RBM15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)5.15657453
2nuclear pore complex assembly (GO:0051292)4.88968153
3kinetochore organization (GO:0051383)4.38315810
4mitotic metaphase plate congression (GO:0007080)4.17107051
5regulation of centriole replication (GO:0046599)4.14435643
6meiotic chromosome segregation (GO:0045132)4.14319950
7CENP-A containing nucleosome assembly (GO:0034080)4.12866762
8chromatin remodeling at centromere (GO:0031055)4.11036548
9telomere maintenance via semi-conservative replication (GO:0032201)4.01004741
10pore complex assembly (GO:0046931)3.97635071
11regulation of RNA export from nucleus (GO:0046831)3.93904616
12telomere maintenance via recombination (GO:0000722)3.91838245
13attachment of spindle microtubules to kinetochore (GO:0008608)3.91218394
14DNA strand elongation involved in DNA replication (GO:0006271)3.89748147
15mitotic recombination (GO:0006312)3.83748594
16pre-miRNA processing (GO:0031054)3.83294949
17protein localization to chromosome, centromeric region (GO:0071459)3.83191364
18metaphase plate congression (GO:0051310)3.81655110
19protein localization to kinetochore (GO:0034501)3.80126956
20DNA strand elongation (GO:0022616)3.77288166
21mitotic chromosome condensation (GO:0007076)3.76506674
22mitotic sister chromatid cohesion (GO:0007064)3.74472445
23kinetochore assembly (GO:0051382)3.70666675
24monoubiquitinated protein deubiquitination (GO:0035520)3.66159402
25DNA replication initiation (GO:0006270)3.64304055
26chromatin assembly (GO:0031497)3.63914563
27positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.63190491
28positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.63190491
29positive regulation of mitotic sister chromatid separation (GO:1901970)3.63190491
30DNA replication-independent nucleosome assembly (GO:0006336)3.60194187
31DNA replication-independent nucleosome organization (GO:0034724)3.60194187
32establishment of chromosome localization (GO:0051303)3.56164105
33negative regulation of DNA repair (GO:0045738)3.55928206
34non-recombinational repair (GO:0000726)3.53304188
35double-strand break repair via nonhomologous end joining (GO:0006303)3.53304188
36V(D)J recombination (GO:0033151)3.51403885
37regulation of DNA endoreduplication (GO:0032875)3.50716312
38mitotic nuclear envelope disassembly (GO:0007077)3.49123199
39IMP biosynthetic process (GO:0006188)3.44884815
40DNA replication checkpoint (GO:0000076)3.43945027
41dosage compensation (GO:0007549)3.36964803
42regulation of centrosome duplication (GO:0010824)3.36019310
43regulation of histone H3-K9 methylation (GO:0051570)3.35701879
44telomere maintenance via telomere lengthening (GO:0010833)3.33834559
45regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.31300343
46regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.29531561
47nuclear envelope organization (GO:0006998)3.28898925
48telomere maintenance (GO:0000723)3.27202929
49nucleotide-excision repair, DNA gap filling (GO:0006297)3.26917924
50sister chromatid segregation (GO:0000819)3.26457884
51DNA replication-dependent nucleosome organization (GO:0034723)3.25292734
52DNA replication-dependent nucleosome assembly (GO:0006335)3.25292734
53DNA unwinding involved in DNA replication (GO:0006268)3.25256315
54DNA topological change (GO:0006265)3.23639361
55positive regulation of cell cycle checkpoint (GO:1901978)3.23187697
56telomere organization (GO:0032200)3.23119390
57histone exchange (GO:0043486)3.22982919
58mitotic sister chromatid segregation (GO:0000070)3.22658476
59chromosome condensation (GO:0030261)3.22021285
60positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.20748237
61regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.19575418
62nuclear envelope disassembly (GO:0051081)3.19072470
63membrane disassembly (GO:0030397)3.19072470
64negative regulation of cell cycle G2/M phase transition (GO:1902750)3.19066363
65negative regulation of DNA-dependent DNA replication (GO:2000104)3.16446397
66protein K6-linked ubiquitination (GO:0085020)3.15173200
67positive regulation of chromosome segregation (GO:0051984)3.13122624
68negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.09488125
69DNA packaging (GO:0006323)3.09249999
70regulation of spindle organization (GO:0090224)3.04598383
71regulation of nucleobase-containing compound transport (GO:0032239)3.02692703
72maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.02590663
73chromatin assembly or disassembly (GO:0006333)3.02048285
74mismatch repair (GO:0006298)3.01982264
75regulation of DNA damage checkpoint (GO:2000001)3.01800763
76histone phosphorylation (GO:0016572)3.00968452
77spliceosomal tri-snRNP complex assembly (GO:0000244)3.00382196
78ribosomal small subunit assembly (GO:0000028)2.99297121
79DNA geometric change (GO:0032392)2.99296229
80regulation of mitotic metaphase/anaphase transition (GO:0030071)2.99010693
