RBM48

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neural tube formation (GO:0001841)3.94764636
2water-soluble vitamin biosynthetic process (GO:0042364)3.93533997
3proteasome assembly (GO:0043248)3.88130481
4response to pheromone (GO:0019236)3.87333370
5protein-cofactor linkage (GO:0018065)3.82740635
6DNA replication checkpoint (GO:0000076)3.70999574
7CENP-A containing nucleosome assembly (GO:0034080)3.69913236
8DNA replication initiation (GO:0006270)3.67101243
9mitotic metaphase plate congression (GO:0007080)3.66515493
10DNA strand elongation involved in DNA replication (GO:0006271)3.59448677
11chromatin remodeling at centromere (GO:0031055)3.59237553
12regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.57863459
13meiotic chromosome segregation (GO:0045132)3.57418511
14behavioral response to nicotine (GO:0035095)3.55116415
15respiratory chain complex IV assembly (GO:0008535)3.51611615
16platelet dense granule organization (GO:0060155)3.50788374
17attachment of spindle microtubules to kinetochore (GO:0008608)3.46340121
18DNA strand elongation (GO:0022616)3.46037453
19metaphase plate congression (GO:0051310)3.45435098
20telomere maintenance via semi-conservative replication (GO:0032201)3.45416851
21protein complex biogenesis (GO:0070271)3.43762473
22DNA deamination (GO:0045006)3.40234931
23termination of RNA polymerase III transcription (GO:0006386)3.39525910
24transcription elongation from RNA polymerase III promoter (GO:0006385)3.39525910
25mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.38717514
26mitochondrial respiratory chain complex I assembly (GO:0032981)3.38717514
27NADH dehydrogenase complex assembly (GO:0010257)3.38717514
28RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.36576920
29preassembly of GPI anchor in ER membrane (GO:0016254)3.34063011
307-methylguanosine mRNA capping (GO:0006370)3.29472486
317-methylguanosine RNA capping (GO:0009452)3.26418395
32RNA capping (GO:0036260)3.26418395
33telomere maintenance via recombination (GO:0000722)3.26039438
34DNA double-strand break processing (GO:0000729)3.22926586
35mitochondrial respiratory chain complex assembly (GO:0033108)3.22795169
36protein K6-linked ubiquitination (GO:0085020)3.21043117
37replication fork processing (GO:0031297)3.17870909
38DNA replication-independent nucleosome organization (GO:0034724)3.15994124
39DNA replication-independent nucleosome assembly (GO:0006336)3.15994124
40histone exchange (GO:0043486)3.15846303
41detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.15039081
42ribosomal small subunit assembly (GO:0000028)3.14855493
43maturation of SSU-rRNA (GO:0030490)3.13783075
44mannosylation (GO:0097502)3.11363832
45L-fucose catabolic process (GO:0042355)3.10204333
46fucose catabolic process (GO:0019317)3.10204333
47L-fucose metabolic process (GO:0042354)3.10204333
48mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.09341938
49establishment of chromosome localization (GO:0051303)3.07833605
50regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.07579005
51positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.06556433
52ribosome biogenesis (GO:0042254)3.05969930
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.04072003
54ribosome assembly (GO:0042255)3.02910900
55mitotic recombination (GO:0006312)3.01953436
56anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.01833582
57cytochrome complex assembly (GO:0017004)3.01280027
58nucleobase biosynthetic process (GO:0046112)3.00763023
59DNA demethylation (GO:0080111)3.00119056
60telomere maintenance via telomere lengthening (GO:0010833)2.99402685
61ribosomal large subunit biogenesis (GO:0042273)2.98561278
62protein neddylation (GO:0045116)2.98378497
63regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.97935572
64retinal cone cell development (GO:0046549)2.97661374
65somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.97441990
66isotype switching (GO:0045190)2.97441990
67somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.97441990
68mitochondrial RNA metabolic process (GO:0000959)2.96305875
69tryptophan catabolic process (GO:0006569)2.95501883
70indole-containing compound catabolic process (GO:0042436)2.95501883
71indolalkylamine catabolic process (GO:0046218)2.95501883
72RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.94445530
73tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.94445530
74termination of RNA polymerase I transcription (GO:0006363)2.94268345
75transcription elongation from RNA polymerase I promoter (GO:0006362)2.94043098
76ribonucleoprotein complex biogenesis (GO:0022613)2.93197986
77negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.92780661
78formation of translation preinitiation complex (GO:0001731)2.92694044
79maturation of 5.8S rRNA (GO:0000460)2.92433780
80negative regulation of mitotic sister chromatid separation (GO:2000816)2.91566661
81negative regulation of mitotic sister chromatid segregation (GO:0033048)2.91566661
82negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.91566661
83negative regulation of sister chromatid segregation (GO:0033046)2.91566661
84transcription-coupled nucleotide-excision repair (GO:0006283)2.91190758
85centriole replication (GO:0007099)2.90954359
86spindle checkpoint (GO:0031577)2.90914497
87mismatch repair (GO:0006298)2.90854980
88DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.89145678
89signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.88430223
90signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.88430223
91signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.88430223
92nucleotide-excision repair, DNA gap filling (GO:0006297)2.86971669
93regulation of nuclear cell cycle DNA replication (GO:0033262)2.86345275
94rRNA modification (GO:0000154)2.86191741
95negative regulation of DNA-templated transcription, elongation (GO:0032785)2.86151515
96negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.86151515
97negative regulation of chromosome segregation (GO:0051985)2.85808552
98rRNA catabolic process (GO:0016075)2.85662353
99DNA unwinding involved in DNA replication (GO:0006268)2.85562156
