RCOR3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1inositol phosphate catabolic process (GO:0071545)5.80874750
2phosphorylated carbohydrate dephosphorylation (GO:0046838)5.48827251
3inositol phosphate dephosphorylation (GO:0046855)5.48827251
4establishment of protein localization to Golgi (GO:0072600)4.64839936
5protein targeting to Golgi (GO:0000042)4.50613035
6polyol catabolic process (GO:0046174)4.31675021
7retrograde transport, vesicle recycling within Golgi (GO:0000301)4.20647946
8piRNA metabolic process (GO:0034587)4.08839899
9protein localization to Golgi apparatus (GO:0034067)4.04230794
10doxorubicin metabolic process (GO:0044598)3.92524736
11daunorubicin metabolic process (GO:0044597)3.92524736
12polyketide metabolic process (GO:0030638)3.92524736
13energy homeostasis (GO:0097009)3.67910598
14phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.61075245
15interkinetic nuclear migration (GO:0022027)3.55546076
16inositol metabolic process (GO:0006020)3.54077396
17epithelial cilium movement (GO:0003351)3.47044304
18cilium or flagellum-dependent cell motility (GO:0001539)3.41364621
19acrosome reaction (GO:0007340)3.39394671
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.37891076
21neural tube formation (GO:0001841)3.37526363
22response to pheromone (GO:0019236)3.37393357
23DNA methylation involved in gamete generation (GO:0043046)3.29543709
24protein K11-linked deubiquitination (GO:0035871)3.23148726
25G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.21728240
26signal peptide processing (GO:0006465)3.15807886
27presynaptic membrane assembly (GO:0097105)3.14832142
28short-chain fatty acid metabolic process (GO:0046459)3.13903331
29negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.13339302
30definitive hemopoiesis (GO:0060216)3.12122415
31detection of calcium ion (GO:0005513)3.08287520
32cellular ketone body metabolic process (GO:0046950)3.06234483
33intra-Golgi vesicle-mediated transport (GO:0006891)2.99872847
34photoreceptor cell differentiation (GO:0046530)2.96570564
35eye photoreceptor cell differentiation (GO:0001754)2.96570564
36positive regulation of meiosis (GO:0045836)2.96116011
37intraciliary transport (GO:0042073)2.94567302
38phospholipid dephosphorylation (GO:0046839)2.93963551
39phosphatidylinositol dephosphorylation (GO:0046856)2.88675905
40ketone body metabolic process (GO:1902224)2.87650404
41sperm motility (GO:0030317)2.87491325
42negative regulation of exocytosis (GO:0045920)2.84664575
43regulation of pigment cell differentiation (GO:0050932)2.84472786
44regulation of meiosis I (GO:0060631)2.84165566
45prenylation (GO:0097354)2.83377754
46protein prenylation (GO:0018342)2.83377754
47presynaptic membrane organization (GO:0097090)2.83250340
48positive regulation of granulocyte differentiation (GO:0030854)2.79235439
49microtubule nucleation (GO:0007020)2.79049946
50regulation of hexokinase activity (GO:1903299)2.78704664
51regulation of glucokinase activity (GO:0033131)2.78704664
52cilium movement (GO:0003341)2.75524906
53axonemal dynein complex assembly (GO:0070286)2.74695813
54early endosome to late endosome transport (GO:0045022)2.73863768
55GPI anchor biosynthetic process (GO:0006506)2.73044947
56histone H3-K4 trimethylation (GO:0080182)2.72416931
57positive regulation of action potential (GO:0045760)2.70722809
58detection of light stimulus involved in sensory perception (GO:0050962)2.69612813
59detection of light stimulus involved in visual perception (GO:0050908)2.69612813
60positive regulation of meiotic cell cycle (GO:0051446)2.68072457
61pharyngeal system development (GO:0060037)2.66645950
62regulation of skeletal muscle contraction (GO:0014819)2.65824088
63axoneme assembly (GO:0035082)2.64693186
64urinary tract smooth muscle contraction (GO:0014848)2.64304984
65negative regulation of protein oligomerization (GO:0032460)2.63143773
66negative regulation of cytosolic calcium ion concentration (GO:0051481)2.61624866
67Golgi to endosome transport (GO:0006895)2.60031348
68negative regulation of osteoblast proliferation (GO:0033689)2.58996750
69positive regulation of glycolytic process (GO:0045821)2.58742983
70negative regulation of execution phase of apoptosis (GO:1900118)2.57643840
