RBM11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)5.26013716
2axon ensheathment in central nervous system (GO:0032291)5.26013716
3piRNA metabolic process (GO:0034587)4.78471736
4long-chain fatty acid biosynthetic process (GO:0042759)4.46236118
5neuron cell-cell adhesion (GO:0007158)4.33340353
6regulation of meiosis I (GO:0060631)4.28931961
7presynaptic membrane organization (GO:0097090)4.26550490
8presynaptic membrane assembly (GO:0097105)4.17870821
9positive regulation of histone H3-K4 methylation (GO:0051571)3.92817490
10inositol phosphate dephosphorylation (GO:0046855)3.85523718
11phosphorylated carbohydrate dephosphorylation (GO:0046838)3.85523718
12protein localization to cilium (GO:0061512)3.79454339
13inositol phosphate catabolic process (GO:0071545)3.75364281
14neurofilament cytoskeleton organization (GO:0060052)3.75325621
15DNA methylation involved in gamete generation (GO:0043046)3.72746462
16synapsis (GO:0007129)3.67841036
17cullin deneddylation (GO:0010388)3.65204893
18negative regulation of DNA-dependent DNA replication (GO:2000104)3.54773652
19respiratory chain complex IV assembly (GO:0008535)3.50283902
20negative regulation of neurotransmitter transport (GO:0051589)3.50243662
21protein localization to synapse (GO:0035418)3.49659181
22glycerophospholipid catabolic process (GO:0046475)3.49385658
23single strand break repair (GO:0000012)3.48578329
24adrenergic receptor signaling pathway (GO:0071875)3.44045477
25mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.41094810
26protein deneddylation (GO:0000338)3.37504399
27chromatin remodeling at centromere (GO:0031055)3.37425943
28synaptic vesicle exocytosis (GO:0016079)3.36196753
29neuronal action potential propagation (GO:0019227)3.32034329
30CENP-A containing nucleosome assembly (GO:0034080)3.27998708
31male meiosis (GO:0007140)3.26733512
32eye photoreceptor cell differentiation (GO:0001754)3.18428534
33photoreceptor cell differentiation (GO:0046530)3.18428534
34response to redox state (GO:0051775)3.17088855
35proline transport (GO:0015824)3.16948936
36mitotic sister chromatid cohesion (GO:0007064)3.14024076
37negative regulation of synaptic transmission, GABAergic (GO:0032229)3.13714700
38detection of temperature stimulus involved in sensory perception (GO:0050961)3.12517873
39detection of temperature stimulus involved in sensory perception of pain (GO:0050965)3.12517873
40nonmotile primary cilium assembly (GO:0035058)3.07179614
41polyol catabolic process (GO:0046174)3.06712307
42regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.05866323
43fatty acid elongation (GO:0030497)3.05811603
44protein neddylation (GO:0045116)3.04848229
45neuron fate determination (GO:0048664)3.03883177
46acrosome reaction (GO:0007340)2.99082888
47transmission of nerve impulse (GO:0019226)2.99061717
48centriole replication (GO:0007099)2.96431238
49intra-S DNA damage checkpoint (GO:0031573)2.96278626
50meiotic cell cycle (GO:0051321)2.96240950
51neuronal action potential (GO:0019228)2.95114905
52cytochrome complex assembly (GO:0017004)2.92657471
53short-term memory (GO:0007614)2.92616323
54negative regulation of neurotransmitter secretion (GO:0046929)2.89228244
55postsynaptic membrane organization (GO:0001941)2.85451829
56righting reflex (GO:0060013)2.85265883
57peripheral nervous system neuron development (GO:0048935)2.84389067
58calcium-mediated signaling using intracellular calcium source (GO:0035584)2.83879885
59regulation of neurotransmitter uptake (GO:0051580)2.82078369
60ER overload response (GO:0006983)2.80807539
61male meiosis I (GO:0007141)2.80065167
62neuron-neuron synaptic transmission (GO:0007270)2.79659918
63synaptic vesicle maturation (GO:0016188)2.78032400
64histone exchange (GO:0043486)2.77849560
65detection of temperature stimulus (GO:0016048)2.76976895
66behavioral response to cocaine (GO:0048148)2.76972073
67dopamine biosynthetic process (GO:0042416)2.76588246
68establishment of protein localization to mitochondrial membrane (GO:0090151)2.73381239
69startle response (GO:0001964)2.73296568
70regulation of DNA endoreduplication (GO:0032875)2.72553956
71signal peptide processing (GO:0006465)2.72484969
72regulation of synaptic vesicle exocytosis (GO:2000300)2.72387483
73vocalization behavior (GO:0071625)2.72172098
74detection of mechanical stimulus involved in sensory perception (GO:0050974)2.70887017
75glutamate secretion (GO:0014047)2.69687002
76regulation of centriole replication (GO:0046599)2.69616505
77ionotropic glutamate receptor signaling pathway (GO:0035235)2.67919892
78serotonin receptor signaling pathway (GO:0007210)2.67869565
79gamma-aminobutyric acid signaling pathway (GO:0007214)2.67279274
80regulation of neurotransmitter secretion (GO:0046928)2.65578070
81protein K6-linked ubiquitination (GO:0085020)2.64291906
82synaptic transmission, glutamatergic (GO:0035249)2.63314855
83regulation of rhodopsin mediated signaling pathway (GO:0022400)2.63256077
84retinal cone cell development (GO:0046549)2.63230579
85cranial nerve development (GO:0021545)2.63096160
86glutamate receptor signaling pathway (GO:0007215)2.62878970
87negative regulation of dendrite morphogenesis (GO:0050774)2.62114984
88neurotransmitter uptake (GO:0001504)2.61274510
89positive regulation of dendritic spine morphogenesis (GO:0061003)2.61183356
90protein polyglutamylation (GO:0018095)2.60872256
91behavioral response to pain (GO:0048266)2.60750434
92neuron recognition (GO:0008038)2.60101855
93sister chromatid cohesion (GO:0007062)2.59206255
94pteridine-containing compound biosynthetic process (GO:0042559)2.59062477
95behavioral response to nicotine (GO:0035095)2.58998152
96synaptic transmission, dopaminergic (GO:0001963)2.58670783
97adult walking behavior (GO:0007628)2.58608172
98mitochondrial respiratory chain complex assembly (GO:0033108)2.56787116
99positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.54616103
100rhodopsin mediated signaling pathway (GO:0016056)2.54055483
101positive regulation of oligodendrocyte differentiation (GO:0048714)2.53798166
102nucleotide-excision repair, DNA gap filling (GO:0006297)2.53168492
103regulation of respiratory system process (GO:0044065)2.53080571
104intraciliary transport (GO:0042073)2.52778997
105membrane assembly (GO:0071709)2.52400028
106myelination (GO:0042552)2.52340368
107synaptic vesicle endocytosis (GO:0048488)2.51815684
108neuromuscular synaptic transmission (GO:0007274)2.51712768
109positive regulation of meiosis (GO:0045836)2.51578474
110positive regulation of synaptic transmission, GABAergic (GO:0032230)2.51175619
111regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.50724265
112mechanosensory behavior (GO:0007638)2.50476357
113regulation of voltage-gated calcium channel activity (GO:1901385)2.49787863
114response to phenylpropanoid (GO:0080184)2.49598653
115positive regulation of synapse assembly (GO:0051965)2.48999916
116regulation of dopamine metabolic process (GO:0042053)2.48979125
117regulation of catecholamine metabolic process (GO:0042069)2.48979125
118retinal ganglion cell axon guidance (GO:0031290)2.48886345
119mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.48214118
120cerebral cortex radially oriented cell migration (GO:0021799)2.48173240
121negative regulation of execution phase of apoptosis (GO:1900118)2.48010610
122photoreceptor cell maintenance (GO:0045494)2.47625599
123dorsal/ventral neural tube patterning (GO:0021904)2.47330466
124calcium ion-dependent exocytosis (GO:0017156)2.46662942
125axon ensheathment (GO:0008366)2.45969267
126ensheathment of neurons (GO:0007272)2.45969267
127protein-cofactor linkage (GO:0018065)2.45081635
128positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.44219049
129retinal rod cell development (GO:0046548)2.44090876
130regulation of respiratory gaseous exchange (GO:0043576)2.43764622
131detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.43217588
132positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.42545039
133regulation of neurotransmitter transport (GO:0051588)2.42508703
134regulation of synaptic vesicle transport (GO:1902803)2.41538829
135regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.41493428
136regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.41493428
137negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.41176518
138regulation of pigment cell differentiation (GO:0050932)2.40798498
139chaperone-mediated protein transport (GO:0072321)2.40474150
140GPI anchor biosynthetic process (GO:0006506)2.40385345
141G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.39057116
142dopamine transport (GO:0015872)2.38981092
143mitochondrial respiratory chain complex I assembly (GO:0032981)2.38928124
144NADH dehydrogenase complex assembly (GO:0010257)2.38928124
145mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.38928124
146regulation of collateral sprouting (GO:0048670)2.38393959
147regulation of mitochondrial translation (GO:0070129)2.37469152
148DNA replication checkpoint (GO:0000076)2.36923190
149mannosylation (GO:0097502)2.36480689
150synapse assembly (GO:0007416)2.36072657
151adult behavior (GO:0030534)2.36005729
152regulation of glutamate secretion (GO:0014048)2.35780037
153adult locomotory behavior (GO:0008344)2.35357111
154early endosome to late endosome transport (GO:0045022)2.34700080
155regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.34318520
156regulation of platelet aggregation (GO:0090330)2.34211654
157protein complex biogenesis (GO:0070271)2.33401875
158response to cocaine (GO:0042220)2.32865447
159positive regulation of histone methylation (GO:0031062)2.32061493
160regulation of short-term neuronal synaptic plasticity (GO:0048172)2.31987235
161negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.31554429
162positive regulation of meiotic cell cycle (GO:0051446)2.31421394
163ketone body metabolic process (GO:1902224)2.30846244
164axoneme assembly (GO:0035082)2.30583983
165water-soluble vitamin biosynthetic process (GO:0042364)2.30576952
166adaptation of signaling pathway (GO:0023058)2.30266724
167recombinational repair (GO:0000725)2.30254145
168positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.30075015
169atrial cardiac muscle cell action potential (GO:0086014)2.29807818
170spermatid development (GO:0007286)2.29385347
171establishment of melanosome localization (GO:0032401)2.29005177
172double-strand break repair via homologous recombination (GO:0000724)2.27847739
173chromosome organization involved in meiosis (GO:0070192)2.27023356
174pyrimidine dimer repair (GO:0006290)2.26938996
175lactate metabolic process (GO:0006089)2.23939877
176regulation of glucokinase activity (GO:0033131)2.23713732
177regulation of hexokinase activity (GO:1903299)2.23713732
178protein prenylation (GO:0018342)2.22956872
179prenylation (GO:0097354)2.22956872
180nitric oxide biosynthetic process (GO:0006809)2.22886577
181positive regulation of mitotic sister chromatid separation (GO:1901970)2.21999478
182positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.21999478
183positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.21999478
184regulation of cilium movement (GO:0003352)2.21521045
185negative regulation of hormone biosynthetic process (GO:0032353)2.21005767
186regulation of double-strand break repair via homologous recombination (GO:0010569)2.20873341
187DNA replication-independent nucleosome assembly (GO:0006336)2.20720355
188DNA replication-independent nucleosome organization (GO:0034724)2.20720355
189electron transport chain (GO:0022900)2.20363856
190respiratory electron transport chain (GO:0022904)2.20001833
191rRNA catabolic process (GO:0016075)2.19655754
