

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.33534984 |
| 2 | response to peptidoglycan (GO:0032494) | 6.30079986 |
| 3 | modulation by symbiont of host immune response (GO:0052553) | 5.84273624 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 5.84273624 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 5.84273624 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.84273624 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.84273624 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.84273624 |
| 9 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.45860127 |
| 10 | detection of molecule of bacterial origin (GO:0032490) | 5.43202240 |
| 11 | cellular extravasation (GO:0045123) | 5.22516802 |
| 12 | negative regulation of interleukin-12 production (GO:0032695) | 5.16970654 |
| 13 | neutrophil activation involved in immune response (GO:0002283) | 4.95928205 |
| 14 | macrophage activation involved in immune response (GO:0002281) | 4.82910805 |
| 15 | microglial cell activation (GO:0001774) | 4.78211426 |
| 16 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.58819033 |
| 17 | negative regulation of cell killing (GO:0031342) | 4.58819033 |
| 18 | regulation of gamma-delta T cell activation (GO:0046643) | 4.55494994 |
| 19 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.55105756 |
| 20 | neutrophil mediated immunity (GO:0002446) | 4.44906582 |
| 21 | detection of other organism (GO:0098543) | 4.23797260 |
| 22 | macrophage activation (GO:0042116) | 4.23440268 |
| 23 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.22227729 |
| 24 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.19660749 |
| 25 | neutrophil activation (GO:0042119) | 4.19537780 |
| 26 | response to host immune response (GO:0052572) | 4.18247132 |
| 27 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.18247132 |
| 28 | detection of external biotic stimulus (GO:0098581) | 4.13657951 |
| 29 | response to muramyl dipeptide (GO:0032495) | 4.01747512 |
| 30 | response to host (GO:0075136) | 3.95228287 |
| 31 | response to host defenses (GO:0052200) | 3.95228287 |
| 32 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.95228287 |
| 33 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.91406170 |
| 34 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.89236997 |
| 35 | detection of biotic stimulus (GO:0009595) | 3.83926422 |
| 36 | positive regulation of mast cell activation (GO:0033005) | 3.82253496 |
| 37 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.73123975 |
| 38 | respiratory burst (GO:0045730) | 3.71850059 |
| 39 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.71775723 |
| 40 | granulocyte activation (GO:0036230) | 3.70531432 |
| 41 | myeloid leukocyte mediated immunity (GO:0002444) | 3.67324486 |
| 42 | regulation of mast cell degranulation (GO:0043304) | 3.64150311 |
| 43 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.62884710 |
| 44 | leukocyte aggregation (GO:0070486) | 3.55871736 |
| 45 | regulation of macrophage cytokine production (GO:0010935) | 3.55700132 |
| 46 | T-helper 1 type immune response (GO:0042088) | 3.54293139 |
| 47 | negative regulation of T cell mediated immunity (GO:0002710) | 3.53550793 |
| 48 | detection of bacterium (GO:0016045) | 3.51128646 |
| 49 | sequestering of actin monomers (GO:0042989) | 3.49770724 |
| 50 | regulation of mast cell activation (GO:0033003) | 3.44894302 |
| 51 | myeloid cell activation involved in immune response (GO:0002275) | 3.44611823 |
| 52 | energy homeostasis (GO:0097009) | 3.43463855 |
| 53 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.41508370 |
| 54 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.41384167 |
| 55 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.40252766 |
| 56 | negative regulation of interleukin-6 production (GO:0032715) | 3.36471026 |
| 57 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.34636725 |
| 58 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.34396765 |
| 59 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.33466571 |
| 60 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.33411154 |
| 61 | positive regulation of mast cell degranulation (GO:0043306) | 3.33411154 |
| 62 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.32783438 |
| 63 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.30749374 |
