RASGEF1A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.22286960
2locomotory exploration behavior (GO:0035641)6.11770241
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.04452796
4synaptic vesicle maturation (GO:0016188)5.97296191
5vocalization behavior (GO:0071625)5.56735471
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.42673225
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.37128809
8synaptic vesicle exocytosis (GO:0016079)5.29610352
9regulation of glutamate receptor signaling pathway (GO:1900449)5.17997897
10synaptic vesicle docking involved in exocytosis (GO:0016081)5.12497301
11glutamate secretion (GO:0014047)4.99213487
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.97828063
13regulation of long-term neuronal synaptic plasticity (GO:0048169)4.94532123
14regulation of synaptic vesicle exocytosis (GO:2000300)4.93041726
15regulation of neuronal synaptic plasticity (GO:0048168)4.85878446
16regulation of synapse structural plasticity (GO:0051823)4.79190231
17neuronal action potential propagation (GO:0019227)4.77734605
18protein localization to synapse (GO:0035418)4.76848479
19exploration behavior (GO:0035640)4.60749873
20L-amino acid import (GO:0043092)4.50375286
21regulation of synaptic vesicle transport (GO:1902803)4.46581813
22synaptic transmission, glutamatergic (GO:0035249)4.39501312
23neurotransmitter secretion (GO:0007269)4.38373242
24glutamate receptor signaling pathway (GO:0007215)4.35394864
25regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.26269143
26neurotransmitter-gated ion channel clustering (GO:0072578)4.25520319
27neuron-neuron synaptic transmission (GO:0007270)4.25353134
28long-term memory (GO:0007616)4.25090909
29lactate metabolic process (GO:0006089)4.24753376
30dendritic spine morphogenesis (GO:0060997)4.23947450
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.21511310
32regulation of excitatory postsynaptic membrane potential (GO:0060079)4.18066376
33regulation of dendritic spine morphogenesis (GO:0061001)4.10245900
34positive regulation of membrane potential (GO:0045838)4.04116241
35amino acid import (GO:0043090)4.02443888
36neuron cell-cell adhesion (GO:0007158)4.01838150
37layer formation in cerebral cortex (GO:0021819)3.99442749
38regulation of postsynaptic membrane potential (GO:0060078)3.91621377
39regulation of synaptic plasticity (GO:0048167)3.91166486
40serotonin metabolic process (GO:0042428)3.77583766
41gamma-aminobutyric acid transport (GO:0015812)3.76193289
42G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.75505274
43neuromuscular process controlling balance (GO:0050885)3.74126468
44prepulse inhibition (GO:0060134)3.73859653
45positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.73080435
46positive regulation of synaptic transmission, GABAergic (GO:0032230)3.70439573
47long-term synaptic potentiation (GO:0060291)3.70041002
48negative regulation of dendrite morphogenesis (GO:0050774)3.67905925
49cellular potassium ion homeostasis (GO:0030007)3.67067305
50positive regulation of neurotransmitter transport (GO:0051590)3.66506421
51positive regulation of neurotransmitter secretion (GO:0001956)3.66190052
52proline transport (GO:0015824)3.63214845
53transmission of nerve impulse (GO:0019226)3.63160600
54regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.62512269
55activation of protein kinase A activity (GO:0034199)3.62354915
56regulation of synaptic transmission, glutamatergic (GO:0051966)3.58234859
57auditory behavior (GO:0031223)3.54433722
58neurotransmitter transport (GO:0006836)3.51703673
59positive regulation of synapse maturation (GO:0090129)3.49451203
60potassium ion homeostasis (GO:0055075)3.49447028
61regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.48775813
62positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.43155819
63regulation of neurotransmitter secretion (GO:0046928)3.41766831
64behavioral defense response (GO:0002209)3.41370776
65behavioral fear response (GO:0001662)3.41370776
66synaptic transmission, dopaminergic (GO:0001963)3.39461693
67regulation of dendritic spine development (GO:0060998)3.38909157
68regulation of female receptivity (GO:0045924)3.38645077
69behavioral response to cocaine (GO:0048148)3.38066438
70cerebellar granule cell differentiation (GO:0021707)3.38036369
71negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.35519280
72regulation of glutamate secretion (GO:0014048)3.35146383
73gamma-aminobutyric acid signaling pathway (GO:0007214)3.34840652
74dendritic spine organization (GO:0097061)3.34241722
75regulation of vesicle fusion (GO:0031338)3.34038784
76response to auditory stimulus (GO:0010996)3.32654238
77regulation of neurotransmitter levels (GO:0001505)3.32135184
78neuronal ion channel clustering (GO:0045161)3.31923538
79neuron recognition (GO:0008038)3.31415298
80membrane depolarization (GO:0051899)3.31391343
81sodium ion export (GO:0071436)3.30819571
82synaptic vesicle endocytosis (GO:0048488)3.30077675
83neuromuscular process controlling posture (GO:0050884)3.28330191
84response to histamine (GO:0034776)3.26488957
85regulation of neurotransmitter transport (GO:0051588)3.25264139
86negative regulation of synaptic transmission, GABAergic (GO:0032229)3.24383366
87striatum development (GO:0021756)3.23567716
