RBMS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1wound healing, spreading of epidermal cells (GO:0035313)4.10568392
2cell adhesion mediated by integrin (GO:0033627)4.04041985
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.69527605
4cell migration involved in heart development (GO:0060973)3.61392730
5vascular endothelial growth factor signaling pathway (GO:0038084)3.36312752
6detection of molecule of bacterial origin (GO:0032490)3.29946316
7endodermal cell differentiation (GO:0035987)3.23555949
8cellular response to interferon-alpha (GO:0035457)3.23347630
9positive regulation of endothelial cell apoptotic process (GO:2000353)3.21303004
10basement membrane organization (GO:0071711)3.16633382
11wound healing, spreading of cells (GO:0044319)3.10942987
12pathway-restricted SMAD protein phosphorylation (GO:0060389)3.02499674
13neutrophil activation involved in immune response (GO:0002283)3.01493258
14positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.99121228
15negative regulation of interleukin-12 production (GO:0032695)2.98842595
16positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.93471004
17positive regulation by symbiont of host defense response (GO:0052509)2.93352437
18modulation by symbiont of host defense response (GO:0052031)2.93352437
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.93352437
20modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.93352437
21positive regulation by organism of defense response of other organism involved in symbiotic interact2.93352437
22modulation by symbiont of host immune response (GO:0052553)2.93352437
23negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.92605979
24negative regulation of cell killing (GO:0031342)2.92605979
25apoptotic cell clearance (GO:0043277)2.91459437
26chondrocyte proliferation (GO:0035988)2.88330200
27protein heterotrimerization (GO:0070208)2.87920611
28substrate-dependent cell migration (GO:0006929)2.87046521
29retina vasculature morphogenesis in camera-type eye (GO:0061299)2.82603822
30axon extension involved in axon guidance (GO:0048846)2.81175810
31neuron projection extension involved in neuron projection guidance (GO:1902284)2.81175810
32regulation of mononuclear cell migration (GO:0071675)2.80632859
33hemidesmosome assembly (GO:0031581)2.79450209
34positive regulation of tolerance induction (GO:0002645)2.79168126
35skin morphogenesis (GO:0043589)2.78791204
36glomerular visceral epithelial cell development (GO:0072015)2.78602604
37positive regulation of gamma-delta T cell activation (GO:0046645)2.75487565
38pinocytosis (GO:0006907)2.73555881
39collagen fibril organization (GO:0030199)2.72430022
40response to laminar fluid shear stress (GO:0034616)2.69494428
41positive regulation of interferon-alpha production (GO:0032727)2.68613010
42hypotonic response (GO:0006971)2.66586100
43embryonic process involved in female pregnancy (GO:0060136)2.63883391
44positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.63872447
45protein localization to endosome (GO:0036010)2.63756842
46low-density lipoprotein particle clearance (GO:0034383)2.62073555
47response to peptidoglycan (GO:0032494)2.59550307
48Arp2/3 complex-mediated actin nucleation (GO:0034314)2.59349289
49plasma membrane repair (GO:0001778)2.59161852
50positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.58052540
51regulation of T cell tolerance induction (GO:0002664)2.56651283
52membrane raft organization (GO:0031579)2.56086955
53mesodermal cell differentiation (GO:0048333)2.56058971
54negative regulation of fatty acid transport (GO:2000192)2.56042681
55regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.55320792
56regulation of interferon-alpha production (GO:0032647)2.53876392
57cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.53831978
58dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.53719475
59regulation of monocyte chemotaxis (GO:0090025)2.53464841
60lymph vessel development (GO:0001945)2.53328363
61regulation of SMAD protein import into nucleus (GO:0060390)2.52366151
62regulation of cholesterol storage (GO:0010885)2.52301488
63sequestering of extracellular ligand from receptor (GO:0035581)2.52051311
64lymphangiogenesis (GO:0001946)2.51021156
65morphogenesis of an endothelium (GO:0003159)2.50444081
66endothelial tube morphogenesis (GO:0061154)2.50444081
67regulation of tolerance induction (GO:0002643)2.49808485
68regulation of B cell receptor signaling pathway (GO:0050855)2.49715893
69positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.48506364
70establishment of endothelial barrier (GO:0061028)2.48048446
71regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.47561135
72hippo signaling (GO:0035329)2.44832094
73detection of external biotic stimulus (GO:0098581)2.44374407
74positive regulation of p38MAPK cascade (GO:1900745)2.43625609
75response to fluid shear stress (GO:0034405)2.43586934