81DNA ligation (GO:0006266)2.98965346
82nucleosome assembly (GO:0006334)2.98552596
83DNA duplex unwinding (GO:0032508)2.98504707
84regulation of nuclear cell cycle DNA replication (GO:0033262)2.95764565
85somatic cell DNA recombination (GO:0016444)2.95488360
86somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.95488360
87histone H3-K36 demethylation (GO:0070544)2.94304927
88translesion synthesis (GO:0019985)2.93742080
89DNA synthesis involved in DNA repair (GO:0000731)2.92635339
90regulation of histone methylation (GO:0031060)2.92491014
91regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.92451744
92chromosome segregation (GO:0007059)2.92404674
93IMP metabolic process (GO:0046040)2.92033150
94replication fork processing (GO:0031297)2.91712124
95spindle checkpoint (GO:0031577)2.91440134
96regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.90052305
97regulation of mitotic spindle checkpoint (GO:1903504)2.90052305
98peptidyl-lysine dimethylation (GO:0018027)2.87533652
99DNA biosynthetic process (GO:0071897)2.87194141
100regulation of sister chromatid segregation (GO:0033045)2.85000442
101regulation of mitotic sister chromatid separation (GO:0010965)2.85000442
102regulation of mitotic sister chromatid segregation (GO:0033047)2.85000442
103sister chromatid cohesion (GO:0007062)2.83736620
104nucleobase biosynthetic process (GO:0046112)2.82392343
105regulation of sister chromatid cohesion (GO:0007063)2.82227355
106regulation of double-strand break repair via homologous recombination (GO:0010569)2.79685237
107purine nucleobase biosynthetic process (GO:0009113)2.79014293
108regulation of mitotic spindle organization (GO:0060236)2.77097517
109histone mRNA catabolic process (GO:0071044)2.75252716
110spindle assembly checkpoint (GO:0071173)2.75235172
111DNA conformation change (GO:0071103)2.75060454
112regulation of chromosome segregation (GO:0051983)2.73657320
113somatic hypermutation of immunoglobulin genes (GO:0016446)2.72758663
114somatic diversification of immune receptors via somatic mutation (GO:0002566)2.72758663
115RNA-dependent DNA replication (GO:0006278)2.71809464
116ATP-dependent chromatin remodeling (GO:0043044)2.71447739
117negative regulation of chromosome segregation (GO:0051985)2.71317011
118negative regulation of mitotic sister chromatid separation (GO:2000816)2.71076014
119negative regulation of mitotic sister chromatid segregation (GO:0033048)2.71076014
120negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.71076014
121negative regulation of sister chromatid segregation (GO:0033046)2.71076014
122protein localization to chromosome (GO:0034502)2.68107231
123mitotic G2/M transition checkpoint (GO:0044818)2.67716105
124negative regulation of histone methylation (GO:0031061)2.66871422
125hepatocyte apoptotic process (GO:0097284)2.66793033
126regulation of centrosome cycle (GO:0046605)2.66333917
127negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.63409572
128DNA replication (GO:0006260)2.62573539
129mitotic spindle assembly checkpoint (GO:0007094)2.61614352
130mitotic spindle checkpoint (GO:0071174)2.60720063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.83970260
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.28313364
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.46182310
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.03851523
5* MYC_18555785_ChIP-Seq_MESCs_Mouse2.84369129
6E2F1_21310950_ChIP-Seq_MCF-7_Human2.44416795
7* EGR1_19374776_ChIP-ChIP_THP-1_Human2.41502121
8KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.28531941
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.22110016
10* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17188869
11NELFA_20434984_ChIP-Seq_ESCs_Mouse2.15205961
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.13464554
13* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.08724374
14STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.04345410
15E2F7_22180533_ChIP-Seq_HELA_Human10.7211958
16IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.98410927
17SALL1_21062744_ChIP-ChIP_HESCs_Human1.96349610
18EST1_17652178_ChIP-ChIP_JURKAT_Human1.96009768
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.88397200
20MYC_19079543_ChIP-ChIP_MESCs_Mouse1.88365726
21ELK1_19687146_ChIP-ChIP_HELA_Human1.86975760
22AR_21909140_ChIP-Seq_LNCAP_Human1.85512295
23VDR_23849224_ChIP-Seq_CD4+_Human1.84243057
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83683667
25TP63_19390658_ChIP-ChIP_HaCaT_Human1.83325443
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.80952091
27SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.80528900
28* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.78307496
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.77346582
30HOXB4_20404135_ChIP-ChIP_EML_Mouse1.76272860
31FOXP3_21729870_ChIP-Seq_TREG_Human1.72685102
32MYC_18358816_ChIP-ChIP_MESCs_Mouse1.70049468
