Rank | Gene Set | Z-score |
---|---|---|
1 | DNA deamination (GO:0045006) | 6.14094388 |
2 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.84322917 |
3 | formation of translation preinitiation complex (GO:0001731) | 4.52641142 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 4.48085891 |
5 | Golgi transport vesicle coating (GO:0048200) | 4.48085891 |
6 | protein maturation by protein folding (GO:0022417) | 4.40449615 |
7 | maturation of SSU-rRNA (GO:0030490) | 4.34512268 |
8 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 4.29180637 |
9 | viral transcription (GO:0019083) | 4.20768618 |
10 | ribosomal small subunit assembly (GO:0000028) | 4.14955605 |
11 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.10536435 |
12 | translational termination (GO:0006415) | 4.08946070 |
13 | nucleobase biosynthetic process (GO:0046112) | 4.07767997 |
14 | ribosome assembly (GO:0042255) | 4.03684281 |
15 | purine nucleobase biosynthetic process (GO:0009113) | 3.97005853 |
16 | nuclear envelope reassembly (GO:0031468) | 3.96885268 |
17 | mitotic nuclear envelope reassembly (GO:0007084) | 3.96885268 |
18 | ribosome biogenesis (GO:0042254) | 3.93915488 |
19 | translational initiation (GO:0006413) | 3.90521163 |
20 | proline biosynthetic process (GO:0006561) | 3.88908154 |
21 | DNA strand elongation (GO:0022616) | 3.82365839 |
22 | translational elongation (GO:0006414) | 3.81700837 |
23 | GDP-mannose metabolic process (GO:0019673) | 3.74544691 |
24 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.74219150 |
25 | DNA unwinding involved in DNA replication (GO:0006268) | 3.73591180 |
26 | ribosomal small subunit biogenesis (GO:0042274) | 3.72193533 |
27 | folic acid metabolic process (GO:0046655) | 3.71016304 |
28 | pentose-phosphate shunt (GO:0006098) | 3.71011391 |
29 | proteasome assembly (GO:0043248) | 3.69152876 |
30 | DNA replication initiation (GO:0006270) | 3.63471254 |
31 | ribosomal large subunit biogenesis (GO:0042273) | 3.62238910 |
32 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.49524059 |
33 | protein retention in ER lumen (GO:0006621) | 3.49190149 |
34 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.47747772 |
35 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.46391689 |
36 | DNA replication checkpoint (GO:0000076) | 3.44543888 |
37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.42964132 |
38 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.39410618 |
39 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.35487818 |
40 | barbed-end actin filament capping (GO:0051016) | 3.35136542 |
41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.33478259 |
42 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.32784096 |
43 | viral life cycle (GO:0019058) | 3.31342024 |
44 | NIK/NF-kappaB signaling (GO:0038061) | 3.30282603 |
45 | glucose catabolic process (GO:0006007) | 3.29492324 |
46 | rRNA processing (GO:0006364) | 3.29012268 |
47 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.28790592 |
48 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.28004190 |
49 | negative regulation of cell size (GO:0045792) | 3.27416295 |
50 | protein targeting to ER (GO:0045047) | 3.27062375 |
51 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.26638197 |
52 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.25552378 |
53 | mitotic nuclear envelope disassembly (GO:0007077) | 3.25106981 |
54 | cotranslational protein targeting to membrane (GO:0006613) | 3.24265323 |
55 | spliceosomal snRNP assembly (GO:0000387) | 3.23371540 |
56 | cellular protein complex disassembly (GO:0043624) | 3.21398683 |
57 | IMP biosynthetic process (GO:0006188) | 3.20981373 |
58 | pentose metabolic process (GO:0019321) | 3.20934632 |
59 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 3.20322789 |
60 | protein localization to kinetochore (GO:0034501) | 3.19064884 |
61 | rRNA metabolic process (GO:0016072) | 3.17162846 |
62 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.15305046 |
63 | negative regulation of ligase activity (GO:0051352) | 3.14290913 |
64 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.14290913 |
65 | apoptotic process involved in morphogenesis (GO:0060561) | 3.13450972 |
66 | mitotic metaphase plate congression (GO:0007080) | 3.13286052 |
67 | histone arginine methylation (GO:0034969) | 3.12808325 |
68 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.12446216 |
69 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.12446216 |
70 | UV protection (GO:0009650) | 3.11882939 |
71 | NADPH regeneration (GO:0006740) | 3.11841428 |
72 | protein localization to endoplasmic reticulum (GO:0070972) | 3.11302501 |
73 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.09298690 |
74 | mitotic chromosome condensation (GO:0007076) | 3.08722803 |
75 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.08195547 |
76 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.08041377 |
77 | peptidyl-arginine N-methylation (GO:0035246) | 3.07062820 |
78 | peptidyl-arginine methylation (GO:0018216) | 3.07062820 |
79 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.06858406 |
80 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 3.02390113 |
81 | membrane disassembly (GO:0030397) | 3.01358338 |
82 | nuclear envelope disassembly (GO:0051081) | 3.01358338 |
83 | protein complex disassembly (GO:0043241) | 3.00551705 |
84 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.00028352 |
85 | negative regulation of translational initiation (GO:0045947) | 2.99161462 |
86 | pinocytosis (GO:0006907) | 2.97703254 |
87 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.93727266 |
88 | negative regulation of B cell apoptotic process (GO:0002903) | 2.92802712 |
89 | protein localization to chromosome, centromeric region (GO:0071459) | 2.91194989 |
90 | pseudouridine synthesis (GO:0001522) | 2.90072118 |
91 | telomere maintenance via recombination (GO:0000722) | 2.89863223 |
92 | translation (GO:0006412) | 2.89319066 |
93 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.85805710 |
94 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.84584177 |
95 | macromolecular complex disassembly (GO:0032984) | 2.83329166 |
96 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.83017839 |
97 | endoplasmic reticulum calcium ion homeostasis (GO:0032469) | 2.79899135 |
98 | IMP metabolic process (GO:0046040) | 2.79487522 |
99 | positive regulation of ligase activity (GO:0051351) | 2.79132659 |
