RBM43P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuronal action potential propagation (GO:0019227)8.24008098
2detection of light stimulus involved in sensory perception (GO:0050962)5.80368218
3detection of light stimulus involved in visual perception (GO:0050908)5.80368218
4cornea development in camera-type eye (GO:0061303)5.79996780
5keratinocyte development (GO:0003334)5.52741506
6seminiferous tubule development (GO:0072520)5.44957470
7positive regulation of inositol phosphate biosynthetic process (GO:0060732)5.25500648
8melanin biosynthetic process (GO:0042438)4.72360124
9melanin metabolic process (GO:0006582)4.41533774
10secondary metabolite biosynthetic process (GO:0044550)4.33308199
11cilium or flagellum-dependent cell motility (GO:0001539)4.32902789
12negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.31068239
13negative regulation of translation, ncRNA-mediated (GO:0040033)4.31068239
14regulation of translation, ncRNA-mediated (GO:0045974)4.31068239
15forebrain neuron differentiation (GO:0021879)4.29647544
16hindbrain development (GO:0030902)4.21286944
17regulation of chromatin binding (GO:0035561)4.07683037
18regulation of inositol phosphate biosynthetic process (GO:0010919)3.94255423
19Peyers patch development (GO:0048541)3.81865058
20mucosal-associated lymphoid tissue development (GO:0048537)3.81865058
21calcium-mediated signaling using intracellular calcium source (GO:0035584)3.78134415
22positive regulation of cAMP-mediated signaling (GO:0043950)3.77301977
23mechanosensory behavior (GO:0007638)3.76440629
24otic vesicle formation (GO:0030916)3.75746309
25sympathetic nervous system development (GO:0048485)3.69127281
26ketone body metabolic process (GO:1902224)3.63374459
27auditory behavior (GO:0031223)3.51787833
28serotonin metabolic process (GO:0042428)3.51503790
29uterus development (GO:0060065)3.50659255
30behavioral response to ethanol (GO:0048149)3.48048090
31primary amino compound metabolic process (GO:1901160)3.45830388
32postsynaptic membrane organization (GO:0001941)3.40925254
33regulation of DNA endoreduplication (GO:0032875)3.40310491
34regulation of posttranscriptional gene silencing (GO:0060147)3.37155082
35regulation of gene silencing by miRNA (GO:0060964)3.37155082
36regulation of gene silencing by RNA (GO:0060966)3.37155082
37protein localization to synapse (GO:0035418)3.34746687
38epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.33552575
39regulation of voltage-gated calcium channel activity (GO:1901385)3.31286252
40amine catabolic process (GO:0009310)3.26986213
41cellular biogenic amine catabolic process (GO:0042402)3.26986213
42cellular ketone body metabolic process (GO:0046950)3.22230646
43spinal cord development (GO:0021510)3.22021785
44eyelid development in camera-type eye (GO:0061029)3.15848600
45histone-serine phosphorylation (GO:0035404)3.14694029
46histone H4-K12 acetylation (GO:0043983)3.13868503
47regulation of hippo signaling (GO:0035330)3.10881977
48neural crest cell development (GO:0014032)3.05762313
49response to acidic pH (GO:0010447)3.02198065
50protein localization to microtubule cytoskeleton (GO:0072698)3.01927879
51protein-chromophore linkage (GO:0018298)3.01884598
52nonmotile primary cilium assembly (GO:0035058)3.01555052
53presynaptic membrane assembly (GO:0097105)3.00918890
54kinetochore assembly (GO:0051382)2.96406081
55negative regulation of transcription by competitive promoter binding (GO:0010944)2.95345150
56NLS-bearing protein import into nucleus (GO:0006607)2.94628121
57regulation of cilium movement (GO:0003352)2.93823836
58behavioral response to nicotine (GO:0035095)2.93106004