88learning (GO:0007612)3.19198876
89positive regulation of synaptic transmission (GO:0050806)3.19187471
90positive regulation of dendritic spine development (GO:0060999)3.19028070
91regulation of dopamine metabolic process (GO:0042053)3.18575289
92regulation of catecholamine metabolic process (GO:0042069)3.18575289
93fear response (GO:0042596)3.18235885
94membrane hyperpolarization (GO:0060081)3.18061980
95membrane depolarization during action potential (GO:0086010)3.14884425
96G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.14829322
97regulation of voltage-gated calcium channel activity (GO:1901385)3.12746834
98vesicle transport along microtubule (GO:0047496)3.11585699
99cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.11268812
100regulation of synaptic transmission (GO:0050804)3.09283688
101glycine transport (GO:0015816)3.08768910
102response to amphetamine (GO:0001975)3.08303549
103negative regulation of amino acid transport (GO:0051956)3.05614449
104neuromuscular process (GO:0050905)3.05428429
105female mating behavior (GO:0060180)3.04745242
106cerebellar Purkinje cell differentiation (GO:0021702)3.03901422
107positive regulation of dendritic spine morphogenesis (GO:0061003)3.01848917
108synaptic transmission (GO:0007268)3.01302890
109axonal fasciculation (GO:0007413)3.00768765
110long term synaptic depression (GO:0060292)2.99143600
111dopamine receptor signaling pathway (GO:0007212)2.98857216
112neurotransmitter uptake (GO:0001504)2.98066122
113primary amino compound metabolic process (GO:1901160)2.97966755
114protein complex localization (GO:0031503)2.95855359
115negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.94354336
116social behavior (GO:0035176)2.93519512
117intraspecies interaction between organisms (GO:0051703)2.93519512
118regulation of ARF protein signal transduction (GO:0032012)2.93122028
119hyperosmotic salinity response (GO:0042538)2.92723421
120chaperone-mediated protein transport (GO:0072321)2.91477786
121regulation of Golgi to plasma membrane protein transport (GO:0042996)2.90874394
122acidic amino acid transport (GO:0015800)2.81533845
123detection of calcium ion (GO:0005513)2.78308464
124negative regulation of dendrite development (GO:2000171)2.78298754
125regulation of exocytosis (GO:0017157)2.78129670
126sleep (GO:0030431)2.77591970
127phosphorelay signal transduction system (GO:0000160)2.77249912
128potassium ion import (GO:0010107)2.74206192
129cell communication by electrical coupling (GO:0010644)2.73791344
130establishment of synaptic vesicle localization (GO:0097480)2.73481849
131synaptic vesicle transport (GO:0048489)2.73481849
132regulation of mitochondrial translation (GO:0070129)2.73220601
133IMP biosynthetic process (GO:0006188)2.71525123
134cell communication involved in cardiac conduction (GO:0086065)2.70191883
135establishment of integrated proviral latency (GO:0075713)2.63653368
136vesicle docking involved in exocytosis (GO:0006904)2.60262206
137signal release (GO:0023061)2.58427822
138transcription from mitochondrial promoter (GO:0006390)2.57872222
139response to insecticide (GO:0017085)2.55891323
140regulation of oxidative phosphorylation (GO:0002082)2.53975349
141L-glutamate transport (GO:0015813)2.53865457
142regulation of calcium ion-dependent exocytosis (GO:0017158)2.52245598

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.07947855
2E2F7_22180533_ChIP-Seq_HELA_Human4.35051454
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.36292170
4GBX2_23144817_ChIP-Seq_PC3_Human3.32034897
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.24122954
6RARB_27405468_Chip-Seq_BRAIN_Mouse3.18247755
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.16154297
8JARID2_20064375_ChIP-Seq_MESCs_Mouse3.14582975
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.03373783
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.84270799
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.84270799
12* REST_21632747_ChIP-Seq_MESCs_Mouse2.81404669
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.75816495
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.73544039
15DROSHA_22980978_ChIP-Seq_HELA_Human2.71142246
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.63873328
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.61601719
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.57967028
19THAP11_20581084_ChIP-Seq_MESCs_Mouse2.51944941
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.51667312
21GATA1_26923725_Chip-Seq_HPCs_Mouse2.49072903
22* EZH2_27304074_Chip-Seq_ESCs_Mouse2.42654764
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.39057773
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.38511785
25MYC_18555785_ChIP-Seq_MESCs_Mouse2.37237077
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.34424537
27SUZ12_27294783_Chip-Seq_ESCs_Mouse2.33310658
28REST_18959480_ChIP-ChIP_MESCs_Mouse2.31038173
29EZH2_27294783_Chip-Seq_ESCs_Mouse2.28006795
30SIN3A_21632747_ChIP-Seq_MESCs_Mouse2.23765503
31EED_16625203_ChIP-ChIP_MESCs_Mouse2.23053351
32RNF2_27304074_Chip-Seq_ESCs_Mouse2.22720444
33EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.04083432
34NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.01137368
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.97721233
