

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | signal peptide processing (GO:0006465) | 5.86801540 |
| 2 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.86478446 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.75015912 |
| 4 | viral transcription (GO:0019083) | 5.71285502 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.38596473 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 5.38596473 |
| 7 | cell wall macromolecule metabolic process (GO:0044036) | 5.35038790 |
| 8 | translational termination (GO:0006415) | 5.33332929 |
| 9 | respiratory electron transport chain (GO:0022904) | 5.24855283 |
| 10 | electron transport chain (GO:0022900) | 5.13339215 |
| 11 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.09778290 |
| 12 | cotranslational protein targeting to membrane (GO:0006613) | 4.97078623 |
| 13 | protein targeting to ER (GO:0045047) | 4.91783252 |
| 14 | protein localization to endoplasmic reticulum (GO:0070972) | 4.74575118 |
| 15 | ribosomal large subunit biogenesis (GO:0042273) | 4.73038838 |
| 16 | ribosomal small subunit assembly (GO:0000028) | 4.70403914 |
| 17 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.63382941 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.46445588 |
| 19 | translational elongation (GO:0006414) | 4.41172409 |
| 20 | cellular response to leptin stimulus (GO:0044320) | 4.39325369 |
| 21 | aldehyde catabolic process (GO:0046185) | 4.36528513 |
| 22 | cell wall macromolecule catabolic process (GO:0016998) | 4.16310995 |
| 23 | translational initiation (GO:0006413) | 4.10196034 |
| 24 | viral life cycle (GO:0019058) | 4.08085874 |
| 25 | chaperone-mediated protein transport (GO:0072321) | 4.06739785 |
| 26 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.05700341 |
| 27 | cellular protein complex disassembly (GO:0043624) | 4.01848290 |
| 28 | hydrogen ion transmembrane transport (GO:1902600) | 3.77531530 |
| 29 | DNA damage response, detection of DNA damage (GO:0042769) | 3.77113565 |
| 30 | response to leptin (GO:0044321) | 3.75606777 |
| 31 | cullin deneddylation (GO:0010388) | 3.75447085 |
| 32 | axonemal dynein complex assembly (GO:0070286) | 3.72528303 |
| 33 | protein neddylation (GO:0045116) | 3.66004696 |
| 34 | regulation of oxidative phosphorylation (GO:0002082) | 3.62285839 |
| 35 | proton transport (GO:0015992) | 3.61554427 |
| 36 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 3.57191786 |
| 37 | hydrogen transport (GO:0006818) | 3.54091624 |
| 38 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.50854910 |
| 39 | termination of RNA polymerase III transcription (GO:0006386) | 3.50854910 |
| 40 | proteasome assembly (GO:0043248) | 3.45845249 |
| 41 | inner mitochondrial membrane organization (GO:0007007) | 3.44372127 |
| 42 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.40086517 |
| 43 | nonmotile primary cilium assembly (GO:0035058) | 3.38706879 |
| 44 | striatum development (GO:0021756) | 3.34878921 |
| 45 | dendritic spine morphogenesis (GO:0060997) | 3.34652814 |
| 46 | regulation of cilium movement (GO:0003352) | 3.31253460 |
| 47 | protein complex disassembly (GO:0043241) | 3.28830475 |
| 48 | DNA deamination (GO:0045006) | 3.26960231 |
| 49 | translation (GO:0006412) | 3.25621341 |
| 50 | protein localization to mitochondrion (GO:0070585) | 3.25219512 |
| 51 | regulation of pigment cell differentiation (GO:0050932) | 3.20860855 |
| 52 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.19770572 |
| 53 | macromolecular complex disassembly (GO:0032984) | 3.15847419 |
| 54 | protein-cofactor linkage (GO:0018065) | 3.14940287 |
| 55 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.14521042 |
| 56 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.13205995 |
| 57 | viral protein processing (GO:0019082) | 3.11340940 |
| 58 | negative regulation of response to food (GO:0032096) | 3.10375457 |
| 59 | negative regulation of appetite (GO:0032099) | 3.10375457 |
| 60 | inner ear receptor cell development (GO:0060119) | 3.08884954 |
| 61 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.08867138 |
| 62 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.08867138 |
| 63 | protein targeting to membrane (GO:0006612) | 3.07405744 |
| 64 | protein deneddylation (GO:0000338) | 3.05929180 |