| 64 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.29902335 |
| 65 | neutrophil chemotaxis (GO:0030593) | 3.27242613 |
| 66 | positive thymic T cell selection (GO:0045059) | 3.22657621 |
| 67 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.20524809 |
| 68 | neutrophil migration (GO:1990266) | 3.19416361 |
| 69 | defense response to protozoan (GO:0042832) | 3.18170054 |
| 70 | B cell receptor signaling pathway (GO:0050853) | 3.17120027 |
| 71 | positive regulation of tolerance induction (GO:0002645) | 3.11243209 |
| 72 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.09556264 |
| 73 | germinal center formation (GO:0002467) | 3.06374132 |
| 74 | regulation of leukocyte degranulation (GO:0043300) | 3.05547944 |
| 75 | regulation of tolerance induction (GO:0002643) | 3.03710476 |
| 76 | negative thymic T cell selection (GO:0045060) | 3.03624233 |
| 77 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.03499930 |
| 78 | regulation of B cell differentiation (GO:0045577) | 3.03233258 |
| 79 | negative regulation of interleukin-1 production (GO:0032692) | 3.00106099 |
| 80 | tolerance induction (GO:0002507) | 2.98978469 |
| 81 | superoxide anion generation (GO:0042554) | 2.98613613 |
| 82 | activated T cell proliferation (GO:0050798) | 2.98195730 |
| 83 | dopaminergic neuron differentiation (GO:0071542) | 2.98172957 |
| 84 | positive regulation of interferon-alpha production (GO:0032727) | 2.97792935 |
| 85 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.95757516 |
| 86 | interferon-gamma production (GO:0032609) | 2.94655030 |
| 87 | immunoglobulin mediated immune response (GO:0016064) | 2.94463601 |
| 88 | positive regulation of B cell differentiation (GO:0045579) | 2.92983949 |
| 89 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.92205806 |
| 90 | negative T cell selection (GO:0043383) | 2.89913406 |
| 91 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.88754353 |
| 92 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.88596793 |
| 93 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.88409520 |
| 94 | response to protozoan (GO:0001562) | 2.86832962 |
| 95 | negative regulation of interleukin-17 production (GO:0032700) | 2.84356123 |
| 96 | myeloid leukocyte activation (GO:0002274) | 2.82871349 |
| 97 | dendritic cell migration (GO:0036336) | 2.80975947 |
| 98 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.80124135 |
| 99 | regulation of toll-like receptor signaling pathway (GO:0034121) | 2.79693825 |
| 100 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.78496585 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.67566038 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.31169559 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.11851197 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.10833338 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.91141608 |
| 6 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.32803068 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.24388956 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.23355020 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.20780231 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.08434649 |
| 11 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.84396366 |
| 12 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.77558796 |
| 13 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.72780280 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.68974568 |
| 15 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.58923277 |
| 16 | GATA1_22025678_ChIP-Seq_K562_Human | 2.57147658 |
| 17 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.51195006 |
| 18 | SPI1_23127762_ChIP-Seq_K562_Human | 2.44692770 |
| 19 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.32800749 |
| 20 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 2.29947270 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.28439974 |
| 22 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.27909969 |
| 23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.22985096 |
| 24 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.11056663 |
| 25 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.07090896 |
| 26 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.04752820 |
