RBM38

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1oxygen transport (GO:0015671)5.60681464
2negative regulation of cell killing (GO:0031342)4.87803038
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.87803038
4protoporphyrinogen IX metabolic process (GO:0046501)4.70189205
5gas transport (GO:0015669)4.64080033
6negative regulation of erythrocyte differentiation (GO:0045647)4.57367379
7positive thymic T cell selection (GO:0045059)4.51741001
8regulation of B cell receptor signaling pathway (GO:0050855)4.43197412
9protoporphyrinogen IX biosynthetic process (GO:0006782)4.20901080
10antigen processing and presentation of endogenous antigen (GO:0019883)4.15186861
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.12907897
12modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.11597683
13positive regulation by organism of defense response of other organism involved in symbiotic interact4.11597683
14modulation by symbiont of host immune response (GO:0052553)4.11597683
15positive regulation by symbiont of host defense response (GO:0052509)4.11597683
16modulation by symbiont of host defense response (GO:0052031)4.11597683
17modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.11597683
18B cell receptor signaling pathway (GO:0050853)4.07388381
19regulation of gamma-delta T cell activation (GO:0046643)4.02869647
20mitotic chromosome condensation (GO:0007076)4.01240544
21erythrocyte maturation (GO:0043249)4.00990167
22thymic T cell selection (GO:0045061)4.00964103
23mitotic sister chromatid segregation (GO:0000070)3.97579202
24hemoglobin metabolic process (GO:0020027)3.96644541
25tolerance induction (GO:0002507)3.94210404
26porphyrin-containing compound biosynthetic process (GO:0006779)3.93839540
27positive T cell selection (GO:0043368)3.90859356
28heme biosynthetic process (GO:0006783)3.90260699
29modulation by virus of host process (GO:0019054)3.85922063
30leukocyte aggregation (GO:0070486)3.85798881
31detection of bacterium (GO:0016045)3.82421114
32positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.80484979
33detection of other organism (GO:0098543)3.73737900
34DNA replication initiation (GO:0006270)3.69876499
35ribosomal small subunit assembly (GO:0000028)3.68473581
36protein localization to chromosome, centromeric region (GO:0071459)3.67422467
37protein localization to kinetochore (GO:0034501)3.66862919
38T cell selection (GO:0045058)3.66443169
39negative thymic T cell selection (GO:0045060)3.65121662
40DNA replication checkpoint (GO:0000076)3.61907423
41DNA strand elongation involved in DNA replication (GO:0006271)3.61488384
42mitotic metaphase plate congression (GO:0007080)3.59975602
43neutrophil activation involved in immune response (GO:0002283)3.55695474
44DNA deamination (GO:0045006)3.52539306
45negative T cell selection (GO:0043383)3.52305955
46modulation by symbiont of host cellular process (GO:0044068)3.51534525
47regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.50610126
48telomere maintenance via semi-conservative replication (GO:0032201)3.47788687
49meiotic chromosome segregation (GO:0045132)3.47340781
50DNA strand elongation (GO:0022616)3.46538489
51tetrapyrrole biosynthetic process (GO:0033014)3.45453750
52erythrocyte development (GO:0048821)3.43735416
53cellular response to virus (GO:0098586)3.41951502
54positive regulation of B cell differentiation (GO:0045579)3.38974950
55sister chromatid segregation (GO:0000819)3.38863396
56mitotic nuclear envelope disassembly (GO:0007077)3.35437796
57positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.32047148
58response to interleukin-15 (GO:0070672)3.30079571
59positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.27698429
60germinal center formation (GO:0002467)3.27167161
61response to muramyl dipeptide (GO:0032495)3.22267529
62negative regulation of necroptotic process (GO:0060546)3.21112372
63regulation of necroptotic process (GO:0060544)3.20719465
64metaphase plate congression (GO:0051310)3.19695350
65regulation of B cell differentiation (GO:0045577)3.19102728
66DNA replication-dependent nucleosome assembly (GO:0006335)3.18592139
67DNA replication-dependent nucleosome organization (GO:0034723)3.18592139
68viral transcription (GO:0019083)3.18297941
69regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.18159056
70B cell homeostasis (GO:0001782)3.16040056
71DNA unwinding involved in DNA replication (GO:0006268)3.15522322
72negative regulation of histone methylation (GO:0031061)3.14871115
73regulation of histone H3-K27 methylation (GO:0061085)3.14723102
74histone H3-K36 demethylation (GO:0070544)3.13910689
753-UTR-mediated mRNA stabilization (GO:0070935)3.10988944
76DNA replication-independent nucleosome organization (GO:0034724)3.10539921
77DNA replication-independent nucleosome assembly (GO:0006336)3.10539921
78CENP-A containing nucleosome assembly (GO:0034080)3.08962364
79telomere maintenance via recombination (GO:0000722)3.08753460
80chromatin assembly or disassembly (GO:0006333)3.08723459
81NIK/NF-kappaB signaling (GO:0038061)3.08709470
82membrane disassembly (GO:0030397)3.08426125
83nuclear envelope disassembly (GO:0051081)3.08426125
84negative regulation of lymphocyte mediated immunity (GO:0002707)3.08351209
85negative regulation of phagocytosis (GO:0050765)3.07722256
86kinetochore organization (GO:0051383)3.07712440
87regulation of exit from mitosis (GO:0007096)3.07710242
88translational termination (GO:0006415)3.07037879
89lymphocyte homeostasis (GO:0002260)3.06775875
90response to peptidoglycan (GO:0032494)3.06317900
91macrophage activation involved in immune response (GO:0002281)3.05345467
92hepatocyte apoptotic process (GO:0097284)3.05317969
93positive regulation of Rap GTPase activity (GO:0032854)3.04496296
94positive regulation of DNA-dependent DNA replication (GO:2000105)3.02510863
