RBM4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of integrated proviral latency (GO:0075713)4.49141497
2DNA damage response, detection of DNA damage (GO:0042769)4.27623400
3nuclear pore complex assembly (GO:0051292)4.23761715
4proteasome assembly (GO:0043248)4.10056819
5DNA demethylation (GO:0080111)4.00964450
6microtubule depolymerization (GO:0007019)3.95360442
7nuclear pore organization (GO:0006999)3.92866245
8DNA dealkylation (GO:0035510)3.87352930
9establishment of viral latency (GO:0019043)3.85398599
10DNA double-strand break processing (GO:0000729)3.75748008
11histone H3-K9 methylation (GO:0051567)3.74734321
12neural tube formation (GO:0001841)3.74417241
13polyketide metabolic process (GO:0030638)3.74148942
14doxorubicin metabolic process (GO:0044598)3.74148942
15daunorubicin metabolic process (GO:0044597)3.74148942
16mitotic sister chromatid cohesion (GO:0007064)3.67248820
17histone H2A acetylation (GO:0043968)3.65812745
18kinetochore organization (GO:0051383)3.59060682
19negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.58064854
20histone H3-K4 trimethylation (GO:0080182)3.53486444
21pore complex assembly (GO:0046931)3.51651771
22regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.48006620
23cullin deneddylation (GO:0010388)3.42756237
24DNA ligation (GO:0006266)3.41971242
25positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.39469996
26anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.38081937
27DNA integration (GO:0015074)3.37600909
28histone H3-K9 modification (GO:0061647)3.33792257
29spliceosomal snRNP assembly (GO:0000387)3.33183348
30kinetochore assembly (GO:0051382)3.32392995
31DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.27763815
32cytoplasmic mRNA processing body assembly (GO:0033962)3.27043497
33negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.26996199
34negative regulation of ligase activity (GO:0051352)3.26996199
35signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25142924
36signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25142924
37signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25142924
38DNA strand elongation involved in DNA replication (GO:0006271)3.23885133
39intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.23400261
40signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.23400261
41signal transduction involved in cell cycle checkpoint (GO:0072395)3.19926221
42regulation of cellular amino acid metabolic process (GO:0006521)3.19260632
43RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.19165590
44histone mRNA catabolic process (GO:0071044)3.19018117
45non-recombinational repair (GO:0000726)3.18142921
46double-strand break repair via nonhomologous end joining (GO:0006303)3.18142921
47protein deneddylation (GO:0000338)3.14575499
48signal transduction involved in DNA damage checkpoint (GO:0072422)3.14166900
49signal transduction involved in DNA integrity checkpoint (GO:0072401)3.14166900
50L-serine metabolic process (GO:0006563)3.12491119
51DNA strand elongation (GO:0022616)3.11733845
52positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)3.08867666
53rRNA catabolic process (GO:0016075)3.07339922
54peptidyl-lysine trimethylation (GO:0018023)3.04980341
55establishment of protein localization to mitochondrial membrane (GO:0090151)3.03746229
56regulation of DNA endoreduplication (GO:0032875)3.03690582
57ncRNA catabolic process (GO:0034661)3.01444275
58DNA catabolic process, exonucleolytic (GO:0000738)2.99804191
59positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.99594863
60mismatch repair (GO:0006298)2.99167568
61telomere maintenance via semi-conservative replication (GO:0032201)2.98398352
62pyrimidine dimer repair (GO:0006290)2.98219795
63histone mRNA metabolic process (GO:0008334)2.96945359
64positive regulation of DNA-dependent DNA replication (GO:2000105)2.91492467
65mitotic metaphase plate congression (GO:0007080)2.90248449
66meiotic chromosome segregation (GO:0045132)2.88615779
67rRNA modification (GO:0000154)2.87807651
68respiratory chain complex IV assembly (GO:0008535)2.86395313
69DNA strand renaturation (GO:0000733)2.86026605
70replicative senescence (GO:0090399)2.85706509
71monoubiquitinated protein deubiquitination (GO:0035520)2.85630681
72viral mRNA export from host cell nucleus (GO:0046784)2.84927795
73base-excision repair (GO:0006284)2.83326100
74positive regulation of ligase activity (GO:0051351)2.82909388
75nucleotide-excision repair, DNA gap filling (GO:0006297)2.82882500
76regulation of DNA damage checkpoint (GO:2000001)2.82279131
777-methylguanosine mRNA capping (GO:0006370)2.81275496
78exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.79659562
79histone H3-K4 methylation (GO:0051568)2.78227239
80somatic diversification of immune receptors via somatic mutation (GO:0002566)2.77061291
81somatic hypermutation of immunoglobulin genes (GO:0016446)2.77061291
82DNA replication-independent nucleosome organization (GO:0034724)2.76992980
83DNA replication-independent nucleosome assembly (GO:0006336)2.76992980
84regulation of ubiquitin-protein transferase activity (GO:0051438)2.76920254
85postreplication repair (GO:0006301)2.76555862
86metaphase plate congression (GO:0051310)2.73573491
87CENP-A containing nucleosome assembly (GO:0034080)2.73514787
88regulation of helicase activity (GO:0051095)2.72715012
89histone H3-K36 demethylation (GO:0070544)2.72574390
90RNA localization (GO:0006403)2.72556698
91DNA methylation or demethylation (GO:0044728)2.72515644
92replication fork processing (GO:0031297)2.72337785
93tRNA aminoacylation for protein translation (GO:0006418)2.72278365
94RNA capping (GO:0036260)2.71770240
957-methylguanosine RNA capping (GO:0009452)2.71770240
96dosage compensation (GO:0007549)2.71596457
97mRNA splice site selection (GO:0006376)2.71381936
98tRNA aminoacylation (GO:0043039)2.71299197