100 | telomere maintenance via telomere lengthening (GO:0010833) | 2.78825972 |
101 | regulation of translation in response to stress (GO:0043555) | 2.76526692 |
102 | rRNA modification (GO:0000154) | 2.76406027 |
103 | protein localization to endosome (GO:0036010) | 2.74059597 |
104 | ncRNA 3-end processing (GO:0043628) | 2.73860032 |
105 | regulation of translational termination (GO:0006449) | 2.72439356 |
106 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.72157549 |
107 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.71723912 |
108 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.71444317 |
109 | regulation of spindle organization (GO:0090224) | 2.70548899 |
110 | pyrimidine-containing compound salvage (GO:0008655) | 2.69504552 |
111 | pyrimidine nucleoside salvage (GO:0043097) | 2.69504552 |
112 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.68882083 |
113 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.68512109 |
114 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.68512109 |
115 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.68512109 |
116 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 2.68312425 |
117 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.68213553 |
118 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.68213553 |
119 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.68047684 |
120 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.67366313 |
121 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.67366313 |
122 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.67048674 |
123 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.64979536 |
124 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.64979536 |
125 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.64885595 |
126 | regulation of superoxide anion generation (GO:0032928) | 2.64859188 |
127 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.64697793 |
128 | nucleotide salvage (GO:0043173) | 2.63248566 |
129 | mitotic recombination (GO:0006312) | 2.63041143 |
130 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.62838384 |
131 | negative regulation of chromosome segregation (GO:0051985) | 2.62329389 |
132 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.62011728 |
133 | nuclear envelope organization (GO:0006998) | 2.61549066 |
134 | cell cycle G1/S phase transition (GO:0044843) | 2.61432943 |
135 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.61432943 |
136 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.60801729 |
137 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.60609354 |
138 | termination of RNA polymerase III transcription (GO:0006386) | 2.60609354 |
139 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.59782631 |
140 | protein insertion into membrane (GO:0051205) | 2.59732944 |
141 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 2.59162363 |
142 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.58747107 |
143 | cellular component biogenesis (GO:0044085) | 2.57828637 |
144 | mitotic spindle assembly checkpoint (GO:0007094) | 2.55642048 |
145 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.55275517 |
146 | mRNA splicing, via spliceosome (GO:0000398) | 2.55275517 |
147 | RNA splicing, via transesterification reactions (GO:0000375) | 2.54708898 |
148 | RNA catabolic process (GO:0006401) | 2.53958241 |
149 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.53943748 |
150 | mitochondrial fusion (GO:0008053) | 2.52170708 |
151 | heterochromatin organization (GO:0070828) | 2.52111292 |
152 | modulation by symbiont of host cellular process (GO:0044068) | 2.51461191 |
153 | virion assembly (GO:0019068) | 2.50592549 |
154 | regulation of early endosome to late endosome transport (GO:2000641) | 2.49705294 |
155 | modulation by virus of host process (GO:0019054) | 2.48871289 |
156 | establishment of viral latency (GO:0019043) | 2.47861484 |
157 | amyloid precursor protein catabolic process (GO:0042987) | 2.47395503 |
158 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.47321156 |
159 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.46777803 |
160 | rRNA transcription (GO:0009303) | 2.43597281 |
161 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.42618086 |
162 | regulation of mitochondrial translation (GO:0070129) | 2.41730315 |
163 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.41605729 |
164 | NADH metabolic process (GO:0006734) | 2.41208140 |
165 | establishment of integrated proviral latency (GO:0075713) | 2.39454316 |
166 | negative regulation of necroptotic process (GO:0060546) | 2.38823418 |
167 | proline metabolic process (GO:0006560) | 2.38348085 |
168 | glucose 6-phosphate metabolic process (GO:0051156) | 2.36003061 |
169 | UTP biosynthetic process (GO:0006228) | 2.35701521 |
170 | regulation of translational fidelity (GO:0006450) | 2.33810598 |
171 | mature B cell differentiation involved in immune response (GO:0002313) | 2.33459876 |
172 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.32563880 |
173 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.31830302 |
174 | regulation of mitochondrial membrane potential (GO:0051881) | 2.30571958 |
175 | activation of MAPKKK activity (GO:0000185) | 2.30442920 |
176 | regulation of defense response to virus by virus (GO:0050690) | 2.29578598 |
177 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.29021928 |
178 | activation of Rac GTPase activity (GO:0032863) | 2.26641969 |
179 | response to peptidoglycan (GO:0032494) | 2.26560438 |
180 | viral mRNA export from host cell nucleus (GO:0046784) | 2.26082144 |
181 | viral protein processing (GO:0019082) | 2.24002312 |
182 | negative regulation of mRNA processing (GO:0050686) | 2.23686833 |
183 | regulation of necrotic cell death (GO:0010939) | 2.23106351 |
184 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.22603586 |
185 | negative regulation of viral release from host cell (GO:1902187) | 2.19488332 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.07510706 |
2 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.89542201 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.54972194 |
4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.63930639 |
5 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.52727350 |
6 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.52380623 |
7 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.52276593 |
8 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.47274563 |
9 | MYC_22102868_ChIP-Seq_BL_Human | 2.34706946 |
