Rank | Gene Set | Z-score |
---|---|---|
1 | paraxial mesoderm development (GO:0048339) | 4.30077503 |
2 | protein heterotrimerization (GO:0070208) | 4.24022106 |
3 | pericardium development (GO:0060039) | 3.99810038 |
4 | cell adhesion mediated by integrin (GO:0033627) | 3.81779258 |
5 | glomerular basement membrane development (GO:0032836) | 3.71521916 |
6 | basement membrane organization (GO:0071711) | 3.65368428 |
7 | cardiac myofibril assembly (GO:0055003) | 3.57567132 |
8 | skin morphogenesis (GO:0043589) | 3.56628361 |
9 | mesodermal cell differentiation (GO:0048333) | 3.50738537 |
10 | substrate-dependent cell migration (GO:0006929) | 3.47536458 |
11 | smooth muscle tissue development (GO:0048745) | 3.41856197 |
12 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.41497318 |
13 | hippo signaling (GO:0035329) | 3.39907011 |
14 | chondrocyte proliferation (GO:0035988) | 3.33457221 |
15 | plasma membrane repair (GO:0001778) | 3.27208235 |
16 | regulation of hippo signaling (GO:0035330) | 3.26249856 |
17 | collagen fibril organization (GO:0030199) | 3.25823438 |
18 | artery development (GO:0060840) | 3.25195288 |
19 | bone trabecula formation (GO:0060346) | 3.24013992 |
20 | sarcomere organization (GO:0045214) | 3.21195775 |
21 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.19002570 |
22 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.17426420 |
23 | epithelial cell-cell adhesion (GO:0090136) | 3.16676755 |
24 | regulation of SMAD protein import into nucleus (GO:0060390) | 3.16358596 |
25 | lung vasculature development (GO:0060426) | 3.15085018 |
26 | cellular response to vitamin (GO:0071295) | 3.12996606 |
27 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.09516116 |
28 | surfactant homeostasis (GO:0043129) | 3.08468244 |
29 | sprouting angiogenesis (GO:0002040) | 3.05053121 |
30 | polarized epithelial cell differentiation (GO:0030859) | 3.01172390 |
31 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.99746314 |
32 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.94166657 |
33 | myofibril assembly (GO:0030239) | 2.93331962 |
34 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.93070975 |
35 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.91456146 |
36 | notochord development (GO:0030903) | 2.90500818 |
37 | endodermal cell differentiation (GO:0035987) | 2.89869365 |
38 | muscle filament sliding (GO:0030049) | 2.89164859 |
39 | actin-myosin filament sliding (GO:0033275) | 2.89164859 |
40 | establishment of apical/basal cell polarity (GO:0035089) | 2.88949736 |
41 | axon extension involved in axon guidance (GO:0048846) | 2.87699783 |
42 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.87699783 |
43 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.86748498 |
44 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.86419789 |
45 | regulation of tight junction assembly (GO:2000810) | 2.85508502 |
46 | renal filtration (GO:0097205) | 2.85077116 |
47 | endocardial cushion development (GO:0003197) | 2.85063997 |
48 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.83546634 |
49 | regulation of cardioblast differentiation (GO:0051890) | 2.82666298 |
50 | negative regulation of protein localization to cell surface (GO:2000009) | 2.80608691 |
51 | cell-substrate junction assembly (GO:0007044) | 2.79140216 |
52 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.78444683 |
53 | cellular response to vitamin D (GO:0071305) | 2.78432934 |
54 | glomerular filtration (GO:0003094) | 2.77881012 |
55 | wound healing, spreading of cells (GO:0044319) | 2.75817852 |
56 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.75216843 |
57 | cardiac muscle cell development (GO:0055013) | 2.74468545 |
58 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.71804360 |
59 | type B pancreatic cell proliferation (GO:0044342) | 2.70746075 |
60 | cardiac cell development (GO:0055006) | 2.68868761 |
61 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.68644225 |
62 | embryonic foregut morphogenesis (GO:0048617) | 2.68314166 |
63 | low-density lipoprotein particle clearance (GO:0034383) | 2.67648278 |
64 | hemidesmosome assembly (GO:0031581) | 2.67352626 |
65 | lymph vessel development (GO:0001945) | 2.66418713 |
66 | fibroblast migration (GO:0010761) | 2.65736344 |
67 | muscle cell migration (GO:0014812) | 2.65605897 |
68 | lung lobe morphogenesis (GO:0060463) | 2.65156527 |
69 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 2.65099368 |
70 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.64914604 |
71 | regulation of gene silencing by miRNA (GO:0060964) | 2.64914604 |
72 | regulation of gene silencing by RNA (GO:0060966) | 2.64914604 |
73 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 2.63833748 |
74 | wound healing, spreading of epidermal cells (GO:0035313) | 2.63688192 |
75 | chemical homeostasis within a tissue (GO:0048875) | 2.63668108 |
76 | atrioventricular valve morphogenesis (GO:0003181) | 2.63416658 |
77 | negative regulation of cartilage development (GO:0061037) | 2.63034095 |
78 | apoptotic cell clearance (GO:0043277) | 2.62622044 |
79 | adhesion of symbiont to host cell (GO:0044650) | 2.61788550 |
80 | virion attachment to host cell (GO:0019062) | 2.61788550 |
81 | actin-mediated cell contraction (GO:0070252) | 2.61147610 |
82 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.59774268 |
83 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.59516746 |
84 | glomerular visceral epithelial cell development (GO:0072015) | 2.58400618 |
85 | cell proliferation involved in metanephros development (GO:0072203) | 2.57850739 |
86 | venous blood vessel morphogenesis (GO:0048845) | 2.56348412 |
87 | cell migration involved in heart development (GO:0060973) | 2.56020589 |
88 | adherens junction assembly (GO:0034333) | 2.55458267 |
89 | endothelial cell morphogenesis (GO:0001886) | 2.54281969 |
90 | embryonic camera-type eye development (GO:0031076) | 2.54217591 |
91 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.53494916 |
92 | extracellular matrix assembly (GO:0085029) | 2.52626495 |
93 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.52140938 |
94 | metanephric mesenchyme development (GO:0072075) | 2.51837954 |
95 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.51762755 |
96 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.51271860 |
97 | endothelium development (GO:0003158) | 2.50141855 |
