

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 6.96721405 |
| 2 | cellular response to electrical stimulus (GO:0071257) | 5.95101963 |
| 3 | cerebellar Purkinje cell differentiation (GO:0021702) | 5.59792177 |
| 4 | response to misfolded protein (GO:0051788) | 5.48021359 |
| 5 | endoderm formation (GO:0001706) | 5.06161668 |
| 6 | cell wall macromolecule catabolic process (GO:0016998) | 4.81617306 |
| 7 | cell wall macromolecule metabolic process (GO:0044036) | 4.80582562 |
| 8 | cytochrome complex assembly (GO:0017004) | 4.70201027 |
| 9 | positive regulation of gastrulation (GO:2000543) | 4.47532142 |
| 10 | somite rostral/caudal axis specification (GO:0032525) | 4.44058859 |
| 11 | glomerulus development (GO:0032835) | 4.43052651 |
| 12 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 4.33089774 |
| 13 | protein-cofactor linkage (GO:0018065) | 4.28133074 |
| 14 | detection of light stimulus involved in visual perception (GO:0050908) | 4.08749132 |
| 15 | detection of light stimulus involved in sensory perception (GO:0050962) | 4.08749132 |
| 16 | protein complex biogenesis (GO:0070271) | 4.06974690 |
| 17 | head development (GO:0060322) | 4.00489116 |
| 18 | regulation of centriole replication (GO:0046599) | 3.93604768 |
| 19 | positive regulation of amino acid transport (GO:0051957) | 3.81490919 |
| 20 | vagina development (GO:0060068) | 3.79870319 |
| 21 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.77176084 |
| 22 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.77176084 |
| 23 | nephron tubule morphogenesis (GO:0072078) | 3.76651513 |
| 24 | nephron epithelium morphogenesis (GO:0072088) | 3.76651513 |
| 25 | renal tubule morphogenesis (GO:0061333) | 3.69949629 |
| 26 | DNA double-strand break processing (GO:0000729) | 3.63229297 |
| 27 | regulation of sensory perception (GO:0051931) | 3.61864203 |
| 28 | regulation of sensory perception of pain (GO:0051930) | 3.61864203 |
| 29 | behavioral response to nicotine (GO:0035095) | 3.61094085 |
| 30 | kidney morphogenesis (GO:0060993) | 3.59927084 |
| 31 | sequestering of actin monomers (GO:0042989) | 3.58246294 |
| 32 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.56191164 |
| 33 | coenzyme catabolic process (GO:0009109) | 3.53958084 |
| 34 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.43122798 |
| 35 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.43122798 |
| 36 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.43122798 |
| 37 | protein neddylation (GO:0045116) | 3.42689840 |
| 38 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.35743963 |
| 39 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.33776489 |
| 40 | urogenital system development (GO:0001655) | 3.31767431 |
| 41 | DNA damage response, detection of DNA damage (GO:0042769) | 3.30548429 |
| 42 | glutamate receptor signaling pathway (GO:0007215) | 3.29625563 |
| 43 | female genitalia development (GO:0030540) | 3.28446099 |
| 44 | respiratory chain complex IV assembly (GO:0008535) | 3.25546370 |
| 45 | spinal cord association neuron differentiation (GO:0021527) | 3.22529631 |
| 46 | arginine catabolic process (GO:0006527) | 3.22267580 |
| 47 | cornea development in camera-type eye (GO:0061303) | 3.17843863 |
| 48 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 3.17372438 |
| 49 | S-adenosylmethionine metabolic process (GO:0046500) | 3.16084221 |
| 50 | neuronal action potential (GO:0019228) | 3.15837331 |
| 51 | glycerophospholipid catabolic process (GO:0046475) | 3.13675898 |
| 52 | positive regulation of vesicle fusion (GO:0031340) | 3.05805634 |
| 53 | negative regulation of multicellular organism growth (GO:0040015) | 3.00822607 |
| 54 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 3.00738565 |
| 55 | primitive streak formation (GO:0090009) | 3.00130554 |
| 56 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.95494164 |
| 57 | dopamine transport (GO:0015872) | 2.89548353 |
| 58 | cell differentiation in spinal cord (GO:0021515) | 2.86808753 |
| 59 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.84816559 |
| 60 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.81259859 |
| 61 | regulation of respiratory system process (GO:0044065) | 2.78708726 |
| 62 | arginine metabolic process (GO:0006525) | 2.78560987 |
| 63 | negative regulation of protein localization to cell surface (GO:2000009) | 2.76953230 |
