Rank | Gene Set | Z-score |
---|---|---|
1 | sarcomere organization (GO:0045214) | 8.49057944 |
2 | cardiac myofibril assembly (GO:0055003) | 8.13972265 |
3 | actin-myosin filament sliding (GO:0033275) | 8.11509742 |
4 | muscle filament sliding (GO:0030049) | 8.11509742 |
5 | myofibril assembly (GO:0030239) | 7.61225218 |
6 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 7.48405597 |
7 | actin-mediated cell contraction (GO:0070252) | 6.81994260 |
8 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 6.75001376 |
9 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 6.49527789 |
10 | cardiac muscle contraction (GO:0060048) | 6.45084746 |
11 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 6.32131786 |
12 | regulation of skeletal muscle contraction (GO:0014819) | 6.13130283 |
13 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 6.12781727 |
14 | cardiac muscle cell development (GO:0055013) | 6.02464632 |
15 | cardiac cell development (GO:0055006) | 5.67549328 |
16 | cardiac muscle hypertrophy (GO:0003300) | 5.65027682 |
17 | actomyosin structure organization (GO:0031032) | 5.63974190 |
18 | striated muscle contraction (GO:0006941) | 5.62820732 |
19 | regulation of sarcomere organization (GO:0060297) | 5.58692886 |
20 | response to muscle activity (GO:0014850) | 5.58118032 |
21 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 5.57202853 |
22 | regulation of actin filament-based movement (GO:1903115) | 5.53637610 |
23 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 5.53279452 |
24 | plasma membrane repair (GO:0001778) | 5.51239817 |
25 | regulation of relaxation of muscle (GO:1901077) | 5.47508346 |
26 | cardiac muscle tissue morphogenesis (GO:0055008) | 5.44829776 |
27 | striated muscle hypertrophy (GO:0014897) | 5.39997262 |
28 | tricarboxylic acid cycle (GO:0006099) | 5.33563739 |
29 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 5.22417950 |
30 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 5.18714447 |
31 | adult heart development (GO:0007512) | 5.17831289 |
32 | regulation of cell communication by electrical coupling (GO:0010649) | 5.11050016 |
33 | actin filament-based movement (GO:0030048) | 5.10239712 |
34 | ventricular cardiac muscle cell action potential (GO:0086005) | 5.05177011 |
35 | heart trabecula formation (GO:0060347) | 5.02255417 |
36 | muscle tissue morphogenesis (GO:0060415) | 5.00380187 |
37 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 5.00312988 |
38 | creatine metabolic process (GO:0006600) | 4.95878628 |
39 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 4.83393329 |
40 | regulation of striated muscle contraction (GO:0006942) | 4.76639192 |
41 | muscle hypertrophy (GO:0014896) | 4.71759946 |
42 | heart process (GO:0003015) | 4.70376253 |
43 | heart contraction (GO:0060047) | 4.70376253 |
44 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 4.69280278 |
45 | skeletal muscle fiber development (GO:0048741) | 4.68307632 |
46 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 4.61309952 |
47 | regulation of membrane repolarization (GO:0060306) | 4.61052746 |
48 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.58867116 |
49 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.57619716 |
50 | carnitine shuttle (GO:0006853) | 4.54448829 |
51 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.44726533 |
52 | myotube cell development (GO:0014904) | 4.44573627 |
53 | skeletal muscle contraction (GO:0003009) | 4.43271690 |
54 | regulation of the force of heart contraction (GO:0002026) | 4.37457336 |
55 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 4.28669282 |
56 | muscle hypertrophy in response to stress (GO:0003299) | 4.28669282 |
57 | cardiac muscle adaptation (GO:0014887) | 4.28669282 |
58 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.24398123 |
59 | skeletal muscle adaptation (GO:0043501) | 4.21925571 |
60 | regulation of cofactor metabolic process (GO:0051193) | 4.21269486 |
61 | regulation of coenzyme metabolic process (GO:0051196) | 4.21269486 |
62 | cell communication involved in cardiac conduction (GO:0086065) | 4.19902058 |
63 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.13795299 |
64 | ATP synthesis coupled proton transport (GO:0015986) | 4.13795299 |
65 | response to inactivity (GO:0014854) | 4.06825515 |
66 | cell communication by electrical coupling (GO:0010644) | 4.00191126 |
67 | NADH metabolic process (GO:0006734) | 3.98665502 |
68 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 3.97757477 |
69 | skeletal muscle tissue development (GO:0007519) | 3.97259091 |
70 | muscle cell fate commitment (GO:0042693) | 3.91923718 |
71 | negative regulation of protein localization to cell surface (GO:2000009) | 3.91521247 |
72 | striated muscle cell development (GO:0055002) | 3.89116418 |
73 | muscle contraction (GO:0006936) | 3.82938787 |
74 | cardiac muscle cell action potential (GO:0086001) | 3.82324259 |
75 | fatty acid transmembrane transport (GO:1902001) | 3.81100952 |
76 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.80571334 |
77 | regulation of cardiac muscle contraction (GO:0055117) | 3.79711571 |
78 | regulation of heart rate (GO:0002027) | 3.78279164 |
79 | striated muscle adaptation (GO:0014888) | 3.78103158 |