| 27 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.92078461 |
| 28 | MYB_26560356_Chip-Seq_TH2_Human | 1.86496168 |
| 29 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.83540142 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.81629500 |
| 31 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.74704247 |
| 32 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.74629417 |
| 33 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.69134217 |
| 34 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.61752694 |
| 35 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.61070994 |
| 36 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.59872429 |
| 37 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.56510597 |
| 38 | GATA3_26560356_Chip-Seq_TH2_Human | 1.49443865 |
| 39 | MAF_26560356_Chip-Seq_TH1_Human | 1.48521293 |
| 40 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.43361927 |
| 41 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.41662238 |
| 42 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.40343991 |
| 43 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.40089869 |
| 44 | MYB_26560356_Chip-Seq_TH1_Human | 1.36869439 |
| 45 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.34433985 |
| 46 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.34277554 |
| 47 | UTX_26944678_Chip-Seq_JUKART_Human | 1.32420139 |
| 48 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.28327087 |
| 49 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.28039866 |
| 50 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.26484505 |
| 51 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.26317472 |
| 52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.26258856 |
| 53 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.25135836 |
| 54 | GATA1_19941826_ChIP-Seq_K562_Human | 1.24588154 |
| 55 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22792856 |
| 56 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.21216471 |
| 57 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.17218348 |
| 58 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16424001 |
| 59 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.13833958 |
| 60 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.11054780 |
| 61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.10653503 |
| 62 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09175010 |
| 63 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08841547 |
| 64 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.06771640 |
| 65 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.06574386 |
| 66 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06574386 |
| 67 | GATA2_19941826_ChIP-Seq_K562_Human | 1.05935151 |
| 68 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.01163060 |
| 69 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.97222009 |
| 70 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.96597237 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95943854 |
| 72 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.95567802 |
| 73 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.94961372 |
| 74 | MAF_26560356_Chip-Seq_TH2_Human | 0.90290950 |
| 75 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.89137455 |
| 76 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.87374906 |
| 77 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.87023887 |
| 78 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.85936778 |
| 79 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.83594660 |
| 80 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.83466819 |
| 81 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.83394096 |
| 82 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.83372201 |
| 83 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.81815731 |
| 84 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.81020369 |
| 85 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.79978904 |
| 86 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.79456740 |
| 87 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.78542757 |
| 88 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.77804479 |
| 89 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.75953354 |