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65545249
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.65254383
35CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.64341264
36FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.61059773
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58362513
38PKCTHETA_26484144_Chip-Seq_BREAST_Human1.57915831
39* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.57859327
40* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56557848
41MYC_22102868_ChIP-Seq_BL_Human1.56045552
42GABP_17652178_ChIP-ChIP_JURKAT_Human1.54576669
43MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52824815
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.50648536
45FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.50167069
46* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.48358216
47CIITA_25753668_ChIP-Seq_RAJI_Human1.46645991
48* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42839716
49ERG_20887958_ChIP-Seq_HPC-7_Mouse1.42247050
50BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.39151146
51IRF8_21731497_ChIP-ChIP_J774_Mouse1.38711662
52POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37802273
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37167376
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.35911686
55* XRN2_22483619_ChIP-Seq_HELA_Human1.34616650
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.34340930
57ETS1_20019798_ChIP-Seq_JURKAT_Human1.33563596
58DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.33451353
59* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.31689431
60DCP1A_22483619_ChIP-Seq_HELA_Human1.31311593
61* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.27920266
62* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27437885
63MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.27150325
64TTF2_22483619_ChIP-Seq_HELA_Human1.21759932
65SCL_19346495_ChIP-Seq_HPC-7_Human1.20047879
66* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18926959
67E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.18699055
68SPI1_23547873_ChIP-Seq_NB4_Human1.18430787
69FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18388808
70BP1_19119308_ChIP-ChIP_Hs578T_Human1.15720364
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.15159740
72SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.15103902
73STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.15070711
74STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.13984700
75TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13683236
76* CHD1_26751641_Chip-Seq_LNCaP_Human1.12732093
77* KDM5A_27292631_Chip-Seq_BREAST_Human1.12254524
78* TFEB_21752829_ChIP-Seq_HELA_Human1.11577168
79* MYB_26560356_Chip-Seq_TH1_Human1.11076161
80GABP_19822575_ChIP-Seq_HepG2_Human1.10648433
81* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.10345818
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.10243532
83HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09978169
84* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09923442
85MYB_21317192_ChIP-Seq_ERMYB_Mouse1.09387705
86* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.08192120
87SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.07836848
88* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.06464692
89ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.06172511
90CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.06113470
91* MAF_26560356_Chip-Seq_TH1_Human1.05132661
92ZFX_18555785_ChIP-Seq_MESCs_Mouse1.03814890
93NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.02886451
94RBPJ_22232070_ChIP-Seq_NCS_Mouse1.01455448
95* MYB_26560356_Chip-Seq_TH2_Human1.00628652
96GATA1_22025678_ChIP-Seq_K562_Human1.00057979
97* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98423774
98* SRF_21415370_ChIP-Seq_HL-1_Mouse0.95843124
99KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.95789540
100POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.94273016
101IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.93066181
102THAP11_20581084_ChIP-Seq_MESCs_Mouse0.93025047
103HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.90274095
104RUNX1_22412390_ChIP-Seq_EML_Mouse0.89946763
105TCF7_22412390_ChIP-Seq_EML_Mouse0.89893700
106SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.89041739
107BRD4_27068464_Chip-Seq_AML-cells_Mouse0.88073442
108PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.88057234
109* VDR_21846776_ChIP-Seq_THP-1_Human0.87387286
110DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.86926000
111HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.83784679
112STAT3_1855785_ChIP-Seq_MESCs_Mouse0.83747935
113ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.83403494
114NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.82469169
115CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.81865096
116ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81798433
117GATA2_22383799_ChIP-Seq_G1ME_Mouse0.81742476
118MYC_18940864_ChIP-ChIP_HL60_Human0.81119292
119* MAF_26560356_Chip-Seq_TH2_Human0.79439259
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.77394677
121* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77289352
122* UTX_26944678_Chip-Seq_JUKART_Human0.76576767
123EWS_26573619_Chip-Seq_HEK293_Human0.76085204
124ETS1_22383799_ChIP-Seq_G1ME_Mouse0.76015560
125POU5F1_16153702_ChIP-ChIP_HESCs_Human0.73810632

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.97295251
2MP0008057_abnormal_DNA_replication3.53138409
3MP0003693_abnormal_embryo_hatching3.43687972
4MP0003111_abnormal_nucleus_morphology3.27967596
5MP0003077_abnormal_cell_cycle3.19789245
6MP0008007_abnormal_cellular_replicative2.94192044
7MP0008058_abnormal_DNA_repair2.79671994
8MP0002396_abnormal_hematopoietic_system2.54134229
9MP0010307_abnormal_tumor_latency2.52350473
10MP0004957_abnormal_blastocyst_morpholog2.51763379
11MP0008877_abnormal_DNA_methylation2.39885548
12MP0002009_preneoplasia2.14889758
13MP0001835_abnormal_antigen_presentation2.05180117
14MP0003786_premature_aging1.97527267
15MP0010352_gastrointestinal_tract_polyps1.77678030
16MP0000569_abnormal_digit_pigmentation1.77278070
17MP0002166_altered_tumor_susceptibility1.76672459
18MP0003763_abnormal_thymus_physiology1.72042847
19MP0000490_abnormal_crypts_of1.71784744
20* MP0004808_abnormal_hematopoietic_stem1.70521233
21MP0000350_abnormal_cell_proliferation1.70453317
22MP0002006_tumorigenesis1.64997166
23MP0003787_abnormal_imprinting1.58645529
24MP0008932_abnormal_embryonic_tissue1.51341494
25MP0003121_genomic_imprinting1.49139034
26* MP0002398_abnormal_bone_marrow1.48848472
27MP0005397_hematopoietic_system_phenotyp1.41148089
28MP0001545_abnormal_hematopoietic_system1.41148089
29MP0004233_abnormal_muscle_weight1.40904119
30MP0005083_abnormal_biliary_tract1.39180990
31MP0001672_abnormal_embryogenesis/_devel1.38398755
32MP0005380_embryogenesis_phenotype1.38398755
33MP0001661_extended_life_span1.38165418
34MP0002877_abnormal_melanocyte_morpholog1.37109895
35MP0005075_abnormal_melanosome_morpholog1.34497179
36MP0005671_abnormal_response_to1.31764394
37MP0004185_abnormal_adipocyte_glucose1.30955536
38MP0001800_abnormal_humoral_immune1.30777921
39* MP0000689_abnormal_spleen_morphology1.30160518
40MP0009333_abnormal_splenocyte_physiolog1.28795485
41MP0003567_abnormal_fetal_cardiomyocyte1.28159072
42MP0002019_abnormal_tumor_incidence1.27998299
43MP0000015_abnormal_ear_pigmentation1.26517375
44MP0001730_embryonic_growth_arrest1.26388205
45MP0003984_embryonic_growth_retardation1.25909189
46MP0002722_abnormal_immune_system1.25641714
47MP0006054_spinal_hemorrhage1.25549581
48MP0009697_abnormal_copulation1.24237060
49MP0002088_abnormal_embryonic_growth/wei1.23632850
50MP0000703_abnormal_thymus_morphology1.23595099
51MP0002452_abnormal_antigen_presenting1.23462490
52MP0000313_abnormal_cell_death1.20167656
53MP0003123_paternal_imprinting1.19762395
54MP0005408_hypopigmentation1.19705085
55MP0005076_abnormal_cell_differentiation1.18374477
56MP0003943_abnormal_hepatobiliary_system1.16578334
57MP0005174_abnormal_tail_pigmentation1.16322448
58MP0002086_abnormal_extraembryonic_tissu1.15163747
59* MP0000716_abnormal_immune_system1.14175247
60MP0002420_abnormal_adaptive_immunity1.13999866
61MP0002132_abnormal_respiratory_system1.12788203
62MP0004197_abnormal_fetal_growth/weight/1.12717706
63MP0001819_abnormal_immune_cell1.12550459
64* MP0002429_abnormal_blood_cell1.10462887
65MP0001873_stomach_inflammation1.09928261
66MP0009785_altered_susceptibility_to1.07565145
67MP0002095_abnormal_skin_pigmentation1.07061654
68MP0001697_abnormal_embryo_size1.05955300
69MP0000371_diluted_coat_color1.04313669
70MP0002723_abnormal_immune_serum1.02967355
71MP0005621_abnormal_cell_physiology1.02782340
72MP0001293_anophthalmia1.02230936
73MP0001119_abnormal_female_reproductive1.02199260
74MP0003221_abnormal_cardiomyocyte_apopto1.00939427
75MP0000537_abnormal_urethra_morphology1.00020285
76MP0005000_abnormal_immune_tolerance0.98691589
77MP0001853_heart_inflammation0.97763420
78MP0003890_abnormal_embryonic-extraembry0.97525053
79MP0002405_respiratory_system_inflammati0.96971073
80MP0006292_abnormal_olfactory_placode0.96188017
81MP0009672_abnormal_birth_weight0.95982340
82MP0001915_intracranial_hemorrhage0.95260773
83MP0009703_decreased_birth_body0.94883692
84* MP0002080_prenatal_lethality0.92787388
85MP0010155_abnormal_intestine_physiology0.92300521
86MP0000566_synostosis0.92251074
87MP0005220_abnormal_exocrine_pancreas0.90986126
88MP0002148_abnormal_hypersensitivity_rea0.90939640
89MP0003436_decreased_susceptibility_to0.90874892
90MP0005384_cellular_phenotype0.89342806
91MP0002085_abnormal_embryonic_tissue0.89241050
92MP0002419_abnormal_innate_immunity0.88166554
93MP0006035_abnormal_mitochondrial_morpho0.87812449