71regulation of protein glycosylation (GO:0060049)2.57277538
72positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.57136427
73mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.57136427
74dentate gyrus development (GO:0021542)2.56795545
75auditory behavior (GO:0031223)2.56483950
76nucleotide transmembrane transport (GO:1901679)2.55717353
77reflex (GO:0060004)2.55628923
78nerve growth factor signaling pathway (GO:0038180)2.54967812
79cell differentiation involved in metanephros development (GO:0072202)2.53516514
80preassembly of GPI anchor in ER membrane (GO:0016254)2.53474806
81dendritic spine morphogenesis (GO:0060997)2.53332935
82cAMP catabolic process (GO:0006198)2.52397621
83dopamine transport (GO:0015872)2.50050520
84parental behavior (GO:0060746)2.49287861
85negative regulation of transcription by competitive promoter binding (GO:0010944)2.48977089
86negative regulation of neurotransmitter secretion (GO:0046929)2.48763487
87pyrimidine ribonucleoside catabolic process (GO:0046133)2.48747332
88protein localization to cilium (GO:0061512)2.48497210
89fusion of sperm to egg plasma membrane (GO:0007342)2.46543334
90cytidine metabolic process (GO:0046087)2.45446802
91cytidine catabolic process (GO:0006216)2.45446802
92cytidine deamination (GO:0009972)2.45446802
93GPI anchor metabolic process (GO:0006505)2.45072020
94acrosome assembly (GO:0001675)2.45030883
95regulation of relaxation of muscle (GO:1901077)2.44999017
96left/right pattern formation (GO:0060972)2.43910309
97RNA destabilization (GO:0050779)2.43819628
98sperm capacitation (GO:0048240)2.42025483
99regulation of Rac protein signal transduction (GO:0035020)2.41613100
100multicellular organism reproduction (GO:0032504)2.41352757
101photoreceptor cell maintenance (GO:0045494)2.40441383
102protein-chromophore linkage (GO:0018298)2.39986113
103calcium ion import (GO:0070509)2.39077281
104peripheral nervous system neuron development (GO:0048935)2.38466017
105monoubiquitinated protein deubiquitination (GO:0035520)2.38233557
106positive regulation of dendritic spine morphogenesis (GO:0061003)2.37649220
107proline transport (GO:0015824)2.37640607
108regulation of sarcomere organization (GO:0060297)2.37299284
109nonmotile primary cilium assembly (GO:0035058)2.36464178
110negative regulation of gluconeogenesis (GO:0045721)2.35676170
111spermatid nucleus differentiation (GO:0007289)2.35661755
112ether lipid metabolic process (GO:0046485)2.35561291
113histone H2A ubiquitination (GO:0033522)2.35238550
114sympathetic nervous system development (GO:0048485)2.34130393
115facial nerve structural organization (GO:0021612)2.33275473
116regulation of cell communication by electrical coupling (GO:0010649)2.32815848
117glycosphingolipid biosynthetic process (GO:0006688)2.32453355
118positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.31804737
119regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.31804737
120negative regulation of dendrite development (GO:2000171)2.31611156
121purinergic nucleotide receptor signaling pathway (GO:0035590)2.31550245
122nucleus localization (GO:0051647)2.30676106
123regulation of female gonad development (GO:2000194)2.30546052
124postsynaptic membrane organization (GO:0001941)2.30240287
125cilium assembly (GO:0042384)2.30040004
126gene silencing by RNA (GO:0031047)2.29645187
127nucleoside diphosphate catabolic process (GO:0009134)2.28915460
128regulation of Golgi to plasma membrane protein transport (GO:0042996)2.28766481
129negative regulation of JUN kinase activity (GO:0043508)2.28012105
130regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.27700743
131mesenchymal cell differentiation involved in kidney development (GO:0072161)2.27206108
132mesenchymal cell differentiation involved in renal system development (GO:2001012)2.27206108
133response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.26733266
134microtubule anchoring (GO:0034453)2.26246473
135regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.25343626
136positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.25343626
137membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.24698763
138ganglion development (GO:0061548)2.24654717
139righting reflex (GO:0060013)2.24257976
