RBM6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of phosphoprotein phosphatase activity (GO:0032516)6.15192213
2negative regulation of mast cell activation (GO:0033004)5.29374699
3nuclear pore complex assembly (GO:0051292)5.19368789
4regulation of activation of Janus kinase activity (GO:0010533)4.83852744
5nuclear pore organization (GO:0006999)4.83608024
6mitotic sister chromatid cohesion (GO:0007064)4.58796611
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.29455309
8pore complex assembly (GO:0046931)4.22670237
9regulation of B cell receptor signaling pathway (GO:0050855)4.19721408
10kinetochore organization (GO:0051383)4.16947716
11histone H3-K9 methylation (GO:0051567)3.86851470
12monoubiquitinated protein deubiquitination (GO:0035520)3.81106218
13regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.78416625
14meiotic chromosome segregation (GO:0045132)3.69609225
15mitotic chromosome condensation (GO:0007076)3.68348403
16negative regulation of DNA-dependent DNA replication (GO:2000104)3.67499067
17pyrimidine nucleobase catabolic process (GO:0006208)3.65262918
18negative regulation of phagocytosis (GO:0050765)3.62957975
19regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.61395775
20response to pheromone (GO:0019236)3.61224186
21regulation of DNA endoreduplication (GO:0032875)3.60869433
22kinetochore assembly (GO:0051382)3.59948241
23histone H3-K36 demethylation (GO:0070544)3.59917172
24mitotic metaphase plate congression (GO:0007080)3.59910566
25peptidyl-lysine trimethylation (GO:0018023)3.53393192
26axoneme assembly (GO:0035082)3.46556130
27sister chromatid cohesion (GO:0007062)3.43408100
28activated T cell proliferation (GO:0050798)3.40945418
29histone H3-K9 modification (GO:0061647)3.38528366
30metaphase plate congression (GO:0051310)3.34163923
31positive regulation of phosphatase activity (GO:0010922)3.28782525
32neural tube formation (GO:0001841)3.26568309
33histone H3-K4 trimethylation (GO:0080182)3.25693133
34regulation of helicase activity (GO:0051095)3.24877106
35regulation of RNA export from nucleus (GO:0046831)3.13139389
36establishment of protein localization to Golgi (GO:0072600)3.12637671
37intra-S DNA damage checkpoint (GO:0031573)3.10837952
38presynaptic membrane assembly (GO:0097105)3.10372268
39DNA topological change (GO:0006265)3.09807393
40nucleobase catabolic process (GO:0046113)3.08681392
41histone H3-K4 methylation (GO:0051568)3.03606076
42interkinetic nuclear migration (GO:0022027)3.01695814
43positive regulation of mitotic sister chromatid separation (GO:1901970)3.01643593
44positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.01643593
45positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.01643593
46negative regulation of B cell proliferation (GO:0030889)3.01034433
47regulation of histone H3-K9 methylation (GO:0051570)2.98939551
48negative regulation of histone methylation (GO:0031061)2.98844608
49microtubule depolymerization (GO:0007019)2.98454594
50negative regulation of cytosolic calcium ion concentration (GO:0051481)2.98100173
51sister chromatid segregation (GO:0000819)2.97536653
52negative regulation of protein oligomerization (GO:0032460)2.95842383
53DNA replication-independent nucleosome organization (GO:0034724)2.95444419
54DNA replication-independent nucleosome assembly (GO:0006336)2.95444419
55mRNA splice site selection (GO:0006376)2.95173452
56fucose catabolic process (GO:0019317)2.94887618
57L-fucose metabolic process (GO:0042354)2.94887618
58L-fucose catabolic process (GO:0042355)2.94887618
59regulation of spindle organization (GO:0090224)2.93349112
60negative regulation of alpha-beta T cell activation (GO:0046636)2.92098244
61mitotic nuclear envelope disassembly (GO:0007077)2.90730166
62protein targeting to Golgi (GO:0000042)2.88667318
63regulation of nuclear cell cycle DNA replication (GO:0033262)2.88277219
64regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.86580952
65histone demethylation (GO:0016577)2.85959271
66histone lysine demethylation (GO:0070076)2.84919220
67negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.84879869
68negative regulation of translation, ncRNA-mediated (GO:0040033)2.84879869
69regulation of translation, ncRNA-mediated (GO:0045974)2.84879869
70epithelial cilium movement (GO:0003351)2.84617755
71establishment of chromosome localization (GO:0051303)2.84353648
72phosphatidylethanolamine metabolic process (GO:0046337)2.83914888
73cilium or flagellum-dependent cell motility (GO:0001539)2.80583990
74histone H2A acetylation (GO:0043968)2.78713818
75maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.78154423
76histone lysine methylation (GO:0034968)2.78122457
77positive regulation of glycolytic process (GO:0045821)2.77837692
78retrograde transport, vesicle recycling within Golgi (GO:0000301)2.77529262
79regulation of sister chromatid cohesion (GO:0007063)2.77316176
80regulation of memory T cell differentiation (GO:0043380)2.77266632
81protein localization to kinetochore (GO:0034501)2.77245198
82glial cell proliferation (GO:0014009)2.75590478
83pre-miRNA processing (GO:0031054)2.74228190
84peptidyl-lysine methylation (GO:0018022)2.72872393
85dosage compensation (GO:0007549)2.72200807
86spindle checkpoint (GO:0031577)2.70820534
87mitotic sister chromatid segregation (GO:0000070)2.70262271
88nuclear envelope disassembly (GO:0051081)2.69002019
89membrane disassembly (GO:0030397)2.69002019
90regulation of mitotic metaphase/anaphase transition (GO:0030071)2.66072946
91replication fork processing (GO:0031297)2.65898485
92presynaptic membrane organization (GO:0097090)2.65886661
93regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.64917090
94regulation of mitotic spindle checkpoint (GO:1903504)2.64917090
95reciprocal DNA recombination (GO:0035825)2.64737127
96reciprocal meiotic recombination (GO:0007131)2.64737127
97DNA geometric change (GO:0032392)2.64160496
98CENP-A containing nucleosome assembly (GO:0034080)2.63321726
99phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.63060808
100DNA double-strand break processing (GO:0000729)2.62949572
101limb bud formation (GO:0060174)2.62829448
102kidney morphogenesis (GO:0060993)2.62826152
103cellular response to ethanol (GO:0071361)2.62564178
104centriole replication (GO:0007099)2.61901103
105adaptation of signaling pathway (GO:0023058)2.61421553
106regulation of mitotic spindle organization (GO:0060236)2.61087910
107transepithelial transport (GO:0070633)2.60930036
