RBM18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.80422610
2polyketide metabolic process (GO:0030638)5.35844147
3doxorubicin metabolic process (GO:0044598)5.35844147
4daunorubicin metabolic process (GO:0044597)5.35844147
5ribonucleoprotein complex disassembly (GO:0032988)4.16017669
6protein-cofactor linkage (GO:0018065)4.04920212
7platelet dense granule organization (GO:0060155)3.84423029
8nonmotile primary cilium assembly (GO:0035058)3.84241942
9inositol phosphate catabolic process (GO:0071545)3.80987753
10motile cilium assembly (GO:0044458)3.71011136
11negative regulation of meiosis (GO:0045835)3.55738493
12synaptic vesicle docking involved in exocytosis (GO:0016081)3.52853625
13inositol phosphate dephosphorylation (GO:0046855)3.51005834
14phosphorylated carbohydrate dephosphorylation (GO:0046838)3.51005834
15maturation of 5.8S rRNA (GO:0000460)3.44451711
16organelle disassembly (GO:1903008)3.36390514
17lactate metabolic process (GO:0006089)3.31676196
18regulation of acyl-CoA biosynthetic process (GO:0050812)3.27513442
19pigment granule transport (GO:0051904)3.24005477
20substrate-independent telencephalic tangential migration (GO:0021826)3.21043609
21substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.21043609
22striatum development (GO:0021756)3.21033118
23regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.19146712
24establishment of pigment granule localization (GO:0051905)3.15650028
25protein deneddylation (GO:0000338)3.14575070
26cerebral cortex radially oriented cell migration (GO:0021799)3.10295324
27chaperone-mediated protein transport (GO:0072321)3.10204259
28regulation of female gonad development (GO:2000194)3.09032612
29regulation of cofactor metabolic process (GO:0051193)3.08651363
30regulation of coenzyme metabolic process (GO:0051196)3.08651363
31pyrimidine nucleobase catabolic process (GO:0006208)3.07443124
32pigment granule localization (GO:0051875)3.06618298
33aminoglycoside antibiotic metabolic process (GO:0030647)3.06143566
34neuron cell-cell adhesion (GO:0007158)3.04314763
35DNA integration (GO:0015074)3.03790652
36water-soluble vitamin biosynthetic process (GO:0042364)3.03300631
37anterograde synaptic vesicle transport (GO:0048490)3.02763772
38positive regulation of mitochondrial fission (GO:0090141)3.00147162
39regulation of meiosis (GO:0040020)2.99937037
40piRNA metabolic process (GO:0034587)2.99559719
41mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.98011940
42histone H2A acetylation (GO:0043968)2.97451880
43respiratory chain complex IV assembly (GO:0008535)2.96978638
44positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.96916302
45mitochondrial respiratory chain complex I assembly (GO:0032981)2.95945306
46NADH dehydrogenase complex assembly (GO:0010257)2.95945306
47mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.95945306
48neural tube formation (GO:0001841)2.94625302
49cullin deneddylation (GO:0010388)2.93529526
50regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.92112601
51ribosome assembly (GO:0042255)2.91043910
52regulation of cAMP-dependent protein kinase activity (GO:2000479)2.89359358
53regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.85017486
54polyol catabolic process (GO:0046174)2.84770608
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.82911206
56protein K11-linked deubiquitination (GO:0035871)2.82748984
57succinate metabolic process (GO:0006105)2.82084552
58neuronal action potential propagation (GO:0019227)2.81778630
59regulation of cellular amino acid metabolic process (GO:0006521)2.81715531
60positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.81319884
61protein complex biogenesis (GO:0070271)2.80791103
62G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.78772871
63energy homeostasis (GO:0097009)2.77189268
64righting reflex (GO:0060013)2.75724452
65regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.75528532
66DNA methylation involved in gamete generation (GO:0043046)2.74881965
67ganglion development (GO:0061548)2.74361799
68mitochondrial respiratory chain complex assembly (GO:0033108)2.72842785
69protein targeting to mitochondrion (GO:0006626)2.71669181
70DNA catabolic process, exonucleolytic (GO:0000738)2.70469125
71protein localization to mitochondrion (GO:0070585)2.70338258
72anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.69924783
73transcription elongation from RNA polymerase III promoter (GO:0006385)2.69395494
74termination of RNA polymerase III transcription (GO:0006386)2.69395494
75DNA double-strand break processing (GO:0000729)2.68677310
76regulation of cilium movement (GO:0003352)2.68166791
77neurotransmitter-gated ion channel clustering (GO:0072578)2.68094408
78negative regulation of meiotic cell cycle (GO:0051447)2.66065115
79positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.65450278
80positive regulation of neurotransmitter secretion (GO:0001956)2.64760534
81regulation of penile erection (GO:0060405)2.64566710
82postsynaptic membrane organization (GO:0001941)2.63502991
837-methylguanosine mRNA capping (GO:0006370)2.62822790
84positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.62714714
85protein localization to synapse (GO:0035418)2.61951878
86atrial cardiac muscle cell action potential (GO:0086014)2.61649249
87melanosome transport (GO:0032402)2.60273671
88establishment of protein localization to mitochondrion (GO:0072655)2.59861830
89pyrimidine dimer repair (GO:0006290)2.59171147
90C-terminal protein amino acid modification (GO:0018410)2.58993303
91negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.58547731
92positive regulation of ligase activity (GO:0051351)2.57960599
93male meiosis (GO:0007140)2.57767021
94intraciliary transport (GO:0042073)2.55595072