| 64 | positive regulation of embryonic development (GO:0040019) | 2.69874515 |
| 65 | protein import into peroxisome matrix (GO:0016558) | 2.69272662 |
| 66 | cellular ketone body metabolic process (GO:0046950) | 2.68698697 |
| 67 | serotonin receptor signaling pathway (GO:0007210) | 2.68678742 |
| 68 | anterograde synaptic vesicle transport (GO:0048490) | 2.64966599 |
| 69 | protein polyglutamylation (GO:0018095) | 2.63978591 |
| 70 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.63285966 |
| 71 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.62984933 |
| 72 | uterus development (GO:0060065) | 2.60175900 |
| 73 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 2.57991501 |
| 74 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.57051075 |
| 75 | neuron fate specification (GO:0048665) | 2.55175291 |
| 76 | L-methionine biosynthetic process (GO:0071265) | 2.54044152 |
| 77 | amino acid salvage (GO:0043102) | 2.54044152 |
| 78 | L-methionine salvage (GO:0071267) | 2.54044152 |
| 79 | endocrine pancreas development (GO:0031018) | 2.51923834 |
| 80 | cerebellum development (GO:0021549) | 2.51903325 |
| 81 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.51602371 |
| 82 | NADH dehydrogenase complex assembly (GO:0010257) | 2.51602371 |
| 83 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.51602371 |
| 84 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.49921060 |
| 85 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.49839821 |
| 86 | cell differentiation in hindbrain (GO:0021533) | 2.47840068 |
| 87 | detection of calcium ion (GO:0005513) | 2.47798990 |
| 88 | cardiac right ventricle morphogenesis (GO:0003215) | 2.46392219 |
| 89 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 2.45741935 |
| 90 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.45019343 |
| 91 | negative regulation of cell cycle arrest (GO:0071157) | 2.44644950 |
| 92 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.44643491 |
| 93 | anterograde axon cargo transport (GO:0008089) | 2.43119674 |
| 94 | reflex (GO:0060004) | 2.43061463 |
| 95 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.42788421 |
| 96 | ATP synthesis coupled proton transport (GO:0015986) | 2.42788421 |
| 97 | aldehyde catabolic process (GO:0046185) | 2.40073601 |
| 98 | ketone body metabolic process (GO:1902224) | 2.39301158 |
| 99 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.36636080 |
| 100 | pancreas development (GO:0031016) | 2.35831223 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.92330905 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.53010075 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.37916832 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.28275223 |
| 5 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.87010448 |
| 6 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.79621971 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.65791565 |
| 8 | FUS_26573619_Chip-Seq_HEK293_Human | 2.50268877 |
| 9 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.39679011 |
| 10 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.23463180 |
| 11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.22076564 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.21242963 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.19166447 |
| 14 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.12430307 |
| 15 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.10197760 |
| 16 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.02233950 |
| 17 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.00355857 |
| 18 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.99616176 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.99212209 |
| 20 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.93951450 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90977411 |
| 22 | P300_19829295_ChIP-Seq_ESCs_Human | 1.81142163 |
| 23 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.80944613 |
| 24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.80538691 |
| 25 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.77229467 |
| 26 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.71633126 |
| 27 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.66986052 |