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.97086690
37MYC_19079543_ChIP-ChIP_MESCs_Mouse1.94150756
38CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.89846095
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.85533418
40AR_21572438_ChIP-Seq_LNCaP_Human1.84233558
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.82516026
42JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.82110881
43EST1_17652178_ChIP-ChIP_JURKAT_Human1.79225490
44ERG_21242973_ChIP-ChIP_JURKAT_Human1.78829089
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.77959978
46NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.77941809
47ETS1_20019798_ChIP-Seq_JURKAT_Human1.74614701
48MYC_18358816_ChIP-ChIP_MESCs_Mouse1.67054825
49MYC_19030024_ChIP-ChIP_MESCs_Mouse1.61798097
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.59393396
51SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58649926
52SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.58232954
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.56246621
54CREB1_15753290_ChIP-ChIP_HEK293T_Human1.55807517
55SMAD4_21799915_ChIP-Seq_A2780_Human1.55635874
56YY1_21170310_ChIP-Seq_MESCs_Mouse1.53372396
57GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.53091297
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.49603047
59CTBP1_25329375_ChIP-Seq_LNCAP_Human1.48501954
60TAF15_26573619_Chip-Seq_HEK293_Human1.47674059
61CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.46887670
62KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.43374036
63ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.40389840
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.38484771
65RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.37619290
66KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37455175
67DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35117500
68E2F4_17652178_ChIP-ChIP_JURKAT_Human1.33885511
69NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.33238654
70RING1B_27294783_Chip-Seq_ESCs_Mouse1.33119437
71NANOG_18555785_ChIP-Seq_MESCs_Mouse1.31602574
72SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30271541
73ZFX_18555785_ChIP-Seq_MESCs_Mouse1.30155279
74TTF2_22483619_ChIP-Seq_HELA_Human1.29180558
75CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28396190
76CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.28035647
77SOX2_21211035_ChIP-Seq_LN229_Gbm1.25958055
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25900165
79NR3C1_23031785_ChIP-Seq_PC12_Mouse1.24129891
80NELFA_20434984_ChIP-Seq_ESCs_Mouse1.23602047
81SMAD_19615063_ChIP-ChIP_OVARY_Human1.23343620
82YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.23182363
83WT1_25993318_ChIP-Seq_PODOCYTE_Human1.22675544
84PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22667102
85SMAD3_21741376_ChIP-Seq_EPCs_Human1.22595792
86PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.21642146
87CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.21600276
88PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21435015
89P300_19829295_ChIP-Seq_ESCs_Human1.20546946
90AR_19668381_ChIP-Seq_PC3_Human1.19599848
91KDM2B_26808549_Chip-Seq_K562_Human1.17599825
92ZNF274_21170338_ChIP-Seq_K562_Hela1.16880220
93TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.16480617
94WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.16175343
95AR_25329375_ChIP-Seq_VCAP_Human1.16172551
96ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15312530
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14847139
98STAT3_23295773_ChIP-Seq_U87_Human1.14689390
99ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.14507890
100* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13724245
101P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12641320
102FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.11489149
103NANOG_16518401_ChIP-PET_MESCs_Mouse1.11134005
104RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10547871
105KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.10197381
106KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.10197381
107KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.10197381
108RING1B_27294783_Chip-Seq_NPCs_Mouse1.10157795
109ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.09937984
110GABP_17652178_ChIP-ChIP_JURKAT_Human1.09883568
111ZFP281_18757296_ChIP-ChIP_E14_Mouse1.09175012
112GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08615142
113TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08470933
114GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.07289821
115ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05442057
116TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05225520
117OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03313153
118TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02582805
119PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01784790
120SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01106164
121FOXM1_23109430_ChIP-Seq_U2OS_Human1.01006620
122ARNT_22903824_ChIP-Seq_MCF-7_Human1.00183206
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.99730558
124GABP_19822575_ChIP-Seq_HepG2_Human0.99724121
125SALL1_21062744_ChIP-ChIP_HESCs_Human0.99592191
126STAT3_1855785_ChIP-Seq_MESCs_Mouse0.99254396