95regulation of granulocyte differentiation (GO:0030852)3.02197699
96establishment of chromosome localization (GO:0051303)3.01719836
97chromatin remodeling at centromere (GO:0031055)3.00961554
98T cell migration (GO:0072678)2.99949905
99regulation of chromatin binding (GO:0035561)2.98800180
100cellular extravasation (GO:0045123)2.97966250
101positive regulation of granulocyte differentiation (GO:0030854)2.96852259
102kinetochore assembly (GO:0051382)2.96421755
103regulation of platelet aggregation (GO:0090330)2.95754029
104attachment of spindle microtubules to kinetochore (GO:0008608)2.95751344
105folic acid-containing compound biosynthetic process (GO:0009396)2.95512875
106protein localization to chromosome (GO:0034502)2.92465548
107protein K6-linked ubiquitination (GO:0085020)2.90602739
108megakaryocyte development (GO:0035855)2.90300204
109translational elongation (GO:0006414)2.90091311
110regulation of interferon-beta biosynthetic process (GO:0045357)2.89588729
111positive regulation of gamma-delta T cell activation (GO:0046645)2.89477457
112response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.89180710
113response to host immune response (GO:0052572)2.89180710
114IMP metabolic process (GO:0046040)2.87682792
115negative regulation of leukocyte mediated immunity (GO:0002704)2.85177014
116Peyers patch development (GO:0048541)2.84486090
117mucosal-associated lymphoid tissue development (GO:0048537)2.84486090
118maturation of 5.8S rRNA (GO:0000460)2.84463539
119porphyrin-containing compound metabolic process (GO:0006778)2.84254159
120T cell homeostasis (GO:0043029)2.83542215
121negative regulation of T cell mediated immunity (GO:0002710)2.83052462
122detection of external biotic stimulus (GO:0098581)2.81990896
123mitotic recombination (GO:0006312)2.80845668
124regulation of spindle organization (GO:0090224)2.80661480
125maturation of SSU-rRNA (GO:0030490)2.80417728
126cellular response to interleukin-15 (GO:0071350)2.80012221
127antigen receptor-mediated signaling pathway (GO:0050851)2.78262642
128neutrophil activation (GO:0042119)2.77770974
129negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.77755207
130IMP biosynthetic process (GO:0006188)2.77482270
131respiratory burst (GO:0045730)2.76827229
132immunoglobulin mediated immune response (GO:0016064)2.75990489
133regulation of mast cell degranulation (GO:0043304)2.75488423
134telomere maintenance via telomere lengthening (GO:0010833)2.74889458
135response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.74844027
136response to host (GO:0075136)2.74844027
137response to host defenses (GO:0052200)2.74844027
138chromosome segregation (GO:0007059)2.74246819
139natural killer cell differentiation (GO:0001779)2.73776152
140CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.72117202
141heme metabolic process (GO:0042168)2.72062913
142nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.71940315
143maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.70918241
144negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.70796437
145ribosomal small subunit biogenesis (GO:0042274)2.70235108
146regulation of alpha-beta T cell proliferation (GO:0046640)2.67060220
147* DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.65642898
148positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.64770027
149leukocyte homeostasis (GO:0001776)2.64326947
150* DNA damage response, signal transduction resulting in transcription (GO:0042772)2.64325631
151granulocyte activation (GO:0036230)2.64205216
152negative regulation of cAMP-mediated signaling (GO:0043951)2.63448031
153translational initiation (GO:0006413)2.62881594
154regulation of telomere maintenance via telomerase (GO:0032210)2.61229363
155positive regulation of protein homooligomerization (GO:0032464)2.61093498
156regulation of sister chromatid cohesion (GO:0007063)2.59346903
157nucleotide-excision repair, DNA gap filling (GO:0006297)2.58922499
158nuclear envelope organization (GO:0006998)2.58628352
159positive regulation of chromosome segregation (GO:0051984)2.56802305
160regulation of gamma-delta T cell differentiation (GO:0045586)2.55245367
161definitive hemopoiesis (GO:0060216)2.53964261
162myeloid cell development (GO:0061515)2.52636776
163regulation of chromosome segregation (GO:0051983)2.51265431
164chromatin assembly (GO:0031497)2.51178915
165embryonic hemopoiesis (GO:0035162)2.49659595
166dosage compensation (GO:0007549)2.49432024
167histone exchange (GO:0043486)2.48134826
168regulation of RIG-I signaling pathway (GO:0039535)2.46357663
169negative regulation of DNA-templated transcription, elongation (GO:0032785)2.44349716
170negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.44349716
171deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.42979019
172negative regulation of telomere maintenance (GO:0032205)2.39611930
173regulation of mitotic spindle organization (GO:0060236)2.39470236
174granulocyte differentiation (GO:0030851)2.38551894
175mitotic sister chromatid cohesion (GO:0007064)2.38287793
176negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.38090208
177negative regulation of chromosome segregation (GO:0051985)2.38081111
178nuclear-transcribed mRNA catabolic process (GO:0000956)2.37973517
179RNA catabolic process (GO:0006401)2.37628238
180antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.37414987
181antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.37414987
182spindle checkpoint (GO:0031577)2.36661377
183regulation of erythrocyte differentiation (GO:0045646)2.35744966
184erythrocyte differentiation (GO:0030218)2.35671766
185viral life cycle (GO:0019058)2.35484296

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.28871299
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.62834300