| 28 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.63593154 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.60735555 |
| 30 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.56802234 |
| 31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.55166943 |
| 32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.54518793 |
| 33 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.52535087 |
| 34 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.51540367 |
| 35 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.49015720 |
| 36 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.46766741 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.46583171 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.46583171 |
| 39 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.45477374 |
| 40 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.44738458 |
| 41 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.43496433 |
| 42 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.41165981 |
| 43 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.41165717 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40113482 |
| 45 | STAT3_23295773_ChIP-Seq_U87_Human | 1.39472150 |
| 46 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.37361409 |
| 47 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.37361409 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.36681682 |
| 49 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.36264696 |
| 50 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.35702496 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.33329453 |
| 52 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.32480764 |
| 53 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.30563147 |
| 54 | TCF4_23295773_ChIP-Seq_U87_Human | 1.30544347 |
| 55 | NCOR_22424771_ChIP-Seq_293T_Human | 1.30270051 |
| 56 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.28175729 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27448931 |
| 58 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.24433674 |
| 59 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.21501355 |
| 60 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.20572479 |
| 61 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.20167000 |
| 62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.19111527 |
| 63 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.16212867 |
| 64 | AR_25329375_ChIP-Seq_VCAP_Human | 1.16109111 |
| 65 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.14303682 |
| 66 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.14303682 |
| 67 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.11875893 |
| 68 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.11271952 |
| 69 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.07623004 |
| 70 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06770880 |
| 71 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.05360335 |
| 72 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.04255007 |
| 73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.04088633 |
| 74 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.03933849 |
| 75 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.03642142 |
| 76 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03506605 |
| 77 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02348078 |
| 78 | ERA_21632823_ChIP-Seq_H3396_Human | 1.01611803 |
| 79 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.01513114 |
| 80 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.99809898 |
| 81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.98496125 |
| 82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.97342214 |
| 83 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.97069347 |
| 84 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96680425 |
| 85 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96513845 |
| 86 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.96411682 |
| 87 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.96338200 |
| 88 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.95945474 |
| 89 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.95854758 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94283825 |
| 91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94283825 |
| 92 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.93147393 |