108regulation of histone methylation (GO:0031060)2.60804014
109negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.60468296
110DNA duplex unwinding (GO:0032508)2.60079574
111protein K6-linked ubiquitination (GO:0085020)2.60064055
112positive regulation of gamma-delta T cell activation (GO:0046645)2.60049371
113regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.59717867
114DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.59665188
115V(D)J recombination (GO:0033151)2.59651299
116chromatin remodeling at centromere (GO:0031055)2.59474573
117attachment of spindle microtubules to kinetochore (GO:0008608)2.59392498
118regulation of sister chromatid segregation (GO:0033045)2.59020912
119regulation of mitotic sister chromatid separation (GO:0010965)2.59020912
120regulation of mitotic sister chromatid segregation (GO:0033047)2.59020912
121DNA strand renaturation (GO:0000733)2.58293966
122spindle assembly checkpoint (GO:0071173)2.58250808
123piRNA metabolic process (GO:0034587)2.57230365
124regulation of DNA damage checkpoint (GO:2000001)2.57031274
125cellular response to sterol (GO:0036315)2.56882418
126protein localization to chromosome, centromeric region (GO:0071459)2.56755552
127histone H3-K9 demethylation (GO:0033169)2.56128013
128negative thymic T cell selection (GO:0045060)2.56002390
129protein dealkylation (GO:0008214)2.55791858
130protein demethylation (GO:0006482)2.55791858
131negative T cell selection (GO:0043383)2.55105786
132chromatin assembly or disassembly (GO:0006333)2.54481398
133alternative mRNA splicing, via spliceosome (GO:0000380)2.53462947
134cilium movement (GO:0003341)2.53322161
135regulation of glucokinase activity (GO:0033131)2.53213780
136regulation of hexokinase activity (GO:1903299)2.53213780
137regulation of DNA-dependent DNA replication (GO:0090329)2.52912234
138positive regulation of granulocyte differentiation (GO:0030854)2.51623579
139DNA conformation change (GO:0071103)2.51084773
140DNA damage response, signal transduction resulting in transcription (GO:0042772)2.50461381
141regulation of chromosome segregation (GO:0051983)2.49995274
142mitotic spindle assembly checkpoint (GO:0007094)2.49789488
143histone mRNA catabolic process (GO:0071044)2.49637615
144mitotic spindle checkpoint (GO:0071174)2.49598646
145dendritic spine morphogenesis (GO:0060997)2.49348117
146negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.49043388
147negative regulation of sister chromatid segregation (GO:0033046)2.49043388
148negative regulation of mitotic sister chromatid separation (GO:2000816)2.49043388
149negative regulation of mitotic sister chromatid segregation (GO:0033048)2.49043388
150phosphatidylethanolamine biosynthetic process (GO:0006646)2.46649943
151regulation of protein glycosylation (GO:0060049)2.41496946
152DNA deamination (GO:0045006)2.40683802
153head development (GO:0060322)2.39281998
154positive regulation of defense response to virus by host (GO:0002230)2.38431151
155brain morphogenesis (GO:0048854)2.37615827
156protein localization to Golgi apparatus (GO:0034067)2.37337404
157auditory receptor cell differentiation (GO:0042491)2.35775692
158glycerophospholipid catabolic process (GO:0046475)2.35272864
159forebrain morphogenesis (GO:0048853)2.35051569
160proline transport (GO:0015824)2.34906184
161detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.31780079
162cellular response to interleukin-15 (GO:0071350)2.31477902
163cornea development in camera-type eye (GO:0061303)2.30173971
164sympathetic nervous system development (GO:0048485)2.30115585
165detection of light stimulus involved in sensory perception (GO:0050962)2.29325337
166detection of light stimulus involved in visual perception (GO:0050908)2.29325337
167regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.27801723
168regulation of T cell receptor signaling pathway (GO:0050856)2.27646234
169negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.26714119
170regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.25588055
171negative regulation of cell killing (GO:0031342)2.25428391
172negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.25428391
173DNA methylation involved in gamete generation (GO:0043046)2.21202908
174retinal cone cell development (GO:0046549)2.20819342
175interferon-gamma secretion (GO:0072643)2.20523811
176response to interleukin-15 (GO:0070672)2.20444027
177cilium morphogenesis (GO:0060271)2.20198335
178glycosphingolipid biosynthetic process (GO:0006688)2.19651851
179protein localization to cilium (GO:0061512)2.19508675
180cellular ketone body metabolic process (GO:0046950)2.19174764
181negative regulation of adaptive immune response (GO:0002820)2.18472861
182somite development (GO:0061053)2.17730023
183developmental pigmentation (GO:0048066)2.17727436
184negative regulation of B cell mediated immunity (GO:0002713)2.16768499
185negative regulation of immunoglobulin mediated immune response (GO:0002890)2.16768499
186positive regulation of developmental pigmentation (GO:0048087)2.16360791
187negative regulation of exocytosis (GO:0045920)2.16094735
188positive T cell selection (GO:0043368)2.15851494
189regulation of gamma-delta T cell activation (GO:0046643)2.14332501

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.70844551
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.73623949
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.11240773
4SALL1_21062744_ChIP-ChIP_HESCs_Human3.81779255
5KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.51129319
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.47740635
7ZNF274_21170338_ChIP-Seq_K562_Hela3.04673249
8GBX2_23144817_ChIP-Seq_PC3_Human2.94706567
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.92054463
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.80947184
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.62318238
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.54939435
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.35635856
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.29124466
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.26987110
16EZH2_22144423_ChIP-Seq_EOC_Human2.11335078
17RBPJ_22232070_ChIP-Seq_NCS_Mouse2.09703738
18VDR_22108803_ChIP-Seq_LS180_Human2.07599364
19YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.05134035
20STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.92569607
21AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.89878121
22PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.88022379