| 90 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.75388554 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.75222452 |
| 92 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.74751029 |
| 93 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.74221300 |
| 94 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.73678326 |
| 95 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.73033991 |
| 96 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.72246202 |
| 97 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.71575796 |
| 98 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.69713598 |
| 99 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.69192052 |
| 100 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.69133879 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.95119060 |
| 2 | MP0000569_abnormal_digit_pigmentation | 4.93532176 |
| 3 | MP0003303_peritoneal_inflammation | 4.12128243 |
| 4 | MP0003436_decreased_susceptibility_to | 3.66072186 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.47030231 |
| 6 | MP0003828_pulmonary_edema | 3.12953087 |
| 7 | MP0002419_abnormal_innate_immunity | 3.01634176 |
| 8 | MP0001800_abnormal_humoral_immune | 2.63874451 |
| 9 | MP0005025_abnormal_response_to | 2.50802795 |
| 10 | MP0009785_altered_susceptibility_to | 2.46100902 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.40497708 |
| 12 | MP0005671_abnormal_response_to | 2.37638498 |
| 13 | MP0002723_abnormal_immune_serum | 2.35091008 |
| 14 | MP0000685_abnormal_immune_system | 2.34468276 |
| 15 | MP0002452_abnormal_antigen_presenting | 2.32427144 |
| 16 | MP0003300_gastrointestinal_ulcer | 2.27019273 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.21705042 |
| 18 | MP0001819_abnormal_immune_cell | 2.19313161 |
| 19 | MP0002132_abnormal_respiratory_system | 2.08762057 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.06281817 |
| 21 | MP0004381_abnormal_hair_follicle | 2.01096850 |
| 22 | MP0004883_abnormal_blood_vessel | 2.00732761 |
| 23 | MP0009764_decreased_sensitivity_to | 1.97903613 |
| 24 | MP0005387_immune_system_phenotype | 1.91067628 |
| 25 | MP0001790_abnormal_immune_system | 1.91067628 |
| 26 | MP0001533_abnormal_skeleton_physiology | 1.84567500 |
| 27 | MP0003172_abnormal_lysosome_physiology | 1.79546344 |
| 28 | MP0009278_abnormal_bone_marrow | 1.76869769 |
| 29 | MP0008260_abnormal_autophagy | 1.76479887 |
| 30 | MP0002405_respiratory_system_inflammati | 1.73388496 |
| 31 | MP0001346_abnormal_lacrimal_gland | 1.70936383 |
| 32 | MP0000716_abnormal_immune_system | 1.67697586 |
| 33 | MP0002398_abnormal_bone_marrow | 1.60011773 |
| 34 | MP0004808_abnormal_hematopoietic_stem | 1.57706425 |
| 35 | MP0003656_abnormal_erythrocyte_physiolo | 1.55736154 |
| 36 | MP0002277_abnormal_respiratory_mucosa | 1.54469396 |
| 37 | MP0005464_abnormal_platelet_physiology | 1.52797563 |
| 38 | MP0003191_abnormal_cellular_cholesterol | 1.51788093 |
| 39 | MP0001845_abnormal_inflammatory_respons | 1.49528776 |
| 40 | MP0005164_abnormal_response_to | 1.49190829 |
| 41 | MP0006082_CNS_inflammation | 1.45817494 |
| 42 | MP0002396_abnormal_hematopoietic_system | 1.44294794 |
| 43 | MP0000604_amyloidosis | 1.43927804 |
| 44 | MP0003763_abnormal_thymus_physiology | 1.42662453 |
| 45 | MP0000465_gastrointestinal_hemorrhage | 1.39510435 |
| 46 | MP0003329_amyloid_beta_deposits | 1.37423503 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.35770126 |
| 48 | MP0002166_altered_tumor_susceptibility | 1.35276183 |
| 49 | MP0004947_skin_inflammation | 1.30738977 |
| 50 | MP0003646_muscle_fatigue | 1.30467191 |
| 51 | MP0000689_abnormal_spleen_morphology | 1.28727474 |
| 52 | MP0001853_heart_inflammation | 1.28615244 |
| 53 | MP0002653_abnormal_ependyma_morphology | 1.27216937 |
| 54 | MP0002722_abnormal_immune_system | 1.26804749 |
| 55 | MP0002429_abnormal_blood_cell | 1.23731508 |
| 56 | MP0003075_altered_response_to | 1.22859774 |
| 57 | MP0008469_abnormal_protein_level | 1.18567611 |
| 58 | MP0005075_abnormal_melanosome_morpholog | 1.17719782 |
| 59 | MP0005310_abnormal_salivary_gland | 1.14870358 |
| 60 | MP0005397_hematopoietic_system_phenotyp | 1.12923831 |
| 61 | MP0001545_abnormal_hematopoietic_system | 1.12923831 |
| 62 | MP0002009_preneoplasia | 1.11767830 |
| 63 | MP0002998_abnormal_bone_remodeling | 1.11420510 |