127* TCF4_23295773_ChIP-Seq_U87_Human0.99184382
128MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98634892
129VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.98586738
130CBX2_27304074_Chip-Seq_ESCs_Mouse0.98510407
131NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.98373267
132AHR_22903824_ChIP-Seq_MCF-7_Human0.98112124
133CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.98075147
134TP53_16413492_ChIP-PET_HCT116_Human0.97390396
135SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96870517
136PIAS1_25552417_ChIP-Seq_VCAP_Human0.96647645
137FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.96581261
138CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96531427
139YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96498246
140FOXP3_21729870_ChIP-Seq_TREG_Human0.96446325
141RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96148242
142SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.94633670
143E2F1_18555785_ChIP-Seq_MESCs_Mouse0.94419231
144PRDM14_20953172_ChIP-Seq_ESCs_Human0.93966186
145TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.93048764
146BMI1_23680149_ChIP-Seq_NPCS_Mouse0.92919688
147THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.92299056
148RUNX1_26923725_Chip-Seq_HPCs_Mouse0.91479180
149SMAD3_21741376_ChIP-Seq_ESCs_Human0.91443798
150TBX5_21415370_ChIP-Seq_HL-1_Mouse0.90589569
151SMAD4_21741376_ChIP-Seq_HESCs_Human0.90292183
152NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89988177
153CTCF_27219007_Chip-Seq_Bcells_Human0.89592978
154* RUNX2_22187159_ChIP-Seq_PCA_Human0.89444067
155OCT4_19829295_ChIP-Seq_ESCs_Human0.89215184
156RXR_22108803_ChIP-Seq_LS180_Human0.89187679
157BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.86403618
158CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.85987764
159FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85774403
160TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.84992500
161UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84897821
162* TET1_21490601_ChIP-Seq_MESCs_Mouse0.84866705
163SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.84756771
164ZFP281_27345836_Chip-Seq_ESCs_Mouse0.84741968
165NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.84479992
166KDM5A_27292631_Chip-Seq_BREAST_Human0.84466438
167TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.84390565
168RNF2_27304074_Chip-Seq_NSC_Mouse0.84346336
169XRN2_22483619_ChIP-Seq_HELA_Human0.84057608
170TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.83911860
171AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.83862102
172ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.80705910
173SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80329645

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.28676693
2MP0003880_abnormal_central_pattern4.96458265
3MP0002822_catalepsy4.57022647
4MP0003635_abnormal_synaptic_transmissio4.40230808
5MP0009745_abnormal_behavioral_response3.74175216
6MP0004270_analgesia3.72851866
7MP0002063_abnormal_learning/memory/cond3.58961951
8MP0002064_seizures3.34396461
9MP0008877_abnormal_DNA_methylation3.22908102
10MP0001968_abnormal_touch/_nociception3.06910158
11MP0009046_muscle_twitch3.04671286
12MP0002572_abnormal_emotion/affect_behav2.93048298
13MP0002272_abnormal_nervous_system2.72775292
14MP0001486_abnormal_startle_reflex2.65211181
15MP0002734_abnormal_mechanical_nocicepti2.50392744
16MP0001501_abnormal_sleep_pattern2.49906322
17MP0005423_abnormal_somatic_nervous2.49440738
18MP0002736_abnormal_nociception_after2.35024217
19MP0001440_abnormal_grooming_behavior2.14956137
20MP0002735_abnormal_chemical_nociception2.05322293
21MP0008058_abnormal_DNA_repair2.03881761
22MP0003123_paternal_imprinting2.01870342
23MP0001970_abnormal_pain_threshold1.95082380
24MP0009780_abnormal_chondrocyte_physiolo1.94554021
25MP0008569_lethality_at_weaning1.92966163
26MP0002733_abnormal_thermal_nociception1.92517735
27MP0002909_abnormal_adrenal_gland1.87740277
28MP0002067_abnormal_sensory_capabilities1.83008244
29MP0003329_amyloid_beta_deposits1.80065725
30MP0003693_abnormal_embryo_hatching1.75696915
31MP0004811_abnormal_neuron_physiology1.75014509
32MP0006035_abnormal_mitochondrial_morpho1.71861297
33MP0004924_abnormal_behavior1.71383504
34MP0005386_behavior/neurological_phenoty1.71383504
35MP0002557_abnormal_social/conspecific_i1.70000562
36MP0005646_abnormal_pituitary_gland1.68334886
37MP0004957_abnormal_blastocyst_morpholog1.66051958
38MP0004858_abnormal_nervous_system1.64446502
39MP0003879_abnormal_hair_cell1.62868521
40MP0002254_reproductive_system_inflammat1.60450773
41MP0008057_abnormal_DNA_replication1.58128070
42MP0001529_abnormal_vocalization1.57794933
43MP0002184_abnormal_innervation1.57274793
44MP0000778_abnormal_nervous_system1.46571275
45MP0000955_abnormal_spinal_cord1.41841968
46MP0003633_abnormal_nervous_system1.41645670
47MP0004885_abnormal_endolymph1.40114966
48MP0002066_abnormal_motor_capabilities/c1.39872929
49MP0010094_abnormal_chromosome_stability1.37427945
50MP0001984_abnormal_olfaction1.33312537
51MP0003121_genomic_imprinting1.33210843
52MP0003787_abnormal_imprinting1.31328587
53MP0002882_abnormal_neuron_morphology1.29995008
54MP0003111_abnormal_nucleus_morphology1.29292433