59negative regulation of axonogenesis (GO:0050771)2.91633304
60presynaptic membrane organization (GO:0097090)2.86693136
61neuronal action potential (GO:0019228)2.85000908
62embryonic body morphogenesis (GO:0010172)2.83141872
63adult walking behavior (GO:0007628)2.80842576
64indole-containing compound metabolic process (GO:0042430)2.79569030
65positive regulation of odontogenesis (GO:0042482)2.78408843
66retinal rod cell development (GO:0046548)2.78129108
67melanosome organization (GO:0032438)2.76725613
68positive regulation of mRNA metabolic process (GO:1903313)2.75965414
69spinal cord motor neuron differentiation (GO:0021522)2.75644276
70protein localization to cytoskeleton (GO:0044380)2.74412977
71detection of mechanical stimulus involved in sensory perception (GO:0050974)2.74207534
72synaptic transmission, cholinergic (GO:0007271)2.73693793
73endosome to pigment granule transport (GO:0043485)2.72780564
74endosome to melanosome transport (GO:0035646)2.72780564
75cardiovascular system development (GO:0072358)2.70986761
76resolution of meiotic recombination intermediates (GO:0000712)2.70027810
77chromatin remodeling at centromere (GO:0031055)2.68823439
78pigment granule organization (GO:0048753)2.68803718
79spinal cord association neuron differentiation (GO:0021527)2.68077829
80negative regulation of DNA-dependent DNA replication (GO:2000104)2.67941907
81photoreceptor cell development (GO:0042461)2.67784207
82positive regulation of mRNA processing (GO:0050685)2.67763897
83tachykinin receptor signaling pathway (GO:0007217)2.67720331
84kinetochore organization (GO:0051383)2.66868964
85oligosaccharide biosynthetic process (GO:0009312)2.66349830
86cerebellar Purkinje cell differentiation (GO:0021702)2.66100458
87negative regulation of synaptic transmission, GABAergic (GO:0032229)2.64108442
88DNA deamination (GO:0045006)2.63011304
89thymus development (GO:0048538)2.62751350
90axonemal dynein complex assembly (GO:0070286)2.62749396
91muscle atrophy (GO:0014889)2.61840539
92pyrimidine nucleobase catabolic process (GO:0006208)2.60392640
93CENP-A containing nucleosome assembly (GO:0034080)2.60127659
94gamma-aminobutyric acid signaling pathway (GO:0007214)2.57913812
95eye photoreceptor cell development (GO:0042462)2.57108015
96response to pheromone (GO:0019236)2.57034018
97protein localization to kinetochore (GO:0034501)2.55260423
98limb bud formation (GO:0060174)2.54468434
99regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.54255664
100gamma-aminobutyric acid transport (GO:0015812)10.8516519

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.49915626
2VDR_22108803_ChIP-Seq_LS180_Human3.78446425
3GBX2_23144817_ChIP-Seq_PC3_Human3.36371265
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.10565179
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.70603796
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.69131505
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.64517123
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.50577722
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.45851639
10CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.37818367
11ZNF274_21170338_ChIP-Seq_K562_Hela2.33775016
12TAF15_26573619_Chip-Seq_HEK293_Human2.32511286
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.27156895
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.25016266
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.19145234
16SALL1_21062744_ChIP-ChIP_HESCs_Human2.18405717
17EWS_26573619_Chip-Seq_HEK293_Human2.16641528
18P300_19829295_ChIP-Seq_ESCs_Human2.07158831
19RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.00126855