| 64 | MP0000343_altered_response_to | 1.10884780 |
| 65 | MP0001851_eye_inflammation | 1.10285192 |
| 66 | MP0000703_abnormal_thymus_morphology | 1.08962255 |
| 67 | MP0000858_altered_metastatic_potential | 1.08177885 |
| 68 | MP0000015_abnormal_ear_pigmentation | 1.08026119 |
| 69 | MP0002006_tumorigenesis | 1.00464373 |
| 70 | MP0005174_abnormal_tail_pigmentation | 0.97124989 |
| 71 | MP0004130_abnormal_muscle_cell | 0.96513436 |
| 72 | MP0008004_abnormal_stomach_pH | 0.93463814 |
| 73 | MP0001324_abnormal_eye_pigmentation | 0.93281107 |
| 74 | MP0003866_abnormal_defecation | 0.93110634 |
| 75 | MP0002735_abnormal_chemical_nociception | 0.88871230 |
| 76 | MP0005167_abnormal_blood-brain_barrier | 0.85818669 |
| 77 | MP0001905_abnormal_dopamine_level | 0.85262039 |
| 78 | MP0005390_skeleton_phenotype | 0.84818385 |
| 79 | MP0002332_abnormal_exercise_endurance | 0.84481070 |
| 80 | MP0003448_altered_tumor_morphology | 0.83197427 |
| 81 | MP0005084_abnormal_gallbladder_morpholo | 0.82952903 |
| 82 | MP0001663_abnormal_digestive_system | 0.77846873 |
| 83 | MP0003091_abnormal_cell_migration | 0.75771783 |
| 84 | MP0005076_abnormal_cell_differentiation | 0.75651892 |
| 85 | MP0002928_abnormal_bile_duct | 0.73891564 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.72533524 |
| 87 | MP0003787_abnormal_imprinting | 0.71055576 |
| 88 | MP0002138_abnormal_hepatobiliary_system | 0.70363274 |
| 89 | MP0000249_abnormal_blood_vessel | 0.70071789 |
| 90 | MP0005166_decreased_susceptibility_to | 0.67042974 |
| 91 | MP0008057_abnormal_DNA_replication | 0.65032328 |
| 92 | MP0005451_abnormal_body_composition | 0.63807947 |
| 93 | MP0005388_respiratory_system_phenotype | 0.63643678 |
| 94 | MP0002133_abnormal_respiratory_system | 0.63643678 |
| 95 | MP0005376_homeostasis/metabolism_phenot | 0.63234958 |
| 96 | MP0002933_joint_inflammation | 0.63074313 |
| 97 | MP0003690_abnormal_glial_cell | 0.62796086 |
| 98 | MP0005535_abnormal_body_temperature | 0.62753257 |
| 99 | MP0003632_abnormal_nervous_system | 0.58926208 |
| 100 | MP0001186_pigmentation_phenotype | 0.57790651 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent bacterial skin infections (HP:0005406) | 6.04890378 |
| 2 | Recurrent abscess formation (HP:0002722) | 5.52803392 |
| 3 | Myositis (HP:0100614) | 5.37073967 |
| 4 | Eczematoid dermatitis (HP:0000976) | 5.27946098 |
| 5 | Stomatitis (HP:0010280) | 5.22570781 |
| 6 | Optic neuritis (HP:0100653) | 5.18613726 |
| 7 | Retrobulbar optic neuritis (HP:0100654) | 5.18613726 |
| 8 | Orchitis (HP:0100796) | 5.05659968 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.01108318 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.87512974 |
| 11 | Recurrent skin infections (HP:0001581) | 4.33681995 |
| 12 | Gastrointestinal infarctions (HP:0005244) | 4.15002113 |
| 13 | Abnormality of macrophages (HP:0004311) | 4.11825070 |
| 14 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.97829213 |
| 15 | Recurrent cutaneous fungal infections (HP:0011370) | 3.97829213 |
| 16 | Recurrent fungal infections (HP:0002841) | 3.93929673 |
| 17 | Encephalitis (HP:0002383) | 3.76998326 |
| 18 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.70557199 |
| 19 | Stomach cancer (HP:0012126) | 3.66487844 |
| 20 | Keratoconjunctivitis sicca (HP:0001097) | 3.65069746 |
| 21 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.43545273 |
| 22 | Viral hepatitis (HP:0006562) | 3.38195115 |
| 23 | Keratoconjunctivitis (HP:0001096) | 3.34413970 |
| 24 | Arterial thrombosis (HP:0004420) | 3.22545604 |
| 25 | Peritonitis (HP:0002586) | 3.15812338 |
| 26 | Subacute progressive viral hepatitis (HP:0006572) | 3.15372415 |
| 27 | Vasculitis (HP:0002633) | 3.12635353 |
| 28 | Mediastinal lymphadenopathy (HP:0100721) | 3.05027428 |
| 29 | Meningitis (HP:0001287) | 3.03453811 |
| 30 | Gingival bleeding (HP:0000225) | 3.03177482 |
| 31 | Episodic fever (HP:0001954) | 2.96387000 |
| 32 | Amyloidosis (HP:0011034) | 2.84585180 |
| 33 | T lymphocytopenia (HP:0005403) | 2.80943069 |
| 34 | Anterior segment dysgenesis (HP:0007700) | 2.80697722 |
| 35 | Leukocytosis (HP:0001974) | 2.79895218 |
| 36 | Obstructive lung disease (HP:0006536) | 2.77515639 |
| 37 | Chronic obstructive pulmonary disease (HP:0006510) | 2.77515639 |
| 38 | Chest pain (HP:0100749) | 2.76134067 |