95ubiquinone metabolic process (GO:0006743)2.55311994
96protein localization to cilium (GO:0061512)2.55285852
97establishment of protein localization to mitochondrial membrane (GO:0090151)2.54913787
98startle response (GO:0001964)2.54813666
99nucleobase catabolic process (GO:0046113)2.54781252
100nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.54749198
101establishment of melanosome localization (GO:0032401)2.54555190
102negative regulation of phosphoprotein phosphatase activity (GO:0032515)2.53713700
103positive regulation of neurotransmitter transport (GO:0051590)2.53696008
1047-methylguanosine RNA capping (GO:0009452)2.53525728
105RNA capping (GO:0036260)2.53525728
106regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.53504676
107DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.53207517
108viral protein processing (GO:0019082)2.53050674
109gamma-aminobutyric acid transport (GO:0015812)2.52697262
110inner ear receptor stereocilium organization (GO:0060122)2.52227514
111extracellular negative regulation of signal transduction (GO:1900116)2.52066077
112extracellular regulation of signal transduction (GO:1900115)2.52066077
113auditory receptor cell stereocilium organization (GO:0060088)2.51798821
114positive regulation of TOR signaling (GO:0032008)2.51562601
115signal peptide processing (GO:0006465)2.50499885
116melanosome localization (GO:0032400)2.50443372
117vocalization behavior (GO:0071625)2.50414404
118positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.49702758
119protein localization to microtubule cytoskeleton (GO:0072698)2.49237723
120exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.49151952
121negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.48800744
122negative regulation of ligase activity (GO:0051352)2.48800744
123histone mRNA metabolic process (GO:0008334)2.48749880
124lipid particle organization (GO:0034389)2.48540283
125glycosphingolipid biosynthetic process (GO:0006688)2.48086400
126synaptic vesicle exocytosis (GO:0016079)2.47873745
127dentate gyrus development (GO:0021542)2.46144514
128positive regulation of protein homodimerization activity (GO:0090073)2.44198350
129regulation of synaptic vesicle exocytosis (GO:2000300)2.43987114
130transcription elongation from RNA polymerase I promoter (GO:0006362)2.43920406
131signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.43384063
132intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.43384063
133regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.43308077
134mitochondrial RNA metabolic process (GO:0000959)2.43278754
135signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.42618593
136signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.42618593
137signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.42618593
138regulation of meiotic cell cycle (GO:0051445)2.42256273
139positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.41686362
140mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.41686362
141regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.41672567
142C-terminal protein lipidation (GO:0006501)2.41660577
143positive regulation of glycolytic process (GO:0045821)2.41489551
144cilium assembly (GO:0042384)2.41256159
145dendrite development (GO:0016358)2.41241728
146signal transduction involved in cell cycle checkpoint (GO:0072395)2.40906007
147de novo protein folding (GO:0006458)2.40279427
148regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.39561986
149regulation of sulfur metabolic process (GO:0042762)2.39445552
150telomere maintenance via telomerase (GO:0007004)2.39414712
151centriole assembly (GO:0098534)2.38838903
152negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.38529460
153protein targeting to Golgi (GO:0000042)2.38401095
154transferrin transport (GO:0033572)2.38372983
155ubiquinone biosynthetic process (GO:0006744)2.38278272
156transcription from mitochondrial promoter (GO:0006390)2.36204251
157behavioral response to ethanol (GO:0048149)2.35706620
158negative regulation of synaptic transmission, GABAergic (GO:0032229)2.35267029
159presynaptic membrane assembly (GO:0097105)2.34734186
160regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.34497910
161regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.34497910
162protein K11-linked ubiquitination (GO:0070979)2.34236725
163protein localization to cytoskeleton (GO:0044380)2.34103085
164photoreceptor cell maintenance (GO:0045494)2.32860287
165microtubule nucleation (GO:0007020)2.32375701
166positive regulation of meiosis (GO:0045836)2.31207960
167vesicle localization (GO:0051648)2.30286125
168urinary tract smooth muscle contraction (GO:0014848)2.29821982
169serotonin receptor signaling pathway (GO:0007210)2.27876745
170replicative senescence (GO:0090399)2.27746914
171trivalent inorganic cation transport (GO:0072512)2.27568408
172ferric iron transport (GO:0015682)2.27568408
173regulation of synaptic vesicle transport (GO:1902803)2.25443761
174cilium organization (GO:0044782)2.25238388
175mechanosensory behavior (GO:0007638)2.24250012
176microtubule depolymerization (GO:0007019)2.23309117
177positive regulation of synapse assembly (GO:0051965)2.22028981
178axonemal dynein complex assembly (GO:0070286)2.21328136
179protein neddylation (GO:0045116)2.19984076
180negative regulation of mast cell activation (GO:0033004)2.19593843
181synaptic transmission, glutamatergic (GO:0035249)2.19009823
182mitochondrial fission (GO:0000266)2.18461484
183photoreceptor cell development (GO:0042461)2.18295875
184response to pheromone (GO:0019236)2.17631598
185regulation of synapse maturation (GO:0090128)2.17397822
186auditory behavior (GO:0031223)2.17014956
187muscle organ morphogenesis (GO:0048644)2.16839651