100male meiosis (GO:0007140)2.85363706
101signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.84974581
102intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.84974581
103transcription from mitochondrial promoter (GO:0006390)2.84715595
104mitotic spindle assembly checkpoint (GO:0007094)2.84446536
105piRNA metabolic process (GO:0034587)2.83708650
106spindle assembly checkpoint (GO:0071173)2.83628266
107regulation of double-strand break repair via homologous recombination (GO:0010569)2.83457554
108regulation of meiosis I (GO:0060631)2.83238984
109negative regulation of transcription regulatory region DNA binding (GO:2000678)2.83105335
110exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.82196764
111regulation of histone H3-K27 methylation (GO:0061085)2.81455174
112somatic diversification of immune receptors via somatic mutation (GO:0002566)2.80618696
113somatic hypermutation of immunoglobulin genes (GO:0016446)2.80618696
114purine nucleobase biosynthetic process (GO:0009113)2.80411653
115transcription from RNA polymerase I promoter (GO:0006360)2.79844755
116L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.79676175
117mitotic spindle checkpoint (GO:0071174)2.79386156
118signal transduction involved in DNA integrity checkpoint (GO:0072401)2.77720523
119signal transduction involved in DNA damage checkpoint (GO:0072422)2.77720523
120protein K11-linked deubiquitination (GO:0035871)2.77229420
121signal transduction involved in cell cycle checkpoint (GO:0072395)2.76358490
122GPI anchor metabolic process (GO:0006505)2.76029021
123establishment of protein localization to mitochondrial membrane (GO:0090151)2.75561547
124tryptophan metabolic process (GO:0006568)2.74295131
125regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.73989516
126protein localization to kinetochore (GO:0034501)2.72946523
127regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.72719868
128cell cycle G1/S phase transition (GO:0044843)2.72625455
129G1/S transition of mitotic cell cycle (GO:0000082)2.72625455
130nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.72551908
131negative regulation of ligase activity (GO:0051352)2.72041426
132negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.72041426
133indolalkylamine metabolic process (GO:0006586)2.71492239
134regulation of mitotic metaphase/anaphase transition (GO:0030071)2.71321663
135DNA catabolic process, exonucleolytic (GO:0000738)2.70217056
136positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.68526872
137antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.67525743
138regulation of mitotic sister chromatid separation (GO:0010965)2.66601924
139regulation of mitotic sister chromatid segregation (GO:0033047)2.66601924
140regulation of sister chromatid segregation (GO:0033045)2.66601924
141rRNA processing (GO:0006364)2.65948662
142anterograde synaptic vesicle transport (GO:0048490)2.65261335
143ubiquinone biosynthetic process (GO:0006744)2.65032735
144telomere maintenance (GO:0000723)2.63816024
145tRNA processing (GO:0008033)2.63745045
146organelle disassembly (GO:1903008)2.63686374
147negative regulation of telomere maintenance (GO:0032205)2.63532553
148telomere organization (GO:0032200)2.63439941
149DNA methylation involved in gamete generation (GO:0043046)2.63249488
150amino acid salvage (GO:0043102)2.63174102
151L-methionine salvage (GO:0071267)2.63174102
152L-methionine biosynthetic process (GO:0071265)2.63174102
153pseudouridine synthesis (GO:0001522)2.62650923
154cytidine deamination (GO:0009972)2.62207032
155cytidine metabolic process (GO:0046087)2.62207032
156cytidine catabolic process (GO:0006216)2.62207032
157recombinational repair (GO:0000725)2.60968087
158double-strand break repair via homologous recombination (GO:0000724)2.59426855
159histone H2A acetylation (GO:0043968)2.59254873
160mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.58962621
161methionine biosynthetic process (GO:0009086)2.58142462
162male meiosis I (GO:0007141)2.57331614
163axoneme assembly (GO:0035082)2.56548920
164intraciliary transport (GO:0042073)2.52260719
165rRNA methylation (GO:0031167)2.51667349
166signal peptide processing (GO:0006465)2.51036089
167ubiquinone metabolic process (GO:0006743)2.50601861
168epithelial cilium movement (GO:0003351)2.48935882
169negative regulation of DNA-dependent DNA replication (GO:2000104)2.48750220
170cullin deneddylation (GO:0010388)2.47946994
171energy coupled proton transport, down electrochemical gradient (GO:0015985)2.47090629
172ATP synthesis coupled proton transport (GO:0015986)2.47090629
173resolution of meiotic recombination intermediates (GO:0000712)2.44592919
174somite development (GO:0061053)2.43182415
175transcription from RNA polymerase III promoter (GO:0006383)2.42890647
176detection of light stimulus involved in visual perception (GO:0050908)2.42212393
177detection of light stimulus involved in sensory perception (GO:0050962)2.42212393
178histone mRNA metabolic process (GO:0008334)2.40759375
179C-terminal protein lipidation (GO:0006501)2.40500409
180adaptation of signaling pathway (GO:0023058)2.39484720
181regulation of cilium movement (GO:0003352)2.38959463
182oxidative demethylation (GO:0070989)2.37855083
183nonmotile primary cilium assembly (GO:0035058)2.36964565
184epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.36780626
185kynurenine metabolic process (GO:0070189)2.36618674
186dopamine transport (GO:0015872)2.35873528

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.34708985
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.76157907
3ZNF274_21170338_ChIP-Seq_K562_Hela3.40779782
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.39231622
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.35225446
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.23706090
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.18984556
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.04537881
9VDR_22108803_ChIP-Seq_LS180_Human3.00496174
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.87021882
11* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.80273830