98 | lymphangiogenesis (GO:0001946) | 2.49991125 |
99 | mesenchyme development (GO:0060485) | 2.49934331 |
100 | mesenchymal-epithelial cell signaling (GO:0060638) | 2.48937986 |
101 | anatomical structure regression (GO:0060033) | 2.48170149 |
102 | positive regulation of cartilage development (GO:0061036) | 2.47971061 |
103 | hypotonic response (GO:0006971) | 2.47860531 |
104 | trabecula formation (GO:0060343) | 2.47190293 |
105 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.47101441 |
106 | regulation of G0 to G1 transition (GO:0070316) | 2.46858490 |
107 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 2.46148022 |
108 | desmosome organization (GO:0002934) | 2.45391336 |
109 | kidney mesenchyme development (GO:0072074) | 2.45046436 |
110 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.45007236 |
111 | apoptotic process involved in morphogenesis (GO:0060561) | 2.44594900 |
112 | actomyosin structure organization (GO:0031032) | 2.44449072 |
113 | outer ear morphogenesis (GO:0042473) | 2.43820734 |
114 | response to gravity (GO:0009629) | 2.42950905 |
115 | organ formation (GO:0048645) | 2.42536230 |
116 | regulation of axon guidance (GO:1902667) | 2.42191557 |
117 | regulation of mitotic spindle organization (GO:0060236) | 2.41208974 |
118 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.40465161 |
119 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.40130075 |
120 | muscle cell fate commitment (GO:0042693) | 2.38748372 |
121 | negative regulation of axon guidance (GO:1902668) | 2.38266141 |
122 | neuron remodeling (GO:0016322) | 2.37517238 |
123 | neural crest cell development (GO:0014032) | 2.37388596 |
124 | regulation of heart morphogenesis (GO:2000826) | 2.36842694 |
125 | outflow tract septum morphogenesis (GO:0003148) | 2.36717947 |
126 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.35404672 |
127 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 2.35153342 |
128 | protein hydroxylation (GO:0018126) | 2.34814087 |
129 | regulation of endothelial cell differentiation (GO:0045601) | 2.34660798 |
130 | endocrine hormone secretion (GO:0060986) | 2.34215959 |
131 | regulation of glomerular filtration (GO:0003093) | 2.33330587 |
132 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.33263598 |
133 | positive regulation of osteoblast proliferation (GO:0033690) | 2.31976309 |
134 | negative regulation of Rho protein signal transduction (GO:0035024) | 2.31329114 |
135 | cardiac muscle tissue morphogenesis (GO:0055008) | 2.31190569 |
136 | positive regulation of endothelial cell migration (GO:0010595) | 2.30999101 |
137 | peptidyl-proline hydroxylation (GO:0019511) | 2.30889568 |
138 | protein localization to cell surface (GO:0034394) | 2.30758333 |
139 | collagen metabolic process (GO:0032963) | 2.30509962 |
140 | negative regulation of fatty acid transport (GO:2000192) | 2.30509188 |
141 | maternal placenta development (GO:0001893) | 2.30166518 |
142 | membrane raft organization (GO:0031579) | 2.30146174 |
143 | regulation of integrin activation (GO:0033623) | 2.30031916 |
144 | face morphogenesis (GO:0060325) | 2.29770790 |
145 | cell-substrate adherens junction assembly (GO:0007045) | 2.29707580 |
146 | focal adhesion assembly (GO:0048041) | 2.29707580 |
147 | heart trabecula formation (GO:0060347) | 2.28625285 |
148 | endothelial cell chemotaxis (GO:0035767) | 2.27900551 |
149 | blood vessel endothelial cell migration (GO:0043534) | 2.27772349 |
150 | wound healing (GO:0042060) | 2.27746277 |
151 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.27736584 |
152 | morphogenesis of an endothelium (GO:0003159) | 2.26912312 |
153 | endothelial tube morphogenesis (GO:0061154) | 2.26912312 |
154 | heterochromatin organization (GO:0070828) | 2.26683174 |
155 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.26348155 |
156 | regulation of cartilage development (GO:0061035) | 2.26336744 |
157 | negative regulation of catenin import into nucleus (GO:0035414) | 2.25258157 |
158 | blood vessel maturation (GO:0001955) | 2.23047762 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.76836711 |
2 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.74237358 |
3 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.41536055 |
4 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.40104681 |
5 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.75413951 |
6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.72058136 |
7 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.68315369 |
8 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.62287066 |
9 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.54603032 |
10 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.54603032 |
11 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.54603032 |
12 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.52407843 |
13 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.49366063 |
14 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.34729809 |
15 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.33396154 |
16 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.32984698 |
17 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.28210343 |
18 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.22789369 |
19 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.18262828 |
20 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.09070210 |
21 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.06527172 |
22 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.03711154 |
23 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.01264355 |
24 | TP53_16413492_ChIP-PET_HCT116_Human | 2.00279829 |
25 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.98827555 |
26 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.88673353 |
27 | * TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.87328037 |
28 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.86037192 |
29 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.83621830 |
30 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.83336706 |
31 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.81016721 |
32 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.79930923 |
33 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.76781189 |
34 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.73352853 |
35 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.72749893 |