94MP0003705_abnormal_hypodermis_morpholog0.87683696
95MP0000685_abnormal_immune_system0.87051763
96MP0001929_abnormal_gametogenesis0.86824720
97MP0002697_abnormal_eye_size0.86190111
98MP0002210_abnormal_sex_determination0.86043441
99MP0005451_abnormal_body_composition0.85039437
100MP0005025_abnormal_response_to0.84104581
101MP0001186_pigmentation_phenotype0.83339377
102MP0002092_abnormal_eye_morphology0.82383388
103MP0002075_abnormal_coat/hair_pigmentati0.82286551
104MP0000858_altered_metastatic_potential0.82117572
105MP0003448_altered_tumor_morphology0.81673693
106MP0000733_abnormal_muscle_development0.81056067
107MP0001790_abnormal_immune_system0.80973252
108MP0005387_immune_system_phenotype0.80973252
109MP0008995_early_reproductive_senescence0.80936346
110MP0003315_abnormal_perineum_morphology0.80258544
111MP0003828_pulmonary_edema0.80034391
112MP0005464_abnormal_platelet_physiology0.79746365
113MP0003718_maternal_effect0.78873797
114MP0003937_abnormal_limbs/digits/tail_de0.78421416
115MP0004782_abnormal_surfactant_physiolog0.77845047
116MP0002084_abnormal_developmental_patter0.76992562
117MP0003699_abnormal_female_reproductive0.76006080
118MP0005310_abnormal_salivary_gland0.75829923
119MP0000358_abnormal_cell_content/0.75475600
120MP0008961_abnormal_basal_metabolism0.73277419
121MP0004264_abnormal_extraembryonic_tissu0.72649696
122MP0003941_abnormal_skin_development0.72449188
123MP0010234_abnormal_vibrissa_follicle0.72078053
124MP0001346_abnormal_lacrimal_gland0.71661784
125MP0009278_abnormal_bone_marrow0.71488472
126MP0000428_abnormal_craniofacial_morphol0.71274868
127MP0003656_abnormal_erythrocyte_physiolo0.71036817
128MP0002160_abnormal_reproductive_system0.70628417
129MP0001145_abnormal_male_reproductive0.69912878
130MP0003566_abnormal_cell_adhesion0.69611967
131MP0003950_abnormal_plasma_membrane0.67577889
132MP0005647_abnormal_sex_gland0.65344324
133MP0002111_abnormal_tail_morphology0.63433287
134MP0005266_abnormal_metabolism0.62879710
135MP0001286_abnormal_eye_development0.62752409
136MP0010678_abnormal_skin_adnexa0.62248514
137MP0002970_abnormal_white_adipose0.61098696
138MP0003091_abnormal_cell_migration0.59960916
139MP0000653_abnormal_sex_gland0.59868693
140MP0002269_muscular_atrophy0.57387509

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.78508712
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.70901830
3Birth length less than 3rd percentile (HP:0003561)3.73213280
4Abnormality of chromosome stability (HP:0003220)3.73136489
5Ectopic kidney (HP:0000086)3.15209091
6Abnormality of the fingertips (HP:0001211)3.11852266
7Meckel diverticulum (HP:0002245)3.02655364
8Syringomyelia (HP:0003396)2.99326918
9Spinal cord lesions (HP:0100561)2.99326918
10Aplasia/Hypoplasia of the uvula (HP:0010293)2.92400167
11Microvesicular hepatic steatosis (HP:0001414)2.91916487
12Abnormality of the preputium (HP:0100587)2.91756960
13Myelodysplasia (HP:0002863)2.89235053
14Abnormality of the ileum (HP:0001549)2.88810767
1511 pairs of ribs (HP:0000878)2.77783776
16Medulloblastoma (HP:0002885)2.73237733
17Clubbing of toes (HP:0100760)2.72052093
18Progressive muscle weakness (HP:0003323)2.70097870
19Impulsivity (HP:0100710)2.67538497
20Sandal gap (HP:0001852)2.65298918
21Volvulus (HP:0002580)2.65135686
22Absent frontal sinuses (HP:0002688)2.64922899
23Progressive external ophthalmoplegia (HP:0000590)2.61298718
24Colitis (HP:0002583)2.56996165
25Acute myeloid leukemia (HP:0004808)2.49682550
26Duodenal stenosis (HP:0100867)2.48057911
27Small intestinal stenosis (HP:0012848)2.48057911
28Agnosia (HP:0010524)2.43184867
29Heterotopia (HP:0002282)2.42964701
30Lymphoma (HP:0002665)2.41945876
31Degeneration of anterior horn cells (HP:0002398)2.41444565
32Abnormality of the anterior horn cell (HP:0006802)2.41444565
33Reticulocytopenia (HP:0001896)2.40561004
34Selective tooth agenesis (HP:0001592)2.38502330
35Patellar aplasia (HP:0006443)2.37308016
36Duplicated collecting system (HP:0000081)2.36252699
37Sloping forehead (HP:0000340)2.34938485
38Absent thumb (HP:0009777)2.33229316
39Cutaneous melanoma (HP:0012056)2.30249629
40Abnormal lung lobation (HP:0002101)2.29096333
41Aplastic anemia (HP:0001915)2.28750256
42Bone marrow hypocellularity (HP:0005528)2.26453033
43Long eyelashes (HP:0000527)2.24769419
44IgM deficiency (HP:0002850)2.23858704
45Overlapping toe (HP:0001845)2.23431793
46Thrombocytosis (HP:0001894)2.22213681
47Aplasia involving forearm bones (HP:0009822)2.21190828
48Absent forearm bone (HP:0003953)2.21190828
49Aplasia/Hypoplasia of the patella (HP:0006498)2.20244649
50Abnormality of the renal collecting system (HP:0004742)2.19422960
51Dysmetric saccades (HP:0000641)2.19164624
52Nephroblastoma (Wilms tumor) (HP:0002667)2.19044031
53Rhabdomyosarcoma (HP:0002859)2.17938599
54Abnormality of T cell number (HP:0011839)2.17046212
55Arteriovenous malformation (HP:0100026)2.13871815