| 39 | Gingivitis (HP:0000230) | 2.71802167 |
| 40 | Abnormality of T cell number (HP:0011839) | 2.71719077 |
| 41 | Prolonged bleeding time (HP:0003010) | 2.67113828 |
| 42 | Hemoptysis (HP:0002105) | 2.64925671 |
| 43 | Polyphagia (HP:0002591) | 2.56506567 |
| 44 | Pulmonary infiltrates (HP:0002113) | 2.53956451 |
| 45 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.53435285 |
| 46 | Alveolar cell carcinoma (HP:0006519) | 2.50680368 |
| 47 | Recurrent viral infections (HP:0004429) | 2.49839997 |
| 48 | Gangrene (HP:0100758) | 2.49346500 |
| 49 | Vertigo (HP:0002321) | 2.48015661 |
| 50 | Colitis (HP:0002583) | 2.45630492 |
| 51 | Epistaxis (HP:0000421) | 2.45076697 |
| 52 | Urticaria (HP:0001025) | 2.42422504 |
| 53 | Panhypogammaglobulinemia (HP:0003139) | 2.40364439 |
| 54 | Cellulitis (HP:0100658) | 2.35925885 |
| 55 | Spontaneous hematomas (HP:0007420) | 2.35674368 |
| 56 | Abnormality of T cells (HP:0002843) | 2.33741257 |
| 57 | Chronic otitis media (HP:0000389) | 2.32996956 |
| 58 | Inflammation of the large intestine (HP:0002037) | 2.32326467 |
| 59 | Increased IgE level (HP:0003212) | 2.27022376 |
| 60 | Supernumerary ribs (HP:0005815) | 2.25929004 |
| 61 | Acute lymphatic leukemia (HP:0006721) | 2.25739193 |
| 62 | Anorexia (HP:0002039) | 2.25462086 |
| 63 | IgM deficiency (HP:0002850) | 2.20171731 |
| 64 | Abnormal drinking behavior (HP:0030082) | 2.18893848 |
| 65 | Polydipsia (HP:0001959) | 2.18893848 |
| 66 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.18850261 |
| 67 | Abnormality of the peritoneum (HP:0002585) | 2.18382288 |
| 68 | Pulmonary embolism (HP:0002204) | 2.14685384 |
| 69 | Slow saccadic eye movements (HP:0000514) | 2.11962136 |
| 70 | Gastrointestinal inflammation (HP:0004386) | 2.10181722 |
| 71 | Thrombocytosis (HP:0001894) | 2.07457445 |
| 72 | Recurrent bronchitis (HP:0002837) | 2.01785616 |
| 73 | Amaurosis fugax (HP:0100576) | 2.00425597 |
| 74 | Muscle fiber splitting (HP:0003555) | 1.96096376 |
| 75 | Exertional dyspnea (HP:0002875) | 1.92467585 |
| 76 | Micronodular cirrhosis (HP:0001413) | 1.91797702 |
| 77 | Abnormality of the pleura (HP:0002103) | 1.90704057 |
| 78 | Increased IgM level (HP:0003496) | 1.89342269 |
| 79 | Abnormality of T cell physiology (HP:0011840) | 1.87529835 |
| 80 | Acute myeloid leukemia (HP:0004808) | 1.85488952 |
| 81 | Polyneuropathy (HP:0001271) | 1.84764954 |
| 82 | Glomerulopathy (HP:0100820) | 1.84405509 |
| 83 | Chronic sinusitis (HP:0011109) | 1.84152422 |
| 84 | Widely spaced teeth (HP:0000687) | 1.84003668 |
| 85 | Abnormality of the parietal bone (HP:0002696) | 1.83026456 |
| 86 | Respiratory difficulties (HP:0002880) | 1.81406535 |
| 87 | Pustule (HP:0200039) | 1.81074691 |
| 88 | Abnormality of the endocardium (HP:0004306) | 1.77669680 |
| 89 | Agammaglobulinemia (HP:0004432) | 1.74458633 |
| 90 | Osteomyelitis (HP:0002754) | 1.73036545 |
| 91 | Concave nail (HP:0001598) | 1.72500334 |
| 92 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.71486022 |
| 93 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.71486022 |
| 94 | Abnormality of glycolipid metabolism (HP:0010969) | 1.71486022 |
| 95 | Granulocytopenia (HP:0001913) | 1.68116108 |
| 96 | Xerostomia (HP:0000217) | 1.67511795 |
| 97 | Eosinophilia (HP:0001880) | 1.63633141 |
| 98 | Short 4th metacarpal (HP:0010044) | 1.63120759 |
| 99 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.63120759 |
| 100 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.62710897 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 3.78686364 |
| 2 | IRAK4 | 3.51013507 |
| 3 | TAOK3 | 3.31639544 |
| 4 | BLK | 2.81592756 |
| 5 | MAP2K3 | 2.59537989 |
| 6 | MAP4K1 | 2.56816888 |
| 7 | MAP3K14 | 2.53157098 |
| 8 | CSK | 2.41836927 |
| 9 | FES | 2.37008840 |
| 10 | IRAK1 | 2.35024182 |
| 11 | TXK | 2.30251667 |
| 12 | TYK2 | 2.28502323 |
| 13 | MAP3K13 | 2.21430630 |
| 14 | IKBKE | 2.10969099 |
| 15 | FGR | 2.06574670 |
| 16 | GRK6 | 2.06561563 |
| 17 | IRAK2 | 2.05043773 |
| 18 | ZAP70 | 1.80980638 |
| 19 | SYK | 1.71626150 |
| 20 | JAK3 | 1.66506359 |
| 21 | KIT | 1.63713549 |
| 22 | TBK1 | 1.61063672 |
| 23 | IRAK3 | 1.53806133 |
| 24 | BTK | 1.51652106 |
| 25 | MATK | 1.49419165 |
| 26 | IKBKB | 1.48974438 |
| 27 | TEC | 1.47862025 |
| 28 | CSF1R | 1.47108522 |
| 29 | HCK | 1.45242702 |