| 65 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.01038122 |
| 66 | negative regulation of macrophage differentiation (GO:0045650) | 3.00564095 |
| 67 | ATP biosynthetic process (GO:0006754) | 2.94983626 |
| 68 | negative regulation of heart rate (GO:0010459) | 2.91637792 |
| 69 | cilium movement (GO:0003341) | 2.90455256 |
| 70 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 2.89192889 |
| 71 | maturation of SSU-rRNA (GO:0030490) | 2.87111051 |
| 72 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.86112299 |
| 73 | NADH dehydrogenase complex assembly (GO:0010257) | 2.86112299 |
| 74 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.86112299 |
| 75 | protein targeting to mitochondrion (GO:0006626) | 2.85007036 |
| 76 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.83890949 |
| 77 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.82298083 |
| 78 | mRNA catabolic process (GO:0006402) | 2.82008743 |
| 79 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.81864785 |
| 80 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.80881676 |
| 81 | establishment of protein localization to mitochondrion (GO:0072655) | 2.80813221 |
| 82 | protein complex biogenesis (GO:0070271) | 2.80003933 |
| 83 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.79916030 |
| 84 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 2.79804217 |
| 85 | centriole replication (GO:0007099) | 2.79065376 |
| 86 | cellular respiration (GO:0045333) | 2.78707700 |
| 87 | positive regulation of developmental pigmentation (GO:0048087) | 2.77066042 |
| 88 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.76678551 |
| 89 | regulation of immunoglobulin secretion (GO:0051023) | 2.75489988 |
| 90 | tyrosine metabolic process (GO:0006570) | 2.75215686 |
| 91 | pre-miRNA processing (GO:0031054) | 2.70325600 |
| 92 | single strand break repair (GO:0000012) | 2.68932562 |
| 93 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 2.68893597 |
| 94 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 2.63367378 |
| 95 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.60638109 |
| 96 | artery smooth muscle contraction (GO:0014824) | 2.58280521 |
| 97 | RNA catabolic process (GO:0006401) | 2.57577359 |
| 98 | regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803) | 2.56710016 |
| 99 | regulation of appetite (GO:0032098) | 2.56377848 |
| 100 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.54429420 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.08711803 |
| 2 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.99628703 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.58033822 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.55826499 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.46121886 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.43671985 |
| 7 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.37983126 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.37414426 |
| 9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.94374314 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.58537677 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.52086664 |
| 12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.31561470 |
| 13 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.29575435 |
| 14 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.23081752 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.16995369 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.08484887 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.04700504 |
| 18 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.00999312 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.92283150 |
| 20 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.83270884 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.82760510 |
| 22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.78238675 |
| 23 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.70285215 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.67515144 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.66055699 |
| 26 | P300_19829295_ChIP-Seq_ESCs_Human | 1.65876782 |
| 27 | VDR_22108803_ChIP-Seq_LS180_Human | 1.63465261 |
| 28 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.61796061 |
| 29 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.60796443 |