36 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.70716724 |
37 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.69094229 |
38 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.67151724 |
39 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.67082557 |
40 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.67082557 |
41 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.66588733 |
42 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.66252604 |
43 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.65520915 |
44 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.62816364 |
45 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.61857517 |
46 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.58593207 |
47 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.58011432 |
48 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.58002020 |
49 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.57713099 |
50 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.57713099 |
51 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.57582380 |
52 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.55989081 |
53 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.54047554 |
54 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.53449284 |
55 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.51495192 |
56 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.50101259 |
57 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.49914330 |
58 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.48868499 |
59 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.47789303 |
60 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.46446994 |
61 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.45164980 |
62 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.44701356 |
63 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.44085632 |
64 | ATF3_27146783_Chip-Seq_COLON_Human | 1.43976842 |
65 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.42771793 |
66 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.42724888 |
67 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.42329113 |
68 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.41461930 |
69 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.41413599 |
70 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.40923297 |
71 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.39018421 |
72 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.36927990 |
73 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.35703416 |
74 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.35385542 |
75 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.33922291 |
76 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.33158153 |
77 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.32810958 |
78 | * SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.32741981 |
79 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.32317542 |
80 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.32248505 |
81 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.30506145 |
82 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.29224841 |
83 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.29224841 |
84 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.29163009 |
85 | * TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.29020964 |
86 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.28552991 |
87 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.27491770 |
88 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.27044908 |
89 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26186005 |
90 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.25668796 |
91 | MYC_22102868_ChIP-Seq_BL_Human | 1.24852185 |
92 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.23826304 |
93 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.23653885 |
94 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.23217832 |
95 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.22205442 |
96 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.20765369 |
97 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.20373440 |
98 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.20224616 |
99 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.20161776 |
100 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.20120089 |
101 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.19956376 |
102 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.19759172 |
103 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.19418897 |
104 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.19418897 |
105 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.19390745 |
106 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.18642242 |
107 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.18087100 |
108 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.17978035 |
109 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.16677731 |
110 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.16515634 |
111 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.16243800 |
112 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.15870186 |
113 | RXR_22108803_ChIP-Seq_LS180_Human | 1.15005312 |
114 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.14677410 |
115 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.13987276 |
116 | * FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.13748270 |
117 | CJUN_26792858_Chip-Seq_BT549_Human | 1.13641812 |
118 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.13232788 |
119 | * GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.12038189 |
120 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.10979011 |
121 | * SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.10548586 |
122 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.10349940 |
123 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.08341117 |
124 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.07892556 |
125 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.07874330 |
126 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.07644996 |
127 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.07234668 |
128 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.06693709 |
129 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.06181362 |