12FOXM1_23109430_ChIP-Seq_U2OS_Human2.73666497
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.73182596
14VDR_23849224_ChIP-Seq_CD4+_Human2.70678763
15POU3F2_20337985_ChIP-ChIP_501MEL_Human2.63250925
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.62931193
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.55805657
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.49761258
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.41283411
20MYC_19030024_ChIP-ChIP_MESCs_Mouse2.38066032
21EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.31479419
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.31392354
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.28244201
24MYC_18358816_ChIP-ChIP_MESCs_Mouse2.27377220
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.26829491
26GBX2_23144817_ChIP-Seq_PC3_Human2.23757893
27FUS_26573619_Chip-Seq_HEK293_Human2.21684713
28IGF1R_20145208_ChIP-Seq_DFB_Human2.18739382
29IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.18225068
30ZFP57_27257070_Chip-Seq_ESCs_Mouse2.18030745
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17236888
32NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16078605
33EWS_26573619_Chip-Seq_HEK293_Human2.15773746
34FOXP3_21729870_ChIP-Seq_TREG_Human2.12443129
35MYC_19079543_ChIP-ChIP_MESCs_Mouse2.10025499
36HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.09642828
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.05359029
38NOTCH1_21737748_ChIP-Seq_TLL_Human2.01350583
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.98997366
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.98242526
41DCP1A_22483619_ChIP-Seq_HELA_Human1.97492725
42SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.95909985
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.94219860
44ELK1_19687146_ChIP-ChIP_HELA_Human1.93464275
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.91893344
46SRF_21415370_ChIP-Seq_HL-1_Mouse1.89107995
47TAF15_26573619_Chip-Seq_HEK293_Human1.83894464
48E2F1_18555785_ChIP-Seq_MESCs_Mouse1.82819132
49MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.81518825
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.80282278
51P300_19829295_ChIP-Seq_ESCs_Human1.78893706
52GABP_19822575_ChIP-Seq_HepG2_Human1.78802570
53MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.78686267
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.78441353
55ER_23166858_ChIP-Seq_MCF-7_Human1.78354813
56IRF8_21731497_ChIP-ChIP_J774_Mouse1.77818410
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.75174405
58XRN2_22483619_ChIP-Seq_HELA_Human1.74764079
59EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.73936590
60POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.73647535
61MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73239596
62FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.72114391
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71887778
64CTBP2_25329375_ChIP-Seq_LNCAP_Human1.71295029
65IRF8_22096565_ChIP-ChIP_GC-B_Human1.67610393
66E2F1_21310950_ChIP-Seq_MCF-7_Human1.67173781
67CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65222885
68THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63810741
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.63660337
70CIITA_25753668_ChIP-Seq_RAJI_Human1.63558659
71ERG_20887958_ChIP-Seq_HPC-7_Mouse1.60429565
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59867329
73BP1_19119308_ChIP-ChIP_Hs578T_Human1.59866376
74KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.56604134
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.55028474
76SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.52170971
77CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.49849301
78PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.46733096
79TTF2_22483619_ChIP-Seq_HELA_Human1.46550965
80YY1_21170310_ChIP-Seq_MESCs_Mouse1.46159915
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.45696140
82CBP_20019798_ChIP-Seq_JUKART_Human1.45696140
83TP53_22573176_ChIP-Seq_HFKS_Human1.42628221
84PADI4_21655091_ChIP-ChIP_MCF-7_Human1.42552231
85ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.42367968
86NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41060379
87AR_21909140_ChIP-Seq_LNCAP_Human1.40153391
88KDM5A_27292631_Chip-Seq_BREAST_Human1.38743514
89SPI1_23547873_ChIP-Seq_NB4_Human1.38465194
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32317539
91NANOG_19829295_ChIP-Seq_ESCs_Human1.31938188
92SOX2_19829295_ChIP-Seq_ESCs_Human1.31938188
93EZH2_27294783_Chip-Seq_NPCs_Mouse1.31452274
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27691740
95ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.25428015
96SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25379720
97EZH2_22144423_ChIP-Seq_EOC_Human1.24040346
98MYC_18940864_ChIP-ChIP_HL60_Human1.22271821
99GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21788617
100IRF1_19129219_ChIP-ChIP_H3396_Human1.21634641
101FOXA1_25329375_ChIP-Seq_VCAP_Human1.21019201
102FOXA1_27270436_Chip-Seq_PROSTATE_Human1.21019201
103NFE2_27457419_Chip-Seq_LIVER_Mouse1.20654548
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.19237061
105TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17799588
106POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17799588
107PCGF2_27294783_Chip-Seq_NPCs_Mouse1.17249004
108ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.16988481
109FOXA1_21572438_ChIP-Seq_LNCaP_Human1.16282774
110STAT4_19710469_ChIP-ChIP_TH1__Mouse1.15950381
111MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.15789886
112BCAT_22108803_ChIP-Seq_LS180_Human1.15093136
113POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14863833
114KLF5_20875108_ChIP-Seq_MESCs_Mouse1.14141751
115TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13499793
116CRX_20693478_ChIP-Seq_RETINA_Mouse1.13291636
117FLI1_27457419_Chip-Seq_LIVER_Mouse1.13138031
118SMAD4_21799915_ChIP-Seq_A2780_Human1.13010300
119AR_20517297_ChIP-Seq_VCAP_Human1.12630566
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.12364304
121SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12247975
122STAT3_23295773_ChIP-Seq_U87_Human1.10752738
123AR_25329375_ChIP-Seq_VCAP_Human1.10209606
124E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08085861
125PIAS1_25552417_ChIP-Seq_VCAP_Human1.07740243
126ZFX_18555785_ChIP-Seq_MESCs_Mouse1.07727276
127OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07464841
128FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.07245324
129TCF4_22108803_ChIP-Seq_LS180_Human1.06544357
130RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06437513
131TFEB_21752829_ChIP-Seq_HELA_Human1.05938300
132TCF4_23295773_ChIP-Seq_U87_Human1.05859236
133NANOG_18555785_Chip-Seq_ESCs_Mouse1.04713722
134CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.02300843
135EGR1_19374776_ChIP-ChIP_THP-1_Human1.02255026
136EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02121724
137CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.01983197
138CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.01613279
139EGR1_23403033_ChIP-Seq_LIVER_Mouse1.01483519
140FLI1_21867929_ChIP-Seq_TH2_Mouse1.00964624
141P53_22387025_ChIP-Seq_ESCs_Mouse1.00273974
142HTT_18923047_ChIP-ChIP_STHdh_Human1.00135351
143TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00110058
144EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00018123
145SCL_19346495_ChIP-Seq_HPC-7_Human0.99215501
146POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96765756
147RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96174856
148SMAD3_21741376_ChIP-Seq_EPCs_Human0.96101555
149TP63_19390658_ChIP-ChIP_HaCaT_Human0.96018658
150STAT3_18555785_Chip-Seq_ESCs_Mouse0.95918887
151NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95405339
152MYB_26560356_Chip-Seq_TH2_Human0.92987153
153MYB_26560356_Chip-Seq_TH1_Human0.92946863
154PCGF2_27294783_Chip-Seq_ESCs_Mouse0.91569947
155IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.88357322
156STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.86842168
157TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.83569266
158CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83326775
159CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.82955388
160MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.82658611
161BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.80616747
162SOX2_18555785_ChIP-Seq_MESCs_Mouse0.79219552
163FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78754242
164SALL1_21062744_ChIP-ChIP_HESCs_Human0.75676691
165KAP1_22055183_ChIP-Seq_ESCs_Mouse0.74989927
166GATA3_26560356_Chip-Seq_TH2_Human0.74698479
167CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.74003234

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.64188491
2MP0008057_abnormal_DNA_replication4.11859963
3MP0010094_abnormal_chromosome_stability3.95595444
4MP0008877_abnormal_DNA_methylation3.31315534
5MP0003077_abnormal_cell_cycle3.30085920
6MP0008058_abnormal_DNA_repair3.24464310
7MP0003111_abnormal_nucleus_morphology3.19130789
8MP0004957_abnormal_blastocyst_morpholog2.95290506
9MP0003195_calcinosis2.89072665
10MP0005671_abnormal_response_to2.67719859
11MP0002396_abnormal_hematopoietic_system2.64620927
12MP0000569_abnormal_digit_pigmentation2.61051677
13MP0003763_abnormal_thymus_physiology2.57982784
14MP0008007_abnormal_cellular_replicative2.51880025
15MP0001835_abnormal_antigen_presentation2.50503486
16MP0003787_abnormal_imprinting2.48055324
17MP0003718_maternal_effect2.30866263
18MP0003880_abnormal_central_pattern2.00362904
19MP0006292_abnormal_olfactory_placode1.99544791
20MP0006072_abnormal_retinal_apoptosis1.98116102
21MP0005084_abnormal_gallbladder_morpholo1.93406945
22MP0003011_delayed_dark_adaptation1.92129550
23MP0005551_abnormal_eye_electrophysiolog1.91995964
24MP0008932_abnormal_embryonic_tissue1.83899609
25MP0002398_abnormal_bone_marrow1.80638021
26MP0005645_abnormal_hypothalamus_physiol1.77200448
27MP0005253_abnormal_eye_physiology1.76608864
28MP0003786_premature_aging1.76418044
29MP0003646_muscle_fatigue1.74053366
30MP0004142_abnormal_muscle_tone1.71206653
31MP0008872_abnormal_physiological_respon1.70874059
32MP0009785_altered_susceptibility_to1.70627864
33MP0001800_abnormal_humoral_immune1.68819492
34MP0009697_abnormal_copulation1.66533038
35MP0005075_abnormal_melanosome_morpholog1.65222045
36MP0000689_abnormal_spleen_morphology1.57148089
37MP0002876_abnormal_thyroid_physiology1.55658353
38MP0004381_abnormal_hair_follicle1.55543027
39MP0002837_dystrophic_cardiac_calcinosis1.54748652
40MP0009333_abnormal_splenocyte_physiolog1.53593588
41MP0002723_abnormal_immune_serum1.53042231
42MP0000685_abnormal_immune_system1.52705385
43MP0002420_abnormal_adaptive_immunity1.51446885
44MP0000703_abnormal_thymus_morphology1.50716425
45MP0002452_abnormal_antigen_presenting1.50002837
46MP0002210_abnormal_sex_determination1.49648852
47MP0001764_abnormal_homeostasis1.48842226
48MP0002638_abnormal_pupillary_reflex1.48407241
49MP0001819_abnormal_immune_cell1.48268568
50MP0001984_abnormal_olfaction1.47816176
51MP0009745_abnormal_behavioral_response1.47743412
52MP0003136_yellow_coat_color1.46645736
53MP0000716_abnormal_immune_system1.46361216
54MP0009046_muscle_twitch1.45708264
55MP0002163_abnormal_gland_morphology1.45520224
56MP0005397_hematopoietic_system_phenotyp1.44797847
57MP0001545_abnormal_hematopoietic_system1.44797847
58MP0002722_abnormal_immune_system1.44641110
59MP0000350_abnormal_cell_proliferation1.44083197
60MP0001188_hyperpigmentation1.43784406
61MP0000490_abnormal_crypts_of1.43102213
62MP0004808_abnormal_hematopoietic_stem1.41683657
63MP0006036_abnormal_mitochondrial_physio1.41535609
64MP0008875_abnormal_xenobiotic_pharmacok1.40269049
65MP0001968_abnormal_touch/_nociception1.39786409
66MP0010307_abnormal_tumor_latency1.38896488
67MP0001929_abnormal_gametogenesis1.38674003
68MP0008789_abnormal_olfactory_epithelium1.37289963
69MP0002429_abnormal_blood_cell1.36627036
70MP0005000_abnormal_immune_tolerance1.36578325
71MP0002166_altered_tumor_susceptibility1.34530930
72MP0001986_abnormal_taste_sensitivity1.34053101
73MP0005379_endocrine/exocrine_gland_phen1.32823314