80 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.76051788 |
81 | negative regulation of potassium ion transport (GO:0043267) | 3.70274536 |
82 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.70008908 |
83 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.67685728 |
84 | respiratory electron transport chain (GO:0022904) | 3.64111724 |
85 | glycogen catabolic process (GO:0005980) | 3.62638952 |
86 | regulation of cardioblast differentiation (GO:0051890) | 3.60084336 |
87 | ventricular cardiac muscle cell development (GO:0055015) | 3.59965318 |
88 | muscle system process (GO:0003012) | 3.57652467 |
89 | cardiac conduction (GO:0061337) | 3.55610578 |
90 | electron transport chain (GO:0022900) | 3.54046868 |
91 | muscle organ development (GO:0007517) | 3.53655011 |
92 | muscle structure development (GO:0061061) | 3.53619531 |
93 | cardiac chamber formation (GO:0003207) | 3.52852726 |
94 | relaxation of cardiac muscle (GO:0055119) | 3.52470507 |
95 | glycogen biosynthetic process (GO:0005978) | 3.52067200 |
96 | glucan biosynthetic process (GO:0009250) | 3.52067200 |
97 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.46561231 |
98 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.46561231 |
99 | striated muscle atrophy (GO:0014891) | 3.44707629 |
100 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.43744159 |
101 | regulation of heart contraction (GO:0008016) | 3.43520143 |
102 | regulation of muscle system process (GO:0090257) | 3.43070175 |
103 | regulation of ATPase activity (GO:0043462) | 3.40068184 |
104 | regulation of ATP catabolic process (GO:1903289) | 3.40068184 |
105 | regulation of sulfur metabolic process (GO:0042762) | 3.39612393 |
106 | oxidative phosphorylation (GO:0006119) | 3.39375099 |
107 | regulation of heart rate by cardiac conduction (GO:0086091) | 3.37902293 |
108 | muscle adaptation (GO:0043500) | 3.37618772 |
109 | glucan catabolic process (GO:0009251) | 3.37241522 |
110 | regulation of muscle contraction (GO:0006937) | 3.36507951 |
111 | positive regulation of myotube differentiation (GO:0010831) | 3.36279230 |
112 | muscle cell development (GO:0055001) | 3.36125263 |
113 | muscle fiber development (GO:0048747) | 3.35941966 |
114 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.35632825 |
115 | regulation of striated muscle cell apoptotic process (GO:0010662) | 3.31893950 |
116 | muscle cell cellular homeostasis (GO:0046716) | 3.31773704 |
117 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.27148716 |
118 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.27148716 |
119 | positive regulation of cation channel activity (GO:2001259) | 3.26807420 |
120 | carnitine transmembrane transport (GO:1902603) | 3.26533122 |
121 | relaxation of muscle (GO:0090075) | 3.25858855 |
122 | trabecula formation (GO:0060343) | 3.25624781 |
123 | regulation of myoblast differentiation (GO:0045661) | 3.23610310 |
124 | positive regulation of myoblast differentiation (GO:0045663) | 3.19170799 |
125 | skeletal muscle tissue regeneration (GO:0043403) | 3.17989447 |
126 | striated muscle tissue development (GO:0014706) | 3.17652194 |
127 | cellular polysaccharide catabolic process (GO:0044247) | 3.13591994 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 4.48577431 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.19486509 |
3 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 3.62730422 |
4 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.49396467 |
5 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 3.06987516 |
6 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 3.06987516 |
7 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 3.05041336 |
8 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.90973672 |
9 | * MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 2.70699650 |
10 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.48026820 |
11 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.39558874 |
12 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.24090924 |
13 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.18063397 |
14 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.08687960 |
15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.03046294 |
16 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.99414350 |
17 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.99414350 |
18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.96748419 |
19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.89462965 |
20 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.85169104 |
21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.83619872 |
22 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.81282331 |
23 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.81001970 |
24 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.78328712 |
25 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.76857573 |
26 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.68200457 |
27 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.62832421 |
28 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.62206269 |
29 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.60596468 |
30 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.59065594 |
31 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.54425293 |