130 | * NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.05831547 |
131 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.04389489 |
132 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.04278683 |
133 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.03432825 |
134 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.03119122 |
135 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.02748945 |
136 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.02716483 |
137 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.02597460 |
138 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.02148072 |
139 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.01956221 |
140 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.01726174 |
141 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.01665297 |
142 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.01527345 |
143 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.01338710 |
144 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.00681928 |
145 | STAT3_23295773_ChIP-Seq_U87_Human | 1.00387979 |
146 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.99851651 |
147 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.99778068 |
148 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.98751095 |
149 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.98668646 |
150 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.98663260 |
151 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.98075220 |
152 | * NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.97683978 |
153 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.97066477 |
154 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.97056045 |
155 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97010755 |
156 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.96651066 |
157 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.95556998 |
158 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.95151853 |
159 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.92172304 |
160 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.91675048 |
161 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.90062387 |
162 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.90048625 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 4.61351091 |
2 | MP0005275_abnormal_skin_tensile | 3.09148747 |
3 | MP0003705_abnormal_hypodermis_morpholog | 3.02181790 |
4 | MP0005503_abnormal_tendon_morphology | 2.87310435 |
5 | MP0004272_abnormal_basement_membrane | 2.64720275 |
6 | MP0000013_abnormal_adipose_tissue | 2.36237963 |
7 | MP0004084_abnormal_cardiac_muscle | 2.35452269 |
8 | MP0010030_abnormal_orbit_morphology | 2.32650357 |
9 | MP0003279_aneurysm | 2.30831566 |
10 | MP0003566_abnormal_cell_adhesion | 2.15200104 |
11 | MP0005623_abnormal_meninges_morphology | 2.10083325 |
12 | MP0009780_abnormal_chondrocyte_physiolo | 2.07611254 |
13 | MP0010368_abnormal_lymphatic_system | 2.00781924 |
14 | MP0001542_abnormal_bone_strength | 1.91765913 |
15 | MP0005595_abnormal_vascular_smooth | 1.78024985 |
16 | MP0003828_pulmonary_edema | 1.71200635 |
17 | MP0010352_gastrointestinal_tract_polyps | 1.69440405 |
18 | MP0000750_abnormal_muscle_regeneration | 1.68032549 |
19 | MP0003941_abnormal_skin_development | 1.64435110 |
20 | MP0005670_abnormal_white_adipose | 1.59453550 |
21 | MP0001958_emphysema | 1.57494466 |
22 | MP0003567_abnormal_fetal_cardiomyocyte | 1.53958361 |
23 | MP0005508_abnormal_skeleton_morphology | 1.53633619 |
24 | MP0010630_abnormal_cardiac_muscle | 1.52529950 |
25 | MP0008775_abnormal_heart_ventricle | 1.50409780 |
26 | MP0009384_cardiac_valve_regurgitation | 1.49774132 |
27 | MP0005023_abnormal_wound_healing | 1.48342009 |
28 | MP0000733_abnormal_muscle_development | 1.47466611 |
29 | MP0000751_myopathy | 1.47252136 |
30 | MP0001879_abnormal_lymphatic_vessel | 1.46613803 |
31 | MP0003385_abnormal_body_wall | 1.46304887 |
32 | MP0005330_cardiomyopathy | 1.45615083 |
33 | MP0006138_congestive_heart_failure | 1.44789613 |
34 | MP0005076_abnormal_cell_differentiation | 1.43892977 |
35 | MP0002837_dystrophic_cardiac_calcinosis | 1.43713818 |
36 | MP0004185_abnormal_adipocyte_glucose | 1.43223220 |
37 | MP0009053_abnormal_anal_canal | 1.40702114 |
38 | MP0004087_abnormal_muscle_fiber | 1.39981389 |
39 | MP0000767_abnormal_smooth_muscle | 1.39907273 |
40 | MP0005409_darkened_coat_color | 1.37256328 |
41 | MP0002060_abnormal_skin_morphology | 1.36451763 |
42 | MP0000749_muscle_degeneration | 1.34231162 |
43 | MP0004782_abnormal_surfactant_physiolog | 1.33140053 |
44 | MP0005666_abnormal_adipose_tissue | 1.32140620 |
45 | MP0001299_abnormal_eye_distance/ | 1.31000806 |
46 | MP0009278_abnormal_bone_marrow | 1.25794679 |
47 | MP0002249_abnormal_larynx_morphology | 1.25491966 |
48 | MP0004036_abnormal_muscle_relaxation | 1.25105321 |
49 | MP0009250_abnormal_appendicular_skeleto | 1.24945973 |
50 | MP0002896_abnormal_bone_mineralization | 1.23493774 |
51 | MP0005385_cardiovascular_system_phenoty | 1.23458205 |
52 | MP0001544_abnormal_cardiovascular_syste | 1.23458205 |
53 | MP0002108_abnormal_muscle_morphology | 1.22921050 |
54 | MP0003950_abnormal_plasma_membrane | 1.21595146 |
55 | MP0003942_abnormal_urinary_system | 1.21198929 |
56 | MP0004233_abnormal_muscle_weight | 1.21021469 |
57 | MP0002877_abnormal_melanocyte_morpholog | 1.20920327 |
58 | MP0003091_abnormal_cell_migration | 1.18059261 |
59 | MP0005375_adipose_tissue_phenotype | 1.13641903 |
60 | MP0003984_embryonic_growth_retardation | 1.09626615 |
61 | MP0002088_abnormal_embryonic_growth/wei | 1.09059649 |
62 | MP0002972_abnormal_cardiac_muscle | 1.08512369 |
63 | MP0010386_abnormal_urinary_bladder | 1.07691979 |
64 | MP0004197_abnormal_fetal_growth/weight/ | 1.07062671 |
65 | MP0000428_abnormal_craniofacial_morphol | 1.06203792 |
66 | MP0002925_abnormal_cardiovascular_devel | 1.06038987 |
67 | MP0000003_abnormal_adipose_tissue | 1.05247191 |
68 | MP0005380_embryogenesis_phenotype | 1.04248095 |
69 | MP0001672_abnormal_embryogenesis/_devel | 1.04248095 |
70 | MP0002932_abnormal_joint_morphology | 1.03442931 |
71 | MP0005164_abnormal_response_to | 1.02994078 |
72 | MP0004130_abnormal_muscle_cell | 1.01852666 |
73 | MP0000266_abnormal_heart_morphology | 1.01848087 |
74 | MP0003115_abnormal_respiratory_system | 1.01735417 |