76positive regulation of monocyte chemotaxis (GO:0090026)2.43009843
77positive regulation of epithelial to mesenchymal transition (GO:0010718)2.42785574
78regulation of transforming growth factor beta2 production (GO:0032909)2.42359836
79leukocyte aggregation (GO:0070486)2.42174419
80substrate adhesion-dependent cell spreading (GO:0034446)2.40503600
81mRNA transcription (GO:0009299)2.40395790
82positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.40260940
83regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.39965589
84regulation of dendritic cell antigen processing and presentation (GO:0002604)2.38448690
85response to interferon-alpha (GO:0035455)2.37666760
86endothelial cell morphogenesis (GO:0001886)2.37181858
87natural killer cell mediated cytotoxicity (GO:0042267)2.36711626
88natural killer cell mediated immunity (GO:0002228)2.36711626
89positive regulation of blood vessel endothelial cell migration (GO:0043536)2.36698840
90venous blood vessel morphogenesis (GO:0048845)2.36628695
91macrophage activation involved in immune response (GO:0002281)2.35778278
92pericardium development (GO:0060039)2.35111193
93glomerular epithelial cell development (GO:0072310)2.35088070
94glomerular basement membrane development (GO:0032836)2.34806570
95cell-substrate junction assembly (GO:0007044)2.34476605
96tolerance induction (GO:0002507)2.34150427
97detection of other organism (GO:0098543)2.31785210
98bone trabecula formation (GO:0060346)2.31362130
99response to muramyl dipeptide (GO:0032495)2.30950427
100growth hormone receptor signaling pathway (GO:0060396)2.30915985
101granulocyte activation (GO:0036230)2.30907130
102cell migration involved in sprouting angiogenesis (GO:0002042)2.30551063
103immunoglobulin mediated immune response (GO:0016064)2.29388503
104renal filtration (GO:0097205)2.28839263
105collagen metabolic process (GO:0032963)2.27341947
106barbed-end actin filament capping (GO:0051016)2.26729336
107chondrocyte development (GO:0002063)2.26566671
108production of molecular mediator involved in inflammatory response (GO:0002532)2.25968437
109regulation of integrin-mediated signaling pathway (GO:2001044)2.25470300
110stress fiber assembly (GO:0043149)2.25355110
111platelet-derived growth factor receptor signaling pathway (GO:0048008)2.25128642
112regulation of interferon-beta biosynthetic process (GO:0045357)2.23768255
113detection of biotic stimulus (GO:0009595)2.23671732
114neutrophil activation (GO:0042119)2.23662011
115monocyte chemotaxis (GO:0002548)2.23388289
116blood vessel remodeling (GO:0001974)2.23312827
117fibril organization (GO:0097435)2.23228593
118positive regulation of natural killer cell differentiation (GO:0032825)2.22006184
119positive regulation of chemokine biosynthetic process (GO:0045080)2.21642745
120positive regulation vascular endothelial growth factor production (GO:0010575)2.21249229
121positive regulation of extracellular matrix organization (GO:1903055)2.20844023
122regulation of membrane protein ectodomain proteolysis (GO:0051043)2.19179170
123endothelium development (GO:0003158)2.18972666
124negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.18717462
125vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.18687432
126regulation of integrin activation (GO:0033623)2.18468341
127regulation of macrophage cytokine production (GO:0010935)2.18167004
128positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.16906308
129regulation of T-helper 2 cell differentiation (GO:0045628)2.16825254
130response to interleukin-15 (GO:0070672)2.16642450
131regulation of vitamin D biosynthetic process (GO:0060556)2.16381285
132phagocytosis, engulfment (GO:0006911)2.15874753
133negative regulation of anoikis (GO:2000811)2.15474403
134radial glial cell differentiation (GO:0060019)2.15378840
135collagen catabolic process (GO:0030574)2.15199937
136blood vessel endothelial cell migration (GO:0043534)2.15072436
137patterning of blood vessels (GO:0001569)2.15044956
138regulation of T-helper 1 cell differentiation (GO:0045625)2.14832104
139mRNA transcription from RNA polymerase II promoter (GO:0042789)2.14472108
140negative regulation of cytokine production involved in immune response (GO:0002719)2.14301766
141regulation of tight junction assembly (GO:2000810)2.14000447
142negative regulation of T-helper cell differentiation (GO:0045623)2.13565181
143negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.13565181
144regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.13477468
145positive regulation of SMAD protein import into nucleus (GO:0060391)2.12944025
146regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.12608044
147germ cell migration (GO:0008354)2.11971988
148extracellular matrix disassembly (GO:0022617)2.11558950
149epithelial cell-cell adhesion (GO:0090136)2.11017227
150cellular extravasation (GO:0045123)2.10864122