188protein K6-linked ubiquitination (GO:0085020)2.16710009

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.46629809
2EZH2_22144423_ChIP-Seq_EOC_Human3.12071987
3EST1_17652178_ChIP-ChIP_JURKAT_Human2.91305056
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.80457500
5POU3F2_20337985_ChIP-ChIP_501MEL_Human2.71752129
6TAF15_26573619_Chip-Seq_HEK293_Human2.69073274
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.68759225
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.63775227
9* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.59641938
10* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.57032754
11ELK1_19687146_ChIP-ChIP_HELA_Human2.53467798
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.50925559
13BMI1_23680149_ChIP-Seq_NPCS_Mouse2.24418821
14RNF2_27304074_Chip-Seq_NSC_Mouse2.10488982
15VDR_23849224_ChIP-Seq_CD4+_Human2.08773325
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.06247964
17* FUS_26573619_Chip-Seq_HEK293_Human2.03966569
18P300_19829295_ChIP-Seq_ESCs_Human2.02284718
19CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02175259
20VDR_22108803_ChIP-Seq_LS180_Human1.95343694
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.94363755
22ETS1_20019798_ChIP-Seq_JURKAT_Human1.91282932
23SMAD_19615063_ChIP-ChIP_OVARY_Human1.89212266
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.89026047
25CREB1_15753290_ChIP-ChIP_HEK293T_Human1.88041324
26CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.84039372
27* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.83515464
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.81315268
29PADI4_21655091_ChIP-ChIP_MCF-7_Human1.78277395
30CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76937031
31* EWS_26573619_Chip-Seq_HEK293_Human1.76508556
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.76424218
33EZH2_27304074_Chip-Seq_ESCs_Mouse1.74943153
34IGF1R_20145208_ChIP-Seq_DFB_Human1.74895039
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.73129855
36SALL1_21062744_ChIP-ChIP_HESCs_Human1.72000155
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71333142
38SMAD4_21799915_ChIP-Seq_A2780_Human1.70846368
39RBPJ_22232070_ChIP-Seq_NCS_Mouse1.69359753
40JARID2_20064375_ChIP-Seq_MESCs_Mouse1.63663713
41SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.63161544
42RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.61993688
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.60659694
44CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.60251304
45EED_16625203_ChIP-ChIP_MESCs_Mouse1.59809100
46TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.58289361
47OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53601159
48SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.53363747
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52772321
50CBP_20019798_ChIP-Seq_JUKART_Human1.52772321
51NANOG_18555785_Chip-Seq_ESCs_Mouse1.52064539
52* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.50919744
53TOP2B_26459242_ChIP-Seq_MCF-7_Human1.50772669
54FOXP3_21729870_ChIP-Seq_TREG_Human1.49306700
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.49123986
56FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.48739609
57SRF_21415370_ChIP-Seq_HL-1_Mouse1.45685696
58SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.44910416
59AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.44634776
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.44412399
61SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44153242
62DCP1A_22483619_ChIP-Seq_HELA_Human1.43453180
63NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.43131811
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.42950509
65PIAS1_25552417_ChIP-Seq_VCAP_Human1.42778948
66SUZ12_27294783_Chip-Seq_NPCs_Mouse1.42648338
67ER_23166858_ChIP-Seq_MCF-7_Human1.41551490
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.40264547
69SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.39975312
70PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39022816
71E2F1_18555785_Chip-Seq_ESCs_Mouse1.37586149
72EZH2_18974828_ChIP-Seq_MESCs_Mouse1.35061139
73RNF2_18974828_ChIP-Seq_MESCs_Mouse1.35061139
74CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35040682
75SUZ12_18555785_Chip-Seq_ESCs_Mouse1.34693204
76PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.33348355
77ELF1_17652178_ChIP-ChIP_JURKAT_Human1.32322535
78REST_21632747_ChIP-Seq_MESCs_Mouse1.32123171
79* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.31820254
80KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.31765679
81AR_21572438_ChIP-Seq_LNCaP_Human1.30527511
82P53_22387025_ChIP-Seq_ESCs_Mouse1.29638582
83UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.29375038
84NFE2_27457419_Chip-Seq_LIVER_Mouse1.28882587
85MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28877545
86STAT3_18555785_Chip-Seq_ESCs_Mouse1.28051605
87TP53_22573176_ChIP-Seq_HFKS_Human1.27797241
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27270717
89JUN_21703547_ChIP-Seq_K562_Human1.27210448
90* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.26920189
91MYC_18940864_ChIP-ChIP_HL60_Human1.26889988
92EZH2_27294783_Chip-Seq_NPCs_Mouse1.26791651
93* AR_25329375_ChIP-Seq_VCAP_Human1.26339061
94* CMYC_18555785_Chip-Seq_ESCs_Mouse1.26310152
95YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26192223
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25933489
97JARID2_20075857_ChIP-Seq_MESCs_Mouse1.24883477
98E2F4_17652178_ChIP-ChIP_JURKAT_Human1.24563095
99RNF2_27304074_Chip-Seq_ESCs_Mouse1.23654187
100MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.22647411
101SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.22013021
102* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.21607881