20FUS_26573619_Chip-Seq_HEK293_Human1.98923697
21SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.96753678
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92946487
23BCAT_22108803_ChIP-Seq_LS180_Human1.92301976
24IGF1R_20145208_ChIP-Seq_DFB_Human1.82455372
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.81765918
26AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.79692563
27MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.77656146
28SMAD4_21799915_ChIP-Seq_A2780_Human1.69996071
29POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.67631223
30TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.67631223
31STAT3_23295773_ChIP-Seq_U87_Human1.65775210
32AR_25329375_ChIP-Seq_VCAP_Human1.65242950
33SMAD3_21741376_ChIP-Seq_EPCs_Human1.64921269
34SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.64846270
35RNF2_27304074_Chip-Seq_NSC_Mouse1.63992900
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.60918003
37JARID2_20064375_ChIP-Seq_MESCs_Mouse1.58021782
38REST_21632747_ChIP-Seq_MESCs_Mouse1.56694523
39UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56259278
40TCF4_23295773_ChIP-Seq_U87_Human1.56043913
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54650170
42EZH2_27304074_Chip-Seq_ESCs_Mouse1.53718051
43SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51565598
44RUNX2_22187159_ChIP-Seq_PCA_Human1.50947749
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47482692
46ER_23166858_ChIP-Seq_MCF-7_Human1.47013510
47TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45503924
48TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40986388
49TP53_16413492_ChIP-PET_HCT116_Human1.38818551
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.37951427
51GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.37273898
52HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.36729468
53NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35811996
54SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.33880709
55KDM2B_26808549_Chip-Seq_REH_Human1.33128340
56IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31650673
57CBP_20019798_ChIP-Seq_JUKART_Human1.31650673
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.29243642
59EZH2_18974828_ChIP-Seq_MESCs_Mouse1.28807595
60RNF2_18974828_ChIP-Seq_MESCs_Mouse1.28807595
61PRDM14_20953172_ChIP-Seq_ESCs_Human1.27609914
62SOX2_21211035_ChIP-Seq_LN229_Gbm1.26930357
63SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.23113423
64SMAD3_21741376_ChIP-Seq_HESCs_Human1.22443346
65FLI1_21867929_ChIP-Seq_TH2_Mouse1.22066117
66LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20435736
67FLI1_27457419_Chip-Seq_LIVER_Mouse1.20009293
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19531399
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.19304852
70EED_16625203_ChIP-ChIP_MESCs_Mouse1.18645494
71GATA1_22025678_ChIP-Seq_K562_Human1.16836098
72TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.14693707
73EZH2_27294783_Chip-Seq_NPCs_Mouse1.14319391
74SMAD4_21741376_ChIP-Seq_EPCs_Human1.13259275
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12358722
76TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10600082
77SMAD3_21741376_ChIP-Seq_ESCs_Human1.10052318
78JARID2_20075857_ChIP-Seq_MESCs_Mouse1.08928123
79NCOR_22424771_ChIP-Seq_293T_Human1.08835778
80OCT1_27270436_Chip-Seq_PROSTATE_Human1.08217309
81SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.07519359
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.06956369
83EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06744818
84TCF4_22108803_ChIP-Seq_LS180_Human1.06657715