151lipopolysaccharide-mediated signaling pathway (GO:0031663)2.10301909
152positive regulation of macrophage cytokine production (GO:0060907)2.10294449
153cortical actin cytoskeleton organization (GO:0030866)2.09670322
154positive regulation of receptor recycling (GO:0001921)2.06418728

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.90254641
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.98988500
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.88434835
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.72556612
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.65266909
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.41880505
7RARG_19884340_ChIP-ChIP_MEFs_Mouse3.23783086
8IRF8_22096565_ChIP-ChIP_GC-B_Human3.22587055
9IRF8_21731497_ChIP-ChIP_J774_Mouse3.18820093
10BP1_19119308_ChIP-ChIP_Hs578T_Human3.08978660
11RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.68800909
12CLOCK_20551151_ChIP-Seq_293T_Human2.45503213
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.44497431
14* IRF8_27001747_Chip-Seq_BMDM_Mouse2.39741797
15Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.38370169
16* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.37991017
17NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.37634061
18* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.28555940
19* SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.27276408
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.19400579
21TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.14154129
22STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.12735476
23HIF1A_21447827_ChIP-Seq_MCF-7_Human2.12186081
24SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.08297899
25SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.08297899
26CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.06809454
27RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.02383593
28ELK3_25401928_ChIP-Seq_HUVEC_Human2.01399068
29CJUN_26792858_Chip-Seq_BT549_Human1.87166346
30KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.86500367
31KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.86500367
32KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.86500367
33* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.83412658
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.81846651
35CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.72020999
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.69479204
37GATA2_21666600_ChIP-Seq_HMVEC_Human1.69426937
38BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69425497
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.66788797
40BRD4_25478319_ChIP-Seq_HGPS_Human1.64913181
41KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.64160546
42MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.62981866
43FOXO3_23340844_ChIP-Seq_DLD1_Human1.62784757
44NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.59017958
45STAT6_21828071_ChIP-Seq_BEAS2B_Human1.54901661
46ESR1_21235772_ChIP-Seq_MCF-7_Human1.53153767
47* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.50821525
48SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.47054306
49SALL4_18804426_ChIP-ChIP_XEN_Mouse1.43261198
50IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.41919118
51SOX2_20726797_ChIP-Seq_SW620_Human1.41316412
52MAF_26560356_Chip-Seq_TH1_Human1.40094705
53UBF1/2_26484160_Chip-Seq_HMECs_Human1.39321023
54ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.37936010
55JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.36235127
56TP53_16413492_ChIP-PET_HCT116_Human1.35328592
57NRF2_20460467_ChIP-Seq_MEFs_Mouse1.33841913
58NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.33841913
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.33825605
60STAT4_19710469_ChIP-ChIP_TH1__Mouse1.33248853
61RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32186779
62KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30216661
63NFIB_24661679_ChIP-Seq_LUNG_Mouse1.28910314
64VDR_24763502_ChIP-Seq_THP-1_Human1.28528430
65* VDR_24787735_ChIP-Seq_THP-1_Human1.28407190
66KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.27694952
67RUNX_20019798_ChIP-Seq_JUKART_Human1.26800995
68ATF3_27146783_Chip-Seq_COLON_Human1.25318842
69TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.24749869
70* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.24682367
71ESR2_21235772_ChIP-Seq_MCF-7_Human1.24626466
72MYB_26560356_Chip-Seq_TH2_Human1.23091055
73* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.22613200
74ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21851663
75JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21522919
76P300_27058665_Chip-Seq_ZR-75-30cells_Human1.21035818
77PU_27001747_Chip-Seq_BMDM_Mouse1.20107284
78ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.18797485
79TCF7_22412390_ChIP-Seq_EML_Mouse1.18458170
80VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.17521760
81SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16808771
82P63_26484246_Chip-Seq_KERATINOCYTES_Human1.16301194
83KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.15931276
84CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.15805377
85CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14334569
86KDM2B_26808549_Chip-Seq_DND41_Human1.14319843
87CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.10905852
88TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10896520
89SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10809108
90EP300_21415370_ChIP-Seq_HL-1_Mouse1.10743136
91PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10701419
92FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.10079546
93FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.08906731
94VDR_21846776_ChIP-Seq_THP-1_Human1.07939508
95* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.07891422
96SALL1_21062744_ChIP-ChIP_HESCs_Human1.07438156
97RACK7_27058665_Chip-Seq_MCF-7_Human1.07266579
98TCF4_18268006_ChIP-ChIP_LS174T_Human1.07266507
99* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.06631043
100SPI1_23127762_ChIP-Seq_K562_Human1.05318649
101SPI1_23547873_ChIP-Seq_NB4_Human1.05272722
102SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.04820347
103MYB_26560356_Chip-Seq_TH1_Human1.04817237
104ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.04127833
105AHR_22903824_ChIP-Seq_MCF-7_Human1.03188227
106UTX_26944678_Chip-Seq_JUKART_Human1.02804017
107PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.99429547
108CDX2_20551321_ChIP-Seq_CACO-2_Human0.99090969
109NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.98651943
110PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95880225
111SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.95383863
112* TBX20_22080862_ChIP-Seq_HEART_Mouse0.95142663
113* TBX20_22328084_ChIP-Seq_HEART_Mouse0.95142663
114WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.94606972
115RUNX1_22412390_ChIP-Seq_EML_Mouse0.94172864
116* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93450845
117GATA1_22025678_ChIP-Seq_K562_Human0.92995281
118DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92664555
119THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91884486
120* TP63_23658742_ChIP-Seq_EP156T_Human0.91514409
121* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90765302
122NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.90562290
123PCGF2_27294783_Chip-Seq_NPCs_Mouse0.88090251
124SMC1_22415368_ChIP-Seq_MEFs_Mouse0.85270069
125FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.84579402
126* ISL1_27105846_Chip-Seq_CPCs_Mouse0.83467660
127PCGF2_27294783_Chip-Seq_ESCs_Mouse0.83044258
128SCL_19346495_ChIP-Seq_HPC-7_Human0.82809419

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.09081212
2MP0003705_abnormal_hypodermis_morpholog3.56719209
3MP0005275_abnormal_skin_tensile3.04789918
4MP0003279_aneurysm2.59707998
5MP0004272_abnormal_basement_membrane2.53978817
6MP0003566_abnormal_cell_adhesion2.53640977
7MP0010352_gastrointestinal_tract_polyps2.47749337
8MP0003303_peritoneal_inflammation2.44894630
9MP0003950_abnormal_plasma_membrane2.21110675
10MP0003436_decreased_susceptibility_to2.18873021
11MP0005623_abnormal_meninges_morphology2.07847493
12MP0001879_abnormal_lymphatic_vessel1.97360997
13MP0006054_spinal_hemorrhage1.93487206
14MP0005023_abnormal_wound_healing1.87857619
15MP0001958_emphysema1.87561080
16MP0005503_abnormal_tendon_morphology1.87351927
17MP0010368_abnormal_lymphatic_system1.86831189
18MP0005076_abnormal_cell_differentiation1.86746065
19MP0003191_abnormal_cellular_cholesterol1.75897350
20MP0003724_increased_susceptibility_to1.73900436
21MP0003448_altered_tumor_morphology1.73531963
22MP0003300_gastrointestinal_ulcer1.73224579
23MP0003091_abnormal_cell_migration1.72029747
24MP0003828_pulmonary_edema1.68462405
25MP0001835_abnormal_antigen_presentation1.61689207
26MP0009278_abnormal_bone_marrow1.61643930
27MP0000767_abnormal_smooth_muscle1.61469753
28MP0003941_abnormal_skin_development1.58841882
29MP0001533_abnormal_skeleton_physiology1.51427533
30MP0004510_myositis1.47063134
31MP0002060_abnormal_skin_morphology1.46649609
32MP0000343_altered_response_to1.45813012
33MP0000858_altered_metastatic_potential1.44836223
34MP0009785_altered_susceptibility_to1.43207827
35MP0003453_abnormal_keratinocyte_physiol1.43140138
36MP0002148_abnormal_hypersensitivity_rea1.38934843
37MP0002419_abnormal_innate_immunity1.34865086
38MP0000733_abnormal_muscle_development1.33365717
39MP0000685_abnormal_immune_system1.30200189
40MP0002998_abnormal_bone_remodeling1.29140588
41MP0004947_skin_inflammation1.28370807
42MP0005000_abnormal_immune_tolerance1.28227270
43MP0006082_CNS_inflammation1.27457100
44MP0008004_abnormal_stomach_pH1.25735529
45MP0009053_abnormal_anal_canal1.23449343