103NOTCH1_21737748_ChIP-Seq_TLL_Human1.20933878
104GABP_19822575_ChIP-Seq_HepG2_Human1.20929896
105HTT_18923047_ChIP-ChIP_STHdh_Human1.20328393
106STAT3_23295773_ChIP-Seq_U87_Human1.19623118
107NANOG_19829295_ChIP-Seq_ESCs_Human1.19063447
108SOX2_19829295_ChIP-Seq_ESCs_Human1.19063447
109THAP11_20581084_ChIP-Seq_MESCs_Mouse1.17940078
110MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17811692
111NMYC_18555785_Chip-Seq_ESCs_Mouse1.17724631
112TAL1_26923725_Chip-Seq_HPCs_Mouse1.16820025
113CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.15546351
114* SOX2_18555785_Chip-Seq_ESCs_Mouse1.15239707
115RUNX2_22187159_ChIP-Seq_PCA_Human1.14447279
116EZH2_27294783_Chip-Seq_ESCs_Mouse1.13603112
117TCF4_23295773_ChIP-Seq_U87_Human1.12582270
118KLF5_20875108_ChIP-Seq_MESCs_Mouse1.12543418
119NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12020309
120P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11235630
121ZNF274_21170338_ChIP-Seq_K562_Hela1.09876284
122PRDM14_20953172_ChIP-Seq_ESCs_Human1.08663761
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08638941
124TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08638941
125* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08599022
126HOXB4_20404135_ChIP-ChIP_EML_Mouse1.08035276
127SOX9_26525672_Chip-Seq_HEART_Mouse1.07896402
128TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07564760
129KDM2B_26808549_Chip-Seq_REH_Human1.06554484
130* P300_18555785_Chip-Seq_ESCs_Mouse1.06409237
131SALL4_22934838_ChIP-ChIP_CD34+_Human1.05373661
132ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.04944613
133* OCT4_18555785_Chip-Seq_ESCs_Mouse1.03398502
134SUZ12_27294783_Chip-Seq_ESCs_Mouse1.02462738
135TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.01913244
136SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.01769414
137GABP_17652178_ChIP-ChIP_JURKAT_Human1.00927597
138EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00881322
139CRX_20693478_ChIP-Seq_RETINA_Mouse0.99872428
140NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96123475
141NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96123475
142BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.94592173
143BCAT_22108803_ChIP-Seq_LS180_Human0.94082065
144HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.93934072

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009697_abnormal_copulation3.05642411
2MP0006292_abnormal_olfactory_placode2.94311116
3MP0001984_abnormal_olfaction2.91705601
4MP0001188_hyperpigmentation2.67631886
5MP0005646_abnormal_pituitary_gland2.51712702
6MP0000566_synostosis2.43290663
7MP0003880_abnormal_central_pattern2.37724456
8MP0005171_absent_coat_pigmentation2.32231184
9MP0005645_abnormal_hypothalamus_physiol2.30547069
10MP0001529_abnormal_vocalization2.28688764
11MP0003787_abnormal_imprinting2.24132804
12MP0003221_abnormal_cardiomyocyte_apopto2.13914648
13MP0002822_catalepsy2.13542071
14MP0002102_abnormal_ear_morphology2.11016472
15MP0002234_abnormal_pharynx_morphology2.10312336
16MP0008877_abnormal_DNA_methylation2.09818250
17MP0008789_abnormal_olfactory_epithelium2.09253410
18MP0006276_abnormal_autonomic_nervous2.06438429
19MP0009780_abnormal_chondrocyte_physiolo1.93739606
20MP0001986_abnormal_taste_sensitivity1.89256968
21MP0000749_muscle_degeneration1.88812607
22MP0002736_abnormal_nociception_after1.87388865
23MP0005084_abnormal_gallbladder_morpholo1.85679996
24MP0003646_muscle_fatigue1.84794787
25MP0002734_abnormal_mechanical_nocicepti1.84538645
26MP0005394_taste/olfaction_phenotype1.82956493
27MP0005499_abnormal_olfactory_system1.82956493
28MP0003786_premature_aging1.78573185
29MP0004142_abnormal_muscle_tone1.78491832
30MP0006036_abnormal_mitochondrial_physio1.77370460
31MP0001968_abnormal_touch/_nociception1.76860353
32MP0010386_abnormal_urinary_bladder1.74742128
33MP0008995_early_reproductive_senescence1.72950924
34MP0003121_genomic_imprinting1.64539332
35MP0003122_maternal_imprinting1.63230224
36MP0004859_abnormal_synaptic_plasticity1.63011241
37MP0003635_abnormal_synaptic_transmissio1.58118392
38MP0005187_abnormal_penis_morphology1.56184393
39MP0001486_abnormal_startle_reflex1.53605053
40MP0006035_abnormal_mitochondrial_morpho1.52090775
41MP0002572_abnormal_emotion/affect_behav1.51893050
42MP0008004_abnormal_stomach_pH1.51472908
43MP0001764_abnormal_homeostasis1.51378343
44MP0002184_abnormal_innervation1.51305603
45MP0009745_abnormal_behavioral_response1.49861613
46MP0000678_abnormal_parathyroid_gland1.46368216
47MP0002063_abnormal_learning/memory/cond1.45193810
48MP0002938_white_spotting1.44074462
49MP0006072_abnormal_retinal_apoptosis1.43730418
50MP0004147_increased_porphyrin_level1.42992069
51MP0002909_abnormal_adrenal_gland1.42431023
52MP0000778_abnormal_nervous_system1.42187942
53MP0002735_abnormal_chemical_nociception1.39961505
54MP0003718_maternal_effect1.38476925
55MP0005551_abnormal_eye_electrophysiolog1.37864497
56MP0004270_analgesia1.36901457
57MP0001905_abnormal_dopamine_level1.35632320
58MP0009046_muscle_twitch1.35505209
59MP0000631_abnormal_neuroendocrine_gland1.34600606
60MP0002557_abnormal_social/conspecific_i1.34149572
61MP0004145_abnormal_muscle_electrophysio1.34005289
62MP0003879_abnormal_hair_cell1.31290314
63MP0005423_abnormal_somatic_nervous1.29810111
64MP0002272_abnormal_nervous_system1.29641927
65MP0004084_abnormal_cardiac_muscle1.28492069
66MP0001485_abnormal_pinna_reflex1.25015191
67MP0002638_abnormal_pupillary_reflex1.23930550
68MP0002067_abnormal_sensory_capabilities1.22178113
69MP0002064_seizures1.21356541
70MP0003950_abnormal_plasma_membrane1.19435433
71MP0010030_abnormal_orbit_morphology1.19315181
72MP0003890_abnormal_embryonic-extraembry1.18846401
73MP0005386_behavior/neurological_phenoty1.17812044
