RCN3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)7.22350254
2collagen fibril organization (GO:0030199)6.84435214
3bone trabecula formation (GO:0060346)6.02279555
4chondrocyte proliferation (GO:0035988)5.37710744
5virion attachment to host cell (GO:0019062)5.03629056
6adhesion of symbiont to host cell (GO:0044650)5.03629056
7collagen metabolic process (GO:0032963)4.73141712
8endodermal cell differentiation (GO:0035987)4.70104500
9cartilage development involved in endochondral bone morphogenesis (GO:0060351)4.65105088
10collagen catabolic process (GO:0030574)4.63476536
11sequestering of extracellular ligand from receptor (GO:0035581)4.60375184
12skin morphogenesis (GO:0043589)4.56102392
13type B pancreatic cell proliferation (GO:0044342)4.54503206
14keratan sulfate catabolic process (GO:0042340)4.40964582
15multicellular organismal macromolecule metabolic process (GO:0044259)4.40083889
16adhesion of symbiont to host (GO:0044406)4.35211618
17neuron projection extension involved in neuron projection guidance (GO:1902284)4.26762058
18axon extension involved in axon guidance (GO:0048846)4.26762058
19multicellular organismal catabolic process (GO:0044243)4.25061123
20extracellular fibril organization (GO:0043206)4.21981017
21peptidyl-proline hydroxylation (GO:0019511)4.15434550
22multicellular organismal metabolic process (GO:0044236)4.13352118
23planar cell polarity pathway involved in neural tube closure (GO:0090179)4.09573942
24regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.04646022
25barbed-end actin filament capping (GO:0051016)4.02967289
26basement membrane organization (GO:0071711)4.02705802
27fibril organization (GO:0097435)3.93836298
28extracellular matrix disassembly (GO:0022617)3.90769835
29outer ear morphogenesis (GO:0042473)3.84155020
30negative regulation of smooth muscle cell migration (GO:0014912)3.83201257
31cell migration involved in heart development (GO:0060973)3.78690878
32chondrocyte development (GO:0002063)3.76067326
33regulation of plasminogen activation (GO:0010755)3.72061827
34positive regulation of blood vessel endothelial cell migration (GO:0043536)3.66979725
35metanephric mesenchyme development (GO:0072075)3.65829596
36negative regulation of chondrocyte differentiation (GO:0032331)3.65587276
37regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.63909086
38maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.63062738
39protein retention in ER lumen (GO:0006621)3.62959859
40protein hydroxylation (GO:0018126)3.61835908
41polarized epithelial cell differentiation (GO:0030859)3.59063717
42dermatan sulfate biosynthetic process (GO:0030208)3.58751237
43substrate-dependent cell migration (GO:0006929)3.58060860
44stress fiber assembly (GO:0043149)3.58059402
45positive regulation of epithelial to mesenchymal transition (GO:0010718)3.55991022
46blood vessel maturation (GO:0001955)3.55865292
47regulation of extracellular matrix disassembly (GO:0010715)3.54238738
48COPI coating of Golgi vesicle (GO:0048205)3.52626896
49Golgi transport vesicle coating (GO:0048200)3.52626896
50kidney mesenchyme development (GO:0072074)3.52037358
51craniofacial suture morphogenesis (GO:0097094)3.48208378
52cell proliferation involved in metanephros development (GO:0072203)3.47359027
53wound healing, spreading of epidermal cells (GO:0035313)3.44136220
54venous blood vessel morphogenesis (GO:0048845)3.44003141
55positive regulation of endothelial cell apoptotic process (GO:2000353)3.41827081
56regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.39139595
57hyaluronan catabolic process (GO:0030214)3.39064644
58negative regulation of cartilage development (GO:0061037)3.38125793
59embryonic skeletal joint morphogenesis (GO:0060272)3.36254719
60G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.36024385
61mesenchymal-epithelial cell signaling (GO:0060638)3.34823361
62glomerular basement membrane development (GO:0032836)3.33301298
63dermatan sulfate metabolic process (GO:0030205)3.26509727
64paraxial mesoderm development (GO:0048339)3.24763398
65negative regulation of fatty acid transport (GO:2000192)3.22288789
66tooth mineralization (GO:0034505)3.16540643
67cellular response to vitamin (GO:0071295)3.13073462
68extracellular matrix organization (GO:0030198)3.11011339
69vascular endothelial growth factor signaling pathway (GO:0038084)3.10225712
70endothelial cell morphogenesis (GO:0001886)3.10038005
71extracellular structure organization (GO:0043062)3.09886476
72extracellular matrix assembly (GO:0085029)3.09698306
73cellular response to vitamin D (GO:0071305)3.07919644
74chondroitin sulfate biosynthetic process (GO:0030206)3.07909462
75protein localization to endosome (GO:0036010)3.06588455
76negative regulation of embryonic development (GO:0045992)3.05643002
77endocardial cushion development (GO:0003197)3.04639464
78cell proliferation involved in kidney development (GO:0072111)3.03739067
79embryonic cranial skeleton morphogenesis (GO:0048701)3.03186941
80positive regulation of cartilage development (GO:0061036)3.02913362