55MP0003075_altered_response_to1.28067350
56MP0001905_abnormal_dopamine_level1.23778645
57MP0006036_abnormal_mitochondrial_physio1.23391417
58MP0006276_abnormal_autonomic_nervous1.18623405
59MP0003631_nervous_system_phenotype1.16009069
60MP0001502_abnormal_circadian_rhythm1.13768876
61MP0008872_abnormal_physiological_respon1.13648760
62MP0004142_abnormal_muscle_tone1.12889743
63MP0008874_decreased_physiological_sensi1.12817633
64MP0001188_hyperpigmentation1.10275698
65MP0005167_abnormal_blood-brain_barrier1.09842033
66MP0001177_atelectasis1.07229864
67MP0005645_abnormal_hypothalamus_physiol1.06122539
68MP0009672_abnormal_birth_weight1.01753404
69MP0003890_abnormal_embryonic-extraembry1.01570787
70MP0001346_abnormal_lacrimal_gland1.00436458
71MP0005409_darkened_coat_color1.00280493
72MP0002152_abnormal_brain_morphology0.98835938
73MP0000678_abnormal_parathyroid_gland0.98792602
74MP0008961_abnormal_basal_metabolism0.98172138
75MP0003718_maternal_effect0.97975177
76MP0002069_abnormal_eating/drinking_beha0.96245697
77MP0000751_myopathy0.94715109
78MP0000013_abnormal_adipose_tissue0.94371361
79MP0005535_abnormal_body_temperature0.94268549
80MP0003077_abnormal_cell_cycle0.93438521
81MP0003690_abnormal_glial_cell0.91432913
82MP0006292_abnormal_olfactory_placode0.89600660
83MP0001730_embryonic_growth_arrest0.89050496
84MP0003283_abnormal_digestive_organ0.88672307
85MP0004085_abnormal_heartbeat0.87943753
86MP0000920_abnormal_myelination0.86456693
87MP0002693_abnormal_pancreas_physiology0.86454504
88MP0002229_neurodegeneration0.86087249
89MP0000604_amyloidosis0.83784355
90MP0010234_abnormal_vibrissa_follicle0.83068901
91MP0001929_abnormal_gametogenesis0.82592453
92MP0002210_abnormal_sex_determination0.82194253
93MP0003122_maternal_imprinting0.81747270
94MP0004510_myositis0.80295680
95MP0004145_abnormal_muscle_electrophysio0.80198843
96MP0003698_abnormal_male_reproductive0.75742359
97MP0003634_abnormal_glial_cell0.75130972
98MP0010386_abnormal_urinary_bladder0.74805532
99MP0002090_abnormal_vision0.74563425
100MP0000569_abnormal_digit_pigmentation0.74450909
101MP0003632_abnormal_nervous_system0.73631313
102MP0005551_abnormal_eye_electrophysiolog0.71260989
103MP0008932_abnormal_embryonic_tissue0.69648314
104MP0001664_abnormal_digestion0.69570196
105MP0001986_abnormal_taste_sensitivity0.69428344
106MP0004742_abnormal_vestibular_system0.69128796
107MP0003119_abnormal_digestive_system0.68414141
108MP0002161_abnormal_fertility/fecundity0.68210490
109MP0001963_abnormal_hearing_physiology0.67151892
110MP0000579_abnormal_nail_morphology0.67108718
111MP0005394_taste/olfaction_phenotype0.66456279
112MP0005499_abnormal_olfactory_system0.66456279
113MP0008260_abnormal_autophagy0.64902526
114MP0002873_normal_phenotype0.64457382
115MP0001145_abnormal_male_reproductive0.63851616
116MP0002169_no_abnormal_phenotype0.63455577
117MP0004484_altered_response_of0.62647023
118MP0003806_abnormal_nucleotide_metabolis0.61944347
119MP0002796_impaired_skin_barrier0.61485321
120MP0003786_premature_aging0.60447691
121MP0002837_dystrophic_cardiac_calcinosis0.60107159
122MP0004215_abnormal_myocardial_fiber0.57948431
123MP0001485_abnormal_pinna_reflex0.56408335
124MP0002752_abnormal_somatic_nervous0.56237173
125MP0005623_abnormal_meninges_morphology0.56069690
126MP0003137_abnormal_impulse_conducting0.55868795
127MP0000631_abnormal_neuroendocrine_gland0.55225504
128MP0005166_decreased_susceptibility_to0.53362296
129MP0004043_abnormal_pH_regulation0.53197640
130MP0001943_abnormal_respiration0.51445306
131MP0003172_abnormal_lysosome_physiology0.50304559
132MP0004233_abnormal_muscle_weight0.48919671
133MP0002876_abnormal_thyroid_physiology0.48652538
134MP0003956_abnormal_body_size0.47625363
135MP0001765_abnormal_ion_homeostasis0.47343788
136MP0010769_abnormal_survival0.46154536

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.55658055
2Myokymia (HP:0002411)8.37793047
3Focal seizures (HP:0007359)6.24862342
4Visual hallucinations (HP:0002367)5.39970734
5Epileptic encephalopathy (HP:0200134)4.75203466
6Atonic seizures (HP:0010819)4.74730482
7Febrile seizures (HP:0002373)4.56114279
8Action tremor (HP:0002345)4.36401646
9Absence seizures (HP:0002121)4.34435897
10Cerebral hypomyelination (HP:0006808)4.22006774
11Progressive cerebellar ataxia (HP:0002073)4.10693990
12Generalized tonic-clonic seizures (HP:0002069)4.07680367
13Dialeptic seizures (HP:0011146)4.00784563
14Poor eye contact (HP:0000817)3.82646487
15Impaired vibration sensation in the lower limbs (HP:0002166)3.77375518
16Broad-based gait (HP:0002136)3.67005858
17Gaze-evoked nystagmus (HP:0000640)3.54067092
18Depression (HP:0000716)3.48269639
19Ankle clonus (HP:0011448)3.46123822
20Anxiety (HP:0000739)3.44269190
21Dysdiadochokinesis (HP:0002075)3.44162029
22Impaired social interactions (HP:0000735)3.43876385
23Abnormal social behavior (HP:0012433)3.43876385
24Supranuclear gaze palsy (HP:0000605)3.43369335
25Dysmetria (HP:0001310)3.38646435
26Hypoglycemic seizures (HP:0002173)3.33706331
27Annular pancreas (HP:0001734)3.24831162
28Urinary bladder sphincter dysfunction (HP:0002839)3.20016970
29Hyperinsulinemic hypoglycemia (HP:0000825)3.16393816
30Postural instability (HP:0002172)3.15018222
31Amblyopia (HP:0000646)3.12099113
32Hyperventilation (HP:0002883)3.08176518