74MP0002736_abnormal_nociception_after1.32765008
75MP0001790_abnormal_immune_system1.31513573
76MP0005387_immune_system_phenotype1.31513573
77MP0002019_abnormal_tumor_incidence1.28704051
78MP0002272_abnormal_nervous_system1.26252982
79MP0001119_abnormal_female_reproductive1.25847014
80MP0000427_abnormal_hair_cycle1.25683671
81MP0000653_abnormal_sex_gland1.24165210
82MP0000631_abnormal_neuroendocrine_gland1.23749093
83MP0001145_abnormal_male_reproductive1.23606043
84MP0002006_tumorigenesis1.23248633
85MP0001486_abnormal_startle_reflex1.22607801
86MP0006035_abnormal_mitochondrial_morpho1.22409540
87MP0004147_increased_porphyrin_level1.22102450
88MP0005025_abnormal_response_to1.19012455
89MP0004043_abnormal_pH_regulation1.18897844
90MP0000647_abnormal_sebaceous_gland1.18375052
91MP0003436_decreased_susceptibility_to1.16130723
92MP0003656_abnormal_erythrocyte_physiolo1.14743918
93MP0002148_abnormal_hypersensitivity_rea1.14677130
94MP0001905_abnormal_dopamine_level1.14638757
95MP0002938_white_spotting1.14013999
96MP0001293_anophthalmia1.11588958
97MP0003123_paternal_imprinting1.11252756
98MP0005174_abnormal_tail_pigmentation1.10298454
99MP0002928_abnormal_bile_duct1.09474038
100MP0001730_embryonic_growth_arrest1.07661953
101MP0005464_abnormal_platelet_physiology1.07065313
102MP0001485_abnormal_pinna_reflex1.06196960
103MP0000313_abnormal_cell_death1.06145939
104MP0005389_reproductive_system_phenotype1.05460669
105MP0002009_preneoplasia1.04606177
106MP0000015_abnormal_ear_pigmentation1.04531167
107MP0008995_early_reproductive_senescence1.03200011
108MP0002419_abnormal_innate_immunity1.02345055
109MP0002095_abnormal_skin_pigmentation1.01995445
110MP0006082_CNS_inflammation1.01358365
111MP0002653_abnormal_ependyma_morphology0.98880322
112MP0006276_abnormal_autonomic_nervous0.98317449
113MP0003806_abnormal_nucleotide_metabolis0.96534774
114MP0002572_abnormal_emotion/affect_behav0.95223602
115MP0002751_abnormal_autonomic_nervous0.92630283
116MP0003121_genomic_imprinting0.92393336
117MP0000372_irregular_coat_pigmentation0.91872455
118MP0002132_abnormal_respiratory_system0.91151721
119MP0003943_abnormal_hepatobiliary_system0.91018610
120MP0004885_abnormal_endolymph0.90808329
121MP0005394_taste/olfaction_phenotype0.90581635
122MP0005499_abnormal_olfactory_system0.90581635
123MP0009379_abnormal_foot_pigmentation0.90044801
124MP0001853_heart_inflammation0.89747627
125MP0004133_heterotaxia0.89091641
126MP0002277_abnormal_respiratory_mucosa0.88680321
127MP0003698_abnormal_male_reproductive0.88635390
128MP0002735_abnormal_chemical_nociception0.87067341
129MP0003724_increased_susceptibility_to0.85989380
130MP0002405_respiratory_system_inflammati0.85773202
131MP0002064_seizures0.85627032
132MP0001501_abnormal_sleep_pattern0.84529158
133MP0005646_abnormal_pituitary_gland0.84431291
134MP0002102_abnormal_ear_morphology0.84426062
135MP0004215_abnormal_myocardial_fiber0.83856945
136MP0003186_abnormal_redox_activity0.82423430
137MP0001919_abnormal_reproductive_system0.82364124
138MP0001346_abnormal_lacrimal_gland0.82130147
139MP0010155_abnormal_intestine_physiology0.81803665
140MP0005408_hypopigmentation0.80968200
141MP0005409_darkened_coat_color0.79867578
142MP0002160_abnormal_reproductive_system0.79500482
143MP0005395_other_phenotype0.79284847
144MP0003191_abnormal_cellular_cholesterol0.78833672
145MP0002557_abnormal_social/conspecific_i0.77651544
146MP0006054_spinal_hemorrhage0.77437857
147MP0002229_neurodegeneration0.76790460
148MP0009764_decreased_sensitivity_to0.76703651
149MP0004134_abnormal_chest_morphology0.75054954
150MP0004145_abnormal_muscle_electrophysio0.74919466
151MP0002234_abnormal_pharynx_morphology0.73980625
152MP0001529_abnormal_vocalization0.73389084
153MP0005410_abnormal_fertilization0.73184025
154MP0005391_vision/eye_phenotype0.72933020
155MP0005195_abnormal_posterior_eye0.72427489
156MP0005171_absent_coat_pigmentation0.72328233
157MP0001697_abnormal_embryo_size0.71958510
158MP0003699_abnormal_female_reproductive0.71555388
159MP0005266_abnormal_metabolism0.71471222
160MP0002080_prenatal_lethality0.71290967
161MP0002067_abnormal_sensory_capabilities0.70795424
162MP0002138_abnormal_hepatobiliary_system0.70545861

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.40184280
2Abnormality of midbrain morphology (HP:0002418)3.71990904
3Molar tooth sign on MRI (HP:0002419)3.71990904
4True hermaphroditism (HP:0010459)3.52205430
5Aplastic anemia (HP:0001915)3.34587218
6Breast hypoplasia (HP:0003187)3.26068887
7Methylmalonic acidemia (HP:0002912)3.17147554
8Acute necrotizing encephalopathy (HP:0006965)3.14197784
9Agnosia (HP:0010524)3.11787318
10Chromsome breakage (HP:0040012)3.03301778
11Abnormality of chromosome stability (HP:0003220)3.02676917
12Decreased central vision (HP:0007663)3.01969245
13Acute encephalopathy (HP:0006846)2.85218644
14Progressive macrocephaly (HP:0004481)2.82075381
15Stomatitis (HP:0010280)2.80830149
16Carpal bone hypoplasia (HP:0001498)2.80820626
17Type II lissencephaly (HP:0007260)2.79906875
18Congenital stationary night blindness (HP:0007642)2.76518052
19Abnormal number of erythroid precursors (HP:0012131)2.76347712
20Medial flaring of the eyebrow (HP:0010747)2.74632797
21Abnormal spermatogenesis (HP:0008669)2.73538159
22IgG deficiency (HP:0004315)2.73464968
23Nephronophthisis (HP:0000090)2.73369638
24Abnormal mitochondria in muscle tissue (HP:0008316)2.73218334
25Microvesicular hepatic steatosis (HP:0001414)2.72191880
26Increased CSF lactate (HP:0002490)2.72002689
27Mitochondrial inheritance (HP:0001427)2.71993873
28Attenuation of retinal blood vessels (HP:0007843)2.68780578
29Abolished electroretinogram (ERG) (HP:0000550)2.66242755
30Chromosomal breakage induced by crosslinking agents (HP:0003221)2.66108764
31Methylmalonic aciduria (HP:0012120)2.65160308
32Abnormality of cells of the erythroid lineage (HP:0012130)2.63012844
33Cerebral hypomyelination (HP:0006808)2.62860890
34Abnormality of the preputium (HP:0100587)2.60679560
35Chronic hepatic failure (HP:0100626)2.58044060
36IgM deficiency (HP:0002850)2.56320727
37Patellar aplasia (HP:0006443)2.55957430
38Colon cancer (HP:0003003)2.54039564