99amino acid activation (GO:0043038)2.71299197
100DNA damage response, signal transduction resulting in transcription (GO:0042772)2.71265671
101protein localization to kinetochore (GO:0034501)2.70109230
102ATP-dependent chromatin remodeling (GO:0043044)2.70042925
103transcription-coupled nucleotide-excision repair (GO:0006283)2.69962547
104regulation of mitotic spindle checkpoint (GO:1903504)2.69893503
105regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.69893503
106histone deubiquitination (GO:0016578)2.69542327
107regulation of development, heterochronic (GO:0040034)2.68484383
108metallo-sulfur cluster assembly (GO:0031163)2.68262535
109iron-sulfur cluster assembly (GO:0016226)2.68262535
110spliceosomal complex assembly (GO:0000245)2.67528962
111negative regulation of mRNA processing (GO:0050686)2.67459946
112histone lysine demethylation (GO:0070076)2.67038315
113termination of RNA polymerase III transcription (GO:0006386)2.66933958
114transcription elongation from RNA polymerase III promoter (GO:0006385)2.66933958
115regulation of ligase activity (GO:0051340)2.63789365
116intra-S DNA damage checkpoint (GO:0031573)2.63639309
117protein K11-linked ubiquitination (GO:0070979)2.63637387
118kidney morphogenesis (GO:0060993)2.63373291
119DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.62732711
120chromatin remodeling at centromere (GO:0031055)2.62705007
121positive regulation of mitochondrial fission (GO:0090141)2.62528571
122* regulation of mRNA splicing, via spliceosome (GO:0048024)2.62291530
123regulation of histone H3-K9 methylation (GO:0051570)2.62281475
124ribosome assembly (GO:0042255)2.61912869
125regulation of RNA export from nucleus (GO:0046831)2.61463349
126termination of RNA polymerase II transcription (GO:0006369)2.61257247
127regulation of nuclear cell cycle DNA replication (GO:0033262)2.60256873
128histone demethylation (GO:0016577)2.59979011
129negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.59720917
130histone exchange (GO:0043486)2.57494481
131negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.57491760
132nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.57117676
133positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.57101290
134positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.57101290
135positive regulation of mitotic sister chromatid separation (GO:1901970)2.57101290
136negative regulation of DNA recombination (GO:0045910)2.56520183
137mitotic spindle checkpoint (GO:0071174)2.55827880
138pyrimidine nucleobase catabolic process (GO:0006208)2.55077403
139* regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.55070782
140histone lysine methylation (GO:0034968)2.54530719
141negative regulation of protein ubiquitination (GO:0031397)2.53902203
142mitochondrial RNA metabolic process (GO:0000959)2.53853783
143negative regulation of DNA-dependent DNA replication (GO:2000104)2.53623829
144positive regulation of gene expression, epigenetic (GO:0045815)2.53415042
145DNA topological change (GO:0006265)2.53007795
146mitotic sister chromatid segregation (GO:0000070)2.51997969
147peptidyl-histidine modification (GO:0018202)2.51056383
148formation of translation preinitiation complex (GO:0001731)2.50409649
149protein-DNA complex disassembly (GO:0032986)2.50301051
150nucleosome disassembly (GO:0006337)2.50301051
151cardiac ventricle formation (GO:0003211)2.50244899
152rRNA methylation (GO:0031167)2.50218078
153sister chromatid cohesion (GO:0007062)2.49924097
154nuclear envelope reassembly (GO:0031468)2.49744168
155mitotic nuclear envelope reassembly (GO:0007084)2.49744168
156chaperone-mediated protein transport (GO:0072321)2.49604380
157oxidative demethylation (GO:0070989)2.48547935
158DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.48218933
159DNA replication checkpoint (GO:0000076)2.48154534
160spindle assembly checkpoint (GO:0071173)2.48118728
161limb bud formation (GO:0060174)2.47446705
162spindle checkpoint (GO:0031577)2.47181516
163mitotic recombination (GO:0006312)2.47075059
164mitotic chromosome condensation (GO:0007076)2.46989056
165spliceosomal tri-snRNP complex assembly (GO:0000244)2.45704544
166regulation of mitotic metaphase/anaphase transition (GO:0030071)2.45324201
167demethylation (GO:0070988)2.44282309
168cardiac chamber formation (GO:0003207)2.43816288
169mRNA export from nucleus (GO:0006406)2.43681888
170negative regulation of stem cell proliferation (GO:2000647)2.43120016
171DNA methylation (GO:0006306)2.42426488
172DNA alkylation (GO:0006305)2.42426488
173protein demethylation (GO:0006482)2.39434018
174protein dealkylation (GO:0008214)2.39434018
175translesion synthesis (GO:0019985)2.39400859
176DNA synthesis involved in DNA repair (GO:0000731)2.38735621
177RNA export from nucleus (GO:0006405)2.38727027
178regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.38698793
179protein K6-linked ubiquitination (GO:0085020)2.38698771
180DNA replication-dependent nucleosome assembly (GO:0006335)2.37731671
181DNA replication-dependent nucleosome organization (GO:0034723)2.37731671
182regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.37411349
183DNA modification (GO:0006304)2.37146548
184telomere maintenance via recombination (GO:0000722)2.35382014

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.59006537
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.96664103
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.71641396
4TP63_19390658_ChIP-ChIP_HaCaT_Human3.63740236
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.51920395
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.43497332
7CREB1_15753290_ChIP-ChIP_HEK293T_Human3.23151454
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.21029435
9SALL1_21062744_ChIP-ChIP_HESCs_Human3.18330024
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.18027058