| 30 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.59819340 |
| 31 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.59465872 |
| 32 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.57654196 |
| 33 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.56029224 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.53992130 |
| 35 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.52215148 |
| 36 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.51854861 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.51310243 |
| 38 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.47503792 |
| 39 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.46907466 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40201875 |
| 41 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.39692244 |
| 42 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.37648523 |
| 43 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.36423426 |
| 44 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.33755626 |
| 45 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.33170563 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.30571680 |
| 47 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.30081806 |
| 48 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.30081806 |
| 49 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.28879111 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.28864360 |
| 51 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.28217364 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.25407631 |
| 53 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.24579939 |
| 54 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.24412070 |
| 55 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.23519570 |
| 56 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.23090829 |
| 57 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.22201144 |
| 58 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.22177743 |
| 59 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.22177743 |
| 60 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.21885069 |
| 61 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.20347727 |
| 62 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.19015684 |
| 63 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.15452354 |
| 64 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.13295937 |
| 65 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.11701187 |
| 66 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.11587758 |
| 67 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10470228 |
| 68 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.10452602 |
| 69 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05769899 |
| 70 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.05579868 |
| 71 | JUN_21703547_ChIP-Seq_K562_Human | 1.04823455 |
| 72 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.04039793 |
| 73 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.03365335 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.03242663 |
| 75 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.02995123 |
| 76 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02802488 |
| 77 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.02796588 |
| 78 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.02636402 |
| 79 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.02502827 |
| 80 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02210818 |
| 81 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.01977042 |
| 82 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.01807893 |
| 83 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.01472807 |
| 84 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.00693739 |
| 85 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.00434086 |
| 86 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.99475440 |
| 87 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.99444097 |
| 88 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.99308924 |
| 89 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.97476247 |
| 90 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.97375433 |
| 91 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.97326331 |
| 92 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.97263345 |