192ATP synthesis coupled proton transport (GO:0015986)2.18175206

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.57478187
2GBX2_23144817_ChIP-Seq_PC3_Human3.79745486
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.59299202
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.15770592
5TAF15_26573619_Chip-Seq_HEK293_Human2.88463663
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.74472723
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.67670687
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.61205543
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.58219815
10* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.46416500
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.43747502
12SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.40142785
13VDR_22108803_ChIP-Seq_LS180_Human2.32415037
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.28927732
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.27607271
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.27085070
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.19921251
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.19236618
19EZH2_18974828_ChIP-Seq_MESCs_Mouse2.15826117
20RNF2_18974828_ChIP-Seq_MESCs_Mouse2.15826117
21JARID2_20075857_ChIP-Seq_MESCs_Mouse2.14859887
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.08640354
23EST1_17652178_ChIP-ChIP_JURKAT_Human2.07183062
24ZNF274_21170338_ChIP-Seq_K562_Hela2.04737177
25EWS_26573619_Chip-Seq_HEK293_Human1.99017767
26GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.98182505
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96384181
28E2F7_22180533_ChIP-Seq_HELA_Human1.95229770
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.94376333
30P300_19829295_ChIP-Seq_ESCs_Human1.92974025
31HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.90766497
32SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.90146425
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.89174157
34MTF2_20144788_ChIP-Seq_MESCs_Mouse1.88195218
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.86680918
36SALL1_21062744_ChIP-ChIP_HESCs_Human1.86363610
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.84451660
38RNF2_27304074_Chip-Seq_ESCs_Mouse1.82408134
39IGF1R_20145208_ChIP-Seq_DFB_Human1.81179617
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.80411290
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.79600001
42E2F4_17652178_ChIP-ChIP_JURKAT_Human1.76848322
43CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74970402
44SUZ12_27294783_Chip-Seq_ESCs_Mouse1.74791315
45RNF2_27304074_Chip-Seq_NSC_Mouse1.73140020
46SMAD4_21799915_ChIP-Seq_A2780_Human1.68822663
47REST_21632747_ChIP-Seq_MESCs_Mouse1.68593436
48PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.68060218
49CDX2_19796622_ChIP-Seq_MESCs_Mouse1.64186604
50GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.59244782
51PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.59019739
52ELK1_19687146_ChIP-ChIP_HELA_Human1.58275284
53SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56306117
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.55756371
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.52595104
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.51928731
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50842969
58RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.50573294
59CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50138286
60NANOG_18555785_Chip-Seq_ESCs_Mouse1.48374156
61NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.46203273
62FUS_26573619_Chip-Seq_HEK293_Human1.45634907
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.45212914
64EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.44976038
65TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.44067547
66CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.43716727
67SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42902993
68IKZF1_21737484_ChIP-ChIP_HCT116_Human1.42747859
69SUZ12_18555785_Chip-Seq_ESCs_Mouse1.42700768
70BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.42626541
71ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.42335760
72ER_23166858_ChIP-Seq_MCF-7_Human1.41437028
73VDR_23849224_ChIP-Seq_CD4+_Human1.41109660
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.40664689
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38389919
76TP53_22573176_ChIP-Seq_HFKS_Human1.37652476
77CMYC_18555785_Chip-Seq_ESCs_Mouse1.36530458
78AR_21572438_ChIP-Seq_LNCaP_Human1.36459346
79E2F1_18555785_Chip-Seq_ESCs_Mouse1.36204177
80P53_22387025_ChIP-Seq_ESCs_Mouse1.34390415
81UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33629320
82RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.31609096
83NFE2_27457419_Chip-Seq_LIVER_Mouse1.30912827
84CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30819962
85TAL1_26923725_Chip-Seq_HPCs_Mouse1.30027538
86P300_18555785_Chip-Seq_ESCs_Mouse1.29982792
87STAT3_18555785_Chip-Seq_ESCs_Mouse1.29605989
88EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.29553154
89VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.28337018
90FOXP3_21729870_ChIP-Seq_TREG_Human1.27590437
91CREB1_15753290_ChIP-ChIP_HEK293T_Human1.27494972
92FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.26637427
93E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.25052075
94KDM2B_26808549_Chip-Seq_REH_Human1.24336120
95* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23764490
96SOX2_18555785_Chip-Seq_ESCs_Mouse1.23591139
97CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22980717
98SMAD_19615063_ChIP-ChIP_OVARY_Human1.22472383
99SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21519824
100EZH2_27294783_Chip-Seq_NPCs_Mouse1.21361270
101HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21182410