56Hypoplasia of the thymus (HP:0000778)2.12845683
57T lymphocytopenia (HP:0005403)2.12486482
58Combined immunodeficiency (HP:0005387)2.11353766
59Cleft eyelid (HP:0000625)2.11005952
60Abnormality of DNA repair (HP:0003254)2.10476259
61Increased nuchal translucency (HP:0010880)2.10416832
62Abnormality of the duodenum (HP:0002246)2.10209362
63Septate vagina (HP:0001153)2.08304479
64Sparse lateral eyebrow (HP:0005338)2.07650574
65Embryonal renal neoplasm (HP:0011794)2.06199404
66Panhypogammaglobulinemia (HP:0003139)2.05762995
67Prostate neoplasm (HP:0100787)2.04835281
68Abnormality of the astrocytes (HP:0100707)2.04271841
69Astrocytoma (HP:0009592)2.04271841
70Autoimmune thrombocytopenia (HP:0001973)2.03974109
71Abnormality of chromosome segregation (HP:0002916)2.03722393
72Abnormality of cochlea (HP:0000375)2.03132525
73Deep philtrum (HP:0002002)2.02036205
74Abnormality of the carotid arteries (HP:0005344)2.01737901
75Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.00528120
76Intestinal fistula (HP:0100819)2.00338896
77Neonatal hypoglycemia (HP:0001998)1.98796327
78IgA deficiency (HP:0002720)1.98635138
79Truncal obesity (HP:0001956)1.98450486
80Amaurosis fugax (HP:0100576)1.97665420
81Abnormal delayed hypersensitivity skin test (HP:0002963)1.97330600
82Submucous cleft hard palate (HP:0000176)1.96303026
83High anterior hairline (HP:0009890)1.94580671
84Deviation of the thumb (HP:0009603)1.94537415
85Breast hypoplasia (HP:0003187)1.94032800
86Short 4th metacarpal (HP:0010044)1.93805678
87Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.93805678
88Proximal placement of thumb (HP:0009623)1.93164740
89Oral leukoplakia (HP:0002745)1.91625043
90Obsessive-compulsive behavior (HP:0000722)1.91240692
91Basal cell carcinoma (HP:0002671)1.90475736
92Glioma (HP:0009733)1.89323183
93Recurrent viral infections (HP:0004429)1.89013075
94Poikiloderma (HP:0001029)1.88849110
95Abnormality of T cells (HP:0002843)1.87905178
96Optic nerve coloboma (HP:0000588)1.87690429
97Abnormality of B cell number (HP:0010975)1.87565754
98B lymphocytopenia (HP:0010976)1.87565754
99Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.87532778
100IgG deficiency (HP:0004315)1.86737550
101Viral hepatitis (HP:0006562)1.86716513
102Colon cancer (HP:0003003)1.86217264
103Premature graying of hair (HP:0002216)1.85403750
104Premature ovarian failure (HP:0008209)1.85106250
105Leukopenia (HP:0001882)1.85076592
106Ureteral duplication (HP:0000073)1.84907321
107Abnormal spermatogenesis (HP:0008669)1.84382861
108Abnormality of T cell physiology (HP:0011840)1.84110339
109Intestinal atresia (HP:0011100)1.84084470
110Periodontitis (HP:0000704)1.82287767
111Cafe-au-lait spot (HP:0000957)1.81790264
112Homocystinuria (HP:0002156)1.81167478
113Abnormality of homocysteine metabolism (HP:0010919)1.81167478
114Long clavicles (HP:0000890)1.81124933
115Severe combined immunodeficiency (HP:0004430)1.81092572
116Low anterior hairline (HP:0000294)1.80249068
117Ependymoma (HP:0002888)1.79187518
118Mediastinal lymphadenopathy (HP:0100721)1.78818587
119Hypergonadotropic hypogonadism (HP:0000815)1.78528341
120Recurrent abscess formation (HP:0002722)1.76720001
121Abnormality of pyrimidine metabolism (HP:0004353)1.76469795
122Abnormality of the columella (HP:0009929)1.76249944
123Cellular immunodeficiency (HP:0005374)1.76106904
124Acute lymphatic leukemia (HP:0006721)1.75462807
125Neoplasm of the adrenal cortex (HP:0100641)1.74178690
126Prominent nose (HP:0000448)1.73275506
127Facial hemangioma (HP:0000329)1.72950451
128Urethral obstruction (HP:0000796)1.72762056
129Short thumb (HP:0009778)1.72169077
130Dislocated radial head (HP:0003083)1.72164847
131Pulmonary fibrosis (HP:0002206)1.72094380
132Thyroiditis (HP:0100646)1.71858891
133Abnormality of the prostate (HP:0008775)1.71823175
134Choanal atresia (HP:0000453)1.70119006
135Abnormality of cells of the lymphoid lineage (HP:0012140)1.69197112
136Abnormality of the nasal septum (HP:0000419)1.68273162
137Subacute progressive viral hepatitis (HP:0006572)1.68133970
138Renal cortical cysts (HP:0000803)1.67367253
139Absent radius (HP:0003974)1.65704064
140Abnormality of the frontal sinuses (HP:0002687)1.65333631
141Agammaglobulinemia (HP:0004432)1.63057204
142Lymphopenia (HP:0001888)1.62516768
143Recurrent fungal infections (HP:0002841)1.62507202
144Anal stenosis (HP:0002025)1.62244296
145Squamous cell carcinoma (HP:0002860)1.61242029
146Lip pit (HP:0100267)1.59964083
147Supernumerary spleens (HP:0009799)1.58941526
148Tracheoesophageal fistula (HP:0002575)1.58595318
149Prominent metopic ridge (HP:0005487)1.57560663
150Granulocytopenia (HP:0001913)1.57400246

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.54933007
2ZAK3.23332114
3MKNK23.05837081
4MKNK12.97467417
5SRPK12.81337238
6CDK122.55376666
7WEE12.41472061
8TLK12.32391735
9BRD42.32355884
10ACVR1B2.14196012
11ICK2.11542206
12MAP3K142.06186605