| 93 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.97091307 |
| 94 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.96241507 |
| 95 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96240032 |
| 96 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.96010176 |
| 97 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95489177 |
| 98 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.95344582 |
| 99 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.95300162 |
| 100 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95295109 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 6.35574760 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.96766849 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.38605133 |
| 4 | MP0005360_urolithiasis | 3.26720323 |
| 5 | MP0001529_abnormal_vocalization | 2.95052893 |
| 6 | MP0008789_abnormal_olfactory_epithelium | 2.91187818 |
| 7 | MP0003646_muscle_fatigue | 2.63240364 |
| 8 | MP0005499_abnormal_olfactory_system | 2.61675462 |
| 9 | MP0005394_taste/olfaction_phenotype | 2.61675462 |
| 10 | MP0005075_abnormal_melanosome_morpholog | 2.53088049 |
| 11 | MP0005646_abnormal_pituitary_gland | 2.41939927 |
| 12 | MP0004858_abnormal_nervous_system | 2.30191308 |
| 13 | MP0002837_dystrophic_cardiac_calcinosis | 2.24197160 |
| 14 | MP0009697_abnormal_copulation | 2.22611327 |
| 15 | MP0001984_abnormal_olfaction | 2.19174500 |
| 16 | MP0001188_hyperpigmentation | 2.18195907 |
| 17 | MP0004381_abnormal_hair_follicle | 2.03750433 |
| 18 | MP0008877_abnormal_DNA_methylation | 2.00210876 |
| 19 | MP0002277_abnormal_respiratory_mucosa | 1.93325212 |
| 20 | MP0003806_abnormal_nucleotide_metabolis | 1.89310401 |
| 21 | MP0002938_white_spotting | 1.76011032 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 1.68301565 |
| 23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.60150555 |
| 24 | MP0002102_abnormal_ear_morphology | 1.59163606 |
| 25 | MP0002163_abnormal_gland_morphology | 1.56536038 |
| 26 | MP0000750_abnormal_muscle_regeneration | 1.54483924 |
| 27 | MP0003186_abnormal_redox_activity | 1.52045408 |
| 28 | MP0000372_irregular_coat_pigmentation | 1.50656765 |
| 29 | MP0002095_abnormal_skin_pigmentation | 1.50599053 |
| 30 | MP0001835_abnormal_antigen_presentation | 1.50573602 |
| 31 | MP0003121_genomic_imprinting | 1.48635714 |
| 32 | MP0002822_catalepsy | 1.42650562 |
| 33 | MP0003122_maternal_imprinting | 1.38875766 |
| 34 | MP0005171_absent_coat_pigmentation | 1.36884897 |
| 35 | MP0008872_abnormal_physiological_respon | 1.35171516 |
| 36 | MP0003787_abnormal_imprinting | 1.33141649 |
| 37 | MP0001440_abnormal_grooming_behavior | 1.29306374 |
| 38 | MP0002272_abnormal_nervous_system | 1.29017726 |
| 39 | MP0003011_delayed_dark_adaptation | 1.28985007 |
| 40 | MP0001968_abnormal_touch/_nociception | 1.28203851 |
| 41 | MP0005645_abnormal_hypothalamus_physiol | 1.23308128 |
| 42 | MP0005379_endocrine/exocrine_gland_phen | 1.22922860 |
| 43 | MP0004147_increased_porphyrin_level | 1.21304889 |
| 44 | MP0002736_abnormal_nociception_after | 1.20382858 |
| 45 | MP0005551_abnormal_eye_electrophysiolog | 1.19351765 |
| 46 | MP0003195_calcinosis | 1.15270316 |
| 47 | MP0004859_abnormal_synaptic_plasticity | 1.14697544 |
| 48 | MP0001905_abnormal_dopamine_level | 1.13960367 |
| 49 | MP0009785_altered_susceptibility_to | 1.13173390 |
| 50 | MP0004142_abnormal_muscle_tone | 1.07435639 |
| 51 | MP0002557_abnormal_social/conspecific_i | 1.03874395 |
| 52 | MP0001790_abnormal_immune_system | 1.02260135 |
| 53 | MP0005387_immune_system_phenotype | 1.02260135 |
| 54 | MP0005253_abnormal_eye_physiology | 1.01662481 |
| 55 | MP0004145_abnormal_muscle_electrophysio | 0.99877220 |
| 56 | MP0009046_muscle_twitch | 0.99119060 |
| 57 | MP0000778_abnormal_nervous_system | 0.97717168 |
| 58 | MP0009764_decreased_sensitivity_to | 0.97524699 |
| 59 | MP0009745_abnormal_behavioral_response | 0.96679718 |
| 60 | MP0001485_abnormal_pinna_reflex | 0.95555837 |
| 61 | MP0003718_maternal_effect | 0.94049595 |
| 62 | MP0002572_abnormal_emotion/affect_behav | 0.93853563 |
| 63 | MP0005332_abnormal_amino_acid | 0.92746450 |
| 64 | MP0005671_abnormal_response_to | 0.92587354 |
| 65 | MP0006276_abnormal_autonomic_nervous | 0.92392409 |
| 66 | MP0006036_abnormal_mitochondrial_physio | 0.92092180 |