39T lymphocytopenia (HP:0005403)2.53543338
40Myelodysplasia (HP:0002863)2.50845873
41Absent rod-and cone-mediated responses on ERG (HP:0007688)2.46314405
42Aplasia/Hypoplasia of the tibia (HP:0005772)2.46311750
43Abnormal rod and cone electroretinograms (HP:0008323)2.44813262
44Decreased activity of mitochondrial respiratory chain (HP:0008972)2.43360911
45Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.43360911
46Abnormality of T cell number (HP:0011839)2.41262668
473-Methylglutaconic aciduria (HP:0003535)2.40816259
48Chronic otitis media (HP:0000389)2.38570360
49Abnormality of aspartate family amino acid metabolism (HP:0010899)2.38310110
50Meckel diverticulum (HP:0002245)2.38189467
51Decreased electroretinogram (ERG) amplitude (HP:0000654)2.36965964
52Premature graying of hair (HP:0002216)2.36241946
53Focal motor seizures (HP:0011153)2.35623745
54Abnormality of the renal cortex (HP:0011035)2.33020198
55Aplasia/Hypoplasia of the patella (HP:0006498)2.32709852
56Lipid accumulation in hepatocytes (HP:0006561)2.32396453
57Supernumerary spleens (HP:0009799)2.32264037
58Short tibia (HP:0005736)2.30414847
59Type I transferrin isoform profile (HP:0003642)2.29967844
60Pendular nystagmus (HP:0012043)2.29193106
61Amaurosis fugax (HP:0100576)2.28734611
62Abnormality of the ileum (HP:0001549)2.28071051
63Type 2 muscle fiber atrophy (HP:0003554)2.28023907
64Hyperglycinemia (HP:0002154)2.27497843
65Pancreatic cysts (HP:0001737)2.27311261
66Respiratory difficulties (HP:0002880)2.27072348
67Recurrent bronchitis (HP:0002837)2.26972796
68Abnormality of T cells (HP:0002843)2.26952177
69Abnormality of the renal medulla (HP:0100957)2.26163770
70Pancreatic fibrosis (HP:0100732)2.24940628
71Petechiae (HP:0000967)2.24427653
72Lymphoma (HP:0002665)2.24266589
73Abnormality of the fingertips (HP:0001211)2.23566870
74Recurrent viral infections (HP:0004429)2.23296100
75Bone marrow hypocellularity (HP:0005528)2.22994660
76Abnormality of the anterior horn cell (HP:0006802)2.21792437
77Degeneration of anterior horn cells (HP:0002398)2.21792437
78Abnormality of the vitamin B12 metabolism (HP:0004341)2.19539194
79Cerebellar dysplasia (HP:0007033)2.19500033
80Abnormality of serum amino acid levels (HP:0003112)2.18636685
81Broad face (HP:0000283)2.18570208
82Abnormality of B cell number (HP:0010975)2.17817476
83B lymphocytopenia (HP:0010976)2.17817476
84Medulloblastoma (HP:0002885)2.15162710
85Abnormality of vitamin B metabolism (HP:0004340)2.15100764
86Optic disc pallor (HP:0000543)2.13822317
87Abnormal drinking behavior (HP:0030082)2.13717804
88Polydipsia (HP:0001959)2.13717804
89Febrile seizures (HP:0002373)2.13346227
90Hypothermia (HP:0002045)2.12332837
91Aplasia/Hypoplasia of the uvula (HP:0010293)2.11818226
92Aplasia/Hypoplasia of the tongue (HP:0010295)2.11464562
93Thrombocytosis (HP:0001894)2.11059842
94Stomach cancer (HP:0012126)2.10703150
95CNS hypomyelination (HP:0003429)2.10170891
96Abnormality of the labia minora (HP:0012880)2.09975015
97Abnormality of the heme biosynthetic pathway (HP:0010472)2.09498516
98Oral leukoplakia (HP:0002745)2.08476968
99Anencephaly (HP:0002323)2.08223588
100Nephrogenic diabetes insipidus (HP:0009806)2.08010997
101Abnormal lung lobation (HP:0002101)2.06679079
102Impulsivity (HP:0100710)2.05820241
103Renal cortical cysts (HP:0000803)2.04442091
104Bronchitis (HP:0012387)2.03531109
105Recurrent abscess formation (HP:0002722)2.02672906
106Muscle fiber atrophy (HP:0100295)2.02469774
107Hepatosplenomegaly (HP:0001433)2.01902433
108Increased corneal curvature (HP:0100692)2.01595023
109Keratoconus (HP:0000563)2.01595023
110Abnormality of T cell physiology (HP:0011840)2.00792033
111Capillary hemangiomas (HP:0005306)2.00174587
112Basal cell carcinoma (HP:0002671)2.00087341
113Sclerocornea (HP:0000647)1.99693584
114Parakeratosis (HP:0001036)1.99387751
115Sloping forehead (HP:0000340)1.96739345
116Absent thumb (HP:0009777)1.96690870
117Lissencephaly (HP:0001339)1.96091738
118Abnormality of macular pigmentation (HP:0008002)1.95544685
119Clubbing of toes (HP:0100760)1.95488273
120Congenital primary aphakia (HP:0007707)1.94700104
121Facial hemangioma (HP:0000329)1.94258444
122Encephalitis (HP:0002383)1.94234558
123Abnormality of the pons (HP:0007361)1.94115408
124Gaze-evoked nystagmus (HP:0000640)1.94035730
125Pulmonary fibrosis (HP:0002206)1.93716673
126Duodenal stenosis (HP:0100867)1.93278910
127Small intestinal stenosis (HP:0012848)1.93278910
128Large for gestational age (HP:0001520)1.92697593
129Gait imbalance (HP:0002141)1.91571841
130Rough bone trabeculation (HP:0100670)1.90705612
131Reticulocytopenia (HP:0001896)1.90626325
132Lactic acidosis (HP:0003128)1.89795566
133Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.89720248
134Hepatocellular necrosis (HP:0001404)1.89383232
135Homocystinuria (HP:0002156)1.88371778
136Abnormality of homocysteine metabolism (HP:0010919)1.88371778
137Abnormality of the columella (HP:0009929)1.87417005
138Panhypogammaglobulinemia (HP:0003139)1.87148446
139Hypoplasia of the pons (HP:0012110)1.86535304
140Severe combined immunodeficiency (HP:0004430)1.86406562
141Progressive inability to walk (HP:0002505)1.85846454
142Thyroiditis (HP:0100646)1.84908608
143Dialeptic seizures (HP:0011146)1.84703718
144Increased serum lactate (HP:0002151)1.84643075
145Postaxial foot polydactyly (HP:0001830)1.84445488
146Inability to walk (HP:0002540)1.84359013
147Azoospermia (HP:0000027)1.84269771
148Hepatic necrosis (HP:0002605)1.84067940
149Cellular immunodeficiency (HP:0005374)1.83951899
150Agammaglobulinemia (HP:0004432)1.82381966
151Cerebral edema (HP:0002181)1.82365818
152Pancytopenia (HP:0001876)1.82180421
153Increased hepatocellular lipid droplets (HP:0006565)1.81510314
15411 pairs of ribs (HP:0000878)1.81203747
155Macrocytic anemia (HP:0001972)1.81032726
156Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.80992183
157Abnormality of alanine metabolism (HP:0010916)1.80992183
158Hyperalaninemia (HP:0003348)1.80992183
159Retinal dysplasia (HP:0007973)1.80769074
160Irregular epiphyses (HP:0010582)1.80063405
161Rhabdomyosarcoma (HP:0002859)1.79303348