102HTT_18923047_ChIP-ChIP_STHdh_Human1.21124013
103MYC_18940864_ChIP-ChIP_HL60_Human1.20759281
104RUNX1_27457419_Chip-Seq_LIVER_Mouse1.20754072
105NMYC_18555785_Chip-Seq_ESCs_Mouse1.19427524
106KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.18854773
107STAT3_23295773_ChIP-Seq_U87_Human1.18723030
108ETS1_20019798_ChIP-Seq_JURKAT_Human1.18423931
109CBP_20019798_ChIP-Seq_JUKART_Human1.16554293
110IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16554293
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16355361
112RUNX2_22187159_ChIP-Seq_PCA_Human1.15781083
113AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15238384
114PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13949597
115DROSHA_22980978_ChIP-Seq_HELA_Human1.13642683
116PRDM14_20953172_ChIP-Seq_ESCs_Human1.12973723
117REST_18959480_ChIP-ChIP_MESCs_Mouse1.12605574
118NANOG_19829295_ChIP-Seq_ESCs_Human1.12476438
119SOX2_19829295_ChIP-Seq_ESCs_Human1.12476438
120PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11471138
121GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10412699
122KLF4_18555785_Chip-Seq_ESCs_Mouse1.10001318
123FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.09837465
124EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.09492041
125AR_25329375_ChIP-Seq_VCAP_Human1.08434836
126SMAD1_18555785_Chip-Seq_ESCs_Mouse1.07539239
127TCF4_23295773_ChIP-Seq_U87_Human1.07479391
128JUN_21703547_ChIP-Seq_K562_Human1.07026209
129TP63_19390658_ChIP-ChIP_HaCaT_Human1.05850936
130OCT4_18555785_Chip-Seq_ESCs_Mouse1.04012341
131TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03692813
132NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03198747
133AUTS2_25519132_ChIP-Seq_293T-REX_Human1.02129081
134CTCF_18555785_Chip-Seq_ESCs_Mouse1.02008483
135PU1_27457419_Chip-Seq_LIVER_Mouse1.01864212
136TCF4_22108803_ChIP-Seq_LS180_Human1.01479498
137NR3C1_23031785_ChIP-Seq_PC12_Mouse0.99769288
138EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99173610
139ZFX_18555785_Chip-Seq_ESCs_Mouse0.99077926
140AHR_22903824_ChIP-Seq_MCF-7_Human0.98079919
141ESRRB_18555785_Chip-Seq_ESCs_Mouse0.97628218
142CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.97496308
143PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96850833
144PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.96818406
145POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95743382

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation4.26424888
2MP0002735_abnormal_chemical_nociception3.60286531
3MP0003880_abnormal_central_pattern3.34251174
4MP0001968_abnormal_touch/_nociception3.21253722
5MP0002736_abnormal_nociception_after3.16147933
6MP0006276_abnormal_autonomic_nervous3.15819386
7MP0004270_analgesia3.15337531
8MP0001188_hyperpigmentation2.92650676
9MP0009780_abnormal_chondrocyte_physiolo2.81946741
10MP0004859_abnormal_synaptic_plasticity2.77330513
11MP0002734_abnormal_mechanical_nocicepti2.52096335
12MP0008057_abnormal_DNA_replication2.50840996
13MP0002272_abnormal_nervous_system2.49652192
14MP0009745_abnormal_behavioral_response2.45143940
15MP0005171_absent_coat_pigmentation2.41530218
16MP0001486_abnormal_startle_reflex2.37793884
17MP0001529_abnormal_vocalization2.37370672
18MP0003635_abnormal_synaptic_transmissio2.33671380
19MP0001905_abnormal_dopamine_level2.29918306
20MP0008058_abnormal_DNA_repair2.29028455
21MP0002837_dystrophic_cardiac_calcinosis2.26369718
22MP0001970_abnormal_pain_threshold2.24938123
23MP0001986_abnormal_taste_sensitivity2.24064639
24MP0002064_seizures2.18701076
25MP0009046_muscle_twitch2.14139021
26MP0002638_abnormal_pupillary_reflex2.12587127
27MP0002733_abnormal_thermal_nociception2.11380245
28MP0003718_maternal_effect2.07048273
29MP0005645_abnormal_hypothalamus_physiol1.98561452
30MP0003890_abnormal_embryonic-extraembry1.97439228
31MP0002572_abnormal_emotion/affect_behav1.97342582
32MP0000372_irregular_coat_pigmentation1.97210838
33MP0010386_abnormal_urinary_bladder1.93475050
34MP0001984_abnormal_olfaction1.90825862
35MP0002063_abnormal_learning/memory/cond1.90510152
36MP0004742_abnormal_vestibular_system1.89468557
37MP0000015_abnormal_ear_pigmentation1.86252771
38MP0000778_abnormal_nervous_system1.83741061
39MP0002067_abnormal_sensory_capabilities1.82867783
40MP0004142_abnormal_muscle_tone1.82597146
41MP0005409_darkened_coat_color1.79840815
42MP0005499_abnormal_olfactory_system1.78194316
43MP0005394_taste/olfaction_phenotype1.78194316
44MP0002184_abnormal_innervation1.77232864
45MP0000427_abnormal_hair_cycle1.75077739
46MP0005423_abnormal_somatic_nervous1.75059000
47MP0010094_abnormal_chromosome_stability1.73990482
48MP0000920_abnormal_myelination1.71890503
49MP0002653_abnormal_ependyma_morphology1.71674689
50MP0008789_abnormal_olfactory_epithelium1.70366909
51MP0001440_abnormal_grooming_behavior1.68178323
52MP0008872_abnormal_physiological_respon1.59497695
53MP0003136_yellow_coat_color1.54977775
54MP0002557_abnormal_social/conspecific_i1.52445494
55MP0001963_abnormal_hearing_physiology1.50693295
56MP0001485_abnormal_pinna_reflex1.50121346
57MP0002822_catalepsy1.48606438
58MP0001502_abnormal_circadian_rhythm1.46668407
59MP0003121_genomic_imprinting1.46404636
60MP0005410_abnormal_fertilization1.44248164
61MP0002277_abnormal_respiratory_mucosa1.43961713
62MP0000569_abnormal_digit_pigmentation1.42119108
63MP0005551_abnormal_eye_electrophysiolog1.39877516
64MP0008260_abnormal_autophagy1.39762033
65MP0005174_abnormal_tail_pigmentation1.32634822
66MP0002882_abnormal_neuron_morphology1.31638151
67MP0002876_abnormal_thyroid_physiology1.31048430
68MP0000955_abnormal_spinal_cord1.30267969
69MP0005646_abnormal_pituitary_gland1.27381371
70MP0002229_neurodegeneration1.25643902
71MP0002752_abnormal_somatic_nervous1.25336667
72MP0001501_abnormal_sleep_pattern1.25093392
73MP0003879_abnormal_hair_cell1.25051620