75 | MP0002128_abnormal_blood_circulation | 1.01495912 |
76 | MP0003935_abnormal_craniofacial_develop | 1.01042538 |
77 | MP0000759_abnormal_skeletal_muscle | 1.00998007 |
78 | MP0006054_spinal_hemorrhage | 1.00928683 |
79 | MP0000534_abnormal_ureter_morphology | 0.99416826 |
80 | MP0000537_abnormal_urethra_morphology | 0.98526455 |
81 | MP0005257_abnormal_intraocular_pressure | 0.97388097 |
82 | MP0004215_abnormal_myocardial_fiber | 0.97099173 |
83 | MP0002086_abnormal_extraembryonic_tissu | 0.96917936 |
84 | MP0003045_fibrosis | 0.95987456 |
85 | MP0002269_muscular_atrophy | 0.95873719 |
86 | MP0000516_abnormal_urinary_system | 0.95788719 |
87 | MP0005367_renal/urinary_system_phenotyp | 0.95788719 |
88 | MP0005197_abnormal_uvea_morphology | 0.95617344 |
89 | MP0001614_abnormal_blood_vessel | 0.95232664 |
90 | MP0005165_increased_susceptibility_to | 0.94346879 |
91 | MP0005620_abnormal_muscle_contractility | 0.94246744 |
92 | MP0005369_muscle_phenotype | 0.93780129 |
93 | MP0002106_abnormal_muscle_physiology | 0.93030556 |
94 | MP0000762_abnormal_tongue_morphology | 0.92992805 |
95 | MP0000049_abnormal_middle_ear | 0.92377724 |
96 | MP0002282_abnormal_trachea_morphology | 0.91737641 |
97 | MP0000432_abnormal_head_morphology | 0.89425091 |
98 | MP0002295_abnormal_pulmonary_circulatio | 0.89248894 |
99 | MP0002168_other_aberrant_phenotype | 0.89216404 |
100 | MP0002127_abnormal_cardiovascular_syste | 0.88941948 |
101 | MP0000538_abnormal_urinary_bladder | 0.88562935 |
102 | MP0002085_abnormal_embryonic_tissue | 0.87911998 |
103 | MP0000343_altered_response_to | 0.87766096 |
104 | MP0003755_abnormal_palate_morphology | 0.87763580 |
105 | MP0002234_abnormal_pharynx_morphology | 0.87606899 |
106 | MP0003937_abnormal_limbs/digits/tail_de | 0.86739237 |
107 | MP0002933_joint_inflammation | 0.85365914 |
108 | MP0002111_abnormal_tail_morphology | 0.84828112 |
109 | MP0005171_absent_coat_pigmentation | 0.84619162 |
110 | MP0005388_respiratory_system_phenotype | 0.83778442 |
111 | MP0002133_abnormal_respiratory_system | 0.83778442 |
112 | MP0002084_abnormal_developmental_patter | 0.82435086 |
113 | MP0000383_abnormal_hair_follicle | 0.81763575 |
114 | MP0004484_altered_response_of | 0.80996990 |
115 | MP0001293_anophthalmia | 0.79530520 |
116 | MP0001697_abnormal_embryo_size | 0.79479526 |
117 | MP0005083_abnormal_biliary_tract | 0.78858150 |
118 | MP0002115_abnormal_skeleton_extremities | 0.78263247 |
119 | MP0000163_abnormal_cartilage_morphology | 0.78088326 |
120 | MP0010678_abnormal_skin_adnexa | 0.77936141 |
121 | MP0003123_paternal_imprinting | 0.76602271 |
122 | MP0001915_intracranial_hemorrhage | 0.76460952 |
123 | MP0002138_abnormal_hepatobiliary_system | 0.75714515 |
124 | MP0001243_abnormal_dermal_layer | 0.75340339 |
125 | MP0003119_abnormal_digestive_system | 0.75246914 |
126 | MP0000569_abnormal_digit_pigmentation | 0.75059138 |
127 | MP0001175_abnormal_lung_morphology | 0.74599682 |
128 | MP0004957_abnormal_blastocyst_morpholog | 0.74343814 |
129 | MP0000249_abnormal_blood_vessel | 0.74044772 |
130 | MP0000427_abnormal_hair_cycle | 0.73573074 |
131 | MP0000230_abnormal_systemic_arterial | 0.73376744 |
132 | MP0005390_skeleton_phenotype | 0.73251476 |
133 | MP0000467_abnormal_esophagus_morphology | 0.71639660 |
134 | MP0003283_abnormal_digestive_organ | 0.70390518 |
135 | MP0000613_abnormal_salivary_gland | 0.67716331 |
136 | MP0002332_abnormal_exercise_endurance | 0.66991463 |
137 | MP0001661_extended_life_span | 0.65287328 |
138 | MP0002109_abnormal_limb_morphology | 0.64912673 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 5.62485824 |
2 | Premature rupture of membranes (HP:0001788) | 4.93044070 |
3 | Vascular tortuosity (HP:0004948) | 4.26664559 |
4 | Ankle contracture (HP:0006466) | 4.21866588 |
5 | Arterial tortuosity (HP:0005116) | 4.07645507 |
6 | Increased connective tissue (HP:0009025) | 3.91546340 |
7 | Shallow orbits (HP:0000586) | 3.73975127 |
8 | Broad metatarsal (HP:0001783) | 3.70747934 |
9 | Right ventricular cardiomyopathy (HP:0011663) | 3.38229463 |
10 | Cerebral aneurysm (HP:0004944) | 3.34262877 |
11 | Ventricular tachycardia (HP:0004756) | 3.32176433 |
12 | Aortic dissection (HP:0002647) | 3.27371709 |
13 | Type 1 muscle fiber predominance (HP:0003803) | 3.26340883 |
14 | Muscle fiber splitting (HP:0003555) | 3.01735747 |
15 | Aortic aneurysm (HP:0004942) | 3.01001426 |
16 | Spinal rigidity (HP:0003306) | 2.84612888 |
17 | Soft skin (HP:0000977) | 2.77419577 |
18 | Atrophic scars (HP:0001075) | 2.69060687 |
19 | Overgrowth (HP:0001548) | 2.66382466 |
20 | Lipoatrophy (HP:0100578) | 2.62945602 |
21 | Hyporeflexia of lower limbs (HP:0002600) | 2.58891273 |
22 | Short 4th metacarpal (HP:0010044) | 2.58855401 |
23 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.58855401 |
24 | Rectal prolapse (HP:0002035) | 2.58735988 |
25 | Sudden death (HP:0001699) | 2.58627962 |
26 | Spondylolisthesis (HP:0003302) | 2.55651124 |
27 | Aortic valve stenosis (HP:0001650) | 2.54003119 |
28 | Short nail (HP:0001799) | 2.51801692 |
29 | Exercise-induced muscle cramps (HP:0003710) | 2.50220955 |
30 | Cervical subluxation (HP:0003308) | 2.47789916 |
31 | Abnormality of the 4th metacarpal (HP:0010012) | 2.45971748 |
32 | Cardiovascular calcification (HP:0011915) | 2.44759266 |
33 | Blue sclerae (HP:0000592) | 2.44424103 |
34 | Aortic regurgitation (HP:0001659) | 2.36969953 |
35 | Selective tooth agenesis (HP:0001592) | 2.33293331 |
36 | Dilatation of the ascending aorta (HP:0005111) | 2.32984564 |
37 | Aneurysm (HP:0002617) | 2.32788873 |
38 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.31220597 |
39 | Bladder diverticulum (HP:0000015) | 2.29431803 |
40 | Wrist flexion contracture (HP:0001239) | 2.29346418 |
41 | Fragile skin (HP:0001030) | 2.24551878 |
42 | Increased variability in muscle fiber diameter (HP:0003557) | 2.22898122 |
43 | Mesangial abnormality (HP:0001966) | 2.21692962 |
44 | Difficulty climbing stairs (HP:0003551) | 2.18905318 |
45 | Broad toe (HP:0001837) | 2.16087334 |
46 | Broad face (HP:0000283) | 2.13414365 |
47 | Mitral valve prolapse (HP:0001634) | 2.12707062 |
48 | Follicular hyperkeratosis (HP:0007502) | 2.11876394 |
49 | Wide anterior fontanel (HP:0000260) | 2.11749145 |
50 | Tibial bowing (HP:0002982) | 2.09112503 |
51 | Mesomelia (HP:0003027) | 2.08404917 |
52 | Limited hip movement (HP:0008800) | 2.07005652 |
53 | Ulnar bowing (HP:0003031) | 2.06830180 |