85JUN_21703547_ChIP-Seq_K562_Human1.06174902
86SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.05217700
87FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.04358527
88AHR_22903824_ChIP-Seq_MCF-7_Human1.02297793
89NRF2_20460467_ChIP-Seq_MEFs_Mouse1.01504094
90NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.01504094
91RNF2_27304074_Chip-Seq_ESCs_Mouse1.00530183
92SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.99496646
93GATA1_26923725_Chip-Seq_HPCs_Mouse0.99403573
94NANOG_18555785_Chip-Seq_ESCs_Mouse0.98992716
95SMAD4_21741376_ChIP-Seq_HESCs_Human0.98417668
96IRF1_19129219_ChIP-ChIP_H3396_Human0.97604194
97NOTCH1_21737748_ChIP-Seq_TLL_Human0.97062719
98POU5F1_16153702_ChIP-ChIP_HESCs_Human0.96844504
99SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.96482972
100KLF5_20875108_ChIP-Seq_MESCs_Mouse0.96378514

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation5.23557566
2MP0004858_abnormal_nervous_system4.64169406
3MP0003880_abnormal_central_pattern4.04296384
4MP0002102_abnormal_ear_morphology3.39056343
5MP0003136_yellow_coat_color3.30187680
6MP0005075_abnormal_melanosome_morpholog3.29832418
7MP0005423_abnormal_somatic_nervous3.04087074
8MP0005408_hypopigmentation2.98828380
9MP0001986_abnormal_taste_sensitivity2.94889734
10MP0005187_abnormal_penis_morphology2.85847837
11MP0000569_abnormal_digit_pigmentation2.78179428
12MP0005171_absent_coat_pigmentation2.45464820
13MP0000015_abnormal_ear_pigmentation2.40978773
14MP0006276_abnormal_autonomic_nervous2.38558154
15MP0003122_maternal_imprinting2.23521001
16MP0005645_abnormal_hypothalamus_physiol2.23086481
17MP0002138_abnormal_hepatobiliary_system2.11327800
18MP0005174_abnormal_tail_pigmentation2.09086942
19MP0003121_genomic_imprinting1.96771302
20MP0004142_abnormal_muscle_tone1.89848926
21MP0009046_muscle_twitch1.85671301
22MP0005551_abnormal_eye_electrophysiolog1.84865286
23MP0002272_abnormal_nervous_system1.84328951
24MP0001324_abnormal_eye_pigmentation1.80047737
25MP0005499_abnormal_olfactory_system1.69219934
26MP0005394_taste/olfaction_phenotype1.69219934
27MP0001188_hyperpigmentation1.68682443
28MP0003890_abnormal_embryonic-extraembry1.66069945
29MP0004381_abnormal_hair_follicle1.57124878
30MP0008789_abnormal_olfactory_epithelium1.56843711
31MP0004924_abnormal_behavior1.55577226
32MP0005386_behavior/neurological_phenoty1.55577226
33MP0001968_abnormal_touch/_nociception1.55359859
34MP0002160_abnormal_reproductive_system1.51476600
35MP0009745_abnormal_behavioral_response1.50490150
36MP0003787_abnormal_imprinting1.49685911
37MP0002095_abnormal_skin_pigmentation1.45901462
38MP0006292_abnormal_olfactory_placode1.45741983
39MP0002938_white_spotting1.45581092
40MP0002736_abnormal_nociception_after1.44615198
41MP0005389_reproductive_system_phenotype1.39902862
42MP0001529_abnormal_vocalization1.38787260
43MP0000647_abnormal_sebaceous_gland1.37270358
44MP0002184_abnormal_innervation1.37068552
45MP0003119_abnormal_digestive_system1.33359753
46MP0001440_abnormal_grooming_behavior1.33025752
47MP0010234_abnormal_vibrissa_follicle1.32621066
48MP0003868_abnormal_feces_composition1.30420878
49MP0004885_abnormal_endolymph1.28770223
50MP0003315_abnormal_perineum_morphology1.27326646
51MP0003385_abnormal_body_wall1.25361832
52MP0005248_abnormal_Harderian_gland1.23449213
53MP0001486_abnormal_startle_reflex1.23165833
54MP0000778_abnormal_nervous_system1.22204541
55MP0000631_abnormal_neuroendocrine_gland1.16140428
56MP0003635_abnormal_synaptic_transmissio1.12128782
57MP0008877_abnormal_DNA_methylation1.11851094
58MP0000427_abnormal_hair_cycle1.11826652
