Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.77548221 |
2 | L-amino acid import (GO:0043092) | 5.90406846 |
3 | synaptic vesicle maturation (GO:0016188) | 5.72881235 |
4 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.56666807 |
5 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 5.52373551 |
6 | synaptic vesicle exocytosis (GO:0016079) | 5.49147486 |
7 | glutamate secretion (GO:0014047) | 5.40897721 |
8 | central nervous system myelination (GO:0022010) | 5.40613801 |
9 | axon ensheathment in central nervous system (GO:0032291) | 5.40613801 |
10 | regulation of neuronal synaptic plasticity (GO:0048168) | 5.25961354 |
11 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.21142243 |
12 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.16498445 |
13 | amino acid import (GO:0043090) | 5.13825035 |
14 | vocalization behavior (GO:0071625) | 5.04941525 |
15 | glutamate receptor signaling pathway (GO:0007215) | 5.01275406 |
16 | protein localization to synapse (GO:0035418) | 4.88140203 |
17 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.85365702 |
18 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.85102470 |
19 | exploration behavior (GO:0035640) | 4.83006315 |
20 | neuronal action potential propagation (GO:0019227) | 4.78318656 |
21 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.77109111 |
22 | positive regulation of synapse maturation (GO:0090129) | 4.75910278 |
23 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.75113128 |
24 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.74939307 |
25 | locomotory exploration behavior (GO:0035641) | 4.61996174 |
26 | regulation of synaptic vesicle transport (GO:1902803) | 4.51312562 |
27 | long-term synaptic potentiation (GO:0060291) | 4.48613307 |
28 | synaptic transmission, glutamatergic (GO:0035249) | 4.47289509 |
29 | regulation of synaptic plasticity (GO:0048167) | 4.38664570 |
30 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 4.27640713 |
31 | potassium ion homeostasis (GO:0055075) | 4.22076674 |
32 | neuron-neuron synaptic transmission (GO:0007270) | 4.21899561 |
33 | potassium ion import (GO:0010107) | 4.20901142 |
34 | long-term memory (GO:0007616) | 4.18904907 |
35 | behavioral defense response (GO:0002209) | 4.18630136 |
36 | behavioral fear response (GO:0001662) | 4.18630136 |
37 | regulation of dendritic spine morphogenesis (GO:0061001) | 4.15635561 |
38 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.07922186 |
39 | regulation of postsynaptic membrane potential (GO:0060078) | 4.01069766 |
40 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 4.00115447 |
41 | neuron cell-cell adhesion (GO:0007158) | 3.97838856 |
42 | neurotransmitter uptake (GO:0001504) | 3.92870388 |
43 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.91268118 |
44 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 3.89615478 |
45 | fear response (GO:0042596) | 3.88438206 |
46 | cellular potassium ion homeostasis (GO:0030007) | 3.86182893 |
47 | acidic amino acid transport (GO:0015800) | 3.74915466 |
48 | neuronal ion channel clustering (GO:0045161) | 3.73875528 |
49 | neuron recognition (GO:0008038) | 3.72352887 |
50 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.70907055 |
51 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.70608232 |
52 | regulation of vesicle fusion (GO:0031338) | 3.70240197 |
53 | positive regulation of membrane potential (GO:0045838) | 3.69243553 |
54 | regulation of synapse structural plasticity (GO:0051823) | 3.62104582 |
55 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.61302468 |
56 | neurotransmitter secretion (GO:0007269) | 3.61153595 |
57 | synaptic vesicle endocytosis (GO:0048488) | 3.59327626 |
58 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.58762784 |
59 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.58488803 |
60 | regulation of synapse maturation (GO:0090128) | 3.56197830 |
61 | gonadal mesoderm development (GO:0007506) | 3.55497865 |
62 | regulation of neurotransmitter levels (GO:0001505) | 3.54754727 |
63 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.52346703 |
64 | response to histamine (GO:0034776) | 3.51822252 |
65 | regulation of dendritic spine development (GO:0060998) | 3.51104500 |
66 | adenosine receptor signaling pathway (GO:0001973) | 3.50321881 |
67 | cell communication by electrical coupling (GO:0010644) | 3.50301935 |
68 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.50132484 |
69 | dendritic spine organization (GO:0097061) | 3.43027252 |
70 | neuromuscular process controlling posture (GO:0050884) | 3.40508238 |
71 | innervation (GO:0060384) | 3.40498660 |
72 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.38389511 |
73 | L-glutamate transport (GO:0015813) | 3.37700262 |
74 | dendritic spine morphogenesis (GO:0060997) | 3.37280147 |
75 | neuromuscular synaptic transmission (GO:0007274) | 3.36716218 |
76 | cerebellar granule cell differentiation (GO:0021707) | 3.34784794 |
77 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.32937958 |
78 | regulation of neurotransmitter secretion (GO:0046928) | 3.29686514 |
79 | presynaptic membrane organization (GO:0097090) | 3.29121951 |
80 | regulation of neurotransmitter uptake (GO:0051580) | 3.28198944 |
81 | regulation of synaptic transmission (GO:0050804) | 3.27145841 |
82 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.27030695 |
83 | regulation of sensory perception of pain (GO:0051930) | 3.26967768 |
84 | regulation of sensory perception (GO:0051931) | 3.26967768 |
85 | axonal fasciculation (GO:0007413) | 3.24681192 |
86 | long term synaptic depression (GO:0060292) | 3.24534994 |