10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.28281079 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.27781265 |
12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.19661459 |
13 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.19204221 |
14 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.16490648 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.15752014 |
16 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.07845046 |
17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.07175471 |
18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.06760029 |
19 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.99121907 |
20 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.92717989 |
21 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.89304428 |
22 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.86464963 |
23 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.84372348 |
24 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.83631079 |
25 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.79501703 |
26 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.78650907 |
27 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.77407895 |
28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74815567 |
29 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.74484669 |
30 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.73685286 |
31 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69259425 |
32 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.69143575 |
33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.67554328 |
34 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.64453948 |
35 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.62981905 |
36 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.62759365 |
37 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.59705235 |
38 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.57829109 |
39 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.54126711 |
40 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.52055470 |
41 | P68_20966046_ChIP-Seq_HELA_Human | 1.51186395 |
42 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.50974158 |
43 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.49518349 |
44 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.48785017 |
45 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.48748484 |
46 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.48586436 |
47 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.47553479 |
48 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.47404913 |
49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.45242283 |
50 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.44995198 |
51 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.44520818 |
52 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.43260178 |
53 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.41676852 |
54 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.40567241 |
55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39548912 |
56 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.39162527 |
57 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.38889244 |
58 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.38441742 |
59 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.38241976 |
60 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.37796626 |
61 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34892680 |
62 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.33204458 |
63 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.32337421 |
64 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.31066424 |
65 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31038891 |
66 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.30231091 |
67 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.28594510 |
68 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.27033415 |
69 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.25816927 |
70 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.24057541 |
71 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.23562265 |
72 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.22480856 |
73 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.21077031 |
74 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.16678499 |
75 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.16578633 |
76 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.16447762 |
77 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.16286312 |
78 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.16189897 |
79 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.15067636 |
80 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.12886384 |
81 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.12374983 |
82 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.12082905 |
83 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.11674204 |
84 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.11465036 |
85 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.10720259 |
86 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.10525932 |
87 | MAF_26560356_Chip-Seq_TH1_Human | 1.10202902 |
88 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.09840693 |
89 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09818916 |
90 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.09777358 |
91 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.08727916 |
92 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.08153692 |
93 | MAF_26560356_Chip-Seq_TH2_Human | 1.07705784 |
94 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.06918320 |
95 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.06572256 |
96 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.06214193 |
97 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.06069960 |
98 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.05527492 |
99 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03795525 |
100 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.03752115 |
101 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.03683699 |
102 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.03654930 |
103 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.03584071 |
104 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.03206561 |
105 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.03117587 |