| 67 | MP0002751_abnormal_autonomic_nervous | 0.90607969 |
| 68 | MP0002090_abnormal_vision | 0.90306111 |
| 69 | MP0002933_joint_inflammation | 0.88588224 |
| 70 | MP0002733_abnormal_thermal_nociception | 0.88208336 |
| 71 | MP0005636_abnormal_mineral_homeostasis | 0.87824943 |
| 72 | MP0003123_paternal_imprinting | 0.87774488 |
| 73 | MP0003866_abnormal_defecation | 0.86752186 |
| 74 | MP0001970_abnormal_pain_threshold | 0.86472671 |
| 75 | MP0005266_abnormal_metabolism | 0.81345552 |
| 76 | MP0002184_abnormal_innervation | 0.81326179 |
| 77 | MP0002752_abnormal_somatic_nervous | 0.80303803 |
| 78 | MP0005195_abnormal_posterior_eye | 0.77249065 |
| 79 | MP0000230_abnormal_systemic_arterial | 0.76981605 |
| 80 | MP0000685_abnormal_immune_system | 0.76171624 |
| 81 | MP0005386_behavior/neurological_phenoty | 0.74948657 |
| 82 | MP0004924_abnormal_behavior | 0.74948657 |
| 83 | MP0001663_abnormal_digestive_system | 0.74107856 |
| 84 | MP0005389_reproductive_system_phenotype | 0.73979254 |
| 85 | MP0001764_abnormal_homeostasis | 0.73367975 |
| 86 | MP0005503_abnormal_tendon_morphology | 0.73350380 |
| 87 | MP0002653_abnormal_ependyma_morphology | 0.72477490 |
| 88 | MP0001286_abnormal_eye_development | 0.72220610 |
| 89 | MP0008058_abnormal_DNA_repair | 0.71223186 |
| 90 | MP0008873_increased_physiological_sensi | 0.71197630 |
| 91 | MP0001486_abnormal_startle_reflex | 0.70973056 |
| 92 | MP0001765_abnormal_ion_homeostasis | 0.70879930 |
| 93 | MP0001756_abnormal_urination | 0.70275215 |
| 94 | MP0002332_abnormal_exercise_endurance | 0.69069598 |
| 95 | MP0000920_abnormal_myelination | 0.66913145 |
| 96 | MP0001919_abnormal_reproductive_system | 0.66010943 |
| 97 | MP0002063_abnormal_learning/memory/cond | 0.65877446 |
| 98 | MP0003635_abnormal_synaptic_transmissio | 0.65767930 |
| 99 | MP0005423_abnormal_somatic_nervous | 0.65390290 |
| 100 | MP0010386_abnormal_urinary_bladder | 0.63269741 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.46525919 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.66782432 |
| 3 | Hypoglycemic seizures (HP:0002173) | 4.66496618 |
| 4 | Progressive macrocephaly (HP:0004481) | 4.58538101 |
| 5 | Mitochondrial inheritance (HP:0001427) | 4.37916063 |
| 6 | Congenital, generalized hypertrichosis (HP:0004540) | 4.32446870 |
| 7 | Acute encephalopathy (HP:0006846) | 4.26667156 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 4.13139068 |
| 9 | Hypothermia (HP:0002045) | 4.06789439 |
| 10 | Reticulocytopenia (HP:0001896) | 4.04692631 |
| 11 | Increased CSF lactate (HP:0002490) | 3.97838637 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.93216443 |
| 13 | Rectal fistula (HP:0100590) | 3.86779727 |
| 14 | Rectovaginal fistula (HP:0000143) | 3.86779727 |
| 15 | Hepatic necrosis (HP:0002605) | 3.73271905 |
| 16 | Cerebral edema (HP:0002181) | 3.69301994 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.60088515 |
| 18 | Abnormal ciliary motility (HP:0012262) | 3.43475820 |
| 19 | Myokymia (HP:0002411) | 3.34831981 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 3.30908214 |
| 21 | Macrocytic anemia (HP:0001972) | 3.30619223 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 3.27661623 |
| 23 | Hypoglycemic coma (HP:0001325) | 3.24733247 |
| 24 | Intestinal fistula (HP:0100819) | 3.11211318 |
| 25 | Symptomatic seizures (HP:0011145) | 3.07472565 |
| 26 | Vaginal fistula (HP:0004320) | 3.07348470 |
| 27 | Median cleft lip (HP:0000161) | 3.00036938 |
| 28 | Stomatitis (HP:0010280) | 2.99221793 |
| 29 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.98398801 |
| 30 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.88782420 |
| 31 | Exertional dyspnea (HP:0002875) | 2.88335350 |
| 32 | Methylmalonic acidemia (HP:0002912) | 2.85515554 |
| 33 | Leukodystrophy (HP:0002415) | 2.85186724 |
| 34 | Medial flaring of the eyebrow (HP:0010747) | 2.82999861 |
| 35 | Dyschromatopsia (HP:0007641) | 2.82311296 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.77421165 |
| 37 | Optic disc pallor (HP:0000543) | 2.74130118 |
| 38 | Cheilitis (HP:0100825) | 2.72206506 |
| 39 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.66700873 |
| 40 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.57786964 |
| 41 | Abnormal number of erythroid precursors (HP:0012131) | 2.52874450 |