87 | detection of calcium ion (GO:0005513) | 3.24329346 |
88 | regulation of glutamate secretion (GO:0014048) | 3.24077623 |
89 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.23707791 |
90 | chemosensory behavior (GO:0007635) | 3.20971088 |
91 | vesicle transport along microtubule (GO:0047496) | 3.20065809 |
92 | positive regulation of dendritic spine development (GO:0060999) | 3.19375828 |
93 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.19173456 |
94 | serotonin metabolic process (GO:0042428) | 3.19123476 |
95 | response to gravity (GO:0009629) | 3.17950916 |
96 | membrane depolarization (GO:0051899) | 3.17445944 |
97 | positive regulation of fibroblast migration (GO:0010763) | 3.12663975 |
98 | sodium ion export (GO:0071436) | 3.12228872 |
99 | cellular sodium ion homeostasis (GO:0006883) | 3.12003352 |
100 | positive regulation of vesicle fusion (GO:0031340) | 3.10978077 |
101 | presynaptic membrane assembly (GO:0097105) | 3.10593932 |
102 | proline transport (GO:0015824) | 3.09334302 |
103 | positive regulation of neurotransmitter transport (GO:0051590) | 3.07926796 |
104 | cochlea development (GO:0090102) | 3.07808778 |
105 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.07050564 |
106 | positive regulation of synaptic transmission (GO:0050806) | 3.06742689 |
107 | auditory behavior (GO:0031223) | 3.06385365 |
108 | ephrin receptor signaling pathway (GO:0048013) | 3.03847116 |
109 | gamma-aminobutyric acid transport (GO:0015812) | 3.03465879 |
110 | adult walking behavior (GO:0007628) | 3.01920585 |
111 | signal complex assembly (GO:0007172) | 3.01627160 |
112 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.00040373 |
113 | response to auditory stimulus (GO:0010996) | 2.99186218 |
114 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.98198448 |
115 | regulation of respiratory gaseous exchange (GO:0043576) | 2.98185154 |
116 | synaptic transmission (GO:0007268) | 2.97778763 |
117 | chondroitin sulfate catabolic process (GO:0030207) | 2.97020835 |
118 | regulation of neurotransmitter transport (GO:0051588) | 2.96319391 |
119 | learning (GO:0007612) | 2.96315870 |
120 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.95837170 |
121 | neuromuscular process controlling balance (GO:0050885) | 2.95792591 |
122 | postsynaptic membrane organization (GO:0001941) | 2.94795235 |
123 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.94451905 |
124 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.94451905 |
125 | response to dietary excess (GO:0002021) | 2.94059415 |
126 | neurotransmitter transport (GO:0006836) | 2.93931405 |
127 | negative regulation of dendrite development (GO:2000171) | 2.93121492 |
128 | cerebellar Purkinje cell layer development (GO:0021680) | 2.92939334 |
129 | regulation of respiratory system process (GO:0044065) | 2.92279671 |
130 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 2.89967928 |
131 | negative regulation of amino acid transport (GO:0051956) | 2.89833637 |
132 | transferrin transport (GO:0033572) | 2.89800132 |
133 | transmission of nerve impulse (GO:0019226) | 2.87292141 |
134 | regulation of circadian sleep/wake cycle (GO:0042749) | 2.87260162 |
135 | regulation of circadian sleep/wake cycle, sleep (GO:0045187) | 2.87260162 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.82863276 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.49255253 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.40831611 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.34211996 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.29732206 |
6 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 3.04240799 |
7 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.97253100 |
8 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.95156847 |
9 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.95156847 |
10 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.88036725 |
11 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.83318671 |
12 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.82925408 |
13 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.68283034 |
14 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.65915860 |
15 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.61275124 |
16 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.60381302 |
17 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.58899780 |
18 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.57588121 |
19 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.40866064 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.36852167 |
21 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.33446667 |
22 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.32282234 |
23 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.20195182 |
24 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.13280265 |
25 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.06158168 |
26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.99313679 |
27 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.97924664 |
28 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.92543424 |
29 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.84809128 |
30 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.80747879 |
31 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.78978789 |
32 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78729562 |
33 | VDR_22108803_ChIP-Seq_LS180_Human | 1.71743277 |
34 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.69866416 |
35 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.68857796 |