162Recurrent bacterial skin infections (HP:0005406)1.77951643
163Combined immunodeficiency (HP:0005387)1.77279551
164Cystic liver disease (HP:0006706)1.77057183
165Lymphopenia (HP:0001888)1.76494332
166Pallor (HP:0000980)1.76008148
167Congenital hepatic fibrosis (HP:0002612)1.75331236
168Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.75301005
169Hypomagnesemia (HP:0002917)1.74756522
170Exertional dyspnea (HP:0002875)1.74739139
171Bile duct proliferation (HP:0001408)1.74221914
172Abnormal biliary tract physiology (HP:0012439)1.74221914
173Median cleft lip (HP:0000161)1.73535462
174Male pseudohermaphroditism (HP:0000037)1.73300183
175Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.72690769
176Lethargy (HP:0001254)1.72331671
177Optic nerve hypoplasia (HP:0000609)1.72269375
178Abnormality of the femoral head (HP:0003368)1.72139450
179Abnormality of glycine metabolism (HP:0010895)1.68608817
180Abnormality of serine family amino acid metabolism (HP:0010894)1.68608817
181Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67492980
182Abnormal protein N-linked glycosylation (HP:0012347)1.67492980
183Abnormal protein glycosylation (HP:0012346)1.67492980
184Abnormal glycosylation (HP:0012345)1.67492980

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K23.75854722
2FRK3.69080824
3WEE13.47003987
4BUB13.24984111
5CDC72.91932094
6EIF2AK12.80678224
7WNK32.74766916
8PLK42.62529423
9TRIM282.56917272
10BMPR1B2.35628423
11PINK12.26772396
12EIF2AK32.24798357
13STK162.22417285
14SRPK12.15469544
15TXK2.11819762
16ADRBK22.08209289
17NME21.99951365
18VRK11.92034360
19MST41.91464259
20MAP3K61.87359407
21STK101.86644517
22MKNK21.80037076
23PIM21.79846509
24TEC1.75996757
25BRSK21.72336741
26CDK81.71675093
27IRAK41.66880144
28MAP3K141.61322738
29TSSK61.59297861
30MKNK11.55064563
31ACVR1B1.54776438
32PLK11.54037821
33GRK11.50994064
34FLT31.47935470
35TTK1.46606994
36WNK41.43216579
37ARAF1.41256351
38BCR1.39858649
39PLK31.38774131
40ZAK1.38194464
41IKBKE1.38036995
42OXSR11.37987461
43ATR1.36753794
44BMPR21.35304549
45ZAP701.26677568
46MOS1.24536718
47EIF2AK21.24114863
48EPHA41.23381379
49PASK1.22263851
50NLK1.19226145
51STK391.17485739
52BRAF1.17126592
53TAOK31.16624358
54CHEK21.15070011
55CAMKK21.14119660
56CDK71.12618530
57INSRR1.12531285
58MAP4K11.11277412
59MAPK131.11189208
60JAK31.11144943
61IKBKB1.10258029
62GRK71.10064962
63ERBB31.08765596
64AURKB1.07302441
65KIT1.06034217
66NEK21.02344928
67MAP3K41.00286070
68DYRK30.99440419
69PLK20.97514502
70MUSK0.97263370
71STK40.95467847
72DAPK20.94507785
73TGFBR20.93529525
74RPS6KA50.92597879
75CASK0.90743209
76TYK20.90264433
77CSNK1G10.90192401
78PBK0.89599245
79MELK0.86331353
80MAP2K70.86261211
81BTK0.84727528
82VRK20.83591619
83PIM10.83533899
84AURKA0.83410209
85CHEK10.82508152
86ATM0.82252079
87CSNK1G20.80441478
88MAP3K130.80360699
89CSNK1G30.79042929
90RPS6KA40.78996151
91NTRK30.78206106
92BCKDK0.76373264
93MARK30.76082021
94MAP2K30.75956666
95PRKCQ0.75167199
96MINK10.73966025
97CHUK0.73719626
98TNIK0.72065304
99TESK20.71601924
100NEK60.71156651
101IRAK10.71112335
102TNK20.70342246
103NEK10.69602558
104STK240.68954233
105ADRBK10.67264198
106CSNK1A1L0.67122594
107CSNK2A10.66825085
108CDK40.66762617
109PAK30.66172196
110CLK10.64180377
111NME10.63916003
112RAF10.63852862
113TIE10.62495487
114OBSCN0.62013981
115CDK90.61686427
116AKT30.61573173
117CSNK2A20.60908352
118MAP2K60.60868951
119EPHA30.58663679
120SIK30.56846768
121NUAK10.56003872
122PRKCG0.55983917
123BRSK10.55768984
124TBK10.55119624
125PRKCE0.54960039
126LCK0.54379299
127ITK0.54075619
128PNCK0.53476246
129MAP3K120.52229913
130IRAK30.51156657
131LYN0.50111797
132TGFBR10.49995650
133DYRK20.49292962
134CDK20.48488238
135RPS6KB20.47499863
136CCNB10.47126288
137PIK3CA0.46742747
138MAPKAPK50.45019174
139CDK30.44054182
140MAPK150.44014096
141MAP3K80.43966248
142BRD40.43203507
143RPS6KB10.42400687
144CAMK2A0.42083960
145SYK0.41003854
146TLK10.40694070
147MAPKAPK30.40140171
148PKN10.39520303
149NTRK20.39208572
150CSNK1A10.35892842
151SIK20.33742399
152PRKACA0.32772496
153FES0.32325174

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.79584239
2RNA polymerase_Homo sapiens_hsa030203.61509628
3Proteasome_Homo sapiens_hsa030503.43650804
4Mismatch repair_Homo sapiens_hsa034303.43264727
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.30090675
6Homologous recombination_Homo sapiens_hsa034403.10428979
7Non-homologous end-joining_Homo sapiens_hsa034502.80806691
8Basal transcription factors_Homo sapiens_hsa030222.78184786
9Protein export_Homo sapiens_hsa030602.65039805
10Spliceosome_Homo sapiens_hsa030402.62920882
11Ribosome_Homo sapiens_hsa030102.60919917
12Nucleotide excision repair_Homo sapiens_hsa034202.48093519
13Pyrimidine metabolism_Homo sapiens_hsa002402.46956633
14Phototransduction_Homo sapiens_hsa047442.45590457
15Base excision repair_Homo sapiens_hsa034102.38681150
16Fanconi anemia pathway_Homo sapiens_hsa034602.34856479
17Cell cycle_Homo sapiens_hsa041102.30673971
18RNA transport_Homo sapiens_hsa030132.29592611
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.22574254
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.14445891
21RNA degradation_Homo sapiens_hsa030182.12479547
22Butanoate metabolism_Homo sapiens_hsa006501.81813455
23Propanoate metabolism_Homo sapiens_hsa006401.75700159
24Nitrogen metabolism_Homo sapiens_hsa009101.73610504
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.73128406
26Primary immunodeficiency_Homo sapiens_hsa053401.68310893
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64406184
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.61148746
29One carbon pool by folate_Homo sapiens_hsa006701.60093272
30p53 signaling pathway_Homo sapiens_hsa041151.49718949
31Purine metabolism_Homo sapiens_hsa002301.45685811
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.44741290
33Caffeine metabolism_Homo sapiens_hsa002321.44718130
34Folate biosynthesis_Homo sapiens_hsa007901.43527727
35Antigen processing and presentation_Homo sapiens_hsa046121.40534707
36Epstein-Barr virus infection_Homo sapiens_hsa051691.38706858