54 | Peritonitis (HP:0002586) | 2.06577737 |
55 | Difficulty running (HP:0009046) | 2.06243869 |
56 | Lymphangioma (HP:0100764) | 2.05530932 |
57 | Abnormality of the calf musculature (HP:0001430) | 2.05307200 |
58 | Increased corneal curvature (HP:0100692) | 2.04857074 |
59 | Keratoconus (HP:0000563) | 2.04857074 |
60 | Wormian bones (HP:0002645) | 2.03941343 |
61 | Atrial fibrillation (HP:0005110) | 2.02748898 |
62 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.02732584 |
63 | Spinal cord lesions (HP:0100561) | 2.02390486 |
64 | Syringomyelia (HP:0003396) | 2.02390486 |
65 | Vertebral compression fractures (HP:0002953) | 1.99147709 |
66 | Hip contracture (HP:0003273) | 1.97048238 |
67 | Genu recurvatum (HP:0002816) | 1.96710306 |
68 | Interstitial pulmonary disease (HP:0006530) | 1.96204040 |
69 | Neonatal short-limb short stature (HP:0008921) | 1.95581761 |
70 | Vascular calcification (HP:0004934) | 1.95160276 |
71 | Abnormality of dentin (HP:0010299) | 1.95052668 |
72 | Broad hallux (HP:0010055) | 1.94572821 |
73 | Tubular atrophy (HP:0000092) | 1.93420821 |
74 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.93264127 |
75 | Subaortic stenosis (HP:0001682) | 1.93264127 |
76 | Joint stiffness (HP:0001387) | 1.92462156 |
77 | Distal lower limb muscle weakness (HP:0009053) | 1.91534953 |
78 | Bradycardia (HP:0001662) | 1.88890967 |
79 | Glucose intolerance (HP:0000833) | 1.88852943 |
80 | Coronal craniosynostosis (HP:0004440) | 1.87368416 |
81 | Scapular winging (HP:0003691) | 1.87259977 |
82 | Primary atrial arrhythmia (HP:0001692) | 1.86910038 |
83 | Elbow flexion contracture (HP:0002987) | 1.86487906 |
84 | Supraventricular arrhythmia (HP:0005115) | 1.86153798 |
85 | Osteolytic defects of the hand bones (HP:0009699) | 1.85988478 |
86 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.85988478 |
87 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.84404069 |
88 | Camptodactyly of toe (HP:0001836) | 1.83782547 |
89 | Radial bowing (HP:0002986) | 1.83703922 |
90 | Natal tooth (HP:0000695) | 1.82179928 |
91 | Abnormality of the nasal septum (HP:0000419) | 1.79676036 |
92 | Generalized amyotrophy (HP:0003700) | 1.78954620 |
93 | Morphological abnormality of the middle ear (HP:0008609) | 1.78806639 |
94 | Ovoid vertebral bodies (HP:0003300) | 1.78497804 |
95 | Mitral stenosis (HP:0001718) | 1.78314338 |
96 | Supraventricular tachycardia (HP:0004755) | 1.77901310 |
97 | Pulmonary artery stenosis (HP:0004415) | 1.77884320 |
98 | Bowed forearm bones (HP:0003956) | 1.77864349 |
99 | Bowing of the arm (HP:0006488) | 1.77864349 |
100 | Broad ribs (HP:0000885) | 1.76929597 |
101 | Hypoplastic ischia (HP:0003175) | 1.76906696 |
102 | Long toe (HP:0010511) | 1.76851898 |
103 | Striae distensae (HP:0001065) | 1.76316844 |
104 | Multiple enchondromatosis (HP:0005701) | 1.75798186 |
105 | Dilated cardiomyopathy (HP:0001644) | 1.75036756 |
106 | Calf muscle hypertrophy (HP:0008981) | 1.73945062 |
107 | Myoglobinuria (HP:0002913) | 1.73113841 |
108 | Abnormal hemoglobin (HP:0011902) | 1.72457068 |
109 | Abnormality of the calcaneus (HP:0008364) | 1.72234643 |
110 | Round ear (HP:0100830) | 1.71563568 |
111 | Tubulointerstitial fibrosis (HP:0005576) | 1.70704815 |
112 | Abnormality of the anterior chamber (HP:0000593) | 1.70311402 |
113 | Hyperextensible skin (HP:0000974) | 1.70237096 |
114 | Ectopia lentis (HP:0001083) | 1.69468706 |
115 | Preaxial foot polydactyly (HP:0001841) | 1.68785529 |
116 | Knee flexion contracture (HP:0006380) | 1.68697195 |
117 | Abnormality of the right ventricle (HP:0001707) | 1.68677198 |
118 | Renal duplication (HP:0000075) | 1.68100907 |
119 | Hypoplasia of the iris (HP:0007676) | 1.67967322 |
120 | Slender build (HP:0001533) | 1.67839192 |
121 | Abnormality of the acetabulum (HP:0003170) | 1.67806514 |
122 | Hematochezia (HP:0002573) | 1.67655679 |
123 | Biconcave vertebral bodies (HP:0004586) | 1.67314857 |
124 | Mitral regurgitation (HP:0001653) | 1.66924776 |
125 | Joint laxity (HP:0001388) | 1.66505232 |
126 | Protruding ear (HP:0000411) | 1.66406348 |
127 | Fused cervical vertebrae (HP:0002949) | 1.66006018 |
128 | Milia (HP:0001056) | 1.65884007 |
129 | Acanthosis nigricans (HP:0000956) | 1.62890651 |
130 | Adactyly (HP:0009776) | 1.62839868 |
131 | Short hallux (HP:0010109) | 1.62600634 |
132 | Asymmetric septal hypertrophy (HP:0001670) | 1.62592858 |
133 | Bulbous nose (HP:0000414) | 1.61361353 |
134 | Hydroureter (HP:0000072) | 1.60623278 |
135 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.60227856 |
136 | EMG: myopathic abnormalities (HP:0003458) | 1.59960075 |
137 | Tarsal synostosis (HP:0008368) | 1.59864020 |
138 | Anterior segment dysgenesis (HP:0007700) | 1.59862802 |
139 | Coxa vara (HP:0002812) | 1.59686323 |
140 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.59380791 |
141 | Deviation of the hallux (HP:0010051) | 1.58737568 |
142 | Bowel diverticulosis (HP:0005222) | 1.58317151 |
143 | Broad thumb (HP:0011304) | 1.57955872 |
144 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.56784471 |
145 | Short humerus (HP:0005792) | 1.56576081 |
146 | Entropion (HP:0000621) | 1.56018377 |
147 | Short 5th finger (HP:0009237) | 1.54295450 |
148 | Disproportionate tall stature (HP:0001519) | 1.53868922 |
149 | Chorioretinal atrophy (HP:0000533) | 1.53313915 |
150 | Infantile muscular hypotonia (HP:0008947) | 1.52690397 |
151 | Buphthalmos (HP:0000557) | 1.50133266 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 3.71210022 |
2 | TRIB3 | 3.70742636 |
3 | FRK | 2.80177744 |
4 | LATS1 | 2.73228647 |
5 | DDR2 | 2.73047860 |
6 | PDGFRA | 2.53828821 |
7 | CDK12 | 2.43010669 |
8 | PKN2 | 2.34872428 |
9 | ERN1 | 2.26384431 |
10 | EPHB2 | 2.03802961 |
11 | SIK1 | 1.91976139 |
12 | MYLK | 1.85588043 |
13 | LATS2 | 1.80035445 |
14 | TGFBR2 | 1.75943384 |
15 | MAP3K10 | 1.72979116 |
16 | TIE1 | 1.71807007 |
17 | DMPK | 1.62485986 |
18 | STK38L | 1.62466704 |
19 | NTRK1 | 1.52304771 |
20 | STK38 | 1.52088487 |
21 | EPHA2 | 1.50493703 |
22 | STK3 | 1.49808066 |
23 | RIPK1 | 1.46360265 |
24 | BMX | 1.43409429 |
25 | ADRBK1 | 1.43185188 |
26 | ERBB4 | 1.39948021 |
27 | EPHB1 | 1.34611648 |
28 | PAK2 | 1.32583186 |
29 | ICK | 1.32348034 |
30 | LRRK2 | 1.30658662 |
31 | CDK7 | 1.29126671 |
32 | BMPR1B | 1.28011343 |
33 | MET | 1.27479796 |
34 | STK10 | 1.24687201 |
35 | OBSCN | 1.24296037 |
36 | WNK4 | 1.23832776 |