23SMAD_19615063_ChIP-ChIP_OVARY_Human1.83619368
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.83218087
25TAF15_26573619_Chip-Seq_HEK293_Human1.80468831
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.78346317
27ER_23166858_ChIP-Seq_MCF-7_Human1.78058301
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76749064
29CIITA_25753668_ChIP-Seq_RAJI_Human1.76370084
30BCAT_22108803_ChIP-Seq_LS180_Human1.71390204
31AR_21909140_ChIP-Seq_LNCAP_Human1.70484180
32* STAT3_23295773_ChIP-Seq_U87_Human1.67012787
33MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.64419002
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.64340602
35IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.62829277
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62663896
37P300_19829295_ChIP-Seq_ESCs_Human1.61645011
38* TCF4_23295773_ChIP-Seq_U87_Human1.61624810
39ELK1_19687146_ChIP-ChIP_HELA_Human1.60653924
40CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60064024
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.59384535
42SMAD4_21799915_ChIP-Seq_A2780_Human1.58688403
43ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.56373446
44MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.54779321
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.52886117
46CBP_20019798_ChIP-Seq_JUKART_Human1.51009851
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51009851
48EWS_26573619_Chip-Seq_HEK293_Human1.50319380
49NR3C1_21868756_ChIP-Seq_MCF10A_Human1.47149744
50RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44966007
51HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.44251974
52AR_25329375_ChIP-Seq_VCAP_Human1.41391687
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.39705602
54STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.39487610
55DROSHA_22980978_ChIP-Seq_HELA_Human1.38411002
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38296007
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37895767
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36099344
59AR_21572438_ChIP-Seq_LNCaP_Human1.34387024
60TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.34341409
61* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33603728
62TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33327984
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.33197814
64CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32920196
65ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32228755
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.31583670
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.31406458
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31248185
69MYC_22102868_ChIP-Seq_BL_Human1.30847762
70MYC_18555785_ChIP-Seq_MESCs_Mouse1.30765861
71RUNX2_22187159_ChIP-Seq_PCA_Human1.29702638
72* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.28991699
73FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.28704919
74PKCTHETA_26484144_Chip-Seq_BREAST_Human1.28208197
75PRDM14_20953172_ChIP-Seq_ESCs_Human1.27291124
76TCF4_22108803_ChIP-Seq_LS180_Human1.26289380
77SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25116503
78PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.24717367
79POU5F1_16153702_ChIP-ChIP_HESCs_Human1.24368782
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.23615306
81MYCN_18555785_ChIP-Seq_MESCs_Mouse1.21490095
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.21097962
83OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20780011
84* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.19194715
85* VDR_23849224_ChIP-Seq_CD4+_Human1.19074005
86PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18762379
87REST_21632747_ChIP-Seq_MESCs_Mouse1.18296888
88FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.16366004
89BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.15293444
90TOP2B_26459242_ChIP-Seq_MCF-7_Human1.15107824
91EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.15058925
92FUS_26573619_Chip-Seq_HEK293_Human1.13120250
93IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.12867478
94GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12252133
95FLI1_21867929_ChIP-Seq_TH2_Mouse1.12250090
96P53_22387025_ChIP-Seq_ESCs_Mouse1.10537389
97MYC_19030024_ChIP-ChIP_MESCs_Mouse1.09794618
98KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09438842
99MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08902693
100KDM5A_27292631_Chip-Seq_BREAST_Human1.08564203
101GATA1_22025678_ChIP-Seq_K562_Human1.08222066
102RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08216187
103NFE2_27457419_Chip-Seq_LIVER_Mouse1.07387510
104SOX2_21211035_ChIP-Seq_LN229_Gbm1.06698335
105GATA3_26560356_Chip-Seq_TH2_Human1.05215554
106TP53_16413492_ChIP-PET_HCT116_Human1.05049012
107KDM2B_26808549_Chip-Seq_REH_Human1.04855449
108GATA3_27048872_Chip-Seq_THYMUS_Human1.04173683
109* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03961886
110PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03508969
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01952109
112SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01326807
113MYB_26560356_Chip-Seq_TH1_Human1.00658683
114RNF2_27304074_Chip-Seq_NSC_Mouse0.99784496
115CBX2_27304074_Chip-Seq_ESCs_Mouse0.99725654
116BRD4_25478319_ChIP-Seq_HGPS_Human0.99459190
117SCL_19346495_ChIP-Seq_HPC-7_Human0.98545529
118NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.97772008
119SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97659021
120IRF8_21731497_ChIP-ChIP_J774_Mouse0.97487729
121SMAD4_21741376_ChIP-Seq_EPCs_Human0.97440764
122CDX2_22108803_ChIP-Seq_LS180_Human0.97061826
123CRX_20693478_ChIP-Seq_RETINA_Mouse0.96923401
124ARNT_22903824_ChIP-Seq_MCF-7_Human0.96672566
125TP53_22573176_ChIP-Seq_HFKS_Human0.96169596
126AHR_22903824_ChIP-Seq_MCF-7_Human0.95922273
127OCT4_21477851_ChIP-Seq_ESCs_Mouse0.95710346
128NANOG_19829295_ChIP-Seq_ESCs_Human0.95389366
129SOX2_19829295_ChIP-Seq_ESCs_Human0.95389366
130ELF1_17652178_ChIP-ChIP_JURKAT_Human0.94614919
131FOXP3_21729870_ChIP-Seq_TREG_Human0.94075793
132MYB_26560356_Chip-Seq_TH2_Human0.92980259
133DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.92125720
134* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.92015971
135TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89839584
136NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.89741106
137SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.88651313
138EST1_17652178_ChIP-ChIP_JURKAT_Human0.88525578