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.05821938
12* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.64570709
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.63577524
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.57387566
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.41470480
16* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.35041868
17* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.27686088
18GABP_19822575_ChIP-Seq_HepG2_Human2.23961425
19DCP1A_22483619_ChIP-Seq_HELA_Human2.20945010
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.13982477
21FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.09981737
22ELK1_19687146_ChIP-ChIP_HELA_Human2.06518389
23IGF1R_20145208_ChIP-Seq_DFB_Human2.04846805
24EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.03211934
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.99032917
26E2F1_18555785_ChIP-Seq_MESCs_Mouse1.96258487
27ELF1_17652178_ChIP-ChIP_JURKAT_Human1.93356282
28POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.89568196
29ZNF274_21170338_ChIP-Seq_K562_Hela1.89262163
30YY1_21170310_ChIP-Seq_MESCs_Mouse1.87584358
31MYC_19079543_ChIP-ChIP_MESCs_Mouse1.86912264
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.86878827
33E2F1_21310950_ChIP-Seq_MCF-7_Human1.84581087
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.83865412
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.82340251
36* SRF_21415370_ChIP-Seq_HL-1_Mouse1.80984518
37* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.79563963
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.78993216
39PCGF2_27294783_Chip-Seq_ESCs_Mouse1.78064011
40KDM5A_27292631_Chip-Seq_BREAST_Human1.77576569
41* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.77300225
42POU5F1_16153702_ChIP-ChIP_HESCs_Human1.75385196
43HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.73970360
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.72894334
45EST1_17652178_ChIP-ChIP_JURKAT_Human1.72153031
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.68053064
47HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.67313219
48GABP_17652178_ChIP-ChIP_JURKAT_Human1.66724845
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62476656
50CIITA_25753668_ChIP-Seq_RAJI_Human1.62352432
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.61949480
52FOXP3_21729870_ChIP-Seq_TREG_Human1.61172068
53* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59776244
54DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.57899136
55FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.56975200
56SOX2_18555785_ChIP-Seq_MESCs_Mouse1.56188263
57GBX2_23144817_ChIP-Seq_PC3_Human1.55616043
58* VDR_23849224_ChIP-Seq_CD4+_Human1.55354912
59NFE2_27457419_Chip-Seq_LIVER_Mouse1.54995600
60IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.52849812
61HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.51285292
62SUZ12_27294783_Chip-Seq_NPCs_Mouse1.48124003
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.42811013
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.42341639
65* NANOG_16153702_ChIP-ChIP_HESCs_Human1.40598907
66MYC_18940864_ChIP-ChIP_HL60_Human1.40477321
67MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.40025948
68EWS_26573619_Chip-Seq_HEK293_Human1.39494154
69* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.35767334
70* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.32426249
71ZFP57_27257070_Chip-Seq_ESCs_Mouse1.31845844
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.30455961
73THAP11_20581084_ChIP-Seq_MESCs_Mouse1.30097747
74POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28936900
75NANOG_18555785_ChIP-Seq_MESCs_Mouse1.28778856
76CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28281869
77JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.28139020
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.27494119
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27396208
80* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25867888
81NANOG_18555785_Chip-Seq_ESCs_Mouse1.24829807
82SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.24346192
83NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.23553288
84STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.22261134
85E2F1_18555785_Chip-Seq_ESCs_Mouse1.21201062
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19223221
87FUS_26573619_Chip-Seq_HEK293_Human1.19067557
88P53_22387025_ChIP-Seq_ESCs_Mouse1.18574372
89SUZ12_18555785_Chip-Seq_ESCs_Mouse1.18257761
90IRF1_19129219_ChIP-ChIP_H3396_Human1.16260168
91* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.16179722
92GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14611380
93SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.14518245
94STAT3_18555785_Chip-Seq_ESCs_Mouse1.14291972
95ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.13050366
96* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.12332266
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10767438
98NMYC_18555785_Chip-Seq_ESCs_Mouse1.10474974
99NELFA_20434984_ChIP-Seq_ESCs_Mouse1.08648037
100* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.08475894
101ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.08338292
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08272674
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08272674
104MYC_18555785_ChIP-Seq_MESCs_Mouse1.07793088
105ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07408829
106KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06799442
107SOX2_16153702_ChIP-ChIP_HESCs_Human1.05940303
108RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.04107570
109CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.03747760
110SCL_19346495_ChIP-Seq_HPC-7_Human1.03639382
111EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.03390055
112PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02673924
113P300_18555785_Chip-Seq_ESCs_Mouse1.02423618
114OCT4_18555785_Chip-Seq_ESCs_Mouse1.01843007
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00174329
116CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.98860204
117RUNX1_27457419_Chip-Seq_LIVER_Mouse0.98704370
118ZFX_18555785_Chip-Seq_ESCs_Mouse0.98482986
119SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98477537
120CMYC_18555785_Chip-Seq_ESCs_Mouse0.98327801
121* MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97019745
122P300_19829295_ChIP-Seq_ESCs_Human0.96068088
123SOX2_18555785_Chip-Seq_ESCs_Mouse0.96054037
124AR_21909140_ChIP-Seq_LNCAP_Human0.95923175
125GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95376677
126POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92841459
127XRN2_22483619_ChIP-Seq_HELA_Human0.92603091
128TTF2_22483619_ChIP-Seq_HELA_Human0.91821045
129SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.91428390
130ER_23166858_ChIP-Seq_MCF-7_Human0.91412721
131PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90670152
132* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90524414
133* SOX17_20123909_ChIP-Seq_XEN_Mouse0.90493178
134MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89305063
135PU1_27457419_Chip-Seq_LIVER_Mouse0.88582108
136CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.88187620
137SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.88059454
138DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87078124
139* NANOG_21062744_ChIP-ChIP_HESCs_Human0.85682741
140CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.84456884
141ELK1_22589737_ChIP-Seq_MCF10A_Human0.83650406
142SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.76547463
143KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.76135446
144KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.76135446
145KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.76135446
146PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.75735553
147ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.73261217

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.91183692
2MP0008058_abnormal_DNA_repair3.20661390
3MP0003787_abnormal_imprinting2.98665804
4MP0010094_abnormal_chromosome_stability2.81468352
5MP0003693_abnormal_embryo_hatching2.59819472
6MP0000566_synostosis2.55863060
7MP0006292_abnormal_olfactory_placode2.55411037
8MP0009697_abnormal_copulation2.48230414
9MP0003121_genomic_imprinting2.42988896
10MP0008057_abnormal_DNA_replication2.35907837
11MP0003183_abnormal_peptide_metabolism2.34466367
12MP0005645_abnormal_hypothalamus_physiol2.28921079
13MP0008789_abnormal_olfactory_epithelium2.28881200
14MP0000015_abnormal_ear_pigmentation2.24674637
15MP0003111_abnormal_nucleus_morphology2.22979740
16MP0003077_abnormal_cell_cycle2.18115442
17MP0001529_abnormal_vocalization2.14075408
18MP0005174_abnormal_tail_pigmentation2.07721379
19MP0002938_white_spotting1.98783082
20MP0005394_taste/olfaction_phenotype1.93771284
21MP0005499_abnormal_olfactory_system1.93771284
22MP0008007_abnormal_cellular_replicative1.81073698
23MP0003880_abnormal_central_pattern1.80877801
24MP0000537_abnormal_urethra_morphology1.78524308
25MP0002751_abnormal_autonomic_nervous1.71120623
26MP0008877_abnormal_DNA_methylation1.69197920
27MP0002095_abnormal_skin_pigmentation1.63960716
28MP0002638_abnormal_pupillary_reflex1.59886172
29MP0002277_abnormal_respiratory_mucosa1.59546121
30MP0003718_maternal_effect1.59076036
31MP0001346_abnormal_lacrimal_gland1.58313946
32MP0005257_abnormal_intraocular_pressure1.57251292
33MP0004133_heterotaxia1.56759641
34MP0003315_abnormal_perineum_morphology1.55758978
35MP0005646_abnormal_pituitary_gland1.55419078
36MP0003890_abnormal_embryonic-extraembry1.53091100
37MP0008932_abnormal_embryonic_tissue1.52104307
38MP0004134_abnormal_chest_morphology1.50629931
39MP0006072_abnormal_retinal_apoptosis1.48925834
40MP0003763_abnormal_thymus_physiology1.45914614
41MP0000371_diluted_coat_color1.45853567
42MP0001188_hyperpigmentation1.40204552
43MP0002396_abnormal_hematopoietic_system1.39740383
44MP0001293_anophthalmia1.35189841
45MP0003122_maternal_imprinting1.34668979
46MP0002736_abnormal_nociception_after1.33931988
47MP0005408_hypopigmentation1.32195678
48MP0001984_abnormal_olfaction1.32059928
49MP0000631_abnormal_neuroendocrine_gland1.30322024
50MP0006035_abnormal_mitochondrial_morpho1.30149509
51MP0001186_pigmentation_phenotype1.30096160
52MP0002102_abnormal_ear_morphology1.29591166
53MP0002163_abnormal_gland_morphology1.27729737
54MP0002177_abnormal_outer_ear1.26903491
55MP0002075_abnormal_coat/hair_pigmentati1.23630998
56MP0010307_abnormal_tumor_latency1.22523612
57MP0000049_abnormal_middle_ear1.22376761
58MP0003119_abnormal_digestive_system1.21106819
59MP0005253_abnormal_eye_physiology1.20147387
60MP0001730_embryonic_growth_arrest1.17495832
61MP0003937_abnormal_limbs/digits/tail_de1.17364554
62MP0003567_abnormal_fetal_cardiomyocyte1.16013666
63MP0005075_abnormal_melanosome_morpholog1.14091395
64MP0000647_abnormal_sebaceous_gland1.12886436
65MP0000778_abnormal_nervous_system1.10840243
66MP0001286_abnormal_eye_development1.10822330
67MP0005187_abnormal_penis_morphology1.09971662
68MP0002234_abnormal_pharynx_morphology1.09727655
69MP0005171_absent_coat_pigmentation1.09514521
70MP0003786_premature_aging1.08755812
71MP0003935_abnormal_craniofacial_develop1.08536191
72MP0005391_vision/eye_phenotype1.07910959
73MP0009703_decreased_birth_body1.07515327
74MP0009379_abnormal_foot_pigmentation1.06564046
75MP0004957_abnormal_blastocyst_morpholog1.05993943
76MP0002877_abnormal_melanocyte_morpholog1.05563294
77MP0002282_abnormal_trachea_morphology1.04603208
78MP0004808_abnormal_hematopoietic_stem1.02412961
79MP0000372_irregular_coat_pigmentation1.01333995
80MP0010030_abnormal_orbit_morphology1.01036110