74MP0005386_behavior/neurological_phenoty1.21862249
75MP0004924_abnormal_behavior1.21862249
76MP0001944_abnormal_pancreas_morphology1.21817425
77MP0002102_abnormal_ear_morphology1.19196103
78MP0002751_abnormal_autonomic_nervous1.16405666
79MP0009379_abnormal_foot_pigmentation1.15704836
80MP0004043_abnormal_pH_regulation1.12912696
81MP0004381_abnormal_hair_follicle1.12414085
82MP0002909_abnormal_adrenal_gland1.12281107
83MP0003787_abnormal_imprinting1.11483807
84MP0000026_abnormal_inner_ear1.10450631
85MP0006292_abnormal_olfactory_placode1.09774210
86MP0001929_abnormal_gametogenesis1.09612306
87MP0003786_premature_aging1.08230707
88MP0003195_calcinosis1.08138362
89MP0002210_abnormal_sex_determination1.07272459
90MP0008995_early_reproductive_senescence1.07066563
91MP0002928_abnormal_bile_duct1.04178184
92MP0002066_abnormal_motor_capabilities/c1.03437559
93MP0002160_abnormal_reproductive_system1.02152313
94MP0004885_abnormal_endolymph0.99753286
95MP0003693_abnormal_embryo_hatching0.98495929
96MP0003634_abnormal_glial_cell0.97795087
97MP0004811_abnormal_neuron_physiology0.97007262
98MP0006036_abnormal_mitochondrial_physio0.96579010
99MP0008569_lethality_at_weaning0.94884893
100MP0000538_abnormal_urinary_bladder0.94623123
101MP0000653_abnormal_sex_gland0.93899483
102MP0004133_heterotaxia0.92921262
103MP0001324_abnormal_eye_pigmentation0.91019392
104MP0005253_abnormal_eye_physiology0.89888983
105MP0002938_white_spotting0.89876314
106MP0000013_abnormal_adipose_tissue0.85774886
107MP0010234_abnormal_vibrissa_follicle0.84199407
108MP0009697_abnormal_copulation0.83965643
109MP0005451_abnormal_body_composition0.82632802
110MP0004957_abnormal_blastocyst_morpholog0.81952401
111MP0001145_abnormal_male_reproductive0.81109951
112MP0003329_amyloid_beta_deposits0.81102057
113MP0002233_abnormal_nose_morphology0.79690150
114MP0003631_nervous_system_phenotype0.79263175
115MP0003633_abnormal_nervous_system0.78890025
116MP0003119_abnormal_digestive_system0.78857152
117MP0003111_abnormal_nucleus_morphology0.78742850
118MP0003077_abnormal_cell_cycle0.78272613
119MP0006035_abnormal_mitochondrial_morpho0.78043141
120MP0004858_abnormal_nervous_system0.77971195
121MP0005075_abnormal_melanosome_morpholog0.75347779
122MP0005084_abnormal_gallbladder_morpholo0.75170583
123MP0002161_abnormal_fertility/fecundity0.74921283
124MP0003186_abnormal_redox_activity0.74111049
125MP0001293_anophthalmia0.73995947
126MP0006072_abnormal_retinal_apoptosis0.73482230
127MP0000631_abnormal_neuroendocrine_gland0.72513333
128MP0000566_synostosis0.72171566
129MP0001542_abnormal_bone_strength0.70853307
130MP0002152_abnormal_brain_morphology0.70619369
131MP0001348_abnormal_lacrimal_gland0.70207651
132MP0005379_endocrine/exocrine_gland_phen0.68043936
133MP0003122_maternal_imprinting0.65779409
134MP0000681_abnormal_thyroid_gland0.60219299
135MP0001177_atelectasis0.59692880
136MP0002095_abnormal_skin_pigmentation0.58638391
137MP0004147_increased_porphyrin_level0.58476469
138MP0003698_abnormal_male_reproductive0.58476255
139MP0003632_abnormal_nervous_system0.55006126
140MP0002163_abnormal_gland_morphology0.54456500

Predicted human phenotypes

RankGene SetZ-score
1Hypothermia (HP:0002045)4.99947454
2Focal motor seizures (HP:0011153)4.69568408
3Febrile seizures (HP:0002373)4.47231102
4Myokymia (HP:0002411)4.39085369
5Abnormality of the labia minora (HP:0012880)3.75341558
6Retinal dysplasia (HP:0007973)3.50885376
7Degeneration of the lateral corticospinal tracts (HP:0002314)3.50679802
8Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.50679802
9Medial flaring of the eyebrow (HP:0010747)3.34734754
10Aplasia/Hypoplasia of the fovea (HP:0008060)3.33754792
11Hypoplasia of the fovea (HP:0007750)3.33754792
12Focal seizures (HP:0007359)3.24743282
13Acute necrotizing encephalopathy (HP:0006965)3.20953767
14Atonic seizures (HP:0010819)3.19424059
15Intestinal atresia (HP:0011100)3.17501759
16Gait imbalance (HP:0002141)3.03683161
17Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.02193713
18Abnormal ciliary motility (HP:0012262)2.94263230
19Abnormality of the corticospinal tract (HP:0002492)2.90065728
20Progressive macrocephaly (HP:0004481)2.88455266
21Abnormality of the fovea (HP:0000493)2.85569508
22Nephrogenic diabetes insipidus (HP:0009806)2.84542493
23Congenital primary aphakia (HP:0007707)2.83182735
24Abnormal respiratory motile cilium physiology (HP:0012261)2.76226837
25Hyperinsulinemic hypoglycemia (HP:0000825)2.76104258
26Epileptic encephalopathy (HP:0200134)2.72572016
27Sensory axonal neuropathy (HP:0003390)2.70554354
28Dialeptic seizures (HP:0011146)2.70153105
29Genital tract atresia (HP:0001827)2.69629567
30Congenital stationary night blindness (HP:0007642)2.69612718
31Limb dystonia (HP:0002451)2.67684076
32Abnormal mitochondria in muscle tissue (HP:0008316)2.66154264
33Volvulus (HP:0002580)2.65820188
34Dynein arm defect of respiratory motile cilia (HP:0012255)2.64479977
35Absent/shortened dynein arms (HP:0200106)2.64479977
36Abnormal respiratory motile cilium morphology (HP:0005938)2.63654841
37Abnormal respiratory epithelium morphology (HP:0012253)2.63654841
38Large for gestational age (HP:0001520)2.62846119
39Vaginal atresia (HP:0000148)2.60909347
40Mitochondrial inheritance (HP:0001427)2.60189079
41Neurofibrillary tangles (HP:0002185)2.58412943
42Progressive cerebellar ataxia (HP:0002073)2.58191072
43Ulnar claw (HP:0001178)2.55201249
44Supranuclear gaze palsy (HP:0000605)2.54822074
45Optic disc pallor (HP:0000543)2.53795052
46Pancreatic islet-cell hyperplasia (HP:0004510)2.52265278
47Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.49258279
48Absence seizures (HP:0002121)2.47859548
49Gastrointestinal atresia (HP:0002589)2.46484469
50Abnormal hair whorl (HP:0010721)2.41165814
51Generalized tonic-clonic seizures (HP:0002069)2.40441970
52Limb hypertonia (HP:0002509)2.39075598