| 42 | Molar tooth sign on MRI (HP:0002419) | 2.50443191 |
| 43 | Abnormality of midbrain morphology (HP:0002418) | 2.50443191 |
| 44 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.50055156 |
| 45 | Decreased central vision (HP:0007663) | 2.49653079 |
| 46 | Woolly hair (HP:0002224) | 2.46846465 |
| 47 | Pallor (HP:0000980) | 2.44497242 |
| 48 | Abnormality of renal resorption (HP:0011038) | 2.36756056 |
| 49 | Glycosuria (HP:0003076) | 2.35555890 |
| 50 | Abnormality of urine glucose concentration (HP:0011016) | 2.35555890 |
| 51 | Renal cortical cysts (HP:0000803) | 2.31635526 |
| 52 | Duplicated collecting system (HP:0000081) | 2.30324404 |
| 53 | Gait imbalance (HP:0002141) | 2.29220394 |
| 54 | Increased intramyocellular lipid droplets (HP:0012240) | 2.28563511 |
| 55 | Abnormal hemoglobin (HP:0011902) | 2.28421356 |
| 56 | Respiratory failure (HP:0002878) | 2.24530368 |
| 57 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.24384846 |
| 58 | Abnormality of the renal collecting system (HP:0004742) | 2.22439527 |
| 59 | Nephrogenic diabetes insipidus (HP:0009806) | 2.19802440 |
| 60 | Methylmalonic aciduria (HP:0012120) | 2.17908904 |
| 61 | Neutropenia (HP:0001875) | 2.17047655 |
| 62 | Respiratory difficulties (HP:0002880) | 2.14664130 |
| 63 | Congenital primary aphakia (HP:0007707) | 2.13551263 |
| 64 | Hypoplastic left heart (HP:0004383) | 2.11559783 |
| 65 | Absent thumb (HP:0009777) | 2.10598224 |
| 66 | Chronic sinusitis (HP:0011109) | 2.10420345 |
| 67 | Generalized aminoaciduria (HP:0002909) | 2.08863412 |
| 68 | Pancreatic cysts (HP:0001737) | 2.08072557 |
| 69 | Microvesicular hepatic steatosis (HP:0001414) | 2.04117858 |
| 70 | Congenital stationary night blindness (HP:0007642) | 2.03584783 |
| 71 | Lactic acidosis (HP:0003128) | 2.03355531 |
| 72 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.02018076 |
| 73 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.02018076 |
| 74 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.01694852 |
| 75 | Hyperphosphaturia (HP:0003109) | 1.99465959 |
| 76 | Constricted visual fields (HP:0001133) | 1.97455449 |
| 77 | Porencephaly (HP:0002132) | 1.94997434 |
| 78 | Abnormality of methionine metabolism (HP:0010901) | 1.92381472 |
| 79 | Central scotoma (HP:0000603) | 1.91791292 |
| 80 | Hydroureter (HP:0000072) | 1.89482783 |
| 81 | Megaloblastic anemia (HP:0001889) | 1.88762523 |
| 82 | Septate vagina (HP:0001153) | 1.86462735 |
| 83 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.86183446 |
| 84 | Increased serum lactate (HP:0002151) | 1.85811027 |
| 85 | Postaxial foot polydactyly (HP:0001830) | 1.84870957 |
| 86 | Partial duplication of thumb phalanx (HP:0009944) | 1.84298047 |
| 87 | Abnormality of DNA repair (HP:0003254) | 1.81487954 |
| 88 | Ketosis (HP:0001946) | 1.80977616 |
| 89 | Exercise intolerance (HP:0003546) | 1.80063078 |
| 90 | Hyperglycinuria (HP:0003108) | 1.78235118 |
| 91 | Hypoplastic heart (HP:0001961) | 1.77633095 |
| 92 | Duplication of thumb phalanx (HP:0009942) | 1.75796944 |
| 93 | Lethargy (HP:0001254) | 1.75768840 |
| 94 | Dicarboxylic aciduria (HP:0003215) | 1.75211442 |
| 95 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.75211442 |
| 96 | Abolished electroretinogram (ERG) (HP:0000550) | 1.73035515 |
| 97 | Increased muscle lipid content (HP:0009058) | 1.72815564 |
| 98 | Febrile seizures (HP:0002373) | 1.72525421 |
| 99 | Ketoacidosis (HP:0001993) | 1.72514911 |
| 100 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.71856280 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28 | 2.87919955 |
| 2 | STK16 | 2.87733057 |
| 3 | TXK | 2.80332293 |
| 4 | NUAK1 | 2.78974509 |
| 5 | WNK3 | 2.70767489 |
| 6 | MAP4K2 | 2.68348468 |
| 7 | SRPK1 | 2.66324629 |
| 8 | NEK1 | 2.53569203 |
| 9 | BMPR2 | 2.49911982 |
| 10 | INSRR | 2.35415127 |
| 11 | VRK2 | 2.33122109 |
| 12 | WNK4 | 2.18502193 |
| 13 | TLK1 | 2.14584746 |
| 14 | PASK | 1.88798728 |
| 15 | EPHB1 | 1.87512064 |
| 16 | DYRK2 | 1.78820475 |
| 17 | PHKG2 | 1.66477274 |
| 18 | PHKG1 | 1.66477274 |
| 19 | STK39 | 1.60443395 |
| 20 | PINK1 | 1.59128468 |
| 21 | VRK1 | 1.59116619 |
| 22 | ZAK | 1.51973512 |
| 23 | TIE1 | 1.50682871 |
| 24 | FRK | 1.47960323 |
| 25 | MAP2K2 | 1.43732845 |
| 26 | CDK19 | 1.40501417 |
| 27 | MARK1 | 1.40244079 |
| 28 | MAP3K12 | 1.39164053 |