81MP0005248_abnormal_Harderian_gland1.00353423
82MP0001929_abnormal_gametogenesis0.99605208
83MP0009672_abnormal_birth_weight0.99441156
84MP0000703_abnormal_thymus_morphology0.98799272
85MP0003938_abnormal_ear_development0.98712588
86MP0003941_abnormal_skin_development0.97903998
87MP0005083_abnormal_biliary_tract0.97724477
88MP0001145_abnormal_male_reproductive0.96912779
89MP0002009_preneoplasia0.96438160
90MP0002184_abnormal_innervation0.96300946
91MP0002254_reproductive_system_inflammat0.96152089
92MP0002697_abnormal_eye_size0.95130562
93MP0002080_prenatal_lethality0.94617524
94MP0001697_abnormal_embryo_size0.94505422
95MP0002398_abnormal_bone_marrow0.93913665
96MP0002210_abnormal_sex_determination0.92322960
97MP0005423_abnormal_somatic_nervous0.92192263
98MP0000653_abnormal_sex_gland0.91526842
99MP0002111_abnormal_tail_morphology0.91156760
100MP0003755_abnormal_palate_morphology0.90725755
101MP0003942_abnormal_urinary_system0.90068713
102MP0008995_early_reproductive_senescence0.90023179
103MP0002092_abnormal_eye_morphology0.89623854
104MP0000350_abnormal_cell_proliferation0.88773147
105MP0003385_abnormal_body_wall0.87983152
106MP0001324_abnormal_eye_pigmentation0.86894728
107MP0002116_abnormal_craniofacial_bone0.86440549
108MP0005389_reproductive_system_phenotype0.86238920
109MP0001119_abnormal_female_reproductive0.85487630
110MP0000358_abnormal_cell_content/0.85033595
111MP0004197_abnormal_fetal_growth/weight/0.84794537
112MP0001764_abnormal_homeostasis0.84792070
113MP0005367_renal/urinary_system_phenotyp0.84261844
114MP0000516_abnormal_urinary_system0.84261844
115MP0003221_abnormal_cardiomyocyte_apopto0.84243907
116MP0004381_abnormal_hair_follicle0.84226831
117MP0003861_abnormal_nervous_system0.84186321
118MP0002109_abnormal_limb_morphology0.83942210
119MP0001672_abnormal_embryogenesis/_devel0.82794038
120MP0005380_embryogenesis_phenotype0.82794038
121MP0002233_abnormal_nose_morphology0.82642768
122MP0002160_abnormal_reproductive_system0.82478930
123MP0003698_abnormal_male_reproductive0.82100512
124MP0000432_abnormal_head_morphology0.80303550
125MP0006276_abnormal_autonomic_nervous0.79574781
126MP0005084_abnormal_gallbladder_morpholo0.79282454
127MP0001835_abnormal_antigen_presentation0.79090512
128MP0000955_abnormal_spinal_cord0.79027847
129MP0003943_abnormal_hepatobiliary_system0.78682262
130MP0003186_abnormal_redox_activity0.77414126
131MP0002084_abnormal_developmental_patter0.76757937
132MP0001879_abnormal_lymphatic_vessel0.76653502
133MP0002653_abnormal_ependyma_morphology0.76410846
134MP0001919_abnormal_reproductive_system0.76097188
135MP0003984_embryonic_growth_retardation0.75488508
136MP0002088_abnormal_embryonic_growth/wei0.75274898
137MP0002085_abnormal_embryonic_tissue0.74924280
138MP0002752_abnormal_somatic_nervous0.74776472
139MP0001800_abnormal_humoral_immune0.74614810
140MP0000313_abnormal_cell_death0.74367133

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.33462263
2Chromsome breakage (HP:0040012)4.02494874
3Abnormality of the fingertips (HP:0001211)3.85542694
4Chronic hepatic failure (HP:0100626)3.61888756
5Cortical dysplasia (HP:0002539)3.34610689
6Ectopic kidney (HP:0000086)3.25786378
7Abnormality of the intervertebral disk (HP:0005108)2.86619329
8Aplasia/Hypoplasia of the uvula (HP:0010293)2.84354852
9Abnormality of chromosome stability (HP:0003220)2.77486432
10Abnormality of DNA repair (HP:0003254)2.72069200
11Meckel diverticulum (HP:0002245)2.68501385
12Abnormality of the nasal septum (HP:0000419)2.63912525
13Abnormality of the preputium (HP:0100587)2.60083902
14Intestinal atresia (HP:0011100)2.58424562
15Abnormality of the ileum (HP:0001549)2.48814801
16Optic nerve coloboma (HP:0000588)2.48704398
17Duplicated collecting system (HP:0000081)2.44808146
18Abnormality of the renal collecting system (HP:0004742)2.43979167
19Acute necrotizing encephalopathy (HP:0006965)2.43459723
20Abnormality of incisor morphology (HP:0011063)2.40633675
21Hepatocellular necrosis (HP:0001404)2.37082519
2211 pairs of ribs (HP:0000878)2.35919545
23Patellar aplasia (HP:0006443)2.34553409
24Microvesicular hepatic steatosis (HP:0001414)2.34167910
25Abnormal protein glycosylation (HP:0012346)2.33358970
26Abnormal glycosylation (HP:0012345)2.33358970
27Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.33358970
28Abnormal protein N-linked glycosylation (HP:0012347)2.33358970
29High anterior hairline (HP:0009890)2.33162665
30Abnormality of the carotid arteries (HP:0005344)2.30993965
31Deep philtrum (HP:0002002)2.30712522
32Bifid tongue (HP:0010297)2.30375359
33Midline defect of the nose (HP:0004122)2.29859721
34Colon cancer (HP:0003003)2.29821412
35Volvulus (HP:0002580)2.28760438
36Increased hepatocellular lipid droplets (HP:0006565)2.28599713
37Reticulocytopenia (HP:0001896)2.28431289
38Aplasia/Hypoplasia involving the musculature (HP:0001460)2.26580427
39Ependymoma (HP:0002888)2.26459248
40Prostate neoplasm (HP:0100787)2.25976722
41Pancreatic fibrosis (HP:0100732)2.25045698
42Mitochondrial inheritance (HP:0001427)2.22590835
43Protruding tongue (HP:0010808)2.22227180
44Abnormal hair whorl (HP:0010721)2.21592516
45Abnormal mitochondria in muscle tissue (HP:0008316)2.21472739
46Optic neuritis (HP:0100653)2.20434305
47Retrobulbar optic neuritis (HP:0100654)2.20434305
48Acute encephalopathy (HP:0006846)2.19855169
49Increased CSF lactate (HP:0002490)2.16480451
50Retinal dysplasia (HP:0007973)2.15861041
51Hemivertebrae (HP:0002937)2.15812077
52Homocystinuria (HP:0002156)2.14885206
53Abnormality of homocysteine metabolism (HP:0010919)2.14885206
54Abnormality of the columella (HP:0009929)2.14832243
55Birth length less than 3rd percentile (HP:0003561)2.13667265
56Abnormality of the incisor (HP:0000676)2.13601672
57Lipid accumulation in hepatocytes (HP:0006561)2.13577127
58Long eyelashes (HP:0000527)2.11855478
59Aplasia/Hypoplasia of the patella (HP:0006498)2.10204283