32 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.54101825 |
33 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.47628076 |
34 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.47439486 |
35 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.46915551 |
36 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.43814385 |
37 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.43221010 |
38 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.39750696 |
39 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.39462868 |
40 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.36185370 |
41 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.35356220 |
42 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.34029148 |
43 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.29906356 |
44 | VDR_22108803_ChIP-Seq_LS180_Human | 1.28605408 |
45 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.27815895 |
46 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.25765703 |
47 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.24293449 |
48 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.22708050 |
49 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.22342904 |
50 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.21433908 |
51 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.21378188 |
52 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21222030 |
53 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.18708506 |
54 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.18327390 |
55 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.16559544 |
56 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.14276518 |
57 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.12817144 |
58 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.10959726 |
59 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.09919491 |
60 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.09649856 |
61 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.08986944 |
62 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.08076692 |
63 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.08040907 |
64 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.07427413 |
65 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.07302949 |
66 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.04971060 |
67 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.03889325 |
68 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.02918439 |
69 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.02737598 |
70 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.01680889 |
71 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.00830703 |
72 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.00733244 |
73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.00584414 |
74 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.00451773 |
75 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.99598629 |
76 | AR_19668381_ChIP-Seq_PC3_Human | 0.99489248 |
77 | TP53_16413492_ChIP-PET_HCT116_Human | 0.99423911 |
78 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.99334836 |
79 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.99282056 |
80 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.99019332 |
81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.98891628 |
82 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.95822197 |
83 | * WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.95158831 |
84 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.94915929 |
85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94871580 |
86 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.94662854 |
87 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.94360225 |
88 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94335405 |
89 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.94305310 |
90 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.94197815 |
91 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94148352 |
92 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.93956662 |
93 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.93454875 |
94 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.93293153 |
95 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.92135554 |
96 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.90923606 |
97 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90871254 |
98 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.90649470 |
99 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.90469271 |
100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.90151233 |
101 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.90045893 |
102 | CJUN_26792858_Chip-Seq_BT549_Human | 0.89986227 |
103 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.89927355 |
104 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.89147022 |
105 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.88540043 |
106 | GATA1_22025678_ChIP-Seq_K562_Human | 0.88372960 |
107 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.88307244 |
108 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.87435494 |
109 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.87384183 |