13PLK42.02771854
14BRSK21.98688090
15PDK21.98072689
16CAMK1D1.93988198
17EIF2AK11.92393194
18STK41.91566077
19BUB11.85048604
20CAMK1G1.83079306
21ATR1.77960577
22PIM11.75622890
23NEK21.74927835
24VRK11.57676190
25TTK1.55218513
26AURKB1.47434554
27PLK11.47140458
28CDK41.43536566
29SCYL21.42214875
30CHEK21.41317731
31SMG11.39508637
32EIF2AK21.34043009
33STK31.27704079
34PRPF4B1.26138529
35RAF11.25514380
36JAK31.25092284
37STK101.24564291
38MAP4K11.24503504
39MTOR1.23202635
40CDK71.22500383
41YES11.22485605
42RPS6KA41.22444697
43NUAK11.21189167
44TEC1.20816983
45TRIB31.19593142
46STK38L1.19416135
47PLK31.17324358
48CLK11.17323221
49CDK61.17002645
50TXK1.16241123
51MAPK111.15815405
52PASK1.15595180
53FRK1.14528056
54NEK91.13863996
55CHUK1.13779421
56CDK91.11530151
57IKBKB1.05485189
58IRAK41.03413636
59NEK11.02747306
60IRAK31.02735960
61ATM0.98966879
62EIF2AK30.98836055
63CDK80.98077660
64CHEK10.96671610
65SGK20.95750015
66IKBKE0.91348308
67STK240.90940018
68FLT30.90284810
69RPS6KB20.89067124
70LATS10.86266756
71RPS6KA50.84705490
72TSSK60.84647256
73MELK0.82872274
74ERBB30.82097570
75AKT30.80768505
76EPHA20.79260798
77TRPM70.77460741
78MAP3K60.77176045
79MAP3K80.75351534
80TGFBR10.74800883
81BTK0.72965057
82FGFR30.69695263
83CDK20.69620480
84BRSK10.68326550
85DYRK30.67833294
86TYK20.66878302
87MAP2K30.66224290
88STK390.65513099
89NME20.62636268
90PBK0.57387681
91CCNB10.56479764
92SGK30.55447979
93SIK30.54473863
94MAP3K130.53753039
95BLK0.53717875
96CDK10.53260308
97PRKAA10.52658287
98BRAF0.52180019
99NLK0.51589523
100MARK30.51115516
101PKN20.50717781
102BMPR1B0.50679097
103RPS6KB10.50332655
104KIT0.48048549
105AURKA0.47324162
106CSNK2A10.46841307
107CSF1R0.46272436
108BMPR20.46048312
109GSK3B0.45813121
110MAPK140.45506014
111RPS6KA60.45285669
112PIM20.44743923
113TIE10.43842810
114MAP3K100.42433031
115ZAP700.41916111
116NEK60.41631118
117EEF2K0.41507826
118PRKDC0.40628120
119MST40.40249552
120AKT10.39891494
121CDK30.38960851
122MST1R0.38432752
123RPS6KC10.37662075
124RPS6KA10.35956580
125MAPK100.35084693
126CAMK40.33343277
127MAPK10.32586366
128MAP3K70.28201697
129WNK10.28064796
130SIK20.27952542

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.51531606
2Mismatch repair_Homo sapiens_hsa034303.84251341
3Homologous recombination_Homo sapiens_hsa034403.15130137
4Base excision repair_Homo sapiens_hsa034102.96606472
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.85940074
6Cell cycle_Homo sapiens_hsa041102.74392533
7Fanconi anemia pathway_Homo sapiens_hsa034602.63046061
8Systemic lupus erythematosus_Homo sapiens_hsa053222.60781057
9Nucleotide excision repair_Homo sapiens_hsa034202.49844860
10One carbon pool by folate_Homo sapiens_hsa006702.39174440
11Spliceosome_Homo sapiens_hsa030402.33140723
12Non-homologous end-joining_Homo sapiens_hsa034502.26043725
13RNA transport_Homo sapiens_hsa030132.20002992
14Basal transcription factors_Homo sapiens_hsa030221.94468325
15RNA polymerase_Homo sapiens_hsa030201.94250623
16RNA degradation_Homo sapiens_hsa030181.86012101
17Pyrimidine metabolism_Homo sapiens_hsa002401.70065454
18p53 signaling pathway_Homo sapiens_hsa041151.69830697
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.69428239
20Herpes simplex infection_Homo sapiens_hsa051681.63617030
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.59184588
22mRNA surveillance pathway_Homo sapiens_hsa030151.57918189
23NF-kappa B signaling pathway_Homo sapiens_hsa040641.54556868
24Viral carcinogenesis_Homo sapiens_hsa052031.42703409
25Transcriptional misregulation in cancer_Homo sapiens_hsa052021.34272841
26Measles_Homo sapiens_hsa051621.32483459
27Primary immunodeficiency_Homo sapiens_hsa053401.23161359
28Legionellosis_Homo sapiens_hsa051341.19370091
29Epstein-Barr virus infection_Homo sapiens_hsa051691.19038072
30Antigen processing and presentation_Homo sapiens_hsa046121.17818486
31Intestinal immune network for IgA production_Homo sapiens_hsa046721.14344027
32Ribosome_Homo sapiens_hsa030101.11539761
33MicroRNAs in cancer_Homo sapiens_hsa052061.10050993
34Selenocompound metabolism_Homo sapiens_hsa004501.05863422
35RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.04823948
36Small cell lung cancer_Homo sapiens_hsa052221.04734487
37HTLV-I infection_Homo sapiens_hsa051661.00622856
38Allograft rejection_Homo sapiens_hsa053301.00611046
39Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.99310129
40Influenza A_Homo sapiens_hsa051640.98466320
41mTOR signaling pathway_Homo sapiens_hsa041500.96965643
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96188820
43Hepatitis B_Homo sapiens_hsa051610.95420063
44Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.95129422
45Hematopoietic cell lineage_Homo sapiens_hsa046400.93617124
46NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93198095
47Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.92454307
48Purine metabolism_Homo sapiens_hsa002300.91795512