140inner ear receptor stereocilium organization (GO:0060122)2.23799301
141aminoglycoside antibiotic metabolic process (GO:0030647)2.23549524
142negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.23307069
143regulation of memory T cell differentiation (GO:0043380)2.23074014
144positive regulation of steroid hormone secretion (GO:2000833)2.22653975
145extracellular regulation of signal transduction (GO:1900115)2.22048387
146extracellular negative regulation of signal transduction (GO:1900116)2.22048387
147phosphatidylinositol phosphorylation (GO:0046854)2.21801220
148regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.21758263
149cilium organization (GO:0044782)2.21236760
150adaptation of signaling pathway (GO:0023058)2.19913865
151regulation of germinal center formation (GO:0002634)2.19893379
152positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc2.19891670
153myofibril assembly (GO:0030239)2.19788316
154negative regulation of translation, ncRNA-mediated (GO:0040033)2.19192603
155regulation of translation, ncRNA-mediated (GO:0045974)2.19192603
156negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.19192603
157retina layer formation (GO:0010842)2.18765976
158parturition (GO:0007567)2.17828775
159inner ear receptor cell differentiation (GO:0060113)2.16484581
160nitric oxide mediated signal transduction (GO:0007263)2.15736501
161response to epinephrine (GO:0071871)2.14936432
162mannosylation (GO:0097502)2.14310740
163cyclic nucleotide catabolic process (GO:0009214)2.14154126
164activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.13927080
165superoxide anion generation (GO:0042554)2.13421085
166regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.13049640
167sarcoplasmic reticulum calcium ion transport (GO:0070296)2.11934178
168cranial nerve structural organization (GO:0021604)2.11623225
169negative regulation of systemic arterial blood pressure (GO:0003085)2.10911137
170motile cilium assembly (GO:0044458)2.10755136
171developmental pigmentation (GO:0048066)2.10745795
172negative regulation of neurotransmitter transport (GO:0051589)2.10270230
173ER overload response (GO:0006983)2.08978349
174response to redox state (GO:0051775)2.08869029
175mechanoreceptor differentiation (GO:0042490)2.07452316
176heart process (GO:0003015)2.07122835
177heart contraction (GO:0060047)2.07122835
178sequestering of extracellular ligand from receptor (GO:0035581)2.07116425

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.72840956
2EZH2_22144423_ChIP-Seq_EOC_Human2.95385284
3SALL1_21062744_ChIP-ChIP_HESCs_Human2.64945033
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.56850722
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.47005074
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.37530031
7PCGF2_27294783_Chip-Seq_ESCs_Mouse2.29494149
8ZNF274_21170338_ChIP-Seq_K562_Hela2.27667609
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.23266624
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.18622244
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.04333167
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.99841001
13SUZ12_27294783_Chip-Seq_NPCs_Mouse1.89951197
14* NANOG_18555785_Chip-Seq_ESCs_Mouse1.89066933
15* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.85916710
16TAF15_26573619_Chip-Seq_HEK293_Human1.85168071
17HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.84807265
18VDR_22108803_ChIP-Seq_LS180_Human1.81846428
19PCGF2_27294783_Chip-Seq_NPCs_Mouse1.80498189
20EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.79265406
21PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.78435332
22P300_19829295_ChIP-Seq_ESCs_Human1.74703413
23NFE2_27457419_Chip-Seq_LIVER_Mouse1.73279992
24* P53_22387025_ChIP-Seq_ESCs_Mouse1.72589643
25SMAD4_21799915_ChIP-Seq_A2780_Human1.72087401
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70412413
27* E2F1_18555785_Chip-Seq_ESCs_Mouse1.68165723
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.67856504
29* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.67735215
30* EZH2_27294783_Chip-Seq_NPCs_Mouse1.64984693
31FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.60875280
32* CMYC_18555785_Chip-Seq_ESCs_Mouse1.59999618