36 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.59659260 |
37 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.58617780 |
38 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.57525306 |
39 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.57182062 |
40 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.52482273 |
41 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.51752528 |
42 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.50915830 |
43 | P68_20966046_ChIP-Seq_HELA_Human | 1.45304275 |
44 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.45171313 |
45 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.43774583 |
46 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.40358702 |
47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.39838714 |
48 | AR_25329375_ChIP-Seq_VCAP_Human | 1.38442750 |
49 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.36630054 |
50 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.36445207 |
51 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.35547643 |
52 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.33046150 |
53 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.32573683 |
54 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.31733355 |
55 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.31308117 |
56 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.27151961 |
57 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.27024832 |
58 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.26621999 |
59 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.25926976 |
60 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.24788215 |
61 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.24478158 |
62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.22651498 |
63 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.22369074 |
64 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21169064 |
65 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.20980466 |
66 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.20557769 |
67 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.19207728 |
68 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.18241256 |
69 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.13797281 |
70 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.12970800 |
71 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.12489146 |
72 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.12452873 |
73 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.11050279 |
74 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.07311780 |
75 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.06921586 |
76 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.06724731 |
77 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.05099680 |
78 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.03807721 |
79 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.03404435 |
80 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.03198918 |
81 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.03023943 |
82 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02830125 |
83 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.01319618 |
84 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.01195858 |
85 | AR_19668381_ChIP-Seq_PC3_Human | 1.00807438 |
86 | SA1_27219007_Chip-Seq_Bcells_Human | 0.99759100 |
87 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.99485288 |
88 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.99207296 |
89 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.99171002 |
90 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.98744351 |
91 | FUS_26573619_Chip-Seq_HEK293_Human | 0.98060765 |
92 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97953377 |
93 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.97682965 |
94 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.97582459 |
95 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97509696 |
96 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.97398074 |
97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97238243 |
98 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.96714324 |
99 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96578185 |
100 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.96474003 |
101 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.96360249 |
102 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.95385254 |
103 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.95144373 |
104 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.94941822 |
105 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.94664092 |
106 | TP53_16413492_ChIP-PET_HCT116_Human | 0.94450972 |
107 | * CTCF_20526341_ChIP-Seq_ESCs_Human | 0.94260798 |
108 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.93920543 |
109 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.93321231 |
110 | STAT3_23295773_ChIP-Seq_U87_Human | 0.93112796 |
111 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.93052859 |
112 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92148721 |
113 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.90708572 |
114 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.90100603 |
115 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.89932065 |
116 | * KDM2B_26808549_Chip-Seq_DND41_Human | 0.89823933 |
117 | JUN_21703547_ChIP-Seq_K562_Human | 0.89545396 |
118 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89196078 |
119 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.89033948 |
120 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.88508934 |