| 30 | BMPR2 | 1.41060303 |
| 31 | JAK1 | 1.37469716 |
| 32 | TLK1 | 1.26115250 |
| 33 | MAP3K3 | 1.25123272 |
| 34 | WNK1 | 1.18272184 |
| 35 | LYN | 1.17112133 |
| 36 | PRPF4B | 1.14037583 |
| 37 | JAK2 | 1.11306110 |
| 38 | MARK3 | 1.09040902 |
| 39 | MAP2K4 | 1.08200287 |
| 40 | MAP3K1 | 1.07539219 |
| 41 | KSR2 | 1.06938834 |
| 42 | SIK1 | 1.06522315 |
| 43 | CHUK | 1.04446266 |
| 44 | LRRK2 | 1.03439235 |
| 45 | LCK | 1.03242247 |
| 46 | ITK | 1.01879293 |
| 47 | MAP3K2 | 1.00804763 |
| 48 | EPHB1 | 0.99168324 |
| 49 | SIK3 | 0.96533952 |
| 50 | PIK3CG | 0.96406411 |
| 51 | TNK2 | 0.96190087 |
| 52 | MARK2 | 0.94830952 |
| 53 | MAP3K11 | 0.94011381 |
| 54 | MAP3K7 | 0.93525645 |
| 55 | GRK7 | 0.89894376 |
| 56 | PINK1 | 0.87536659 |
| 57 | YES1 | 0.82630773 |
| 58 | EPHA3 | 0.82566455 |
| 59 | PTK2B | 0.74898467 |
| 60 | MAP2K6 | 0.74497411 |
| 61 | MAPK7 | 0.68824769 |
| 62 | MAP3K6 | 0.66391541 |
| 63 | PIM1 | 0.64497644 |
| 64 | CDK19 | 0.62833945 |
| 65 | FGFR3 | 0.62435249 |
| 66 | SIK2 | 0.59418981 |
| 67 | NME1 | 0.58152094 |
| 68 | NLK | 0.57939004 |
| 69 | MAPK12 | 0.57788323 |
| 70 | SGK2 | 0.56414133 |
| 71 | RAF1 | 0.55564565 |
| 72 | PDK1 | 0.53725949 |
| 73 | FRK | 0.52872825 |
| 74 | FYN | 0.52637163 |
| 75 | CDK8 | 0.52039288 |
| 76 | MAPK4 | 0.51120362 |
| 77 | DYRK3 | 0.50460204 |
| 78 | DYRK1A | 0.50364262 |
| 79 | PASK | 0.50021962 |
| 80 | KSR1 | 0.49009721 |
| 81 | TAOK1 | 0.47930502 |
| 82 | ERN1 | 0.47081659 |
| 83 | SGK3 | 0.42800256 |
| 84 | DAPK2 | 0.41439149 |
| 85 | CAMK1D | 0.39823020 |
| 86 | PDPK1 | 0.39644724 |
| 87 | RET | 0.39314752 |
| 88 | MAP3K5 | 0.39014161 |
| 89 | CAMK1G | 0.38997183 |
| 90 | CDK12 | 0.38723132 |
| 91 | HIPK2 | 0.36740465 |
| 92 | SGK1 | 0.36520519 |
| 93 | ABL1 | 0.35007530 |
| 94 | PRKCQ | 0.34481959 |
| 95 | DYRK1B | 0.33155072 |
| 96 | ADRBK1 | 0.32849669 |
| 97 | STK11 | 0.31423508 |
| 98 | PNCK | 0.29361110 |
| 99 | MOS | 0.29323362 |
| 100 | RPS6KA6 | 0.29219754 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.09162242 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.90986452 |
| 3 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.68834597 |
| 4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.31912934 |
| 5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.23228651 |
| 6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.18594773 |
| 7 | Tuberculosis_Homo sapiens_hsa05152 | 2.15576657 |
| 8 | Legionellosis_Homo sapiens_hsa05134 | 2.03103240 |
| 9 | Malaria_Homo sapiens_hsa05144 | 2.01552001 |
| 10 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.91902193 |
| 11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.88153951 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.87076445 |
| 13 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.75223200 |
| 14 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.71423909 |
| 15 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.70004626 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.68643651 |
| 17 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.64582908 |
| 18 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.62554573 |
| 19 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.58647803 |
| 20 | Measles_Homo sapiens_hsa05162 | 1.56028837 |
| 21 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.52258186 |
| 22 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.50944627 |
| 23 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.47596425 |
| 24 | Influenza A_Homo sapiens_hsa05164 | 1.44567429 |
| 25 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.42028576 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.39951399 |
| 27 | Hepatitis B_Homo sapiens_hsa05161 | 1.37554630 |
| 28 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.36909442 |
| 29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.33537702 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.31704018 |
| 31 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.30819562 |
| 32 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.28559573 |
| 33 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.28551985 |
| 34 | Pertussis_Homo sapiens_hsa05133 | 1.17354330 |
| 35 | Platelet activation_Homo sapiens_hsa04611 | 1.11193729 |
| 36 | Allograft rejection_Homo sapiens_hsa05330 | 1.10872967 |