46MP0005387_immune_system_phenotype1.22143815
47MP0001790_abnormal_immune_system1.22143815
48MP0002166_altered_tumor_susceptibility1.21143649
49MP0005390_skeleton_phenotype1.19901297
50MP0003763_abnormal_thymus_physiology1.16345664
51MP0002006_tumorigenesis1.15750730
52MP0005595_abnormal_vascular_smooth1.15484397
53MP0009384_cardiac_valve_regurgitation1.14501437
54MP0005257_abnormal_intraocular_pressure1.13489845
55MP0002452_abnormal_antigen_presenting1.13277873
56MP0005025_abnormal_response_to1.12597441
57MP0001542_abnormal_bone_strength1.12133887
58MP0002405_respiratory_system_inflammati1.11342464
59MP0004084_abnormal_cardiac_muscle1.11287559
60MP0003045_fibrosis1.11192611
61MP0002254_reproductive_system_inflammat1.11059820
62MP0005388_respiratory_system_phenotype1.10601831
63MP0002133_abnormal_respiratory_system1.10601831
64MP0010234_abnormal_vibrissa_follicle1.10275590
65MP0005508_abnormal_skeleton_morphology1.07766251
66MP0001853_heart_inflammation1.06454668
67MP0002295_abnormal_pulmonary_circulatio1.05684627
68MP0005164_abnormal_response_to1.04950546
69MP0001243_abnormal_dermal_layer1.03932006
70MP0005367_renal/urinary_system_phenotyp1.01936996
71MP0000516_abnormal_urinary_system1.01936996
72MP0000750_abnormal_muscle_regeneration0.99752635
73MP0000249_abnormal_blood_vessel0.99268138
74MP0001915_intracranial_hemorrhage0.98599123
75MP0005397_hematopoietic_system_phenotyp0.97912017
76MP0001545_abnormal_hematopoietic_system0.97912017
77MP0002933_joint_inflammation0.97727917
78MP0002282_abnormal_trachea_morphology0.97195212
79MP0004808_abnormal_hematopoietic_stem0.97113652
80MP0002108_abnormal_muscle_morphology0.96611047
81MP0003385_abnormal_body_wall0.95680425
82MP0002128_abnormal_blood_circulation0.95200341
83MP0008260_abnormal_autophagy0.94012233
84MP0002896_abnormal_bone_mineralization0.93212370
85MP0008775_abnormal_heart_ventricle0.92879544
86MP0000465_gastrointestinal_hemorrhage0.91374966
87MP0010030_abnormal_orbit_morphology0.91340812
88MP0001614_abnormal_blood_vessel0.90034851
89MP0001849_ear_inflammation0.88591146
90MP0005058_abnormal_lysosome_morphology0.88463679
91MP0004883_abnormal_blood_vessel0.87897152
92MP0001800_abnormal_humoral_immune0.87709549
93MP0002877_abnormal_melanocyte_morpholog0.87488993
94MP0002925_abnormal_cardiovascular_devel0.87386980
95MP0001819_abnormal_immune_cell0.86946806
96MP0002723_abnormal_immune_serum0.86946014
97MP0010155_abnormal_intestine_physiology0.86471501
98MP0010630_abnormal_cardiac_muscle0.86126166
99MP0002420_abnormal_adaptive_immunity0.85189250
100MP0005464_abnormal_platelet_physiology0.85112547
101MP0001851_eye_inflammation0.84443587
102MP0002796_impaired_skin_barrier0.84203381
103MP0002138_abnormal_hepatobiliary_system0.83303330
104MP0006138_congestive_heart_failure0.82338890
105MP0001845_abnormal_inflammatory_respons0.82037903
106MP0009764_decreased_sensitivity_to0.81521490
107MP0004185_abnormal_adipocyte_glucose0.80928813
108MP0003795_abnormal_bone_structure0.78834215
109MP0001216_abnormal_epidermal_layer0.78399768
110MP0003567_abnormal_fetal_cardiomyocyte0.78291331
111MP0009333_abnormal_splenocyte_physiolog0.77681687
112MP0010307_abnormal_tumor_latency0.76830507
113MP0002009_preneoplasia0.75014484
114MP0005671_abnormal_response_to0.74364531
115MP0005197_abnormal_uvea_morphology0.74242878
116MP0000569_abnormal_digit_pigmentation0.72861082
117MP0002113_abnormal_skeleton_development0.72519038
118MP0004130_abnormal_muscle_cell0.72062637
119MP0005409_darkened_coat_color0.71012437
120MP0005165_increased_susceptibility_to0.70973586
121MP0009250_abnormal_appendicular_skeleto0.68168627

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.90860013
2Premature rupture of membranes (HP:0001788)4.76116645
3Eczematoid dermatitis (HP:0000976)3.88437686
4Peritonitis (HP:0002586)3.42053148
5Atrophic scars (HP:0001075)3.41623895
6Aortic dissection (HP:0002647)3.30217589
7Cerebral aneurysm (HP:0004944)3.28259471
8Aortic aneurysm (HP:0004942)3.17367731
9Recurrent abscess formation (HP:0002722)3.13069984
10Osteolytic defects of the hand bones (HP:0009699)3.08739261
11Osteolytic defects of the phalanges of the hand (HP:0009771)3.08739261
12Shallow orbits (HP:0000586)3.05107381
13Vertebral compression fractures (HP:0002953)3.05090223
14Hematochezia (HP:0002573)3.03975125
15Myocardial infarction (HP:0001658)3.01174055
16Increased connective tissue (HP:0009025)2.87648269
17Ankle contracture (HP:0006466)2.83194611
18Dilatation of the ascending aorta (HP:0005111)2.78549688
19Cervical subluxation (HP:0003308)2.75095818
20Soft skin (HP:0000977)2.69706694
21Recurrent bacterial skin infections (HP:0005406)2.65003427
22Fragile skin (HP:0001030)2.64462815
23Mitral valve prolapse (HP:0001634)2.62830959
24Recurrent gram-negative bacterial infections (HP:0005420)2.53128444
25Thick nail (HP:0001805)2.52557743
26Syringomyelia (HP:0003396)2.51546511