53Hyperglycemia (HP:0003074)2.38523527
54Acute encephalopathy (HP:0006846)2.37755031
55Colon cancer (HP:0003003)2.37714655
56Aplasia/Hypoplasia of the macula (HP:0008059)2.35390843
57Parakeratosis (HP:0001036)2.33004471
583-Methylglutaconic aciduria (HP:0003535)2.32253358
59Renal Fanconi syndrome (HP:0001994)2.31117220
60Pancreatic cysts (HP:0001737)2.31006806
61Leukodystrophy (HP:0002415)2.26471363
62Patchy hypopigmentation of hair (HP:0011365)2.24587904
63Ketoacidosis (HP:0001993)2.23534487
64Anosmia (HP:0000458)2.20319289
65Abnormality of aromatic amino acid family metabolism (HP:0004338)2.19388130
66Chromsome breakage (HP:0040012)2.18772138
67Peripheral hypomyelination (HP:0007182)2.18463994
68White forelock (HP:0002211)2.16054123
69Aplasia/Hypoplasia affecting the retina (HP:0008061)2.15750208
70Methylmalonic aciduria (HP:0012120)2.15156273
71Postural tremor (HP:0002174)2.14621410
72Hepatic necrosis (HP:0002605)2.14578732
73Hyperglycinemia (HP:0002154)2.14351153
74Short tibia (HP:0005736)2.14175633
75Aplasia/Hypoplasia of the uvula (HP:0010293)2.12136603
76Congenital sensorineural hearing impairment (HP:0008527)2.11898192
77Prominent metopic ridge (HP:0005487)2.11644000
78Lipid accumulation in hepatocytes (HP:0006561)2.10956222
79Hyperventilation (HP:0002883)2.09857249
80Aplasia/Hypoplasia of the lens (HP:0008063)2.09791120
81Increased hepatocellular lipid droplets (HP:0006565)2.09260202
82Failure to thrive in infancy (HP:0001531)2.08417757
83Ankle clonus (HP:0011448)2.06052038
84Abnormality of the metopic suture (HP:0005556)2.05190867
85Molar tooth sign on MRI (HP:0002419)2.04602542
86Abnormality of midbrain morphology (HP:0002418)2.04602542
87Abnormality of vitamin B metabolism (HP:0004340)2.03568678
88Aplasia/Hypoplasia of the tibia (HP:0005772)2.02075040
89Segmental peripheral demyelination/remyelination (HP:0003481)1.99362205
90Gaze-evoked nystagmus (HP:0000640)1.99302441
91Poor coordination (HP:0002370)1.98636224
92Submucous cleft hard palate (HP:0000176)1.98127350
93Abnormality of chromosome stability (HP:0003220)1.96985315
94Abnormal rod and cone electroretinograms (HP:0008323)1.96427823
95Blue irides (HP:0000635)1.95420155
96Autoamputation (HP:0001218)1.95099026
97Type II lissencephaly (HP:0007260)1.94809466
98Septo-optic dysplasia (HP:0100842)1.94006314
99Muscular hypotonia of the trunk (HP:0008936)1.93228903
100Epileptiform EEG discharges (HP:0011182)1.92332779
101Hepatocellular necrosis (HP:0001404)1.92258560
102Rhinitis (HP:0012384)1.92217278
103Decreased central vision (HP:0007663)1.92113884
104EEG with generalized epileptiform discharges (HP:0011198)1.91707238
105Increased CSF lactate (HP:0002490)1.91424683
106Absent speech (HP:0001344)1.91315000
107Hypsarrhythmia (HP:0002521)1.89217536
108Retinal atrophy (HP:0001105)1.87930773
109Bradycardia (HP:0001662)1.87497948
110Hypokinesia (HP:0002375)1.87017095
111Amblyopia (HP:0000646)1.86994190
112Broad-based gait (HP:0002136)1.86988874
113Thyroid-stimulating hormone excess (HP:0002925)1.86316019
114Poor suck (HP:0002033)1.86301160
115Specific learning disability (HP:0001328)1.86174222
116Pancreatic fibrosis (HP:0100732)1.86050440
117Abnormality of renal resorption (HP:0011038)1.85804999
118Unilateral renal agenesis (HP:0000122)1.85568667
119Chromosomal breakage induced by crosslinking agents (HP:0003221)1.84334911
120Visual hallucinations (HP:0002367)1.83447255
121Hypophosphatemic rickets (HP:0004912)1.83010397
122Absent rod-and cone-mediated responses on ERG (HP:0007688)1.82710924
123Dysmetria (HP:0001310)1.82707083
124Esotropia (HP:0000565)1.82078883
125Abnormality of urine glucose concentration (HP:0011016)1.81526590
126Glycosuria (HP:0003076)1.81526590
127Scanning speech (HP:0002168)1.81403766
128Median cleft lip (HP:0000161)1.81364945
129Facial cleft (HP:0002006)1.79249735
130Dysdiadochokinesis (HP:0002075)1.77242603
131Nephronophthisis (HP:0000090)1.76815906
132J-shaped sella turcica (HP:0002680)1.75741107
133Aqueductal stenosis (HP:0002410)1.75628154
134Action tremor (HP:0002345)1.75270980
135Abnormality of the pancreatic islet cells (HP:0006476)1.72125052
136Abnormality of endocrine pancreas physiology (HP:0012093)1.72125052
137Oligodactyly (hands) (HP:0001180)1.71820609
138Insidious onset (HP:0003587)1.70670225
139Termporal pattern (HP:0011008)1.70670225
140Spastic gait (HP:0002064)1.70578326
141Morphological abnormality of the inner ear (HP:0011390)1.69120819
142Hypoglycemic coma (HP:0001325)1.68755046
143Cerebral inclusion bodies (HP:0100314)1.68116524
144Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.67779379
145Labial hypoplasia (HP:0000066)1.67554715
146Attenuation of retinal blood vessels (HP:0007843)1.67400864
147Xerostomia (HP:0000217)1.67282164
148Lissencephaly (HP:0001339)1.66813617
149Hypomagnesemia (HP:0002917)1.66733126
150Broad foot (HP:0001769)1.66164336
151Abnormality of abdominal situs (HP:0011620)1.65780918
152Abdominal situs inversus (HP:0003363)1.65780918
153Onion bulb formation (HP:0003383)1.65473333
154Abnormality of the renal medulla (HP:0100957)1.64415036
155Duplicated collecting system (HP:0000081)1.63979509
156Increased serum lactate (HP:0002151)1.63237393
157Generalized hypopigmentation of hair (HP:0011358)1.62694247
158Optic nerve hypoplasia (HP:0000609)1.62532637
159Abnormality of alanine metabolism (HP:0010916)1.62495133
160Hyperalaninemia (HP:0003348)1.62495133
161Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.62495133
162Pheochromocytoma (HP:0002666)1.61596873
163Bifid tongue (HP:0010297)1.61428853
164Cerebral edema (HP:0002181)1.61186252
165Methylmalonic acidemia (HP:0002912)1.60897649
166Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.60623146
167Decreased testicular size (HP:0008734)1.60243880
168Meckel diverticulum (HP:0002245)1.60081673
169Metaphyseal dysplasia (HP:0100255)1.59434942
