RASL10B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.46524299
2locomotory exploration behavior (GO:0035641)6.22862512
3regulation of short-term neuronal synaptic plasticity (GO:0048172)6.15508666
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.02737875
5regulation of synapse structural plasticity (GO:0051823)5.54526902
6vocalization behavior (GO:0071625)5.45145837
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.44642794
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.33238317
9regulation of glutamate receptor signaling pathway (GO:1900449)5.06602027
10synaptic vesicle docking involved in exocytosis (GO:0016081)5.05852364
11synaptic vesicle exocytosis (GO:0016079)4.98603560
12regulation of long-term neuronal synaptic plasticity (GO:0048169)4.91121763
13regulation of neuronal synaptic plasticity (GO:0048168)4.83382205
14regulation of synaptic vesicle exocytosis (GO:2000300)4.81232604
15glutamate secretion (GO:0014047)4.72590607
16exploration behavior (GO:0035640)4.54922060
17dendritic spine morphogenesis (GO:0060997)4.54281157
18membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.50836811
19layer formation in cerebral cortex (GO:0021819)4.47265930
20protein localization to synapse (GO:0035418)4.45984211
21neurotransmitter-gated ion channel clustering (GO:0072578)4.41875987
22neurotransmitter secretion (GO:0007269)4.41007628
23prepulse inhibition (GO:0060134)4.34037061
24regulation of synaptic vesicle transport (GO:1902803)4.31947493
25ionotropic glutamate receptor signaling pathway (GO:0035235)4.31581645
26regulation of dendritic spine morphogenesis (GO:0061001)4.13885280
27auditory behavior (GO:0031223)4.12695275
28neuronal action potential propagation (GO:0019227)4.11376702
29neuromuscular process controlling balance (GO:0050885)4.04253121
30long-term memory (GO:0007616)4.00927221
31positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.98372221
32positive regulation of membrane potential (GO:0045838)3.97449461
33synaptic transmission, glutamatergic (GO:0035249)3.95634647
34gamma-aminobutyric acid transport (GO:0015812)3.92668934
35positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.92351154
36positive regulation of synaptic transmission, GABAergic (GO:0032230)3.91293499
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.87450080
38activation of protein kinase A activity (GO:0034199)3.86608843
39neuron-neuron synaptic transmission (GO:0007270)3.79892534
40regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.74208259
41response to auditory stimulus (GO:0010996)3.73996311
42sodium ion export (GO:0071436)3.72007742
43cellular potassium ion homeostasis (GO:0030007)3.69045380
44positive regulation of neurotransmitter transport (GO:0051590)3.68821041
45G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.66718295
46regulation of synaptic plasticity (GO:0048167)3.65869772
47glutamate receptor signaling pathway (GO:0007215)3.64700540
48postsynaptic membrane organization (GO:0001941)3.61029875
49regulation of postsynaptic membrane potential (GO:0060078)3.60389894
50neuron cell-cell adhesion (GO:0007158)3.58364576
51glycine transport (GO:0015816)3.54844895
52proline transport (GO:0015824)3.51212845
53positive regulation of neurotransmitter secretion (GO:0001956)3.50894666
54cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.50341552
55striatum development (GO:0021756)3.50171582
56neuronal ion channel clustering (GO:0045161)3.49096915
57negative regulation of cytosolic calcium ion concentration (GO:0051481)3.46821227
58synaptic transmission, dopaminergic (GO:0001963)3.45076084
59adenosine receptor signaling pathway (GO:0001973)3.44670579
60adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.43507985
61regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.43221269
62regulation of synaptic transmission, glutamatergic (GO:0051966)3.42598519
63transmission of nerve impulse (GO:0019226)3.41455598
64neurotransmitter transport (GO:0006836)3.41349053
65behavioral response to nicotine (GO:0035095)3.39614581
66cell communication by electrical coupling (GO:0010644)3.39171890
67dopamine receptor signaling pathway (GO:0007212)3.37335894
68regulation of female receptivity (GO:0045924)3.32573125
69negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.31077857
70regulation of dendritic spine development (GO:0060998)3.30849632
71positive regulation of synapse maturation (GO:0090129)3.30398861
72dendritic spine organization (GO:0097061)3.29028766
73regulation of neurotransmitter levels (GO:0001505)3.27884686
74regulation of neurotransmitter secretion (GO:0046928)3.24838970
75regulation of voltage-gated calcium channel activity (GO:1901385)3.22433658
76behavioral response to cocaine (GO:0048148)3.21810659
77long-term synaptic potentiation (GO:0060291)3.20763810
78positive regulation of dendritic spine development (GO:0060999)3.20557198
79regulation of ARF protein signal transduction (GO:0032012)3.18910875
80membrane hyperpolarization (GO:0060081)3.18457248
81neuromuscular process controlling posture (GO:0050884)3.17474370
82regulation of neurotransmitter transport (GO:0051588)3.15531312
83response to amphetamine (GO:0001975)3.13589746
84membrane depolarization (GO:0051899)3.11555172
85membrane depolarization during action potential (GO:0086010)3.10863757
86neuromuscular process (GO:0050905)3.08012650
87learning (GO:0007612)3.06003992
88visual learning (GO:0008542)3.05732370
