limb amyotrophy (HP:0007210)3.20210864
30Dialeptic seizures (HP:0011146)3.14754344
31Stereotypic behavior (HP:0000733)3.14126735
32Dysmetria (HP:0001310)3.11372329
33Atonic seizures (HP:0010819)3.09995668
34Postural instability (HP:0002172)3.08477777
35Urinary urgency (HP:0000012)3.04876368
36Prolonged QT interval (HP:0001657)3.02467879
37Pointed chin (HP:0000307)2.98552628
38Dysmetric saccades (HP:0000641)2.95910724
39Tetraplegia (HP:0002445)2.94617707
40Scanning speech (HP:0002168)2.91147688
41Progressive cerebellar ataxia (HP:0002073)2.90866482
42Papilledema (HP:0001085)2.90369989
43Akinesia (HP:0002304)2.88727538
44Overgrowth (HP:0001548)2.78880115
45Supranuclear gaze palsy (HP:0000605)2.78435044
46Atrioventricular block (HP:0001678)2.75767163
47Round ear (HP:0100830)2.75702450
48Abnormal eating behavior (HP:0100738)2.74640304
49Spastic gait (HP:0002064)2.74432147
50Truncal ataxia (HP:0002078)2.74172184
51Distal lower limb amyotrophy (HP:0008944)2.74169878
52Cerebral hypomyelination (HP:0006808)2.74138805
53Polygenic inheritance (HP:0010982)2.72420587
54Abnormal EKG (HP:0003115)2.70101051
55Intention tremor (HP:0002080)2.65776258
56Impaired vibratory sensation (HP:0002495)2.62737067
57Limb dystonia (HP:0002451)2.61414040
58Type 1 muscle fiber predominance (HP:0003803)2.60790581
59Abnormality of oral frenula (HP:0000190)2.55057528
60Impaired smooth pursuit (HP:0007772)2.51261038
61Bradykinesia (HP:0002067)2.48452282
62Hyporeflexia of lower limbs (HP:0002600)2.46455015
63Megalencephaly (HP:0001355)2.45907161
64Hyperventilation (HP:0002883)2.45862663
65Sleep apnea (HP:0010535)2.45211725
66Muscle fiber inclusion bodies (HP:0100299)2.44773274
67Heart block (HP:0012722)2.44436363
68Nemaline bodies (HP:0003798)2.42386014
69Clonus (HP:0002169)2.40624659
70Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.39126748
71Ventricular fibrillation (HP:0001663)2.38998025
72Sudden death (HP:0001699)2.37414404
73Amblyopia (HP:0000646)2.34494695
74Delusions (HP:0000746)2.33533901
75Incomplete penetrance (HP:0003829)2.33215961
76Mutism (HP:0002300)2.31266865
77Progressive inability to walk (HP:0002505)2.30991649
78Muscle fiber splitting (HP:0003555)2.26668179
79Insomnia (HP:0100785)2.25991155
80Lower limb muscle weakness (HP:0007340)2.24566298
81Abnormal atrioventricular conduction (HP:0005150)2.22256890
82Rigidity (HP:0002063)2.18358513
83Abnormality of the lower motor neuron (HP:0002366)2.18143181
84Turricephaly (HP:0000262)2.14505633
85Hemiparesis (HP:0001269)2.12940780
86Status epilepticus (HP:0002133)2.12813687
87Hemiplegia (HP:0002301)2.12716134
88Obstructive sleep apnea (HP:0002870)2.12634682
89Abnormality of ocular smooth pursuit (HP:0000617)2.12453605
90Upper limb amyotrophy (HP:0009129)2.11325291
91Distal upper limb amyotrophy (HP:0007149)2.11325291
92Myopathic facies (HP:0002058)2.10593118
93Bowel incontinence (HP:0002607)2.10120673
94Peripheral hypomyelination (HP:0007182)2.08251033
95Truncus arteriosus (HP:0001660)2.07781670
96Bundle branch block (HP:0011710)2.06452706
97Fetal akinesia sequence (HP:0001989)2.06131009
98Axonal loss (HP:0003447)2.05691953
99Neurofibrillary tangles (HP:0002185)2.04784890
100Aplasia involving bones of the extremities (HP:0009825)2.02904126
101Aplasia involving bones of the upper limbs (HP:0009823)2.02904126
102Aplasia of the phalanges of the hand (HP:0009802)2.02904126
103Onion bulb formation (HP:0003383)2.02493648
104Amelogenesis imperfecta (HP:0000705)2.02449708