27Spinal cord lesions (HP:0100561)2.51546511
28Broad metatarsal (HP:0001783)2.50557031
29T lymphocytopenia (HP:0005403)2.44772010
30Abnormality of T cell number (HP:0011839)2.40056413
31Optic neuritis (HP:0100653)2.37577108
32Retrobulbar optic neuritis (HP:0100654)2.37577108
33Right ventricular cardiomyopathy (HP:0011663)2.35290341
34Asymmetry of the thorax (HP:0001555)2.29180498
35Interstitial pulmonary disease (HP:0006530)2.28865073
36Wormian bones (HP:0002645)2.28653058
37Persistence of primary teeth (HP:0006335)2.28422010
38Spontaneous hematomas (HP:0007420)2.27024344
39Increased density of long bones (HP:0006392)2.25207894
40Subacute progressive viral hepatitis (HP:0006572)2.23046213
41Blue sclerae (HP:0000592)2.22200273
42Abnormality of macrophages (HP:0004311)2.21391650
43Spinal rigidity (HP:0003306)2.19090691
44Wrist flexion contracture (HP:0001239)2.18996024
45Genu recurvatum (HP:0002816)2.17796384
46Camptodactyly of toe (HP:0001836)2.16456033
47Mediastinal lymphadenopathy (HP:0100721)2.14322850
48Short nail (HP:0001799)2.12321089
49Vascular tortuosity (HP:0004948)2.11471831
50Joint laxity (HP:0001388)2.10755154
51Neonatal short-limb short stature (HP:0008921)2.05805292
52Thin bony cortex (HP:0002753)2.04667652
53Gingivitis (HP:0000230)2.03467605
54Esophageal varix (HP:0002040)2.03083639
55Myositis (HP:0100614)2.02089527
56Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.99950900
57Stomatitis (HP:0010280)1.98440900
58Delayed closure of the anterior fontanelle (HP:0001476)1.97279781
59Aneurysm (HP:0002617)1.96883822
60Abnormality of the peritoneum (HP:0002585)1.96868722
61Gastrointestinal infarctions (HP:0005244)1.96206351
62Dislocated radial head (HP:0003083)1.95322849
63Thoracolumbar scoliosis (HP:0002944)1.95228827
64Spondylolisthesis (HP:0003302)1.94985784
65Arterial tortuosity (HP:0005116)1.94949060
66Disproportionate tall stature (HP:0001519)1.94643447
67Hypoplasia of the iris (HP:0007676)1.94229008
68Bicuspid aortic valve (HP:0001647)1.91156702
69Elevated erythrocyte sedimentation rate (HP:0003565)1.90725540
70Bladder diverticulum (HP:0000015)1.90553681
71Nephritis (HP:0000123)1.90343892
72Narrow palate (HP:0000189)1.90140790
73Orchitis (HP:0100796)1.89983271
74Joint contractures involving the joints of the feet (HP:0100492)1.89757615
75Flexion contracture of toe (HP:0005830)1.89757615
76Aortic valve stenosis (HP:0001650)1.89435847
77Autoimmune thrombocytopenia (HP:0001973)1.87657239
78Abnormal hemoglobin (HP:0011902)1.87039035
79Amyloidosis (HP:0011034)1.86666671
80Radial bowing (HP:0002986)1.86513622
81Follicular hyperkeratosis (HP:0007502)1.86229748
82Pulmonary infiltrates (HP:0002113)1.85734294
83Keratoconjunctivitis sicca (HP:0001097)1.85083643
84Alopecia of scalp (HP:0002293)1.85048500
85Cellulitis (HP:0100658)1.84763379
86Elbow flexion contracture (HP:0002987)1.84648068
87Increased variability in muscle fiber diameter (HP:0003557)1.83965296
88Slender build (HP:0001533)1.81140387
89Abnormality of the radial head (HP:0003995)1.81054995
90Aortic regurgitation (HP:0001659)1.80825146
91Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.80689420
92Axonal loss (HP:0003447)1.80154897
93Wide anterior fontanel (HP:0000260)1.79759509
94Abnormality of skull ossification (HP:0002703)1.78907911
95Abnormality of the vasculature of the conjunctiva (HP:0008054)1.78695776
96Delayed cranial suture closure (HP:0000270)1.78474159
97Flared iliac wings (HP:0002869)1.76783342
98Biconcave vertebral bodies (HP:0004586)1.76027612
99Venous abnormality (HP:0002624)1.75093985
100Distal lower limb amyotrophy (HP:0008944)1.74872837
101Type 1 muscle fiber predominance (HP:0003803)1.74646518
102Tetraparesis (HP:0002273)1.74452600
103Abnormality of the frontal sinuses (HP:0002687)1.74340859
104Overgrowth (HP:0001548)1.73957441
105Mitral regurgitation (HP:0001653)1.73228404
106Increased cerebral lipofuscin (HP:0011813)1.72801093
107Systemic lupus erythematosus (HP:0002725)1.71415976
108Increased mean platelet volume (HP:0011877)1.71401694
109Abnormality of skeletal muscle fiber size (HP:0012084)1.71082518
110Conjunctival telangiectasia (HP:0000524)1.71021128
111Decreased skull ossification (HP:0004331)1.69033619
112Recurrent fungal infections (HP:0002841)1.68548608
113Ovoid vertebral bodies (HP:0003300)1.68340604
114Absent frontal sinuses (HP:0002688)1.68083226
115Chronic obstructive pulmonary disease (HP:0006510)1.67800740
116Obstructive lung disease (HP:0006536)1.67800740
117Broad ribs (HP:0000885)1.67315545
118Ectopia lentis (HP:0001083)1.66790476
119Abnormal platelet volume (HP:0011876)1.66716785
120Vacuolated lymphocytes (HP:0001922)1.66167887
121Porencephaly (HP:0002132)1.65894125
122Abnormality of dentin (HP:0010299)1.65781455
123Milia (HP:0001056)1.65620522
124Fused cervical vertebrae (HP:0002949)1.64992216
125Hemoptysis (HP:0002105)1.64540427
126Ulnar bowing (HP:0003031)1.64006098
127Osteomyelitis (HP:0002754)1.62968328