| 93 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.92537577 |
| 94 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91778338 |
| 95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.91686131 |
| 96 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.90810397 |
| 97 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.90473173 |
| 98 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90082768 |
| 99 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.89894423 |
| 100 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.89875479 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003283_abnormal_digestive_organ | 5.12561506 |
| 2 | MP0003787_abnormal_imprinting | 3.56473866 |
| 3 | MP0001968_abnormal_touch/_nociception | 3.24873180 |
| 4 | MP0003890_abnormal_embryonic-extraembry | 2.85305050 |
| 5 | MP0002736_abnormal_nociception_after | 2.59064311 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.58880139 |
| 7 | MP0009046_muscle_twitch | 2.56109706 |
| 8 | MP0004043_abnormal_pH_regulation | 2.53279701 |
| 9 | MP0004147_increased_porphyrin_level | 2.39998536 |
| 10 | MP0003252_abnormal_bile_duct | 2.30615078 |
| 11 | MP0003195_calcinosis | 2.27554967 |
| 12 | MP0008877_abnormal_DNA_methylation | 2.25316449 |
| 13 | MP0002837_dystrophic_cardiac_calcinosis | 2.16368258 |
| 14 | MP0003646_muscle_fatigue | 2.08497184 |
| 15 | MP0003880_abnormal_central_pattern | 2.08392851 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 2.04683911 |
| 17 | MP0002557_abnormal_social/conspecific_i | 2.03322259 |
| 18 | MP0004924_abnormal_behavior | 2.00042909 |
| 19 | MP0005386_behavior/neurological_phenoty | 2.00042909 |
| 20 | MP0005253_abnormal_eye_physiology | 1.99969303 |
| 21 | MP0004885_abnormal_endolymph | 1.98374209 |
| 22 | MP0002272_abnormal_nervous_system | 1.91865454 |
| 23 | MP0003172_abnormal_lysosome_physiology | 1.78565090 |
| 24 | MP0004142_abnormal_muscle_tone | 1.75863600 |
| 25 | MP0002751_abnormal_autonomic_nervous | 1.74644208 |
| 26 | MP0003121_genomic_imprinting | 1.71552221 |
| 27 | MP0008995_early_reproductive_senescence | 1.69929513 |
| 28 | MP0000566_synostosis | 1.68348995 |
| 29 | MP0003136_yellow_coat_color | 1.65232633 |
| 30 | MP0002734_abnormal_mechanical_nocicepti | 1.63773258 |
| 31 | MP0000538_abnormal_urinary_bladder | 1.59744240 |
| 32 | MP0006292_abnormal_olfactory_placode | 1.53514724 |
| 33 | MP0001529_abnormal_vocalization | 1.50750455 |
| 34 | MP0006276_abnormal_autonomic_nervous | 1.49675011 |
| 35 | MP0002102_abnormal_ear_morphology | 1.47582743 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.46745961 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.42109902 |
| 38 | MP0002735_abnormal_chemical_nociception | 1.42060350 |
| 39 | MP0000427_abnormal_hair_cycle | 1.39871391 |
| 40 | MP0003786_premature_aging | 1.37340313 |
| 41 | MP0002938_white_spotting | 1.36031353 |
| 42 | MP0001986_abnormal_taste_sensitivity | 1.35561147 |
| 43 | MP0009745_abnormal_behavioral_response | 1.35052292 |
| 44 | MP0008872_abnormal_physiological_respon | 1.34122582 |
| 45 | MP0004133_heterotaxia | 1.32324861 |
| 46 | MP0002572_abnormal_emotion/affect_behav | 1.32243835 |
| 47 | MP0002067_abnormal_sensory_capabilities | 1.32142169 |
| 48 | MP0002693_abnormal_pancreas_physiology | 1.30978994 |
| 49 | MP0001756_abnormal_urination | 1.29597800 |
| 50 | MP0005174_abnormal_tail_pigmentation | 1.26359626 |
| 51 | MP0003122_maternal_imprinting | 1.23402827 |
| 52 | MP0002909_abnormal_adrenal_gland | 1.21811883 |
| 53 | MP0005379_endocrine/exocrine_gland_phen | 1.21670997 |
| 54 | MP0000569_abnormal_digit_pigmentation | 1.20277315 |
| 55 | MP0008875_abnormal_xenobiotic_pharmacok | 1.17994584 |
| 56 | MP0010386_abnormal_urinary_bladder | 1.15882037 |
| 57 | MP0000647_abnormal_sebaceous_gland | 1.13331456 |
| 58 | MP0002063_abnormal_learning/memory/cond | 1.12855178 |
| 59 | MP0002733_abnormal_thermal_nociception | 1.12282651 |
| 60 | MP0001970_abnormal_pain_threshold | 1.10384356 |
| 61 | MP0003635_abnormal_synaptic_transmissio | 1.09985080 |
| 62 | MP0001944_abnormal_pancreas_morphology | 1.09588798 |
| 63 | MP0003186_abnormal_redox_activity | 1.09254626 |
| 64 | MP0003137_abnormal_impulse_conducting | 1.09168742 |
| 65 | MP0001299_abnormal_eye_distance/ | 1.07939021 |
| 66 | MP0003011_delayed_dark_adaptation | 1.06902280 |