33Papilledema (HP:0001085)3.06970029
34Torticollis (HP:0000473)3.06625717
35Tetraplegia (HP:0002445)3.03729340
36Truncal ataxia (HP:0002078)3.01073344
37Abnormal eating behavior (HP:0100738)2.95376802
38Abnormality of the lower motor neuron (HP:0002366)2.91702450
39Focal dystonia (HP:0004373)2.87137948
40Impaired smooth pursuit (HP:0007772)2.83441184
41Urinary urgency (HP:0000012)2.82684687
42Stereotypic behavior (HP:0000733)2.79728226
43Abnormality of the labia minora (HP:0012880)2.78222162
44Scanning speech (HP:0002168)2.77375416
45Intention tremor (HP:0002080)2.71136156
46Mutism (HP:0002300)2.69160862
47Resting tremor (HP:0002322)2.68744017
48Cerebral inclusion bodies (HP:0100314)2.62583150
49Bradykinesia (HP:0002067)2.60660850
50Neurofibrillary tangles (HP:0002185)2.58130784
51Spastic gait (HP:0002064)2.57030692
52Dysmetric saccades (HP:0000641)2.56704678
53Impaired vibratory sensation (HP:0002495)2.56613823
54Peripheral hypomyelination (HP:0007182)2.56350274
55Choreoathetosis (HP:0001266)2.56189179
56CNS hypomyelination (HP:0003429)2.55503826
57Craniofacial dystonia (HP:0012179)2.55226350
58Ventricular fibrillation (HP:0001663)2.53899703
59Hemiparesis (HP:0001269)2.51790702
60Progressive inability to walk (HP:0002505)2.48309277
61Genetic anticipation (HP:0003743)2.47372572
62Status epilepticus (HP:0002133)2.47352300
63Hemiplegia (HP:0002301)2.44116474
64Diplopia (HP:0000651)2.42826587
65Abnormality of binocular vision (HP:0011514)2.42826587
66Abnormality of ocular smooth pursuit (HP:0000617)2.42371400
67Drooling (HP:0002307)2.41376287
68Excessive salivation (HP:0003781)2.41376287
69Megalencephaly (HP:0001355)2.39384916
70Pointed chin (HP:0000307)2.37023195
71Hypoglycemic coma (HP:0001325)2.30617830
72Ankyloglossia (HP:0010296)2.29331821
73Termporal pattern (HP:0011008)2.26499966
74Insidious onset (HP:0003587)2.26499966
75Epileptiform EEG discharges (HP:0011182)2.25264942
76Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.20443744
77Degeneration of the lateral corticospinal tracts (HP:0002314)2.20443744
78Abnormality of glycolysis (HP:0004366)2.19184283
79Incomplete penetrance (HP:0003829)2.15903666
80Absent speech (HP:0001344)2.15348430
81Lower limb muscle weakness (HP:0007340)2.14981759
82EEG with generalized epileptiform discharges (HP:0011198)2.12991122
83Agnosia (HP:0010524)2.11545444
84Generalized myoclonic seizures (HP:0002123)2.11378533
85Lower limb amyotrophy (HP:0007210)2.10357054
86Fetal akinesia sequence (HP:0001989)2.10280395
87Birth length less than 3rd percentile (HP:0003561)2.09575694
88Bundle branch block (HP:0011710)2.08573640
89Multiple enchondromatosis (HP:0005701)2.06170382
90Horizontal nystagmus (HP:0000666)2.05064012
91Neuronal loss in central nervous system (HP:0002529)2.05028955
92Gait ataxia (HP:0002066)2.04441941
93Increased circulating renin level (HP:0000848)2.04208016
94Dysphonia (HP:0001618)2.03297584
95Hypsarrhythmia (HP:0002521)2.02200839
96Lower limb asymmetry (HP:0100559)2.01204323
97Congenital malformation of the right heart (HP:0011723)2.00177407
98Double outlet right ventricle (HP:0001719)2.00177407
99Hypokinesia (HP:0002375)1.99899157
100Abnormal EKG (HP:0003115)1.99530132
101Symptomatic seizures (HP:0011145)1.99479926
102Inability to walk (HP:0002540)1.99238825
103Delusions (HP:0000746)1.97337337
104Leukodystrophy (HP:0002415)1.96403967
105Clonus (HP:0002169)1.95861110
106Abnormality of saccadic eye movements (HP:0000570)1.95137323
107Obstructive sleep apnea (HP:0002870)1.93332384
108Truncus arteriosus (HP:0001660)1.92060503
109Rapidly progressive (HP:0003678)1.91928429
110Abnormality of the periventricular white matter (HP:0002518)1.91706490
111Abnormality of the pancreatic islet cells (HP:0006476)1.89978791
112Abnormality of endocrine pancreas physiology (HP:0012093)1.89978791
113Increased serum pyruvate (HP:0003542)1.89887297
114Psychosis (HP:0000709)1.89016220
115Pancreatic islet-cell hyperplasia (HP:0004510)1.88256563
116Sleep apnea (HP:0010535)1.88011395
117Ependymoma (HP:0002888)1.87477573
118Rigidity (HP:0002063)1.86303192
119Insomnia (HP:0100785)1.86073361
120Muscular hypotonia of the trunk (HP:0008936)1.85448085
121Pheochromocytoma (HP:0002666)1.84222289
122Limb dystonia (HP:0002451)1.81932048
123Abnormality of the corticospinal tract (HP:0002492)1.80406898
124Akinesia (HP:0002304)1.80282716
125Blue irides (HP:0000635)1.79198976
126Volvulus (HP:0002580)1.77176159
127Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.75218225
128Spinal canal stenosis (HP:0003416)1.74742147
129Poor speech (HP:0002465)1.74082075
130Sensory axonal neuropathy (HP:0003390)1.73579829
131Abnormal gallbladder physiology (HP:0012438)1.73499465
132Cholecystitis (HP:0001082)1.73499465
133Acute necrotizing encephalopathy (HP:0006965)1.72906584
134Abnormality of aromatic amino acid family metabolism (HP:0004338)1.71538256
135Prominent metopic ridge (HP:0005487)1.70723971
136Prolonged QT interval (HP:0001657)1.70509928
137Abnormality of oral frenula (HP:0000190)1.68074695
138Abnormality of salivation (HP:0100755)1.66733672
139Polyphagia (HP:0002591)1.66066581
140Deep palmar crease (HP:0006191)1.62855284

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.86413470
2NTRK34.52997499
3MST43.88577112
4MAP3K93.87689647
5DAPK22.94233500