60Clubbing of toes (HP:0100760)2.10074768
61Congenital primary aphakia (HP:0007707)2.09979255
62Hepatic necrosis (HP:0002605)2.09951894
63Type I transferrin isoform profile (HP:0003642)2.09455002
64Aplasia involving forearm bones (HP:0009822)2.08805164
65Absent forearm bone (HP:0003953)2.08805164
66Medial flaring of the eyebrow (HP:0010747)2.08462697
67Tubulointerstitial nephritis (HP:0001970)2.07843742
68Acute lymphatic leukemia (HP:0006721)2.06241204
69Postnatal microcephaly (HP:0005484)2.04327623
70Abnormality of glycolysis (HP:0004366)2.04005516
71Genital tract atresia (HP:0001827)2.03550365
72Lissencephaly (HP:0001339)2.03412818
73Progressive sensorineural hearing impairment (HP:0000408)2.00750220
74Abnormality of the labia minora (HP:0012880)2.00194290
75Oligodactyly (HP:0012165)1.99829795
76Gait imbalance (HP:0002141)1.98115922
77Vaginal atresia (HP:0000148)1.97945388
78Medulloblastoma (HP:0002885)1.97574963
79Nephrogenic diabetes insipidus (HP:0009806)1.97417338
80Pancreatic cysts (HP:0001737)1.96530410
81Premature graying of hair (HP:0002216)1.96400102
82Anencephaly (HP:0002323)1.92970248
83Myelodysplasia (HP:0002863)1.90352854
84Anophthalmia (HP:0000528)1.90236813
85Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.89821597
86Short 4th metacarpal (HP:0010044)1.89821597
87Cerebral hypomyelination (HP:0006808)1.88690433
88Intellectual disability, moderate (HP:0002342)1.88062683
89Lip pit (HP:0100267)1.88041799
90Increased serum pyruvate (HP:0003542)1.87865934
91Abnormality of the metopic suture (HP:0005556)1.87630381
92Hypoplastic labia majora (HP:0000059)1.87462989
93Oligodactyly (hands) (HP:0001180)1.86950279
94Wrist flexion contracture (HP:0001239)1.86067096
95Dandy-Walker malformation (HP:0001305)1.85996002
96Bone marrow hypocellularity (HP:0005528)1.84944058
97Progressive macrocephaly (HP:0004481)1.83520272
98Duodenal stenosis (HP:0100867)1.83193788
99Small intestinal stenosis (HP:0012848)1.83193788
100Increased serum lactate (HP:0002151)1.82859248
101Facial cleft (HP:0002006)1.82850539
102Horseshoe kidney (HP:0000085)1.82351927
103Hyperglycinemia (HP:0002154)1.82291001
104Aplasia/Hypoplasia of the sternum (HP:0006714)1.81423841
105Drooling (HP:0002307)1.80631048
106Truncal obesity (HP:0001956)1.80140178
107Preaxial hand polydactyly (HP:0001177)1.79620818
108Triphalangeal thumb (HP:0001199)1.79583595
109Glioma (HP:0009733)1.79503365
110Anal atresia (HP:0002023)1.79221418
111Aplasia/Hypoplasia of the tongue (HP:0010295)1.79130806
112Abnormal number of incisors (HP:0011064)1.78693439
113Shoulder girdle muscle weakness (HP:0003547)1.78445498
114Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.78420576
115Anal stenosis (HP:0002025)1.78061479
116Optic nerve hypoplasia (HP:0000609)1.75431327
117Decreased testicular size (HP:0008734)1.75330482
118True hermaphroditism (HP:0010459)1.74372170
1193-Methylglutaconic aciduria (HP:0003535)1.74054031
120Abnormality of the septum pellucidum (HP:0007375)1.74000425
121Abnormality of the anterior horn cell (HP:0006802)1.73894884
122Degeneration of anterior horn cells (HP:0002398)1.73894884
123Papillary thyroid carcinoma (HP:0002895)1.73316184
124Broad foot (HP:0001769)1.72659112
125Trigonocephaly (HP:0000243)1.71359113
126Neonatal hypoglycemia (HP:0001998)1.71130216
127Absent eyebrow (HP:0002223)1.70556288
128Lactic acidosis (HP:0003128)1.70343307
129Absent septum pellucidum (HP:0001331)1.70336217
130Nephroblastoma (Wilms tumor) (HP:0002667)1.69909109
131Abnormality of the phalanges of the hallux (HP:0010057)1.69789608
132Hepatoblastoma (HP:0002884)1.68228899
133Supernumerary spleens (HP:0009799)1.67723766
134Astrocytoma (HP:0009592)1.67529462
135Abnormality of the astrocytes (HP:0100707)1.67529462
136Cutaneous syndactyly (HP:0012725)1.67491920
137Abnormality of the labia (HP:0000058)1.67006557
138Abnormality of the labia majora (HP:0012881)1.66593367
139Thin upper lip vermilion (HP:0000219)1.66482855
140Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.66226649
141Gastrointestinal atresia (HP:0002589)1.65876971
142Hypoplastic pelvis (HP:0008839)1.65866978
143Poor suck (HP:0002033)1.65853608
144Micropenis (HP:0000054)1.65749303
145Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.65429606
146Chorioretinal coloboma (HP:0000567)1.65145478
147Abnormal biliary tract physiology (HP:0012439)1.64910006
148Bile duct proliferation (HP:0001408)1.64910006
149CNS hypomyelination (HP:0003429)1.64627679
150Flat capital femoral epiphysis (HP:0003370)1.64508269
151Spina bifida occulta (HP:0003298)1.63808851
152Prominent nose (HP:0000448)1.62972577
153Abnormality of the parietal bone (HP:0002696)1.62518252
154Prominent metopic ridge (HP:0005487)1.62250378
155Embryonal renal neoplasm (HP:0011794)1.61710073
156Neoplasm of the adrenal cortex (HP:0100641)1.61396791
157Postaxial foot polydactyly (HP:0001830)1.60876837
158Small hand (HP:0200055)1.60722604
159Sloping forehead (HP:0000340)1.60066189
160Duplication of thumb phalanx (HP:0009942)1.59266926
161Abnormal delayed hypersensitivity skin test (HP:0002963)1.57866564
162Absent hand (HP:0004050)1.55955695
163Abnormal lung lobation (HP:0002101)1.54848193
164Sparse lateral eyebrow (HP:0005338)1.53782743
165Renovascular hypertension (HP:0100817)1.53495127
166Cutaneous finger syndactyly (HP:0010554)1.53336434
167Renal hypoplasia (HP:0000089)1.52933467
168Impulsivity (HP:0100710)1.52348471
169Absent radius (HP:0003974)1.51843962
170Absent thumb (HP:0009777)1.51000704
171Short thumb (HP:0009778)1.50049509
172Obsessive-compulsive behavior (HP:0000722)1.49181887
173Keratitis (HP:0000491)1.48003170
174Single transverse palmar crease (HP:0000954)1.47137252
175Abnormality of the duodenum (HP:0002246)1.47132858

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.57977997
2TLK13.66711878
3TSSK63.53909925
4TRIM283.40121739
5ZAK3.39850863