59MP0002557_abnormal_social/conspecific_i1.08013926
60MP0002572_abnormal_emotion/affect_behav1.06361512
61MP0000371_diluted_coat_color1.06340031
62MP0002067_abnormal_sensory_capabilities1.05353515
63MP0008058_abnormal_DNA_repair1.04857500
64MP0002734_abnormal_mechanical_nocicepti1.03106767
65MP0002063_abnormal_learning/memory/cond1.02306665
66MP0000955_abnormal_spinal_cord1.02001858
67MP0003195_calcinosis0.98799669
68MP0005253_abnormal_eye_physiology0.98236094
69MP0002752_abnormal_somatic_nervous0.97747926
70MP0002733_abnormal_thermal_nociception0.95204713
71MP0001919_abnormal_reproductive_system0.94623999
72MP0003866_abnormal_defecation0.92696694
73MP0002735_abnormal_chemical_nociception0.91204348
74MP0002822_catalepsy0.86655842
75MP0002928_abnormal_bile_duct0.86174420
76MP0005671_abnormal_response_to0.85983766
77MP0002064_seizures0.83987023
78MP0005220_abnormal_exocrine_pancreas0.83754791
79MP0002882_abnormal_neuron_morphology0.82203570
80MP0010094_abnormal_chromosome_stability0.78450845
81MP0001970_abnormal_pain_threshold0.77768627
82MP0004133_heterotaxia0.74498239
83MP0001984_abnormal_olfaction0.72731448
84MP0005647_abnormal_sex_gland0.71888979
85MP0003698_abnormal_male_reproductive0.71210411
86MP0002233_abnormal_nose_morphology0.68436871
87MP0003935_abnormal_craniofacial_develop0.67787958
88MP0001293_anophthalmia0.67580284
89MP0002152_abnormal_brain_morphology0.63281529
90MP0003075_altered_response_to0.62924219
91MP0002090_abnormal_vision0.62726507
92MP0004742_abnormal_vestibular_system0.62615680
93MP0001501_abnormal_sleep_pattern0.60236613
94MP0008872_abnormal_physiological_respon0.59593561
95MP0000026_abnormal_inner_ear0.59195445
96MP0002066_abnormal_motor_capabilities/c0.58696936
97MP0002653_abnormal_ependyma_morphology0.58648282
98MP0001485_abnormal_pinna_reflex0.58301954
99MP0002234_abnormal_pharynx_morphology0.58250758
100MP0003861_abnormal_nervous_system0.57209576

Predicted human phenotypes

RankGene SetZ-score
1Hyperventilation (HP:0002883)5.19933916
2Atonic seizures (HP:0010819)4.95274729
3Abnormality of the labia minora (HP:0012880)4.68644873
4Failure to thrive in infancy (HP:0001531)4.64513996
5Bilateral sensorineural hearing impairment (HP:0008619)4.56106634
6Pancreatic fibrosis (HP:0100732)4.02210651
7Febrile seizures (HP:0002373)3.96386139
8Pancreatic cysts (HP:0001737)3.59202925
9Medial flaring of the eyebrow (HP:0010747)3.47200331
10Protruding tongue (HP:0010808)3.46053471
11Gaze-evoked nystagmus (HP:0000640)3.45364372
12Enlarged penis (HP:0000040)3.41811558
13Oligomenorrhea (HP:0000876)3.38575577
14True hermaphroditism (HP:0010459)3.35235795
15Molar tooth sign on MRI (HP:0002419)3.29384569
16Abnormality of midbrain morphology (HP:0002418)3.29384569
17Gait imbalance (HP:0002141)3.28430959
18Adrenal hypoplasia (HP:0000835)3.18694383
19White forelock (HP:0002211)3.15671932
20Abnormality of the renal cortex (HP:0011035)3.14196956
21Volvulus (HP:0002580)3.10751361
22Inappropriate behavior (HP:0000719)3.04845728
23Congenital primary aphakia (HP:0007707)3.02828609
24Nephronophthisis (HP:0000090)3.01974970
25Abnormal hair whorl (HP:0010721)3.01796665
26Abnormality of the nasal septum (HP:0000419)3.01402089
27Poor coordination (HP:0002370)2.91568833
28Nephrogenic diabetes insipidus (HP:0009806)2.89230136
29Patchy hypopigmentation of hair (HP:0011365)2.77761730
30Dyskinesia (HP:0100660)2.75931702
31Broad-based gait (HP:0002136)2.75174392
32Polyphagia (HP:0002591)2.74017467
33Status epilepticus (HP:0002133)2.73619343
34Megalencephaly (HP:0001355)2.71540762
35Morphological abnormality of the middle ear (HP:0008609)2.71006210
36Small hand (HP:0200055)2.70257488