139SOX2_18555785_ChIP-Seq_MESCs_Mouse0.87093895
140KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.86792880
141TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.86139180
142POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.86083925
143EZH2_27294783_Chip-Seq_NPCs_Mouse0.85820088
144POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.84639319
145TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84639319
146TFEB_21752829_ChIP-Seq_HELA_Human0.82849705
147* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82057270
148MYC_19079543_ChIP-ChIP_MESCs_Mouse0.81970305
149CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81725867
150IGF1R_20145208_ChIP-Seq_DFB_Human0.81708619
151NANOG_18555785_Chip-Seq_ESCs_Mouse0.80923231
152CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.79867772
153VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.79587191
154E2F1_18555785_Chip-Seq_ESCs_Mouse0.79296911
155MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.78410097
156GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77894314
157SPI1_23547873_ChIP-Seq_NB4_Human0.77146153
158FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77081474
159MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.76578702
160SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.75128824
161SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.74225978
162RUNX_20019798_ChIP-Seq_JUKART_Human0.73420316
163IRF1_19129219_ChIP-ChIP_H3396_Human0.72489596
164DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.72262501
165IRF8_22096565_ChIP-ChIP_GC-B_Human0.71762330
166ZFP57_27257070_Chip-Seq_ESCs_Mouse0.71558008
167EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.71548291

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.94973530
2MP0003195_calcinosis3.66752936
3MP0010094_abnormal_chromosome_stability3.47613030
4MP0008058_abnormal_DNA_repair3.27878054
5MP0008057_abnormal_DNA_replication3.23017898
6MP0003787_abnormal_imprinting3.16211358
7MP0003111_abnormal_nucleus_morphology3.10197060
8MP0003693_abnormal_embryo_hatching2.88695180
9MP0003077_abnormal_cell_cycle2.79414730
10MP0003646_muscle_fatigue2.78199370
11MP0008007_abnormal_cellular_replicative2.78183161
12MP0008877_abnormal_DNA_methylation2.55372732
13MP0003121_genomic_imprinting2.53798103
14MP0002396_abnormal_hematopoietic_system2.51816240
15MP0005075_abnormal_melanosome_morpholog2.47412468
16MP0005645_abnormal_hypothalamus_physiol2.06326799
17MP0010307_abnormal_tumor_latency2.03785473
18MP0003890_abnormal_embryonic-extraembry1.95267484
19MP0004808_abnormal_hematopoietic_stem1.94908941
20MP0006292_abnormal_olfactory_placode1.94439553
21MP0005551_abnormal_eye_electrophysiolog1.91406222
22MP0005253_abnormal_eye_physiology1.89674506
23MP0004957_abnormal_blastocyst_morpholog1.87713847
24MP0006072_abnormal_retinal_apoptosis1.81313394
25MP0002876_abnormal_thyroid_physiology1.77998903
26MP0004043_abnormal_pH_regulation1.76739403
27MP0005646_abnormal_pituitary_gland1.75158701
28MP0003172_abnormal_lysosome_physiology1.71316964
29MP0001986_abnormal_taste_sensitivity1.69584342
30MP0003786_premature_aging1.56385144
31MP0000350_abnormal_cell_proliferation1.55933897
32MP0000566_synostosis1.50543946
33MP0003011_delayed_dark_adaptation1.46324615
34MP0002132_abnormal_respiratory_system1.45167685
35MP0002638_abnormal_pupillary_reflex1.43496068
36MP0003937_abnormal_limbs/digits/tail_de1.43072832
37MP0003763_abnormal_thymus_physiology1.41244276
38MP0000015_abnormal_ear_pigmentation1.41104821
39MP0005076_abnormal_cell_differentiation1.37244131
40MP0002163_abnormal_gland_morphology1.30972360
41MP0001968_abnormal_touch/_nociception1.30326107
42MP0004885_abnormal_endolymph1.29977076
43MP0005380_embryogenesis_phenotype1.29683790
44MP0001672_abnormal_embryogenesis/_devel1.29683790
45MP0001293_anophthalmia1.29257130
46MP0001486_abnormal_startle_reflex1.29175782
47MP0008995_early_reproductive_senescence1.28740174
48MP0010352_gastrointestinal_tract_polyps1.27934911
49MP0001984_abnormal_olfaction1.27254356
50MP0009745_abnormal_behavioral_response1.27149872
51MP0009697_abnormal_copulation1.25453471
52MP0003123_paternal_imprinting1.24264279
53MP0002751_abnormal_autonomic_nervous1.23967180
54MP0000685_abnormal_immune_system1.22385053
55MP0008872_abnormal_physiological_respon1.21135736
56MP0003943_abnormal_hepatobiliary_system1.19164318
57MP0004270_analgesia1.18965910
58MP0003880_abnormal_central_pattern1.17943438
59MP0002084_abnormal_developmental_patter1.17034293
60MP0001835_abnormal_antigen_presentation1.16649553
61MP0003252_abnormal_bile_duct1.16505698
62MP0002102_abnormal_ear_morphology1.15301905
63MP0004197_abnormal_fetal_growth/weight/1.14416262
64MP0000631_abnormal_neuroendocrine_gland1.14177556
65MP0002210_abnormal_sex_determination1.12499275
66MP0010329_abnormal_lipoprotein_level1.12288736
67MP0000778_abnormal_nervous_system1.11998016
68MP0003984_embryonic_growth_retardation1.11882470
69MP0000703_abnormal_thymus_morphology1.11577182
70MP0005174_abnormal_tail_pigmentation1.10294420
71MP0002088_abnormal_embryonic_growth/wei1.09950287
72MP0002160_abnormal_reproductive_system1.08647774
73MP0002272_abnormal_nervous_system1.08642408
74MP0008932_abnormal_embryonic_tissue1.08199317
75MP0001730_embryonic_growth_arrest1.07971420
76MP0002085_abnormal_embryonic_tissue1.07923914
77MP0003122_maternal_imprinting1.06544827
78MP0003938_abnormal_ear_development1.06544428
79MP0004924_abnormal_behavior1.06415194
80MP0005386_behavior/neurological_phenoty1.06415194
81MP0002557_abnormal_social/conspecific_i1.05435918
82MP0005503_abnormal_tendon_morphology1.05048742
83MP0003385_abnormal_body_wall1.04704593
84MP0002398_abnormal_bone_marrow1.03632157
85MP0001501_abnormal_sleep_pattern1.02856634
86MP0002009_preneoplasia1.02496957
87MP0002938_white_spotting1.02026437
88MP0001119_abnormal_female_reproductive1.01852065
89MP0002909_abnormal_adrenal_gland1.01706710
90MP0000432_abnormal_head_morphology1.01532000
91MP0003935_abnormal_craniofacial_develop1.00440355
92MP0001697_abnormal_embryo_size0.99610059
93MP0001286_abnormal_eye_development0.99037314
94MP0005389_reproductive_system_phenotype0.98929976
95MP0002063_abnormal_learning/memory/cond0.98784170
96MP0002086_abnormal_extraembryonic_tissu0.98757791
97MP0000490_abnormal_crypts_of0.98641211
98MP0009703_decreased_birth_body0.98028068
99MP0002928_abnormal_bile_duct0.96032359
100MP0001188_hyperpigmentation0.95497590
101MP0002735_abnormal_chemical_nociception0.94935471