74MP0004924_abnormal_behavior1.17812044
75MP0004036_abnormal_muscle_relaxation1.16769159
76MP0000751_myopathy1.16164582
77MP0003011_delayed_dark_adaptation1.15619970
78MP0004742_abnormal_vestibular_system1.15540383
79MP0002332_abnormal_exercise_endurance1.15483688
80MP0001502_abnormal_circadian_rhythm1.14815572
81MP0000372_irregular_coat_pigmentation1.13388482
82MP0003806_abnormal_nucleotide_metabolis1.13075845
83MP0000427_abnormal_hair_cycle1.12180941
84MP0002751_abnormal_autonomic_nervous1.11176402
85MP0004484_altered_response_of1.09937606
86MP0004134_abnormal_chest_morphology1.08602315
87MP0010094_abnormal_chromosome_stability1.07625015
88MP0002269_muscular_atrophy1.05816240
89MP0003567_abnormal_fetal_cardiomyocyte1.05105013
90MP0000049_abnormal_middle_ear1.04395763
91MP0005620_abnormal_muscle_contractility1.03815393
92MP0009250_abnormal_appendicular_skeleto1.02657041
93MP0000026_abnormal_inner_ear1.02434435
94MP0002106_abnormal_muscle_physiology1.01354933
95MP0004782_abnormal_surfactant_physiolog1.00238439
96MP0003656_abnormal_erythrocyte_physiolo1.00198016
97MP0001119_abnormal_female_reproductive0.99914155
98MP0000516_abnormal_urinary_system0.98731291
99MP0005367_renal/urinary_system_phenotyp0.98731291
100MP0004233_abnormal_muscle_weight0.97214812
101MP0008058_abnormal_DNA_repair0.97152014
102MP0001963_abnormal_hearing_physiology0.95454818
103MP0001177_atelectasis0.94149666
104MP0008260_abnormal_autophagy0.92385054
105MP0002876_abnormal_thyroid_physiology0.92199441
106MP0005389_reproductive_system_phenotype0.91933845
107MP0000647_abnormal_sebaceous_gland0.91168650
108MP0003137_abnormal_impulse_conducting0.91118519
109MP0001970_abnormal_pain_threshold0.90667653
110MP0005377_hearing/vestibular/ear_phenot0.90511345
111MP0003878_abnormal_ear_physiology0.90511345
112MP0005253_abnormal_eye_physiology0.89738052
113MP0001440_abnormal_grooming_behavior0.89525488
114MP0004043_abnormal_pH_regulation0.89125259
115MP0002752_abnormal_somatic_nervous0.88685672
116MP0002210_abnormal_sex_determination0.88561485
117MP0002972_abnormal_cardiac_muscle0.88434628
118MP0008775_abnormal_heart_ventricle0.87837464
119MP0001919_abnormal_reproductive_system0.86460073
120MP0000465_gastrointestinal_hemorrhage0.85971795
121MP0002653_abnormal_ependyma_morphology0.84677920
122MP0004957_abnormal_blastocyst_morpholog0.83815177
123MP0005503_abnormal_tendon_morphology0.83093933
124MP0004085_abnormal_heartbeat0.82910758
125MP0002882_abnormal_neuron_morphology0.82740143
126MP0004811_abnormal_neuron_physiology0.82309961
127MP0003183_abnormal_peptide_metabolism0.81471145
128MP0000358_abnormal_cell_content/0.81406745
129MP0002277_abnormal_respiratory_mucosa0.79860573
130MP0001501_abnormal_sleep_pattern0.79779901
131MP0005310_abnormal_salivary_gland0.79365735
132MP0000015_abnormal_ear_pigmentation0.79002579
133MP0005408_hypopigmentation0.78038471
134MP0000639_abnormal_adrenal_gland0.77544800
135MP0002177_abnormal_outer_ear0.76683348
136MP0003186_abnormal_redox_activity0.76566090
137MP0004215_abnormal_myocardial_fiber0.76267478
138MP0005248_abnormal_Harderian_gland0.75785098
139MP0002160_abnormal_reproductive_system0.75562151
140MP0001270_distended_abdomen0.74608954
141MP0003385_abnormal_body_wall0.73144451
142MP0002095_abnormal_skin_pigmentation0.73028735
143MP0005195_abnormal_posterior_eye0.72935099
144MP0000653_abnormal_sex_gland0.72806103
145MP0005409_darkened_coat_color0.72738687
146MP0003315_abnormal_perineum_morphology0.72519502
147MP0002837_dystrophic_cardiac_calcinosis0.71702651
148MP0002163_abnormal_gland_morphology0.71151280

Predicted human phenotypes

RankGene SetZ-score
1Medial flaring of the eyebrow (HP:0010747)4.94987468
2Absent/shortened dynein arms (HP:0200106)4.67798719
3Dynein arm defect of respiratory motile cilia (HP:0012255)4.67798719
4Gait imbalance (HP:0002141)4.65971362
5Congenital primary aphakia (HP:0007707)4.57753506
6Nephrogenic diabetes insipidus (HP:0009806)4.50465880
7Genital tract atresia (HP:0001827)3.57785520
8Vaginal atresia (HP:0000148)3.47959811
9Poor coordination (HP:0002370)3.47891941
10Pancreatic fibrosis (HP:0100732)3.23736602
11True hermaphroditism (HP:0010459)3.22523009
12Abnormal hair whorl (HP:0010721)3.05087707
13Parakeratosis (HP:0001036)3.03693055
14Papillary thyroid carcinoma (HP:0002895)3.03484581
15Hypoglycemic coma (HP:0001325)3.03080644
16Febrile seizures (HP:0002373)3.01630688
17Type 2 muscle fiber atrophy (HP:0003554)3.00574223
18Exercise-induced muscle cramps (HP:0003710)2.95098876
19Abnormal respiratory motile cilium morphology (HP:0005938)2.87957437
20Abnormal respiratory epithelium morphology (HP:0012253)2.87957437
21Absent eyebrow (HP:0002223)2.87272738
22Aplasia/Hypoplasia of the lens (HP:0008063)2.86503454
23Abnormal ciliary motility (HP:0012262)2.86249910
243-Methylglutaconic aciduria (HP:0003535)2.85408294
25Increased CSF lactate (HP:0002490)2.83600291
26Hepatic necrosis (HP:0002605)2.79853830
27Focal motor seizures (HP:0011153)2.76920352
28Atonic seizures (HP:0010819)2.73059843
29Broad foot (HP:0001769)2.71205872
30Abnormality of incisor morphology (HP:0011063)2.70026830
31Acute encephalopathy (HP:0006846)2.69981157
32Hypothermia (HP:0002045)2.65524630
33Specific learning disability (HP:0001328)2.60333904
34Abnormal respiratory motile cilium physiology (HP:0012261)2.59437107
35Renal cortical cysts (HP:0000803)2.57902545
36Upper limb muscle weakness (HP:0003484)2.52345523
37Hepatocellular necrosis (HP:0001404)2.52306825
38Hyperinsulinemic hypoglycemia (HP:0000825)2.52109445
39Acute necrotizing encephalopathy (HP:0006965)2.38271032
40Muscular hypotonia of the trunk (HP:0008936)2.37410504
41Epileptic encephalopathy (HP:0200134)2.34989623
42Pancreatic cysts (HP:0001737)2.34404519