105Limb hypertonia (HP:0002509)2.02313022
106Rapidly progressive (HP:0003678)1.97643276
107Syncope (HP:0001279)1.97245501
108Apathy (HP:0000741)1.96691356
109Neuronal loss in central nervous system (HP:0002529)1.94705958
110Termporal pattern (HP:0011008)1.93890453
111Insidious onset (HP:0003587)1.93890453
112Genetic anticipation (HP:0003743)1.93120798
113Abnormal large intestine physiology (HP:0012700)1.92916788
114Lower limb asymmetry (HP:0100559)1.92740355
115Abnormality of saccadic eye movements (HP:0000570)1.91734631
116Drooling (HP:0002307)1.91646007
117Excessive salivation (HP:0003781)1.91646007
118Foot dorsiflexor weakness (HP:0009027)1.90903132
119Exercise-induced muscle cramps (HP:0003710)1.90098155
120Exercise-induced myalgia (HP:0003738)1.89870435
121EMG: myopathic abnormalities (HP:0003458)1.88593952
122Abnormality of the periventricular white matter (HP:0002518)1.88147010
123Primary atrial arrhythmia (HP:0001692)1.87745844
124Bronchomalacia (HP:0002780)1.86622730
125Spinal canal stenosis (HP:0003416)1.85661043
126Atrial fibrillation (HP:0005110)1.85521835
127Dysphonia (HP:0001618)1.85444159
128EEG with generalized epileptiform discharges (HP:0011198)1.83012133
129Epileptiform EEG discharges (HP:0011182)1.82957704
130Cerebral inclusion bodies (HP:0100314)1.82200948
131Abnormality of the foot musculature (HP:0001436)1.79555964
132Myotonia (HP:0002486)1.76306388

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA47.85716483
2NTRK34.13582979
3MAP3K93.33673843
4DAPK22.91069265
5RIPK42.81420810
6KSR22.69055263
7PRKD32.65012999
8CAMKK12.33600012
9MINK12.07473494
10FES1.93441016
11MAP3K131.92275886
12MAP3K41.91093845
13NTRK11.88604326
14NTRK21.86576625
15LATS21.81668027
16PAK61.73650391
17TAOK11.69881510
18ARAF1.68488137
19KSR11.68179787
20TNIK1.66646248
21CDK51.60408075
22MAP3K21.53996640
23MARK11.52234093
24CAMKK21.49370271
25DAPK11.46139253
26SIK21.38165902
27MAP2K71.37555783
28TYRO31.37523075
29PRPF4B1.29231333
30MAPK121.26124833
31PINK11.23387305
32MAP2K41.15900994
33BMPR21.15852169
34STK381.13639356
35RAF11.12896540
36SGK4941.12064955
37SGK2231.12064955
38SGK21.02341435
39PRKCH0.97036903
40OBSCN0.95094571
41TTN0.94570453
42TESK10.94390213
43SGK30.94277226
44PAK30.92805436
45STK110.88750194
46SGK10.87307019
47PRKCG0.87150609
48UHMK10.84755617
49MAP3K10.84496660
50MARK20.82797663
51TNK20.80563688
52CAMK10.80347931
53CDK180.79475830
54CAMK2A0.78985479
55PDPK10.78516962
56CDK150.78400490
57NEK60.76175405
58MAP3K120.75896064
59RIPK10.74061180
60DDR20.73538883
61CAMK2B0.72870337
62CDK140.72853800
63PDK10.72822364
64CASK0.71964371
65GRK50.71185971
66MAP2K60.71146665
67MAPK130.70671485
68RET0.70612165
69PKN10.70444262
70PTK2B0.69190720
71LIMK10.69104975
72NEK10.68641155
73ALK0.68151293
74CDK11A0.67769729
75ROCK10.65869227
76ROCK20.63921886
77PHKG20.59873288
78PHKG10.59873288
79MAP2K10.59494247
80DMPK0.58122928
81EPHA20.57353048
82RPS6KA30.56199817
83LMTK20.56133380
84WNK10.55617726
85MAP3K110.54756288
86FYN0.53965093
87PRKD20.51576214
88CAMK40.50627527
89DAPK30.49601283
90PRKCZ0.48881936
91MAPK100.48268669
92BRSK10.47171061
93PLK20.46944967
94MAPK150.44056792
95CDK190.42533079
96PTK20.42496675
97MOS0.41441141
98CDC42BPA0.41432271
99IRAK20.41398102
100CAMK2G0.39674949
101ICK0.39612782
102CAMK1D0.38785626
103PRKG20.38754516
104PRKCE0.38569813
105PRKCB0.36727844
106ERBB20.36675129
107PRKAA10.36014619
108BRAF0.35520059
109CAMK2D0.35175818
110CAMK1G0.34653570
111MUSK0.34340493