89behavioral defense response (GO:0002209)3.05600215
90behavioral fear response (GO:0001662)3.05600215
91vesicle transport along microtubule (GO:0047496)3.05096851
92regulation of nuclear cell cycle DNA replication (GO:0033262)3.04554305
93positive regulation of synaptic transmission (GO:0050806)3.04499066
94regulation of vesicle fusion (GO:0031338)3.04462484
95dendrite morphogenesis (GO:0048813)3.01923858
96mechanosensory behavior (GO:0007638)3.00276105
97regulation of glutamate secretion (GO:0014048)2.95554905
98positive regulation of dendritic spine morphogenesis (GO:0061003)2.93725110
99neuromuscular synaptic transmission (GO:0007274)2.92376196
100synaptic vesicle endocytosis (GO:0048488)2.91239138
101regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.91162199
102neuron recognition (GO:0008038)2.90708165
103cardiac myofibril assembly (GO:0055003)2.90661227
104potassium ion import (GO:0010107)2.89990300
105regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.89263439
106positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.81711548
107cell migration in hindbrain (GO:0021535)2.81019484
108myofibril assembly (GO:0030239)2.73600858
109sarcoplasmic reticulum calcium ion transport (GO:0070296)2.57984830
110regulation of mitochondrial translation (GO:0070129)2.57288367
111presynaptic membrane assembly (GO:0097105)2.56099016
112muscle filament sliding (GO:0030049)2.54975165
113actin-myosin filament sliding (GO:0033275)2.54975165
114positive regulation of sodium ion transmembrane transport (GO:1902307)2.49513980
115regulation of neurotransmitter uptake (GO:0051580)2.49359056
116regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.47051999
117C4-dicarboxylate transport (GO:0015740)2.45696893
118regulation of respiratory system process (GO:0044065)2.45622760
119L-serine metabolic process (GO:0006563)2.44615149
120muscle cell fate commitment (GO:0042693)2.43583766
121axon ensheathment in central nervous system (GO:0032291)2.42066889
122central nervous system myelination (GO:0022010)2.42066889
123regulation of membrane repolarization (GO:0060306)2.40341817
124negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.38079335
125cardiac chamber formation (GO:0003207)2.37027371
126presynaptic membrane organization (GO:0097090)2.36740930
127adult heart development (GO:0007512)2.34801381
128pyrimidine nucleobase catabolic process (GO:0006208)2.32894129
129positive regulation of guanylate cyclase activity (GO:0031284)2.32126447
130cardiac ventricle formation (GO:0003211)2.31961823
131outer ear morphogenesis (GO:0042473)2.30359623
132positive regulation of sodium ion transport (GO:0010765)2.30229117
133regulation of respiratory gaseous exchange (GO:0043576)2.29141725
134skeletal muscle organ development (GO:0060538)2.29072745
135somite development (GO:0061053)2.28817785
136regulation of synapse maturation (GO:0090128)2.28453960
137skeletal muscle fiber development (GO:0048741)2.28238745
138regulation of posttranscriptional gene silencing (GO:0060147)2.25055532
139regulation of gene silencing by miRNA (GO:0060964)2.25055532
140regulation of gene silencing by RNA (GO:0060966)2.25055532
141G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.24320394
142negative regulation of synaptic transmission, GABAergic (GO:0032229)2.22862073
143regulation of cellular respiration (GO:0043457)2.20164568
144thalamus development (GO:0021794)2.19568463
145establishment of mitochondrion localization (GO:0051654)2.17738745
146creatine metabolic process (GO:0006600)2.17198342
147arginine catabolic process (GO:0006527)2.17132206
148axonal fasciculation (GO:0007413)2.15852075
149neurotransmitter uptake (GO:0001504)2.13823804
150respiratory chain complex IV assembly (GO:0008535)2.13299243
151positive regulation of dendrite development (GO:1900006)2.12365338
152cranial nerve morphogenesis (GO:0021602)2.11710150
153striated muscle contraction (GO:0006941)2.11696771
154pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.11676410

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.59806363
2* RARB_27405468_Chip-Seq_BRAIN_Mouse3.44972593
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.10449200
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.08944570
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.04512717
6DROSHA_22980978_ChIP-Seq_HELA_Human2.87992336
7* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.79142142
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.79142142
9MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.78987740
10REST_21632747_ChIP-Seq_MESCs_Mouse2.78906661
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74229407
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.62972618
13GBX2_23144817_ChIP-Seq_PC3_Human2.61501140
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.61252570
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.54538673
16EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.53224558
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50814116
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.47712562
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.38791717
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.38539114
21* EZH2_27294783_Chip-Seq_ESCs_Mouse2.35906440
22* REST_18959480_ChIP-ChIP_MESCs_Mouse2.35608492
23IKZF1_21737484_ChIP-ChIP_HCT116_Human2.26392541
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.25136837
25CBX2_27304074_Chip-Seq_ESCs_Mouse2.06715773