37 | LIMK1 | 1.21574537 |
38 | EEF2K | 1.21322537 |
39 | PIK3CA | 1.20689711 |
40 | TRPM7 | 1.20463815 |
41 | CAMK1D | 1.14457634 |
42 | MTOR | 1.14366892 |
43 | KDR | 1.10137355 |
44 | FLT3 | 1.08834864 |
45 | PAK4 | 1.07964477 |
46 | ILK | 1.04522519 |
47 | RPS6KA4 | 1.03983916 |
48 | FER | 1.03035025 |
49 | PTK6 | 1.02924743 |
50 | NEK1 | 1.00799733 |
51 | PTK2 | 1.00336872 |
52 | MAPK15 | 0.99664566 |
53 | RPS6KA2 | 0.99615186 |
54 | RPS6KB2 | 0.97746239 |
55 | MAP3K7 | 0.96181275 |
56 | ADRBK2 | 0.95964741 |
57 | GRK7 | 0.95770678 |
58 | BCKDK | 0.95661113 |
59 | MAP2K3 | 0.94512421 |
60 | MAPKAPK3 | 0.93149550 |
61 | TTK | 0.92420243 |
62 | GRK1 | 0.92248441 |
63 | TGFBR1 | 0.91712765 |
64 | STK39 | 0.91595694 |
65 | ZAK | 0.91332066 |
66 | NME2 | 0.90871984 |
67 | PDK3 | 0.90774989 |
68 | PDK4 | 0.90774989 |
69 | LMTK2 | 0.89940929 |
70 | CDK6 | 0.89846088 |
71 | NEK9 | 0.88728810 |
72 | MELK | 0.88029068 |
73 | PRKD2 | 0.83587880 |
74 | PIK3CG | 0.83435378 |
75 | STK24 | 0.83377179 |
76 | CDK4 | 0.82527820 |
77 | FGFR1 | 0.81007988 |
78 | INSRR | 0.80445708 |
79 | STK4 | 0.80101037 |
80 | MOS | 0.78709502 |
81 | EPHA3 | 0.77775221 |
82 | MAP3K3 | 0.77653515 |
83 | PRKCE | 0.76726377 |
84 | NEK2 | 0.76592924 |
85 | CHUK | 0.73804968 |
86 | MAP3K8 | 0.72730607 |
87 | PDGFRB | 0.70530778 |
88 | CDC42BPA | 0.69195970 |
89 | ABL2 | 0.67826098 |
90 | PRKD1 | 0.63508681 |
91 | MAP2K1 | 0.61458506 |
92 | PIM2 | 0.61191053 |
93 | MAPK7 | 0.59561618 |
94 | ROCK1 | 0.59350423 |
95 | PDK2 | 0.57197067 |
96 | MAP3K6 | 0.57016852 |
97 | PIM1 | 0.56839130 |
98 | CDK8 | 0.55604247 |
99 | AURKB | 0.53124206 |
100 | PRKAA2 | 0.52041540 |
101 | RPS6KL1 | 0.51439199 |
102 | RPS6KC1 | 0.51439199 |
103 | NUAK1 | 0.51313692 |
104 | MST1R | 0.51281540 |
105 | SGK3 | 0.51040603 |
106 | ACVR1B | 0.50032582 |
107 | AKT3 | 0.49859177 |
108 | FGFR3 | 0.49297066 |
109 | PNCK | 0.49131895 |
110 | PLK1 | 0.48723193 |
111 | AKT2 | 0.48346210 |
112 | PAK3 | 0.48342336 |
113 | ROCK2 | 0.47547634 |
114 | TAOK2 | 0.47337085 |
115 | MAPKAPK2 | 0.47179660 |
116 | TYRO3 | 0.47046503 |
117 | RPS6KA6 | 0.45822553 |
118 | CSK | 0.45133153 |
119 | PHKG1 | 0.45105503 |
120 | PHKG2 | 0.45105503 |
121 | BRD4 | 0.44462655 |
122 | WEE1 | 0.43107490 |
123 | DYRK1B | 0.41919206 |
124 | PAK1 | 0.41555398 |
125 | BRSK2 | 0.41467094 |
126 | WNK1 | 0.39256869 |
127 | PRKG2 | 0.38803500 |
128 | MUSK | 0.38357658 |
129 | FGFR2 | 0.37833322 |
130 | GSK3A | 0.37774088 |
131 | PTK2B | 0.37426011 |
132 | CAMK1G | 0.37361839 |
133 | ZAP70 | 0.36344272 |
134 | MARK2 | 0.33106225 |
135 | PRKAA1 | 0.32186306 |
136 | IGF1R | 0.30741153 |
137 | MAPKAPK5 | 0.28534189 |
138 | ABL1 | 0.28525335 |
139 | INSR | 0.27869806 |
140 | CAMK1 | 0.26877925 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.81773754 |
2 | Adherens junction_Homo sapiens_hsa04520 | 2.38834581 |
3 | Focal adhesion_Homo sapiens_hsa04510 | 2.33313201 |
4 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.30204770 |
5 | Small cell lung cancer_Homo sapiens_hsa05222 | 2.16709674 |
6 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.11869259 |
7 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.08717059 |
8 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.07435135 |
9 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.00933189 |
10 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.97732332 |
11 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.90865856 |
12 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.89691102 |
13 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.84371111 |
14 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.84029768 |
15 | Viral myocarditis_Homo sapiens_hsa05416 | 1.81236803 |
16 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.69769106 |
17 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.66779699 |
18 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.64978831 |
19 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.58058082 |
20 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.57245738 |
21 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.55561873 |
22 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.53280597 |
23 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.51701678 |
24 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.49851871 |
25 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.45612208 |
26 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.43301875 |
27 | Bladder cancer_Homo sapiens_hsa05219 | 1.38518709 |
28 | Axon guidance_Homo sapiens_hsa04360 | 1.35201524 |
29 | Amoebiasis_Homo sapiens_hsa05146 | 1.33310772 |
30 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.32045084 |
31 | Tight junction_Homo sapiens_hsa04530 | 1.31214891 |
32 | Cell cycle_Homo sapiens_hsa04110 | 1.28616428 |
33 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.25346821 |
34 | Lysine degradation_Homo sapiens_hsa00310 | 1.21815795 |
35 | Base excision repair_Homo sapiens_hsa03410 | 1.20225732 |
36 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.18343990 |
37 | Pathways in cancer_Homo sapiens_hsa05200 | 1.17834067 |
38 | Circadian rhythm_Homo sapiens_hsa04710 | 1.17784904 |
39 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.17123929 |
40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.15440431 |
41 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.12418569 |
42 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.12380600 |
43 | HTLV-I infection_Homo sapiens_hsa05166 | 1.09578125 |
44 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.08650027 |
45 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.08293521 |
46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.04917614 |
47 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.03931905 |
48 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.03625264 |
49 | RNA transport_Homo sapiens_hsa03013 | 1.03440507 |
50 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.03074784 |
51 | Prostate cancer_Homo sapiens_hsa05215 | 1.02755351 |
52 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.02333394 |
53 | Mismatch repair_Homo sapiens_hsa03430 | 1.00603958 |
54 | Melanoma_Homo sapiens_hsa05218 | 0.99623180 |
55 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.99506362 |
56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.98800694 |
57 | Insulin resistance_Homo sapiens_hsa04931 | 0.98165336 |