106 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03049320 |
107 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.02228217 |
108 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.01858169 |
109 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01704275 |
110 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.01518083 |
111 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.01313526 |
112 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.01301680 |
113 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01281073 |
114 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.00792807 |
115 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.00075345 |
116 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.00001615 |
117 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.99909607 |
118 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.99768067 |
119 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.99495996 |
120 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.99317637 |
121 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.99200127 |
122 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.98855435 |
123 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.98578616 |
124 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98372208 |
125 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.97806165 |
126 | * ATF3_27146783_Chip-Seq_COLON_Human | 0.96928014 |
127 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.96842560 |
128 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.95634346 |
129 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.95485482 |
130 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.95052916 |
131 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.94961077 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.16663568 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.74617828 |
3 | MP0003111_abnormal_nucleus_morphology | 3.56329748 |
4 | MP0005058_abnormal_lysosome_morphology | 3.42015615 |
5 | MP0005451_abnormal_body_composition | 3.31892313 |
6 | MP0003077_abnormal_cell_cycle | 2.98488358 |
7 | MP0010094_abnormal_chromosome_stability | 2.75403363 |
8 | MP0002877_abnormal_melanocyte_morpholog | 2.75177202 |
9 | MP0010352_gastrointestinal_tract_polyps | 2.47363391 |
10 | MP0004185_abnormal_adipocyte_glucose | 2.43024462 |
11 | MP0002396_abnormal_hematopoietic_system | 2.42089810 |
12 | MP0009333_abnormal_splenocyte_physiolog | 2.22382684 |
13 | MP0009840_abnormal_foam_cell | 2.18897699 |
14 | MP0001730_embryonic_growth_arrest | 2.12920278 |
15 | MP0008007_abnormal_cellular_replicative | 2.07682831 |
16 | MP0008932_abnormal_embryonic_tissue | 2.02057345 |
17 | MP0000685_abnormal_immune_system | 2.01457248 |
18 | MP0003315_abnormal_perineum_morphology | 2.00299922 |
19 | MP0003763_abnormal_thymus_physiology | 1.97817630 |
20 | MP0000490_abnormal_crypts_of | 1.97798978 |
21 | MP0008058_abnormal_DNA_repair | 1.97350863 |
22 | MP0004858_abnormal_nervous_system | 1.87302143 |
23 | MP0008057_abnormal_DNA_replication | 1.86939194 |
24 | MP0000678_abnormal_parathyroid_gland | 1.86401250 |
25 | MP0005623_abnormal_meninges_morphology | 1.84053023 |
26 | MP0000350_abnormal_cell_proliferation | 1.77768984 |
27 | MP0001545_abnormal_hematopoietic_system | 1.67818290 |
28 | MP0005397_hematopoietic_system_phenotyp | 1.67818290 |
29 | MP0003453_abnormal_keratinocyte_physiol | 1.53573278 |
30 | MP0004233_abnormal_muscle_weight | 1.50273795 |
31 | MP0002398_abnormal_bone_marrow | 1.49397286 |
32 | MP0003786_premature_aging | 1.49239097 |
33 | MP0003123_paternal_imprinting | 1.47758104 |
34 | MP0009278_abnormal_bone_marrow | 1.47200551 |
35 | MP0002080_prenatal_lethality | 1.45870108 |
36 | MP0010234_abnormal_vibrissa_follicle | 1.45482531 |
37 | MP0001672_abnormal_embryogenesis/_devel | 1.44578820 |
38 | MP0005380_embryogenesis_phenotype | 1.44578820 |
39 | MP0008438_abnormal_cutaneous_collagen | 1.44438061 |
40 | MP0003436_decreased_susceptibility_to | 1.44320758 |
41 | MP0002249_abnormal_larynx_morphology | 1.44130841 |
42 | MP0002722_abnormal_immune_system | 1.43483996 |
43 | MP0001697_abnormal_embryo_size | 1.43324368 |
44 | MP0003718_maternal_effect | 1.43247516 |
45 | MP0002019_abnormal_tumor_incidence | 1.43240800 |
46 | MP0000313_abnormal_cell_death | 1.42913310 |
47 | MP0005666_abnormal_adipose_tissue | 1.42650192 |
48 | MP0000537_abnormal_urethra_morphology | 1.42317575 |
49 | MP0002796_impaired_skin_barrier | 1.41378446 |
50 | MP0000003_abnormal_adipose_tissue | 1.41230037 |
51 | MP0002653_abnormal_ependyma_morphology | 1.39892828 |
52 | MP0000689_abnormal_spleen_morphology | 1.39246452 |
53 | MP0004808_abnormal_hematopoietic_stem | 1.37323958 |
54 | MP0010307_abnormal_tumor_latency | 1.34374757 |
55 | MP0000703_abnormal_thymus_morphology | 1.33765730 |
56 | MP0005375_adipose_tissue_phenotype | 1.33044438 |
57 | MP0003984_embryonic_growth_retardation | 1.32078673 |
58 | MP0002088_abnormal_embryonic_growth/wei | 1.30821560 |
59 | MP0003806_abnormal_nucleotide_metabolis | 1.30177265 |
60 | MP0005076_abnormal_cell_differentiation | 1.28735107 |
61 | MP0002429_abnormal_blood_cell | 1.26231692 |
62 | MP0003075_altered_response_to | 1.24739233 |
63 | MP0000681_abnormal_thyroid_gland | 1.24517834 |
64 | MP0003705_abnormal_hypodermis_morpholog | 1.23657076 |
65 | MP0001835_abnormal_antigen_presentation | 1.21751341 |
66 | MP0000716_abnormal_immune_system | 1.20915394 |
67 | MP0005377_hearing/vestibular/ear_phenot | 1.20511610 |
68 | MP0003878_abnormal_ear_physiology | 1.20511610 |
69 | MP0000343_altered_response_to | 1.20218804 |
70 | MP0005023_abnormal_wound_healing | 1.19573682 |
71 | MP0002085_abnormal_embryonic_tissue | 1.18391349 |
72 | MP0001800_abnormal_humoral_immune | 1.15517580 |
73 | MP0010030_abnormal_orbit_morphology | 1.15429358 |
74 | MP0002405_respiratory_system_inflammati | 1.15422721 |
75 | MP0000733_abnormal_muscle_development | 1.15322679 |
76 | MP0008260_abnormal_autophagy | 1.14978937 |
77 | MP0002132_abnormal_respiratory_system | 1.14931092 |
78 | MP0002086_abnormal_extraembryonic_tissu | 1.14536673 |
79 | MP0000858_altered_metastatic_potential | 1.11312578 |
80 | MP0001819_abnormal_immune_cell | 1.10056974 |
81 | MP0002452_abnormal_antigen_presenting | 1.09766002 |
82 | MP0001849_ear_inflammation | 1.09679049 |
83 | MP0002420_abnormal_adaptive_immunity | 1.09529661 |
84 | MP0003303_peritoneal_inflammation | 1.08907177 |