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.90505019
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.25670801
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.09743428
6* MYC_22102868_ChIP-Seq_BL_Human3.02763472
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.88053643
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.66544406
9* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.51925609
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.40485734
11VDR_21846776_ChIP-Seq_THP-1_Human2.22932456
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.12493570
13* SCL_19346495_ChIP-Seq_HPC-7_Human2.12446074
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.12128736
15* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.99967197
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.99767776
17* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.97739004
18MYC_19079543_ChIP-ChIP_MESCs_Mouse1.90329573
19* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.89614739
20STAT6_21828071_ChIP-Seq_BEAS2B_Human1.89124063
21CIITA_25753668_ChIP-Seq_RAJI_Human1.88336523
22LXR_22292898_ChIP-Seq_THP-1_Human1.86586941
23* RUNX_20019798_ChIP-Seq_JUKART_Human1.85040637
24E2F1_21310950_ChIP-Seq_MCF-7_Human1.83855108
25EST1_17652178_ChIP-ChIP_JURKAT_Human1.82501406
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.81552995
27VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.80481767
28ETS1_20019798_ChIP-Seq_JURKAT_Human1.77588119
29VDR_23849224_ChIP-Seq_CD4+_Human1.74286148
30XRN2_22483619_ChIP-Seq_HELA_Human1.74128167
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.71658686
32* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71572335
33SPI1_23127762_ChIP-Seq_K562_Human1.70288079
34JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.69868036
35MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.64935560
36AR_21909140_ChIP-Seq_LNCAP_Human1.63814187
37GABP_17652178_ChIP-ChIP_JURKAT_Human1.63402614
38* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.63331914
39* KDM2B_26808549_Chip-Seq_JURKAT_Human1.62529850
40TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59150324
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57695709
42* GATA2_19941826_ChIP-Seq_K562_Human1.56953113
43FOXP3_21729870_ChIP-Seq_TREG_Human1.55639846
44KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.55223022
45ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.55133006
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.54320827
47MAF_26560356_Chip-Seq_TH1_Human1.53614114
48STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.53045788
49* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.52316147
50IRF8_27001747_Chip-Seq_BMDM_Mouse1.52307484
51EGR1_19374776_ChIP-ChIP_THP-1_Human1.51863703
52HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51778214
53* UTX_26944678_Chip-Seq_JUKART_Human1.51403062
54GATA1_22383799_ChIP-Seq_G1ME_Mouse1.50896734
55* TCF7_22412390_ChIP-Seq_EML_Mouse1.49979622
56CREB1_15753290_ChIP-ChIP_HEK293T_Human1.47787090
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.45838303
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.43844752
59* GABP_19822575_ChIP-Seq_HepG2_Human1.43746128
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.42536294
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.42000046
62MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.41969201
63MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.41953052
64HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41730575
65* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.41561343
66RACK7_27058665_Chip-Seq_MCF-7_Human1.39211237
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37815560
68MYCN_18555785_ChIP-Seq_MESCs_Mouse1.37500000
69NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.37254511
70CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.37165363
71ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36901503
72IRF8_21731497_ChIP-ChIP_J774_Mouse1.35311356
73DCP1A_22483619_ChIP-Seq_HELA_Human1.35072094
74* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.34457914
75STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.33662971
76DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32645921
77* GATA1_19941827_ChIP-Seq_MEL_Mouse1.32072837
78GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30933140
79* KDM2B_26808549_Chip-Seq_K562_Human1.30920261
80* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.30736254
81KDM5A_27292631_Chip-Seq_BREAST_Human1.30111124
82IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.27132147
83MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25890823
84ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24134512
85* SA1_27219007_Chip-Seq_ERYTHROID_Human1.24123009
86P68_20966046_ChIP-Seq_HELA_Human1.23933507
87* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.23586052
88PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.23548549
89IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.23461063
90* SPI1_23547873_ChIP-Seq_NB4_Human1.22334005
91BCOR_27268052_Chip-Seq_Bcells_Human1.22201942
92PU.1_20513432_ChIP-Seq_Bcells_Mouse1.22133588
93* MYB_26560356_Chip-Seq_TH2_Human1.22086966
94* RUNX1_22412390_ChIP-Seq_EML_Mouse1.22043223
95GATA3_27048872_Chip-Seq_THYMUS_Human1.21900926
96CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.21700520
97MYB_26560356_Chip-Seq_TH1_Human1.20214893
98TTF2_22483619_ChIP-Seq_HELA_Human1.19946100
99MAF_26560356_Chip-Seq_TH2_Human1.18928425
100SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.18864979
101BP1_19119308_ChIP-ChIP_Hs578T_Human1.18547327
102SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.18134210
103ELF1_20517297_ChIP-Seq_JURKAT_Human1.18001197
104GATA2_22383799_ChIP-Seq_G1ME_Mouse1.17594068