58 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.94752298 |
59 | Thyroid cancer_Homo sapiens_hsa05216 | 0.93522600 |
60 | Ribosome_Homo sapiens_hsa03010 | 0.93215768 |
61 | DNA replication_Homo sapiens_hsa03030 | 0.92302062 |
62 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.91869487 |
63 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.90101747 |
64 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.89958864 |
65 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.89917518 |
66 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.89042508 |
67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.89041136 |
68 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.88678599 |
69 | Carbon metabolism_Homo sapiens_hsa01200 | 0.88129967 |
70 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.87959412 |
71 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.87066278 |
72 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.86380046 |
73 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.86186402 |
74 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.84286445 |
75 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.84045734 |
76 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.83630441 |
77 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.83007729 |
78 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.79979743 |
79 | Melanogenesis_Homo sapiens_hsa04916 | 0.79711032 |
80 | Phototransduction_Homo sapiens_hsa04744 | 0.79146820 |
81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.77460146 |
82 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77287690 |
83 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.76758527 |
84 | Spliceosome_Homo sapiens_hsa03040 | 0.76453164 |
85 | Shigellosis_Homo sapiens_hsa05131 | 0.76347474 |
86 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75965321 |
87 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.75458553 |
88 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.74155186 |
89 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.72890837 |
90 | Malaria_Homo sapiens_hsa05144 | 0.71765417 |
91 | Renin secretion_Homo sapiens_hsa04924 | 0.71668852 |
92 | ABC transporters_Homo sapiens_hsa02010 | 0.71034291 |
93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.70193981 |
94 | Endometrial cancer_Homo sapiens_hsa05213 | 0.69061339 |
95 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.68438700 |
96 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.68160123 |
97 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.67471451 |
98 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.66982737 |
99 | Apoptosis_Homo sapiens_hsa04210 | 0.66711713 |
100 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.66558927 |
101 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.66488807 |
102 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66328050 |
103 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.64962892 |
104 | Histidine metabolism_Homo sapiens_hsa00340 | 0.64463505 |
105 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.63422240 |
106 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.63300603 |
107 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.63258548 |
108 | Homologous recombination_Homo sapiens_hsa03440 | 0.62143148 |
109 | Salivary secretion_Homo sapiens_hsa04970 | 0.61718812 |
110 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.60027390 |
111 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.59783126 |
112 | Endocytosis_Homo sapiens_hsa04144 | 0.58314655 |
113 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.57162707 |
114 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.55988875 |
115 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.55820804 |
116 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55525570 |
117 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.55450900 |
118 | Platelet activation_Homo sapiens_hsa04611 | 0.55299296 |
119 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.54771477 |
120 | Gap junction_Homo sapiens_hsa04540 | 0.54688425 |
121 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.54579953 |
122 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.53825513 |
123 | Legionellosis_Homo sapiens_hsa05134 | 0.53560373 |
124 | Colorectal cancer_Homo sapiens_hsa05210 | 0.52768084 |
125 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.52067530 |
126 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.51647865 |
127 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51629285 |
128 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.51478243 |
129 | Hepatitis B_Homo sapiens_hsa05161 | 0.51332267 |
130 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.49143821 |
131 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.47595411 |
132 | Lysosome_Homo sapiens_hsa04142 | 0.47520053 |
133 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.47238240 |
134 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.46507698 |
135 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.46339480 |
136 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.45998180 |
137 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.45701250 |
138 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.45298768 |
139 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45278942 |
140 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.45225355 |
141 | Mineral absorption_Homo sapiens_hsa04978 | 0.45123781 |
142 | Bile secretion_Homo sapiens_hsa04976 | 0.44260764 |
143 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.44188827 |
144 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.44156813 |
145 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.43657089 |
146 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.42836882 |
147 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.42596602 |
148 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.40817719 |
149 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.40357115 |
150 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.39958213 |
151 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.39364518 |
152 | Galactose metabolism_Homo sapiens_hsa00052 | 0.39247221 |
153 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.36593360 |
154 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.35049477 |