85 | MP0002723_abnormal_immune_serum | 1.06949708 |
86 | MP0001853_heart_inflammation | 1.06852179 |
87 | MP0000751_myopathy | 1.05525871 |
88 | MP0002084_abnormal_developmental_patter | 1.05360107 |
89 | MP0003191_abnormal_cellular_cholesterol | 1.04801679 |
90 | MP0000358_abnormal_cell_content/ | 1.04636250 |
91 | MP0004510_myositis | 1.03722377 |
92 | MP0005671_abnormal_response_to | 1.03668404 |
93 | MP0005670_abnormal_white_adipose | 1.01524013 |
94 | MP0001661_extended_life_span | 1.00536541 |
95 | MP0000747_muscle_weakness | 0.99891839 |
96 | MP0005330_cardiomyopathy | 0.99383002 |
97 | MP0005025_abnormal_response_to | 0.99132089 |
98 | MP0003300_gastrointestinal_ulcer | 0.98933151 |
99 | MP0001873_stomach_inflammation | 0.98337409 |
100 | MP0009785_altered_susceptibility_to | 0.98328649 |
101 | MP0003329_amyloid_beta_deposits | 0.98300610 |
102 | MP0005075_abnormal_melanosome_morpholog | 0.98126509 |
103 | MP0009053_abnormal_anal_canal | 0.96641262 |
104 | MP0005000_abnormal_immune_tolerance | 0.96176970 |
105 | MP0003566_abnormal_cell_adhesion | 0.96159815 |
106 | MP0005257_abnormal_intraocular_pressure | 0.95806979 |
107 | MP0004197_abnormal_fetal_growth/weight/ | 0.95694997 |
108 | MP0003279_aneurysm | 0.95564518 |
109 | MP0004947_skin_inflammation | 0.95298425 |
110 | MP0003119_abnormal_digestive_system | 0.94948354 |
111 | MP0003221_abnormal_cardiomyocyte_apopto | 0.94704238 |
112 | MP0010155_abnormal_intestine_physiology | 0.94622239 |
113 | MP0000759_abnormal_skeletal_muscle | 0.93791139 |
114 | MP0002160_abnormal_reproductive_system | 0.93335086 |
115 | MP0000477_abnormal_intestine_morphology | 0.92093443 |
116 | MP0004272_abnormal_basement_membrane | 0.92025644 |
117 | MP0003866_abnormal_defecation | 0.90870335 |
118 | MP0001346_abnormal_lacrimal_gland | 0.90707279 |
119 | MP0003172_abnormal_lysosome_physiology | 0.90483839 |
120 | MP0001533_abnormal_skeleton_physiology | 0.90128901 |
121 | MP0000465_gastrointestinal_hemorrhage | 0.89937956 |
122 | MP0009672_abnormal_birth_weight | 0.89114910 |
123 | MP0002148_abnormal_hypersensitivity_rea | 0.88940619 |
124 | MP0000750_abnormal_muscle_regeneration | 0.86727965 |
125 | MP0002419_abnormal_innate_immunity | 0.86545167 |
126 | MP0002060_abnormal_skin_morphology | 0.86196417 |
127 | MP0003186_abnormal_redox_activity | 0.83654507 |
128 | MP0001727_abnormal_embryo_implantation | 0.83331795 |
129 | MP0003091_abnormal_cell_migration | 0.81424256 |
130 | MP0001542_abnormal_bone_strength | 0.80088533 |
131 | MP0006036_abnormal_mitochondrial_physio | 0.79854323 |
132 | MP0001216_abnormal_epidermal_layer | 0.79730252 |
133 | MP0005621_abnormal_cell_physiology | 0.79344999 |
134 | MP0008877_abnormal_DNA_methylation | 0.78741834 |
135 | MP0009379_abnormal_foot_pigmentation | 0.78160362 |
136 | MP0009931_abnormal_skin_appearance | 0.77396615 |
137 | MP0005384_cellular_phenotype | 0.76384141 |
138 | MP0005390_skeleton_phenotype | 0.76050735 |
139 | MP0002166_altered_tumor_susceptibility | 0.74453472 |
140 | MP0001845_abnormal_inflammatory_respons | 0.74101580 |
141 | MP0001790_abnormal_immune_system | 0.74037009 |
142 | MP0005387_immune_system_phenotype | 0.74037009 |
143 | MP0003567_abnormal_fetal_cardiomyocyte | 0.71632737 |
144 | MP0000598_abnormal_liver_morphology | 0.70912770 |
145 | MP0005501_abnormal_skin_physiology | 0.69922223 |
146 | MP0001145_abnormal_male_reproductive | 0.69588986 |
147 | MP0005464_abnormal_platelet_physiology | 0.65337592 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.04648634 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 3.97240659 |
3 | Carpal bone hypoplasia (HP:0001498) | 3.91698501 |
4 | Breast hypoplasia (HP:0003187) | 3.65482920 |
5 | Ragged-red muscle fibers (HP:0003200) | 3.47944437 |
6 | Oral leukoplakia (HP:0002745) | 3.42836764 |
7 | Achilles tendon contracture (HP:0001771) | 3.41139423 |
8 | Cerebral hypomyelination (HP:0006808) | 3.36633638 |
9 | Multiple enchondromatosis (HP:0005701) | 3.35419714 |
10 | Reticulocytopenia (HP:0001896) | 3.34272243 |
11 | Birth length less than 3rd percentile (HP:0003561) | 3.32743042 |
12 | Distal lower limb amyotrophy (HP:0008944) | 3.21253316 |
13 | Progressive muscle weakness (HP:0003323) | 3.17272253 |
14 | Rough bone trabeculation (HP:0100670) | 3.12609016 |
15 | Microretrognathia (HP:0000308) | 3.07433464 |
16 | Trismus (HP:0000211) | 3.07019344 |
17 | Hyperacusis (HP:0010780) | 3.06486664 |
18 | Premature ovarian failure (HP:0008209) | 3.04875550 |
19 | Abnormality of the anterior horn cell (HP:0006802) | 3.02800220 |
20 | Degeneration of anterior horn cells (HP:0002398) | 3.02800220 |
21 | Abnormality of the Achilles tendon (HP:0005109) | 3.00004688 |
22 | Abnormality of glycolipid metabolism (HP:0010969) | 2.98735281 |
23 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.98735281 |
24 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.98735281 |
25 | Broad distal phalanx of finger (HP:0009836) | 2.93969699 |
26 | Selective tooth agenesis (HP:0001592) | 2.92477590 |
27 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.90423477 |
28 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.87067022 |
29 | Patellar aplasia (HP:0006443) | 2.83982002 |
30 | Distal lower limb muscle weakness (HP:0009053) | 2.82391506 |
31 | Macrocytic anemia (HP:0001972) | 2.81850591 |
32 | Cholecystitis (HP:0001082) | 2.81233629 |
33 | Abnormal gallbladder physiology (HP:0012438) | 2.81233629 |
34 | Premature rupture of membranes (HP:0001788) | 2.80184097 |
35 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.77695578 |
36 | Polycythemia (HP:0001901) | 2.69326034 |
37 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.68783212 |
38 | Hypertensive crisis (HP:0100735) | 2.63735585 |
39 | Tongue fasciculations (HP:0001308) | 2.62170944 |
40 | Pustule (HP:0200039) | 2.58230939 |
41 | Petechiae (HP:0000967) | 2.58047088 |
42 | Pallor (HP:0000980) | 2.55803528 |
43 | Thrombocytosis (HP:0001894) | 2.54568824 |
44 | Increased connective tissue (HP:0009025) | 2.54276616 |
45 | Secondary amenorrhea (HP:0000869) | 2.53198610 |
46 | Muscle fibrillation (HP:0010546) | 2.50753918 |
47 | Neoplasm of the pancreas (HP:0002894) | 2.47397073 |
48 | Ulnar bowing (HP:0003031) | 2.45937558 |
49 | IgM deficiency (HP:0002850) | 2.44032792 |
50 | Aplastic anemia (HP:0001915) | 2.41738580 |
51 | Cellulitis (HP:0100658) | 2.34430772 |
52 | Chronic otitis media (HP:0000389) | 2.34347833 |
53 | Breech presentation (HP:0001623) | 2.33738845 |