26EED_16625203_ChIP-ChIP_MESCs_Mouse2.04839646
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.99349968
28ERG_21242973_ChIP-ChIP_JURKAT_Human1.93888830
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83934424
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.74574682
31DNAJC2_21179169_ChIP-ChIP_NT2_Human1.64295453
32RNF2_27304074_Chip-Seq_NSC_Mouse1.60905318
33KDM2B_26808549_Chip-Seq_K562_Human1.55706113
34ZFP281_18757296_ChIP-ChIP_E14_Mouse1.52843048
35RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.50791770
36* AR_21572438_ChIP-Seq_LNCaP_Human1.49087673
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48069105
38GATA1_26923725_Chip-Seq_HPCs_Mouse1.46220313
39ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.43259843
40* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.43194449
41TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.42158035
42* RING1B_27294783_Chip-Seq_ESCs_Mouse1.41347166
43* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.38273021
44TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.36910829
45SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.35333046
46WT1_25993318_ChIP-Seq_PODOCYTE_Human1.34290590
47GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.31450052
48GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28833927
49SMAD4_21799915_ChIP-Seq_A2780_Human1.26805516
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23900475
51THAP11_20581084_ChIP-Seq_MESCs_Mouse1.22475293
52CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.22261223
53SOX2_21211035_ChIP-Seq_LN229_Gbm1.21658427
54AR_19668381_ChIP-Seq_PC3_Human1.21051879
55HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.20055972
56* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.20053334
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19690164
58RING1B_27294783_Chip-Seq_NPCs_Mouse1.19272930
59ZFP281_27345836_Chip-Seq_ESCs_Mouse1.17493797
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15982289
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15324834
62TP53_20018659_ChIP-ChIP_R1E_Mouse1.14980526
63P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12664752
64CTCF_27219007_Chip-Seq_Bcells_Human1.12066971
65PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.09840394
66ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.08690848
67KDM2B_26808549_Chip-Seq_SUP-B15_Human1.08332748
68RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.06846772
69CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05418993
70VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.03740048
71ZNF274_21170338_ChIP-Seq_K562_Hela1.03365146
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.02584437
73E2F7_22180533_ChIP-Seq_HELA_Human1.02374737
74TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.02294739
75SMAD3_21741376_ChIP-Seq_HESCs_Human1.02079561
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02049039
77PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01486030
78TET1_21490601_ChIP-Seq_MESCs_Mouse1.00737564
79* TET1_21451524_ChIP-Seq_MESCs_Mouse1.00154393
80DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.99598952
81STAT3_23295773_ChIP-Seq_U87_Human0.99165885
82SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.99125299
83ZNF217_24962896_ChIP-Seq_MCF-7_Human0.97910568
84SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97820740
85MYC_18940864_ChIP-ChIP_HL60_Human0.97050422
86RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.96910093
87SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.96490844
88THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.94544047
89TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.94320639
90ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.94254387
91P68_20966046_ChIP-Seq_HELA_Human0.93870322
92SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93608654
93SMAD4_21741376_ChIP-Seq_HESCs_Human0.93591157
94MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93554522
95FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93536836
96YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93530705
97AR_25329375_ChIP-Seq_VCAP_Human0.92212399
98* ISL1_27105846_Chip-Seq_CPCs_Mouse0.91981438
99TAF15_26573619_Chip-Seq_HEK293_Human0.91931357
100* KLF4_19829295_ChIP-Seq_ESCs_Human0.90645946
101SMAD_19615063_ChIP-ChIP_OVARY_Human0.90023416
102ZFP57_27257070_Chip-Seq_ESCs_Mouse0.87994371
103POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87901959
104GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87603667
105LXR_22292898_ChIP-Seq_THP-1_Human0.87251582
106CDX2_19796622_ChIP-Seq_MESCs_Mouse0.87128603
107HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.86912686
108XRN2_22483619_ChIP-Seq_HELA_Human0.86741206
109SMC4_20622854_ChIP-Seq_HELA_Human0.86524985
110AHR_22903824_ChIP-Seq_MCF-7_Human0.86455583
111RXR_22108803_ChIP-Seq_LS180_Human0.86314579
112ESR1_20079471_ChIP-ChIP_T-47D_Human0.86199460
113* SMAD3_21741376_ChIP-Seq_ESCs_Human0.85936984
114TCF4_23295773_ChIP-Seq_U87_Human0.85300646
115TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84405246
116POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.84405246
117ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.84134087
118MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.84124675
119E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.84080641
120KDM2B_26808549_Chip-Seq_JURKAT_Human0.84004413
121KDM2B_26808549_Chip-Seq_DND41_Human0.82987263