43Congenital stationary night blindness (HP:0007642)2.34338253
44Muscle fiber atrophy (HP:0100295)2.33452658
45Abnormality of the metopic suture (HP:0005556)2.32212740
46Postaxial hand polydactyly (HP:0001162)2.29966668
47Nemaline bodies (HP:0003798)2.28327247
48Hypoglycemic seizures (HP:0002173)2.27017958
49Abnormal mitochondria in muscle tissue (HP:0008316)2.25762425
50Astigmatism (HP:0000483)2.25688746
51Prominent metopic ridge (HP:0005487)2.25666809
52Lactic acidosis (HP:0003128)2.23745911
53Increased hepatocellular lipid droplets (HP:0006565)2.23567427
54Fetal akinesia sequence (HP:0001989)2.21846186
55Volvulus (HP:0002580)2.19282201
56Muscle fiber inclusion bodies (HP:0100299)2.18863841
57Optic nerve hypoplasia (HP:0000609)2.17713961
58Neuroendocrine neoplasm (HP:0100634)2.16563674
59Autoamputation (HP:0001218)2.11632351
60Ketoacidosis (HP:0001993)2.11337110
61Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.10467869
62Drooling (HP:0002307)2.08056281
63Flat capital femoral epiphysis (HP:0003370)2.07741533
64Generalized aminoaciduria (HP:0002909)2.07727912
65Hypsarrhythmia (HP:0002521)2.07192398
66Poor suck (HP:0002033)2.07125138
67Methylmalonic acidemia (HP:0002912)2.06717470
68Aplasia/Hypoplasia of the tongue (HP:0010295)2.06573666
69Recurrent corneal erosions (HP:0000495)2.06405758
70Amyotrophic lateral sclerosis (HP:0007354)2.06313318
71Follicular hyperkeratosis (HP:0007502)2.06104219
72Rimmed vacuoles (HP:0003805)2.06012063
73Renal Fanconi syndrome (HP:0001994)2.05114722
74Pheochromocytoma (HP:0002666)2.04696993
75Thyroid-stimulating hormone excess (HP:0002925)2.04286871
76Increased serum lactate (HP:0002151)2.02185428
77Abnormality of dental color (HP:0011073)2.02094696
78Hypoplasia of the fovea (HP:0007750)2.01921416
79Aplasia/Hypoplasia of the fovea (HP:0008060)2.01921416
80Ependymoma (HP:0002888)2.00916790
81Cerebral edema (HP:0002181)2.00610143
82Abnormality of the labia minora (HP:0012880)2.00502803
83EEG with generalized epileptiform discharges (HP:0011198)1.99921157
84Lissencephaly (HP:0001339)1.98332449
85Patchy hypopigmentation of hair (HP:0011365)1.98044271
86Progressive macrocephaly (HP:0004481)1.96920819
87Short tibia (HP:0005736)1.96284913
88Exercise intolerance (HP:0003546)1.96256791
89Abnormality of the renal cortex (HP:0011035)1.95995570
90Abnormality of the astrocytes (HP:0100707)1.95544653
91Astrocytoma (HP:0009592)1.95544653
92Abnormality of the musculature of the pelvis (HP:0001469)1.95149154
93Abnormality of the hip-girdle musculature (HP:0001445)1.95149154
94Short foot (HP:0001773)1.95080189
95Abnormality of midbrain morphology (HP:0002418)1.92373005
96Molar tooth sign on MRI (HP:0002419)1.92373005
97Palpitations (HP:0001962)1.92102547
98Aplasia/Hypoplasia of the tibia (HP:0005772)1.92027008
99Lipid accumulation in hepatocytes (HP:0006561)1.91996808
100Median cleft lip (HP:0000161)1.91095983
101Aganglionic megacolon (HP:0002251)1.90733425
102White forelock (HP:0002211)1.90466696
103Aplasia/hypoplasia of the uterus (HP:0008684)1.89851757
104Atrophy/Degeneration involving motor neurons (HP:0007373)1.89775749
105Abnormality of the calf musculature (HP:0001430)1.89620239
106Epileptiform EEG discharges (HP:0011182)1.89284492
107Muscle hypertrophy of the lower extremities (HP:0008968)1.89046052
108Left ventricular hypertrophy (HP:0001712)1.88790080
109Postnatal microcephaly (HP:0005484)1.88084784
110Decreased testicular size (HP:0008734)1.87630937
111Renal dysplasia (HP:0000110)1.87197421
112Adrenal hypoplasia (HP:0000835)1.86860871
113Nonprogressive disorder (HP:0003680)1.86832974
114Excessive salivation (HP:0003781)1.85709886
115Progressive inability to walk (HP:0002505)1.85059059
116Absent eyelashes (HP:0000561)1.84584217
117Cutaneous melanoma (HP:0012056)1.83668668
118Abnormality of the fovea (HP:0000493)1.82841082
119Retinal dysplasia (HP:0007973)1.82829753
120Chromosomal breakage induced by crosslinking agents (HP:0003221)1.82662607
121Absent speech (HP:0001344)1.82626927
122Neoplasm of the adrenal gland (HP:0100631)1.82557286
123Abnormality of the pancreatic islet cells (HP:0006476)1.81359477
124Abnormality of endocrine pancreas physiology (HP:0012093)1.81359477
125Ankle clonus (HP:0011448)1.80970491
126Chromsome breakage (HP:0040012)1.80636481
127Failure to thrive in infancy (HP:0001531)1.79876640
128Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.79701718
129Septo-optic dysplasia (HP:0100842)1.79504283
130Hepatoblastoma (HP:0002884)1.79477377
131Abnormality of the intervertebral disk (HP:0005108)1.79168471
132Tongue fasciculations (HP:0001308)1.78767724
133Neoplasm of the peripheral nervous system (HP:0100007)1.78025534
134Polyphagia (HP:0002591)1.77791637
135Hyperventilation (HP:0002883)1.77642425
136Birth length less than 3rd percentile (HP:0003561)1.77322696
137Preaxial hand polydactyly (HP:0001177)1.77121746
138Postaxial foot polydactyly (HP:0001830)1.75975015
139Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.75181557
140Abnormality of alanine metabolism (HP:0010916)1.75181557
141Hyperalaninemia (HP:0003348)1.75181557
142Hypoplastic heart (HP:0001961)1.74875728
143Progressive cerebellar ataxia (HP:0002073)1.74865914
144Thyroid carcinoma (HP:0002890)1.74289452
145Congenital sensorineural hearing impairment (HP:0008527)1.73668081
146Increased intramyocellular lipid droplets (HP:0012240)1.73662068
147Delayed gross motor development (HP:0002194)1.71863224
148Abnormality of the femoral head (HP:0003368)1.70255153
149Nephronophthisis (HP:0000090)1.69590721
150Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.66786079
151Retinitis pigmentosa (HP:0000510)1.66034447
152Hypoplastic left heart (HP:0004383)1.65501986
153Irregular epiphyses (HP:0010582)1.65486618
154Abolished electroretinogram (ERG) (HP:0000550)1.65396818