102MP0009278_abnormal_bone_marrow0.94808667
103MP0009672_abnormal_birth_weight0.94181189
104MP0003755_abnormal_palate_morphology0.92925223
105MP0002064_seizures0.92535398
106MP0000313_abnormal_cell_death0.92080010
107MP0002277_abnormal_respiratory_mucosa0.91158256
108MP0004133_heterotaxia0.90351998
109MP0002092_abnormal_eye_morphology0.90118674
110MP0003698_abnormal_male_reproductive0.88632750
111MP0002177_abnormal_outer_ear0.88404571
112MP0001929_abnormal_gametogenesis0.88227080
113MP0003635_abnormal_synaptic_transmissio0.88163065
114MP0003567_abnormal_fetal_cardiomyocyte0.88029369
115MP0001790_abnormal_immune_system0.87462123
116MP0005387_immune_system_phenotype0.87462123
117MP0006054_spinal_hemorrhage0.87373394
118MP0001545_abnormal_hematopoietic_system0.87030373
119MP0005397_hematopoietic_system_phenotyp0.87030373
120MP0005220_abnormal_exocrine_pancreas0.86298812
121MP0001502_abnormal_circadian_rhythm0.86262480
122MP0009046_muscle_twitch0.85584070
123MP0002095_abnormal_skin_pigmentation0.85415875
124MP0005310_abnormal_salivary_gland0.84994295
125MP0001800_abnormal_humoral_immune0.84992208
126MP0002109_abnormal_limb_morphology0.84216314
127MP0001324_abnormal_eye_pigmentation0.82867099
128MP0005379_endocrine/exocrine_gland_phen0.82498145
129MP0000383_abnormal_hair_follicle0.82347186
130MP0001485_abnormal_pinna_reflex0.82012621
131MP0000428_abnormal_craniofacial_morphol0.81831229
132MP0003724_increased_susceptibility_to0.81342500
133MP0002019_abnormal_tumor_incidence0.81100461
134MP0004742_abnormal_vestibular_system0.81025282
135MP0001919_abnormal_reproductive_system0.80576056
136MP0003045_fibrosis0.80546897
137MP0002080_prenatal_lethality0.80541521
138MP0003866_abnormal_defecation0.80101647
139MP0003183_abnormal_peptide_metabolism0.80043475
140MP0000371_diluted_coat_color0.79996843
141MP0002723_abnormal_immune_serum0.79927340
142MP0002229_neurodegeneration0.79798386
143MP0001145_abnormal_male_reproductive0.79473643
144MP0005367_renal/urinary_system_phenotyp0.79082066
145MP0000516_abnormal_urinary_system0.79082066
146MP0010030_abnormal_orbit_morphology0.78923395
147MP0002116_abnormal_craniofacial_bone0.78789806
148MP0004142_abnormal_muscle_tone0.78606079
149MP0005671_abnormal_response_to0.78231712
150MP0000427_abnormal_hair_cycle0.77974282
151MP0000653_abnormal_sex_gland0.77728928
152MP0001346_abnormal_lacrimal_gland0.76194061
153MP0002420_abnormal_adaptive_immunity0.76131636
154MP0008775_abnormal_heart_ventricle0.76121548
155MP0003941_abnormal_skin_development0.75724808
156MP0002572_abnormal_emotion/affect_behav0.75654746
157MP0002168_other_aberrant_phenotype0.74948369
158MP0002693_abnormal_pancreas_physiology0.74615222
159MP0002166_altered_tumor_susceptibility0.74561813
160MP0002697_abnormal_eye_size0.74365447
161MP0000689_abnormal_spleen_morphology0.74281830
162MP0004147_increased_porphyrin_level0.74227205
163MP0002067_abnormal_sensory_capabilities0.74102075
164MP0002233_abnormal_nose_morphology0.73282764
165MP0009333_abnormal_splenocyte_physiolog0.72413787
166MP0003115_abnormal_respiratory_system0.72205423
167MP0005391_vision/eye_phenotype0.72152789
168MP0003690_abnormal_glial_cell0.71944715
169MP0001819_abnormal_immune_cell0.71790195
170MP0000716_abnormal_immune_system0.71673075
171MP0002722_abnormal_immune_system0.71460955
172MP0002452_abnormal_antigen_presenting0.70468997
173MP0002736_abnormal_nociception_after0.70264614
174MP0005167_abnormal_blood-brain_barrier0.69836419
175MP0002837_dystrophic_cardiac_calcinosis0.68088286

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.27164702
2Chromsome breakage (HP:0040012)4.16293160
3Pancreatic cysts (HP:0001737)3.90193666
4Abnormality of the fingertips (HP:0001211)3.86840553
5Pancreatic fibrosis (HP:0100732)3.86172588
6Volvulus (HP:0002580)3.52892373
7True hermaphroditism (HP:0010459)3.49646055
8Abnormality of midbrain morphology (HP:0002418)3.40594764
9Molar tooth sign on MRI (HP:0002419)3.40594764
10Abnormality of the renal cortex (HP:0011035)3.21905823
11Bile duct proliferation (HP:0001408)3.10502214
12Abnormal biliary tract physiology (HP:0012439)3.10502214
13Ectopic kidney (HP:0000086)3.04970216
14Hyperventilation (HP:0002883)2.87006140
15Cystic liver disease (HP:0006706)2.86550669
16Birth length less than 3rd percentile (HP:0003561)2.77804674
17Absent speech (HP:0001344)2.76982215
18Syringomyelia (HP:0003396)2.76528696
19Spinal cord lesions (HP:0100561)2.76528696
20Abnormality of chromosome stability (HP:0003220)2.76210753
21Tubulointerstitial nephritis (HP:0001970)2.76011958
22Congenital stationary night blindness (HP:0007642)2.72913210
23Albinism (HP:0001022)2.64508411
24Absent frontal sinuses (HP:0002688)2.62527559
25Acute myeloid leukemia (HP:0004808)2.62137796
26Abnormal drinking behavior (HP:0030082)2.60799491
27Polydipsia (HP:0001959)2.60799491
28Aplasia/Hypoplasia of the uvula (HP:0010293)2.60453205
29Lip pit (HP:0100267)2.55502374
30Abolished electroretinogram (ERG) (HP:0000550)2.52242869
31Meckel diverticulum (HP:0002245)2.50449406
32Gaze-evoked nystagmus (HP:0000640)2.44532834
33Abnormality of the preputium (HP:0100587)2.43691004
34Prostate neoplasm (HP:0100787)2.43402248
35Broad alveolar ridges (HP:0000187)2.40716584
36Abnormality of the ileum (HP:0001549)2.38593632
37Severe combined immunodeficiency (HP:0004430)2.35685448
38Medulloblastoma (HP:0002885)2.35621033
39Genetic anticipation (HP:0003743)2.35511802
40Renal cortical cysts (HP:0000803)2.32469472
41Long eyelashes (HP:0000527)2.30688110
42Panhypogammaglobulinemia (HP:0003139)2.29730286
43Papillary thyroid carcinoma (HP:0002895)2.26368923
44Abnormal delayed hypersensitivity skin test (HP:0002963)2.25958117
45Stomach cancer (HP:0012126)2.24345449
46Myelodysplasia (HP:0002863)2.24275726
47Hematochezia (HP:0002573)2.23601606
48Abnormality of DNA repair (HP:0003254)2.22547212
49Tubulointerstitial abnormality (HP:0001969)2.21980177
50Intestinal atresia (HP:0011100)2.21336551
51Deep philtrum (HP:0002002)2.20014865
52Medial flaring of the eyebrow (HP:0010747)2.19935529
53Patellar aplasia (HP:0006443)2.18873022
54Abnormality of the carotid arteries (HP:0005344)2.17163821
55Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.16936970
56Short 4th metacarpal (HP:0010044)2.16936970
57Type II lissencephaly (HP:0007260)2.15669631
58Congenital hepatic fibrosis (HP:0002612)2.15000220
59Clubbing of toes (HP:0100760)2.11454235
60Alveolar cell carcinoma (HP:0006519)2.10879348
61Neoplasm of the tracheobronchial system (HP:0100552)2.10273015