54 | Personality changes (HP:0000751) | 2.28188237 |
55 | Abnormality of the nasal mucosa (HP:0000433) | 2.28069177 |
56 | Upper limb amyotrophy (HP:0009129) | 2.27999567 |
57 | Distal upper limb amyotrophy (HP:0007149) | 2.27999567 |
58 | Increased cerebral lipofuscin (HP:0011813) | 2.26768678 |
59 | Short nail (HP:0001799) | 2.26148740 |
60 | Abnormality of T cell physiology (HP:0011840) | 2.26077912 |
61 | Axonal loss (HP:0003447) | 2.25298379 |
62 | Nasal polyposis (HP:0100582) | 2.24835105 |
63 | Overlapping toe (HP:0001845) | 2.22586309 |
64 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.22182382 |
65 | Stridor (HP:0010307) | 2.19961224 |
66 | Myopathic facies (HP:0002058) | 2.19589973 |
67 | Generalized amyotrophy (HP:0003700) | 2.19110843 |
68 | Entropion (HP:0000621) | 2.15762295 |
69 | Testicular atrophy (HP:0000029) | 2.14958330 |
70 | Prolonged neonatal jaundice (HP:0006579) | 2.14470380 |
71 | Facial hemangioma (HP:0000329) | 2.13281183 |
72 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.11094864 |
73 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.11094864 |
74 | Single umbilical artery (HP:0001195) | 2.11094864 |
75 | Long palpebral fissure (HP:0000637) | 2.09177614 |
76 | Abnormal trabecular bone morphology (HP:0100671) | 2.08950015 |
77 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.06886808 |
78 | Microvesicular hepatic steatosis (HP:0001414) | 2.05752613 |
79 | Hepatosplenomegaly (HP:0001433) | 2.02714071 |
80 | Nonimmune hydrops fetalis (HP:0001790) | 2.01991918 |
81 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.00045184 |
82 | Abnormality of T cells (HP:0002843) | 1.99006452 |
83 | Dysostosis multiplex (HP:0000943) | 1.97584648 |
84 | Chronic obstructive pulmonary disease (HP:0006510) | 1.96870491 |
85 | Obstructive lung disease (HP:0006536) | 1.96870491 |
86 | Recurrent bronchitis (HP:0002837) | 1.96375601 |
87 | Abnormality of the umbilical cord (HP:0010881) | 1.96328234 |
88 | Insomnia (HP:0100785) | 1.95084328 |
89 | Poor head control (HP:0002421) | 1.94526491 |
90 | CNS hypomyelination (HP:0003429) | 1.94279474 |
91 | Upper motor neuron abnormality (HP:0002127) | 1.93954706 |
92 | Absent thumb (HP:0009777) | 1.93914943 |
93 | Loss of speech (HP:0002371) | 1.91452049 |
94 | Hyperparathyroidism (HP:0000843) | 1.91449581 |
95 | Lower limb amyotrophy (HP:0007210) | 1.90815846 |
96 | Elbow flexion contracture (HP:0002987) | 1.90165635 |
97 | Basal cell carcinoma (HP:0002671) | 1.89239887 |
98 | Cleft eyelid (HP:0000625) | 1.88933053 |
99 | Pelvic girdle muscle weakness (HP:0003749) | 1.88154585 |
100 | Truncus arteriosus (HP:0001660) | 1.87887723 |
101 | Abnormal neuron morphology (HP:0012757) | 1.87453943 |
102 | Abnormality of the motor neurons (HP:0002450) | 1.87453943 |
103 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.86266872 |
104 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.86266872 |
105 | Slender long bone (HP:0003100) | 1.85907597 |
106 | Cellular immunodeficiency (HP:0005374) | 1.85630659 |
107 | Sparse eyelashes (HP:0000653) | 1.85325180 |
108 | Poikiloderma (HP:0001029) | 1.84961329 |
109 | Colon cancer (HP:0003003) | 1.84928748 |
110 | Spinal rigidity (HP:0003306) | 1.84416864 |
111 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.84054245 |
112 | Premature graying of hair (HP:0002216) | 1.83750797 |
113 | Protrusio acetabuli (HP:0003179) | 1.81504556 |
114 | Absent radius (HP:0003974) | 1.80564582 |
115 | Abnormality of the tricuspid valve (HP:0001702) | 1.80480658 |
116 | Calcaneovalgus deformity (HP:0001848) | 1.79352267 |
117 | Hypokinesia (HP:0002375) | 1.78971834 |
118 | Increased muscle lipid content (HP:0009058) | 1.78691030 |
119 | Broad face (HP:0000283) | 1.78088421 |
120 | Gastrointestinal dysmotility (HP:0002579) | 1.76974954 |
121 | Hypertriglyceridemia (HP:0002155) | 1.76442987 |
122 | Prominent nose (HP:0000448) | 1.76437540 |
123 | Reticulocytosis (HP:0001923) | 1.76051940 |
124 | Bulbar palsy (HP:0001283) | 1.75631883 |
125 | Acanthosis nigricans (HP:0000956) | 1.75345935 |
126 | Hemorrhage of the eye (HP:0011885) | 1.73992600 |
127 | Death in infancy (HP:0001522) | 1.73646594 |
128 | Premature skin wrinkling (HP:0100678) | 1.73604939 |
129 | Fasciculations (HP:0002380) | 1.73544302 |
130 | Back pain (HP:0003418) | 1.72487574 |
131 | Increased variability in muscle fiber diameter (HP:0003557) | 1.72399532 |
132 | Increased serum ferritin (HP:0003281) | 1.71742252 |
133 | Purpura (HP:0000979) | 1.71706654 |
134 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.71448633 |
135 | Abnormality of macrophages (HP:0004311) | 1.70535312 |
136 | Combined immunodeficiency (HP:0005387) | 1.70314369 |
137 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.68922537 |
138 | Cholelithiasis (HP:0001081) | 1.68767941 |
139 | Orthostatic hypotension (HP:0001278) | 1.68531290 |
140 | Interstitial pulmonary disease (HP:0006530) | 1.68493867 |
141 | Hyperthyroidism (HP:0000836) | 1.68369711 |
142 | Glossoptosis (HP:0000162) | 1.68352700 |
143 | Nuclear cataract (HP:0100018) | 1.67769977 |
144 | Ankle contracture (HP:0006466) | 1.67054294 |
145 | Progressive neurologic deterioration (HP:0002344) | 1.66725980 |
146 | Aplasia involving forearm bones (HP:0009822) | 1.66614524 |
147 | Absent forearm bone (HP:0003953) | 1.66614524 |
148 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.66379983 |
149 | Ependymoma (HP:0002888) | 1.66342666 |
150 | Muscle fiber atrophy (HP:0100295) | 1.66324220 |
151 | Fragile skin (HP:0001030) | 1.65191567 |
152 | Lymphoma (HP:0002665) | 1.65044055 |
153 | Difficulty climbing stairs (HP:0003551) | 1.64857184 |
154 | Vertebral compression fractures (HP:0002953) | 1.64679970 |
155 | Abnormality of the thoracic spine (HP:0100711) | 1.63515133 |
156 | Abnormality of the alveolar ridges (HP:0006477) | 1.62958064 |
157 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.62782137 |
158 | Abnormality of the calcaneus (HP:0008364) | 1.61427107 |
159 | Deformed tarsal bones (HP:0008119) | 1.61401441 |
160 | Proximal placement of thumb (HP:0009623) | 1.60597443 |
161 | Abnormality of reticulocytes (HP:0004312) | 1.60410440 |
162 | Impulsivity (HP:0100710) | 1.60296032 |
163 | Seborrheic dermatitis (HP:0001051) | 1.59414186 |
164 | Recurrent abscess formation (HP:0002722) | 1.58972669 |
165 | Joint stiffness (HP:0001387) | 1.58933794 |
166 | Polygenic inheritance (HP:0010982) | 1.58519347 |
167 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.58278685 |