122ARNT_22903824_ChIP-Seq_MCF-7_Human0.82846673
123SOX2_16153702_ChIP-ChIP_HESCs_Human0.81575105
124OCT4_19829295_ChIP-Seq_ESCs_Human0.80508563
125* TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.80471761
126NR3C1_21868756_ChIP-Seq_MCF10A_Human0.79982574
127OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.79801411
128KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.79647414
129TP63_19390658_ChIP-ChIP_HaCaT_Human0.79584689
130EP300_21415370_ChIP-Seq_HL-1_Mouse0.79251854
131FUS_26573619_Chip-Seq_HEK293_Human0.78981667
132TOP2B_26459242_ChIP-Seq_MCF-7_Human0.78634629
133YY1_21170310_ChIP-Seq_MESCs_Mouse0.77402926
134RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76017334
135SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.75545530
136FOXP1_21924763_ChIP-Seq_HESCs_Human0.74552220
137SOX3_22085726_ChIP-Seq_NPCs_Mouse0.74515156
138SOX9_26525672_Chip-Seq_HEART_Mouse0.71708561
139SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.70978523
140* ERA_21632823_ChIP-Seq_H3396_Human0.70583153
141VDR_22108803_ChIP-Seq_LS180_Human0.70401338
142SOX2_18555785_ChIP-Seq_MESCs_Mouse0.70358322
143HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.69253929
144DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.67923017
145OCT4_20526341_ChIP-Seq_ESCs_Human0.67422483

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.16697639
2MP0002822_catalepsy5.51693773
3MP0003635_abnormal_synaptic_transmissio4.29383481
4MP0003880_abnormal_central_pattern4.16710188
5MP0004270_analgesia3.67793390
6MP0009745_abnormal_behavioral_response3.56349422
7MP0002063_abnormal_learning/memory/cond3.48413177
8MP0002064_seizures3.11674467
9MP0009046_muscle_twitch2.88093071
10MP0005423_abnormal_somatic_nervous2.78679466
11MP0000566_synostosis2.76782637
12MP0002572_abnormal_emotion/affect_behav2.74020640
13MP0001486_abnormal_startle_reflex2.65995247
14MP0001968_abnormal_touch/_nociception2.61184955
15MP0002272_abnormal_nervous_system2.49839884
16MP0002734_abnormal_mechanical_nocicepti2.40511919
17MP0002234_abnormal_pharynx_morphology2.30824192
18MP0002909_abnormal_adrenal_gland2.21500363
19MP0001501_abnormal_sleep_pattern2.08464498
20MP0009780_abnormal_chondrocyte_physiolo2.01297008
21MP0008569_lethality_at_weaning1.97848155
22MP0010030_abnormal_orbit_morphology1.88938507
23MP0006292_abnormal_olfactory_placode1.86701424
24MP0001970_abnormal_pain_threshold1.85583118
25MP0004811_abnormal_neuron_physiology1.85161300
26MP0002733_abnormal_thermal_nociception1.83487648
27MP0002736_abnormal_nociception_after1.80539231
28MP0004924_abnormal_behavior1.80298675
29MP0005386_behavior/neurological_phenoty1.80298675
30MP0001440_abnormal_grooming_behavior1.78835040
31MP0004858_abnormal_nervous_system1.75055529
32MP0003329_amyloid_beta_deposits1.72603993
33MP0005646_abnormal_pituitary_gland1.68799211
34MP0002557_abnormal_social/conspecific_i1.67179302
35MP0001529_abnormal_vocalization1.64479390
36MP0002735_abnormal_chemical_nociception1.63364754
37MP0002067_abnormal_sensory_capabilities1.61421799
38MP0003136_yellow_coat_color1.58767155
39MP0004885_abnormal_endolymph1.53625801
40MP0003879_abnormal_hair_cell1.52744293
41MP0000751_myopathy1.48509844
42MP0002184_abnormal_innervation1.48018860
43MP0004133_heterotaxia1.47770981
44MP0002638_abnormal_pupillary_reflex1.47522841
45MP0000955_abnormal_spinal_cord1.44425401
46MP0003633_abnormal_nervous_system1.42778085
47MP0001346_abnormal_lacrimal_gland1.41782153
48MP0000778_abnormal_nervous_system1.40160716
49MP0003075_altered_response_to1.39948905
50MP0002066_abnormal_motor_capabilities/c1.37561052
51MP0001984_abnormal_olfaction1.36737063
52MP0003937_abnormal_limbs/digits/tail_de1.32673285
53MP0000049_abnormal_middle_ear1.31504190
54MP0002882_abnormal_neuron_morphology1.30260052
55MP0003119_abnormal_digestive_system1.21371314
56MP0002249_abnormal_larynx_morphology1.21050596
57MP0008961_abnormal_basal_metabolism1.19911940
58MP0005167_abnormal_blood-brain_barrier1.19542414
59MP0005187_abnormal_penis_morphology1.17672503
60MP0003283_abnormal_digestive_organ1.15513963
61MP0000749_muscle_degeneration1.15376394
62MP0004085_abnormal_heartbeat1.14318373
63MP0001293_anophthalmia1.13566842
64MP0003631_nervous_system_phenotype1.13237227
65MP0008874_decreased_physiological_sensi1.12611344
66MP0005670_abnormal_white_adipose1.09603858
67MP0008872_abnormal_physiological_respon1.08935446
68MP0001502_abnormal_circadian_rhythm1.08858838
69MP0001177_atelectasis1.08162796
70MP0000013_abnormal_adipose_tissue1.07479342
71MP0001905_abnormal_dopamine_level1.06268431
72MP0003137_abnormal_impulse_conducting1.05418753
73MP0003123_paternal_imprinting1.05372756
74MP0003787_abnormal_imprinting1.03556308
75MP0003861_abnormal_nervous_system1.03402110
76MP0004215_abnormal_myocardial_fiber1.03229222
77MP0003942_abnormal_urinary_system1.03225140
78MP0003690_abnormal_glial_cell1.02847247
79MP0002152_abnormal_brain_morphology1.02323182
80MP0002837_dystrophic_cardiac_calcinosis1.00390936
81MP0002106_abnormal_muscle_physiology0.98677298
82MP0003567_abnormal_fetal_cardiomyocyte0.98328057
83MP0005645_abnormal_hypothalamus_physiol0.96784796
84MP0002938_white_spotting0.94999083
85MP0004142_abnormal_muscle_tone0.94963237
86MP0000537_abnormal_urethra_morphology0.94960046
87MP0005409_darkened_coat_color0.94168674
88MP0000569_abnormal_digit_pigmentation0.93951145
89MP0002069_abnormal_eating/drinking_beha0.93729556
90MP0002090_abnormal_vision0.92285768