155Multicystic kidney dysplasia (HP:0000003)1.64299728
156Abnormality of macular pigmentation (HP:0008002)1.62409594
157Severe visual impairment (HP:0001141)1.61740986
158Dental crowding (HP:0000678)1.59961491
159Hypoplastic iliac wings (HP:0002866)1.59234345
160Mitochondrial inheritance (HP:0001427)1.58192017
161Anterior segment dysgenesis (HP:0007700)1.56965436
162Absent septum pellucidum (HP:0001331)1.53745408
163Abnormality of the epiphysis of the femoral head (HP:0010574)1.53578413
164Gaze-evoked nystagmus (HP:0000640)1.52987190
165Limb dystonia (HP:0002451)1.52715186
166Chronic hepatic failure (HP:0100626)1.52208554
167Patellar aplasia (HP:0006443)1.50559662
168Hypergonadotropic hypogonadism (HP:0000815)1.49062858

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.83160693
2TRIM283.84669986
3SIK33.63592305
4MAP2K73.63506062
5BMPR23.02793605
6MAP3K122.79485480
7MUSK2.78351977
8CDK82.62450047
9MAP3K42.44491880
10FRK2.28549454
11PLK42.25347891
12EIF2AK12.12239943
13PLK22.10448267
14MAPK132.09028416
15MST42.07132842
16ERBB32.05386896
17STK38L2.00876546
18BMPR1B1.98011139
19AKT31.86980071
20SGK21.83572942
21CCNB11.76636412
22STK161.72535646
23MAP4K21.70934731
24TNIK1.66417900
25NEK11.57916756
26LIMK11.56595810
27CSNK1G21.53684904
28DYRK21.48930474
29SGK2231.47315865
30SGK4941.47315865
31TXK1.46917143
32ADRBK21.41345716
33MKNK21.39472687
34YES11.39159702
35CSNK1G11.38694140
36MAP3K61.38632471
37LATS11.37754963
38BRAF1.36367305
39MARK11.34158431
40BRD41.31183818
41EIF2AK31.26132083
42EPHA41.25180102
43PAK31.24581279
44PBK1.23956141
45NTRK31.20446064
46TESK11.20130240
47PRPF4B1.19646480
48MKNK11.18889160
49ACVR1B1.12336772
50PDK21.05169984
51NME11.04820898
52STK391.04329717
53MOS1.01491873
54TSSK61.01196563
55BCR1.00308093
56WEE10.99583423
57PLK30.99255794
58NEK60.96136131
59PINK10.96067142
60MAP3K50.95437793
61MYLK0.88971564
62CDK30.88970713
63LATS20.87459312
64MAPKAPK30.84614031
65MAP2K40.84325161
66SGK30.82620693
67DAPK10.81967451
68BRSK20.80885959
69MINK10.78341474
70RPS6KA40.75259137
71FER0.73653029
72SCYL20.71364136
73WNK30.69535865
74PNCK0.67231308
75GRK10.66414150
76CDK90.65628444
77VRK10.65560179
78CAMK2A0.64207987
79CHEK20.63655413
80DYRK1A0.63415209
81BCKDK0.63131545
82PRKD30.62206534
83TIE10.61383624
84ZAK0.61214262
85PRKCE0.60381760
86NTRK20.58857708
87RAF10.58547640
88PIK3CG0.58092932
89STK30.57538522
90ERBB40.55748687
91PAK60.54780598
92PRKCG0.54636462
93GRK70.51176272
94ADRBK10.50664238
95SRPK10.48867681
96PIK3CA0.48563921
97CAMK2D0.48460920
98BUB10.46974111
99OBSCN0.46964767
100EIF2AK20.46700390
101BRSK10.45749069
102INSRR0.45162592
103ROCK10.44521805
104KSR10.43997405
105TAOK30.43244076
106EPHA30.42239806
107PLK10.41257908
108NLK0.40962027
109CDK50.39882572
110DAPK20.39580296
111CDK190.39260708
112MAP2K60.38860112
113CAMKK20.38427640
114CAMK2G0.37750716
115CSNK1G30.36538042
116NUAK10.33841139
117STK240.33739909
118SIK20.32717534
119PRKG10.31939139
120SGK10.31495916
121PRKAA10.30777480
122CDK140.30497628
123CSNK1A1L0.30493238
124TTK0.30452207
125ARAF0.30366246
126PRKACA0.28744847
127PRKACB0.28227071
128RPS6KA50.26052355
129ABL10.25940196
130TAOK10.25598522
131MAPK70.24538366
132PDK40.24461950
133PDK30.24461950
134OXSR10.24192653
135CAMK2B0.24172939
136PHKG10.23388144
137PHKG20.23388144

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.80223162
2Synaptic vesicle cycle_Homo sapiens_hsa047212.68910616
3Basal transcription factors_Homo sapiens_hsa030222.29456011
4SNARE interactions in vesicular transport_Homo sapiens_hsa041302.26675196
5Sulfur metabolism_Homo sapiens_hsa009202.25989096
6Olfactory transduction_Homo sapiens_hsa047402.20525922
7Collecting duct acid secretion_Homo sapiens_hsa049662.16689003
8Propanoate metabolism_Homo sapiens_hsa006402.07353924
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.06132906
10Phototransduction_Homo sapiens_hsa047442.03022740
11Fatty acid elongation_Homo sapiens_hsa000622.02319777
12Circadian rhythm_Homo sapiens_hsa047101.89562136
13Morphine addiction_Homo sapiens_hsa050321.86215023
14Serotonergic synapse_Homo sapiens_hsa047261.77392558
15RNA polymerase_Homo sapiens_hsa030201.73591858
16Butanoate metabolism_Homo sapiens_hsa006501.72720870
17GABAergic synapse_Homo sapiens_hsa047271.70295869
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.66051124
19RNA degradation_Homo sapiens_hsa030181.64651668
20Vibrio cholerae infection_Homo sapiens_hsa051101.63362561
21Circadian entrainment_Homo sapiens_hsa047131.62013829
22Proteasome_Homo sapiens_hsa030501.61264071
23Selenocompound metabolism_Homo sapiens_hsa004501.59578493
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.53625577
25Taste transduction_Homo sapiens_hsa047421.47217767
26Glutamatergic synapse_Homo sapiens_hsa047241.42456627
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.40168824
28Protein export_Homo sapiens_hsa030601.39988698
29Cardiac muscle contraction_Homo sapiens_hsa042601.38799785
30Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.37799786
31Cell cycle_Homo sapiens_hsa041101.35514325
32Ovarian steroidogenesis_Homo sapiens_hsa049131.31954522
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.31413637
34Oxidative phosphorylation_Homo sapiens_hsa001901.30084423
35Dopaminergic synapse_Homo sapiens_hsa047281.29162667
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.26759914
37Rheumatoid arthritis_Homo sapiens_hsa053231.21035594
38Autoimmune thyroid disease_Homo sapiens_hsa053201.15300060
39Fanconi anemia pathway_Homo sapiens_hsa034601.15013506
40Steroid biosynthesis_Homo sapiens_hsa001001.14549180
41Regulation of autophagy_Homo sapiens_hsa041401.10124683
42Peroxisome_Homo sapiens_hsa041461.09829439
43Homologous recombination_Homo sapiens_hsa034401.09752707
44Insulin secretion_Homo sapiens_hsa049111.08506930
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.07320392
46Amphetamine addiction_Homo sapiens_hsa050311.06227318
47Pyruvate metabolism_Homo sapiens_hsa006201.05645347
48Cholinergic synapse_Homo sapiens_hsa047251.05642926
49Purine metabolism_Homo sapiens_hsa002301.05496022
50Oocyte meiosis_Homo sapiens_hsa041141.04155347
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02661265
52beta-Alanine metabolism_Homo sapiens_hsa004101.00567423
53Parkinsons disease_Homo sapiens_hsa050121.00309678
54Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99532390
55Calcium signaling pathway_Homo sapiens_hsa040200.99215973
56Axon guidance_Homo sapiens_hsa043600.97528470
57Sphingolipid metabolism_Homo sapiens_hsa006000.96047132
58Huntingtons disease_Homo sapiens_hsa050160.95219537
59Phagosome_Homo sapiens_hsa041450.93967619
60Long-term depression_Homo sapiens_hsa047300.93767839
61Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91637415
62Allograft rejection_Homo sapiens_hsa053300.88484095
63Cocaine addiction_Homo sapiens_hsa050300.87462638
642-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.86230259
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.82804685
66Type I diabetes mellitus_Homo sapiens_hsa049400.81616658
67Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.81025705
68Long-term potentiation_Homo sapiens_hsa047200.80182957
69mRNA surveillance pathway_Homo sapiens_hsa030150.79299024
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79133101
71Oxytocin signaling pathway_Homo sapiens_hsa049210.78051821
72Ether lipid metabolism_Homo sapiens_hsa005650.77138845
73Maturity onset diabetes of the young_Homo sapiens_hsa049500.76523100
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74504435
75Colorectal cancer_Homo sapiens_hsa052100.74229752
76Folate biosynthesis_Homo sapiens_hsa007900.73941980
77Fatty acid metabolism_Homo sapiens_hsa012120.70539116
78Renin secretion_Homo sapiens_hsa049240.69333125
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68754278
80Ras signaling pathway_Homo sapiens_hsa040140.68586899
81RNA transport_Homo sapiens_hsa030130.68317691
82Asthma_Homo sapiens_hsa053100.67719444
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.67272210
84Non-homologous end-joining_Homo sapiens_hsa034500.66926220
85Spliceosome_Homo sapiens_hsa030400.66564625
86Alzheimers disease_Homo sapiens_hsa050100.65882762
87cAMP signaling pathway_Homo sapiens_hsa040240.65434389
88Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.65128252
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.64775127
90Melanoma_Homo sapiens_hsa052180.61339879
91Metabolic pathways_Homo sapiens_hsa011000.59743309
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.58588611
93Aldosterone synthesis and secretion_Homo sapiens_hsa049250.57339405
94Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57111565
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.56419626
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56334017
97Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.56214343
98Wnt signaling pathway_Homo sapiens_hsa043100.55892688
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54630835
100Alcoholism_Homo sapiens_hsa050340.52339371
101Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52217975
102MAPK signaling pathway_Homo sapiens_hsa040100.51664469
103Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.51511297
104Base excision repair_Homo sapiens_hsa034100.51133811
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.50257815
106Shigellosis_Homo sapiens_hsa051310.49186843
107Mismatch repair_Homo sapiens_hsa034300.49054030
108Carbon metabolism_Homo sapiens_hsa012000.48211558
109Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.48035010
110Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47421566
111Pyrimidine metabolism_Homo sapiens_hsa002400.46921370
112ErbB signaling pathway_Homo sapiens_hsa040120.46803573
113Gap junction_Homo sapiens_hsa045400.46532069
114GnRH signaling pathway_Homo sapiens_hsa049120.45901213
115Type II diabetes mellitus_Homo sapiens_hsa049300.45836369
116Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44319045
117Prolactin signaling pathway_Homo sapiens_hsa049170.43729948
118Nucleotide excision repair_Homo sapiens_hsa034200.43018414
119Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.43007843
120Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.42238329
121Dilated cardiomyopathy_Homo sapiens_hsa054140.42148553
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.41558154
123Vitamin B6 metabolism_Homo sapiens_hsa007500.40983350
124Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.40801175
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.40789447
126Caffeine metabolism_Homo sapiens_hsa002320.40660590
127Glutathione metabolism_Homo sapiens_hsa004800.40546441
128TGF-beta signaling pathway_Homo sapiens_hsa043500.40384286
129Salivary secretion_Homo sapiens_hsa049700.40073045
130Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39809032
131Pancreatic cancer_Homo sapiens_hsa052120.39712691
132Hippo signaling pathway_Homo sapiens_hsa043900.39413337
133Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38397876
134Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.37273533
135Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34538571
136p53 signaling pathway_Homo sapiens_hsa041150.34483466
137Fatty acid biosynthesis_Homo sapiens_hsa000610.26437485
138Salmonella infection_Homo sapiens_hsa051320.26063841
139Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.22424732
140Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20527418

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