121 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.87743852 |
122 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.86838297 |
123 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.86515382 |
124 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.86000903 |
125 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.85368396 |
126 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.84946388 |
127 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.84803493 |
128 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.84794054 |
129 | KDM2B_26808549_Chip-Seq_K562_Human | 0.84138597 |
130 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.83992161 |
131 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.83477171 |
132 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.82248608 |
133 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.82234110 |
134 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.80336908 |
135 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.80303492 |
136 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.80017323 |
137 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.79272770 |
138 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.78687146 |
139 | RXR_22108803_ChIP-Seq_LS180_Human | 0.77953035 |
140 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.77737874 |
141 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.77686404 |
142 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.77613150 |
143 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.76745588 |
144 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.76272746 |
145 | ERA_21632823_ChIP-Seq_H3396_Human | 0.75788451 |
146 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.74997720 |
147 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.74729018 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 7.88772081 |
2 | MP0003880_abnormal_central_pattern | 5.79822742 |
3 | MP0003635_abnormal_synaptic_transmissio | 4.30126245 |
4 | MP0002063_abnormal_learning/memory/cond | 3.55531941 |
5 | MP0009745_abnormal_behavioral_response | 3.52315135 |
6 | MP0004270_analgesia | 3.50491605 |
7 | MP0002064_seizures | 3.22676062 |
8 | MP0002822_catalepsy | 3.21295912 |
9 | MP0002572_abnormal_emotion/affect_behav | 2.83881277 |
10 | MP0003329_amyloid_beta_deposits | 2.74159226 |
11 | MP0001968_abnormal_touch/_nociception | 2.72947202 |
12 | MP0001501_abnormal_sleep_pattern | 2.72320036 |
13 | MP0009046_muscle_twitch | 2.65803483 |
14 | MP0005167_abnormal_blood-brain_barrier | 2.64456793 |
15 | MP0003690_abnormal_glial_cell | 2.61779242 |
16 | MP0002735_abnormal_chemical_nociception | 2.50476411 |
17 | MP0002736_abnormal_nociception_after | 2.50355650 |
18 | MP0001440_abnormal_grooming_behavior | 2.47830761 |
19 | MP0002272_abnormal_nervous_system | 2.47415354 |
20 | MP0010234_abnormal_vibrissa_follicle | 2.25609593 |
21 | MP0001486_abnormal_startle_reflex | 2.10604208 |
22 | MP0002734_abnormal_mechanical_nocicepti | 2.09744675 |
23 | MP0004858_abnormal_nervous_system | 2.04985761 |
24 | MP0003787_abnormal_imprinting | 2.01756625 |
25 | MP0003879_abnormal_hair_cell | 1.98253514 |
26 | MP0003136_yellow_coat_color | 1.98213881 |
27 | MP0000920_abnormal_myelination | 1.86929377 |
28 | MP0003183_abnormal_peptide_metabolism | 1.81941655 |
29 | MP0002733_abnormal_thermal_nociception | 1.72110405 |
30 | MP0001986_abnormal_taste_sensitivity | 1.70611413 |
31 | MP0002184_abnormal_innervation | 1.69043870 |
32 | MP0002067_abnormal_sensory_capabilities | 1.66021453 |
33 | MP0001970_abnormal_pain_threshold | 1.62308315 |
34 | MP0002653_abnormal_ependyma_morphology | 1.58928151 |
35 | MP0001905_abnormal_dopamine_level | 1.53704992 |
36 | MP0004811_abnormal_neuron_physiology | 1.53167778 |
37 | MP0000778_abnormal_nervous_system | 1.52430711 |
38 | MP0002557_abnormal_social/conspecific_i | 1.50793449 |
39 | MP0005386_behavior/neurological_phenoty | 1.48077485 |
40 | MP0004924_abnormal_behavior | 1.48077485 |
41 | MP0002876_abnormal_thyroid_physiology | 1.47891402 |
42 | MP0008569_lethality_at_weaning | 1.43607912 |
43 | MP0005423_abnormal_somatic_nervous | 1.43397482 |
44 | MP0003172_abnormal_lysosome_physiology | 1.37992470 |
45 | MP0005171_absent_coat_pigmentation | 1.36242878 |
46 | MP0000751_myopathy | 1.35117684 |
47 | MP0003075_altered_response_to | 1.28677053 |
48 | MP0004510_myositis | 1.28494861 |
49 | MP0000604_amyloidosis | 1.28443630 |
50 | MP0006276_abnormal_autonomic_nervous | 1.26791159 |
51 | MP0000955_abnormal_spinal_cord | 1.25728213 |
52 | MP0002066_abnormal_motor_capabilities/c | 1.25031300 |
53 | MP0002882_abnormal_neuron_morphology | 1.20342672 |
54 | MP0009780_abnormal_chondrocyte_physiolo | 1.18305833 |
55 | MP0001346_abnormal_lacrimal_gland | 1.16872217 |
56 | MP0002909_abnormal_adrenal_gland | 1.16580910 |
57 | MP0004484_altered_response_of | 1.16469914 |
58 | MP0005646_abnormal_pituitary_gland | 1.14686480 |
59 | MP0003123_paternal_imprinting | 1.12615931 |
60 | MP0002837_dystrophic_cardiac_calcinosis | 1.12392551 |
61 | MP0003631_nervous_system_phenotype | 1.07798708 |
62 | MP0001984_abnormal_olfaction | 1.05870754 |
63 | MP0001502_abnormal_circadian_rhythm | 1.04465279 |
64 | MP0004215_abnormal_myocardial_fiber | 1.03394677 |
65 | MP0003633_abnormal_nervous_system | 1.03259037 |
66 | MP0002796_impaired_skin_barrier | 1.00659680 |
67 | MP0002638_abnormal_pupillary_reflex | 0.99848377 |
68 | MP0003632_abnormal_nervous_system | 0.96924830 |
69 | MP0001529_abnormal_vocalization | 0.96064496 |
70 | MP0004085_abnormal_heartbeat | 0.95772809 |