91MP0005535_abnormal_body_temperature0.90916997
92MP0002233_abnormal_nose_morphology0.90119287
93MP0000534_abnormal_ureter_morphology0.88627495
94MP0000920_abnormal_myelination0.86341116
95MP0003646_muscle_fatigue0.85859504
96MP0010234_abnormal_vibrissa_follicle0.85614534
97MP0006276_abnormal_autonomic_nervous0.85036468
98MP0005369_muscle_phenotype0.84839286
99MP0002229_neurodegeneration0.84714855
100MP0009250_abnormal_appendicular_skeleto0.83570939
101MP0008775_abnormal_heart_ventricle0.81648547
102MP0003634_abnormal_glial_cell0.81576770
103MP0004087_abnormal_muscle_fiber0.80872739
104MP0001299_abnormal_eye_distance/0.80567009
105MP0003121_genomic_imprinting0.79363928
106MP0004130_abnormal_muscle_cell0.78840172
107MP0002102_abnormal_ear_morphology0.77783421
108MP0003938_abnormal_ear_development0.76846370
109MP0009053_abnormal_anal_canal0.75954329
110MP0001188_hyperpigmentation0.75788164
111MP0004145_abnormal_muscle_electrophysio0.74723423
112MP0000604_amyloidosis0.74313658
113MP0004510_myositis0.73915856
114MP0004233_abnormal_muscle_weight0.72957117
115MP0002653_abnormal_ependyma_morphology0.72188063
116MP0005394_taste/olfaction_phenotype0.71249145
117MP0005499_abnormal_olfactory_system0.71249145
118MP0000026_abnormal_inner_ear0.71242073
119MP0005551_abnormal_eye_electrophysiolog0.70025605
120MP0005623_abnormal_meninges_morphology0.69997960
121MP0003632_abnormal_nervous_system0.69128743
122MP0004484_altered_response_of0.68617981
123MP0003122_maternal_imprinting0.64408616
124MP0004036_abnormal_muscle_relaxation0.64124502
125MP0005620_abnormal_muscle_contractility0.63884670
126MP0004043_abnormal_pH_regulation0.60386788
127MP0000631_abnormal_neuroendocrine_gland0.58878283
128MP0005166_decreased_susceptibility_to0.57937070
129MP0000747_muscle_weakness0.55468735
130MP0003172_abnormal_lysosome_physiology0.55123196
131MP0002752_abnormal_somatic_nervous0.54045228
132MP0001485_abnormal_pinna_reflex0.52946762
133MP0004084_abnormal_cardiac_muscle0.52195503
134MP0001963_abnormal_hearing_physiology0.51257872
135MP0002972_abnormal_cardiac_muscle0.51207376
136MP0001664_abnormal_digestion0.50998557

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)8.43511467
2Focal motor seizures (HP:0011153)7.02131913
3Focal seizures (HP:0007359)5.42092205
4Visual hallucinations (HP:0002367)5.02721098
5Action tremor (HP:0002345)4.17754983
6Ankle clonus (HP:0011448)3.98770061
7Epileptic encephalopathy (HP:0200134)3.85180086
8Poor eye contact (HP:0000817)3.75960868
9Impaired vibration sensation in the lower limbs (HP:0002166)3.65264900
10Depression (HP:0000716)3.64553838
11Torticollis (HP:0000473)3.54674731
12Febrile seizures (HP:0002373)3.53345908
13Generalized tonic-clonic seizures (HP:0002069)3.52402161
14Progressive cerebellar ataxia (HP:0002073)3.50136840
15Annular pancreas (HP:0001734)3.49127722
16Anxiety (HP:0000739)3.48048590
17Papilledema (HP:0001085)3.45667990
18Absence seizures (HP:0002121)3.43657750
19Impaired social interactions (HP:0000735)3.42845702
20Abnormal social behavior (HP:0012433)3.42845702
21Atonic seizures (HP:0010819)3.38661294
22Supranuclear gaze palsy (HP:0000605)3.38391267
23Urinary bladder sphincter dysfunction (HP:0002839)3.36958765
24Ventricular fibrillation (HP:0001663)3.35065117
25Dysdiadochokinesis (HP:0002075)3.32315333
26Broad-based gait (HP:0002136)3.29781940
27Postural instability (HP:0002172)3.26734905
28Focal dystonia (HP:0004373)3.16318084
29Dialeptic seizures (HP:0011146)3.13060703
30Gaze-evoked nystagmus (HP:0000640)3.08853044
31Urinary urgency (HP:0000012)3.08334522
32Bundle branch block (HP:0011710)3.04420259
33Resting tremor (HP:0002322)3.03049378
34Dysmetria (HP:0001310)3.01557562
35Mutism (HP:0002300)3.01107592
36Abnormality of the lower motor neuron (HP:0002366)2.96219804
37Craniofacial dystonia (HP:0012179)2.93764839
38Abnormal eating behavior (HP:0100738)2.80487115
39Dysmetric saccades (HP:0000641)2.79337294
40Muscle fiber inclusion bodies (HP:0100299)2.76632746
41Pointed chin (HP:0000307)2.75933088
42Truncal ataxia (HP:0002078)2.73099931
43Intention tremor (HP:0002080)2.71933680
44Megalencephaly (HP:0001355)2.71593363
45Prolonged QT interval (HP:0001657)2.69575902
46Stereotypic behavior (HP:0000733)2.69247422
47Spastic gait (HP:0002064)2.65935242
48Abnormal EKG (HP:0003115)2.65265634
49Nemaline bodies (HP:0003798)2.62672310
50Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.61363852
51Exercise-induced muscle cramps (HP:0003710)2.58661085
52Hemiplegia (HP:0002301)2.57346792
53Lower limb amyotrophy (HP:0007210)2.56368925
54Impaired smooth pursuit (HP:0007772)2.55497840
55Double outlet right ventricle (HP:0001719)2.54981333
56Congenital malformation of the right heart (HP:0011723)2.54981333
57Bradykinesia (HP:0002067)2.54808798
58Ankyloglossia (HP:0010296)2.52431197
59Genetic anticipation (HP:0003743)2.51204961
60Scanning speech (HP:0002168)2.47770150
61Amblyopia (HP:0000646)2.46971160
62Impaired vibratory sensation (HP:0002495)2.44287926
63Abnormality of the aortic arch (HP:0012303)2.43077804
64Colon cancer (HP:0003003)2.37525553
65Insomnia (HP:0100785)2.36267431
66Sudden death (HP:0001699)2.34409812
67Transposition of the great arteries (HP:0001669)2.33661075
68Abnormal connection of the cardiac segments (HP:0011545)2.33661075
69Abnormal ventriculo-arterial connection (HP:0011563)2.33661075
70Hemiparesis (HP:0001269)2.32763897
71Periauricular skin pits (HP:0100277)2.32700053