37Chronic otitis media (HP:0000389)2.69792331
38Drooling (HP:0002307)2.69201133
39Abnormality of the renal medulla (HP:0100957)2.68289164
40Cystic liver disease (HP:0006706)2.66574752
41Iris hypopigmentation (HP:0007730)2.66075494
42Absence seizures (HP:0002121)2.65661679
43Renal cortical cysts (HP:0000803)2.65070414
44Abnormal drinking behavior (HP:0030082)2.64874084
45Polydipsia (HP:0001959)2.64874084
46Abnormal respiratory epithelium morphology (HP:0012253)2.62171190
47Abnormal respiratory motile cilium morphology (HP:0005938)2.62171190
48Genital tract atresia (HP:0001827)2.61689816
49Epileptic encephalopathy (HP:0200134)2.52295110
50Vaginal atresia (HP:0000148)2.51672285
51Clumsiness (HP:0002312)2.49686274
52Excessive salivation (HP:0003781)2.47452590
53Focal motor seizures (HP:0011153)2.45917402
54Aplasia/Hypoplasia of the tongue (HP:0010295)2.45647523
55Curly hair (HP:0002212)2.37034884
56Aplasia/Hypoplasia of the fovea (HP:0008060)2.36889824
57Hypoplasia of the fovea (HP:0007750)2.36889824
58Aplasia/Hypoplasia of the tibia (HP:0005772)2.33752120
59Generalized hypopigmentation (HP:0007513)2.33514801
60Congenital hepatic fibrosis (HP:0002612)2.33394520
61Genetic anticipation (HP:0003743)2.31551315
62Generalized hypopigmentation of hair (HP:0011358)2.31446019
63Abnormality of dentin (HP:0010299)2.27655844
64Astigmatism (HP:0000483)2.26406108
65Sleep apnea (HP:0010535)2.24526774
66Absent speech (HP:0001344)2.22148471
67Sclerocornea (HP:0000647)2.21639393
68Hip dysplasia (HP:0001385)2.21039982
69Dialeptic seizures (HP:0011146)2.19676803
70Fair hair (HP:0002286)2.18670387
71Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16982783
72Absent/shortened dynein arms (HP:0200106)2.15114321
73Dynein arm defect of respiratory motile cilia (HP:0012255)2.15114321
74Aplasia cutis congenita (HP:0001057)2.14093817
75Supernumerary spleens (HP:0009799)2.14001835
76Focal seizures (HP:0007359)2.11359979
77Postaxial foot polydactyly (HP:0001830)2.10668634
78Pendular nystagmus (HP:0012043)2.09523563
79Blue irides (HP:0000635)2.08214300
80Tubulointerstitial abnormality (HP:0001969)2.07238913
81Generalized myoclonic seizures (HP:0002123)2.05971633
82Preaxial hand polydactyly (HP:0001177)2.01558317
83Gonadotropin excess (HP:0000837)2.00755171
84Polyuria (HP:0000103)1.98055882
85Abnormality of the dental pulp (HP:0006479)1.96273329
86Abnormality of the aortic arch (HP:0012303)1.95853662
87Aplasia/Hypoplasia of the macula (HP:0008059)1.95482207
88Abnormal auditory evoked potentials (HP:0006958)1.93696079
89Gastroesophageal reflux (HP:0002020)1.92563231
90Tubulointerstitial nephritis (HP:0001970)1.91618342
91Congenital stationary night blindness (HP:0007642)1.91563247
92Specific learning disability (HP:0001328)1.91031410
93Scrotal hypoplasia (HP:0000046)1.90900227
94Lip pit (HP:0100267)1.90869328
95Tubular atrophy (HP:0000092)1.89917948
96Poor suck (HP:0002033)1.89669620
97Abnormal lung lobation (HP:0002101)1.88941871
98Anencephaly (HP:0002323)1.88917712
99Tubulointerstitial fibrosis (HP:0005576)1.87649108
100Congenital sensorineural hearing impairment (HP:0008527)1.84693494

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.05520700
2FRK3.92757193
3PLK43.27197538
4MAPK132.57764690
5BUB12.51922218
6BMPR1B2.44039362
7MKNK22.40357611
8EPHA42.37106924
9INSRR2.18498062
10MAP3K42.13586583
11MAP3K92.13440748
12NEK12.11400665
13TRIM282.05724826
14ACVR1B1.88542789
15WNK31.88307849
16MARK11.85431095
17PINK11.78740752
18WEE11.76676392
19MAP3K61.74564642
20MAP2K71.72838555
21PNCK1.65224201
22STK391.60553290
23PTK2B1.55200168
24WNK41.48315383
25NEK21.47634081
26TNIK1.40152612