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37081687
38Intestinal immune network for IgA production_Homo sapiens_hsa046721.31998244
39Peroxisome_Homo sapiens_hsa041461.30520782
40Alzheimers disease_Homo sapiens_hsa050101.30032936
41Vitamin B6 metabolism_Homo sapiens_hsa007501.26236230
42Allograft rejection_Homo sapiens_hsa053301.25944268
43Olfactory transduction_Homo sapiens_hsa047401.23867237
44mRNA surveillance pathway_Homo sapiens_hsa030151.23039406
45Herpes simplex infection_Homo sapiens_hsa051681.21514771
46Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.17776153
47Nicotine addiction_Homo sapiens_hsa050331.15733287
48Other glycan degradation_Homo sapiens_hsa005111.13596932
49NF-kappa B signaling pathway_Homo sapiens_hsa040641.12603334
50RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.08810006
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08692254
52Tryptophan metabolism_Homo sapiens_hsa003801.04301254
53NOD-like receptor signaling pathway_Homo sapiens_hsa046211.02294806
54Collecting duct acid secretion_Homo sapiens_hsa049661.02266085
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.00776270
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.99238701
57Autoimmune thyroid disease_Homo sapiens_hsa053200.91672203
58Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.90721673
59Chemical carcinogenesis_Homo sapiens_hsa052040.83460551
60Circadian rhythm_Homo sapiens_hsa047100.82869915
61Measles_Homo sapiens_hsa051620.82844606
62Hematopoietic cell lineage_Homo sapiens_hsa046400.80578515
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.79161671
64Rheumatoid arthritis_Homo sapiens_hsa053230.77898808
65Retinol metabolism_Homo sapiens_hsa008300.75632175
66Regulation of autophagy_Homo sapiens_hsa041400.75484547
67Asthma_Homo sapiens_hsa053100.73444366
68Cardiac muscle contraction_Homo sapiens_hsa042600.71392121
69Taste transduction_Homo sapiens_hsa047420.70205261
70Graft-versus-host disease_Homo sapiens_hsa053320.69699111
71Legionellosis_Homo sapiens_hsa051340.68357700
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.67648441
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65759637
74Viral carcinogenesis_Homo sapiens_hsa052030.65347251
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65039859
76Morphine addiction_Homo sapiens_hsa050320.64969536
77Steroid hormone biosynthesis_Homo sapiens_hsa001400.63792143
78Sphingolipid metabolism_Homo sapiens_hsa006000.62640375
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.61870388
80Primary bile acid biosynthesis_Homo sapiens_hsa001200.60126047
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60003686
82Sulfur relay system_Homo sapiens_hsa041220.59728297
83Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59664348
84Systemic lupus erythematosus_Homo sapiens_hsa053220.59042836
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58130309
86Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.55234431
87Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52917066
88T cell receptor signaling pathway_Homo sapiens_hsa046600.52239319
89HTLV-I infection_Homo sapiens_hsa051660.52072275
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52060585
91Shigellosis_Homo sapiens_hsa051310.50629058
92Influenza A_Homo sapiens_hsa051640.50221846
93SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49147488
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48977874
95GABAergic synapse_Homo sapiens_hsa047270.48411628
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48147441
97Leishmaniasis_Homo sapiens_hsa051400.47983308
98N-Glycan biosynthesis_Homo sapiens_hsa005100.46978679
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46115411
100Apoptosis_Homo sapiens_hsa042100.45321705
101Jak-STAT signaling pathway_Homo sapiens_hsa046300.42696367
102Linoleic acid metabolism_Homo sapiens_hsa005910.42574410
103Salivary secretion_Homo sapiens_hsa049700.41728437
104Huntingtons disease_Homo sapiens_hsa050160.41704904
105Steroid biosynthesis_Homo sapiens_hsa001000.41476476
106Oocyte meiosis_Homo sapiens_hsa041140.41003047
107Sulfur metabolism_Homo sapiens_hsa009200.40947305
108B cell receptor signaling pathway_Homo sapiens_hsa046620.40643132
109Hepatitis B_Homo sapiens_hsa051610.40405439
110beta-Alanine metabolism_Homo sapiens_hsa004100.39630658
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.39576420
112Drug metabolism - other enzymes_Homo sapiens_hsa009830.39430653
113Ether lipid metabolism_Homo sapiens_hsa005650.39026158
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.38769197
115Thyroid cancer_Homo sapiens_hsa052160.38368308
116Circadian entrainment_Homo sapiens_hsa047130.37369892
117Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36296126
118Pentose phosphate pathway_Homo sapiens_hsa000300.35236660
119Serotonergic synapse_Homo sapiens_hsa047260.34678597
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34282849
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33992445
122ABC transporters_Homo sapiens_hsa020100.31794043
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.31768038
124Type I diabetes mellitus_Homo sapiens_hsa049400.30817208
125Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.29137361
126Arachidonic acid metabolism_Homo sapiens_hsa005900.27926998
127Glutathione metabolism_Homo sapiens_hsa004800.24352081
128Parkinsons disease_Homo sapiens_hsa050120.24222025
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.23586400
130Metabolic pathways_Homo sapiens_hsa011000.23031216
131alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22449065
132Hepatitis C_Homo sapiens_hsa051600.20765485
133Toxoplasmosis_Homo sapiens_hsa051450.20760847
134Malaria_Homo sapiens_hsa051440.19527367
135Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.19032352
136Fatty acid elongation_Homo sapiens_hsa000620.17583584
137Oxidative phosphorylation_Homo sapiens_hsa001900.15483899
138TNF signaling pathway_Homo sapiens_hsa046680.12422613
139MicroRNAs in cancer_Homo sapiens_hsa052060.12028001
140Selenocompound metabolism_Homo sapiens_hsa004500.10924230

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »