

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of protein deacetylation (GO:0090312) | 6.79266298 |
| 2 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 6.51919514 |
| 3 | telomere maintenance via semi-conservative replication (GO:0032201) | 6.27668615 |
| 4 | DNA strand elongation (GO:0022616) | 5.69236442 |
| 5 | DNA replication initiation (GO:0006270) | 5.56120217 |
| 6 | DNA strand elongation involved in DNA replication (GO:0006271) | 5.36329999 |
| 7 | telomere maintenance via recombination (GO:0000722) | 5.35730656 |
| 8 | mitotic recombination (GO:0006312) | 5.30053839 |
| 9 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 5.21723355 |
| 10 | somite rostral/caudal axis specification (GO:0032525) | 5.16364746 |
| 11 | RNA destabilization (GO:0050779) | 5.12928969 |
| 12 | forebrain neuron development (GO:0021884) | 5.12792928 |
| 13 | DNA unwinding involved in DNA replication (GO:0006268) | 5.07280077 |
| 14 | microtubule depolymerization (GO:0007019) | 4.86452415 |
| 15 | regulation of meiosis I (GO:0060631) | 4.85669149 |
| 16 | DNA ligation (GO:0006266) | 4.66397427 |
| 17 | response to misfolded protein (GO:0051788) | 4.49601424 |
| 18 | DNA synthesis involved in DNA repair (GO:0000731) | 4.41833228 |
| 19 | regulation of protein deacetylation (GO:0090311) | 4.32673380 |
| 20 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.18593636 |
| 21 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.18593636 |
| 22 | cellular response to nitric oxide (GO:0071732) | 4.17849966 |
| 23 | membrane budding (GO:0006900) | 4.17814467 |
| 24 | response to folic acid (GO:0051593) | 4.16577570 |
| 25 | retinal ganglion cell axon guidance (GO:0031290) | 4.15712053 |
| 26 | cell wall macromolecule catabolic process (GO:0016998) | 4.02264360 |
| 27 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 3.96253138 |
| 28 | short-term memory (GO:0007614) | 3.95619516 |
| 29 | neuronal stem cell maintenance (GO:0097150) | 3.94009190 |
| 30 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.89569098 |
| 31 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 3.89500599 |
| 32 | mitotic sister chromatid segregation (GO:0000070) | 3.89309341 |
| 33 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 3.85889742 |
| 34 | positive regulation of dendritic spine development (GO:0060999) | 3.81403209 |
| 35 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.80564186 |
| 36 | synaptic transmission, cholinergic (GO:0007271) | 3.80023784 |
| 37 | apoptotic process involved in development (GO:1902742) | 3.72562168 |
| 38 | sister chromatid segregation (GO:0000819) | 3.71513717 |
| 39 | positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 3.69820390 |
| 40 | microtubule polymerization or depolymerization (GO:0031109) | 3.69749936 |
| 41 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.67193135 |
| 42 | interkinetic nuclear migration (GO:0022027) | 3.63775435 |
| 43 | cell wall macromolecule metabolic process (GO:0044036) | 3.63623331 |
| 44 | telomere maintenance via telomere lengthening (GO:0010833) | 3.55570828 |
| 45 | hemoglobin metabolic process (GO:0020027) | 3.51862567 |
| 46 | regulation of penile erection (GO:0060405) | 3.42707876 |
| 47 | sister chromatid cohesion (GO:0007062) | 3.42396724 |
| 48 | translesion synthesis (GO:0019985) | 3.37193758 |
| 49 | DNA replication checkpoint (GO:0000076) | 3.36569111 |
| 50 | blastocyst development (GO:0001824) | 3.30767824 |
| 51 | ketone body metabolic process (GO:1902224) | 3.25700315 |
| 52 | negative regulation of microtubule polymerization (GO:0031115) | 3.24237928 |
| 53 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.18081868 |
| 54 | meiotic nuclear division (GO:0007126) | 3.17968598 |
| 55 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.16106735 |
| 56 | regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 3.15929405 |
| 57 | CENP-A containing nucleosome assembly (GO:0034080) | 3.15085414 |
| 58 | cellular ketone body metabolic process (GO:0046950) | 3.12741643 |
| 59 | cellular response to reactive nitrogen species (GO:1902170) | 3.12304568 |
| 60 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.10397466 |
| 61 | behavioral response to nicotine (GO:0035095) | 3.07566089 |
| 62 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 3.05637215 |
| 63 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 3.03998488 |
| 64 | circadian sleep/wake cycle process (GO:0022410) | 3.02994184 |
| 65 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.00603828 |
| 66 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.95747961 |
| 67 | negative regulation of multicellular organism growth (GO:0040015) | 2.94436802 |
| 68 | negative regulation of macroautophagy (GO:0016242) | 2.91412241 |
| 69 | protein localization to cilium (GO:0061512) | 2.88144926 |
| 70 | removal of superoxide radicals (GO:0019430) | 2.87505903 |
| 71 | cellular response to superoxide (GO:0071451) | 2.87505903 |
| 72 | cellular response to oxygen radical (GO:0071450) | 2.87505903 |
| 73 | chromatin remodeling at centromere (GO:0031055) | 2.86929503 |
| 74 | DNA biosynthetic process (GO:0071897) | 2.85698210 |
| 75 | male meiosis (GO:0007140) | 2.83011762 |
| 76 | tryptophan metabolic process (GO:0006568) | 2.81477804 |
| 77 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.80347956 |
| 78 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.80260032 |
| 79 | alkaloid metabolic process (GO:0009820) | 2.78682355 |
| 80 | central nervous system neuron development (GO:0021954) | 2.78258632 |
| 81 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.76337427 |
| 82 | gastrulation with mouth forming second (GO:0001702) | 2.76286396 |
| 83 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 2.75800810 |
| 84 | positive regulation of histone deacetylation (GO:0031065) | 2.75195032 |
| 85 | interferon-gamma production (GO:0032609) | 2.75067565 |
| 86 | carnitine shuttle (GO:0006853) | 2.74181751 |
| 87 | nucleus localization (GO:0051647) | 2.71739764 |
| 88 | DNA damage response, detection of DNA damage (GO:0042769) | 2.71323428 |
| 89 | layer formation in cerebral cortex (GO:0021819) | 2.71246429 |
| 90 | microtubule nucleation (GO:0007020) | 2.70929106 |
| 91 | positive regulation of protein homodimerization activity (GO:0090073) | 2.70719029 |
| 92 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.68447576 |
| 93 | telomere maintenance (GO:0000723) | 2.67582513 |
| 94 | regulation of DNA endoreduplication (GO:0032875) | 2.66610841 |
| 95 | indolalkylamine metabolic process (GO:0006586) | 2.66307391 |
| 96 | telomere organization (GO:0032200) | 2.65560333 |
| 97 | ectodermal placode formation (GO:0060788) | 2.65057372 |
| 98 | kinetochore organization (GO:0051383) | 2.65009571 |
| 99 | termination of RNA polymerase II transcription (GO:0006369) | 2.64025721 |
| 100 | Peyers patch development (GO:0048541) | 2.63509336 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 7.43050801 |
| 2 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.33212512 |
| 3 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.41017978 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.98644919 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.92168970 |
| 6 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.89271804 |
| 7 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.64895472 |
| 8 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.52509980 |
| 9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.49012560 |
| 10 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.44190970 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.18781334 |
| 12 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 2.15850326 |
| 13 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 2.06551419 |
| 14 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 2.04116380 |
| 15 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.01746630 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 2.01095299 |
| 17 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.98018356 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.96619795 |
| 19 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.93427014 |
| 20 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.93160821 |
| 21 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.87777599 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85053297 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.81839580 |
| 24 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.80622025 |
| 25 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.79948413 |
| 26 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.77610149 |
| 27 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.74061209 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.70899482 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.65104555 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.64857402 |
| 31 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.60518997 |
| 32 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.58220837 |
| 33 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.54785778 |
| 34 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.49621099 |
| 35 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.48983198 |
| 36 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.48771762 |
| 37 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.47584321 |
| 38 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.46488653 |
| 39 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.46273707 |
| 40 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.45711295 |
| 41 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.45313537 |
| 42 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.42369345 |
| 43 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.42232517 |
| 44 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.39266343 |
| 45 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.38873311 |
| 46 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.36102127 |
| 47 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.30803268 |
| 48 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29667264 |
| 49 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.28559510 |
| 50 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.28559510 |
| 51 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.27818366 |
| 52 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.23304976 |
| 53 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.22139076 |
| 54 | VDR_22108803_ChIP-Seq_LS180_Human | 1.17776859 |
| 55 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.17587739 |
| 56 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.17241419 |
| 57 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.16416670 |
| 58 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.15450298 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14927142 |
| 60 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.14491894 |
| 61 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.10819791 |
| 62 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.10819791 |
| 63 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.07558305 |
| 64 | NCOR_22424771_ChIP-Seq_293T_Human | 1.07085464 |
| 65 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.06149993 |
| 66 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05629407 |
| 67 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03517076 |
| 68 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.03076520 |
| 69 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.01501383 |
| 70 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.00154222 |
| 71 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.99858011 |
| 72 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.99572194 |
| 73 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.99514935 |
| 74 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.99208147 |
| 75 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.99037640 |
| 76 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.96277564 |
| 77 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.95246917 |
| 78 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.95210163 |
| 79 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.94584120 |
| 80 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.94497411 |
| 81 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.94345553 |
| 82 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 0.93677757 |
| 83 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92998042 |
| 84 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.90804320 |
| 85 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.88131701 |
| 86 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.86939042 |
| 87 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.85959223 |
| 88 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.85749491 |
| 89 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.85642715 |
| 90 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.83444174 |
| 91 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.82978988 |
| 92 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.82333329 |
| 93 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.81430677 |
| 94 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.81049640 |
| 95 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.80107918 |
| 96 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.79889690 |
| 97 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.79159009 |
| 98 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.78299340 |
| 99 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.77367053 |
| 100 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.77095759 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 5.96640277 |
| 2 | MP0003890_abnormal_embryonic-extraembry | 4.50786765 |
| 3 | MP0000516_abnormal_urinary_system | 4.23604215 |
| 4 | MP0005367_renal/urinary_system_phenotyp | 4.23604215 |
| 5 | MP0000372_irregular_coat_pigmentation | 4.05956791 |
| 6 | MP0000569_abnormal_digit_pigmentation | 4.05563882 |
| 7 | MP0005670_abnormal_white_adipose | 3.68030837 |
| 8 | MP0003136_yellow_coat_color | 3.37819594 |
| 9 | MP0003806_abnormal_nucleotide_metabolis | 3.37505999 |
| 10 | MP0009697_abnormal_copulation | 2.96143235 |
| 11 | MP0005171_absent_coat_pigmentation | 2.87987559 |
| 12 | MP0010094_abnormal_chromosome_stability | 2.59635922 |
| 13 | MP0002234_abnormal_pharynx_morphology | 2.34173484 |
| 14 | MP0002102_abnormal_ear_morphology | 2.27031585 |
| 15 | MP0005174_abnormal_tail_pigmentation | 2.22038469 |
| 16 | MP0001986_abnormal_taste_sensitivity | 2.18850575 |
| 17 | MP0002249_abnormal_larynx_morphology | 2.09777915 |
| 18 | MP0005266_abnormal_metabolism | 2.08973359 |
| 19 | MP0000015_abnormal_ear_pigmentation | 2.05419987 |
| 20 | MP0002822_catalepsy | 1.89412095 |
| 21 | MP0003111_abnormal_nucleus_morphology | 1.86482662 |
| 22 | MP0000566_synostosis | 1.85601736 |
| 23 | MP0008961_abnormal_basal_metabolism | 1.75740755 |
| 24 | MP0003077_abnormal_cell_cycle | 1.52773860 |
| 25 | MP0003880_abnormal_central_pattern | 1.52445222 |
| 26 | MP0004142_abnormal_muscle_tone | 1.51184985 |
| 27 | MP0003119_abnormal_digestive_system | 1.49634052 |
| 28 | MP0003693_abnormal_embryo_hatching | 1.47068648 |
| 29 | MP0003879_abnormal_hair_cell | 1.38358343 |
| 30 | MP0010368_abnormal_lymphatic_system | 1.36886220 |
| 31 | MP0002938_white_spotting | 1.36244182 |
| 32 | MP0003938_abnormal_ear_development | 1.29159328 |
| 33 | MP0000537_abnormal_urethra_morphology | 1.27518641 |
| 34 | MP0002098_abnormal_vibrissa_morphology | 1.27480130 |
| 35 | MP0005409_darkened_coat_color | 1.27286476 |
| 36 | MP0000371_diluted_coat_color | 1.26749349 |
| 37 | MP0000534_abnormal_ureter_morphology | 1.26571127 |
| 38 | MP0006035_abnormal_mitochondrial_morpho | 1.24001340 |
| 39 | MP0003943_abnormal_hepatobiliary_system | 1.23179638 |
| 40 | MP0000751_myopathy | 1.20073785 |
| 41 | MP0001501_abnormal_sleep_pattern | 1.19975246 |
| 42 | MP0008007_abnormal_cellular_replicative | 1.17739670 |
| 43 | MP0008932_abnormal_embryonic_tissue | 1.16792027 |
| 44 | MP0002132_abnormal_respiratory_system | 1.13864507 |
| 45 | MP0000955_abnormal_spinal_cord | 1.12696623 |
| 46 | MP0009379_abnormal_foot_pigmentation | 1.10637413 |
| 47 | MP0002095_abnormal_skin_pigmentation | 1.07501370 |
| 48 | MP0000383_abnormal_hair_follicle | 1.01441462 |
| 49 | MP0004133_heterotaxia | 0.94581250 |
| 50 | MP0005423_abnormal_somatic_nervous | 0.92606489 |
| 51 | MP0002075_abnormal_coat/hair_pigmentati | 0.91934669 |
| 52 | MP0002009_preneoplasia | 0.91197980 |
| 53 | MP0009278_abnormal_bone_marrow | 0.91093026 |
| 54 | MP0000678_abnormal_parathyroid_gland | 0.90709765 |
| 55 | MP0009046_muscle_twitch | 0.89517709 |
| 56 | MP0002736_abnormal_nociception_after | 0.89192360 |
| 57 | MP0001346_abnormal_lacrimal_gland | 0.88539422 |
| 58 | MP0002184_abnormal_innervation | 0.87489615 |
| 59 | MP0005076_abnormal_cell_differentiation | 0.84192389 |
| 60 | MP0004957_abnormal_blastocyst_morpholog | 0.84180552 |
| 61 | MP0002970_abnormal_white_adipose | 0.84167404 |
| 62 | MP0001486_abnormal_startle_reflex | 0.83686496 |
| 63 | MP0000631_abnormal_neuroendocrine_gland | 0.83370183 |
| 64 | MP0003937_abnormal_limbs/digits/tail_de | 0.83118276 |
| 65 | MP0008058_abnormal_DNA_repair | 0.82333470 |
| 66 | MP0003183_abnormal_peptide_metabolism | 0.82306386 |
| 67 | MP0002084_abnormal_developmental_patter | 0.81192802 |
| 68 | MP0003186_abnormal_redox_activity | 0.79958606 |
| 69 | MP0005376_homeostasis/metabolism_phenot | 0.79056101 |
| 70 | MP0001672_abnormal_embryogenesis/_devel | 0.78819355 |
| 71 | MP0005380_embryogenesis_phenotype | 0.78819355 |
| 72 | MP0001286_abnormal_eye_development | 0.76919887 |
| 73 | MP0004742_abnormal_vestibular_system | 0.75135156 |
| 74 | MP0002210_abnormal_sex_determination | 0.74590603 |
| 75 | MP0009115_abnormal_fat_cell | 0.70373392 |
| 76 | MP0001697_abnormal_embryo_size | 0.69329557 |
| 77 | MP0000681_abnormal_thyroid_gland | 0.66600360 |
| 78 | MP0001145_abnormal_male_reproductive | 0.66308551 |
| 79 | MP0003984_embryonic_growth_retardation | 0.64248706 |
| 80 | MP0003567_abnormal_fetal_cardiomyocyte | 0.62434644 |
| 81 | MP0002932_abnormal_joint_morphology | 0.62059198 |
| 82 | MP0003221_abnormal_cardiomyocyte_apopto | 0.61358317 |
| 83 | MP0002088_abnormal_embryonic_growth/wei | 0.60505337 |
| 84 | MP0003632_abnormal_nervous_system | 0.59414024 |
| 85 | MP0002751_abnormal_autonomic_nervous | 0.59008121 |
| 86 | MP0001730_embryonic_growth_arrest | 0.58764087 |
| 87 | MP0010678_abnormal_skin_adnexa | 0.58693439 |
| 88 | MP0002114_abnormal_axial_skeleton | 0.58400944 |
| 89 | MP0003936_abnormal_reproductive_system | 0.57865965 |
| 90 | MP0002735_abnormal_chemical_nociception | 0.56337283 |
| 91 | MP0004197_abnormal_fetal_growth/weight/ | 0.56059269 |
| 92 | MP0002085_abnormal_embryonic_tissue | 0.56007995 |
| 93 | MP0000350_abnormal_cell_proliferation | 0.55500863 |
| 94 | MP0003698_abnormal_male_reproductive | 0.54650476 |
| 95 | MP0003861_abnormal_nervous_system | 0.54134220 |
| 96 | MP0001324_abnormal_eye_pigmentation | 0.53968973 |
| 97 | MP0004043_abnormal_pH_regulation | 0.52972098 |
| 98 | MP0002837_dystrophic_cardiac_calcinosis | 0.52006795 |
| 99 | MP0001186_pigmentation_phenotype | 0.51813676 |
| 100 | MP0002152_abnormal_brain_morphology | 0.51414453 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Failure to thrive in infancy (HP:0001531) | 5.57928629 |
| 2 | Split foot (HP:0001839) | 4.57524588 |
| 3 | Hypoplastic pelvis (HP:0008839) | 4.34666814 |
| 4 | Febrile seizures (HP:0002373) | 4.04011911 |
| 5 | Rib fusion (HP:0000902) | 4.03267754 |
| 6 | Severe global developmental delay (HP:0011344) | 3.72012908 |
| 7 | Focal motor seizures (HP:0011153) | 3.53285450 |
| 8 | Ankle clonus (HP:0011448) | 3.47311031 |
| 9 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.42217600 |
| 10 | Agammaglobulinemia (HP:0004432) | 3.29379679 |
| 11 | Hypoplasia of the pons (HP:0012110) | 3.08354114 |
| 12 | Breast hypoplasia (HP:0003187) | 3.07305536 |
| 13 | Chromsome breakage (HP:0040012) | 2.97137977 |
| 14 | Abnormality of homocysteine metabolism (HP:0010919) | 2.96917489 |
| 15 | Homocystinuria (HP:0002156) | 2.96917489 |
| 16 | Abnormality of methionine metabolism (HP:0010901) | 2.93741249 |
| 17 | High anterior hairline (HP:0009890) | 2.86410282 |
| 18 | Shoulder girdle muscle weakness (HP:0003547) | 2.85198365 |
| 19 | Small hand (HP:0200055) | 2.77949446 |
| 20 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.74262808 |
| 21 | Abnormal protein glycosylation (HP:0012346) | 2.69350918 |
| 22 | Abnormal glycosylation (HP:0012345) | 2.69350918 |
| 23 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.69350918 |
| 24 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.69350918 |
| 25 | Limb-girdle muscle atrophy (HP:0003797) | 2.67056499 |
| 26 | Broad alveolar ridges (HP:0000187) | 2.59727573 |
| 27 | Renal hypoplasia (HP:0000089) | 2.55454435 |
| 28 | Intestinal atresia (HP:0011100) | 2.54411972 |
| 29 | Alacrima (HP:0000522) | 2.53140357 |
| 30 | Oligodactyly (HP:0012165) | 2.51436369 |
| 31 | Poor coordination (HP:0002370) | 2.51187455 |
| 32 | Poor head control (HP:0002421) | 2.48566265 |
| 33 | Median cleft lip (HP:0000161) | 2.47841139 |
| 34 | Abnormality of the pons (HP:0007361) | 2.45259606 |
| 35 | Orthostatic hypotension (HP:0001278) | 2.40428643 |
| 36 | Volvulus (HP:0002580) | 2.40231153 |
| 37 | Midline defect of the nose (HP:0004122) | 2.39039204 |
| 38 | Deeply set eye (HP:0000490) | 2.38139535 |
| 39 | Abnormality of secondary sexual hair (HP:0009888) | 2.33373083 |
| 40 | Abnormality of the axillary hair (HP:0100134) | 2.33373083 |
| 41 | Rimmed vacuoles (HP:0003805) | 2.33021533 |
| 42 | Triphalangeal thumb (HP:0001199) | 2.32897984 |
| 43 | Congenital, generalized hypertrichosis (HP:0004540) | 2.31718328 |
| 44 | Meckel diverticulum (HP:0002245) | 2.31412947 |
| 45 | Abnormality of the ileum (HP:0001549) | 2.26476420 |
| 46 | Dysautonomia (HP:0002459) | 2.25477077 |
| 47 | Abnormal lung lobation (HP:0002101) | 2.24663402 |
| 48 | Birth length less than 3rd percentile (HP:0003561) | 2.23962091 |
| 49 | Absent radius (HP:0003974) | 2.19868459 |
| 50 | Hemorrhage of the eye (HP:0011885) | 2.18956240 |
| 51 | Progressive external ophthalmoplegia (HP:0000590) | 2.18771230 |
| 52 | Abnormal auditory evoked potentials (HP:0006958) | 2.15676751 |
| 53 | Absent thumb (HP:0009777) | 2.13130771 |
| 54 | Duodenal stenosis (HP:0100867) | 2.12898790 |
| 55 | Small intestinal stenosis (HP:0012848) | 2.12898790 |
| 56 | Amyotrophic lateral sclerosis (HP:0007354) | 2.12078601 |
| 57 | Methylmalonic aciduria (HP:0012120) | 2.11590890 |
| 58 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.11097336 |
| 59 | Central scotoma (HP:0000603) | 2.10963022 |
| 60 | Proximal placement of thumb (HP:0009623) | 2.10032474 |
| 61 | Overlapping toe (HP:0001845) | 2.09706945 |
| 62 | Absent forearm bone (HP:0003953) | 2.08712326 |
| 63 | Aplasia involving forearm bones (HP:0009822) | 2.08712326 |
| 64 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.04813801 |
| 65 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.02734784 |
| 66 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.02734784 |
| 67 | Esophageal atresia (HP:0002032) | 2.02717559 |
| 68 | Papillary thyroid carcinoma (HP:0002895) | 2.02283636 |
| 69 | Supernumerary spleens (HP:0009799) | 2.02161287 |
| 70 | Methylmalonic acidemia (HP:0002912) | 1.96987439 |
| 71 | Facial hemangioma (HP:0000329) | 1.96330110 |
| 72 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.93920182 |
| 73 | Large earlobe (HP:0009748) | 1.93747164 |
| 74 | Hypothermia (HP:0002045) | 1.93223777 |
| 75 | Decreased lacrimation (HP:0000633) | 1.92752278 |
| 76 | Scanning speech (HP:0002168) | 1.91867887 |
| 77 | Deviation of the thumb (HP:0009603) | 1.90676569 |
| 78 | Pelvic girdle muscle weakness (HP:0003749) | 1.89678759 |
| 79 | External ophthalmoplegia (HP:0000544) | 1.88584318 |
| 80 | Coarctation of aorta (HP:0001680) | 1.88321274 |
| 81 | Type I transferrin isoform profile (HP:0003642) | 1.86269335 |
| 82 | Multiple enchondromatosis (HP:0005701) | 1.85162333 |
| 83 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.85112139 |
| 84 | Dicarboxylic aciduria (HP:0003215) | 1.85112139 |
| 85 | Exercise-induced myalgia (HP:0003738) | 1.84500278 |
| 86 | Gastrointestinal atresia (HP:0002589) | 1.84465996 |
| 87 | Abnormality of cochlea (HP:0000375) | 1.84195592 |
| 88 | Absent speech (HP:0001344) | 1.82886530 |
| 89 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.80912394 |
| 90 | Hypoplastic female external genitalia (HP:0012815) | 1.80450773 |
| 91 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.79300889 |
| 92 | Abnormality of the duodenum (HP:0002246) | 1.77905502 |
| 93 | Woolly hair (HP:0002224) | 1.77615435 |
| 94 | Abnormality of the parathyroid morphology (HP:0011766) | 1.76631552 |
| 95 | Abnormality of the lacrimal duct (HP:0011481) | 1.76441083 |
| 96 | Embryonal renal neoplasm (HP:0011794) | 1.76029567 |
| 97 | Low anterior hairline (HP:0000294) | 1.75432349 |
| 98 | Nasolacrimal duct obstruction (HP:0000579) | 1.74002600 |
| 99 | Limited elbow extension (HP:0001377) | 1.73883114 |
| 100 | Hyperkalemia (HP:0002153) | 1.73187346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAF1 | 7.09161672 |
| 2 | FGFR3 | 4.64916304 |
| 3 | CDC7 | 3.18570029 |
| 4 | MAP3K4 | 2.84472728 |
| 5 | UHMK1 | 2.50657773 |
| 6 | MAP4K2 | 2.47555184 |
| 7 | DYRK1A | 2.41334701 |
| 8 | PNCK | 2.40625363 |
| 9 | MAPK13 | 2.35633671 |
| 10 | MAP2K7 | 2.32115132 |
| 11 | MAP3K6 | 2.27501347 |
| 12 | PBK | 2.25162467 |
| 13 | CAMK1G | 2.22469079 |
| 14 | ZAK | 2.16477840 |
| 15 | LATS1 | 2.09463228 |
| 16 | WEE1 | 1.87060035 |
| 17 | NUAK1 | 1.86991226 |
| 18 | CAMK1D | 1.60809267 |
| 19 | NEK1 | 1.52578138 |
| 20 | MAP2K4 | 1.52149115 |
| 21 | CAMK4 | 1.46631795 |
| 22 | ATR | 1.38908151 |
| 23 | SRPK1 | 1.36841779 |
| 24 | CDK8 | 1.36492577 |
| 25 | TAOK1 | 1.36216449 |
| 26 | CCNB1 | 1.26544561 |
| 27 | CSF1R | 1.23050944 |
| 28 | BUB1 | 1.19722923 |
| 29 | WNK3 | 1.18159920 |
| 30 | TRIM28 | 1.17480750 |
| 31 | BCR | 1.10832854 |
| 32 | CHEK2 | 1.08848074 |
| 33 | RIPK4 | 1.08610351 |
| 34 | DYRK3 | 1.08257754 |
| 35 | MATK | 1.06053762 |
| 36 | NEK2 | 0.96225707 |
| 37 | SGK1 | 0.90648866 |
| 38 | ERBB2 | 0.88692601 |
| 39 | BMX | 0.87035571 |
| 40 | EPHB2 | 0.82288418 |
| 41 | MAP2K3 | 0.80664387 |
| 42 | CDK7 | 0.78163120 |
| 43 | FGR | 0.78067490 |
| 44 | LATS2 | 0.76287511 |
| 45 | MARK1 | 0.75678820 |
| 46 | EEF2K | 0.74999000 |
| 47 | PLK4 | 0.71357420 |
| 48 | CSNK1E | 0.70518367 |
| 49 | CHEK1 | 0.69579016 |
| 50 | MST4 | 0.68395437 |
| 51 | PASK | 0.67660953 |
| 52 | CDK11A | 0.67470496 |
| 53 | MKNK1 | 0.67244911 |
| 54 | CDK4 | 0.63179157 |
| 55 | BRSK1 | 0.62919088 |
| 56 | AURKA | 0.62643393 |
| 57 | MAP3K5 | 0.60859208 |
| 58 | CDK1 | 0.59007378 |
| 59 | ATM | 0.58094090 |
| 60 | CDK15 | 0.57130659 |
| 61 | AURKB | 0.56456473 |
| 62 | CDK2 | 0.55963180 |
| 63 | TTK | 0.55216838 |
| 64 | KDR | 0.54093358 |
| 65 | PLK1 | 0.53691903 |
| 66 | CDK18 | 0.53546575 |
| 67 | PRKACB | 0.48843853 |
| 68 | BMPR1B | 0.48261885 |
| 69 | ERBB3 | 0.46967994 |
| 70 | TNK2 | 0.46174034 |
| 71 | CDK3 | 0.41316435 |
| 72 | INSR | 0.41015836 |
| 73 | CSNK2A1 | 0.40784541 |
| 74 | CDK14 | 0.39554401 |
| 75 | EGFR | 0.37948985 |
| 76 | MKNK2 | 0.37646309 |
| 77 | CAMK2A | 0.36122706 |
| 78 | GSK3B | 0.35972908 |
| 79 | DYRK1B | 0.35822056 |
| 80 | MARK2 | 0.35715066 |
| 81 | CDK9 | 0.34960811 |
| 82 | MAPKAPK3 | 0.34364234 |
| 83 | MAPK10 | 0.32674764 |
| 84 | NTRK1 | 0.31731306 |
| 85 | PRKCZ | 0.31615453 |
| 86 | MET | 0.30816736 |
| 87 | MAPK9 | 0.30359585 |
| 88 | RPS6KA4 | 0.29969700 |
| 89 | MAPK14 | 0.29685570 |
| 90 | PRKAA2 | 0.29048958 |
| 91 | CSNK2A2 | 0.27934107 |
| 92 | RET | 0.27522874 |
| 93 | CAMK2B | 0.27307379 |
| 94 | CDK6 | 0.26825091 |
| 95 | CSNK1A1 | 0.26409110 |
| 96 | TRPM7 | 0.26276208 |
| 97 | FLT3 | 0.25955247 |
| 98 | MINK1 | 0.24473376 |
| 99 | PRKACG | 0.23670353 |
| 100 | PRKDC | 0.23261861 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 5.82384120 |
| 2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.66519544 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 4.33456181 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 4.14534494 |
| 5 | Base excision repair_Homo sapiens_hsa03410 | 3.69188273 |
| 6 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 3.54836855 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.96757655 |
| 8 | Taste transduction_Homo sapiens_hsa04742 | 2.92824738 |
| 9 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.83799541 |
| 10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.17472669 |
| 11 | Spliceosome_Homo sapiens_hsa03040 | 2.07641207 |
| 12 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 2.06267868 |
| 13 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.05337028 |
| 14 | Cell cycle_Homo sapiens_hsa04110 | 1.90370941 |
| 15 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.89716971 |
| 16 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.88832567 |
| 17 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.85231274 |
| 18 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.66444012 |
| 19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.40873171 |
| 20 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.36663782 |
| 21 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.33144020 |
| 22 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.28595477 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.24924812 |
| 24 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.21385604 |
| 25 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.20725299 |
| 26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.19560438 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.13391902 |
| 28 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.09822968 |
| 29 | RNA transport_Homo sapiens_hsa03013 | 1.03022013 |
| 30 | RNA polymerase_Homo sapiens_hsa03020 | 0.95376685 |
| 31 | Nicotine addiction_Homo sapiens_hsa05033 | 0.94490315 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92751681 |
| 33 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.91345076 |
| 34 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.90579930 |
| 35 | Morphine addiction_Homo sapiens_hsa05032 | 0.89805012 |
| 36 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.88598858 |
| 37 | Huntingtons disease_Homo sapiens_hsa05016 | 0.87249693 |
| 38 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.85164423 |
| 39 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.83503863 |
| 40 | Alcoholism_Homo sapiens_hsa05034 | 0.80502499 |
| 41 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.75062775 |
| 42 | GABAergic synapse_Homo sapiens_hsa04727 | 0.73036673 |
| 43 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.71533066 |
| 44 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.63495628 |
| 45 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.62676637 |
| 46 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.62527574 |
| 47 | Circadian rhythm_Homo sapiens_hsa04710 | 0.61586541 |
| 48 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.59398415 |
| 49 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59277862 |
| 50 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.56997929 |
| 51 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.54147045 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53625151 |
| 53 | Parkinsons disease_Homo sapiens_hsa05012 | 0.53100259 |
| 54 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.52138037 |
| 55 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.52081295 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.51871370 |
| 57 | Ribosome_Homo sapiens_hsa03010 | 0.50400913 |
| 58 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.49901658 |
| 59 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.46781548 |
| 60 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.46748743 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43918815 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.40401716 |
| 63 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.39170235 |
| 64 | Peroxisome_Homo sapiens_hsa04146 | 0.37636775 |
| 65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.37253651 |
| 66 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.37187556 |
| 67 | Protein export_Homo sapiens_hsa03060 | 0.36313960 |
| 68 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.35606840 |
| 69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.35291925 |
| 70 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.33685398 |
| 71 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.32370385 |
| 72 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.31881312 |
| 73 | Histidine metabolism_Homo sapiens_hsa00340 | 0.29533272 |
| 74 | Axon guidance_Homo sapiens_hsa04360 | 0.29497062 |
| 75 | RNA degradation_Homo sapiens_hsa03018 | 0.28730186 |
| 76 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.28579793 |
| 77 | Circadian entrainment_Homo sapiens_hsa04713 | 0.28457872 |
| 78 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.27844171 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25334038 |
| 80 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.21391001 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.21078195 |
| 82 | Phototransduction_Homo sapiens_hsa04744 | 0.20984220 |
| 83 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.20755196 |
| 84 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.20669531 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.20312874 |
| 86 | Cocaine addiction_Homo sapiens_hsa05030 | 0.20159141 |
| 87 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.18377080 |
| 88 | Pertussis_Homo sapiens_hsa05133 | 0.18255757 |
| 89 | Proteasome_Homo sapiens_hsa03050 | 0.17734978 |
| 90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.17327336 |
| 91 | Basal transcription factors_Homo sapiens_hsa03022 | 0.17002625 |
| 92 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.15768613 |
| 93 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.14243955 |
| 94 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.12530333 |
| 95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.12060493 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.11025065 |
| 97 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.10449751 |
| 98 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.10337389 |
| 99 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.09679371 |
| 100 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.08835208 |