105STAT3_1855785_ChIP-Seq_MESCs_Mouse1.17156977
106RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16697652
107* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.15961036
108FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.15823518
109PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14461729
110* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.14322971
111GATA1_22025678_ChIP-Seq_K562_Human1.14222635
112* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.13082119
113BCL6_27268052_Chip-Seq_Bcells_Human1.12948604
114VDR_24763502_ChIP-Seq_THP-1_Human1.10775839
115TP63_19390658_ChIP-ChIP_HaCaT_Human1.10708229
116* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10424224
117SRF_21415370_ChIP-Seq_HL-1_Mouse1.10306291
118NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.09965270
119* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.09495262
120PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09010125
121* GATA1_19941826_ChIP-Seq_K562_Human1.08653812
122* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08609770
123* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08436208
124E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08193109
125* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.07982124
126STAT4_19710469_ChIP-ChIP_TH1__Mouse1.06307668
127* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.05594698
128ELK3_25401928_ChIP-Seq_HUVEC_Human1.05501444
129* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04814283
130POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.03738250
131GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03686919
132CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03592650
133* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.02725674
134PU_27001747_Chip-Seq_BMDM_Mouse1.02257299
135* KDM2B_26808549_Chip-Seq_DND41_Human1.02187404
136CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01940544
137BRD4_27068464_Chip-Seq_AML-cells_Mouse1.01169463
138RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99506816
139GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.98614715
140YY1_21170310_ChIP-Seq_MESCs_Mouse0.98219857
141KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.98202065
142* CTCF_21964334_Chip-Seq_Bcells_Human0.97552619
143* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.97429694
144TFEB_21752829_ChIP-Seq_HELA_Human0.96917954
145SMC4_20622854_ChIP-Seq_HELA_Human0.96652769
146RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96416446
147SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96328699
148NCOR1_26117541_ChIP-Seq_K562_Human0.95931976
149CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.95807243
150CREB1_26743006_Chip-Seq_LNCaP_Human0.95536118
151* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.95358579
152EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93571642

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003656_abnormal_erythrocyte_physiolo4.01816434
2MP0003693_abnormal_embryo_hatching3.67133250
3MP0003303_peritoneal_inflammation3.63649118
4MP0003646_muscle_fatigue3.56473514
5MP0003111_abnormal_nucleus_morphology3.45939085
6MP0010094_abnormal_chromosome_stability3.30117977
7MP0003077_abnormal_cell_cycle3.20172018
8MP0004957_abnormal_blastocyst_morpholog2.87079150
9MP0002396_abnormal_hematopoietic_system2.82439271
10MP0004147_increased_porphyrin_level2.76342889
11MP0008260_abnormal_autophagy2.71676133
12MP0003763_abnormal_thymus_physiology2.30759177
13MP0005397_hematopoietic_system_phenotyp2.26479373
14MP0001545_abnormal_hematopoietic_system2.26479373
15MP0008057_abnormal_DNA_replication2.20110492
16MP0005083_abnormal_biliary_tract2.13857781
17MP0003300_gastrointestinal_ulcer2.10410803
18MP0004808_abnormal_hematopoietic_stem2.09654365
19MP0000490_abnormal_crypts_of2.03148575
20MP0002419_abnormal_innate_immunity2.01428179
21MP0002398_abnormal_bone_marrow2.00867244
22MP0000685_abnormal_immune_system2.00635232
23MP0003724_increased_susceptibility_to2.00135003
24MP0008058_abnormal_DNA_repair1.91157586
25MP0002722_abnormal_immune_system1.74799352
26MP0000689_abnormal_spleen_morphology1.73980490
27MP0008007_abnormal_cellular_replicative1.70677742
28MP0000350_abnormal_cell_proliferation1.67244203
29MP0000703_abnormal_thymus_morphology1.65779262
30MP0005671_abnormal_response_to1.64345406
31MP0004947_skin_inflammation1.64018026
32MP0009333_abnormal_splenocyte_physiolog1.62685401
33MP0005451_abnormal_body_composition1.56489403
34MP0002019_abnormal_tumor_incidence1.54868868
35MP0008877_abnormal_DNA_methylation1.53891409
36MP0003191_abnormal_cellular_cholesterol1.53112484
37MP0001730_embryonic_growth_arrest1.52106350
38MP0003172_abnormal_lysosome_physiology1.50741053
39MP0005076_abnormal_cell_differentiation1.49695245
40MP0004381_abnormal_hair_follicle1.47272969
41MP0002429_abnormal_blood_cell1.46700720
42MP0009278_abnormal_bone_marrow1.45999889
43MP0004084_abnormal_cardiac_muscle1.45022892
44MP0001800_abnormal_humoral_immune1.42955967
45MP0000749_muscle_degeneration1.38557793
46MP0000716_abnormal_immune_system1.37567163
47MP0000313_abnormal_cell_death1.34522013
48MP0004510_myositis1.32490480
49MP0001697_abnormal_embryo_size1.31367263
50MP0004130_abnormal_muscle_cell1.29263312
51MP0002405_respiratory_system_inflammati1.27774425
52MP0010307_abnormal_tumor_latency1.27283793
53MP0002653_abnormal_ependyma_morphology1.27039464
54MP0002148_abnormal_hypersensitivity_rea1.25706092
55MP0001845_abnormal_inflammatory_respons1.24969123
56MP0008932_abnormal_embryonic_tissue1.24825470
57MP0006036_abnormal_mitochondrial_physio1.24212107
58MP0002420_abnormal_adaptive_immunity1.23652873
59MP0005380_embryogenesis_phenotype1.22506639
60MP0001672_abnormal_embryogenesis/_devel1.22506639
61MP0003221_abnormal_cardiomyocyte_apopto1.22088185