168 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.58077043 |
169 | Atelectasis (HP:0100750) | 1.57999044 |
170 | Growth hormone excess (HP:0000845) | 1.57845926 |
171 | Broad alveolar ridges (HP:0000187) | 1.57689135 |
172 | Eczematoid dermatitis (HP:0000976) | 1.57157527 |
173 | Cerebral aneurysm (HP:0004944) | 1.56506465 |
174 | Biconcave vertebral bodies (HP:0004586) | 1.56377731 |
175 | Recurrent fungal infections (HP:0002841) | 1.56013477 |
176 | Tracheoesophageal fistula (HP:0002575) | 1.54473933 |
177 | Panhypogammaglobulinemia (HP:0003139) | 1.54409914 |
178 | Sparse lateral eyebrow (HP:0005338) | 1.54022569 |
179 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.53363383 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.53802687 |
2 | SMG1 | 3.44979381 |
3 | WEE1 | 3.04560938 |
4 | TESK2 | 2.86051873 |
5 | NME2 | 2.74214224 |
6 | NEK2 | 2.55180256 |
7 | VRK2 | 2.50884125 |
8 | TRIB3 | 2.49404691 |
9 | MAP4K1 | 2.41597747 |
10 | PIM2 | 2.26484449 |
11 | PRPF4B | 2.22672827 |
12 | EIF2AK1 | 2.17294520 |
13 | KDR | 2.16203840 |
14 | EEF2K | 2.11541203 |
15 | MAP3K10 | 2.09150782 |
16 | DYRK3 | 2.07424225 |
17 | TBK1 | 2.03991672 |
18 | EPHA2 | 2.02553455 |
19 | SIK1 | 2.01477598 |
20 | ERN1 | 1.88394260 |
21 | MAP3K11 | 1.88281012 |
22 | CDC7 | 1.74083949 |
23 | STK10 | 1.71631414 |
24 | STK16 | 1.65073801 |
25 | MAPKAPK3 | 1.64246897 |
26 | RPS6KA4 | 1.56445689 |
27 | TSSK6 | 1.53693423 |
28 | MAP3K8 | 1.53152649 |
29 | ZAP70 | 1.49015780 |
30 | GRK6 | 1.46267311 |
31 | PLK4 | 1.45928306 |
32 | TAOK1 | 1.45842825 |
33 | RPS6KB2 | 1.45703634 |
34 | LIMK1 | 1.42095347 |
35 | PAK4 | 1.39945339 |
36 | CDK7 | 1.36466018 |
37 | PLK1 | 1.34567324 |
38 | ACVR1B | 1.31551521 |
39 | TTK | 1.31546313 |
40 | ARAF | 1.28362096 |
41 | TLK1 | 1.27924993 |
42 | BLK | 1.26822551 |
43 | PKN2 | 1.25168361 |
44 | LRRK2 | 1.21876750 |
45 | TTN | 1.20064150 |
46 | CDK4 | 1.17864261 |
47 | TGFBR1 | 1.13967771 |
48 | AURKA | 1.09086591 |
49 | MAP2K2 | 1.07140215 |
50 | SCYL2 | 1.03519191 |
51 | TESK1 | 1.03483279 |
52 | ABL2 | 1.02585096 |
53 | CDK8 | 1.01408369 |
54 | AURKB | 1.00532213 |
55 | PIM1 | 0.94078739 |
56 | MAP2K3 | 0.92844214 |
57 | IKBKB | 0.92827750 |
58 | BCKDK | 0.92204407 |
59 | BRSK2 | 0.91681091 |
60 | PASK | 0.90176335 |
61 | FLT3 | 0.88605000 |
62 | IKBKE | 0.88047806 |
63 | BRAF | 0.86376896 |
64 | PAK1 | 0.85541388 |
65 | SRPK1 | 0.85336594 |
66 | BRSK1 | 0.84863031 |
67 | NEK1 | 0.81467020 |
68 | ATR | 0.80696855 |
69 | EIF2AK3 | 0.80681338 |
70 | MST1R | 0.79473750 |
71 | PRKCI | 0.78935788 |
72 | MAP3K1 | 0.78251034 |
73 | TAOK2 | 0.77993498 |
74 | VRK1 | 0.77428241 |
75 | LMTK2 | 0.76463254 |
76 | MAP3K3 | 0.76005196 |
77 | CHEK2 | 0.74532025 |
78 | TYK2 | 0.74241076 |
79 | DAPK1 | 0.73824121 |
80 | FGFR4 | 0.71935287 |
81 | PTK6 | 0.69179445 |
82 | CDK9 | 0.67789257 |
83 | MOS | 0.67610679 |
84 | JAK3 | 0.65747177 |
85 | RAF1 | 0.65679707 |
86 | IRAK2 | 0.64200038 |
87 | PRKD2 | 0.64016861 |
88 | MAP3K13 | 0.63287130 |
89 | LATS2 | 0.63059248 |
90 | PRKD3 | 0.62183263 |
91 | PTK2 | 0.58270402 |
92 | ALK | 0.57868710 |
93 | BTK | 0.57526455 |
94 | NLK | 0.57419562 |
95 | EPHB1 | 0.57003654 |
96 | ILK | 0.56857355 |
97 | CDK12 | 0.56670530 |
98 | BMX | 0.54134397 |
99 | TGFBR2 | 0.53201535 |
100 | DYRK2 | 0.53011777 |
101 | * CHEK1 | 0.49244731 |
102 | SIK3 | 0.48456991 |
103 | ICK | 0.47943842 |
104 | RPS6KC1 | 0.47017366 |
105 | RPS6KL1 | 0.47017366 |
106 | RPS6KA5 | 0.46937221 |
107 | CDK2 | 0.46514709 |
108 | CDC42BPA | 0.45912507 |
109 | PDPK1 | 0.45330113 |
110 | CDK11A | 0.43175222 |
111 | RPS6KA2 | 0.42909706 |
112 | PBK | 0.42830788 |
113 | EPHB2 | 0.42505460 |
114 | KSR2 | 0.41163465 |
115 | MTOR | 0.40868176 |
116 | MAPKAPK2 | 0.40435801 |
117 | PRKG2 | 0.38799689 |
118 | CHUK | 0.38759404 |
119 | MAPK11 | 0.38433753 |
120 | HIPK2 | 0.37932733 |
121 | KIT | 0.37675881 |
122 | PDGFRA | 0.37466603 |
123 | PAK2 | 0.37280045 |
124 | MAP3K14 | 0.36152599 |
125 | DAPK3 | 0.35915956 |
126 | AKT2 | 0.35871314 |
127 | CDK15 | 0.35222358 |
128 | RPS6KA1 | 0.33964954 |
129 | IRAK4 | 0.33381650 |
130 | CDK14 | 0.33017678 |
131 | CSNK2A2 | 0.32576520 |
132 | CCNB1 | 0.32178973 |
133 | IRAK3 | 0.31963774 |
134 | CSNK2A1 | 0.31545791 |
135 | STK4 | 0.30945117 |
136 | CSF1R | 0.30716938 |
137 | MARK2 | 0.30177263 |
138 | RIPK1 | 0.27636055 |
139 | PLK3 | 0.27278920 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.30888485 |
2 | Ribosome_Homo sapiens_hsa03010 | 3.65254723 |
3 | Proteasome_Homo sapiens_hsa03050 | 3.54087673 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.16191626 |
5 | Mismatch repair_Homo sapiens_hsa03430 | 3.08143116 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 3.06510003 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.00455905 |
8 | Base excision repair_Homo sapiens_hsa03410 | 2.85574062 |
9 | RNA transport_Homo sapiens_hsa03013 | 2.78479359 |
10 | Cell cycle_Homo sapiens_hsa04110 | 2.26749163 |
11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.24265537 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.12605637 |
13 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.97000979 |
14 | Homologous recombination_Homo sapiens_hsa03440 | 1.94194933 |
15 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.91458801 |
16 | Sulfur relay system_Homo sapiens_hsa04122 | 1.89868601 |
17 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.84541962 |
18 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.83713385 |
19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.79478182 |
20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.66395345 |
21 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.58316629 |
22 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.49797399 |
23 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.43170650 |
24 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.39227292 |
25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.37856628 |
26 | Prion diseases_Homo sapiens_hsa05020 | 1.35204218 |
27 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.30693748 |
28 | Lysosome_Homo sapiens_hsa04142 | 1.23904103 |
29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.23894582 |
30 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.19259265 |
31 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.15924101 |
32 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.15641840 |
33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.15467922 |