33* STAT3_18555785_Chip-Seq_ESCs_Mouse1.59458144
34CDX2_19796622_ChIP-Seq_MESCs_Mouse1.59313752
35SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.56295984
36FUS_26573619_Chip-Seq_HEK293_Human1.55344638
37* P300_18555785_Chip-Seq_ESCs_Mouse1.54390969
38PIAS1_25552417_ChIP-Seq_VCAP_Human1.54242735
39* SOX2_18555785_Chip-Seq_ESCs_Mouse1.51399231
40PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.51097344
41* NMYC_18555785_Chip-Seq_ESCs_Mouse1.50838010
42IGF1R_20145208_ChIP-Seq_DFB_Human1.48554287
43AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.48452318
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.48233084
45* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.47952083
46JARID2_20064375_ChIP-Seq_MESCs_Mouse1.45817753
47* OCT4_18555785_Chip-Seq_ESCs_Mouse1.44566136
48MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.44029644
49CBP_20019798_ChIP-Seq_JUKART_Human1.43282716
50IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.43282716
51BCAT_22108803_ChIP-Seq_LS180_Human1.40801178
52SMAD_19615063_ChIP-ChIP_OVARY_Human1.40797717
53ER_23166858_ChIP-Seq_MCF-7_Human1.40640401
54TAL1_26923725_Chip-Seq_HPCs_Mouse1.39738524
55EZH2_27304074_Chip-Seq_ESCs_Mouse1.39572937
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.37616998
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.37194662
58SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.37031244
59SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.35891813
60OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35779266
61* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.35699007
62* PU1_27457419_Chip-Seq_LIVER_Mouse1.34613271
63* ZFX_18555785_Chip-Seq_ESCs_Mouse1.33880579
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33827171
65FLI1_21867929_ChIP-Seq_TH2_Mouse1.33133728
66EED_16625203_ChIP-ChIP_MESCs_Mouse1.33095260
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32942933
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32942933
69TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.32319693
70PRDM14_20953172_ChIP-Seq_ESCs_Human1.32266487
71* KLF4_18555785_Chip-Seq_ESCs_Mouse1.30271185
72SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.30076053
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.29842577
74* CRX_20693478_ChIP-Seq_RETINA_Mouse1.29513085
75EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.29309691
76LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.29243452
77* CTCF_18555785_Chip-Seq_ESCs_Mouse1.28973212
78TCF4_23295773_ChIP-Seq_U87_Human1.28955481
79EWS_26573619_Chip-Seq_HEK293_Human1.27664987
80STAT3_23295773_ChIP-Seq_U87_Human1.26728314
81SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26597908
82SOX2_21211035_ChIP-Seq_LN229_Gbm1.26042467
83AR_21572438_ChIP-Seq_LNCaP_Human1.25817741
84SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.25561918
85CTBP2_25329375_ChIP-Seq_LNCAP_Human1.24646206
86RNF2_27304074_Chip-Seq_NSC_Mouse1.24620602
87* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.24524247
88SOX2_19829295_ChIP-Seq_ESCs_Human1.24204455
89NANOG_19829295_ChIP-Seq_ESCs_Human1.24204455
90* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.23122873
91GATA1_22025678_ChIP-Seq_K562_Human1.22386139
92TP53_18474530_ChIP-ChIP_U2OS_Human1.22063315
93RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21112774
94* SMAD1_18555785_Chip-Seq_ESCs_Mouse1.20218762
95* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.20151745
96MTF2_20144788_ChIP-Seq_MESCs_Mouse1.20106102
97* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20079727
98ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18950127
99KDM2B_26808549_Chip-Seq_REH_Human1.18824444
100BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.18768851
101ARNT_22903824_ChIP-Seq_MCF-7_Human1.18391880
102* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.16458647
103AR_25329375_ChIP-Seq_VCAP_Human1.16212221
104WT1_19549856_ChIP-ChIP_CCG9911_Human1.14594542
105IRF8_22096565_ChIP-ChIP_GC-B_Human1.13589912
106* RUNX2_22187159_ChIP-Seq_PCA_Human1.12911022
107UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12882748
108CDX2_22108803_ChIP-Seq_LS180_Human1.12867828
109TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.12672967