112PDGFRA0.33954567
113CSNK1A10.33521653
114TAOK20.33426170
115MAP3K70.32914685
116FGFR20.32168983
117DYRK1A0.31567818
118OXSR10.31297255
119PRKACA0.31143967
120FGR0.30278282
121TRIB30.28559535
122PRKACG0.28222537
123PRKCA0.26884237
124MAPK80.26334541
125HCK0.26041548

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047403.74288977
2Morphine addiction_Homo sapiens_hsa050322.95061675
3Nicotine addiction_Homo sapiens_hsa050332.93784915
4Amphetamine addiction_Homo sapiens_hsa050312.81988526
5Circadian entrainment_Homo sapiens_hsa047132.76948399
6GABAergic synapse_Homo sapiens_hsa047272.75724195
7Cocaine addiction_Homo sapiens_hsa050302.72301490
8Synaptic vesicle cycle_Homo sapiens_hsa047212.64289412
9Long-term potentiation_Homo sapiens_hsa047202.58928925
10Glutamatergic synapse_Homo sapiens_hsa047242.53284475
11Dopaminergic synapse_Homo sapiens_hsa047282.43779570
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.40356986
13Cholinergic synapse_Homo sapiens_hsa047252.22621491
14Salivary secretion_Homo sapiens_hsa049702.08626414
15Renin secretion_Homo sapiens_hsa049242.02601738
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.91703327
17Gastric acid secretion_Homo sapiens_hsa049711.84415151
18Oxytocin signaling pathway_Homo sapiens_hsa049211.81975446
19Calcium signaling pathway_Homo sapiens_hsa040201.78516688
20Insulin secretion_Homo sapiens_hsa049111.76157904
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.74574356
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.73006124
23Serotonergic synapse_Homo sapiens_hsa047261.63508826
24Nitrogen metabolism_Homo sapiens_hsa009101.62177295
25Gap junction_Homo sapiens_hsa045401.58142851
26Long-term depression_Homo sapiens_hsa047301.54421920
27GnRH signaling pathway_Homo sapiens_hsa049121.47885904
28Taste transduction_Homo sapiens_hsa047421.45717839
29cAMP signaling pathway_Homo sapiens_hsa040241.43136260
30Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.31106662
31Vitamin B6 metabolism_Homo sapiens_hsa007501.25536575
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20813105
33Glioma_Homo sapiens_hsa052141.12962026
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.11916093
35Vascular smooth muscle contraction_Homo sapiens_hsa042701.09702076
36cGMP-PKG signaling pathway_Homo sapiens_hsa040221.08115922
37Type II diabetes mellitus_Homo sapiens_hsa049301.03007340
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.01885302
39Phototransduction_Homo sapiens_hsa047441.00888652
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.99904754
41Estrogen signaling pathway_Homo sapiens_hsa049150.99261011
42Melanogenesis_Homo sapiens_hsa049160.97596664
43Phospholipase D signaling pathway_Homo sapiens_hsa040720.96860854
44Alcoholism_Homo sapiens_hsa050340.90091445
45ErbB signaling pathway_Homo sapiens_hsa040120.90051539
46Dilated cardiomyopathy_Homo sapiens_hsa054140.86776809
47Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85700623
48Oocyte meiosis_Homo sapiens_hsa041140.84172577
49Axon guidance_Homo sapiens_hsa043600.84020826
50Dorso-ventral axis formation_Homo sapiens_hsa043200.83932294
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83810145
52Cardiac muscle contraction_Homo sapiens_hsa042600.82453658
53Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81386521
54Non-small cell lung cancer_Homo sapiens_hsa052230.79992954
55Rap1 signaling pathway_Homo sapiens_hsa040150.79007524