62MP0001819_abnormal_immune_cell1.21183469
63MP0003984_embryonic_growth_retardation1.20978556
64MP0003123_paternal_imprinting1.19170201
65MP0002009_preneoplasia1.19151357
66MP0002088_abnormal_embryonic_growth/wei1.17181183
67MP0002080_prenatal_lethality1.16909013
68MP0001835_abnormal_antigen_presentation1.16402186
69MP0002138_abnormal_hepatobiliary_system1.14250089
70MP0003786_premature_aging1.12687201
71MP0010630_abnormal_cardiac_muscle1.12310239
72MP0002452_abnormal_antigen_presenting1.12091660
73MP0003718_maternal_effect1.11881478
74MP0005464_abnormal_platelet_physiology1.11201964
75MP0001533_abnormal_skeleton_physiology1.10294434
76MP0002723_abnormal_immune_serum1.08084217
77MP0003567_abnormal_fetal_cardiomyocyte1.07890676
78MP0002086_abnormal_extraembryonic_tissu1.07720372
79MP0010352_gastrointestinal_tract_polyps1.07131329
80MP0002106_abnormal_muscle_physiology1.04665366
81MP0005075_abnormal_melanosome_morpholog1.04631422
82MP0002332_abnormal_exercise_endurance1.04106397
83MP0004087_abnormal_muscle_fiber1.04014730
84MP0005330_cardiomyopathy1.03905067
85MP0001873_stomach_inflammation1.03269428
86MP0002132_abnormal_respiratory_system1.02891705
87MP0000465_gastrointestinal_hemorrhage1.02199041
88MP0008775_abnormal_heart_ventricle1.01781907
89MP0002837_dystrophic_cardiac_calcinosis1.01771181
90MP0003828_pulmonary_edema1.01606867
91MP0001851_eye_inflammation1.00589217
92MP0004036_abnormal_muscle_relaxation0.99164927
93MP0002085_abnormal_embryonic_tissue0.98576370
94MP0005387_immune_system_phenotype0.97513297
95MP0001790_abnormal_immune_system0.97513297
96MP0008995_early_reproductive_senescence0.97048273
97MP0004185_abnormal_adipocyte_glucose0.95679609
98MP0003453_abnormal_keratinocyte_physiol0.95576208
99MP0004215_abnormal_myocardial_fiber0.95065664
100MP0010155_abnormal_intestine_physiology0.94282244
101MP0002269_muscular_atrophy0.93604242
102MP0005025_abnormal_response_to0.93371699
103MP0002102_abnormal_ear_morphology0.92742945
104MP0006082_CNS_inflammation0.91418889
105MP0005000_abnormal_immune_tolerance0.89977332
106MP0001853_heart_inflammation0.89612000
107MP0004233_abnormal_muscle_weight0.89544006
108MP0000750_abnormal_muscle_regeneration0.88791984
109MP0003045_fibrosis0.88673217
110MP0000759_abnormal_skeletal_muscle0.88433197
111MP0009785_altered_susceptibility_to0.87661468
112MP0002166_altered_tumor_susceptibility0.87398366
113MP0009840_abnormal_foam_cell0.87395234
114MP0002084_abnormal_developmental_patter0.87339928
115MP0005310_abnormal_salivary_gland0.87181597
116MP0005058_abnormal_lysosome_morphology0.87009264
117MP0008469_abnormal_protein_level0.86765053
118MP0001119_abnormal_female_reproductive0.85495267
119MP0000747_muscle_weakness0.85356839
120MP0003436_decreased_susceptibility_to0.84362599
121MP0001663_abnormal_digestive_system0.83627649
122MP0001929_abnormal_gametogenesis0.83516560
123MP0002210_abnormal_sex_determination0.82628598
124MP0000266_abnormal_heart_morphology0.80758920
125MP0000751_myopathy0.79399439
126MP0003866_abnormal_defecation0.78711473
127MP0000343_altered_response_to0.78087721
128MP0002006_tumorigenesis0.77984383
129MP0003183_abnormal_peptide_metabolism0.76860192
130MP0000858_altered_metastatic_potential0.76614545
131MP0002998_abnormal_bone_remodeling0.75977336
132MP0001544_abnormal_cardiovascular_syste0.75896827
133MP0005385_cardiovascular_system_phenoty0.75896827
134MP0004145_abnormal_muscle_electrophysio0.72925401
135MP0005666_abnormal_adipose_tissue0.72922887
136MP0009764_decreased_sensitivity_to0.69159545
137MP0008874_decreased_physiological_sensi0.69152662
138MP0009931_abnormal_skin_appearance0.67272394
139MP0002933_joint_inflammation0.64877830
140MP0005621_abnormal_cell_physiology0.64294006
141MP0003091_abnormal_cell_migration0.63903848
142MP0000015_abnormal_ear_pigmentation0.61860871
143MP0008961_abnormal_basal_metabolism0.61203333
144MP0000609_abnormal_liver_physiology0.59610125

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the heme biosynthetic pathway (HP:0010472)6.39166938
2Poikilocytosis (HP:0004447)4.81435804
3Eczematoid dermatitis (HP:0000976)4.76901610
4Abnormal number of erythroid precursors (HP:0012131)4.33584989
5Abnormality of cells of the erythroid lineage (HP:0012130)4.17495164
6Birth length less than 3rd percentile (HP:0003561)4.03254916
7Recurrent bacterial skin infections (HP:0005406)3.72371276
8Recurrent abscess formation (HP:0002722)3.70809088
9Abnormality of the fingertips (HP:0001211)3.62853750
10Aplastic anemia (HP:0001915)3.56726870
11Gastrointestinal infarctions (HP:0005244)3.40085720
12Reticulocytosis (HP:0001923)3.39317434
13Meningitis (HP:0001287)3.30983678
14Abnormality of macrophages (HP:0004311)3.25065241
15Abnormality of reticulocytes (HP:0004312)3.19498229
16IgM deficiency (HP:0002850)3.11044171
17Acanthocytosis (HP:0001927)3.09429753
18Gastrointestinal inflammation (HP:0004386)3.08224647
19Obstructive lung disease (HP:0006536)3.05035905
20Chronic obstructive pulmonary disease (HP:0006510)3.05035905
21Exercise-induced myalgia (HP:0003738)3.05025178
22Abnormal hemoglobin (HP:0011902)3.02067298
23Inflammation of the large intestine (HP:0002037)3.00463983
24Mediastinal lymphadenopathy (HP:0100721)2.93319691
25Chromsome breakage (HP:0040012)2.92365065
26Thrombocytosis (HP:0001894)2.91334280
27Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.89383094
28Gastrointestinal stroma tumor (HP:0100723)2.89048028
29Spontaneous hematomas (HP:0007420)2.87274680
30Increased IgE level (HP:0003212)2.86500936
31Vasculitis (HP:0002633)2.84678889
32Reticulocytopenia (HP:0001896)2.84264086
33Myopathic facies (HP:0002058)2.83037608
34Colitis (HP:0002583)2.81563428
35Muscle fiber inclusion bodies (HP:0100299)2.81500311
36Myelodysplasia (HP:0002863)2.79909907
37Osteomyelitis (HP:0002754)2.77687303