110RBPJ_22232070_ChIP-Seq_NCS_Mouse1.12414217
111CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12083854
112CTBP1_25329375_ChIP-Seq_LNCAP_Human1.12036303
113RNF2_27304074_Chip-Seq_ESCs_Mouse1.11764592
114* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.11282701
115SMAD4_21741376_ChIP-Seq_EPCs_Human1.11026222
116* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10603898
117SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10333474
118AHR_22903824_ChIP-Seq_MCF-7_Human1.10057170
119EZH2_27294783_Chip-Seq_ESCs_Mouse1.09854726
120TCF4_22108803_ChIP-Seq_LS180_Human1.09818077
121SUZ12_27294783_Chip-Seq_ESCs_Mouse1.08794585
122* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.08235208
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07566231
124NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.06527505
125NRF2_20460467_ChIP-Seq_MEFs_Mouse1.06527505
126ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05807182
127KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05308158
128FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03797225
129LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01493331
130EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01033796
131* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99289888
132TCF4_18268006_ChIP-ChIP_LS174T_Human0.99221349

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001188_hyperpigmentation3.22729566
2MP0005410_abnormal_fertilization2.85047980
3MP0005409_darkened_coat_color2.76773058
4MP0003183_abnormal_peptide_metabolism2.71826467
5MP0005646_abnormal_pituitary_gland2.68037752
6MP0005379_endocrine/exocrine_gland_phen2.64707576
7MP0005171_absent_coat_pigmentation2.60879706
8MP0002822_catalepsy2.60516681
9MP0002837_dystrophic_cardiac_calcinosis2.58678213
10MP0002638_abnormal_pupillary_reflex2.46003652
11MP0010386_abnormal_urinary_bladder2.29568467
12MP0001986_abnormal_taste_sensitivity2.25303589
13MP0002928_abnormal_bile_duct2.22381001
14MP0003646_muscle_fatigue2.19992478
15MP0005083_abnormal_biliary_tract2.18006548
16MP0003011_delayed_dark_adaptation2.13971136
17MP0008057_abnormal_DNA_replication2.12728250
18MP0002009_preneoplasia2.11999677
19MP0000015_abnormal_ear_pigmentation2.06102469
20MP0005645_abnormal_hypothalamus_physiol2.00857111
21MP0005174_abnormal_tail_pigmentation1.99092642
22MP0003195_calcinosis1.96537250
23MP0008995_early_reproductive_senescence1.91444670
24MP0003136_yellow_coat_color1.76548633
25MP0000566_synostosis1.75946544
26MP0000372_irregular_coat_pigmentation1.72974720
27MP0001502_abnormal_circadian_rhythm1.66683588
28MP0001984_abnormal_olfaction1.64923090
29MP0004859_abnormal_synaptic_plasticity1.64870181
30MP0002938_white_spotting1.64205047
31MP0002163_abnormal_gland_morphology1.62297932
32MP0003724_increased_susceptibility_to1.61324669
33MP0002102_abnormal_ear_morphology1.58715871
34MP0004381_abnormal_hair_follicle1.58409069
35MP0000749_muscle_degeneration1.57881631
36MP0006292_abnormal_olfactory_placode1.56261269
37MP0005551_abnormal_eye_electrophysiolog1.50949203
38MP0000427_abnormal_hair_cycle1.50642877
39MP0002735_abnormal_chemical_nociception1.47726737
40MP0004084_abnormal_cardiac_muscle1.45210331
41MP0003121_genomic_imprinting1.44223008
42MP0009697_abnormal_copulation1.43068097
43MP0004130_abnormal_muscle_cell1.40663230
44MP0006072_abnormal_retinal_apoptosis1.40638048
45MP0002876_abnormal_thyroid_physiology1.39807216
46MP0005075_abnormal_melanosome_morpholog1.38839104
47MP0004215_abnormal_myocardial_fiber1.38471412
48MP0003950_abnormal_plasma_membrane1.37213801
49MP0003656_abnormal_erythrocyte_physiolo1.32460531
50MP0005386_behavior/neurological_phenoty1.28210142
51MP0004924_abnormal_behavior1.28210142
52MP0003045_fibrosis1.28006438
53MP0003943_abnormal_hepatobiliary_system1.26576632
54MP0004147_increased_porphyrin_level1.24748334
55MP0005503_abnormal_tendon_morphology1.23513691
56MP0005253_abnormal_eye_physiology1.22531256
57MP0004742_abnormal_vestibular_system1.21791454
58MP0005220_abnormal_exocrine_pancreas1.21423604
59MP0003635_abnormal_synaptic_transmissio1.20681823
60MP0001764_abnormal_homeostasis1.19525195
61MP0002095_abnormal_skin_pigmentation1.19198602
62MP0002272_abnormal_nervous_system1.18815130
63MP0001486_abnormal_startle_reflex1.18236692
64MP0003880_abnormal_central_pattern1.17817879
65MP0000383_abnormal_hair_follicle1.17431579
66MP0004885_abnormal_endolymph1.13877637
67MP0001346_abnormal_lacrimal_gland1.12101156
68MP0002106_abnormal_muscle_physiology1.11093705
69MP0002693_abnormal_pancreas_physiology1.10933890
70MP0000631_abnormal_neuroendocrine_gland1.06789474
71MP0002063_abnormal_learning/memory/cond1.06012109
72MP0009780_abnormal_chondrocyte_physiolo1.04335772
73MP0008877_abnormal_DNA_methylation1.04313061
74MP0006276_abnormal_autonomic_nervous1.02022608
75MP0002877_abnormal_melanocyte_morpholog1.01922291
76MP0000013_abnormal_adipose_tissue1.01776313
77MP0004043_abnormal_pH_regulation0.98895429
78MP0000516_abnormal_urinary_system0.96167114
79MP0005367_renal/urinary_system_phenotyp0.96167114
80MP0004145_abnormal_muscle_electrophysio0.94797069
81MP0001501_abnormal_sleep_pattern0.93876749
82MP0002572_abnormal_emotion/affect_behav0.93769979
83MP0002909_abnormal_adrenal_gland0.93768825
84MP0004134_abnormal_chest_morphology0.93490576
85MP0008775_abnormal_heart_ventricle0.92202606
86MP0002277_abnormal_respiratory_mucosa0.92117460
87MP0002064_seizures0.91804754
88MP0005423_abnormal_somatic_nervous0.91794390
89MP0004085_abnormal_heartbeat0.91429620
90MP0002067_abnormal_sensory_capabilities0.91331234
91MP0005369_muscle_phenotype0.91082242
92MP0000681_abnormal_thyroid_gland0.90263104
93MP0003890_abnormal_embryonic-extraembry0.90220650
94MP0005085_abnormal_gallbladder_physiolo0.89445489
95MP0001485_abnormal_pinna_reflex0.89443237
96MP0000569_abnormal_digit_pigmentation0.88939156
97MP0003787_abnormal_imprinting0.88228110
98MP0002078_abnormal_glucose_homeostasis0.86812140
99MP0000751_myopathy0.86460319
100MP0002177_abnormal_outer_ear0.83633574
101MP0000026_abnormal_inner_ear0.83585975
102MP0000678_abnormal_parathyroid_gland0.83563305
103MP0005535_abnormal_body_temperature0.82917552
104MP0002127_abnormal_cardiovascular_syste0.82846848
105MP0000538_abnormal_urinary_bladder0.82434649
106MP0001929_abnormal_gametogenesis0.82139893
107MP0004142_abnormal_muscle_tone0.82062772
108MP0009250_abnormal_appendicular_skeleto0.81564837
109MP0003122_maternal_imprinting0.81321346
110MP0000920_abnormal_myelination0.81271795
111MP0003698_abnormal_male_reproductive0.80858089
112MP0002132_abnormal_respiratory_system0.80611136
113MP0002148_abnormal_hypersensitivity_rea0.79804179
114MP0002972_abnormal_cardiac_muscle0.79377623
115MP0002269_muscular_atrophy0.78223502
116MP0002557_abnormal_social/conspecific_i0.78215531
117MP0002234_abnormal_pharynx_morphology0.77286989
118MP0000230_abnormal_systemic_arterial0.77225888
119MP0001270_distended_abdomen0.77215999
120MP0005084_abnormal_gallbladder_morpholo0.76781419
121MP0004036_abnormal_muscle_relaxation0.76486389
122MP0001963_abnormal_hearing_physiology0.76443501
123MP0000778_abnormal_nervous_system0.76249774
124MP0009745_abnormal_behavioral_response0.76187439
125MP0002229_neurodegeneration0.75234657
126MP0005670_abnormal_white_adipose0.74949356
127MP0001968_abnormal_touch/_nociception0.74698579
128MP0009046_muscle_twitch0.73403812
129MP0005266_abnormal_metabolism0.73393609
130MP0001835_abnormal_antigen_presentation0.72896586
131MP0002734_abnormal_mechanical_nocicepti0.72668963
132MP0006036_abnormal_mitochondrial_physio0.72316870
133MP0005187_abnormal_penis_morphology0.71378939
134MP0000613_abnormal_salivary_gland0.71363912
135MP0004270_analgesia0.71358906
136MP0000049_abnormal_middle_ear0.70027112
137MP0001905_abnormal_dopamine_level0.68938501
138MP0004484_altered_response_of0.68356495
139MP0008569_lethality_at_weaning0.68208286
140MP0001944_abnormal_pancreas_morphology0.67783057
141MP0005620_abnormal_muscle_contractility0.67644186
142MP0001186_pigmentation_phenotype0.67606560
143MP0000003_abnormal_adipose_tissue0.67361815
144MP0002736_abnormal_nociception_after0.66744343
145MP0001879_abnormal_lymphatic_vessel0.65850874

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)4.03094160
2Absent/shortened dynein arms (HP:0200106)4.03094160
3Hypothermia (HP:0002045)4.02366731
4White forelock (HP:0002211)3.98288108
5Abnormal hair whorl (HP:0010721)3.90097822
6Patchy hypopigmentation of hair (HP:0011365)3.87507661
7Hyperventilation (HP:0002883)3.36474247
8Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.29596137
9Medial flaring of the eyebrow (HP:0010747)3.02476222
10Subaortic stenosis (HP:0001682)2.90626647
11Abnormality of the left ventricular outflow tract (HP:0011103)2.90626647
12Congenital sensorineural hearing impairment (HP:0008527)2.90372700
13Absent speech (HP:0001344)2.84520900
14Chromosomal breakage induced by crosslinking agents (HP:0003221)2.83071543
15Genetic anticipation (HP:0003743)2.80302271
16Chromsome breakage (HP:0040012)2.78456037
17Abnormality of the right ventricle (HP:0001707)2.76455199
18True hermaphroditism (HP:0010459)2.75408745
19Papillary thyroid carcinoma (HP:0002895)2.74305496
20Exercise-induced myalgia (HP:0003738)2.69828666
21Muscle fiber inclusion bodies (HP:0100299)2.66429790
22Renal cortical cysts (HP:0000803)2.65368588
23Abnormal respiratory motile cilium morphology (HP:0005938)2.64629408
24Abnormal respiratory epithelium morphology (HP:0012253)2.64629408
25Decreased circulating renin level (HP:0003351)2.63890063
26Intestinal atresia (HP:0011100)2.61317795
27Hypoglycemic coma (HP:0001325)2.61144161
28Lip pit (HP:0100267)2.61084590
29Bell-shaped thorax (HP:0001591)2.60298267
30Nephrogenic diabetes insipidus (HP:0009806)2.60201599
31Abnormal ciliary motility (HP:0012262)2.57588261
32Volvulus (HP:0002580)2.56873196
33Hyperinsulinemic hypoglycemia (HP:0000825)2.54508306
34Nemaline bodies (HP:0003798)2.53606693
35Abnormal respiratory motile cilium physiology (HP:0012261)2.50011055
36Broad-based gait (HP:0002136)2.45915032
37Nephronophthisis (HP:0000090)2.45595729
38Gaze-evoked nystagmus (HP:0000640)2.43448473
39Abnormality of the corticospinal tract (HP:0002492)2.42416280
40Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.41612790
41Hypoplastic iliac wings (HP:0002866)2.41147161
42Neoplasm of the adrenal cortex (HP:0100641)2.40684889
43Molar tooth sign on MRI (HP:0002419)2.36957629
44Abnormality of midbrain morphology (HP:0002418)2.36957629
45Pancreatic fibrosis (HP:0100732)2.36645760
46Ketoacidosis (HP:0001993)2.36600161
47Retinal dysplasia (HP:0007973)2.34766290
48Exercise-induced muscle cramps (HP:0003710)2.34429077
49Febrile seizures (HP:0002373)2.33715093
50Amyotrophic lateral sclerosis (HP:0007354)2.32273716
51Thyroid carcinoma (HP:0002890)2.32236224
52Aplasia/Hypoplasia of the fovea (HP:0008060)2.31245342
53Hypoplasia of the fovea (HP:0007750)2.31245342
54Hypoglycemic seizures (HP:0002173)2.31243140
55Truncal obesity (HP:0001956)2.28993116
56Abnormality of the renal collecting system (HP:0004742)2.28149090
57Osteomalacia (HP:0002749)2.27532217
58Abnormality of incisor morphology (HP:0011063)2.27157428
59Abnormality of the renal cortex (HP:0011035)2.26091260
60Drooling (HP:0002307)2.24814229
61Abnormality of the renal medulla (HP:0100957)2.18908307
62Atrial fibrillation (HP:0005110)2.16695034
63Alveolar cell carcinoma (HP:0006519)2.15736849
64Absent eyebrow (HP:0002223)2.15382796
65Abnormality of the calf musculature (HP:0001430)2.14802162
66Aplasia/Hypoplasia of the lens (HP:0008063)2.14651410
67Abnormality of the nasolacrimal system (HP:0000614)2.14238208
68Rimmed vacuoles (HP:0003805)2.13637158
69Abnormal rod and cone electroretinograms (HP:0008323)2.13201701
70Atonic seizures (HP:0010819)2.12339166
71Submucous cleft hard palate (HP:0000176)2.12134312
72Congenital primary aphakia (HP:0007707)2.11713746
73Absent rod-and cone-mediated responses on ERG (HP:0007688)2.11518496
74Protruding tongue (HP:0010808)2.11442159
75Poor coordination (HP:0002370)2.10691283
76Excessive salivation (HP:0003781)2.08993190
77Median cleft lip (HP:0000161)2.08954659
78Gait imbalance (HP:0002141)2.08264069
79Conjugated hyperbilirubinemia (HP:0002908)2.08113229
80Pancreatic cysts (HP:0001737)2.07525809
81Papilledema (HP:0001085)2.07436982
82Prolonged QT interval (HP:0001657)2.07193898
83Hypoplastic ischia (HP:0003175)2.05777938
84Duplicated collecting system (HP:0000081)2.04254553
85Abnormality of the ischium (HP:0003174)2.04113697
86Aqueductal stenosis (HP:0002410)2.03310725
87Nasolacrimal duct obstruction (HP:0000579)2.02738611
88Abnormality of renal resorption (HP:0011038)2.02544323
89Ketosis (HP:0001946)2.02301199
90Metaphyseal dysplasia (HP:0100255)2.01450496