6SIK32.98678278
7BRD42.75565109
8BUB12.66042197
9TXK2.35915065
10MAP4K22.27669985
11MKNK22.26824912
12* SRPK12.26062072
13CDC72.25269327
14WNK32.08628792
15CDK122.00802848
16YES11.95845817
17WEE11.92254724
18ERBB31.88740249
19MKNK11.85969593
20NUAK11.80120681
21EIF2AK11.80055418
22MAP3K41.75591718
23ATR1.71707900
24MAP3K101.65081057
25CHEK21.59111960
26MAPK131.57089781
27TAOK11.52087594
28AKT31.50624265
29PLK41.48150452
30CSNK1G31.47708668
31TESK21.47618486
32NME11.44512709
33STK161.41940820
34CSNK1G11.41587633
35PNCK1.40446437
36CAMK1D1.38958274
37SGK21.36909505
38LATS11.36853464
39EPHA31.36664532
40DYRK31.36337066
41NEK91.36089438
42PBK1.34659793
43MAP3K141.32164852
44VRK11.31462826
45NEK61.28484799
46STK41.27974009
47MAP2K71.27825729
48TNIK1.23449329
49CSNK1G21.21677959
50CDK81.20147462
51PRPF4B1.19170387
52NEK11.17711804
53SIK21.15560661
54IRAK41.13590902
55EPHA41.12860483
56MST41.12660026
57EIF2AK21.10584610
58BRSK11.09062109
59DYRK1A1.08558979
60AURKB1.07688248
61BCKDK1.07106674
62PLK11.06918201
63ATM1.03808256
64INSRR1.01813874
65PASK1.01752540
66STK38L1.01125548
67TAF11.00558259
68DYRK20.97327802
69MELK0.94486202
70PLK30.93112945
71CHEK10.91445102
72MARK10.90182433
73TTK0.89369593
74ACVR1B0.88178126
75CHUK0.87902778
76CDK190.87016811
77FGFR30.83727207
78RPS6KB10.81980006
79CDK40.79170593
80STK30.79096444
81CCNB10.78351432
82SIK10.77868514
83CAMK1G0.75584958
84CDK70.73932088
85CAMK40.72769041
86FGFR20.70771753
87NEK20.70616502
88CDK10.70321926
89EIF2AK30.70254265
90MARK30.68994459
91CASK0.68947892
92PIM10.65918496
93CDK20.65006352
94PAK40.64893351
95PLK20.64755984
96GRK10.63124822
97BMPR1B0.62564624
98LIMK10.62405904
99RPS6KA50.61660990
100IKBKE0.61442108
101MINK10.58794904
102TESK10.57055866
103TAOK20.55114397
104SGK30.54152277
105MAPK140.53153236
106BRSK20.52151743
107CSNK2A10.51939993
108CDK90.50803070
109MARK20.50159566
110AURKA0.49462115
111BCR0.49147806
112CSNK1E0.49026575
113CLK10.48904951
114AKT10.48895167
115PAK30.48691805
116CSNK1A1L0.48325264
117ADRBK20.47595571
118NME20.47447155
119ERBB40.47076668
120PRKDC0.46847368
121CSNK2A20.46082534
122PIM20.46045283
123CDK30.45499505
124TEC0.44867924
125LYN0.44588271
126RPS6KA40.44341756
127DAPK20.44206453
128PRKCI0.43476042
129OBSCN0.42379360
130STK240.41690220
131KSR10.41112756
132CSNK1A10.40811435
133TGFBR10.40740993
134CDK60.40559348
135SGK2230.39973762
136SGK4940.39973762
137FER0.39526822
138GSK3B0.39496428
139EPHB20.39158893
140CDK140.38895410
141IKBKB0.37657405
142PDK20.37235498
143PRKCG0.36630493
144ALK0.36403951
145CDK180.36400338
146DAPK10.36169337
147CSF1R0.35612037
148PRKCE0.35522679
149SGK10.35069041
150NTRK20.33891800
151OXSR10.31435757

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.21803574
2Systemic lupus erythematosus_Homo sapiens_hsa053222.95289989
3Mismatch repair_Homo sapiens_hsa034302.62769647
4Homologous recombination_Homo sapiens_hsa034402.61931750
5Spliceosome_Homo sapiens_hsa030402.60590046
6Non-homologous end-joining_Homo sapiens_hsa034502.54758349
7Cell cycle_Homo sapiens_hsa041102.33092804
8RNA degradation_Homo sapiens_hsa030182.26730374
9DNA replication_Homo sapiens_hsa030302.21434847
10mRNA surveillance pathway_Homo sapiens_hsa030152.13859012
11Steroid biosynthesis_Homo sapiens_hsa001002.07168208
12RNA polymerase_Homo sapiens_hsa030202.03243208
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.01355745
14Nucleotide excision repair_Homo sapiens_hsa034201.97962336
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.95460177
16One carbon pool by folate_Homo sapiens_hsa006701.91763040
17Base excision repair_Homo sapiens_hsa034101.87216458
18Fatty acid elongation_Homo sapiens_hsa000621.80510960
19Oxidative phosphorylation_Homo sapiens_hsa001901.80173217
20Basal transcription factors_Homo sapiens_hsa030221.76724266
21RNA transport_Homo sapiens_hsa030131.74596865
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.71547201
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.70360368
24Parkinsons disease_Homo sapiens_hsa050121.68402466
25Graft-versus-host disease_Homo sapiens_hsa053321.67070065
26Primary immunodeficiency_Homo sapiens_hsa053401.65161779
27Alcoholism_Homo sapiens_hsa050341.57804974
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.54792178
29Herpes simplex infection_Homo sapiens_hsa051681.48967682
30Huntingtons disease_Homo sapiens_hsa050161.48796701
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.47073409
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.45976762
33Allograft rejection_Homo sapiens_hsa053301.44855835
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42367024
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.41579302
36Lysine degradation_Homo sapiens_hsa003101.40131712
37Pyrimidine metabolism_Homo sapiens_hsa002401.39967575
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.39432034
39Sulfur relay system_Homo sapiens_hsa041221.38832530
40Propanoate metabolism_Homo sapiens_hsa006401.38768686
41Biosynthesis of amino acids_Homo sapiens_hsa012301.36698977
42Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.34603038
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.29899772
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27103840
45Viral carcinogenesis_Homo sapiens_hsa052031.27071263
46p53 signaling pathway_Homo sapiens_hsa041151.21602517
47Measles_Homo sapiens_hsa051621.20713747
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.20521291
49MicroRNAs in cancer_Homo sapiens_hsa052061.18399134
50Antigen processing and presentation_Homo sapiens_hsa046121.18072646
51Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.16843221
52Intestinal immune network for IgA production_Homo sapiens_hsa046721.16216595
53Notch signaling pathway_Homo sapiens_hsa043301.15739547
54Autoimmune thyroid disease_Homo sapiens_hsa053201.14449546
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.12352701