| 67 | MP0004019_abnormal_vitamin_homeostasis | 1.03190251 |
| 68 | MP0005083_abnormal_biliary_tract | 1.01021726 |
| 69 | MP0000955_abnormal_spinal_cord | 1.00450132 |
| 70 | MP0005423_abnormal_somatic_nervous | 0.99999128 |
| 71 | MP0002184_abnormal_innervation | 0.99252752 |
| 72 | MP0005646_abnormal_pituitary_gland | 0.98607214 |
| 73 | MP0005410_abnormal_fertilization | 0.98203142 |
| 74 | MP0005084_abnormal_gallbladder_morpholo | 0.97135679 |
| 75 | MP0001905_abnormal_dopamine_level | 0.93035710 |
| 76 | MP0000013_abnormal_adipose_tissue | 0.92448882 |
| 77 | MP0002139_abnormal_hepatobiliary_system | 0.91641736 |
| 78 | MP0001486_abnormal_startle_reflex | 0.90419149 |
| 79 | MP0003119_abnormal_digestive_system | 0.87217254 |
| 80 | MP0004742_abnormal_vestibular_system | 0.86222142 |
| 81 | MP0008775_abnormal_heart_ventricle | 0.86007112 |
| 82 | MP0002138_abnormal_hepatobiliary_system | 0.85346216 |
| 83 | MP0003878_abnormal_ear_physiology | 0.84641141 |
| 84 | MP0005377_hearing/vestibular/ear_phenot | 0.84641141 |
| 85 | MP0003718_maternal_effect | 0.83836080 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.80988474 |
| 87 | MP0005391_vision/eye_phenotype | 0.80845414 |
| 88 | MP0008058_abnormal_DNA_repair | 0.80221015 |
| 89 | MP0003698_abnormal_male_reproductive | 0.80209690 |
| 90 | MP0005220_abnormal_exocrine_pancreas | 0.79678355 |
| 91 | MP0002064_seizures | 0.78191249 |
| 92 | MP0002095_abnormal_skin_pigmentation | 0.76257315 |
| 93 | MP0000778_abnormal_nervous_system | 0.75866232 |
| 94 | MP0002638_abnormal_pupillary_reflex | 0.75596454 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 0.75256692 |
| 96 | MP0001348_abnormal_lacrimal_gland | 0.75212440 |
| 97 | MP0005187_abnormal_penis_morphology | 0.74330209 |
| 98 | MP0002882_abnormal_neuron_morphology | 0.74217053 |
| 99 | MP0002653_abnormal_ependyma_morphology | 0.74147316 |
| 100 | MP0002229_neurodegeneration | 0.73797812 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dysdiadochokinesis (HP:0002075) | 5.02472041 |
| 2 | Abnormal pancreas size (HP:0012094) | 4.86495124 |
| 3 | Genetic anticipation (HP:0003743) | 4.31371849 |
| 4 | Microretrognathia (HP:0000308) | 4.11277004 |
| 5 | Pancreatic fibrosis (HP:0100732) | 3.85290152 |
| 6 | Shawl scrotum (HP:0000049) | 3.77101853 |
| 7 | Decreased central vision (HP:0007663) | 3.51227368 |
| 8 | Horizontal nystagmus (HP:0000666) | 3.34839718 |
| 9 | Birth length less than 3rd percentile (HP:0003561) | 3.19386644 |
| 10 | Gaze-evoked nystagmus (HP:0000640) | 3.16983967 |
| 11 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.10166100 |
| 12 | Pancreatic cysts (HP:0001737) | 3.09094248 |
| 13 | Hyperventilation (HP:0002883) | 3.07775460 |
| 14 | Abnormal albumin level (HP:0012116) | 3.00747951 |
| 15 | Hypoalbuminemia (HP:0003073) | 3.00747951 |
| 16 | Pendular nystagmus (HP:0012043) | 3.00577644 |
| 17 | Abnormality of the renal cortex (HP:0011035) | 3.00122094 |
| 18 | Progressive cerebellar ataxia (HP:0002073) | 2.89664958 |
| 19 | True hermaphroditism (HP:0010459) | 2.88124559 |
| 20 | Esotropia (HP:0000565) | 2.87099009 |
| 21 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.78947282 |
| 22 | Renal cortical cysts (HP:0000803) | 2.74806012 |
| 23 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.74574814 |
| 24 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.74574814 |
| 25 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.63404221 |
| 26 | Congenital stationary night blindness (HP:0007642) | 2.62757168 |
| 27 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.58116505 |
| 28 | Acute necrotizing encephalopathy (HP:0006965) | 2.56450883 |
| 29 | 3-Methylglutaconic aciduria (HP:0003535) | 2.54832955 |
| 30 | Lissencephaly (HP:0001339) | 2.54684666 |
| 31 | Methylmalonic acidemia (HP:0002912) | 2.51720822 |
| 32 | Chronic hepatic failure (HP:0100626) | 2.46779686 |
| 33 | Attenuation of retinal blood vessels (HP:0007843) | 2.46727392 |
| 34 | Dyskinesia (HP:0100660) | 2.46608135 |
| 35 | Hypoplasia of the uterus (HP:0000013) | 2.44392919 |
| 36 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.42386112 |
| 37 | Hypoplasia of the fovea (HP:0007750) | 2.42386112 |
| 38 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.41697042 |
| 39 | Pachygyria (HP:0001302) | 2.40034823 |
| 40 | Abnormality of midbrain morphology (HP:0002418) | 2.38569524 |