| 29 | EPHB2 | 1.38620389 |
| 30 | BRAF | 1.24447216 |
| 31 | OXSR1 | 1.22635636 |
| 32 | EIF2AK3 | 1.20206188 |
| 33 | DAPK1 | 1.17364770 |
| 34 | TESK1 | 1.16243011 |
| 35 | RPS6KA5 | 1.14173614 |
| 36 | GRK1 | 1.11121495 |
| 37 | TNK2 | 1.08379385 |
| 38 | ADRBK2 | 1.02605560 |
| 39 | IKBKE | 1.00252640 |
| 40 | TAOK3 | 0.98423034 |
| 41 | NME1 | 0.97624968 |
| 42 | CCNB1 | 0.94778657 |
| 43 | LIMK1 | 0.92847877 |
| 44 | CAMK1 | 0.90465433 |
| 45 | MAPK13 | 0.88445429 |
| 46 | IRAK2 | 0.87234060 |
| 47 | PIK3CA | 0.86511842 |
| 48 | PLK3 | 0.79005486 |
| 49 | IKBKB | 0.78202800 |
| 50 | MST4 | 0.77761354 |
| 51 | ILK | 0.77444027 |
| 52 | PRKCG | 0.76244743 |
| 53 | WNK1 | 0.76074374 |
| 54 | PNCK | 0.75700766 |
| 55 | RPS6KA4 | 0.72672652 |
| 56 | KIT | 0.72144896 |
| 57 | RIPK4 | 0.71803331 |
| 58 | DAPK3 | 0.69975849 |
| 59 | CDK8 | 0.67726819 |
| 60 | IRAK1 | 0.67140664 |
| 61 | PIK3CG | 0.65540583 |
| 62 | MINK1 | 0.62649321 |
| 63 | OBSCN | 0.60571929 |
| 64 | SYK | 0.59580285 |
| 65 | CSF1R | 0.58983718 |
| 66 | RPS6KA6 | 0.58026351 |
| 67 | LATS1 | 0.54436930 |
| 68 | PAK3 | 0.54040352 |
| 69 | ABL2 | 0.53158554 |
| 70 | MYLK | 0.53145505 |
| 71 | DAPK2 | 0.51623934 |
| 72 | PKN1 | 0.50794356 |
| 73 | CASK | 0.50793676 |
| 74 | ERBB2 | 0.49002989 |
| 75 | CAMKK1 | 0.47345748 |
| 76 | NME2 | 0.47234987 |
| 77 | CDK3 | 0.47216371 |
| 78 | KSR1 | 0.46852008 |
| 79 | PLK4 | 0.46752000 |
| 80 | BCKDK | 0.45245752 |
| 81 | DYRK1A | 0.45131494 |
| 82 | CSNK1G3 | 0.44328611 |
| 83 | RPS6KC1 | 0.44295276 |
| 84 | RPS6KL1 | 0.44295276 |
| 85 | NTRK3 | 0.43880666 |
| 86 | TEC | 0.43073112 |
| 87 | TGFBR1 | 0.42236651 |
| 88 | PRKACA | 0.40196121 |
| 89 | PRKG1 | 0.39546755 |
| 90 | CHEK2 | 0.39422506 |
| 91 | CSNK2A2 | 0.39392101 |
| 92 | EPHA4 | 0.38277516 |
| 93 | CAMK1G | 0.37843251 |
| 94 | PLK2 | 0.37385333 |
| 95 | CAMK2A | 0.36666081 |
| 96 | IGF1R | 0.36220092 |
| 97 | EGFR | 0.35464063 |
| 98 | CSNK1A1L | 0.35083538 |
| 99 | CSNK2A1 | 0.35047934 |
| 100 | MARK3 | 0.34717778 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.39411685 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.77601876 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.46511657 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.99387237 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.12967374 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 3.08134009 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.98263246 |
| 8 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.95156955 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.73582901 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.58319657 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.56490378 |
| 12 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.54074035 |
| 13 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.82703979 |
| 14 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.73252250 |
| 15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.71637077 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.69089002 |
| 17 | Allograft rejection_Homo sapiens_hsa05330 | 1.63146782 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.53860769 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.39075634 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.36519863 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.34871178 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.34456179 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.33137635 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.22644079 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.22401302 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17781087 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.17535106 |
| 28 | Sulfur relay system_Homo sapiens_hsa04122 | 1.14529620 |
| 29 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.12795648 |
| 30 | Mismatch repair_Homo sapiens_hsa03430 | 1.11105625 |
| 31 | Nicotine addiction_Homo sapiens_hsa05033 | 1.10345619 |
| 32 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.02023552 |
| 33 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.00645041 |
| 34 | Olfactory transduction_Homo sapiens_hsa04740 | 0.89753945 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.89631844 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.85009982 |