6RIPK42.83400777
7KSR22.58862359
8PBK2.58311138
9MAP3K42.56956687
10ACVR1B2.49886733
11PRKD32.48887522
12MINK12.47977734
13TSSK62.40891303
14PAK62.10651599
15CAMKK12.09057352
16MAP2K72.04905135
17BUB11.97112535
18ARAF1.88849566
19NTRK11.87106292
20MAP3K121.82321072
21MARK11.81976324
22DAPK11.81776704
23MAP3K131.75201495
24NTRK21.72852699
25TTK1.69575571
26MAP2K41.69379144
27KSR11.64276694
28CDK51.59076724
29FES1.52847445
30SIK21.48520001
31PRPF4B1.47393746
32GRK51.37992047
33MAP3K21.36378695
34TNIK1.34869874
35STK381.34759735
36PLK21.29327718
37CDK191.23232163
38TYRO31.23161609
39PRKCG1.17427874
40CAMKK21.17099961
41TAOK11.16040911
42RAF11.15667334
43PTK2B1.15004949
44BMPR21.14350958
45CDC71.13385707
46CASK1.12606057
47PNCK1.11823574
48PLK31.09524973
49CAMK11.00645422
50BMX1.00470600
51SRPK10.99822030
52CAMK2A0.94870225
53UHMK10.92374855
54PINK10.91973334
55PRKCH0.89341474
56TRIM280.88415767
57SGK2230.87287930
58SGK4940.87287930
59STK110.87219013
60MAPK130.86519557
61SCYL20.84823747
62CDK180.84551238
63CAMK2B0.83936917
64CDK150.83655546
65PLK10.82085393
66CDK140.81602515
67PDK10.80626460
68RET0.79097945
69PDPK10.77872707
70PRKCI0.77238116
71ALK0.76407720
72MAP3K10.75704699
73SGK10.74432412
74SGK20.73203072
75CDK11A0.72529417
76TNK20.71181392
77STK160.69207724
78SGK30.68009901
79PKN10.67341412
80PRKG20.67175939
81MARK20.65778383
82OXSR10.64182027
83CSNK1E0.62804196
84NME10.58722886
85PDK20.58115258
86LMTK20.57828134
87FGR0.57659408
88PAK30.56065701
89DAPK30.54845184
90NEK60.54057883
91DYRK1A0.52029975
92RIPK10.51054941
93NEK10.50804536
94LATS20.50656213
95MAP3K70.50335388
96CAMK40.48808965
97RPS6KA30.48686876
98MAP2K10.48316847
99PHKG20.48162939
100PHKG10.48162939
101PRKCZ0.47396444
102FYN0.47230667
103MAP2K60.46187232
104DMPK0.46186971
105CAMK2G0.44834927
106MAPK100.44018844
107CAMK2D0.43858578
108BRSK10.43822461
109PRKCE0.43341986
110IRAK20.42857660
111BRAF0.42368132
112MOS0.40343910
113CAMK1D0.38561855
114AURKA0.38430284
115PRKDC0.38226649
116CSNK1G20.37261785
117CDC42BPA0.36038970
118CDK20.35543038
119CDK10.35128003
120MAP3K80.34273948
121FER0.33659253
122WEE10.32777720
123WNK10.32752444
124PRKD20.31419525
125GSK3B0.30933718
126PRKCB0.30342669
127PLK40.30008077
128PRKCA0.28532334
129CAMK1G0.27672974
130CCNB10.26669609

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.53703271
2Synaptic vesicle cycle_Homo sapiens_hsa047213.11157594
3Olfactory transduction_Homo sapiens_hsa047403.06488145
4Long-term potentiation_Homo sapiens_hsa047202.85953342
5Circadian entrainment_Homo sapiens_hsa047132.77299492
6GABAergic synapse_Homo sapiens_hsa047272.66046928
7Glutamatergic synapse_Homo sapiens_hsa047242.65963045
8Amphetamine addiction_Homo sapiens_hsa050312.65574626
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.64192178
10Vitamin B6 metabolism_Homo sapiens_hsa007502.63206902
11Morphine addiction_Homo sapiens_hsa050322.62543750
12Salivary secretion_Homo sapiens_hsa049702.26635377
13Dopaminergic synapse_Homo sapiens_hsa047282.21729870
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.14128701
15Folate biosynthesis_Homo sapiens_hsa007902.05375544
16Gastric acid secretion_Homo sapiens_hsa049711.97890603
17Cholinergic synapse_Homo sapiens_hsa047251.97687813
18Insulin secretion_Homo sapiens_hsa049111.96919508
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.92872712
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.85255327
21Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.83362921
22Cocaine addiction_Homo sapiens_hsa050301.80560517
23Renin secretion_Homo sapiens_hsa049241.80522629
24Oxytocin signaling pathway_Homo sapiens_hsa049211.76569131
25Long-term depression_Homo sapiens_hsa047301.72343678
26Calcium signaling pathway_Homo sapiens_hsa040201.71225394
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.69604453
28Taste transduction_Homo sapiens_hsa047421.69557550
29Mismatch repair_Homo sapiens_hsa034301.67829131
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.65986143
31Serotonergic synapse_Homo sapiens_hsa047261.60765134
32GnRH signaling pathway_Homo sapiens_hsa049121.53078713
33Non-homologous end-joining_Homo sapiens_hsa034501.53056387
34Proteasome_Homo sapiens_hsa030501.46026686
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.45017150
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.41881501
37Gap junction_Homo sapiens_hsa045401.40851097
38Nitrogen metabolism_Homo sapiens_hsa009101.38150989
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.35487492
40Collecting duct acid secretion_Homo sapiens_hsa049661.34219512
41cAMP signaling pathway_Homo sapiens_hsa040241.33019139
42DNA replication_Homo sapiens_hsa030301.29123570
43RNA transport_Homo sapiens_hsa030131.28841537
44RNA polymerase_Homo sapiens_hsa030201.27583602
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.23983994
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23951995
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.21902170
48Glioma_Homo sapiens_hsa052141.20497341
49Homologous recombination_Homo sapiens_hsa034401.17352870
50Oxidative phosphorylation_Homo sapiens_hsa001901.15223980
51Pyruvate metabolism_Homo sapiens_hsa006201.14687649
52Estrogen signaling pathway_Homo sapiens_hsa049151.12513937
53Regulation of autophagy_Homo sapiens_hsa041401.11522742