34 | Salmonella infection_Homo sapiens_hsa05132 | 1.13996909 |
35 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.10050675 |
36 | Shigellosis_Homo sapiens_hsa05131 | 1.08963422 |
37 | RNA degradation_Homo sapiens_hsa03018 | 1.08362197 |
38 | Purine metabolism_Homo sapiens_hsa00230 | 1.05127605 |
39 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.02999140 |
40 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.00998002 |
41 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.99537914 |
42 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.96132802 |
43 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.96013461 |
44 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.93139305 |
45 | Apoptosis_Homo sapiens_hsa04210 | 0.92136734 |
46 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.91563194 |
47 | Legionellosis_Homo sapiens_hsa05134 | 0.91254465 |
48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.91166345 |
49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.89087238 |
50 | HTLV-I infection_Homo sapiens_hsa05166 | 0.85668315 |
51 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.82399522 |
52 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.82050350 |
53 | Measles_Homo sapiens_hsa05162 | 0.80456166 |
54 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.79296536 |
55 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.77092188 |
56 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.76933376 |
57 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.74758583 |
58 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.74413985 |
59 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.74006200 |
60 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.73553356 |
61 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.71147787 |
62 | Other glycan degradation_Homo sapiens_hsa00511 | 0.70924942 |
63 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.69857886 |
64 | Thyroid cancer_Homo sapiens_hsa05216 | 0.69773370 |
65 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.69716657 |
66 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.69366017 |
67 | Endocytosis_Homo sapiens_hsa04144 | 0.68688368 |
68 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.66473811 |
69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.65855637 |
70 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.65218996 |
71 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.64619590 |
72 | Hepatitis B_Homo sapiens_hsa05161 | 0.64332671 |
73 | Bladder cancer_Homo sapiens_hsa05219 | 0.64149123 |
74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.63985282 |
75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.62328712 |
76 | Leishmaniasis_Homo sapiens_hsa05140 | 0.60920900 |
77 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.60860008 |
78 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.60684583 |
79 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.59204572 |
80 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.59035836 |
81 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.58442030 |
82 | Hepatitis C_Homo sapiens_hsa05160 | 0.58325418 |
83 | Tuberculosis_Homo sapiens_hsa05152 | 0.57150855 |
84 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.56838790 |
85 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53804947 |
86 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.53176155 |
87 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.53007970 |
88 | Alcoholism_Homo sapiens_hsa05034 | 0.52751615 |
89 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.52071266 |
90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.52021950 |
91 | Influenza A_Homo sapiens_hsa05164 | 0.50507420 |
92 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.50274278 |
93 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.50161579 |
94 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.49567427 |
95 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.49155911 |
96 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.48038117 |
97 | Phagosome_Homo sapiens_hsa04145 | 0.46682529 |
98 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.45000191 |
99 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.44344178 |
100 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44185221 |
101 | Colorectal cancer_Homo sapiens_hsa05210 | 0.43911791 |
102 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.42186623 |
103 | Glioma_Homo sapiens_hsa05214 | 0.42052993 |
104 | Huntingtons disease_Homo sapiens_hsa05016 | 0.41897551 |
105 | Viral myocarditis_Homo sapiens_hsa05416 | 0.41139865 |
106 | Parkinsons disease_Homo sapiens_hsa05012 | 0.40544241 |
107 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40234082 |
108 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.39745060 |
109 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.39031350 |
110 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.37980154 |
111 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.37947597 |
112 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.36973988 |
113 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.36746410 |
114 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.35308768 |
115 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.35049838 |
116 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.34951762 |
117 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.34101183 |
118 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.33571280 |
119 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.32498259 |
120 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.32467661 |
121 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32411847 |
122 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.30967659 |
123 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.30112511 |
124 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.27414858 |
125 | Pertussis_Homo sapiens_hsa05133 | 0.26822331 |
126 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.26138240 |
127 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.25505496 |
128 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.24747862 |
129 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.24619058 |
130 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.24457840 |
131 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.24213827 |
132 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.24159053 |