| 41 | Molar tooth sign on MRI (HP:0002419) | 2.38569524 |
| 42 | Prominent supraorbital ridges (HP:0000336) | 2.36441143 |
| 43 | Type II lissencephaly (HP:0007260) | 2.35595741 |
| 44 | Abnormal drinking behavior (HP:0030082) | 2.34501541 |
| 45 | Polydipsia (HP:0001959) | 2.34501541 |
| 46 | Tubular atrophy (HP:0000092) | 2.29986783 |
| 47 | Supernumerary spleens (HP:0009799) | 2.27233792 |
| 48 | Action tremor (HP:0002345) | 2.27023182 |
| 49 | Congenital hepatic fibrosis (HP:0002612) | 2.26662890 |
| 50 | Hypothermia (HP:0002045) | 2.25664282 |
| 51 | Medial flaring of the eyebrow (HP:0010747) | 2.24497361 |
| 52 | Ulnar claw (HP:0001178) | 2.24263783 |
| 53 | Hyperglycemia (HP:0003074) | 2.23448068 |
| 54 | Spastic paraparesis (HP:0002313) | 2.21017480 |
| 55 | Abnormal biliary tract physiology (HP:0012439) | 2.19134680 |
| 56 | Bile duct proliferation (HP:0001408) | 2.19134680 |
| 57 | Patellar aplasia (HP:0006443) | 2.17238188 |
| 58 | Methylmalonic aciduria (HP:0012120) | 2.16819760 |
| 59 | Increased corneal curvature (HP:0100692) | 2.16483327 |
| 60 | Keratoconus (HP:0000563) | 2.16483327 |
| 61 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.16447962 |
| 62 | Nephronophthisis (HP:0000090) | 2.15784779 |
| 63 | Progressive macrocephaly (HP:0004481) | 2.15739061 |
| 64 | Breast hypoplasia (HP:0003187) | 2.14320749 |
| 65 | Increased hepatocellular lipid droplets (HP:0006565) | 2.11358231 |
| 66 | Acute encephalopathy (HP:0006846) | 2.10418142 |
| 67 | Cystic liver disease (HP:0006706) | 2.09573255 |
| 68 | Abnormality of saccadic eye movements (HP:0000570) | 2.09280388 |
| 69 | Dry hair (HP:0011359) | 2.08486768 |
| 70 | Lipid accumulation in hepatocytes (HP:0006561) | 2.07348240 |
| 71 | Decreased circulating renin level (HP:0003351) | 2.06343009 |
| 72 | Congenital malformation of the right heart (HP:0011723) | 2.06245920 |
| 73 | Double outlet right ventricle (HP:0001719) | 2.06245920 |
| 74 | Hypomagnesemia (HP:0002917) | 2.04790676 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 2.04111447 |
| 76 | Facial diplegia (HP:0001349) | 2.03274875 |
| 77 | Spinal muscular atrophy (HP:0007269) | 2.03211453 |
| 78 | Inability to walk (HP:0002540) | 2.03194873 |
| 79 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.03002166 |
| 80 | Mitochondrial inheritance (HP:0001427) | 2.01875057 |
| 81 | Optic disc pallor (HP:0000543) | 2.00302855 |
| 82 | Degeneration of anterior horn cells (HP:0002398) | 1.99879324 |
| 83 | Abnormality of the anterior horn cell (HP:0006802) | 1.99879324 |
| 84 | Cerebral edema (HP:0002181) | 1.99598242 |
| 85 | Tubulointerstitial nephritis (HP:0001970) | 1.98656270 |
| 86 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.98080036 |
| 87 | Ketoacidosis (HP:0001993) | 1.96726521 |
| 88 | Polyuria (HP:0000103) | 1.95131612 |
| 89 | Glycosuria (HP:0003076) | 1.94525837 |
| 90 | Abnormality of urine glucose concentration (HP:0011016) | 1.94525837 |
| 91 | Protruding tongue (HP:0010808) | 1.94279846 |
| 92 | Progressive inability to walk (HP:0002505) | 1.93752253 |
| 93 | Increased CSF lactate (HP:0002490) | 1.92266995 |
| 94 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.91712827 |
| 95 | Hypoplasia of the brainstem (HP:0002365) | 1.91712827 |
| 96 | Tubulointerstitial abnormality (HP:0001969) | 1.91184774 |
| 97 | Abnormality of the fovea (HP:0000493) | 1.89227478 |
| 98 | Postural tremor (HP:0002174) | 1.88265616 |
| 99 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.85223178 |
| 100 | Chronic bronchitis (HP:0004469) | 1.84673743 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 4.14499488 |
| 2 | WNK4 | 3.79846512 |
| 3 | GRK1 | 3.01808721 |
| 4 | ADRBK2 | 2.98794151 |
| 5 | VRK2 | 2.35673085 |
| 6 | MAP4K2 | 2.31071427 |
| 7 | TNIK | 2.27962729 |
| 8 | BMPR1B | 2.17846814 |
| 9 | MAP3K4 | 2.10631487 |
| 10 | WNK3 | 1.98953889 |
| 11 | MARK1 | 1.98343053 |
| 12 | DAPK2 | 1.83687983 |
| 13 | INSRR | 1.80244100 |
| 14 | CASK | 1.79176795 |
| 15 | NUAK1 | 1.77546260 |
| 16 | WNK1 | 1.73803707 |
| 17 | EIF2AK3 | 1.69513724 |
| 18 | PINK1 | 1.69428151 |
| 19 | CAMKK2 | 1.57255078 |
| 20 | MAPK13 | 1.56782547 |
| 21 | BRSK2 | 1.55659233 |
| 22 | TIE1 | 1.51338555 |
| 23 | EPHA4 | 1.49150779 |
| 24 | MKNK1 | 1.47144911 |
| 25 | PRKCG | 1.40769698 |
| 26 | CSNK1G3 | 1.36521432 |
| 27 | MAP2K6 | 1.33156976 |