56Pancreatic secretion_Homo sapiens_hsa049720.78929286
57Collecting duct acid secretion_Homo sapiens_hsa049660.78834813
58Type I diabetes mellitus_Homo sapiens_hsa049400.76436437
59MAPK signaling pathway_Homo sapiens_hsa040100.70300346
60Thyroid hormone synthesis_Homo sapiens_hsa049180.69759317
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.68299259
62Choline metabolism in cancer_Homo sapiens_hsa052310.68192700
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63830569
64VEGF signaling pathway_Homo sapiens_hsa043700.61950811
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61821587
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60165738
67Chemokine signaling pathway_Homo sapiens_hsa040620.60140219
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.59633741
69Ras signaling pathway_Homo sapiens_hsa040140.57652526
70Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56492449
71Sphingolipid signaling pathway_Homo sapiens_hsa040710.53780702
72mTOR signaling pathway_Homo sapiens_hsa041500.49669730
73Glucagon signaling pathway_Homo sapiens_hsa049220.49593089
74Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49581976
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48654074
76Bile secretion_Homo sapiens_hsa049760.48311142
77Circadian rhythm_Homo sapiens_hsa047100.48007444
78Tight junction_Homo sapiens_hsa045300.45723278
79Endocytosis_Homo sapiens_hsa041440.45236844
80African trypanosomiasis_Homo sapiens_hsa051430.44624218
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44338135
82ECM-receptor interaction_Homo sapiens_hsa045120.42936859
83Inositol phosphate metabolism_Homo sapiens_hsa005620.42759153
842-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.42425431
85Platelet activation_Homo sapiens_hsa046110.42063294
86Vibrio cholerae infection_Homo sapiens_hsa051100.41806859
87Ovarian steroidogenesis_Homo sapiens_hsa049130.41576529
88Arginine and proline metabolism_Homo sapiens_hsa003300.41216271
89Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.41176939
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41137331
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41134025
92Prion diseases_Homo sapiens_hsa050200.40781721
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40320514
94Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38948735
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.38946294
96Endometrial cancer_Homo sapiens_hsa052130.38707259
97AMPK signaling pathway_Homo sapiens_hsa041520.36752555
98Renal cell carcinoma_Homo sapiens_hsa052110.35397518
99Hippo signaling pathway_Homo sapiens_hsa043900.34610869
100Insulin signaling pathway_Homo sapiens_hsa049100.34161632
101Protein digestion and absorption_Homo sapiens_hsa049740.32964242
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32765197
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30931541
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.30613111
105Thyroid cancer_Homo sapiens_hsa052160.30502131
106Focal adhesion_Homo sapiens_hsa045100.30064205
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27203655
108Wnt signaling pathway_Homo sapiens_hsa043100.26675180
109Arginine biosynthesis_Homo sapiens_hsa002200.24913990
110Sulfur relay system_Homo sapiens_hsa041220.24259003
111Amoebiasis_Homo sapiens_hsa051460.23294941
112Mineral absorption_Homo sapiens_hsa049780.22028117
113Alzheimers disease_Homo sapiens_hsa050100.20984285

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