62Urethral obstruction (HP:0000796)2.10167203
63Hemiparesis (HP:0001269)2.10142669
64Acute lymphatic leukemia (HP:0006721)2.09744521
65Nephroblastoma (Wilms tumor) (HP:0002667)2.09597128
66Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.07717539
67Postaxial foot polydactyly (HP:0001830)2.05514948
68Shawl scrotum (HP:0000049)2.05440580
69Embryonal renal neoplasm (HP:0011794)2.04607530
70Hypothermia (HP:0002045)2.03036864
71Abnormality of the intervertebral disk (HP:0005108)2.02529833
72Amyotrophic lateral sclerosis (HP:0007354)2.01522880
73Broad-based gait (HP:0002136)2.01468124
74Focal seizures (HP:0007359)2.01182983
75Abnormality of the labia minora (HP:0012880)2.01173856
76Febrile seizures (HP:0002373)2.00915660
77Aplasia/Hypoplasia of the patella (HP:0006498)2.00299499
78Abnormality of eosinophils (HP:0001879)1.99740064
79Anal stenosis (HP:0002025)1.99329907
80Pachygyria (HP:0001302)1.98189393
81Vitreoretinal degeneration (HP:0000655)1.97697778
82Severe visual impairment (HP:0001141)1.97082494
83Widely spaced teeth (HP:0000687)1.95740089
84Aqueductal stenosis (HP:0002410)1.95438149
85Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.95188872
86Attenuation of retinal blood vessels (HP:0007843)1.95122376
87Duodenal stenosis (HP:0100867)1.94946871
88Small intestinal stenosis (HP:0012848)1.94946871
89Progressive inability to walk (HP:0002505)1.94635529
90Fair hair (HP:0002286)1.92450198
91Aplasia/Hypoplasia of the tongue (HP:0010295)1.92417356
92Postaxial hand polydactyly (HP:0001162)1.92090672
93Neoplasm of the oral cavity (HP:0100649)1.91218427
94Hemiplegia (HP:0002301)1.89887700
95Abnormal rod and cone electroretinograms (HP:0008323)1.89187853
96Colon cancer (HP:0003003)1.89102495
97Prominent nose (HP:0000448)1.87850508
98Recurrent bronchitis (HP:0002837)1.87067813
99Tubular atrophy (HP:0000092)1.86834596
100Long clavicles (HP:0000890)1.85778515
101Aplasia/Hypoplasia of the tibia (HP:0005772)1.85460782
102Tented upper lip vermilion (HP:0010804)1.84751618
103Increased nuchal translucency (HP:0010880)1.83894384
104Impulsivity (HP:0100710)1.83402774
105Sloping forehead (HP:0000340)1.83383562
106Polyuria (HP:0000103)1.83082097
107Progressive cerebellar ataxia (HP:0002073)1.81438504
108Narrow forehead (HP:0000341)1.80406151
109Agammaglobulinemia (HP:0004432)1.80333134
110Absent/shortened dynein arms (HP:0200106)1.79851937
111Dynein arm defect of respiratory motile cilia (HP:0012255)1.79851937
112Abnormality of the incisor (HP:0000676)1.79127337
113Pendular nystagmus (HP:0012043)1.78161705
114Adactyly (HP:0009776)1.76955161
115Keratoconus (HP:0000563)1.75528117
116Increased corneal curvature (HP:0100692)1.75528117
117Glioma (HP:0009733)1.75131600
118Gonadotropin excess (HP:0000837)1.74091779
119Excessive salivation (HP:0003781)1.73521758
120Tachypnea (HP:0002789)1.72844765
121Drooling (HP:0002307)1.72474990
122Tubulointerstitial fibrosis (HP:0005576)1.71567491
123Truncal obesity (HP:0001956)1.71310856
124Stomatitis (HP:0010280)1.70837089
125Abnormality of B cell number (HP:0010975)1.70592757
126Chronic mucocutaneous candidiasis (HP:0002728)1.70374942
127Recurrent cutaneous fungal infections (HP:0011370)1.70374942
128Optic neuritis (HP:0100653)1.69583599
129Retrobulbar optic neuritis (HP:0100654)1.69583599
130Hamartoma of the eye (HP:0010568)1.69037720
131Cupped ear (HP:0000378)1.68820639
132Abnormality of the renal collecting system (HP:0004742)1.68580652
133Duplicated collecting system (HP:0000081)1.68458627
134Abnormality of the columella (HP:0009929)1.67623337
135Trigonocephaly (HP:0000243)1.67222105
136Broad palm (HP:0001169)1.66681030
137Abnormality of vitamin B metabolism (HP:0004340)1.66615771
138Neoplasm of the lung (HP:0100526)1.66306115
139Abnormality of the nasal septum (HP:0000419)1.64087102
140Lissencephaly (HP:0001339)1.63263336
141Abnormality of the frontal sinuses (HP:0002687)1.62812262
1423-Methylglutaconic aciduria (HP:0003535)1.61886333
143Bone marrow hypocellularity (HP:0005528)1.61401484
144Small epiphyses (HP:0010585)1.60960314
145Anencephaly (HP:0002323)1.60804692
146Hypoplasia of the maxilla (HP:0000327)1.60314901
147Entropion (HP:0000621)1.60038555
148Hypoplastic ischia (HP:0003175)1.59947489
149Ependymoma (HP:0002888)1.59541265
150Sparse lateral eyebrow (HP:0005338)1.59401770
151Thyroiditis (HP:0100646)1.59367033
152Occipital encephalocele (HP:0002085)1.59144847
153Genital tract atresia (HP:0001827)1.58735574
154Limited elbow extension (HP:0001377)1.58022421
155Abnormality of incisor morphology (HP:0011063)1.57149121
156Ketoacidosis (HP:0001993)1.57108535
157Protruding tongue (HP:0010808)1.57074691
158Short thumb (HP:0009778)1.57014203
159Narrow palate (HP:0000189)1.56016100
160Midline defect of the nose (HP:0004122)1.54833285
161Abnormality of the duodenum (HP:0002246)1.54780944
162Optic nerve coloboma (HP:0000588)1.53074183
163Gastrointestinal carcinoma (HP:0002672)1.51867187
164Malignant gastrointestinal tract tumors (HP:0006749)1.51867187
165Flat capital femoral epiphysis (HP:0003370)1.51771058
166Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.51668487
167Chronic hepatic failure (HP:0100626)1.50500994
168Abnormality of the astrocytes (HP:0100707)1.50149663
169Astrocytoma (HP:0009592)1.50149663
170Hypoplastic iliac wings (HP:0002866)1.48931134
171Amaurosis fugax (HP:0100576)1.48734733
172Microtia (HP:0008551)1.48727736
173Abnormal hair whorl (HP:0010721)1.48689627
174Rhabdomyosarcoma (HP:0002859)1.48563991
175Supernumerary ribs (HP:0005815)1.47724504
176Short middle phalanx of the 5th finger (HP:0004220)1.47166257
177Hypoplastic labia majora (HP:0000059)1.46735642
178Convex nasal ridge (HP:0000444)1.45712709
179Increased number of teeth (HP:0011069)1.45376750
180Nephronophthisis (HP:0000090)1.45225376
181Heterotopia (HP:0002282)1.44936386
182Abnormality of the renal medulla (HP:0100957)1.44266539
183Facial hemangioma (HP:0000329)1.43993933
184Short middle phalanx of finger (HP:0005819)1.42589581
185Capillary hemangiomas (HP:0005306)1.42428574
186Cafe-au-lait spot (HP:0000957)1.41483145
187Supernumerary bones of the axial skeleton (HP:0009144)1.41436756
188Abnormality of the metopic suture (HP:0005556)1.41178870
189Abnormality of the prostate (HP:0008775)1.40166609

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRD44.04177527
2CDK123.38310589
3CDC73.35805065
4LATS12.99470925
5SRPK12.98112261
6MKNK22.90148244
7MKNK12.56278370
8EPHA32.50616770
9FGFR22.47543140
10NEK22.12702691