72Preauricular pit (HP:0004467)2.32700053
73Heart block (HP:0012722)2.32085180
74Progressive inability to walk (HP:0002505)2.29286643
75Lower limb muscle weakness (HP:0007340)2.27580873
76Myotonia (HP:0002486)2.26851778
77Obstructive sleep apnea (HP:0002870)2.26644514
78Muscle hypertrophy of the lower extremities (HP:0008968)2.23885100
79Maternal diabetes (HP:0009800)2.22472948
80Atrioventricular block (HP:0001678)2.22179143
81Neurofibrillary tangles (HP:0002185)2.21787044
82Type II lissencephaly (HP:0007260)2.21625168
83Abnormality of ocular smooth pursuit (HP:0000617)2.20480656
84Clonus (HP:0002169)2.18504060
85Myopathic facies (HP:0002058)2.15601187
86Abnormality of cochlea (HP:0000375)2.13429440
87Cerebral inclusion bodies (HP:0100314)2.12543185
88Intestinal fistula (HP:0100819)2.12372610
89Primary atrial arrhythmia (HP:0001692)2.12267237
90Limb dystonia (HP:0002451)2.10752438
91Type 1 muscle fiber predominance (HP:0003803)2.10567526
92Insidious onset (HP:0003587)2.10334894
93Termporal pattern (HP:0011008)2.10334894
94Abnormal atrioventricular conduction (HP:0005150)2.09953302
95Status epilepticus (HP:0002133)2.09902948
96Atrial fibrillation (HP:0005110)2.08847694
97Calf muscle hypertrophy (HP:0008981)2.07894680
98Abnormality of binocular vision (HP:0011514)2.07461472
99Diplopia (HP:0000651)2.07461472
100Incomplete penetrance (HP:0003829)2.05870989
101Lower limb asymmetry (HP:0100559)2.03937621
102Hyperventilation (HP:0002883)2.02772796
103Drooling (HP:0002307)2.02320580
104Excessive salivation (HP:0003781)2.02320580
105Anophthalmia (HP:0000528)2.02262439
106Fetal akinesia sequence (HP:0001989)2.01817580
107Abnormal number of incisors (HP:0011064)2.01361167
108Pheochromocytoma (HP:0002666)2.00193130
109Retinal dysplasia (HP:0007973)1.99972555
110Supraventricular tachycardia (HP:0004755)1.98461041
111Syncope (HP:0001279)1.95507192
112Rapidly progressive (HP:0003678)1.93246855
113Turricephaly (HP:0000262)1.92606767
114Preaxial foot polydactyly (HP:0001841)1.92285289
115Epileptiform EEG discharges (HP:0011182)1.92247635
116Polygenic inheritance (HP:0010982)1.92094939
117EEG with generalized epileptiform discharges (HP:0011198)1.92020359
118Supraventricular arrhythmia (HP:0005115)1.91894616
119Abnormality of the periventricular white matter (HP:0002518)1.91769005
120Abnormality of saccadic eye movements (HP:0000570)1.91198102
121Ectopic kidney (HP:0000086)1.90540614
122Exercise-induced myalgia (HP:0003738)1.90390032
123Hypsarrhythmia (HP:0002521)1.89529072
124Neoplasm of the peripheral nervous system (HP:0100007)1.87654754
125Neuronal loss in central nervous system (HP:0002529)1.87550084
126Rigidity (HP:0002063)1.86797284
127Rib fusion (HP:0000902)1.86360594
128Abnormality of alanine metabolism (HP:0010916)1.86031029
129Hyperalaninemia (HP:0003348)1.86031029
130Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.86031029
131Morphological abnormality of the inner ear (HP:0011390)1.85267637
132Apathy (HP:0000741)1.85131589
133Subaortic stenosis (HP:0001682)1.82064642
134Abnormality of the left ventricular outflow tract (HP:0011103)1.82064642
135Sclerocornea (HP:0000647)1.80720066
136Abnormality of the corticospinal tract (HP:0002492)1.80516008
137Bilateral microphthalmos (HP:0007633)1.77163233
138Calcaneovalgus deformity (HP:0001848)1.75400673
139Optic nerve hypoplasia (HP:0000609)1.73195836
140Short 5th finger (HP:0009237)1.69907123
141Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.67394194
142Cerebellar dysplasia (HP:0007033)1.65618055
143Supernumerary spleens (HP:0009799)1.64638776
144Anal stenosis (HP:0002025)1.62653449
145Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.59873410
146Septo-optic dysplasia (HP:0100842)1.59583185
147Unsteady gait (HP:0002317)1.58953690
148High anterior hairline (HP:0009890)1.58102756
149Renal dysplasia (HP:0000110)1.57953297
150Type 2 muscle fiber atrophy (HP:0003554)1.57648885
151Frequent falls (HP:0002359)1.56571086
152Concave nail (HP:0001598)1.56432318
153Truncus arteriosus (HP:0001660)1.55301232
154Cutaneous finger syndactyly (HP:0010554)1.54207703
155Left ventricular hypertrophy (HP:0001712)1.53439667
156Coronal craniosynostosis (HP:0004440)1.52682183
157Birth length less than 3rd percentile (HP:0003561)1.52562825
158Muscle fiber atrophy (HP:0100295)1.52021596
159Aplasia involving bones of the extremities (HP:0009825)1.51714479
160Aplasia involving bones of the upper limbs (HP:0009823)1.51714479
161Aplasia of the phalanges of the hand (HP:0009802)1.51714479
162Lissencephaly (HP:0001339)1.51125799
163Deformed tarsal bones (HP:0008119)1.50787814
164Rimmed vacuoles (HP:0003805)1.50056255
165Severe muscular hypotonia (HP:0006829)1.50025082
166Shawl scrotum (HP:0000049)1.49847306
167Depressed nasal tip (HP:0000437)1.49727514
168Infantile muscular hypotonia (HP:0008947)1.49176835

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.76022631
2MAP3K93.99025878
3NTRK33.98334986
4PRKD32.98981966
5DAPK22.91213864
6WNK42.87406431
7OBSCN2.77722537
8MARK12.69925790
9KSR22.65999461
10MINK12.53747668
11CAMKK12.38537540
12PAK62.32990441
13MAP3K42.29143425
14ZAK2.14090194
15EEF2K2.12712304
16NTRK22.03035873
17NTRK11.89533942
18CAMK1D1.81018981
19RIPK41.72360209
20KSR11.66123197
21TAOK11.65823930
22STK391.65185270
23MAP2K71.63773654
24CDK51.62244777
25CASK1.61561460
26STK241.61499865
27CAMK1G1.60337797
28DYRK21.51576135
29STK381.50103843
30DAPK11.49654275
31ARAF1.49515477
32CHEK21.48812724
33TYRO31.48045831