81heparan sulfate proteoglycan biosynthetic process (GO:0015012)3.02373506
82peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.02006135
83negative regulation of leukocyte chemotaxis (GO:0002689)3.02000330
84regulation of integrin-mediated signaling pathway (GO:2001044)3.00027728
85vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.99567887
86trabecula formation (GO:0060343)2.98540323
87middle ear morphogenesis (GO:0042474)2.97622668
88retina vasculature morphogenesis in camera-type eye (GO:0061299)2.97284535
89positive regulation of fibroblast migration (GO:0010763)2.93448419
90regulation of cartilage development (GO:0061035)2.92355556
91positive regulation of osteoblast proliferation (GO:0033690)2.91663620
92regulation of establishment of planar polarity (GO:0090175)2.91199722
93Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.88955025
94epithelial cell-cell adhesion (GO:0090136)2.85244762
95mesenchymal cell proliferation (GO:0010463)2.84946110
96positive regulation of receptor recycling (GO:0001921)2.84813823
97cell adhesion mediated by integrin (GO:0033627)2.82596749
98positive regulation of stem cell differentiation (GO:2000738)2.81216662
99regulation of SMAD protein import into nucleus (GO:0060390)2.80211202
100cell-substrate junction assembly (GO:0007044)2.78515708
101apoptotic cell clearance (GO:0043277)2.78205294
102mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.78188538
103regulation of collagen metabolic process (GO:0010712)2.77956479
104negative regulation of catenin import into nucleus (GO:0035414)2.77657445
105anatomical structure regression (GO:0060033)2.77392507
106regulation of early endosome to late endosome transport (GO:2000641)2.76943583
107mesenchyme morphogenesis (GO:0072132)2.76071143
108wound healing, spreading of cells (GO:0044319)2.75936037
109regulation of chondrocyte differentiation (GO:0032330)2.74563675
110regulation of heart morphogenesis (GO:2000826)2.74429603
111chondroitin sulfate catabolic process (GO:0030207)2.74369750
112positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.74273197
113notochord development (GO:0030903)2.74123901
114cranial suture morphogenesis (GO:0060363)2.73964404
115negative regulation of nitric-oxide synthase activity (GO:0051001)2.72326398
116cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.71869515
117positive regulation of axon extension (GO:0045773)2.71702141
118endochondral ossification (GO:0001958)2.71321684
119replacement ossification (GO:0036075)2.71321684
120positive regulation of extracellular matrix organization (GO:1903055)2.71061420
121glomerular filtration (GO:0003094)2.70890505
122cell migration involved in sprouting angiogenesis (GO:0002042)2.70726212
123negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.70277101
124regulation of gastrulation (GO:0010470)2.68517988
125regulation of epithelial to mesenchymal transition (GO:0010717)2.66218786
126non-canonical Wnt signaling pathway (GO:0035567)2.65908486
127regulation of monocyte chemotaxis (GO:0090025)2.64412433
128hippo signaling (GO:0035329)2.64192421
129glial cell migration (GO:0008347)2.63591234
130establishment of apical/basal cell polarity (GO:0035089)2.62850041
131mesenchyme development (GO:0060485)2.62286422
132negative regulation of BMP signaling pathway (GO:0030514)2.62106396
133regulation of smooth muscle cell migration (GO:0014910)2.60800776
134protein trimerization (GO:0070206)2.60659744
135pattern specification involved in kidney development (GO:0061004)2.60567468
136cellular response to amino acid stimulus (GO:0071230)2.60147462
137embryo implantation (GO:0007566)2.60054443
138extracellular regulation of signal transduction (GO:1900115)2.59748312
139extracellular negative regulation of signal transduction (GO:1900116)2.59748312
140pinocytosis (GO:0006907)2.59509114
141negative regulation of homotypic cell-cell adhesion (GO:0034111)2.59096766
142substrate adhesion-dependent cell spreading (GO:0034446)2.58871668
143cortical actin cytoskeleton organization (GO:0030866)2.57102843
144sprouting angiogenesis (GO:0002040)2.52925086
145positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.52922226
146decidualization (GO:0046697)2.50704098
147response to magnesium ion (GO:0032026)2.50521705

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human6.63321580
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.12478363
3RARG_19884340_ChIP-ChIP_MEFs_Mouse5.03303470
4PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse4.30447188
5CLOCK_20551151_ChIP-Seq_293T_Human3.28225009
6* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse3.12860293
7THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.12561978
8TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human3.01755450
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.57618442
10HIF1A_21447827_ChIP-Seq_MCF-7_Human2.53797424
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.40743861
12NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.40349731
13ELK3_25401928_ChIP-Seq_HUVEC_Human2.40178642
14SMAD_19615063_ChIP-ChIP_OVARY_Human2.33073244
15WT1_19549856_ChIP-ChIP_CCG9911_Human2.32242997
16* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.28962687
17EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.14968957
18CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.13952677
19EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.10645339
20NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.06664892
21WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.05915203
22RBPJ_22232070_ChIP-Seq_NCS_Mouse2.00731324
23BRD4_25478319_ChIP-Seq_HGPS_Human1.98302594
24MYC_18555785_ChIP-Seq_MESCs_Mouse1.96576945
25TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.94283144
26CJUN_26792858_Chip-Seq_BT549_Human1.86075314
27NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.84776157
28ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.81703014
29ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.81506150
30TP53_20018659_ChIP-ChIP_R1E_Mouse1.75103881
31HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.73651328
32ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.66101953
33GATA2_21666600_ChIP-Seq_HMVEC_Human1.63344315
34TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62818151
35ZFP281_18757296_ChIP-ChIP_E14_Mouse1.61161665
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.59099056
37ESR1_21235772_ChIP-Seq_MCF-7_Human1.56036973
38SMC1_22415368_ChIP-Seq_MEFs_Mouse1.54305012
39NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.54046883
40UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.53124779
41HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.51694811
42CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.49849392
43EP300_21415370_ChIP-Seq_HL-1_Mouse1.47048447
44TP53_22127205_ChIP-Seq_IMR90_Human1.45125771
45ATF3_27146783_Chip-Seq_COLON_Human1.44974343
46DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.44652415
47MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.42871458
48MYC_19079543_ChIP-ChIP_MESCs_Mouse1.41888344
49KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.40539799
50TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40276109
51UBF1/2_26484160_Chip-Seq_HMECs_Human1.35561584
52* KDM2B_26808549_Chip-Seq_K562_Human1.35270841
53SMC3_22415368_ChIP-Seq_MEFs_Mouse1.31178805
54SALL4_18804426_ChIP-ChIP_XEN_Mouse1.30752437
55* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.29875242
56ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.29685747
57KDM2B_26808549_Chip-Seq_DND41_Human1.29490343
58TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29445070
59PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.28881286
60RACK7_27058665_Chip-Seq_MCF-7_Human1.28482538
61ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.28210103
62SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.26247081
63SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.26247081
64POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25401723
65KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.25115985
66E2F7_22180533_ChIP-Seq_HELA_Human1.24119885
67TCF3_18692474_ChIP-Seq_MEFs_Mouse1.23959996
68KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.23599351
69SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.22648145
70KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.22045189
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.20965408
72LXR_22292898_ChIP-Seq_THP-1_Human1.20464643
73EED_16625203_ChIP-ChIP_MESCs_Mouse1.19850898
74STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.18659570
75SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.17803089
76NELFA_20434984_ChIP-Seq_ESCs_Mouse1.17714507
77NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.17698037
78TP53_23651856_ChIP-Seq_MEFs_Mouse1.17654950
79SA1_22415368_ChIP-Seq_MEFs_Mouse1.17648847
80TP63_19390658_ChIP-ChIP_HaCaT_Human1.17589821
81VDR_21846776_ChIP-Seq_THP-1_Human1.17583604
82* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16272154
83JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15996018
84NANOG_16153702_ChIP-ChIP_HESCs_Human1.15382636
85ELK1_22589737_ChIP-Seq_MCF10A_Human1.14404457
86AR_21909140_ChIP-Seq_LNCAP_Human1.13745123
87CTCF_27219007_Chip-Seq_ERYTHROID_Human1.13268827
88FOXM1_23109430_ChIP-Seq_U2OS_Human1.13092415
89TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.12653247
90EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.11995155
91PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.11485929
92P63_26484246_Chip-Seq_KERATINOCYTES_Human1.10988140
93KDM2B_26808549_Chip-Seq_SUP-B15_Human1.10964210
94VDR_24763502_ChIP-Seq_THP-1_Human1.09242602
95ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.08603848
96SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.08438757
97STAT3_1855785_ChIP-Seq_MESCs_Mouse1.08425649
98* TBX20_22328084_ChIP-Seq_HEART_Mouse1.07307549
99* TBX20_22080862_ChIP-Seq_HEART_Mouse1.07307549
100SA1_27219007_Chip-Seq_ERYTHROID_Human1.06483850
101ISL1_27105846_Chip-Seq_CPCs_Mouse1.05581152
102* KDM2B_26808549_Chip-Seq_JURKAT_Human1.05521447
103DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.05310663
104ESR2_21235772_ChIP-Seq_MCF-7_Human1.05050756
105* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04395694
106MYB_21317192_ChIP-Seq_ERMYB_Mouse1.04276595
107EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03894280
108XRN2_22483619_ChIP-Seq_HELA_Human1.03114435
109NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02443282
110CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.02251639
111SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.01765682
112SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00937317
113DNAJC2_21179169_ChIP-ChIP_NT2_Human1.00866630
114ZFX_18555785_ChIP-Seq_MESCs_Mouse1.00852426
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.00699186
116KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.00699186
117KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.00699186
118SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00690246
119BRD4_27068464_Chip-Seq_AML-cells_Mouse1.00644040
120Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.00409248
121CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.00092822
122ZFP281_27345836_Chip-Seq_ESCs_Mouse0.98976041
123EZH2_18974828_ChIP-Seq_MESCs_Mouse0.98376994
124RNF2_18974828_ChIP-Seq_MESCs_Mouse0.98376994
125PPAR_26484153_Chip-Seq_NCI-H1993_Human0.97725670
126* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.97493400
127SOX9_24532713_ChIP-Seq_HFSC_Mouse0.97458974
128FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.97310081
129GATA4_21415370_ChIP-Seq_HL-1_Mouse0.96549978
130JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96514182
131STAT6_21828071_ChIP-Seq_BEAS2B_Human0.95934414
132TET1_21490601_ChIP-Seq_MESCs_Mouse0.95766978
133PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95133945
134TET1_21451524_ChIP-Seq_MESCs_Mouse0.94765229
135* TCF7_22412390_ChIP-Seq_EML_Mouse0.94636558
136MYC_19030024_ChIP-ChIP_MESCs_Mouse0.94065877
137MYC_22102868_ChIP-Seq_BL_Human0.93947051
138MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.93816572
139EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.93279926
140* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.93184495
141RXR_22158963_ChIP-Seq_LIVER_Mouse0.92226441
142FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.91902968

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen7.69933089
2MP0005503_abnormal_tendon_morphology5.67645891
3MP0005275_abnormal_skin_tensile4.92465240
4MP0003705_abnormal_hypodermis_morpholog3.65470187
5MP0003279_aneurysm3.58511533
6MP0004272_abnormal_basement_membrane3.29004546
7MP0006054_spinal_hemorrhage3.14554862
8MP0001958_emphysema2.83466017
9MP0009384_cardiac_valve_regurgitation2.38014708
10MP0010030_abnormal_orbit_morphology2.34874226
11MP0005508_abnormal_skeleton_morphology2.33829657
12MP0005623_abnormal_meninges_morphology2.23667051
13MP0005257_abnormal_intraocular_pressure2.00176331
14MP0009250_abnormal_appendicular_skeleto1.94403878
15MP0003385_abnormal_body_wall1.94394352
16MP0010368_abnormal_lymphatic_system1.77805481
17MP0001542_abnormal_bone_strength1.76612958
18MP0002060_abnormal_skin_morphology1.74684989
19MP0005023_abnormal_wound_healing1.72397925
20MP0002108_abnormal_muscle_morphology1.72206266
21MP0003566_abnormal_cell_adhesion1.71509104
22MP0002282_abnormal_trachea_morphology1.70844980
23MP0004134_abnormal_chest_morphology1.62490840
24MP0005058_abnormal_lysosome_morphology1.61616233
25MP0003942_abnormal_urinary_system1.61423046
26MP0004858_abnormal_nervous_system1.58605455
27MP0003950_abnormal_plasma_membrane1.56410828
28MP0003283_abnormal_digestive_organ1.51942457
29MP0002896_abnormal_bone_mineralization1.48709606
30MP0001243_abnormal_dermal_layer1.47310952
31MP0002933_joint_inflammation1.46255709
32MP0009053_abnormal_anal_canal1.43290436
33MP0003122_maternal_imprinting1.42341654
34MP0000163_abnormal_cartilage_morphology1.41917300
35MP0002932_abnormal_joint_morphology1.41808507
36MP0002295_abnormal_pulmonary_circulatio1.40986550
37MP0000534_abnormal_ureter_morphology1.38758969
38MP0009840_abnormal_foam_cell1.38567617
39MP0002115_abnormal_skeleton_extremities1.37808296
40MP0000767_abnormal_smooth_muscle1.35877968
41MP0005390_skeleton_phenotype1.32356912
42MP0000049_abnormal_middle_ear1.30900691
43MP0003123_paternal_imprinting1.30765540
44MP0005595_abnormal_vascular_smooth1.30513659
45MP0000013_abnormal_adipose_tissue1.27601295
46MP0002254_reproductive_system_inflammat1.25482186
47MP0000733_abnormal_muscle_development1.24040170
48MP0002249_abnormal_larynx_morphology1.23325206
49MP0003115_abnormal_respiratory_system1.23026826
50MP0001879_abnormal_lymphatic_vessel1.22908971
51MP0000751_myopathy1.21512571
52MP0000428_abnormal_craniofacial_morphol1.20810145
53MP0002113_abnormal_skeleton_development1.20479635
54MP0010352_gastrointestinal_tract_polyps1.19200289
55MP0003300_gastrointestinal_ulcer1.16338244
56MP0005164_abnormal_response_to1.13967050
57MP0003191_abnormal_cellular_cholesterol1.13033749
58MP0003091_abnormal_cell_migration1.11552273
59MP0003448_altered_tumor_morphology1.11521199
60MP0002109_abnormal_limb_morphology1.05473393
61MP0003941_abnormal_skin_development1.02788982
62MP0000537_abnormal_urethra_morphology1.01155632
63MP0003755_abnormal_palate_morphology1.00364867
64MP0004510_myositis0.99227273
65MP0001299_abnormal_eye_distance/0.98528618
66MP0000343_altered_response_to0.95581727
67MP0002089_abnormal_postnatal_growth/wei0.95449450
68MP0003935_abnormal_craniofacial_develop0.95300076
69MP0002116_abnormal_craniofacial_bone0.95120170
70MP0003436_decreased_susceptibility_to0.94037090
71MP0005367_renal/urinary_system_phenotyp0.91132970
72MP0000516_abnormal_urinary_system0.91132970
73MP0002111_abnormal_tail_morphology0.91123306
74MP0005076_abnormal_cell_differentiation0.90172137
75MP0006082_CNS_inflammation0.89713148
76MP0000762_abnormal_tongue_morphology0.88449045
77MP0002128_abnormal_blood_circulation0.88397260
78MP0000750_abnormal_muscle_regeneration0.87483922
79MP0000432_abnormal_head_morphology0.87446684
80MP0003937_abnormal_limbs/digits/tail_de0.87098060
81MP0009780_abnormal_chondrocyte_physiolo0.86682031
82MP0000858_altered_metastatic_potential0.86289140
83MP0001348_abnormal_lacrimal_gland0.84850084
84MP0004883_abnormal_blood_vessel0.84587851
85MP0004084_abnormal_cardiac_muscle0.83646438
86MP0001614_abnormal_blood_vessel0.83617074
87MP0003795_abnormal_bone_structure0.83506875
88MP0005171_absent_coat_pigmentation0.82695741
89MP0002114_abnormal_axial_skeleton0.82088483
90MP0002998_abnormal_bone_remodeling0.81991996
91MP0005165_increased_susceptibility_to0.81741552
92MP0002233_abnormal_nose_morphology0.80644161
93MP0001915_intracranial_hemorrhage0.80588882
94MP0003828_pulmonary_edema0.79462809
95MP0004197_abnormal_fetal_growth/weight/0.78872366
96MP0003172_abnormal_lysosome_physiology0.78775037
97MP0003567_abnormal_fetal_cardiomyocyte0.78708949
98MP0001175_abnormal_lung_morphology0.78375752
99MP0002925_abnormal_cardiovascular_devel0.77166792
100MP0000003_abnormal_adipose_tissue0.76848720
101MP0002938_white_spotting0.75929039
102MP0001533_abnormal_skeleton_physiology0.73358208
103MP0000749_muscle_degeneration0.73293223
104MP0005388_respiratory_system_phenotype0.69860882
105MP0002133_abnormal_respiratory_system0.69860882
106MP0002697_abnormal_eye_size0.68914691
107MP0008260_abnormal_autophagy0.67630062
108MP0004808_abnormal_hematopoietic_stem0.67462397
109MP0002168_other_aberrant_phenotype0.66898245
110MP0008007_abnormal_cellular_replicative0.65778615
111MP0001270_distended_abdomen0.65634117
112MP0000759_abnormal_skeletal_muscle0.65494326
113MP0002877_abnormal_melanocyte_morpholog0.65082708
114MP0005369_muscle_phenotype0.64112813
115MP0003119_abnormal_digestive_system0.63127238
116MP0006138_congestive_heart_failure0.62745749
117MP0000266_abnormal_heart_morphology0.62288536
118MP0000249_abnormal_blood_vessel0.61827714
119MP0005193_abnormal_anterior_eye0.59864866
120MP0003075_altered_response_to0.59813565
121MP0000462_abnormal_digestive_system0.59535275
122MP0003121_genomic_imprinting0.58373575
123MP0004233_abnormal_muscle_weight0.57528826
124MP0003724_increased_susceptibility_to0.57420566
125MP0005197_abnormal_uvea_morphology0.57158469
126MP0004087_abnormal_muscle_fiber0.56887936
127MP0001849_ear_inflammation0.56863587
128MP0010630_abnormal_cardiac_muscle0.56645420
129MP0009278_abnormal_bone_marrow0.56573854
130MP0000604_amyloidosis0.56517112
131MP0005360_urolithiasis0.56350995
132MP0010386_abnormal_urinary_bladder0.53295303
133MP0000747_muscle_weakness0.53025128
134MP0000538_abnormal_urinary_bladder0.46092395

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)8.56908795
2Premature rupture of membranes (HP:0001788)7.58391635
3Ankle contracture (HP:0006466)4.78717765
4Aortic dissection (HP:0002647)4.72639811
5Soft skin (HP:0000977)4.59511782
6Abnormality of dentin (HP:0010299)4.43504744
7Shallow orbits (HP:0000586)4.42459355
8Bladder diverticulum (HP:0000015)4.16206925
9Neonatal short-limb short stature (HP:0008921)4.14825496
10Atrophic scars (HP:0001075)4.14677977
11Broad metatarsal (HP:0001783)4.08404672
12Peritonitis (HP:0002586)4.05288635
13Biconcave vertebral bodies (HP:0004586)3.87029769
14Cervical subluxation (HP:0003308)3.78810051
15Aortic aneurysm (HP:0004942)3.68333638
16Vertebral compression fractures (HP:0002953)3.61949435
17Fragile skin (HP:0001030)3.60565140
18Cerebral aneurysm (HP:0004944)3.58848311
19Wormian bones (HP:0002645)3.51271040
20Type 1 muscle fiber predominance (HP:0003803)3.47608546
21Blue sclerae (HP:0000592)3.44813003
22Follicular hyperkeratosis (HP:0007502)3.44419854
23Dilatation of the ascending aorta (HP:0005111)3.38805963
24Genu recurvatum (HP:0002816)3.32999233
25Spinal rigidity (HP:0003306)3.16200069
26Mitral valve prolapse (HP:0001634)3.03687809
27Bowel diverticulosis (HP:0005222)2.88288894
28Abnormality of the acetabulum (HP:0003170)2.82698817
29Wrist flexion contracture (HP:0001239)2.66266436
30Mesomelia (HP:0003027)2.65460225
31Abnormal delivery (HP:0001787)2.61135673
32Slender build (HP:0001533)2.60876300
33Nonimmune hydrops fetalis (HP:0001790)2.59748468
34Mild short stature (HP:0003502)2.58559696
35Increased connective tissue (HP:0009025)2.58300560
36Hypoventilation (HP:0002791)2.56126672
37Hyperextensible skin (HP:0000974)2.55369673
38Osteoarthritis (HP:0002758)2.53532349
39Breech presentation (HP:0001623)2.52634253
40Joint laxity (HP:0001388)2.50019074
41Round ear (HP:0100830)2.47822688
42Vascular tortuosity (HP:0004948)2.46295876
43Aortic valve stenosis (HP:0001650)2.44177622
44Overgrowth (HP:0001548)2.43968934
45Wide anterior fontanel (HP:0000260)2.41869591
46Achilles tendon contracture (HP:0001771)2.40683702
47Ectopia lentis (HP:0001083)2.37996303
48Deviation of the hallux (HP:0010051)2.36015699
49Disproportionate tall stature (HP:0001519)2.35831174
50Coxa vara (HP:0002812)2.35117299
51Mildly elevated creatine phosphokinase (HP:0008180)2.32386697
52Platyspondyly (HP:0000926)2.31837974
53Elbow flexion contracture (HP:0002987)2.31412824
54Ulnar bowing (HP:0003031)2.28768118
55Hallux valgus (HP:0001822)2.27743900
56Osteolytic defects of the phalanges of the hand (HP:0009771)2.26148398
57Osteolytic defects of the hand bones (HP:0009699)2.26148398
58Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.21803156
59Short 4th metacarpal (HP:0010044)2.21803156
60Broad long bones (HP:0005622)2.21058934
61Increased variability in muscle fiber diameter (HP:0003557)2.17782612
62Epiphyseal dysplasia (HP:0002656)2.17586461
63Broad ribs (HP:0000885)2.14513219
64Mitral stenosis (HP:0001718)2.13875360
65Abnormality of the Achilles tendon (HP:0005109)2.12452328
66Ovoid vertebral bodies (HP:0003300)2.10182425
67Aneurysm (HP:0002617)2.09942714
68Abnormality of the peritoneum (HP:0002585)2.09914915
69Arterial tortuosity (HP:0005116)2.08791991
70Cupped ribs (HP:0000887)2.07620885
71Beaking of vertebral bodies (HP:0004568)2.06693585
72Upper limb amyotrophy (HP:0009129)2.06188144
73Distal upper limb amyotrophy (HP:0007149)2.06188144
74Morphological abnormality of the middle ear (HP:0008609)2.05126152
75Hypoplastic ischia (HP:0003175)2.04682620
76Camptodactyly of toe (HP:0001836)2.04481763
77Infantile muscular hypotonia (HP:0008947)2.04371773
78Radial bowing (HP:0002986)2.01935027
79Mitral regurgitation (HP:0001653)2.00489107
80Spondylolisthesis (HP:0003302)2.00341213
81Ulnar deviation of the wrist (HP:0003049)2.00264807
82Decreased skull ossification (HP:0004331)1.99844449
83Femoral bowing (HP:0002980)1.99041576
84Thin bony cortex (HP:0002753)1.97923216
85Renal duplication (HP:0000075)1.97748620
86Abnormality of skeletal muscle fiber size (HP:0012084)1.94767214
87Slender long bone (HP:0003100)1.94061482
88Hip contracture (HP:0003273)1.93696577
89Premature skin wrinkling (HP:0100678)1.93059441
90Redundant skin (HP:0001582)1.92051516
91Bowed forearm bones (HP:0003956)1.89488442
92Bowing of the arm (HP:0006488)1.89488442
93Emphysema (HP:0002097)1.89228259
94Protruding ear (HP:0000411)1.87208945
95Inguinal hernia (HP:0000023)1.86624535
96Limb-girdle muscle weakness (HP:0003325)1.85316931
97Venous abnormality (HP:0002624)1.85297202
98Dysostosis multiplex (HP:0000943)1.85092523
99Joint stiffness (HP:0001387)1.84954243
100Abnormality of the calcaneus (HP:0008364)1.84735580
101Abnormality of the 4th metacarpal (HP:0010012)1.84611944
102Bell-shaped thorax (HP:0001591)1.84559310
103Knee flexion contracture (HP:0006380)1.84230117
104Osteopenia (HP:0000938)1.84135202
105Abnormality of skull ossification (HP:0002703)1.83492039
106Abnormality of mucopolysaccharide metabolism (HP:0011020)1.83124633
107Abnormality of polysaccharide metabolism (HP:0011012)1.83124633
108Abnormality of glycosaminoglycan metabolism (HP:0004371)1.83124633
109Tibial bowing (HP:0002982)1.82935968
110Mucopolysacchariduria (HP:0008155)1.81984375
111Urinary glycosaminoglycan excretion (HP:0003541)1.81984375
112Delayed closure of the anterior fontanelle (HP:0001476)1.79116281
113Short nail (HP:0001799)1.79012974
114Aortic regurgitation (HP:0001659)1.78684578
115Metaphyseal cupping (HP:0003021)1.78542526
116Abnormality of the ischium (HP:0003174)1.78243022
117Broad phalanx (HP:0006009)1.77801272
118Generalized amyotrophy (HP:0003700)1.77675950
119Long toe (HP:0010511)1.77208503
120Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.75434974
121Delayed cranial suture closure (HP:0000270)1.73898879
122Syringomyelia (HP:0003396)1.72512427
123Spinal cord lesions (HP:0100561)1.72512427
124Deformed tarsal bones (HP:0008119)1.70470726
125Asymmetry of the thorax (HP:0001555)1.69889344
126Venous insufficiency (HP:0005293)1.69761350
127Selective tooth agenesis (HP:0001592)1.69718758
128Thoracolumbar scoliosis (HP:0002944)1.69572810
129Hand muscle atrophy (HP:0009130)1.68755259
130Natal tooth (HP:0000695)1.68425702
131Coronal craniosynostosis (HP:0004440)1.68297840
132Abnormality of glycosphingolipid metabolism (HP:0004343)1.67803324

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR25.06240600
2TRIB34.19408334
3PDGFRA3.27278039
4PKN23.24104243
5TTN3.08573785
6LATS22.90569399
7ERN12.76611695
8EPHB22.71251683
9LATS12.28714619
10MYLK2.17737847
11SIK11.97153911
12TGFBR21.91917310
13PAK21.89819723
14KDR1.88722937
15TGFBR11.83535692
16PAK41.81325406
17RPS6KA41.65946266
18MAP3K101.65549533
19LRRK21.64887763
20NME21.62550300
21EPHA31.62439239
22NTRK11.60492545
23RIPK11.59106605
24PRPF4B1.57514731
25FLT31.54966962
26EEF2K1.54042096
27ILK1.47169154
28PTK21.46467451
29PTK61.41232053
30MAP3K31.39712569
31STK38L1.38966269
32STK381.35700220
33PIM21.31902363
34MAP3K61.29889411
35TIE11.28837672
36TESK11.28546854
37FGFR11.19212183
38TYK21.16626932
39IRAK31.11092198
40STK31.08201609
41BMX1.06970802
42FER1.05864402
43MAPK71.04956352
44MAP2K31.04343496
45TRPM71.02964979
46DMPK0.99719385
47PIK3CG0.96698462
48ROCK10.96655247
49PIK3CA0.96200368
50PTK2B0.96081513
51MTOR0.94682669
52ICK0.94400904
53MET0.94072879
54RPS6KA20.93952528
55MAP3K110.93553595
56LIMK10.92797793
57ZAP700.92743904
58SMG10.90887134
59TBK10.90763288
60NEK90.90424025
61PAK30.88564896
62ARAF0.86961050
63PDGFRB0.84831556
64BUB10.82354765
65PAK60.81008895
66PRKD30.78699954
67KIT0.78303351
68DAPK30.75543758
69LMTK20.74275075
70CDK70.74063693
71PAK10.73452920
72PRKG20.73433534
73MARK20.72439620
74AKT30.68736892
75MOS0.68414330
76JAK10.65823834
77MAP3K80.64659242
78GRK70.64617856
79KSR20.61086686
80PASK0.60493338
81ERBB30.60460750
82CDC42BPA0.60263746
83NEK20.58857959
84TAOK10.58250638
85CDK80.57847984
86PDPK10.56701458
87MAP3K10.55959910
88PRKD20.55819260
89MAPKAPK30.55390291
90MKNK10.55240178
91MAP3K70.54910921
92RPS6KB20.54415952
93TESK20.54052107
94SCYL20.52097410
95MAP3K130.51721491
96MAP2K10.47918815
97DYRK30.47386193
98GRK50.47069527
99ROCK20.47008745
100GSK3A0.46369895
101TAOK20.43396139
102STK100.40657750
103PRKD10.40613734
104CLK10.40095810
105FGFR40.39832446
106INSR0.39388846
107STK240.36707759
108MAPKAPK20.36689033
109EPHB10.36455425
110BLK0.36122884
111JAK30.35323408
112ERBB40.35072988
113AURKB0.34932604
114CSK0.34712800
115DYRK1B0.34586658
116BRAF0.34454741
117MAPK40.34393970
118BRSK20.33945110
119RET0.33272990
120ZAK0.32781791
121ERBB20.32698708
122GRK60.31785579
123ADRBK10.31653679
124MAPK10.30862459
125HIPK20.30759483
126PLK30.30338585
127RPS6KC10.30250687
128RPS6KL10.30250687
129WNK10.30222336
130SRC0.29884453
131RPS6KA60.29558697
132ABL20.29467211
133WEE10.29081831
134CDK40.28587974
135ACVR1B0.28198615
136OBSCN0.28089602
137PRKCI0.27328230
138CDK60.27289692

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.85942534
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.65300088
3Protein digestion and absorption_Homo sapiens_hsa049743.23475606
4Focal adhesion_Homo sapiens_hsa045103.13276779
5Basal cell carcinoma_Homo sapiens_hsa052172.53565454
6TGF-beta signaling pathway_Homo sapiens_hsa043502.22577353
7Proteoglycans in cancer_Homo sapiens_hsa052052.16816690
8Hedgehog signaling pathway_Homo sapiens_hsa043402.11243362
9AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.06687540
10Hippo signaling pathway_Homo sapiens_hsa043902.04897837
11Bladder cancer_Homo sapiens_hsa052191.99008319
12Malaria_Homo sapiens_hsa051441.97515516
13Amoebiasis_Homo sapiens_hsa051461.89888399
14Small cell lung cancer_Homo sapiens_hsa052221.88407003
15Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.83112810
16PI3K-Akt signaling pathway_Homo sapiens_hsa041511.81922631
17Adherens junction_Homo sapiens_hsa045201.74848825
18Dilated cardiomyopathy_Homo sapiens_hsa054141.71716811
19Ribosome_Homo sapiens_hsa030101.70952393
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.68613370
21Lysosome_Homo sapiens_hsa041421.67387469
22Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.66967359
23Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.59470412
24MicroRNAs in cancer_Homo sapiens_hsa052061.59438897
25Prion diseases_Homo sapiens_hsa050201.52794717
26p53 signaling pathway_Homo sapiens_hsa041151.49686107
27Complement and coagulation cascades_Homo sapiens_hsa046101.34215112
28Cell cycle_Homo sapiens_hsa041101.32504719
29Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.31311533
30Chronic myeloid leukemia_Homo sapiens_hsa052201.31018880
31HTLV-I infection_Homo sapiens_hsa051661.27961885
32Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.26591698
33Pertussis_Homo sapiens_hsa051331.25960961
34Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.24966598
35Osteoclast differentiation_Homo sapiens_hsa043801.22706360
36Pathways in cancer_Homo sapiens_hsa052001.22348228
37Wnt signaling pathway_Homo sapiens_hsa043101.19543838
38N-Glycan biosynthesis_Homo sapiens_hsa005101.15581374
39Melanoma_Homo sapiens_hsa052181.14664078
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.11950855
41Vibrio cholerae infection_Homo sapiens_hsa051101.05770419
42Notch signaling pathway_Homo sapiens_hsa043301.04429684
43Central carbon metabolism in cancer_Homo sapiens_hsa052301.03203604
44Leukocyte transendothelial migration_Homo sapiens_hsa046700.98719739
45Phospholipase D signaling pathway_Homo sapiens_hsa040720.97958426
46Regulation of actin cytoskeleton_Homo sapiens_hsa048100.96903462
47Platelet activation_Homo sapiens_hsa046110.95013829
48Viral myocarditis_Homo sapiens_hsa054160.94712205