38Stomatitis (HP:0010280)2.76889825
39Subaortic stenosis (HP:0001682)2.75786437
40Abnormality of the left ventricular outflow tract (HP:0011103)2.75786437
41Basal cell carcinoma (HP:0002671)2.74995570
42Urticaria (HP:0001025)2.74542511
43Centrally nucleated skeletal muscle fibers (HP:0003687)2.72918002
44Slow saccadic eye movements (HP:0000514)2.72201390
45Patellar aplasia (HP:0006443)2.71483868
46Chromosomal breakage induced by crosslinking agents (HP:0003221)2.70529348
47Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.69963043
48Breast hypoplasia (HP:0003187)2.69634215
49Nemaline bodies (HP:0003798)2.68911370
50Ventricular tachycardia (HP:0004756)2.66869739
51Recurrent gram-negative bacterial infections (HP:0005420)2.66460688
52Hypochromic anemia (HP:0001931)2.66170657
53Petechiae (HP:0000967)2.65981279
54Abnormal gallbladder morphology (HP:0012437)2.65572115
55Muscle fiber atrophy (HP:0100295)2.59289763
56Pustule (HP:0200039)2.55354291
57Panhypogammaglobulinemia (HP:0003139)2.52185119
58Difficulty running (HP:0009046)2.51645675
59Recurrent skin infections (HP:0001581)2.50943718
60Hypochromic microcytic anemia (HP:0004840)2.50167908
61Encephalitis (HP:0002383)2.49814919
62Prolonged bleeding time (HP:0003010)2.49557955
63Lymphopenia (HP:0001888)2.48676350
64Cholecystitis (HP:0001082)2.48086301
65Abnormal gallbladder physiology (HP:0012438)2.48086301
66Aplasia/Hypoplasia of the patella (HP:0006498)2.46377633
67Toxemia of pregnancy (HP:0100603)2.46057850
68Microcytic anemia (HP:0001935)2.44529199
69Oral leukoplakia (HP:0002745)2.43641538
70Chest pain (HP:0100749)2.40397478
71Type 2 muscle fiber atrophy (HP:0003554)2.40055470
72Chronic mucocutaneous candidiasis (HP:0002728)2.38699783
73Recurrent cutaneous fungal infections (HP:0011370)2.38699783
74Pallor (HP:0000980)2.35370906
75Abnormality of cells of the lymphoid lineage (HP:0012140)2.35361964
76Fatigue (HP:0012378)2.34368513
77Orchitis (HP:0100796)2.33574972
78Combined immunodeficiency (HP:0005387)2.33444430
79Multiple enchondromatosis (HP:0005701)2.32888197
80Gingivitis (HP:0000230)2.32202270
81Muscle fiber splitting (HP:0003555)2.31083315
82Paralysis (HP:0003470)2.29267085
83Increased IgM level (HP:0003496)2.27767648
84Diaphragmatic weakness (HP:0009113)2.27187562
85Abnormality of chromosome stability (HP:0003220)2.24789396
86Rhabdomyolysis (HP:0003201)2.24365030
87Optic neuritis (HP:0100653)2.22549265
88Retrobulbar optic neuritis (HP:0100654)2.22549265
89Increased connective tissue (HP:0009025)2.20830149
90Abnormality of the preputium (HP:0100587)2.18498114
91Exercise-induced muscle cramps (HP:0003710)2.16483275
92Autoimmune thrombocytopenia (HP:0001973)2.16163882
93Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.16095933
94Decreased activity of mitochondrial respiratory chain (HP:0008972)2.16095933
95Hypertensive crisis (HP:0100735)2.14796353
96Cholelithiasis (HP:0001081)2.14144609
97Prominent nose (HP:0000448)2.12974268
98Abnormality of skeletal muscle fiber size (HP:0012084)2.12419998
99Nasal polyposis (HP:0100582)2.11699727
100Recurrent sinusitis (HP:0011108)2.11626265
101Abnormality of iron homeostasis (HP:0011031)2.10631063
102Abnormality of T cells (HP:0002843)2.10336669
103Lipoatrophy (HP:0100578)2.09490945
104Cafe-au-lait spot (HP:0000957)2.09254809
105Recurrent viral infections (HP:0004429)2.09075325
106Abnormality of the nasal mucosa (HP:0000433)2.08876325
107Autoimmune hemolytic anemia (HP:0001890)2.08696102
108Granulocytopenia (HP:0001913)2.08623783
109Acute myeloid leukemia (HP:0004808)2.07460887
110Aplasia/Hypoplasia of the uvula (HP:0010293)2.06372644
111Recurrent bronchitis (HP:0002837)2.06322039
112Poikiloderma (HP:0001029)2.04767809
113Abnormality of T cell number (HP:0011839)2.04545934
114Cellulitis (HP:0100658)2.03941206
115Myositis (HP:0100614)2.03811806
116Abnormality of the gallbladder (HP:0005264)2.03300396
117Viral hepatitis (HP:0006562)2.03156715
118Meckel diverticulum (HP:0002245)2.01563576
119Abnormal delayed hypersensitivity skin test (HP:0002963)1.99060470
120Carpal bone hypoplasia (HP:0001498)1.98007398
121Restrictive lung disease (HP:0002091)1.97792704
122Lymphoma (HP:0002665)1.97646604
123Abnormality of T cell physiology (HP:0011840)1.97315312
124Abnormality of the ileum (HP:0001549)1.96865337
125Progressive muscle weakness (HP:0003323)1.95210973
126Gingival bleeding (HP:0000225)1.95020137
127Hyporeflexia of lower limbs (HP:0002600)1.94763731
128Leukocytosis (HP:0001974)1.93176626
129Absent thumb (HP:0009777)1.92726758
130Rib fusion (HP:0000902)1.91995212
131Polycythemia (HP:0001901)1.91123366
132Increased serum ferritin (HP:0003281)1.87514014
133Verrucae (HP:0200043)1.87053600
134Papilloma (HP:0012740)1.87053600
135Hyperbilirubinemia (HP:0002904)1.85022841
136High pitched voice (HP:0001620)1.84900406
137Bone marrow hypocellularity (HP:0005528)1.84724068
138Duodenal stenosis (HP:0100867)1.84640435
139Small intestinal stenosis (HP:0012848)1.84640435
140Macrocytic anemia (HP:0001972)1.83856638
141Weak cry (HP:0001612)1.83833601
142IgG deficiency (HP:0004315)1.83824473
143Amaurosis fugax (HP:0100576)1.83713164
144Severe combined immunodeficiency (HP:0004430)1.83503832
145Premature ovarian failure (HP:0008209)1.82744878
146Elevated erythrocyte sedimentation rate (HP:0003565)1.81968357
147Abnormal platelet function (HP:0011869)1.81394094
148Impaired platelet aggregation (HP:0003540)1.81394094
149Microretrognathia (HP:0000308)1.80948369
150Pulmonary fibrosis (HP:0002206)1.80731986
151Selective tooth agenesis (HP:0001592)1.79635922
152T lymphocytopenia (HP:0005403)1.78912346
153Cutaneous photosensitivity (HP:0000992)1.78905555
154Broad palm (HP:0001169)1.78440582
155Clubbing of toes (HP:0100760)1.77431729
156Epistaxis (HP:0000421)1.76718781
157Sudden death (HP:0001699)1.76185177