49Proteasome_Homo sapiens_hsa030500.91764114
50Graft-versus-host disease_Homo sapiens_hsa053320.91255433
51Alcoholism_Homo sapiens_hsa050340.88592635
52Apoptosis_Homo sapiens_hsa042100.86119624
53Leishmaniasis_Homo sapiens_hsa051400.84844759
54Bladder cancer_Homo sapiens_hsa052190.78393403
55Jak-STAT signaling pathway_Homo sapiens_hsa046300.77860977
56Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73399302
57Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72095133
58Notch signaling pathway_Homo sapiens_hsa043300.72017083
59Inositol phosphate metabolism_Homo sapiens_hsa005620.71479023
60Glioma_Homo sapiens_hsa052140.68397106
61Toll-like receptor signaling pathway_Homo sapiens_hsa046200.66383973
62Chronic myeloid leukemia_Homo sapiens_hsa052200.64601358
63Viral myocarditis_Homo sapiens_hsa054160.63788593
64Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62820017
65B cell receptor signaling pathway_Homo sapiens_hsa046620.62706672
66Prostate cancer_Homo sapiens_hsa052150.61396552
67Autoimmune thyroid disease_Homo sapiens_hsa053200.60392178
68Central carbon metabolism in cancer_Homo sapiens_hsa052300.60276562
69Thyroid cancer_Homo sapiens_hsa052160.59296002
70ErbB signaling pathway_Homo sapiens_hsa040120.59264644
71Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58663958
72Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.58449782
73Lysine degradation_Homo sapiens_hsa003100.58209784
74Toxoplasmosis_Homo sapiens_hsa051450.58103636
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54756873
76Acute myeloid leukemia_Homo sapiens_hsa052210.53304738
77Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53265803
78TNF signaling pathway_Homo sapiens_hsa046680.53175987
79Asthma_Homo sapiens_hsa053100.53067108
80Renal cell carcinoma_Homo sapiens_hsa052110.52554637
81TGF-beta signaling pathway_Homo sapiens_hsa043500.52074426
82Adherens junction_Homo sapiens_hsa045200.45862338
83Pancreatic cancer_Homo sapiens_hsa052120.45754984
84Biosynthesis of amino acids_Homo sapiens_hsa012300.45508197
85FoxO signaling pathway_Homo sapiens_hsa040680.45505349
86Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.45026062
87Malaria_Homo sapiens_hsa051440.44951580
88Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44628335
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.44306615
90Oocyte meiosis_Homo sapiens_hsa041140.43563014
91Type II diabetes mellitus_Homo sapiens_hsa049300.43035750
92Melanoma_Homo sapiens_hsa052180.42838702
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.42699861
94Shigellosis_Homo sapiens_hsa051310.41640897
95AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.41100109
96Osteoclast differentiation_Homo sapiens_hsa043800.41048402
97Drug metabolism - other enzymes_Homo sapiens_hsa009830.40684386
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.40216469
99HIF-1 signaling pathway_Homo sapiens_hsa040660.38966694
100Colorectal cancer_Homo sapiens_hsa052100.38422157
101Fatty acid biosynthesis_Homo sapiens_hsa000610.37356420
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.37021488
103Caffeine metabolism_Homo sapiens_hsa002320.36783022
104Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36462749
105Tuberculosis_Homo sapiens_hsa051520.34990844
106Cysteine and methionine metabolism_Homo sapiens_hsa002700.34956891
107T cell receptor signaling pathway_Homo sapiens_hsa046600.34203516
108Insulin signaling pathway_Homo sapiens_hsa049100.34186858
109Pentose phosphate pathway_Homo sapiens_hsa000300.33865922
110Choline metabolism in cancer_Homo sapiens_hsa052310.33831226
111Pathways in cancer_Homo sapiens_hsa052000.33632923
112Non-small cell lung cancer_Homo sapiens_hsa052230.33617476
113Proteoglycans in cancer_Homo sapiens_hsa052050.32758043
114Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32149665
115Type I diabetes mellitus_Homo sapiens_hsa049400.30775713
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.29105925
117Insulin resistance_Homo sapiens_hsa049310.28546932
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.28229062
119Hepatitis C_Homo sapiens_hsa051600.27612317
120Hippo signaling pathway_Homo sapiens_hsa043900.26798925
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25893237
122Pertussis_Homo sapiens_hsa051330.25485150
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25186467
124Wnt signaling pathway_Homo sapiens_hsa043100.25186224
125Prolactin signaling pathway_Homo sapiens_hsa049170.25168946
126AMPK signaling pathway_Homo sapiens_hsa041520.24729317
127Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.23548206
128Endometrial cancer_Homo sapiens_hsa052130.23482266
129Salmonella infection_Homo sapiens_hsa051320.22976497
130Adipocytokine signaling pathway_Homo sapiens_hsa049200.22847685
131Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.22695899

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