71 | MP0005174_abnormal_tail_pigmentation | 0.92545911 |
72 | MP0002152_abnormal_brain_morphology | 0.92174748 |
73 | MP0001188_hyperpigmentation | 0.90902722 |
74 | MP0004043_abnormal_pH_regulation | 0.88959803 |
75 | MP0008877_abnormal_DNA_methylation | 0.88024945 |
76 | MP0002069_abnormal_eating/drinking_beha | 0.87458803 |
77 | MP0005058_abnormal_lysosome_morphology | 0.87326482 |
78 | MP0008874_decreased_physiological_sensi | 0.86242267 |
79 | MP0002234_abnormal_pharynx_morphology | 0.86144951 |
80 | MP0004145_abnormal_muscle_electrophysio | 0.85897702 |
81 | MP0003303_peritoneal_inflammation | 0.84966911 |
82 | MP0005535_abnormal_body_temperature | 0.83334914 |
83 | MP0000026_abnormal_inner_ear | 0.79888265 |
84 | MP0010386_abnormal_urinary_bladder | 0.77905350 |
85 | MP0004130_abnormal_muscle_cell | 0.76436252 |
86 | MP0008872_abnormal_physiological_respon | 0.76433133 |
87 | MP0003938_abnormal_ear_development | 0.75033761 |
88 | MP0004885_abnormal_endolymph | 0.74950329 |
89 | MP0004142_abnormal_muscle_tone | 0.73137836 |
90 | MP0001765_abnormal_ion_homeostasis | 0.72357909 |
91 | MP0005379_endocrine/exocrine_gland_phen | 0.69083648 |
92 | MP0001963_abnormal_hearing_physiology | 0.68854298 |
93 | MP0010678_abnormal_skin_adnexa | 0.67829535 |
94 | MP0005670_abnormal_white_adipose | 0.67625015 |
95 | MP0002229_neurodegeneration | 0.66609813 |
96 | MP0003122_maternal_imprinting | 0.65403625 |
97 | MP0000013_abnormal_adipose_tissue | 0.64864233 |
98 | MP0001485_abnormal_pinna_reflex | 0.63793941 |
99 | MP0003941_abnormal_skin_development | 0.62055388 |
100 | MP0009840_abnormal_foam_cell | 0.59635672 |
101 | MP0001177_atelectasis | 0.56903969 |
102 | MP0003634_abnormal_glial_cell | 0.56440843 |
103 | MP0005623_abnormal_meninges_morphology | 0.55175666 |
104 | MP0000747_muscle_weakness | 0.54731910 |
105 | MP0002752_abnormal_somatic_nervous | 0.53931032 |
106 | MP0005253_abnormal_eye_physiology | 0.52694996 |
107 | MP0005595_abnormal_vascular_smooth | 0.52646725 |
108 | MP0003137_abnormal_impulse_conducting | 0.52324179 |
109 | MP0001756_abnormal_urination | 0.49764363 |
110 | MP0001664_abnormal_digestion | 0.49503250 |
111 | MP0002090_abnormal_vision | 0.49029846 |
112 | MP0004742_abnormal_vestibular_system | 0.47945046 |
113 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.47720254 |
114 | MP0005551_abnormal_eye_electrophysiolog | 0.47500900 |
115 | MP0006138_congestive_heart_failure | 0.47466320 |
116 | MP0005187_abnormal_penis_morphology | 0.45741198 |
117 | MP0006292_abnormal_olfactory_placode | 0.45173008 |
118 | MP0004036_abnormal_muscle_relaxation | 0.44530838 |
119 | MP0005620_abnormal_muscle_contractility | 0.44289286 |
120 | MP0003861_abnormal_nervous_system | 0.43981731 |
121 | MP0005166_decreased_susceptibility_to | 0.43938089 |
122 | MP0006035_abnormal_mitochondrial_morpho | 0.42970226 |
123 | MP0005645_abnormal_hypothalamus_physiol | 0.40807933 |
124 | MP0001348_abnormal_lacrimal_gland | 0.39028089 |
125 | MP0003956_abnormal_body_size | 0.38115528 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 8.21383743 |
2 | Myokymia (HP:0002411) | 6.76785584 |
3 | Focal seizures (HP:0007359) | 6.18571472 |
4 | Visual hallucinations (HP:0002367) | 5.98804237 |
5 | Epileptic encephalopathy (HP:0200134) | 4.98279721 |
6 | Atonic seizures (HP:0010819) | 4.75560107 |
7 | Absence seizures (HP:0002121) | 4.46749406 |
8 | Dialeptic seizures (HP:0011146) | 4.27679380 |
9 | Febrile seizures (HP:0002373) | 4.21684297 |
10 | Generalized tonic-clonic seizures (HP:0002069) | 3.96469636 |
11 | Abnormality of the lower motor neuron (HP:0002366) | 3.78045315 |
12 | Amblyopia (HP:0000646) | 3.74927269 |
13 | Akinesia (HP:0002304) | 3.59091252 |
14 | Progressive cerebellar ataxia (HP:0002073) | 3.58317651 |
15 | Delusions (HP:0000746) | 3.52433073 |
16 | Abnormal drinking behavior (HP:0030082) | 3.40634602 |
17 | Polydipsia (HP:0001959) | 3.40634602 |
18 | Peripheral hypomyelination (HP:0007182) | 3.36805308 |
19 | Hemiplegia (HP:0002301) | 3.35553464 |
20 | Gaze-evoked nystagmus (HP:0000640) | 3.29708385 |
21 | Progressive inability to walk (HP:0002505) | 3.25360334 |
22 | Cerebral inclusion bodies (HP:0100314) | 3.21932186 |
23 | Hyperventilation (HP:0002883) | 3.17303607 |
24 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.13192863 |
25 | Neuronal loss in central nervous system (HP:0002529) | 3.06827263 |
26 | Supranuclear gaze palsy (HP:0000605) | 3.04845209 |
27 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 3.04032702 |
28 | Action tremor (HP:0002345) | 3.03125380 |
29 | Abnormality of glycolipid metabolism (HP:0010969) | 3.02721985 |
30 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.02721985 |
31 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.02721985 |
32 | Tetraplegia (HP:0002445) | 2.99350349 |
33 | Ventricular fibrillation (HP:0001663) | 2.97891054 |
34 | Dysmetria (HP:0001310) | 2.96219770 |
35 | Stereotypic behavior (HP:0000733) | 2.95544396 |
36 | Broad-based gait (HP:0002136) | 2.95541921 |
37 | Anomalous pulmonary venous return (HP:0010772) | 2.92772577 |
38 | Annular pancreas (HP:0001734) | 2.92234621 |
39 | Limb dystonia (HP:0002451) | 2.86223519 |
40 | Anxiety (HP:0000739) | 2.81279172 |
41 | Dysdiadochokinesis (HP:0002075) | 2.81069613 |
42 | Depression (HP:0000716) | 2.79712315 |
43 | Cerebral hypomyelination (HP:0006808) | 2.76433136 |
44 | Excessive salivation (HP:0003781) | 2.73156665 |
45 | Drooling (HP:0002307) | 2.73156665 |
46 | Poor eye contact (HP:0000817) | 2.72747881 |
47 | Inability to walk (HP:0002540) | 2.71353519 |
48 | Truncal ataxia (HP:0002078) | 2.67743907 |
49 | Ankle clonus (HP:0011448) | 2.67693668 |