| 37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.03102708 |
| 38 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.02220717 |
| 39 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.02124336 |
| 40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.00710960 |
| 41 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.00376584 |
| 42 | Hepatitis C_Homo sapiens_hsa05160 | 1.00142419 |
| 43 | Salmonella infection_Homo sapiens_hsa05132 | 0.98017713 |
| 44 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.97505842 |
| 45 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.97445279 |
| 46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.97149506 |
| 47 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.94785504 |
| 48 | Phagosome_Homo sapiens_hsa04145 | 0.94653013 |
| 49 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.94385171 |
| 50 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.94260234 |
| 51 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.92780524 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.89608275 |
| 53 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.88998854 |
| 54 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.88897859 |
| 55 | Amoebiasis_Homo sapiens_hsa05146 | 0.88511528 |
| 56 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.86779781 |
| 57 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.86547919 |
| 58 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.85443418 |
| 59 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.83433441 |
| 60 | Endometrial cancer_Homo sapiens_hsa05213 | 0.82274737 |
| 61 | Asthma_Homo sapiens_hsa05310 | 0.80904212 |
| 62 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.80506717 |
| 63 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.79225148 |
| 64 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.75733358 |
| 65 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.73332572 |
| 66 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.70740573 |
| 67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.69868773 |
| 68 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.69740715 |
| 69 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.68394581 |
| 70 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.67684227 |
| 71 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.67190513 |
| 72 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64663915 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.64579553 |
| 74 | Prostate cancer_Homo sapiens_hsa05215 | 0.63460593 |
| 75 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.63083293 |
| 76 | Other glycan degradation_Homo sapiens_hsa00511 | 0.62145530 |
| 77 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.60855151 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.59762882 |
| 79 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.56706418 |
| 80 | Colorectal cancer_Homo sapiens_hsa05210 | 0.55903773 |
| 81 | Shigellosis_Homo sapiens_hsa05131 | 0.55174034 |
| 82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.54736296 |
| 83 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.53924129 |
| 84 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.51627212 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50638638 |
| 86 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.49532314 |
| 87 | Insulin resistance_Homo sapiens_hsa04931 | 0.48260320 |
| 88 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.47914495 |
| 89 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.46895634 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.46770092 |
| 91 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.46311661 |
| 92 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.46137001 |
| 93 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.46104156 |
| 94 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.42575397 |
| 95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.40191280 |
| 96 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.38854665 |
| 97 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.37209641 |
| 98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.36425600 |
| 99 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.35558237 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.33897112 |