| 28 | PASK | 1.29113010 |
| 29 | PAK3 | 1.28184673 |
| 30 | TGFBR1 | 1.26806802 |
| 31 | CSNK1G2 | 1.24169080 |
| 32 | ACVR1B | 1.23196894 |
| 33 | CSNK1G1 | 1.19291139 |
| 34 | PRKCE | 1.18811434 |
| 35 | CCNB1 | 1.17812515 |
| 36 | CAMK2D | 1.16160961 |
| 37 | BMX | 1.14133939 |
| 38 | PHKG1 | 1.12144221 |
| 39 | PHKG2 | 1.12144221 |
| 40 | MST4 | 1.11404369 |
| 41 | VRK1 | 1.08477317 |
| 42 | TLK1 | 1.08114105 |
| 43 | CAMKK1 | 1.07683962 |
| 44 | TAOK3 | 1.07312729 |
| 45 | TNK2 | 1.06611848 |
| 46 | DYRK2 | 1.05835653 |
| 47 | ADRBK1 | 0.93541116 |
| 48 | MAPKAPK5 | 0.93538607 |
| 49 | PLK2 | 0.92790867 |
| 50 | UHMK1 | 0.91565637 |
| 51 | CSNK1A1L | 0.88735488 |
| 52 | ZAK | 0.88349867 |
| 53 | PIK3CA | 0.84660527 |
| 54 | ABL2 | 0.83973414 |
| 55 | NEK1 | 0.83583370 |
| 56 | TAF1 | 0.82756307 |
| 57 | PRKCH | 0.79266361 |
| 58 | STK11 | 0.79125922 |
| 59 | DDR2 | 0.78943244 |
| 60 | TRPM7 | 0.74019845 |
| 61 | CAMK2A | 0.71602369 |
| 62 | OXSR1 | 0.69919820 |
| 63 | MKNK2 | 0.69124053 |
| 64 | PRKCA | 0.62057042 |
| 65 | CDK3 | 0.60122392 |
| 66 | OBSCN | 0.59071577 |
| 67 | MAP2K7 | 0.57556278 |
| 68 | MAP2K4 | 0.56669242 |
| 69 | EPHB2 | 0.55578225 |
| 70 | PRKACA | 0.55103893 |
| 71 | PRKACB | 0.53833255 |
| 72 | FGFR2 | 0.53230585 |
| 73 | TYRO3 | 0.52363361 |
| 74 | RPS6KA5 | 0.50989627 |
| 75 | PRKCQ | 0.50726843 |
| 76 | STK39 | 0.50469536 |
| 77 | PTK6 | 0.50054706 |
| 78 | CSNK1A1 | 0.49777571 |
| 79 | DYRK1B | 0.49239056 |
| 80 | FES | 0.49099384 |
| 81 | PRKCZ | 0.48872268 |
| 82 | PLK3 | 0.48380877 |
| 83 | FER | 0.45107329 |
| 84 | CAMK1D | 0.44888117 |
| 85 | NTRK2 | 0.43550549 |
| 86 | MINK1 | 0.43003945 |
| 87 | PRKACG | 0.40069955 |
| 88 | MARK3 | 0.38382707 |
| 89 | SGK1 | 0.38060207 |
| 90 | PTK2B | 0.37174224 |
| 91 | SRPK1 | 0.37104546 |
| 92 | CAMK2B | 0.36588363 |
| 93 | ATM | 0.36372551 |
| 94 | PRKCB | 0.36098660 |
| 95 | GSK3A | 0.35798242 |
| 96 | PLK1 | 0.35672234 |
| 97 | CSNK1D | 0.33793088 |
| 98 | MAPK7 | 0.32275723 |
| 99 | IKBKB | 0.32096624 |
| 100 | SGK2 | 0.30302293 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Homologous recombination_Homo sapiens_hsa03440 | 2.72341831 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.67577730 |
| 3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.40110867 |
| 4 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.38333563 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 2.32328791 |
| 6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.32185717 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.24919255 |
| 8 | Taste transduction_Homo sapiens_hsa04742 | 2.22225552 |
| 9 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.15253171 |
| 10 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.12268898 |
| 11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.06641544 |
| 12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.00497953 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 1.98341601 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.94608894 |
| 15 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.83816596 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.82157957 |
| 17 | Nicotine addiction_Homo sapiens_hsa05033 | 1.79232085 |
| 18 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.73067885 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.71638637 |
| 20 | Ribosome_Homo sapiens_hsa03010 | 1.67170187 |
| 21 | Long-term depression_Homo sapiens_hsa04730 | 1.65119442 |
| 22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.64927946 |
| 23 | ABC transporters_Homo sapiens_hsa02010 | 1.60641788 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.59517734 |
| 25 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.57987798 |
| 26 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.54820378 |
| 27 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.52471650 |
| 28 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.50564568 |
| 29 | Asthma_Homo sapiens_hsa05310 | 1.39752754 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.38990608 |
| 31 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.36097189 |
| 32 | Huntingtons disease_Homo sapiens_hsa05016 | 1.33843192 |
| 33 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.28955850 |
| 34 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.28931275 |