50 | Epileptiform EEG discharges (HP:0011182) | 2.67287037 |
51 | Thickened helices (HP:0000391) | 2.62499237 |
52 | Mutism (HP:0002300) | 2.60374424 |
53 | Abnormal eating behavior (HP:0100738) | 2.60184894 |
54 | Polyphagia (HP:0002591) | 2.56646994 |
55 | Abnormality of the pulmonary veins (HP:0011718) | 2.52586586 |
56 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.51343600 |
57 | Impaired social interactions (HP:0000735) | 2.50644556 |
58 | Abnormal social behavior (HP:0012433) | 2.50644556 |
59 | Increased cerebral lipofuscin (HP:0011813) | 2.42568106 |
60 | Bundle branch block (HP:0011710) | 2.41621751 |
61 | Hypomagnesemia (HP:0002917) | 2.40396393 |
62 | EEG with generalized epileptiform discharges (HP:0011198) | 2.38116188 |
63 | Impaired smooth pursuit (HP:0007772) | 2.37171300 |
64 | Dysmetric saccades (HP:0000641) | 2.36794304 |
65 | Rapidly progressive (HP:0003678) | 2.35276213 |
66 | Abnormality of magnesium homeostasis (HP:0004921) | 2.34430599 |
67 | Neurofibrillary tangles (HP:0002185) | 2.33159473 |
68 | Rigidity (HP:0002063) | 2.32814985 |
69 | Insomnia (HP:0100785) | 2.32195195 |
70 | Dementia (HP:0000726) | 2.31073448 |
71 | Global brain atrophy (HP:0002283) | 2.29826057 |
72 | Urinary urgency (HP:0000012) | 2.28888673 |
73 | Postural instability (HP:0002172) | 2.27725329 |
74 | Megalencephaly (HP:0001355) | 2.27530281 |
75 | Papilledema (HP:0001085) | 2.25962680 |
76 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.24429389 |
77 | Split foot (HP:0001839) | 2.23814826 |
78 | Heart block (HP:0012722) | 2.21778678 |
79 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.20976063 |
80 | Diminished movement (HP:0002374) | 2.20634125 |
81 | Fetal akinesia sequence (HP:0001989) | 2.19603112 |
82 | Insidious onset (HP:0003587) | 2.19090671 |
83 | Termporal pattern (HP:0011008) | 2.19090671 |
84 | Genetic anticipation (HP:0003743) | 2.18492139 |
85 | Decreased circulating renin level (HP:0003351) | 2.17742984 |
86 | Hypsarrhythmia (HP:0002521) | 2.16465853 |
87 | Syncope (HP:0001279) | 2.16429437 |
88 | Spastic tetraparesis (HP:0001285) | 2.15523381 |
89 | Abnormality of binocular vision (HP:0011514) | 2.15216361 |
90 | Diplopia (HP:0000651) | 2.15216361 |
91 | Deep palmar crease (HP:0006191) | 2.15160372 |
92 | Rib fusion (HP:0000902) | 2.13001169 |
93 | Absent speech (HP:0001344) | 2.12892023 |
94 | Torticollis (HP:0000473) | 2.11081734 |
95 | Incomplete penetrance (HP:0003829) | 2.10795700 |
96 | Shoulder girdle muscle weakness (HP:0003547) | 2.10792732 |
97 | Polyuria (HP:0000103) | 2.10176611 |
98 | Generalized myoclonic seizures (HP:0002123) | 2.09402009 |
99 | Impaired vibratory sensation (HP:0002495) | 2.07865594 |
100 | Obstructive sleep apnea (HP:0002870) | 2.06396231 |
101 | Bradykinesia (HP:0002067) | 2.05404396 |
102 | Unsteady gait (HP:0002317) | 2.05290572 |
103 | Hyperactive renin-angiotensin system (HP:0000841) | 2.03882679 |
104 | Clonus (HP:0002169) | 2.03818842 |
105 | Increased circulating renin level (HP:0000848) | 2.03387418 |
106 | Disinhibition (HP:0000734) | 2.02405332 |
107 | Sudden death (HP:0001699) | 2.02357583 |
108 | Axonal loss (HP:0003447) | 2.02093491 |
109 | Turricephaly (HP:0000262) | 2.01333484 |
110 | Focal dystonia (HP:0004373) | 2.00421431 |
111 | Abnormality of cochlea (HP:0000375) | 1.99043356 |
112 | Morphological abnormality of the inner ear (HP:0011390) | 1.98970893 |
113 | Difficulty climbing stairs (HP:0003551) | 1.98579833 |
114 | Mesangial abnormality (HP:0001966) | 1.97747199 |
115 | Atrioventricular block (HP:0001678) | 1.97104927 |
116 | Oligodactyly (hands) (HP:0001180) | 1.96911435 |
117 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.96868760 |
118 | Intention tremor (HP:0002080) | 1.96785656 |
119 | Memory impairment (HP:0002354) | 1.96242059 |
120 | Truncus arteriosus (HP:0001660) | 1.95603830 |
121 | Choreoathetosis (HP:0001266) | 1.95491009 |
122 | Apathy (HP:0000741) | 1.95249131 |
123 | Abnormal atrioventricular conduction (HP:0005150) | 1.94564684 |
124 | Dysautonomia (HP:0002459) | 1.92960840 |
125 | Abnormality of the periventricular white matter (HP:0002518) | 1.91056506 |
126 | Inappropriate behavior (HP:0000719) | 1.90943003 |
127 | Abnormal urine output (HP:0012590) | 1.90445281 |
128 | Abnormality of salivation (HP:0100755) | 1.87982248 |
129 | CNS hypomyelination (HP:0003429) | 1.84445576 |
130 | Lower limb asymmetry (HP:0100559) | 1.83442908 |
131 | Achilles tendon contracture (HP:0001771) | 1.83358006 |
132 | Status epilepticus (HP:0002133) | 1.82622172 |
133 | Spastic gait (HP:0002064) | 1.80380212 |
134 | Confusion (HP:0001289) | 1.79866949 |
135 | Hemiparesis (HP:0001269) | 1.79311567 |
136 | Childhood onset (HP:0011463) | 1.78201146 |
137 | Testicular atrophy (HP:0000029) | 1.74487773 |
138 | Scanning speech (HP:0002168) | 1.71724360 |
139 | Congenital malformation of the right heart (HP:0011723) | 1.70503784 |
140 | Double outlet right ventricle (HP:0001719) | 1.70503784 |
141 | Diminished motivation (HP:0000745) | 1.70068316 |
142 | Abnormality of the corticospinal tract (HP:0002492) | 1.67558846 |
143 | Gait ataxia (HP:0002066) | 1.66340439 |
144 | Lower limb amyotrophy (HP:0007210) | 1.64192901 |
145 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.63188779 |
146 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.63188779 |
147 | Craniofacial dystonia (HP:0012179) | 1.62487562 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 5.98509361 |
2 | NTRK3 | 5.01140522 |
3 | MAP3K9 | 4.93196093 |
4 | ARAF | 3.80182143 |
5 | MAP3K13 | 3.09757102 |
6 | KSR2 | 2.97260749 |
7 | RIPK4 | 2.95845841 |
8 | KSR1 | 2.34765320 |
9 | MAP3K12 | 2.30422321 |
10 | MINK1 | 2.18339066 |
11 | DAPK2 | 2.16001400 |
12 | PLK2 | 2.12023072 |
13 | PTK2B | 1.99566055 |
14 | TNK2 | 1.94352228 |
15 | PAK6 | 1.87208026 |
16 | MAP3K4 | 1.82835549 |
17 | PHKG2 | 1.77234190 |
18 | PHKG1 | 1.77234190 |
19 | NME1 | 1.70458244 |
20 | RAF1 | 1.70449537 |
21 | GRK5 | 1.67368966 |
22 | DAPK1 | 1.61356112 |
23 | MAP2K7 | 1.55912154 |
24 | BRAF | 1.53489758 |
25 | PRPF4B | 1.53181090 |
26 | PKN1 | 1.50096631 |
27 | PNCK | 1.49425882 |
28 | BMPR2 | 1.47267389 |
29 | CASK | 1.39228718 |
30 | MAP2K4 | 1.32733555 |
31 | PRKD3 | 1.30670097 |
32 | CDK5 | 1.27158495 |
33 | NEK6 | 1.26019009 |
34 | PRKCG | 1.23531797 |
35 | NTRK2 | 1.20532862 |
36 | MARK1 | 1.14866950 |
37 | MAP3K2 | 1.08279996 |
38 | FES | 1.07485022 |
39 | CAMK2B | 1.06914437 |
40 | MAP3K1 | 1.03283611 |
41 | MAP3K11 | 1.03033486 |
42 | CAMK2A | 1.02957109 |
43 | CAMKK1 | 1.01205859 |
44 | CAMK1 | 1.00851134 |
45 | FER | 1.00824698 |
46 | MAPK15 | 0.99142703 |
47 | MOS | 0.99100633 |
48 | NTRK1 | 0.98499460 |
49 | CDK19 | 0.96553670 |
50 | DYRK1A | 0.96354106 |
51 | LATS2 | 0.91258286 |
52 | RIPK1 | 0.90464340 |
53 | PINK1 | 0.89363510 |
54 | TNIK | 0.89155867 |
55 | STK38 | 0.86245145 |
56 | MAP2K1 | 0.85128323 |
57 | FGR | 0.82558964 |
58 | AKT3 | 0.82104819 |
59 | PAK3 | 0.78261277 |
60 | MAP2K6 | 0.75823426 |
61 | MAPK13 | 0.75193262 |
62 | CDK18 | 0.75168062 |
63 | IRAK2 | 0.73953306 |
64 | SIK2 | 0.73757657 |
65 | CDK14 | 0.73550485 |
66 | CDK15 | 0.70054408 |
67 | PDPK1 | 0.67411284 |
68 | ADRBK2 | 0.61830598 |
69 | PDK1 | 0.61213363 |
70 | GRK6 | 0.61023646 |
71 | SGK3 | 0.60567119 |
72 | CDK11A | 0.59871945 |
73 | TRIM28 | 0.59745551 |
74 | BCR | 0.58567892 |
75 | CAMKK2 | 0.58158203 |
76 | ROCK1 | 0.54080549 |
77 | MUSK | 0.53961824 |
78 | SIK3 | 0.53915929 |
79 | PRKCE | 0.51319936 |
80 | SGK1 | 0.51010801 |
81 | LIMK1 | 0.50922389 |
82 | UHMK1 | 0.50914226 |
83 | ROCK2 | 0.49326193 |
84 | CAMK2D | 0.47427448 |
85 | WNK4 | 0.47084946 |
86 | SGK494 | 0.45970016 |
87 | SGK223 | 0.45970016 |
88 | CAMK1D | 0.44899827 |
89 | CAMK2G | 0.44189853 |
90 | GRK7 | 0.44004140 |
91 | DAPK3 | 0.42985064 |
92 | ABL2 | 0.41655364 |
93 | BMX | 0.41535187 |
94 | STK11 | 0.41232245 |
95 | CSNK1A1L | 0.40446943 |
96 | MAP3K7 | 0.40248185 |
97 | CSNK1G3 | 0.39854157 |
98 | OXSR1 | 0.39487112 |
99 | BRSK1 | 0.39472423 |
100 | NEK1 | 0.39200548 |
101 | PRKG2 | 0.38811592 |
102 | DMPK | 0.37820569 |
103 | CSNK1A1 | 0.37282302 |
104 | TYRO3 | 0.36973314 |
105 | PDK2 | 0.36875330 |
106 | PLK3 | 0.36817951 |
107 | CDK3 | 0.34059001 |
108 | LMTK2 | 0.34057215 |
109 | PRKCH | 0.33500277 |
110 | MAPK12 | 0.33386207 |
111 | CSNK1D | 0.32192225 |
112 | PRKCZ | 0.31393005 |
113 | CCNB1 | 0.30382409 |
114 | SGK2 | 0.30041525 |
115 | PRKG1 | 0.29843544 |
116 | MAPK7 | 0.28781363 |
117 | CSNK1E | 0.28370996 |
118 | TAOK1 | 0.28225036 |
119 | PRKCA | 0.27898034 |
120 | RPS6KA3 | 0.27638822 |
121 | ERBB3 | 0.26161001 |
122 | MARK2 | 0.25792264 |
123 | CSNK1G2 | 0.24734838 |
124 | CAMK4 | 0.23540313 |
125 | PRKCI | 0.23110707 |
126 | EPHA2 | 0.22293713 |
127 | MAPK10 | 0.22231709 |
128 | PRKACA | 0.21539800 |
129 | ALK | 0.21109697 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.92686187 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.36297200 |
3 | Long-term potentiation_Homo sapiens_hsa04720 | 3.30940500 |
4 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.94755955 |
5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.89314673 |
6 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.82788979 |
7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.72348119 |
8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.50624455 |
9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.46413790 |
10 | Salivary secretion_Homo sapiens_hsa04970 | 2.34295400 |
11 | GABAergic synapse_Homo sapiens_hsa04727 | 2.29181612 |
12 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.20720369 |
13 | Morphine addiction_Homo sapiens_hsa05032 | 2.15112135 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.09401108 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.98028146 |
16 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.92736199 |
17 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.89285097 |
18 | Taste transduction_Homo sapiens_hsa04742 | 1.86669538 |
19 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.85684809 |
20 | Insulin secretion_Homo sapiens_hsa04911 | 1.84712806 |
21 | Renin secretion_Homo sapiens_hsa04924 | 1.78582872 |
22 | Long-term depression_Homo sapiens_hsa04730 | 1.78249796 |
23 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.70724896 |
24 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.70209507 |
25 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.70166672 |
26 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.66336225 |
27 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.56164028 |
28 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.55001273 |
29 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.38152431 |
30 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.32539243 |
31 | Cocaine addiction_Homo sapiens_hsa05030 | 1.27973066 |
32 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.27405380 |
33 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.21783918 |
34 | Gap junction_Homo sapiens_hsa04540 | 1.19693719 |
35 | Glioma_Homo sapiens_hsa05214 | 1.18837900 |
36 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.18545246 |
37 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.18438788 |
38 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.18017694 |
39 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.17823785 |
40 | Melanogenesis_Homo sapiens_hsa04916 | 1.16744054 |
41 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.13356444 |
42 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.12122048 |
43 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.10774819 |
44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06539270 |
45 | Axon guidance_Homo sapiens_hsa04360 | 1.05875556 |
46 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.04815421 |
47 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.04541381 |
48 | Alzheimers disease_Homo sapiens_hsa05010 | 1.02204847 |
49 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.01599563 |
50 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.00121113 |
51 | Phototransduction_Homo sapiens_hsa04744 | 0.96315030 |
52 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.95124569 |
53 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.93596741 |
54 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.93478179 |
55 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.90188373 |
56 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.89625625 |
57 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.87128533 |
58 | Lysosome_Homo sapiens_hsa04142 | 0.86508908 |
59 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.81286806 |
60 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.76776561 |
61 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.75101505 |
62 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.72247974 |
63 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.71797300 |
64 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.67839360 |
65 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.67625606 |
66 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.66337708 |
67 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.65418654 |
68 | Histidine metabolism_Homo sapiens_hsa00340 | 0.63764789 |
69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.61424487 |
70 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.61201756 |
71 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.58120494 |
72 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56245289 |
73 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.56104687 |
74 | Huntingtons disease_Homo sapiens_hsa05016 | 0.55612831 |
75 | Parkinsons disease_Homo sapiens_hsa05012 | 0.55472370 |
76 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.55032332 |
77 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.53788791 |
78 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.53367743 |
79 | Prion diseases_Homo sapiens_hsa05020 | 0.53254558 |
80 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.52354218 |
81 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52215733 |
82 | Other glycan degradation_Homo sapiens_hsa00511 | 0.51729994 |
83 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.51248970 |
84 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.50503103 |
85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50087017 |
86 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.48322217 |
87 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.46877136 |
88 | Sulfur relay system_Homo sapiens_hsa04122 | 0.46656961 |
89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.46347675 |
90 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.45961891 |
91 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.45334738 |
92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.43272411 |
93 | Circadian rhythm_Homo sapiens_hsa04710 | 0.43031855 |
94 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.42824681 |
95 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.42675767 |
96 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.41232466 |
97 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.37154434 |
98 | Salmonella infection_Homo sapiens_hsa05132 | 0.37150666 |
99 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.34987291 |
100 | Mineral absorption_Homo sapiens_hsa04978 | 0.34875761 |
101 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.34456680 |
102 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.32810695 |
103 | Alcoholism_Homo sapiens_hsa05034 | 0.32386383 |
104 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.31209165 |
105 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.30935559 |
106 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.30318977 |
107 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.29388380 |
108 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.29172239 |
109 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.28887408 |
110 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.28758498 |
111 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.27840306 |
112 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.27293107 |
113 | Endocytosis_Homo sapiens_hsa04144 | 0.26899899 |
114 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.25802105 |
115 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.25143923 |
116 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.20880722 |
117 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.20040397 |
118 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.19313046 |
119 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.18562305 |
120 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.16490696 |
121 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.15562024 |
122 | Bile secretion_Homo sapiens_hsa04976 | 0.15054223 |