110 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.86975710 |
111 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.86307127 |
112 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.86170027 |
113 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.85915977 |
114 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.85915828 |
115 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.85523412 |
116 | PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 0.84469946 |
117 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.83224150 |
118 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.80533961 |
119 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.80533961 |
120 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.80314317 |
121 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.79661208 |
122 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.79390655 |
123 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.79233999 |
124 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.77038063 |
125 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.75589966 |
126 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.75527014 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 5.87851161 |
2 | MP0004084_abnormal_cardiac_muscle | 5.42979440 |
3 | MP0000751_myopathy | 5.09877608 |
4 | MP0003646_muscle_fatigue | 4.78358183 |
5 | MP0000749_muscle_degeneration | 4.62825103 |
6 | MP0004036_abnormal_muscle_relaxation | 4.42164979 |
7 | MP0004215_abnormal_myocardial_fiber | 4.39088178 |
8 | MP0005330_cardiomyopathy | 3.75813407 |
9 | MP0004145_abnormal_muscle_electrophysio | 3.67516119 |
10 | MP0004087_abnormal_muscle_fiber | 3.21515701 |
11 | MP0002972_abnormal_cardiac_muscle | 3.11393950 |
12 | MP0005620_abnormal_muscle_contractility | 3.00130943 |
13 | MP0003137_abnormal_impulse_conducting | 2.89277927 |
14 | MP0002106_abnormal_muscle_physiology | 2.88669830 |
15 | MP0000750_abnormal_muscle_regeneration | 2.71951734 |
16 | MP0008775_abnormal_heart_ventricle | 2.63956199 |
17 | MP0010630_abnormal_cardiac_muscle | 2.48478499 |
18 | MP0002269_muscular_atrophy | 2.43684194 |
19 | MP0004484_altered_response_of | 2.42986472 |
20 | MP0005385_cardiovascular_system_phenoty | 2.39777664 |
21 | MP0001544_abnormal_cardiovascular_syste | 2.39777664 |
22 | MP0005369_muscle_phenotype | 2.38629131 |
23 | MP0000747_muscle_weakness | 2.36261769 |
24 | MP0000759_abnormal_skeletal_muscle | 2.28016863 |
25 | MP0006138_congestive_heart_failure | 2.27446926 |
26 | MP0004130_abnormal_muscle_cell | 2.25203896 |
27 | MP0004085_abnormal_heartbeat | 2.24161227 |
28 | MP0003828_pulmonary_edema | 2.02583438 |
29 | MP0004233_abnormal_muscle_weight | 2.00417140 |
30 | MP0002127_abnormal_cardiovascular_syste | 1.85412568 |
31 | MP0004510_myositis | 1.81915186 |
32 | MP0003221_abnormal_cardiomyocyte_apopto | 1.81702727 |
33 | MP0003950_abnormal_plasma_membrane | 1.62110258 |
34 | MP0003567_abnormal_fetal_cardiomyocyte | 1.43345403 |
35 | MP0006036_abnormal_mitochondrial_physio | 1.41840510 |
36 | MP0002234_abnormal_pharynx_morphology | 1.34778714 |
37 | MP0002332_abnormal_exercise_endurance | 1.34138231 |
38 | MP0002108_abnormal_muscle_morphology | 1.16240135 |
39 | MP0000733_abnormal_muscle_development | 1.15293384 |
40 | MP0000266_abnormal_heart_morphology | 1.12133149 |
41 | MP0001661_extended_life_span | 1.11326471 |
42 | MP0005623_abnormal_meninges_morphology | 0.98915985 |
43 | MP0006035_abnormal_mitochondrial_morpho | 0.93680086 |
44 | MP0010368_abnormal_lymphatic_system | 0.88174536 |
45 | MP0003122_maternal_imprinting | 0.86816178 |
46 | MP0003279_aneurysm | 0.80534728 |
47 | MP0005666_abnormal_adipose_tissue | 0.80013583 |
48 | MP0005165_increased_susceptibility_to | 0.78068374 |
49 | MP0004270_analgesia | 0.71837825 |
50 | MP0009384_cardiac_valve_regurgitation | 0.71592149 |
51 | MP0000230_abnormal_systemic_arterial | 0.71406665 |
52 | MP0010030_abnormal_orbit_morphology | 0.71384437 |
53 | MP0002128_abnormal_blood_circulation | 0.70847038 |
54 | MP0008438_abnormal_cutaneous_collagen | 0.70767719 |
55 | MP0000343_altered_response_to | 0.67383283 |
56 | MP0004272_abnormal_basement_membrane | 0.66940722 |
57 | MP0000013_abnormal_adipose_tissue | 0.66604561 |
58 | MP0005187_abnormal_penis_morphology | 0.63179962 |
59 | MP0005266_abnormal_metabolism | 0.62534141 |
60 | MP0009250_abnormal_appendicular_skeleto | 0.60393479 |
61 | MP0005375_adipose_tissue_phenotype | 0.57529819 |
62 | MP0003045_fibrosis | 0.57501986 |
63 | MP0005451_abnormal_body_composition | 0.55705832 |
64 | MP0001879_abnormal_lymphatic_vessel | 0.55605150 |
65 | MP0002909_abnormal_adrenal_gland | 0.55104213 |
66 | MP0003705_abnormal_hypodermis_morpholog | 0.52450175 |
67 | MP0002925_abnormal_cardiovascular_devel | 0.51538058 |
68 | MP0004859_abnormal_synaptic_plasticity | 0.51517001 |
69 | MP0002971_abnormal_brown_adipose | 0.51358706 |
70 | MP0004185_abnormal_adipocyte_glucose | 0.50879777 |
71 | MP0005275_abnormal_skin_tensile | 0.50658047 |
72 | MP0005377_hearing/vestibular/ear_phenot | 0.50130449 |
73 | MP0003878_abnormal_ear_physiology | 0.50130449 |
74 | MP0004134_abnormal_chest_morphology | 0.48809111 |
75 | MP0000767_abnormal_smooth_muscle | 0.47637791 |
76 | MP0009780_abnormal_chondrocyte_physiolo | 0.45759297 |