27PLK21.40076589
28TIE11.36841089
29GRK11.33851655
30ZAK1.27985698
31CAMK1G1.27499408
32PRKCQ1.24554083
33ICK1.21439014
34MARK31.17563369
35MKNK11.17386776
36PRKCG1.11927642
37TLK11.11232735
38PDK21.10856227
39CAMK1D1.04745993
40CAMK10.97425254
41PLK30.93089975
42OXSR10.92967307
43BRAF0.91168602
44PKN10.86741742
45ARAF0.86633157
46ADRBK20.85849469
47MINK10.85547375
48AKT30.83287660
49PIK3CA0.83249219
50SIK20.83003456
51PLK10.82364008
52IRAK10.81718953
53BRSK20.80385184
54PRKD30.80095508
55MAP3K130.79104154
56MAP2K40.77853493
57CSNK1D0.76298876
58NUAK10.74218648
59CSNK1G10.71377165
60TEC0.69628339
61ADRBK10.68985540
62CAMKK20.68973888
63BCR0.67085858
64PRKCE0.60817080
65BRSK10.60047056
66SGK20.59654090
67NTRK30.59348829
68NTRK20.58250039
69ERBB30.55860193
70DYRK20.55478584
71CDK30.53799709
72FGFR20.53554804
73EIF2AK20.52707252
74LMTK20.49714658
75CSNK1G20.48611670
76DYRK30.47077377
77PRKD10.45801860
78VRK10.40816359
79STK100.40608013
80CAMK40.40178438
81PRKCH0.39922039
82RAF10.39773677
83CAMK2A0.39348283
84DYRK1A0.38257043
85PRKAA10.36173750
86MAP3K140.35811325
87NEK90.31137715
88ATM0.30809523
89ERBB20.30271104
90TGFBR10.29817555
91PRKACA0.28812558
92STK110.27949632
93CSNK1G30.27927569
94PRKCZ0.27570535
95SGK30.27072584
96ERBB40.25587933
97CDC70.25404494
98CDK190.24827022
99ROCK10.23503434
100PRKG10.23298157

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.93721582
2Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.54012343
3Sulfur relay system_Homo sapiens_hsa041223.28738694
4Steroid biosynthesis_Homo sapiens_hsa001003.18570679
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.17774855
6Butanoate metabolism_Homo sapiens_hsa006503.03704914
7Dorso-ventral axis formation_Homo sapiens_hsa043202.88717549
8Linoleic acid metabolism_Homo sapiens_hsa005912.80153740
9Nicotine addiction_Homo sapiens_hsa050332.68615112
10Homologous recombination_Homo sapiens_hsa034402.25135448
11Fanconi anemia pathway_Homo sapiens_hsa034601.97554966
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.87506666
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.86650467
14Nitrogen metabolism_Homo sapiens_hsa009101.86077678
15Ether lipid metabolism_Homo sapiens_hsa005651.79550803
16Ovarian steroidogenesis_Homo sapiens_hsa049131.68348931
17Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.61099007
18Fatty acid biosynthesis_Homo sapiens_hsa000611.49103742
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.39904024
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35332902
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.34712343
22Phototransduction_Homo sapiens_hsa047441.32806770
23RNA polymerase_Homo sapiens_hsa030201.21371948
24Taste transduction_Homo sapiens_hsa047421.20125123
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.18862643
26Morphine addiction_Homo sapiens_hsa050321.16406286
27Fatty acid metabolism_Homo sapiens_hsa012121.14217160
28Glutamatergic synapse_Homo sapiens_hsa047241.04428071
29Calcium signaling pathway_Homo sapiens_hsa040201.03682195
30Basal transcription factors_Homo sapiens_hsa030221.01266170
31Tryptophan metabolism_Homo sapiens_hsa003801.00696586
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.99876135
33One carbon pool by folate_Homo sapiens_hsa006700.99540373
34Cyanoamino acid metabolism_Homo sapiens_hsa004600.97393133
35Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.97217089
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.96339442
37Propanoate metabolism_Homo sapiens_hsa006400.96174011
38Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.94831930
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94703054