34FES1.41378833
35MAP3K21.39713385
36MAP3K131.39524746
37MAP2K41.38298153
38VRK21.31182041
39SIK21.30717064
40CDC71.29483105
41PRPF4B1.27385375
42LMTK21.26094007
43PINK11.24579762
44PHKG11.23420022
45PHKG21.23420022
46CSNK1G31.17501527
47MUSK1.16192266
48TNIK1.13445121
49MAPKAPK51.12047803
50NEK11.11800651
51TAF11.11113800
52UHMK11.09394722
53CSNK1G11.09334776
54WNK31.08841832
55PRKCH1.08449721
56CAMKK21.06173081
57ALK1.05474257
58GRK51.03351922
59PRKCG1.02430072
60CAMK11.00367815
61STK111.00040237
62RIPK10.98602633
63RAF10.97868773
64CSNK1A1L0.97311572
65MAP3K120.92363714
66SGK4940.90157955
67SGK2230.90157955
68PKN10.89913632
69RET0.89907871
70CDK150.88631761
71CDK180.87457219
72MAPK130.86977283
73BCKDK0.86154541
74PLK20.83996194
75CCNB10.83911182
76TRIB30.83505037
77CDK140.83255084
78CDK190.82424607
79FGFR20.81985004
80LATS20.81829414
81MARK20.80763124
82SGK30.80413334
83CAMK2A0.79591662
84PDK10.79130915
85CDK11A0.77313612
86PDPK10.77044813
87PAK30.74251286
88DMPK0.72423937
89SGK20.71467199
90BRAF0.71339740
91MAP3K10.71146096
92SGK10.70957007
93BRSK10.69680762
94NME10.69543210
95TLK10.67197458
96MAPK120.66956669
97PTK2B0.65593538
98PRKAA10.62780969
99ILK0.60750726
100DAPK30.60597204
101CAMK40.59461094
102CAMK2B0.58416501
103EPHB20.55772050
104TNK20.55355806
105RPS6KA30.54996586
106CDC42BPA0.54462681
107STK160.54189260
108LIMK10.53826849
109MAP3K70.53586332
110PRKCZ0.52993315
111FRK0.52655054
112BMPR20.50698252
113FYN0.50471770
114SCYL20.49759315
115PLK30.47722587
116MAP2K10.47321721
117AKT20.47230434
118NEK60.46545317
119RPS6KA60.45768851
120MAPK100.45052064
121GRK10.44589406
122TTN0.43764915
123RPS6KA50.43760167
124DYRK1A0.43718694
125ATR0.43186016
126PDGFRA0.42882766
127TTK0.42191950
128PRKD20.41000405
129CSNK1G20.40730621
130WNK10.40654367
131BMPR1B0.40558706
132PNCK0.39563196
133AURKA0.39249812
134CAMK2D0.39166758
135VRK10.39072883
136PRKCI0.38436573
137CAMK2G0.36117042
138RPS6KA20.35624567
139PKN20.34697882
140PRKCE0.33665865
141PRKD10.31368374
142DDR20.31099919
143PRKCB0.30627284
144ICK0.30048174
145ROCK10.29619174
146PRKACG0.27916755

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047403.25986737
2Synaptic vesicle cycle_Homo sapiens_hsa047212.98051783
3Nicotine addiction_Homo sapiens_hsa050332.92742441
4Circadian entrainment_Homo sapiens_hsa047132.67687420
5GABAergic synapse_Homo sapiens_hsa047272.62591409
6Long-term potentiation_Homo sapiens_hsa047202.53390632
7Morphine addiction_Homo sapiens_hsa050322.53363266
8Glutamatergic synapse_Homo sapiens_hsa047242.48045135
9Amphetamine addiction_Homo sapiens_hsa050312.45510951
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.32764218
11Dopaminergic synapse_Homo sapiens_hsa047282.18487939
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.16685295
13Vitamin B6 metabolism_Homo sapiens_hsa007502.14866591
14Cholinergic synapse_Homo sapiens_hsa047252.07764812
15Salivary secretion_Homo sapiens_hsa049702.06499557
16Sulfur relay system_Homo sapiens_hsa041222.05352438
17Nitrogen metabolism_Homo sapiens_hsa009101.97236435
18Cocaine addiction_Homo sapiens_hsa050301.97182665
19Gastric acid secretion_Homo sapiens_hsa049711.93682411
20Insulin secretion_Homo sapiens_hsa049111.93247454
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.92122559
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.90378624
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.88321949
24Oxytocin signaling pathway_Homo sapiens_hsa049211.73380780
25Renin secretion_Homo sapiens_hsa049241.71153039
26Parkinsons disease_Homo sapiens_hsa050121.68825034
27Arginine and proline metabolism_Homo sapiens_hsa003301.61236330
28Calcium signaling pathway_Homo sapiens_hsa040201.58220095
29Oxidative phosphorylation_Homo sapiens_hsa001901.52166476
30GnRH signaling pathway_Homo sapiens_hsa049121.48676176
31Gap junction_Homo sapiens_hsa045401.45077645
32Long-term depression_Homo sapiens_hsa047301.44484796
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.42197944
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.38029438
35Serotonergic synapse_Homo sapiens_hsa047261.37881642
36Taste transduction_Homo sapiens_hsa047421.37033771
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36262303
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.36183288
39Ribosome_Homo sapiens_hsa030101.35518305
40cAMP signaling pathway_Homo sapiens_hsa040241.33784581
41Basal cell carcinoma_Homo sapiens_hsa052171.33447015
42Alzheimers disease_Homo sapiens_hsa050101.31790454
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.28007785
44Glioma_Homo sapiens_hsa052141.25786876
45Type II diabetes mellitus_Homo sapiens_hsa049301.22962609
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.14549533
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.14371374
48Huntingtons disease_Homo sapiens_hsa050161.14281548
49Estrogen signaling pathway_Homo sapiens_hsa049151.13759245
50Cardiac muscle contraction_Homo sapiens_hsa042601.11566489
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.09587883
52Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07629785
53Biosynthesis of amino acids_Homo sapiens_hsa012301.07101240
54Dilated cardiomyopathy_Homo sapiens_hsa054141.06242587
55RNA polymerase_Homo sapiens_hsa030201.02177932
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.00990907
57Melanogenesis_Homo sapiens_hsa049161.00896757
58Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.00660470
59Selenocompound metabolism_Homo sapiens_hsa004501.00052330