128Joint stiffness (HP:0001387)1.62487681
129Striae distensae (HP:0001065)1.61403373
130Pustule (HP:0200039)1.60607742
131Disinhibition (HP:0000734)1.60232866
132Rectal prolapse (HP:0002035)1.59478658
133Pulmonary artery stenosis (HP:0004415)1.59410000
134Arterial thrombosis (HP:0004420)1.59244357
135Long eyelashes (HP:0000527)1.59151172
136Cupped ribs (HP:0000887)1.59032897
137Coronal craniosynostosis (HP:0004440)1.58325519
138Asymmetric septal hypertrophy (HP:0001670)1.58050581
139Abnormality of the pericardium (HP:0001697)1.58038686
140Hyperextensible skin (HP:0000974)1.57925607
141Recurrent skin infections (HP:0001581)1.57547242
142Abnormality of the distal phalanges of the toes (HP:0010182)1.56632188
143Mesomelia (HP:0003027)1.55226024

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB32.59137675
2TTN2.54587157
3ERN12.30885307
4NEK92.28590317
5MAP3K142.13056754
6TGFBR22.10714621
7MAP3K102.07546169
8STK101.97897290
9PIM21.97693437
10PKN21.96843083
11TBK11.96515987
12KDR1.94720496
13RPS6KA41.84873806
14MAP3K131.82197607
15LRRK21.80848339
16RIPK11.70715172
17BLK1.70449873
18JAK31.67603389
19PDGFRA1.63598618
20EPHB21.60801508
21TESK11.58533679
22PBK1.57562877
23GRK71.56811017
24NME21.56319745
25AKT31.56015271
26TYK21.54608669
27EPHA31.52039768
28TNIK1.51909597
29PTK61.50818878
30TRPM71.48448549
31MAP3K61.48130874
32FGFR41.47689213
33DDR21.46583043
34EPHB11.43774873
35FGFR31.43006056
36LATS11.42946543
37TIE11.42796966
38MAP3K31.41176621
39FER1.39682167
40DMPK1.35664497
41TXK1.35575985
42CDK61.34263660
43IRAK41.33898505
44PRPF4B1.29805625
45FGR1.26216634
46PAK41.25048196
47MAP2K31.24974030
48JAK11.24664779
49PIK3CG1.22892180
50BMX1.22609387
51TGFBR11.21482189
52STK31.20318373
53PTK21.20092588
54MAP4K11.18328307
55CSK1.16225494
56FES1.15351142
57MAPK71.15206892
58CDC42BPA1.13649713
59EPHA21.12538747
60PIK3CA1.09539507
61ZAP701.08491026
62MARK31.05564335
63IKBKE1.04267721
64PRKD21.00522540
65TYRO31.00310223
66LATS20.95976658
67IKBKB0.95007396
68MAP3K110.92781720
69NLK0.91565878
70LIMK10.91290495
71KIT0.91182583
72PAK20.90600818
73IRAK30.90178641
74MST1R0.89386196
75MELK0.88767444
76CHUK0.87925025
77MST40.87505364
78PDGFRB0.84420600
79MAP3K120.82958160
80RIPK40.81007734
81PTK2B0.80686267
82WNK10.79677972
83PIM10.79247195
84HCK0.78137716
85SIK10.77826077
86STK380.76150375
87CDK120.74800638
88ABL20.74473690
89MAP3K70.73116335
90GRK60.71451027
91YES10.69233373
92ERBB40.68282853
93STK240.67560098
94DYRK1B0.66456597
95MARK20.65862546
96SGK30.64990789
97MOS0.63621008
98EGFR0.63556186
99RET0.62608201
100MAP3K80.62263518
101MAPKAPK30.62171541
102BTK0.61411920
103ILK0.60623152
104ERBB30.60595268
105NUAK10.59988028
106ITK0.59969894
107LCK0.59501283
108CAMK1D0.59196627
109ABL10.58832698
110RPS6KC10.58760089
111RPS6KL10.58760089
112MYLK0.58513071
113STK38L0.58258565
114IRAK10.57984111
115MAPKAPK20.56669624
116MET0.56131926
117PRKG20.55890315
118FLT30.54484485
119RPS6KA20.54006992
120MAP3K10.53373831
121STK40.53071613
122TEC0.52829889
123PRKD10.52366733
124MAPK120.51330862
125FRK0.50926098
126INSR0.50761282
127FGFR10.49545526
128CSF1R0.48527611
129SCYL20.48473480
130DAPK30.47538844
131MTOR0.46720636
132MAP3K50.46529424
133JAK20.45724767
134ROCK10.44243666
135MATK0.43609730

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.52018272
2Adherens junction_Homo sapiens_hsa045202.07623128
3Malaria_Homo sapiens_hsa051442.07162706
4ECM-receptor interaction_Homo sapiens_hsa045122.06234452
5Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.98522700
6AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.95151502
7Osteoclast differentiation_Homo sapiens_hsa043801.92466406
8Leukocyte transendothelial migration_Homo sapiens_hsa046701.88958113
9Focal adhesion_Homo sapiens_hsa045101.86361879
10Viral myocarditis_Homo sapiens_hsa054161.85993940
11Toxoplasmosis_Homo sapiens_hsa051451.81385942
12Proteoglycans in cancer_Homo sapiens_hsa052051.80700941
13Toll-like receptor signaling pathway_Homo sapiens_hsa046201.80416020
14Small cell lung cancer_Homo sapiens_hsa052221.75081412
15Amoebiasis_Homo sapiens_hsa051461.73190836
16Shigellosis_Homo sapiens_hsa051311.69759659
17Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.69152522
18NF-kappa B signaling pathway_Homo sapiens_hsa040641.68310236
19Staphylococcus aureus infection_Homo sapiens_hsa051501.66165545
20Pertussis_Homo sapiens_hsa051331.63429027
21TNF signaling pathway_Homo sapiens_hsa046681.63226888
22Salmonella infection_Homo sapiens_hsa051321.62394966
23Legionellosis_Homo sapiens_hsa051341.56775348
24Graft-versus-host disease_Homo sapiens_hsa053321.53772868
25Chronic myeloid leukemia_Homo sapiens_hsa052201.52267957
26Measles_Homo sapiens_hsa051621.46894237
27Tuberculosis_Homo sapiens_hsa051521.45905236
28Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.42314271
29Apoptosis_Homo sapiens_hsa042101.40455683
30Phagosome_Homo sapiens_hsa041451.37686856