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.11668987
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.10626950
58Epstein-Barr virus infection_Homo sapiens_hsa051691.06588016
59Ribosome_Homo sapiens_hsa030101.05662265
60Glutathione metabolism_Homo sapiens_hsa004801.03282276
61Selenocompound metabolism_Homo sapiens_hsa004501.02054913
62Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.01865055
63T cell receptor signaling pathway_Homo sapiens_hsa046601.00870100
64Pyruvate metabolism_Homo sapiens_hsa006200.97990417
65Viral myocarditis_Homo sapiens_hsa054160.93463117
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.92316270
67Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.92153884
68Proteasome_Homo sapiens_hsa030500.91711451
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91402986
70Protein export_Homo sapiens_hsa030600.88699760
71Hedgehog signaling pathway_Homo sapiens_hsa043400.88144183
72Carbon metabolism_Homo sapiens_hsa012000.87862191
73Hematopoietic cell lineage_Homo sapiens_hsa046400.87271691
74Folate biosynthesis_Homo sapiens_hsa007900.86905013
75Influenza A_Homo sapiens_hsa051640.85474938
76Small cell lung cancer_Homo sapiens_hsa052220.84938371
77N-Glycan biosynthesis_Homo sapiens_hsa005100.84392225
78Hepatitis B_Homo sapiens_hsa051610.83746286
79Purine metabolism_Homo sapiens_hsa002300.83636871
80HTLV-I infection_Homo sapiens_hsa051660.82181135
81Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81770102
82Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.79082524
83Colorectal cancer_Homo sapiens_hsa052100.77586983
84Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.77586511
85Basal cell carcinoma_Homo sapiens_hsa052170.74537943
86Maturity onset diabetes of the young_Homo sapiens_hsa049500.73844639
87Hippo signaling pathway_Homo sapiens_hsa043900.72919700
88Collecting duct acid secretion_Homo sapiens_hsa049660.72208714
89Apoptosis_Homo sapiens_hsa042100.70349679
90Phototransduction_Homo sapiens_hsa047440.69827362
91Alzheimers disease_Homo sapiens_hsa050100.69733153
92Butanoate metabolism_Homo sapiens_hsa006500.69426702
93Vibrio cholerae infection_Homo sapiens_hsa051100.67884876
94Prostate cancer_Homo sapiens_hsa052150.67391680
95Asthma_Homo sapiens_hsa053100.67074044
96Metabolic pathways_Homo sapiens_hsa011000.61610679
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60984728
98Chronic myeloid leukemia_Homo sapiens_hsa052200.60751520
99TNF signaling pathway_Homo sapiens_hsa046680.59912586
100Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59346981
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58445367
102Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.58164890
103Toll-like receptor signaling pathway_Homo sapiens_hsa046200.57938268
104Jak-STAT signaling pathway_Homo sapiens_hsa046300.57801801
105Wnt signaling pathway_Homo sapiens_hsa043100.53667845
106Sphingolipid metabolism_Homo sapiens_hsa006000.53406801
107FoxO signaling pathway_Homo sapiens_hsa040680.52956956
108Pentose phosphate pathway_Homo sapiens_hsa000300.52803903
109Type I diabetes mellitus_Homo sapiens_hsa049400.52532494
110Fatty acid metabolism_Homo sapiens_hsa012120.51260593
111Vitamin B6 metabolism_Homo sapiens_hsa007500.51207181
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.50875526
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.49840943
114Endometrial cancer_Homo sapiens_hsa052130.49238520
115Peroxisome_Homo sapiens_hsa041460.49156171
116Melanoma_Homo sapiens_hsa052180.48247140
117Cyanoamino acid metabolism_Homo sapiens_hsa004600.47896851
118Nicotine addiction_Homo sapiens_hsa050330.46639536
119TGF-beta signaling pathway_Homo sapiens_hsa043500.45874102
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45037567
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45036970
122Olfactory transduction_Homo sapiens_hsa047400.44788796
123Pathways in cancer_Homo sapiens_hsa052000.44125672
124Oocyte meiosis_Homo sapiens_hsa041140.41955131
125Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41850521
126Pancreatic cancer_Homo sapiens_hsa052120.41552175
127Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41395112
128Regulation of autophagy_Homo sapiens_hsa041400.40705773
129Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39929693
130Axon guidance_Homo sapiens_hsa043600.39240406
131Type II diabetes mellitus_Homo sapiens_hsa049300.39140261
132Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38852077
133Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.38237598
134Neurotrophin signaling pathway_Homo sapiens_hsa047220.37591145
135SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37118853
136Arginine and proline metabolism_Homo sapiens_hsa003300.35629877
137Adherens junction_Homo sapiens_hsa045200.34627208
138Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34099352
139Legionellosis_Homo sapiens_hsa051340.33681278
140Circadian rhythm_Homo sapiens_hsa047100.32927660
141Tuberculosis_Homo sapiens_hsa051520.32681527
142B cell receptor signaling pathway_Homo sapiens_hsa046620.32479928
143ErbB signaling pathway_Homo sapiens_hsa040120.32269129
144Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.31152477
145Hepatitis C_Homo sapiens_hsa051600.30938077
146Taste transduction_Homo sapiens_hsa047420.29712601
147Osteoclast differentiation_Homo sapiens_hsa043800.29512720
148Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29468334
149Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27673378
150Fructose and mannose metabolism_Homo sapiens_hsa000510.27566177
151Tight junction_Homo sapiens_hsa045300.27155727
152Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.26655700
153beta-Alanine metabolism_Homo sapiens_hsa004100.19483617
154Vitamin digestion and absorption_Homo sapiens_hsa049770.17636358

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