| 35 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.27953079 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.27919478 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.27494840 |
| 38 | Proteasome_Homo sapiens_hsa03050 | 1.26421508 |
| 39 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.25707497 |
| 40 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.14068547 |
| 41 | Insulin secretion_Homo sapiens_hsa04911 | 1.12732263 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.09419549 |
| 43 | Protein export_Homo sapiens_hsa03060 | 1.09265842 |
| 44 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.08502812 |
| 45 | Alzheimers disease_Homo sapiens_hsa05010 | 1.05906508 |
| 46 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.05866014 |
| 47 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.05592157 |
| 48 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.01782984 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.99863759 |
| 50 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.97834150 |
| 51 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.97782536 |
| 52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.95881977 |
| 53 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.95796126 |
| 54 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.94079947 |
| 55 | GABAergic synapse_Homo sapiens_hsa04727 | 0.92137716 |
| 56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.91477269 |
| 57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.84542748 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83089836 |
| 59 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.82515559 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.78250916 |
| 61 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.77534939 |
| 62 | RNA degradation_Homo sapiens_hsa03018 | 0.77285572 |
| 63 | Mismatch repair_Homo sapiens_hsa03430 | 0.75271819 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.74942095 |
| 65 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.74758577 |
| 66 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.74057877 |
| 67 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.73182306 |
| 68 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.71929180 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71564595 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.70148278 |
| 71 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.69923206 |
| 72 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.69120192 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.68974456 |
| 74 | Morphine addiction_Homo sapiens_hsa05032 | 0.67079155 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65091194 |
| 76 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.64842287 |
| 77 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.64194883 |
| 78 | Lysine degradation_Homo sapiens_hsa00310 | 0.62347176 |
| 79 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61670069 |
| 80 | Base excision repair_Homo sapiens_hsa03410 | 0.59635488 |
| 81 | Histidine metabolism_Homo sapiens_hsa00340 | 0.55471968 |
| 82 | Salivary secretion_Homo sapiens_hsa04970 | 0.55126584 |
| 83 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.53706046 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51068154 |
| 85 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50580928 |
| 86 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.49550894 |
| 87 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.48517329 |
| 88 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.47789628 |
| 89 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.47122102 |
| 90 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.46850305 |
| 91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.45935713 |
| 92 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.45536488 |
| 93 | Other glycan degradation_Homo sapiens_hsa00511 | 0.43766528 |
| 94 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.38852043 |
| 95 | Circadian entrainment_Homo sapiens_hsa04713 | 0.38648321 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.37225958 |
| 97 | Mineral absorption_Homo sapiens_hsa04978 | 0.35332893 |
| 98 | Allograft rejection_Homo sapiens_hsa05330 | 0.34311394 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.34133373 |
| 100 | DNA replication_Homo sapiens_hsa03030 | 0.33238720 |