49Prostate cancer_Homo sapiens_hsa052150.94570476
50Spliceosome_Homo sapiens_hsa030400.93383037
51HIF-1 signaling pathway_Homo sapiens_hsa040660.91191720
52Endocytosis_Homo sapiens_hsa041440.90144670
53Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89548445
54Protein export_Homo sapiens_hsa030600.88691316
55Glycosaminoglycan degradation_Homo sapiens_hsa005310.88408415
56Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.87858040
57Thyroid cancer_Homo sapiens_hsa052160.87119786
58DNA replication_Homo sapiens_hsa030300.86864104
59Base excision repair_Homo sapiens_hsa034100.86250533
60Salmonella infection_Homo sapiens_hsa051320.83649300
61Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82589366
62RNA transport_Homo sapiens_hsa030130.82244506
63Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.81537335
64Shigellosis_Homo sapiens_hsa051310.81535196
65Toxoplasmosis_Homo sapiens_hsa051450.80984484
66Viral carcinogenesis_Homo sapiens_hsa052030.80788161
67Tight junction_Homo sapiens_hsa045300.80673114
68Melanogenesis_Homo sapiens_hsa049160.80269822
69Pancreatic cancer_Homo sapiens_hsa052120.78965645
70Rap1 signaling pathway_Homo sapiens_hsa040150.77247061
71Galactose metabolism_Homo sapiens_hsa000520.75069971
72Staphylococcus aureus infection_Homo sapiens_hsa051500.74335095
73Toll-like receptor signaling pathway_Homo sapiens_hsa046200.74300178
74Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.74030756
75Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.73130855
76TNF signaling pathway_Homo sapiens_hsa046680.72024777
77Colorectal cancer_Homo sapiens_hsa052100.71895253
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69794960
79GnRH signaling pathway_Homo sapiens_hsa049120.69104780
80Gap junction_Homo sapiens_hsa045400.67800559
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67333452
82One carbon pool by folate_Homo sapiens_hsa006700.66042516
83Apoptosis_Homo sapiens_hsa042100.65563589
84Pentose phosphate pathway_Homo sapiens_hsa000300.64973457
85Leishmaniasis_Homo sapiens_hsa051400.63805724
86VEGF signaling pathway_Homo sapiens_hsa043700.63801757
87Sulfur metabolism_Homo sapiens_hsa009200.62245217
88Other glycan degradation_Homo sapiens_hsa005110.61162449
89Proteasome_Homo sapiens_hsa030500.60949551
90Hepatitis B_Homo sapiens_hsa051610.60837143
91Tuberculosis_Homo sapiens_hsa051520.60199430
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58990295
93Nucleotide excision repair_Homo sapiens_hsa034200.58838372
94Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57072913
95Ras signaling pathway_Homo sapiens_hsa040140.54981199
96African trypanosomiasis_Homo sapiens_hsa051430.53955370
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.53614173
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.53453539
99Glioma_Homo sapiens_hsa052140.53106391
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52453002
101Rheumatoid arthritis_Homo sapiens_hsa053230.52435670
102Hepatitis C_Homo sapiens_hsa051600.51246149
103Axon guidance_Homo sapiens_hsa043600.50949588
104Sphingolipid metabolism_Homo sapiens_hsa006000.50055481
105MAPK signaling pathway_Homo sapiens_hsa040100.47945307
106Sulfur relay system_Homo sapiens_hsa041220.47782755
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47433571
108Insulin resistance_Homo sapiens_hsa049310.46545086
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45378579
110Antigen processing and presentation_Homo sapiens_hsa046120.44413806
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43477689
112mTOR signaling pathway_Homo sapiens_hsa041500.43357140
113Influenza A_Homo sapiens_hsa051640.42545110
114Mismatch repair_Homo sapiens_hsa034300.42333485
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40860191
116Thyroid hormone synthesis_Homo sapiens_hsa049180.40047960
117Endometrial cancer_Homo sapiens_hsa052130.38863149
118Neurotrophin signaling pathway_Homo sapiens_hsa047220.38803065
119Acute myeloid leukemia_Homo sapiens_hsa052210.37704662
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36762262
121Lysine degradation_Homo sapiens_hsa003100.36446577
122Vascular smooth muscle contraction_Homo sapiens_hsa042700.35024440
123Renin-angiotensin system_Homo sapiens_hsa046140.34811218
124Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34679509
125FoxO signaling pathway_Homo sapiens_hsa040680.34549092
126Phagosome_Homo sapiens_hsa041450.33839504
127Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.33815155
128Renal cell carcinoma_Homo sapiens_hsa052110.33440708
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32967914
130Epstein-Barr virus infection_Homo sapiens_hsa051690.31928540
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31408637
132cGMP-PKG signaling pathway_Homo sapiens_hsa040220.31279008
133Legionellosis_Homo sapiens_hsa051340.30640851
134Estrogen signaling pathway_Homo sapiens_hsa049150.30390759
135RNA degradation_Homo sapiens_hsa030180.29399643
136Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.29238439

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