170Choroideremia (HP:0001139)1.59108839

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.98762931
2STK393.18941517
3MAP2K73.04492936
4MAP4K22.65423425
5FRK2.50284705
6TRIM282.22019718
7OXSR12.17886690
8GRK52.14843494
9MAP3K122.10216255
10EIF2AK12.06638621
11BUB12.06388620
12WNK32.05561138
13NTRK32.02242591
14FGFR21.93724757
15EIF2AK31.93123170
16MAP3K41.85722650
17BMPR21.85346805
18MAPKAPK51.84369503
19WEE11.82567776
20WNK41.79915735
21TNIK1.78479032
22PNCK1.75271936
23MARK11.74780038
24TTK1.69310586
25IRAK11.64182362
26MST41.61356460
27ARAF1.60102696
28NUAK11.58267469
29MAPK131.57305405
30LATS11.53379928
31CDC71.53252812
32MINK11.51433631
33TAF11.48482535
34MKNK21.46028409
35SGK4941.45077873
36SGK2231.45077873
37PLK21.43517300
38GRK71.42003449
39BCR1.41190860
40RIPK41.38565014
41DAPK11.36735602
42IRAK21.36285466
43NME11.35940755
44NTRK11.33590159
45PRPF4B1.33182287
46PLK31.31740543
47BMPR1B1.22568087
48CAMK2B1.22487327
49PBK1.19896499
50PKN11.19101734
51SIK31.16379037
52CSNK1G31.14516320
53UHMK11.13651924
54CAMK2D1.11580309
55ZAK1.11165279
56ADRBK21.09899595
57CDK191.08895724
58PRKCE1.05964311
59GRK11.05282094
60NEK61.05021933
61PHKG11.04688939
62PHKG21.04688939
63TXK1.03555723
64RPS6KA41.02708333
65PLK11.02351303
66BRSK21.01412445
67CAMK2A1.01379725
68CSNK1A1L0.96570952
69CSNK1G20.95179398
70LIMK10.93543146
71WNK10.92446867
72PINK10.91836096
73AKT30.90761721
74IRAK30.90720078
75CAMK2G0.89802085
76STK30.89546893
77EPHB10.89053237
78MAP2K40.89023314
79STK160.88533480
80PASK0.88318142
81ERBB30.87288923
82MKNK10.87267440
83IRAK40.87202160
84CDK50.85496536
85EPHA40.83706041
86TSSK60.83084780
87DYRK20.82977495
88PAK60.82759363
89STK38L0.82666033
90FES0.81146254
91YES10.80579407
92ACVR1B0.76968836
93EPHA30.76569217
94CHEK20.74754494
95DAPK20.74461860
96BRAF0.73806165
97NTRK20.73210715
98MUSK0.73052331
99NLK0.71719243
100CSNK1G10.70691594
101FER0.70440721
102PAK30.70199479
103SGK20.66660384
104ATM0.65239932
105FGR0.63355309
106MARK30.63171715
107EIF2AK20.62342001
108PRKCI0.60436310
109ATR0.59910607
110TNK20.59873919
111RPS6KA50.56393544
112PRKCG0.56370845
113CDK30.55734480
114DYRK30.55640333
115CAMKK20.54788009
116VRK10.52815002
117ADRBK10.52673303
118CSNK1A10.51725300
119PLK40.51295644
120PRKCQ0.50384988
121MAP3K130.49810601
122TAOK30.49262163
123MATK0.48400886
124TEC0.47473375
125ROCK20.47336115
126DAPK30.47178709
127PRKACA0.46907131
128MAPK150.46830399
129CSNK2A20.46401687
130DYRK1A0.45344767
131LMTK20.45106961
132CSNK1D0.44916630
133PRKG10.44849844
134TRPM70.44331400
135CSNK1E0.44152169
136CAMK10.43885321
137PIM20.43429354
138CDK140.43301642
139INSRR0.43156061
140PRKDC0.42129980
141MARK20.41642570
142STK240.40953778
143PRKD30.40654356
144STK110.40424017
145CDK180.39380197
146MAP3K90.38977163

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.40785530
2Oxidative phosphorylation_Homo sapiens_hsa001903.19634092
3Phototransduction_Homo sapiens_hsa047442.86768041
4Basal transcription factors_Homo sapiens_hsa030222.81612307
5Nicotine addiction_Homo sapiens_hsa050332.73509321
6Folate biosynthesis_Homo sapiens_hsa007902.67050166
7Mismatch repair_Homo sapiens_hsa034302.62009716
8Synaptic vesicle cycle_Homo sapiens_hsa047212.61117352
9Collecting duct acid secretion_Homo sapiens_hsa049662.50693612
10Parkinsons disease_Homo sapiens_hsa050122.50232169
11Olfactory transduction_Homo sapiens_hsa047402.42974112
12Homologous recombination_Homo sapiens_hsa034402.37758502
13Taste transduction_Homo sapiens_hsa047422.21285827
14Alzheimers disease_Homo sapiens_hsa050102.20567302
15Serotonergic synapse_Homo sapiens_hsa047262.14952166
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.14595548
17SNARE interactions in vesicular transport_Homo sapiens_hsa041302.12247071
18Morphine addiction_Homo sapiens_hsa050322.07191603
19Steroid biosynthesis_Homo sapiens_hsa001002.06627581
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.96281998
21Glutamatergic synapse_Homo sapiens_hsa047241.92447831
22GABAergic synapse_Homo sapiens_hsa047271.86609473
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.83810692
24Huntingtons disease_Homo sapiens_hsa050161.79966114
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.79877208
26Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.76373545
27Circadian entrainment_Homo sapiens_hsa047131.73285717
28Selenocompound metabolism_Homo sapiens_hsa004501.73193507
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.67855140
30Fanconi anemia pathway_Homo sapiens_hsa034601.65643894
31Non-homologous end-joining_Homo sapiens_hsa034501.65367614
32RNA degradation_Homo sapiens_hsa030181.65104539
33Ribosome_Homo sapiens_hsa030101.63328528
34Proteasome_Homo sapiens_hsa030501.57332783
35Dopaminergic synapse_Homo sapiens_hsa047281.56921548
36Amphetamine addiction_Homo sapiens_hsa050311.53459537
37RNA polymerase_Homo sapiens_hsa030201.47525915
38Fatty acid elongation_Homo sapiens_hsa000621.46914994
39Ether lipid metabolism_Homo sapiens_hsa005651.43738196
40Nucleotide excision repair_Homo sapiens_hsa034201.43697341
41DNA replication_Homo sapiens_hsa030301.41073056
42Cholinergic synapse_Homo sapiens_hsa047251.40837718
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.40127443
44Propanoate metabolism_Homo sapiens_hsa006401.39650777
45RNA transport_Homo sapiens_hsa030131.37543730
46Cardiac muscle contraction_Homo sapiens_hsa042601.36825875
47Caffeine metabolism_Homo sapiens_hsa002321.36233771
48Protein export_Homo sapiens_hsa030601.35730499
49Long-term potentiation_Homo sapiens_hsa047201.35490375
50Vibrio cholerae infection_Homo sapiens_hsa051101.34222019
51Circadian rhythm_Homo sapiens_hsa047101.32608390
52Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.30178944
53Cocaine addiction_Homo sapiens_hsa050301.30136149
54Rheumatoid arthritis_Homo sapiens_hsa053231.29824210