77 | MP0000534_abnormal_ureter_morphology | 0.45526528 |
78 | MP0002822_catalepsy | 0.44349120 |
79 | MP0005670_abnormal_white_adipose | 0.43503796 |
80 | MP0003385_abnormal_body_wall | 0.43338731 |
81 | MP0003123_paternal_imprinting | 0.43303790 |
82 | MP0001784_abnormal_fluid_regulation | 0.42954040 |
83 | MP0001485_abnormal_pinna_reflex | 0.42549389 |
84 | MP0000003_abnormal_adipose_tissue | 0.42398957 |
85 | MP0003880_abnormal_central_pattern | 0.42350420 |
86 | MP0003948_abnormal_gas_homeostasis | 0.42080639 |
87 | MP0002638_abnormal_pupillary_reflex | 0.41585193 |
88 | MP0008961_abnormal_basal_metabolism | 0.41278585 |
89 | MP0005386_behavior/neurological_phenoty | 0.41165380 |
90 | MP0004924_abnormal_behavior | 0.41165380 |
91 | MP0003566_abnormal_cell_adhesion | 0.41116771 |
92 | MP0003941_abnormal_skin_development | 0.39169551 |
93 | MP0002114_abnormal_axial_skeleton | 0.39095735 |
94 | MP0005423_abnormal_somatic_nervous | 0.38740751 |
95 | MP0003121_genomic_imprinting | 0.38261139 |
96 | MP0005503_abnormal_tendon_morphology | 0.38195467 |
97 | MP0002896_abnormal_bone_mineralization | 0.37342807 |
98 | MP0004043_abnormal_pH_regulation | 0.35790167 |
99 | MP0001299_abnormal_eye_distance/ | 0.34511231 |
100 | MP0001529_abnormal_vocalization | 0.34471210 |
101 | MP0003984_embryonic_growth_retardation | 0.33788875 |
102 | MP0002088_abnormal_embryonic_growth/wei | 0.33737635 |
103 | MP0000372_irregular_coat_pigmentation | 0.32596980 |
104 | MP0003635_abnormal_synaptic_transmissio | 0.32443565 |
105 | MP0001614_abnormal_blood_vessel | 0.31619114 |
106 | MP0005409_darkened_coat_color | 0.31176765 |
107 | MP0000762_abnormal_tongue_morphology | 0.30569250 |
108 | MP0002734_abnormal_mechanical_nocicepti | 0.30350980 |
109 | MP0002078_abnormal_glucose_homeostasis | 0.29432831 |
110 | MP0008569_lethality_at_weaning | 0.29381152 |
111 | MP0009745_abnormal_behavioral_response | 0.28757721 |
112 | MP0001440_abnormal_grooming_behavior | 0.27973053 |
113 | MP0005595_abnormal_vascular_smooth | 0.27954857 |
114 | MP0002249_abnormal_larynx_morphology | 0.27594988 |
115 | MP0002067_abnormal_sensory_capabilities | 0.26115733 |
116 | MP0005535_abnormal_body_temperature | 0.25361893 |
117 | MP0001943_abnormal_respiration | 0.24269556 |
118 | MP0006276_abnormal_autonomic_nervous | 0.23964007 |
119 | MP0001984_abnormal_olfaction | 0.23852875 |
120 | MP0004147_increased_porphyrin_level | 0.22489531 |
121 | MP0001958_emphysema | 0.20666273 |
122 | MP0004142_abnormal_muscle_tone | 0.20480147 |
123 | MP0003755_abnormal_palate_morphology | 0.20033809 |
124 | MP0009672_abnormal_birth_weight | 0.19943086 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 7.66480921 |
2 | Calf muscle hypertrophy (HP:0008981) | 6.85296369 |
3 | Exercise-induced myalgia (HP:0003738) | 6.54169078 |
4 | Muscle hypertrophy of the lower extremities (HP:0008968) | 6.52350712 |
5 | Exercise-induced muscle cramps (HP:0003710) | 6.44469606 |
6 | Abnormality of the calf musculature (HP:0001430) | 5.70393559 |
7 | Ventricular tachycardia (HP:0004756) | 5.69946823 |
8 | Muscle fiber splitting (HP:0003555) | 5.60654183 |
9 | Abnormality of the left ventricular outflow tract (HP:0011103) | 5.43665504 |
10 | Subaortic stenosis (HP:0001682) | 5.43665504 |
11 | Atrial fibrillation (HP:0005110) | 5.38154975 |
12 | Primary atrial arrhythmia (HP:0001692) | 5.06276157 |
13 | Supraventricular tachycardia (HP:0004755) | 4.87840530 |
14 | Hyporeflexia of lower limbs (HP:0002600) | 4.87729361 |
15 | Supraventricular arrhythmia (HP:0005115) | 4.77887862 |
16 | Lipoatrophy (HP:0100578) | 4.70452794 |
17 | Myoglobinuria (HP:0002913) | 4.62408088 |
18 | EMG: myopathic abnormalities (HP:0003458) | 4.54496024 |
19 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 4.51607397 |
20 | Muscle fiber inclusion bodies (HP:0100299) | 4.51545385 |
21 | Syncope (HP:0001279) | 4.48253105 |
22 | Type 1 muscle fiber predominance (HP:0003803) | 4.31105100 |
23 | Right ventricular cardiomyopathy (HP:0011663) | 4.24618766 |
24 | Prolonged QT interval (HP:0001657) | 4.18598928 |
25 | Dilated cardiomyopathy (HP:0001644) | 3.92634589 |
26 | Ventricular arrhythmia (HP:0004308) | 3.87690299 |
27 | Nemaline bodies (HP:0003798) | 3.86000022 |
28 | Calcaneovalgus deformity (HP:0001848) | 3.81166871 |
29 | Palpitations (HP:0001962) | 3.80527865 |
30 | Difficulty running (HP:0009046) | 3.75776762 |
31 | Bundle branch block (HP:0011710) | 3.72344645 |
32 | Asymmetric septal hypertrophy (HP:0001670) | 3.70957790 |
33 | Increased connective tissue (HP:0009025) | 3.62623169 |
34 | Rhabdomyolysis (HP:0003201) | 3.57303250 |
35 | Myotonia (HP:0002486) | 3.46723576 |
36 | Absent phalangeal crease (HP:0006109) | 3.45131493 |
37 | Deformed tarsal bones (HP:0008119) | 3.36065698 |
38 | Ventricular fibrillation (HP:0001663) | 3.26754860 |
39 | Heart block (HP:0012722) | 3.19565571 |
40 | Atrioventricular block (HP:0001678) | 3.06441045 |
41 | Abnormal EKG (HP:0003115) | 3.04333426 |
42 | Abnormal atrioventricular conduction (HP:0005150) | 3.00792339 |
43 | Left ventricular hypertrophy (HP:0001712) | 2.98565578 |
44 | Difficulty climbing stairs (HP:0003551) | 2.94504330 |
45 | Distal arthrogryposis (HP:0005684) | 2.91819524 |
46 | Neck muscle weakness (HP:0000467) | 2.91315741 |