| 37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.82469359 |
| 38 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.80079828 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.79435768 |
| 40 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.77662967 |
| 41 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.74491666 |
| 42 | Mineral absorption_Homo sapiens_hsa04978 | 0.73770670 |
| 43 | Morphine addiction_Homo sapiens_hsa05032 | 0.73714754 |
| 44 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.72311269 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.69964994 |
| 46 | Insulin secretion_Homo sapiens_hsa04911 | 0.68973213 |
| 47 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67743374 |
| 48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.65362381 |
| 49 | GABAergic synapse_Homo sapiens_hsa04727 | 0.64871595 |
| 50 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.64206182 |
| 51 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.63946172 |
| 52 | Purine metabolism_Homo sapiens_hsa00230 | 0.62554875 |
| 53 | RNA transport_Homo sapiens_hsa03013 | 0.58712131 |
| 54 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.58195913 |
| 55 | Salivary secretion_Homo sapiens_hsa04970 | 0.56473051 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.55633186 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.54418823 |
| 58 | Viral myocarditis_Homo sapiens_hsa05416 | 0.53615218 |
| 59 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.52548033 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51461801 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48876307 |
| 62 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.48576787 |
| 63 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48329371 |
| 64 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.47301689 |
| 65 | Taste transduction_Homo sapiens_hsa04742 | 0.46870814 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.45890306 |
| 67 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.45462406 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45399679 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44500394 |
| 70 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43243980 |
| 71 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.42930273 |
| 72 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.42640806 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.41443263 |
| 74 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.41332861 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39951731 |
| 76 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39366342 |
| 77 | Circadian entrainment_Homo sapiens_hsa04713 | 0.37246790 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36026669 |
| 79 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.34543466 |
| 80 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.34238488 |
| 81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.33911344 |
| 82 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.31718339 |
| 83 | Phagosome_Homo sapiens_hsa04145 | 0.29062281 |
| 84 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.28766570 |
| 85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.28560929 |
| 86 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.28001933 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.26806979 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.25575000 |
| 89 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.25471978 |
| 90 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.24222334 |
| 91 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.23378886 |
| 92 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.22799969 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.21983455 |
| 94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.21136025 |
| 95 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.19787003 |
| 96 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.19171660 |
| 97 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.19036548 |
| 98 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.18097438 |
| 99 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.16898473 |
| 100 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.13880143 |