55Salivary secretion_Homo sapiens_hsa049701.28605843
56Sphingolipid metabolism_Homo sapiens_hsa006001.26975287
57Long-term depression_Homo sapiens_hsa047301.26751186
58Insulin secretion_Homo sapiens_hsa049111.24569526
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.24077949
60Oocyte meiosis_Homo sapiens_hsa041141.22749613
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.20082220
62Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.19132866
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.19029265
64Butanoate metabolism_Homo sapiens_hsa006501.15145346
65Renin secretion_Homo sapiens_hsa049241.12948779
66Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.12477278
67Nitrogen metabolism_Homo sapiens_hsa009101.11255349
68Axon guidance_Homo sapiens_hsa043601.10505815
69Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10093546
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.09819631
71Arachidonic acid metabolism_Homo sapiens_hsa005901.08119446
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.06920352
73Base excision repair_Homo sapiens_hsa034101.01825417
74Calcium signaling pathway_Homo sapiens_hsa040201.01437671
75Glutathione metabolism_Homo sapiens_hsa004801.00536901
76Autoimmune thyroid disease_Homo sapiens_hsa053201.00348629
77Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.94844983
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.94498189
79Phagosome_Homo sapiens_hsa041450.92269309
80Regulation of autophagy_Homo sapiens_hsa041400.91016891
81Cell cycle_Homo sapiens_hsa041100.90766211
82Gastric acid secretion_Homo sapiens_hsa049710.86677479
83Histidine metabolism_Homo sapiens_hsa003400.82447070
84Sulfur metabolism_Homo sapiens_hsa009200.77118645
85Aldosterone synthesis and secretion_Homo sapiens_hsa049250.77059774
86Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.76224005
87One carbon pool by folate_Homo sapiens_hsa006700.75666565
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.71947993
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.71119724
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.69194956
91Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.67968035
92Allograft rejection_Homo sapiens_hsa053300.66678511
93Cysteine and methionine metabolism_Homo sapiens_hsa002700.65255787
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.64958533
95Chemical carcinogenesis_Homo sapiens_hsa052040.64879725
96Oxytocin signaling pathway_Homo sapiens_hsa049210.64599757
97Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.64476237
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.64085459
99cAMP signaling pathway_Homo sapiens_hsa040240.63837606
100Vitamin B6 metabolism_Homo sapiens_hsa007500.63236892
101Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62722159
102Spliceosome_Homo sapiens_hsa030400.61958425
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.61484648
104Linoleic acid metabolism_Homo sapiens_hsa005910.59794155
105GnRH signaling pathway_Homo sapiens_hsa049120.59703907
106Gap junction_Homo sapiens_hsa045400.59634208
107Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58988189
108Pyrimidine metabolism_Homo sapiens_hsa002400.58849588
109Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.58848780
110Alcoholism_Homo sapiens_hsa050340.57579076
111Ovarian steroidogenesis_Homo sapiens_hsa049130.57501920
112Ras signaling pathway_Homo sapiens_hsa040140.57216413
113Melanogenesis_Homo sapiens_hsa049160.52880594
114Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.52650145
115Graft-versus-host disease_Homo sapiens_hsa053320.51536805
116Dorso-ventral axis formation_Homo sapiens_hsa043200.50877579
117African trypanosomiasis_Homo sapiens_hsa051430.50319186
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.49796913
119Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.49126367
120Hedgehog signaling pathway_Homo sapiens_hsa043400.49077210
121Tryptophan metabolism_Homo sapiens_hsa003800.47058899
122Pyruvate metabolism_Homo sapiens_hsa006200.46378720
123Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43126001
124Pancreatic secretion_Homo sapiens_hsa049720.42431482
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.42237226
126Type II diabetes mellitus_Homo sapiens_hsa049300.41524341
127Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.41046113
128ErbB signaling pathway_Homo sapiens_hsa040120.40785724
129cGMP-PKG signaling pathway_Homo sapiens_hsa040220.39956723
130Wnt signaling pathway_Homo sapiens_hsa043100.39378300
131Hippo signaling pathway_Homo sapiens_hsa043900.38990440
132Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38937318
133Asthma_Homo sapiens_hsa053100.38464341
134Phospholipase D signaling pathway_Homo sapiens_hsa040720.37477279
135mRNA surveillance pathway_Homo sapiens_hsa030150.37418584
136Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.36566539
137Type I diabetes mellitus_Homo sapiens_hsa049400.35073314
138MAPK signaling pathway_Homo sapiens_hsa040100.34035011
139Intestinal immune network for IgA production_Homo sapiens_hsa046720.33084720
140Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.33011618
141Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30250795
142Chemokine signaling pathway_Homo sapiens_hsa040620.29819128
143Estrogen signaling pathway_Homo sapiens_hsa049150.28718968
144Metabolic pathways_Homo sapiens_hsa011000.28554291
145Mineral absorption_Homo sapiens_hsa049780.28478567
146Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.26174773
147Thyroid hormone synthesis_Homo sapiens_hsa049180.25454625
148Melanoma_Homo sapiens_hsa052180.25103482
149Choline metabolism in cancer_Homo sapiens_hsa052310.22469942
150Tyrosine metabolism_Homo sapiens_hsa003500.22131123
151Purine metabolism_Homo sapiens_hsa002300.21444332

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