47 | Frequent falls (HP:0002359) | 2.86525170 |
48 | Abnormal finger flexion creases (HP:0006143) | 2.83650390 |
49 | Muscle stiffness (HP:0003552) | 2.81519933 |
50 | Acute necrotizing encephalopathy (HP:0006965) | 2.76146868 |
51 | Round ear (HP:0100830) | 2.75863130 |
52 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.73731203 |
53 | Rimmed vacuoles (HP:0003805) | 2.67867762 |
54 | Increased variability in muscle fiber diameter (HP:0003557) | 2.63228850 |
55 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.58004408 |
56 | Distal lower limb muscle weakness (HP:0009053) | 2.55644947 |
57 | Popliteal pterygium (HP:0009756) | 2.55495670 |
58 | Abnormality of the neuromuscular junction (HP:0003398) | 2.52957840 |
59 | Fatigable weakness (HP:0003473) | 2.52957840 |
60 | Bulbar palsy (HP:0001283) | 2.50185640 |
61 | Weak cry (HP:0001612) | 2.47251164 |
62 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.41936699 |
63 | Areflexia of lower limbs (HP:0002522) | 2.35652529 |
64 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.32305232 |
65 | Progressive macrocephaly (HP:0004481) | 2.31730999 |
66 | Myopathic facies (HP:0002058) | 2.30686599 |
67 | Generalized muscle weakness (HP:0003324) | 2.27890415 |
68 | EMG: neuropathic changes (HP:0003445) | 2.26632845 |
69 | Gowers sign (HP:0003391) | 2.26199658 |
70 | Palmoplantar keratoderma (HP:0000982) | 2.24761210 |
71 | Congenital malformation of the right heart (HP:0011723) | 2.24260175 |
72 | Double outlet right ventricle (HP:0001719) | 2.24260175 |
73 | Abnormality of the calcaneus (HP:0008364) | 2.20235947 |
74 | Acute encephalopathy (HP:0006846) | 2.19980124 |
75 | Scapular winging (HP:0003691) | 2.18718730 |
76 | Hepatic necrosis (HP:0002605) | 2.16235521 |
77 | Exercise intolerance (HP:0003546) | 2.15360128 |
78 | Ragged-red muscle fibers (HP:0003200) | 2.15137863 |
79 | Limb-girdle muscle atrophy (HP:0003797) | 2.14424204 |
80 | Mitochondrial inheritance (HP:0001427) | 2.12011564 |
81 | Hypoplastic ischia (HP:0003175) | 2.11614904 |
82 | Abnormality of the foot musculature (HP:0001436) | 2.09598201 |
83 | Spinal rigidity (HP:0003306) | 2.05252314 |
84 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.03260689 |
85 | Distal lower limb amyotrophy (HP:0008944) | 2.02899008 |
86 | Slender build (HP:0001533) | 2.02644220 |
87 | Progressive muscle weakness (HP:0003323) | 2.02138558 |
88 | Waddling gait (HP:0002515) | 2.02114030 |
89 | Muscular dystrophy (HP:0003560) | 2.01973422 |
90 | Ulnar deviation of the wrist (HP:0003049) | 2.01059804 |
91 | Increased CSF lactate (HP:0002490) | 2.00462701 |
92 | Ketoacidosis (HP:0001993) | 1.99906255 |
93 | Hyperkalemia (HP:0002153) | 1.99693639 |
94 | Conjunctival hamartoma (HP:0100780) | 1.99044683 |
95 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.98239947 |
96 | Aplasia of the musculature (HP:0100854) | 1.97975614 |
97 | Type 2 muscle fiber atrophy (HP:0003554) | 1.96488285 |
98 | Hypoplastic heart (HP:0001961) | 1.94694333 |
99 | Hepatocellular necrosis (HP:0001404) | 1.94612731 |
100 | Respiratory insufficiency due to muscle weakness (HP:0002747) | 1.91193102 |
101 | Limited hip movement (HP:0008800) | 1.90323062 |
102 | Pheochromocytoma (HP:0002666) | 1.90288686 |
103 | Proximal amyotrophy (HP:0007126) | 1.90015447 |
104 | Foot dorsiflexor weakness (HP:0009027) | 1.89523962 |
105 | Nuclear cataract (HP:0100018) | 1.85690331 |
106 | Hip contracture (HP:0003273) | 1.85355240 |
107 | Testicular atrophy (HP:0000029) | 1.85100931 |
108 | Sudden cardiac death (HP:0001645) | 1.84073511 |
109 | Abnormality of the ischium (HP:0003174) | 1.81336836 |
110 | Cerebral edema (HP:0002181) | 1.80161583 |
111 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.78933346 |
112 | Abnormality of alanine metabolism (HP:0010916) | 1.78933346 |
113 | Hyperalaninemia (HP:0003348) | 1.78933346 |
114 | Malignant hyperthermia (HP:0002047) | 1.78510235 |
115 | Limb-girdle muscle weakness (HP:0003325) | 1.77816721 |
116 | Hypoplastic left heart (HP:0004383) | 1.77213469 |
117 | Increased muscle lipid content (HP:0009058) | 1.76189650 |
118 | Muscle fiber atrophy (HP:0100295) | 1.75436623 |
119 | Congestive heart failure (HP:0001635) | 1.75108429 |
120 | Fetal akinesia sequence (HP:0001989) | 1.73542411 |
121 | Facial diplegia (HP:0001349) | 1.73391187 |
122 | Lower limb amyotrophy (HP:0007210) | 1.68742299 |
123 | Steppage gait (HP:0003376) | 1.67064167 |
124 | Abnormality of placental membranes (HP:0011409) | 1.66998962 |
125 | Amniotic constriction ring (HP:0009775) | 1.66998962 |
126 | Metatarsus adductus (HP:0001840) | 1.65797062 |
127 | Long clavicles (HP:0000890) | 1.62274854 |
128 | Ulnar deviation of finger (HP:0009465) | 1.50774692 |
129 | Nonprogressive disorder (HP:0003680) | 1.49997982 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 6.65612091 |
2 | TTN | 4.94491590 |
3 | PHKG1 | 3.88966597 |
4 | PHKG2 | 3.88966597 |
5 | MYLK | 3.83110018 |
6 | DMPK | 3.41313244 |
7 | LMTK2 | 2.88270458 |
8 | PDK3 | 2.81432840 |
9 | PDK4 | 2.81432840 |
10 | PKN2 | 2.75895188 |
11 | STK24 | 2.70296722 |
12 | NEK1 | 2.43022035 |
13 | MUSK | 2.39670187 |
14 | PIK3CA | 2.19683872 |
15 | TRIB3 | 2.10326812 |
16 | ZAK | 1.82792670 |
17 | PDK2 | 1.55761527 |
18 | PINK1 | 1.55048788 |