11MARK12.08128483
12ACVR1B2.04474139
13ZAK2.04360483
14STK32.00932573
15MAP4K22.00195866
16MAP3K41.99206739
17STK38L1.96234483
18NTRK31.88763825
19STK391.86186858
20ERBB31.82495567
21BMPR1B1.77692167
22OXSR11.77180378
23GRK11.76060668
24ATR1.74825170
25TGFBR11.70329904
26CDC42BPA1.69442881
27TNK21.68371351
28PINK11.66039311
29PLK41.64268269
30ADRBK21.63151550
31NTRK21.58140290
32AKT31.57498814
33TXK1.57448420
34CDK91.51875404
35MAP3K141.48536148
36CHEK21.48359574
37JAK31.40927475
38TTK1.38577159
39PLK31.37651623
40NUAK11.37068719
41SGK21.34257804
42CDK81.32696192
43CCNB11.32573608
44CHUK1.32049344
45WNK41.31652334
46YES11.30334311
47CAMK1D1.29152995
48ATM1.27776752
49SIK31.27654246
50PAK31.27537814
51PLK11.26694906
52CHEK11.20924710
53CDK71.19241332
54TNIK1.17636250
55STK41.16698467
56DYRK31.14296936
57PASK1.12718442
58TEC1.12441114
59AURKB1.10398345
60FRK1.08604673
61FES1.08182438
62RPS6KA41.05194547
63BCR1.04862571
64MELK1.04289324
65TIE11.04023578
66MAP3K71.02818795
67SGK31.00814583
68CAMKK21.00035108
69INSRR0.98959259
70MST40.97127021
71SIK20.95581992
72EIF2AK20.94748362
73CDK30.94334288
74IRAK40.90552882
75TSSK60.90533670
76PLK20.89609302
77CAMK1G0.89132006
78PIM10.89024867
79CDK40.86785490
80EIF2AK30.85280094
81FER0.85111775
82WNK30.84840485
83SYK0.83898764
84CDK20.80302575
85VRK10.79681737
86FGFR30.77822046
87MAP2K70.77419694
88MAPKAPK30.74887169
89STK110.74830485
90CDK60.73887991
91* CDK10.73034739
92LYN0.70897236
93NLK0.70182695
94STK100.70025505
95FGFR40.69742879
96EPHA40.69148802
97PTK2B0.68514140
98MAPK130.68257085
99PRKCE0.67625488
100BLK0.67617071
101ITK0.67308833
102PRKCQ0.67038915
103LCK0.66328642
104NEK60.66183750
105BMPR20.65962861
106ERBB20.65264397
107CLK10.63725576
108TRPM70.60785306
109WEE10.60265907
110BRSK20.59874192
111PIK3CA0.59548051
112DYRK1A0.59356513
113MAPK140.59084460
114PRKCZ0.58744669
115BUB10.58743920
116SGK4940.57077022
117SGK2230.57077022
118MTOR0.57010382
119TAOK30.56922140
120MAPK110.56694239
121TYRO30.56386815
122MAP4K10.56138605
123DYRK20.55800230
124PRKAA10.55341741
125ZAP700.53863545
126LATS20.53661741
127BTK0.52466133
128CSNK1G20.52353652
129ABL10.51312683
130NEK90.50611195
131PDGFRB0.50336734
132RPS6KB10.50300147
133HCK0.46674372
134IGF1R0.46198281
135AKT10.45771318
136CASK0.45379485
137PRKAA20.45239721
138PRKDC0.44647849
139MAP3K130.43812080
140PRKD10.43142351
141GSK3B0.42956673
142CSNK1G10.42519408
143DAPK20.42089213
144MAP2K60.42072770
145IKBKB0.41913399
146STK240.41438211
147IRAK10.40699036
148TYK20.40507627
149IKBKE0.40346419
150MARK30.40315453
151MAPK150.40257774
152CSNK1D0.39682238
153MAPK80.39044393
154CSF1R0.38852361
155JAK10.38078186
156KIT0.37826616
157HIPK20.37783121
158FLT30.37642734
159* MAPK100.37363214
160MAPK10.37322538
161RPS6KB20.37311863
162FGR0.36347501
163SGK10.35939874
164TAF10.35894174
165CSK0.35810448

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.71434073
2Fanconi anemia pathway_Homo sapiens_hsa034602.69042282
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.42994717
4Cell cycle_Homo sapiens_hsa041102.36665483
5Mismatch repair_Homo sapiens_hsa034302.34782993
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.31228968
7Linoleic acid metabolism_Homo sapiens_hsa005912.20200587
8Basal transcription factors_Homo sapiens_hsa030222.18965917
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.17849296
10Spliceosome_Homo sapiens_hsa030402.17316314
11Homologous recombination_Homo sapiens_hsa034402.16126882
12Base excision repair_Homo sapiens_hsa034102.15090888
13Non-homologous end-joining_Homo sapiens_hsa034502.13502827
14ABC transporters_Homo sapiens_hsa020102.12021500
15RNA transport_Homo sapiens_hsa030131.97597799
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.97143722
17DNA replication_Homo sapiens_hsa030301.96800464
18Type I diabetes mellitus_Homo sapiens_hsa049401.94508550
19mRNA surveillance pathway_Homo sapiens_hsa030151.87246817
20Butanoate metabolism_Homo sapiens_hsa006501.86208351
21Ether lipid metabolism_Homo sapiens_hsa005651.85859040
22RNA degradation_Homo sapiens_hsa030181.79708109
23Regulation of autophagy_Homo sapiens_hsa041401.72614272
24Dorso-ventral axis formation_Homo sapiens_hsa043201.60328046
25Nucleotide excision repair_Homo sapiens_hsa034201.59187656
26Herpes simplex infection_Homo sapiens_hsa051681.53470854
27Selenocompound metabolism_Homo sapiens_hsa004501.53382543
28Transcriptional misregulation in cancer_Homo sapiens_hsa052021.52310927
29p53 signaling pathway_Homo sapiens_hsa041151.49140393
30One carbon pool by folate_Homo sapiens_hsa006701.48455907
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.47966504
32Phototransduction_Homo sapiens_hsa047441.47268296
33MicroRNAs in cancer_Homo sapiens_hsa052061.41792655
34NF-kappa B signaling pathway_Homo sapiens_hsa040641.40088617
35Primary immunodeficiency_Homo sapiens_hsa053401.35740084
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.35614141
37Lysine degradation_Homo sapiens_hsa003101.30219738
38RNA polymerase_Homo sapiens_hsa030201.30196709
39Asthma_Homo sapiens_hsa053101.28246583
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.25627395
41Measles_Homo sapiens_hsa051621.25197419
42Insulin secretion_Homo sapiens_hsa049111.25125251
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20725917
44Staphylococcus aureus infection_Homo sapiens_hsa051501.19132222
45Small cell lung cancer_Homo sapiens_hsa052221.16422188
46Viral carcinogenesis_Homo sapiens_hsa052031.14130351
47HTLV-I infection_Homo sapiens_hsa051661.10224424
48Hepatitis B_Homo sapiens_hsa051611.10089228
49Epstein-Barr virus infection_Homo sapiens_hsa051691.09494034
50Chronic myeloid leukemia_Homo sapiens_hsa052201.08476806
51Renin secretion_Homo sapiens_hsa049241.08232492
52Prostate cancer_Homo sapiens_hsa052151.06568848
53Nicotine addiction_Homo sapiens_hsa050331.06493557
54Systemic lupus erythematosus_Homo sapiens_hsa053221.06458308
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.05477645
56Colorectal cancer_Homo sapiens_hsa052101.05213765
57Intestinal immune network for IgA production_Homo sapiens_hsa046721.04633415
58Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04379896
59Notch signaling pathway_Homo sapiens_hsa043301.03878395
60Olfactory transduction_Homo sapiens_hsa047401.03014882
61Glutamatergic synapse_Homo sapiens_hsa047241.02414619
62Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99751437
63Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.99596999
64Antigen processing and presentation_Homo sapiens_hsa046120.99130956