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.10024273
55mRNA surveillance pathway_Homo sapiens_hsa030151.08910265
56Type II diabetes mellitus_Homo sapiens_hsa049301.08571858
57Cysteine and methionine metabolism_Homo sapiens_hsa002701.08139427
58cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06248042
59Protein export_Homo sapiens_hsa030601.02718144
60Melanogenesis_Homo sapiens_hsa049161.02366121
61Vascular smooth muscle contraction_Homo sapiens_hsa042701.00683772
62ErbB signaling pathway_Homo sapiens_hsa040120.99206582
63RNA degradation_Homo sapiens_hsa030180.98006709
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97531289
65Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94629147
66Parkinsons disease_Homo sapiens_hsa050120.93150699
67Axon guidance_Homo sapiens_hsa043600.91546536
68Maturity onset diabetes of the young_Homo sapiens_hsa049500.90664122
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.90637066
70Pancreatic secretion_Homo sapiens_hsa049720.89543536
71Cardiac muscle contraction_Homo sapiens_hsa042600.89068278
72Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88163404
73Oocyte meiosis_Homo sapiens_hsa041140.87217179
74Fatty acid elongation_Homo sapiens_hsa000620.86263757
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.84251693
76Dorso-ventral axis formation_Homo sapiens_hsa043200.83292749
77Thyroid hormone synthesis_Homo sapiens_hsa049180.80331757
78Vibrio cholerae infection_Homo sapiens_hsa051100.79895011
79Basal transcription factors_Homo sapiens_hsa030220.77826449
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77733812
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76854949
82Propanoate metabolism_Homo sapiens_hsa006400.76850953
83VEGF signaling pathway_Homo sapiens_hsa043700.76369942
84Choline metabolism in cancer_Homo sapiens_hsa052310.75492035
85Phototransduction_Homo sapiens_hsa047440.73839625
86Dilated cardiomyopathy_Homo sapiens_hsa054140.71626560
87Carbon metabolism_Homo sapiens_hsa012000.70207563
88MAPK signaling pathway_Homo sapiens_hsa040100.68727654
89Purine metabolism_Homo sapiens_hsa002300.67347555
90Huntingtons disease_Homo sapiens_hsa050160.65883330
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65195345
92Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64751754
93Arginine and proline metabolism_Homo sapiens_hsa003300.64134887
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.64055437
95Rap1 signaling pathway_Homo sapiens_hsa040150.64054946
96Neurotrophin signaling pathway_Homo sapiens_hsa047220.61089190
97Type I diabetes mellitus_Homo sapiens_hsa049400.57854625
98Spliceosome_Homo sapiens_hsa030400.57830333
99Non-small cell lung cancer_Homo sapiens_hsa052230.57179327
100Cell cycle_Homo sapiens_hsa041100.57090376
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56251194
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.56131525
103Ras signaling pathway_Homo sapiens_hsa040140.55799278
104Glucagon signaling pathway_Homo sapiens_hsa049220.54966644
105Biosynthesis of amino acids_Homo sapiens_hsa012300.54850616
106African trypanosomiasis_Homo sapiens_hsa051430.53815518
107Alcoholism_Homo sapiens_hsa050340.52998124
108Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52101706
109Base excision repair_Homo sapiens_hsa034100.51691865
110Bile secretion_Homo sapiens_hsa049760.50997226
111mTOR signaling pathway_Homo sapiens_hsa041500.50931312
112Inositol phosphate metabolism_Homo sapiens_hsa005620.50553175
113Endocytosis_Homo sapiens_hsa041440.49603671
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.46997289
115Prion diseases_Homo sapiens_hsa050200.44578444
116Chemokine signaling pathway_Homo sapiens_hsa040620.42539624
117Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38897697
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38525009
119Circadian rhythm_Homo sapiens_hsa047100.37929467
120Tight junction_Homo sapiens_hsa045300.37514536
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37438650
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.36964031
123Nucleotide excision repair_Homo sapiens_hsa034200.36925344
124Renal cell carcinoma_Homo sapiens_hsa052110.35486461
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.34438549
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34143188
127Arginine biosynthesis_Homo sapiens_hsa002200.32938000
128Endometrial cancer_Homo sapiens_hsa052130.32618888
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32554087
130Insulin signaling pathway_Homo sapiens_hsa049100.32458042
131Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.32232121
132Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.32081035
133Ovarian steroidogenesis_Homo sapiens_hsa049130.31990780
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31886818
135Wnt signaling pathway_Homo sapiens_hsa043100.31876861
136Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.31657197
137One carbon pool by folate_Homo sapiens_hsa006700.31569869
138Platelet activation_Homo sapiens_hsa046110.28616016
139Alzheimers disease_Homo sapiens_hsa050100.28450082
140Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.26596143
141Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.26457229

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