60Propanoate metabolism_Homo sapiens_hsa006401.00047561
61ErbB signaling pathway_Homo sapiens_hsa040120.99150719
62Hedgehog signaling pathway_Homo sapiens_hsa043400.98619820
63Lysine degradation_Homo sapiens_hsa003100.98206357
64Pyruvate metabolism_Homo sapiens_hsa006200.98197491
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.96439766
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.95913658
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.95781430
68Hippo signaling pathway_Homo sapiens_hsa043900.94394453
69Axon guidance_Homo sapiens_hsa043600.93344068
70Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.93067484
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.91553175
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90926933
73Oocyte meiosis_Homo sapiens_hsa041140.89145838
74Dorso-ventral axis formation_Homo sapiens_hsa043200.87409084
75One carbon pool by folate_Homo sapiens_hsa006700.87051145
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87046212
77Butanoate metabolism_Homo sapiens_hsa006500.86254523
78DNA replication_Homo sapiens_hsa030300.83799839
79Base excision repair_Homo sapiens_hsa034100.83323218
80AMPK signaling pathway_Homo sapiens_hsa041520.82872383
81Pyrimidine metabolism_Homo sapiens_hsa002400.80674083
82Purine metabolism_Homo sapiens_hsa002300.78871391
83Pancreatic secretion_Homo sapiens_hsa049720.77509226
84Collecting duct acid secretion_Homo sapiens_hsa049660.77063392
85Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76738040
86Fanconi anemia pathway_Homo sapiens_hsa034600.76393211
87Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.75428328
88Thyroid hormone synthesis_Homo sapiens_hsa049180.74874274
89VEGF signaling pathway_Homo sapiens_hsa043700.73304246
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.72312878
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71605304
92Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.70903478
93Non-small cell lung cancer_Homo sapiens_hsa052230.70234820
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.69986821
95Phototransduction_Homo sapiens_hsa047440.69504759
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.68579314
97Choline metabolism in cancer_Homo sapiens_hsa052310.68058740
98MAPK signaling pathway_Homo sapiens_hsa040100.67637695
99mTOR signaling pathway_Homo sapiens_hsa041500.67156703
100Rap1 signaling pathway_Homo sapiens_hsa040150.66501833
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65549804
102Fatty acid metabolism_Homo sapiens_hsa012120.64870680
103Carbon metabolism_Homo sapiens_hsa012000.63278977
104Alcoholism_Homo sapiens_hsa050340.63143858
105Bile secretion_Homo sapiens_hsa049760.62609432
106beta-Alanine metabolism_Homo sapiens_hsa004100.61986433
107Glucagon signaling pathway_Homo sapiens_hsa049220.61787689
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61685061
109Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.61222063
110Endocytosis_Homo sapiens_hsa041440.58287469
111Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.56592509
112Homologous recombination_Homo sapiens_hsa034400.56542644
113Endometrial cancer_Homo sapiens_hsa052130.56244834
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54830020
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.54811976
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54810482
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54078481
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53617226
119Ras signaling pathway_Homo sapiens_hsa040140.53608406
120Type I diabetes mellitus_Homo sapiens_hsa049400.53433690
121Fat digestion and absorption_Homo sapiens_hsa049750.53316619
122Fatty acid biosynthesis_Homo sapiens_hsa000610.53216500
123Steroid biosynthesis_Homo sapiens_hsa001000.52921611
124Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52165244
125Tight junction_Homo sapiens_hsa045300.50938950
126Basal transcription factors_Homo sapiens_hsa030220.50613751
127Insulin signaling pathway_Homo sapiens_hsa049100.50437354
128RNA degradation_Homo sapiens_hsa030180.50374702
129mRNA surveillance pathway_Homo sapiens_hsa030150.50010375
130Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49519109
131Vibrio cholerae infection_Homo sapiens_hsa051100.48173379
132Prion diseases_Homo sapiens_hsa050200.47688825
133Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47645731
134Renal cell carcinoma_Homo sapiens_hsa052110.46892761
135Chemokine signaling pathway_Homo sapiens_hsa040620.46084578
136Inositol phosphate metabolism_Homo sapiens_hsa005620.41031562
137Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39929485
138Arginine biosynthesis_Homo sapiens_hsa002200.38597959
139Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37656687
140Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.37355835
141Circadian rhythm_Homo sapiens_hsa047100.35077235
142Ovarian steroidogenesis_Homo sapiens_hsa049130.34952786
143Platelet activation_Homo sapiens_hsa046110.33859884
144Central carbon metabolism in cancer_Homo sapiens_hsa052300.31948879
145Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.29710672
146Wnt signaling pathway_Homo sapiens_hsa043100.29578497
147Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29240699
148Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.29212196
149Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.27048406

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