40Serotonergic synapse_Homo sapiens_hsa047260.94045325
41Selenocompound metabolism_Homo sapiens_hsa004500.92070178
42Non-homologous end-joining_Homo sapiens_hsa034500.91810718
43Olfactory transduction_Homo sapiens_hsa047400.90800532
44Long-term depression_Homo sapiens_hsa047300.88880603
45Oxytocin signaling pathway_Homo sapiens_hsa049210.85484116
46Axon guidance_Homo sapiens_hsa043600.84471370
47Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.84399811
48ABC transporters_Homo sapiens_hsa020100.83718447
49Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.82355345
50Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.82040774
51Circadian entrainment_Homo sapiens_hsa047130.79672005
52RNA degradation_Homo sapiens_hsa030180.79536882
53Arachidonic acid metabolism_Homo sapiens_hsa005900.74400987
54Oocyte meiosis_Homo sapiens_hsa041140.73747959
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71367697
56Insulin secretion_Homo sapiens_hsa049110.68729019
57GABAergic synapse_Homo sapiens_hsa047270.67319925
58Starch and sucrose metabolism_Homo sapiens_hsa005000.65970400
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.61513721
60Glycerolipid metabolism_Homo sapiens_hsa005610.61217458
61Gastric acid secretion_Homo sapiens_hsa049710.59651408
62Melanogenesis_Homo sapiens_hsa049160.58072155
63Cholinergic synapse_Homo sapiens_hsa047250.56621657
64Dopaminergic synapse_Homo sapiens_hsa047280.56166045
65Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.55940322
66Cardiac muscle contraction_Homo sapiens_hsa042600.55072858
67Glycerophospholipid metabolism_Homo sapiens_hsa005640.54227506
68Sulfur metabolism_Homo sapiens_hsa009200.53810448
69cAMP signaling pathway_Homo sapiens_hsa040240.53636518
70DNA replication_Homo sapiens_hsa030300.52765330
71Ras signaling pathway_Homo sapiens_hsa040140.51500613
72Retinol metabolism_Homo sapiens_hsa008300.51485995
73Vascular smooth muscle contraction_Homo sapiens_hsa042700.50531737
74Melanoma_Homo sapiens_hsa052180.49747231
75Steroid hormone biosynthesis_Homo sapiens_hsa001400.49480139
76beta-Alanine metabolism_Homo sapiens_hsa004100.46894675
77Arginine and proline metabolism_Homo sapiens_hsa003300.46597801
78Cocaine addiction_Homo sapiens_hsa050300.46345335
79Choline metabolism in cancer_Homo sapiens_hsa052310.45008324
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.43435268
81MAPK signaling pathway_Homo sapiens_hsa040100.41571196
82Salivary secretion_Homo sapiens_hsa049700.40920228
83Mismatch repair_Homo sapiens_hsa034300.39693701
84Pyrimidine metabolism_Homo sapiens_hsa002400.38156302
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36502846
86Peroxisome_Homo sapiens_hsa041460.35494865
87Bile secretion_Homo sapiens_hsa049760.35473887
88Basal cell carcinoma_Homo sapiens_hsa052170.34969186
89Primary bile acid biosynthesis_Homo sapiens_hsa001200.34587519
90Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.34183394
91Amphetamine addiction_Homo sapiens_hsa050310.33651026
92Fatty acid elongation_Homo sapiens_hsa000620.31448791
93Cysteine and methionine metabolism_Homo sapiens_hsa002700.31024318
94Longevity regulating pathway - mammal_Homo sapiens_hsa042110.30666664
95Rap1 signaling pathway_Homo sapiens_hsa040150.30125930
96Purine metabolism_Homo sapiens_hsa002300.29588967
97Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28640954
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27566830
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.27270886
100Vitamin digestion and absorption_Homo sapiens_hsa049770.27044315

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