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.33295875
32Antigen processing and presentation_Homo sapiens_hsa046121.32635377
33MicroRNAs in cancer_Homo sapiens_hsa052061.32626696
34NOD-like receptor signaling pathway_Homo sapiens_hsa046211.30591126
35Pancreatic cancer_Homo sapiens_hsa052121.28286557
36Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.25604507
37TGF-beta signaling pathway_Homo sapiens_hsa043501.25038436
38Hematopoietic cell lineage_Homo sapiens_hsa046401.24928222
39Bladder cancer_Homo sapiens_hsa052191.23604638
40Regulation of actin cytoskeleton_Homo sapiens_hsa048101.19960625
41Hepatitis B_Homo sapiens_hsa051611.19292471
42Platelet activation_Homo sapiens_hsa046111.16928875
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.14024991
44Jak-STAT signaling pathway_Homo sapiens_hsa046301.13729737
45Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.12296662
46Other glycan degradation_Homo sapiens_hsa005111.11276814
47Acute myeloid leukemia_Homo sapiens_hsa052211.11103196
48Influenza A_Homo sapiens_hsa051641.10212982
49Rheumatoid arthritis_Homo sapiens_hsa053231.08574699
50Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.07959225
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.05496089
52Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.05289935
53Allograft rejection_Homo sapiens_hsa053301.04720885
54B cell receptor signaling pathway_Homo sapiens_hsa046621.04430423
55p53 signaling pathway_Homo sapiens_hsa041151.01013730
56Prostate cancer_Homo sapiens_hsa052150.97435569
57Hippo signaling pathway_Homo sapiens_hsa043900.97301676
58Lysosome_Homo sapiens_hsa041420.96934243
59Chemokine signaling pathway_Homo sapiens_hsa040620.96331380
60HIF-1 signaling pathway_Homo sapiens_hsa040660.95300911
61HTLV-I infection_Homo sapiens_hsa051660.95211141
62Herpes simplex infection_Homo sapiens_hsa051680.94264064
63Thyroid cancer_Homo sapiens_hsa052160.94101153
64Pathways in cancer_Homo sapiens_hsa052000.94074208
65Intestinal immune network for IgA production_Homo sapiens_hsa046720.92559782
66Dilated cardiomyopathy_Homo sapiens_hsa054140.92097889
67Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.90666292
68Melanoma_Homo sapiens_hsa052180.90541775
69PI3K-Akt signaling pathway_Homo sapiens_hsa041510.89330726
70Rap1 signaling pathway_Homo sapiens_hsa040150.88177225
71Non-small cell lung cancer_Homo sapiens_hsa052230.85907584
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84767441
73Complement and coagulation cascades_Homo sapiens_hsa046100.84335390
74Hepatitis C_Homo sapiens_hsa051600.84053837
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.80373838
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.79361684
77VEGF signaling pathway_Homo sapiens_hsa043700.78639561
78Renal cell carcinoma_Homo sapiens_hsa052110.78598370
79MAPK signaling pathway_Homo sapiens_hsa040100.77414901
80Viral carcinogenesis_Homo sapiens_hsa052030.77283487
81Asthma_Homo sapiens_hsa053100.76822163
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76164091
83Ras signaling pathway_Homo sapiens_hsa040140.75179348
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.75032742
85Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74200384
86Endocytosis_Homo sapiens_hsa041440.73646096
87Colorectal cancer_Homo sapiens_hsa052100.73190111
88Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.71899570
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.70730065
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.68997051
91T cell receptor signaling pathway_Homo sapiens_hsa046600.68294999
92Tight junction_Homo sapiens_hsa045300.66228574
93Dorso-ventral axis formation_Homo sapiens_hsa043200.66071912
94Prolactin signaling pathway_Homo sapiens_hsa049170.65744064
95Autoimmune thyroid disease_Homo sapiens_hsa053200.62951656
96Endometrial cancer_Homo sapiens_hsa052130.62112990
97FoxO signaling pathway_Homo sapiens_hsa040680.61337622
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61282119
99Glioma_Homo sapiens_hsa052140.58860710
100Notch signaling pathway_Homo sapiens_hsa043300.58755410
101African trypanosomiasis_Homo sapiens_hsa051430.58755092
102Wnt signaling pathway_Homo sapiens_hsa043100.58247745
103Insulin resistance_Homo sapiens_hsa049310.57672883
104Basal cell carcinoma_Homo sapiens_hsa052170.57217124
105Hedgehog signaling pathway_Homo sapiens_hsa043400.56019604
106Prion diseases_Homo sapiens_hsa050200.55770910
107Choline metabolism in cancer_Homo sapiens_hsa052310.55674971
108Epstein-Barr virus infection_Homo sapiens_hsa051690.52785775
109Central carbon metabolism in cancer_Homo sapiens_hsa052300.51417701
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.48891545
111Protein digestion and absorption_Homo sapiens_hsa049740.47700231
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.47595734

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