158Agammaglobulinemia (HP:0004432)1.75461113
159Chronic otitis media (HP:0000389)1.74673765
160Recurrent fungal infections (HP:0002841)1.72664230
161Easy fatigability (HP:0003388)1.70647423
162Ependymoma (HP:0002888)1.70218200
163Ragged-red muscle fibers (HP:0003200)1.69978051

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B4.28919519
2EEF2K4.12979597
3MAP4K13.10022724
4RIPK43.04877099
5CDC72.94381226
6CDK122.59867256
7NEK22.51713686
8TAOK12.30071286
9TAOK22.19790573
10MUSK2.19352051
11SMG12.17903629
12BUB12.16502068
13MAP3K102.16165537
14NME22.10756461
15STK102.09009225
16MAPKAPK32.08620497
17MAP3K32.04349248
18IRAK42.03061857
19EIF2AK12.02928072
20STK41.92119322
21RPS6KB21.86640954
22WEE11.81876634
23PLK41.76760186
24PKN21.73844916
25TTK1.66556835
26SIK11.63363577
27TNK21.63328445
28BLK1.62994911
29SIK31.62146831
30MAP3K61.58487452
31ICK1.45018701
32MAP3K111.44275030
33SIK21.43274092
34MAP2K31.42136828
35JAK31.41822505
36CDK41.41349919
37MAP3K11.38750962
38TRIB31.37999224
39RAF11.36788574
40DYRK31.35343444
41CDK81.33675458
42PIM11.32719617
43FES1.30767561
44CSK1.28926039
45MAP3K81.28593762
46CDK71.26948441
47HCK1.26488899
48AURKB1.25778093
49MARK31.24748073
50GRK61.23707864
51PLK11.21066898
52MAP3K141.19517373
53FLT31.19036142
54TLK11.17488047
55TBK11.17296653
56ZAP701.17163422
57MARK21.15779158
58CHEK21.15728926
59MAPK111.15326281
60ACVR1B1.14544481
61MAPK121.11696974
62TTN1.11150714
63BRSK11.09060285
64VRK11.08877824
65RPS6KA41.06627135
66TAOK31.05315421
67ITK1.02700413
68CDK91.02012424
69KSR21.01520719
70BTK1.00166545
71EPHB10.98341504
72KIT0.98046154
73TRPM70.98032779
74BRSK20.98006658
75TYK20.96466838
76STK240.95773347
77MOS0.95333698
78BMX0.93020324
79ATR0.90940821
80MELK0.89788263
81KDR0.89744629
82FGR0.89581787
83FGFR40.89509319
84SGK30.88310948
85BRAF0.87263142
86OBSCN0.84182728
87TGFBR10.84033635
88TXK0.83787491
89NEK10.82903004
90RPS6KL10.79430931
91RPS6KC10.79430931
92SYK0.78458299
93LRRK20.76090839
94SRPK10.74764373
95IRAK20.74593576
96CHEK10.73303409
97DYRK1B0.73128073
98PDK10.72174918
99PASK0.71119333
100AURKA0.70859287
101IKBKE0.70722196
102IRAK30.69340213
103PRKD20.67866795
104MAP3K130.65010985
105DMPK0.64267207
106TESK20.63868756
107RPS6KA60.63155853
108SGK20.62600533
109TEC0.61797373
110PDPK10.60934347
111STK30.60543956
112RPS6KA50.59940722
113ERN10.59517061
114CSF1R0.59145034
115JAK10.58914364
116NLK0.57793895
117CAMK40.57321745
118MAP2K20.56449145
119ATM0.55409507
120PTK60.53187377
121FGFR30.53056130
122ZAK0.53030660
123BRD40.52965827
124PRKCQ0.52614487
125HIPK20.52432041
126TGFBR20.51180891
127MAP3K50.51146972
128CHUK0.50263738
129CDC42BPA0.49917950
130PIK3CG0.49907571
131PAK40.49422985
132ILK0.48951954
133CAMKK10.47511532
134CDK20.47388258
135IKBKB0.47328844
136IRAK10.46929198
137SCYL20.46136525
138MAPK70.45863692
139LCK0.45214399
140PRKAA10.44743893
141STK110.44402529
142MTOR0.43218569
143BCKDK0.42628061
144LATS10.42355517
145YES10.42334326
146RPS6KA20.41422772
147PTK2B0.40684864
148LYN0.40044842
149PRKAA20.39607923
150CAMK1D0.39570432
151JAK20.38304205
152CDK60.38239137
153MAPKAPK20.37754141
154PIM20.37511925
155MAP3K70.36336212

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.18114054
2Mismatch repair_Homo sapiens_hsa034303.17780587
3Cell cycle_Homo sapiens_hsa041103.10752503
4Base excision repair_Homo sapiens_hsa034103.00231903
5Ribosome_Homo sapiens_hsa030102.63496407
6Homologous recombination_Homo sapiens_hsa034402.44644674
7RNA degradation_Homo sapiens_hsa030182.40756584
8Nucleotide excision repair_Homo sapiens_hsa034202.33050928
9Spliceosome_Homo sapiens_hsa030402.25460266
10RNA polymerase_Homo sapiens_hsa030202.17620022
11RNA transport_Homo sapiens_hsa030132.16651749
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.11232047
13Primary immunodeficiency_Homo sapiens_hsa053402.10295119
14Fanconi anemia pathway_Homo sapiens_hsa034601.87316653
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.84800005
16Pyrimidine metabolism_Homo sapiens_hsa002401.80659653
17p53 signaling pathway_Homo sapiens_hsa041151.80078046
18Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.76789666
19Allograft rejection_Homo sapiens_hsa053301.75758027
20Basal transcription factors_Homo sapiens_hsa030221.74614460
21Non-homologous end-joining_Homo sapiens_hsa034501.69727644
22Systemic lupus erythematosus_Homo sapiens_hsa053221.68861030
23Autoimmune thyroid disease_Homo sapiens_hsa053201.66494803
24Graft-versus-host disease_Homo sapiens_hsa053321.64351142
25Toll-like receptor signaling pathway_Homo sapiens_hsa046201.63469708
26Herpes simplex infection_Homo sapiens_hsa051681.49338272
27mRNA surveillance pathway_Homo sapiens_hsa030151.48525488
28Renal cell carcinoma_Homo sapiens_hsa052111.44408346
29One carbon pool by folate_Homo sapiens_hsa006701.42767447
30Tuberculosis_Homo sapiens_hsa051521.42565478
31Vitamin B6 metabolism_Homo sapiens_hsa007501.25027907
32Neurotrophin signaling pathway_Homo sapiens_hsa047221.24364447
33Chemokine signaling pathway_Homo sapiens_hsa040621.23469792
34Sulfur relay system_Homo sapiens_hsa041221.21417727
35Chronic myeloid leukemia_Homo sapiens_hsa052201.16965697
36Hepatitis C_Homo sapiens_hsa051601.16696308
37Viral carcinogenesis_Homo sapiens_hsa052031.15873813
38Staphylococcus aureus infection_Homo sapiens_hsa051501.15431169
39Measles_Homo sapiens_hsa051621.14762176
40Hematopoietic cell lineage_Homo sapiens_hsa046401.13609897
41Pancreatic cancer_Homo sapiens_hsa052121.12689118
42Acute myeloid leukemia_Homo sapiens_hsa052211.11558275
43TNF signaling pathway_Homo sapiens_hsa046681.11328410
44Transcriptional misregulation in cancer_Homo sapiens_hsa052021.07586145
45Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07165147
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.06547901
47Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.06349625
48Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.05750947
49HTLV-I infection_Homo sapiens_hsa051661.04559695
50B cell receptor signaling pathway_Homo sapiens_hsa046621.03884135
51Epstein-Barr virus infection_Homo sapiens_hsa051691.03043912
52Small cell lung cancer_Homo sapiens_hsa052221.02165634
53Type I diabetes mellitus_Homo sapiens_hsa049401.01929647
54Antigen processing and presentation_Homo sapiens_hsa046121.01684514
55Insulin signaling pathway_Homo sapiens_hsa049101.01414033
56NF-kappa B signaling pathway_Homo sapiens_hsa040640.99988769
57Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.99938424
58African trypanosomiasis_Homo sapiens_hsa051430.99009673
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.98845713
60Prostate cancer_Homo sapiens_hsa052150.97970957
61Hepatitis B_Homo sapiens_hsa051610.97896555
62Thyroid cancer_Homo sapiens_hsa052160.97756279
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.96140527
64Non-small cell lung cancer_Homo sapiens_hsa052230.95929340
65Asthma_Homo sapiens_hsa053100.95119477
66Inositol phosphate metabolism_Homo sapiens_hsa005620.93699111
67Proteasome_Homo sapiens_hsa030500.93349616
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.92796362
69Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.92344374
70Notch signaling pathway_Homo sapiens_hsa043300.90482202
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89516494
72Purine metabolism_Homo sapiens_hsa002300.89151676
73Glioma_Homo sapiens_hsa052140.89001300
74Choline metabolism in cancer_Homo sapiens_hsa052310.88992106
75Insulin resistance_Homo sapiens_hsa049310.88309342
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87644080
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.87053846
78Apoptosis_Homo sapiens_hsa042100.84851679
79Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.80319421
80Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.80284784
81Pentose phosphate pathway_Homo sapiens_hsa000300.79491539
82Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.78724112
83Bladder cancer_Homo sapiens_hsa052190.78166745
84Intestinal immune network for IgA production_Homo sapiens_hsa046720.77851438
85Oocyte meiosis_Homo sapiens_hsa041140.77395893
86MicroRNAs in cancer_Homo sapiens_hsa052060.77040344
87Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.77022516
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76940720
89ErbB signaling pathway_Homo sapiens_hsa040120.76847889
90T cell receptor signaling pathway_Homo sapiens_hsa046600.76828823
91Viral myocarditis_Homo sapiens_hsa054160.75729468
92Colorectal cancer_Homo sapiens_hsa052100.74511718
93Leishmaniasis_Homo sapiens_hsa051400.72888564
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72740468
95GnRH signaling pathway_Homo sapiens_hsa049120.72417693
96Sphingolipid signaling pathway_Homo sapiens_hsa040710.71603591
97MAPK signaling pathway_Homo sapiens_hsa040100.71514086
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.71332214
99Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.71227794
100RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68701726
101Regulation of autophagy_Homo sapiens_hsa041400.66991307
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.66304422
103VEGF signaling pathway_Homo sapiens_hsa043700.65404880
104Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65212279
105Shigellosis_Homo sapiens_hsa051310.64193387
106Influenza A_Homo sapiens_hsa051640.63397170
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59726441
108Prolactin signaling pathway_Homo sapiens_hsa049170.59350871
109Biosynthesis of amino acids_Homo sapiens_hsa012300.59104178
110Endocytosis_Homo sapiens_hsa041440.57767046
111Type II diabetes mellitus_Homo sapiens_hsa049300.57615146
112Long-term potentiation_Homo sapiens_hsa047200.56329812
113Folate biosynthesis_Homo sapiens_hsa007900.56229927
114Legionellosis_Homo sapiens_hsa051340.55528889
115Alcoholism_Homo sapiens_hsa050340.55255602
116Platelet activation_Homo sapiens_hsa046110.54812875
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.53137796
118HIF-1 signaling pathway_Homo sapiens_hsa040660.52370292
119Toxoplasmosis_Homo sapiens_hsa051450.51195793
120FoxO signaling pathway_Homo sapiens_hsa040680.51110331
1212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50139341
122Circadian rhythm_Homo sapiens_hsa047100.49469546
123mTOR signaling pathway_Homo sapiens_hsa041500.49430826
124Osteoclast differentiation_Homo sapiens_hsa043800.47618672
125Phagosome_Homo sapiens_hsa041450.46875975
126Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46171572
127Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44756595
128Central carbon metabolism in cancer_Homo sapiens_hsa052300.44157622
129Lysine degradation_Homo sapiens_hsa003100.41559687
130TGF-beta signaling pathway_Homo sapiens_hsa043500.41370530
131Fructose and mannose metabolism_Homo sapiens_hsa000510.38919804
132Carbon metabolism_Homo sapiens_hsa012000.38726203
133Endometrial cancer_Homo sapiens_hsa052130.34731340
134AMPK signaling pathway_Homo sapiens_hsa041520.34607892
135Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33816000
136Leukocyte transendothelial migration_Homo sapiens_hsa046700.33513202
137Malaria_Homo sapiens_hsa051440.33454849
138Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33349796
139Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.32285515
140Galactose metabolism_Homo sapiens_hsa000520.31826299
141Pathways in cancer_Homo sapiens_hsa052000.31634339
142Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.29050411
143Other glycan degradation_Homo sapiens_hsa005110.28688473
144Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28616961

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