65Influenza A_Homo sapiens_hsa051640.98942990
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.98777143
67Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.97327664
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97313805
69Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.97113806
70Jak-STAT signaling pathway_Homo sapiens_hsa046300.97011949
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.96089359
72Propanoate metabolism_Homo sapiens_hsa006400.94873134
73Adherens junction_Homo sapiens_hsa045200.94255540
74T cell receptor signaling pathway_Homo sapiens_hsa046600.93749735
75NOD-like receptor signaling pathway_Homo sapiens_hsa046210.93533554
76Pancreatic cancer_Homo sapiens_hsa052120.92562110
77Hematopoietic cell lineage_Homo sapiens_hsa046400.91390751
78Glycerolipid metabolism_Homo sapiens_hsa005610.91151282
79Taste transduction_Homo sapiens_hsa047420.90902731
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.90255156
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.87932773
82Ovarian steroidogenesis_Homo sapiens_hsa049130.87268040
83Cyanoamino acid metabolism_Homo sapiens_hsa004600.86092337
84FoxO signaling pathway_Homo sapiens_hsa040680.85401151
85Nitrogen metabolism_Homo sapiens_hsa009100.84902562
86Thyroid hormone synthesis_Homo sapiens_hsa049180.84665647
87Inositol phosphate metabolism_Homo sapiens_hsa005620.84513821
88Arachidonic acid metabolism_Homo sapiens_hsa005900.83894964
89TGF-beta signaling pathway_Homo sapiens_hsa043500.83766922
90RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.83371109
91Circadian entrainment_Homo sapiens_hsa047130.82315557
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.81882325
93Retinol metabolism_Homo sapiens_hsa008300.81590931
94Tryptophan metabolism_Homo sapiens_hsa003800.81319993
95Amphetamine addiction_Homo sapiens_hsa050310.81139889
96Pyrimidine metabolism_Homo sapiens_hsa002400.80695517
97Basal cell carcinoma_Homo sapiens_hsa052170.80081065
98Histidine metabolism_Homo sapiens_hsa003400.79574755
99Viral myocarditis_Homo sapiens_hsa054160.79164127
100Wnt signaling pathway_Homo sapiens_hsa043100.78691683
101Caffeine metabolism_Homo sapiens_hsa002320.78108051
102Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.77731083
103Endometrial cancer_Homo sapiens_hsa052130.75270921
104Long-term depression_Homo sapiens_hsa047300.74851165
105Salivary secretion_Homo sapiens_hsa049700.74787492
106Apoptosis_Homo sapiens_hsa042100.74601586
107B cell receptor signaling pathway_Homo sapiens_hsa046620.74431714
108Morphine addiction_Homo sapiens_hsa050320.73805081
109Pathways in cancer_Homo sapiens_hsa052000.73011301
110Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.72731104
111Fatty acid degradation_Homo sapiens_hsa000710.72646532
112Acute myeloid leukemia_Homo sapiens_hsa052210.70732489
113Peroxisome_Homo sapiens_hsa041460.70506716
114TNF signaling pathway_Homo sapiens_hsa046680.70264157
115Hippo signaling pathway_Homo sapiens_hsa043900.69041135
116Non-small cell lung cancer_Homo sapiens_hsa052230.68817348
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.68272050
118Allograft rejection_Homo sapiens_hsa053300.67274010
119Oocyte meiosis_Homo sapiens_hsa041140.66962460
120Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.66591598
121Dopaminergic synapse_Homo sapiens_hsa047280.66335898
122Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66152806
123Prolactin signaling pathway_Homo sapiens_hsa049170.65747746
124Osteoclast differentiation_Homo sapiens_hsa043800.65635675
125cAMP signaling pathway_Homo sapiens_hsa040240.65068876
126Purine metabolism_Homo sapiens_hsa002300.64789442
127Toxoplasmosis_Homo sapiens_hsa051450.64374842
128Circadian rhythm_Homo sapiens_hsa047100.63394268
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.62818489
130Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62537898
131Axon guidance_Homo sapiens_hsa043600.61867838
132Toll-like receptor signaling pathway_Homo sapiens_hsa046200.61455997
133Alcoholism_Homo sapiens_hsa050340.61352759
134Fatty acid metabolism_Homo sapiens_hsa012120.59167771
135Melanoma_Homo sapiens_hsa052180.58872656
136Thyroid cancer_Homo sapiens_hsa052160.57829216
137Vascular smooth muscle contraction_Homo sapiens_hsa042700.57752162
138Complement and coagulation cascades_Homo sapiens_hsa046100.57303621
139Chemical carcinogenesis_Homo sapiens_hsa052040.56693552
140Cocaine addiction_Homo sapiens_hsa050300.56476650
141Insulin resistance_Homo sapiens_hsa049310.56436594
142Hedgehog signaling pathway_Homo sapiens_hsa043400.56303053
143Legionellosis_Homo sapiens_hsa051340.55624755
144Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.55415702
145mTOR signaling pathway_Homo sapiens_hsa041500.55250714
146Graft-versus-host disease_Homo sapiens_hsa053320.54752145
147Autoimmune thyroid disease_Homo sapiens_hsa053200.54639210
148Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53126235
149Aldosterone synthesis and secretion_Homo sapiens_hsa049250.52687682
150Fat digestion and absorption_Homo sapiens_hsa049750.52372048
151Chemokine signaling pathway_Homo sapiens_hsa040620.52252360
152Choline metabolism in cancer_Homo sapiens_hsa052310.51867762
153GABAergic synapse_Homo sapiens_hsa047270.51551109
154Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.50173352
155Serotonergic synapse_Homo sapiens_hsa047260.49414015
156PI3K-Akt signaling pathway_Homo sapiens_hsa041510.49052775
157Proteoglycans in cancer_Homo sapiens_hsa052050.48918832
158beta-Alanine metabolism_Homo sapiens_hsa004100.48377870
159Leishmaniasis_Homo sapiens_hsa051400.48371672
160Leukocyte transendothelial migration_Homo sapiens_hsa046700.47346227
161ErbB signaling pathway_Homo sapiens_hsa040120.45772459
162AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.45112833
163MAPK signaling pathway_Homo sapiens_hsa040100.44433380
164Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.43923710
165Hepatitis C_Homo sapiens_hsa051600.43246612
166Neurotrophin signaling pathway_Homo sapiens_hsa047220.41401402
167Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41391629
168Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40368977
169Phosphatidylinositol signaling system_Homo sapiens_hsa040700.39349967
170Focal adhesion_Homo sapiens_hsa045100.38847375
171Type II diabetes mellitus_Homo sapiens_hsa049300.37376503

Most similar genes based on co-expression Upload to Enrichr

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