19 | MARK1 | 1.52015598 |
20 | TIE1 | 1.44748298 |
21 | ILK | 1.44247412 |
22 | NME1 | 1.40273250 |
23 | PAK3 | 1.31512641 |
24 | CDC42BPA | 1.31261135 |
25 | STK38L | 1.29706242 |
26 | BCKDK | 1.26471002 |
27 | CAMK2D | 1.25595395 |
28 | GRK7 | 1.18602627 |
29 | MAP3K7 | 1.18200698 |
30 | MAPK12 | 1.11365206 |
31 | PIK3CG | 1.08679065 |
32 | ROCK1 | 1.07964865 |
33 | TRPM7 | 1.04064681 |
34 | PTK2B | 0.99206317 |
35 | PRKD1 | 0.96938316 |
36 | ERBB3 | 0.95318110 |
37 | CCNB1 | 0.94712892 |
38 | INSRR | 0.92285062 |
39 | EPHA4 | 0.88748349 |
40 | WNK4 | 0.87569341 |
41 | CAMK2A | 0.87481611 |
42 | DAPK3 | 0.83124198 |
43 | PRKAA1 | 0.74208812 |
44 | MAP2K4 | 0.72274556 |
45 | MAP3K5 | 0.71230457 |
46 | PRKAA2 | 0.68411754 |
47 | EEF2K | 0.65922042 |
48 | CAMK1 | 0.64656550 |
49 | ROCK2 | 0.61189955 |
50 | MAP2K3 | 0.60684712 |
51 | CAMK4 | 0.60432489 |
52 | DYRK1B | 0.59865758 |
53 | PKN1 | 0.59492301 |
54 | MAP3K4 | 0.58941662 |
55 | STK38 | 0.57971736 |
56 | MAPK4 | 0.54940391 |
57 | KSR1 | 0.54930880 |
58 | PLK2 | 0.53215163 |
59 | LIMK1 | 0.52947868 |
60 | WNK1 | 0.52814616 |
61 | CAMK2G | 0.52643217 |
62 | PRKACB | 0.50707248 |
63 | STK4 | 0.49344346 |
64 | PRKCE | 0.46963654 |
65 | STK39 | 0.46583703 |
66 | PRKACA | 0.46359455 |
67 | MAPKAPK3 | 0.46109896 |
68 | NTRK3 | 0.45458244 |
69 | PRKD3 | 0.43725088 |
70 | PDGFRA | 0.43673836 |
71 | AKT2 | 0.43230796 |
72 | MAP3K10 | 0.42618536 |
73 | SGK1 | 0.41984500 |
74 | TGFBR2 | 0.40021539 |
75 | FLT3 | 0.39954647 |
76 | PRKG1 | 0.39772445 |
77 | TNIK | 0.39581999 |
78 | BLK | 0.39049953 |
79 | RIPK1 | 0.38659039 |
80 | KSR2 | 0.37601078 |
81 | EPHB2 | 0.36793231 |
82 | RPS6KC1 | 0.35135769 |
83 | RPS6KL1 | 0.35135769 |
84 | FER | 0.32974269 |
85 | MAP3K6 | 0.32060901 |
86 | MAP2K1 | 0.31366450 |
87 | PNCK | 0.30868255 |
88 | MOS | 0.30500028 |
89 | MAP2K6 | 0.28245896 |
90 | PRKACG | 0.27741521 |
91 | BMPR2 | 0.26337110 |
92 | PAK6 | 0.26134647 |
93 | PRPF4B | 0.26105144 |
94 | SGK2 | 0.25480543 |
95 | MAPK7 | 0.25278195 |
96 | RPS6KA3 | 0.25253576 |
97 | CAMK2B | 0.25161428 |
98 | LATS2 | 0.24969692 |
99 | MAP3K3 | 0.24675019 |
100 | RPS6KA6 | 0.24211617 |
101 | PDPK1 | 0.23879174 |
102 | UHMK1 | 0.23150297 |
103 | MAPK10 | 0.22276004 |
104 | ICK | 0.21563435 |
105 | SGK3 | 0.21527776 |
106 | MTOR | 0.21219331 |
107 | PDK1 | 0.19016510 |
108 | MAPK11 | 0.18818472 |
109 | NEK9 | 0.18419102 |
110 | RPS6KA1 | 0.17933701 |
111 | RPS6KA2 | 0.17728180 |
112 | PRKCH | 0.17515402 |
113 | RAF1 | 0.14546875 |
114 | STK11 | 0.14163554 |
115 | LATS1 | 0.14072355 |
116 | AKT3 | 0.13904690 |
117 | SGK223 | 0.13606557 |
118 | SGK494 | 0.13606557 |
119 | RPS6KB1 | 0.13260917 |
120 | EPHA3 | 0.12229648 |
121 | DDR2 | 0.11455390 |
122 | SIK1 | 0.10368958 |
123 | MARK2 | 0.10327760 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 5.19658476 |
2 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 4.74413508 |
3 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 4.09116841 |
4 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 4.02571414 |
5 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.38843200 |
6 | Parkinsons disease_Homo sapiens_hsa05012 | 3.21009329 |
7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.12124975 |
8 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.86865297 |
9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.53789891 |
10 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.35418995 |
11 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 2.28984188 |
12 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.19136508 |
13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.12758425 |
14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.96924389 |
15 | Carbon metabolism_Homo sapiens_hsa01200 | 1.92075413 |
16 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.85618048 |
17 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.51405287 |
18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.46532682 |
19 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.42647912 |
20 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.41376020 |
21 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.37938804 |
22 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.36293909 |
23 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.34632571 |
24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.29300022 |
25 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.29169451 |
26 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.22477333 |
27 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.16404522 |
28 | Circadian entrainment_Homo sapiens_hsa04713 | 1.14247098 |
29 | Renin secretion_Homo sapiens_hsa04924 | 1.08968786 |
30 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.08171632 |
31 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.07321957 |
32 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.04878007 |
33 | Insulin resistance_Homo sapiens_hsa04931 | 0.99913850 |
34 | Tight junction_Homo sapiens_hsa04530 | 0.94186163 |
35 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.93222718 |
36 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.90310195 |
37 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.89034892 |
38 | Insulin secretion_Homo sapiens_hsa04911 | 0.88633410 |
39 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.88373841 |
40 | Olfactory transduction_Homo sapiens_hsa04740 | 0.86906830 |
41 | Focal adhesion_Homo sapiens_hsa04510 | 0.86288941 |
42 | Long-term potentiation_Homo sapiens_hsa04720 | 0.84737915 |
43 | Circadian rhythm_Homo sapiens_hsa04710 | 0.82750266 |
44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.81597964 |
45 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.79070602 |
46 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.78717003 |
47 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.76260871 |
48 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.75680677 |
49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.73393859 |
50 | Taste transduction_Homo sapiens_hsa04742 | 0.71687007 |
51 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.71066886 |
52 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.69319686 |
53 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.69315979 |
54 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.68069566 |
55 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.67161643 |
56 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.64447650 |
57 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.62464829 |
58 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.62182828 |
59 | Adherens junction_Homo sapiens_hsa04520 | 0.60105601 |
60 | Morphine addiction_Homo sapiens_hsa05032 | 0.58577227 |
61 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.58074637 |
62 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.57502411 |
63 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56426954 |
64 | Salivary secretion_Homo sapiens_hsa04970 | 0.55948400 |
65 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.55288423 |
66 | Gap junction_Homo sapiens_hsa04540 | 0.55099382 |
67 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.54132774 |
68 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.53521642 |
69 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.52309939 |
70 | GABAergic synapse_Homo sapiens_hsa04727 | 0.50422945 |
71 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.49893965 |
72 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.49666808 |
73 | Galactose metabolism_Homo sapiens_hsa00052 | 0.48493375 |
74 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.48374938 |
75 | Melanogenesis_Homo sapiens_hsa04916 | 0.45725765 |
76 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.43544252 |
77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.42658117 |
78 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.40110967 |
79 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.37594409 |
80 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.36673067 |
81 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.36050521 |
82 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.35401343 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.35270283 |
84 | Lysine degradation_Homo sapiens_hsa00310 | 0.34301572 |
85 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.33667449 |
86 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.33523237 |
87 | Bile secretion_Homo sapiens_hsa04976 | 0.33521138 |
88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.33302559 |
89 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.33215339 |
90 | Nicotine addiction_Homo sapiens_hsa05033 | 0.32647383 |
91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.32460370 |
92 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.32171922 |
93 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.32042275 |
94 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.30299107 |
95 | Amoebiasis_Homo sapiens_hsa05146 | 0.30197890 |
96 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.30109301 |
97 | Long-term depression_Homo sapiens_hsa04730 | 0.29954776 |
98 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.27394194 |
99 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.25926895 |
100 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.25917002 |
101 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.25730204 |
102 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.25377738 |
103 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25221691 |
104 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.25092401 |
105 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.24291937 |
106 | Endometrial cancer_Homo sapiens_hsa05213 | 0.23898109 |
107 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.23686899 |
108 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.23248306 |
109 | Axon guidance_Homo sapiens_hsa04360 | 0.22821315 |
110 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.21709525 |
111 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.21591367 |
112 | Glioma_Homo sapiens_hsa05214 | 0.21268990 |
113 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.20901005 |
114 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.20583595 |
115 | Platelet activation_Homo sapiens_hsa04611 | 0.20238560 |
116 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.19793404 |
117 | Cocaine addiction_Homo sapiens_hsa05030 | 0.16441814 |
118 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.15535670 |