91Degeneration of the lateral corticospinal tracts (HP:0002314)2.00285399
92Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.00285399
93Hyperkalemia (HP:0002153)1.98749809
94Methylmalonic acidemia (HP:0002912)1.97405006
95Aplasia/Hypoplasia of the tibia (HP:0005772)1.97334143
96Abnormality of the fovea (HP:0000493)1.97095010
97Constricted visual fields (HP:0001133)1.96773418
98Calf muscle hypertrophy (HP:0008981)1.96589232
99Steppage gait (HP:0003376)1.94225542
100Congenital stationary night blindness (HP:0007642)1.94174372
101Menstrual irregularities (HP:0000858)1.94074350
102Long clavicles (HP:0000890)1.93912760
103Stomach cancer (HP:0012126)1.92377977
104Abnormality of the lacrimal duct (HP:0011481)1.92374274
105Attenuation of retinal blood vessels (HP:0007843)1.91655821
106Hyperglycemia (HP:0003074)1.91330310
107Hemiparesis (HP:0001269)1.90917075
108Myoglobinuria (HP:0002913)1.90657767
109Abnormality of the pancreatic islet cells (HP:0006476)1.89542792
110Abnormality of endocrine pancreas physiology (HP:0012093)1.89542792
111Genital tract atresia (HP:0001827)1.88731012
112Increased corneal curvature (HP:0100692)1.88572375
113Keratoconus (HP:0000563)1.88572375
114Aplasia cutis congenita (HP:0001057)1.86150297
115Primary atrial arrhythmia (HP:0001692)1.85607716
116Tubulointerstitial nephritis (HP:0001970)1.85343479
117Cupped ear (HP:0000378)1.85020624
118EMG: neuropathic changes (HP:0003445)1.84464755
119Abnormality of vitamin B metabolism (HP:0004340)1.83612309
120Vaginal atresia (HP:0000148)1.83113233
121Facial diplegia (HP:0001349)1.82959116
122Thyroiditis (HP:0100646)1.82340047
123Epileptic encephalopathy (HP:0200134)1.81181576
124Prostate neoplasm (HP:0100787)1.80998328
125Muscle hypertrophy of the lower extremities (HP:0008968)1.79990482
126Tented upper lip vermilion (HP:0010804)1.79950929
127Optic nerve hypoplasia (HP:0000609)1.78900007
128Testicular neoplasm (HP:0010788)1.77361280
129Downturned corners of mouth (HP:0002714)1.75806803
130Hypomagnesemia (HP:0002917)1.75757107
131Renal tubular dysfunction (HP:0000124)1.75468209
132Left ventricular hypertrophy (HP:0001712)1.75389279
133Nephropathy (HP:0000112)1.75101137
134Central scotoma (HP:0000603)1.75049106
135Bundle branch block (HP:0011710)1.74960200
136Chronic hepatic failure (HP:0100626)1.74704162
137Bradycardia (HP:0001662)1.74499070
138Progressive cerebellar ataxia (HP:0002073)1.74098199
139Dyschromatopsia (HP:0007641)1.73856381
140Short foot (HP:0001773)1.73693227
141Azoospermia (HP:0000027)1.72202960
142Postaxial foot polydactyly (HP:0001830)1.71444112
143Dyskinesia (HP:0100660)1.70048809
144Abnormality of the heme biosynthetic pathway (HP:0010472)1.69796316
145Renal Fanconi syndrome (HP:0001994)1.69202935
146Supraventricular tachycardia (HP:0004755)1.69057490
147Hypsarrhythmia (HP:0002521)1.68219409
148Prolonged bleeding time (HP:0003010)1.66957820
149Proximal tubulopathy (HP:0000114)1.66478578
150Blue irides (HP:0000635)1.65387031
151Agitation (HP:0000713)1.64576144
152Neoplasm of the tracheobronchial system (HP:0100552)1.64413511
153Xerostomia (HP:0000217)1.63898126
154Type I transferrin isoform profile (HP:0003642)1.63890869
155EEG with generalized epileptiform discharges (HP:0011198)1.63747111
156Congenital hepatic fibrosis (HP:0002612)1.63276501
157Hyperphosphatemia (HP:0002905)1.61978479
158Macroorchidism (HP:0000053)1.61804121
159Insulin-resistant diabetes mellitus (HP:0000831)1.61216955
160Abnormality of the nasal septum (HP:0000419)1.59998018
161Supraventricular arrhythmia (HP:0005115)1.57915918
162Type 2 muscle fiber atrophy (HP:0003554)1.57568221
163Aganglionic megacolon (HP:0002251)1.57244086
164Anteriorly placed anus (HP:0001545)1.57150670
165Abnormality of the columella (HP:0009929)1.57005466
166Symptomatic seizures (HP:0011145)1.56958745
167Widely spaced teeth (HP:0000687)1.55821843

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK3.38157696
2CASK3.15079646
3INSRR2.67123154
4BMPR22.60677122
5ACVR1B2.56210985
6MAP3K42.40558376
7NUAK12.23578833
8MAP3K142.03044811
9ZAK2.02699830
10BMPR1B2.02691676
11MAP4K22.02269962
12IRAK42.01760886
13IRAK11.96542628
14MAPK151.89448409
15FGFR21.86134934
16TAOK31.81832990
17PIK3CG1.81142685
18OBSCN1.77878962
19BRD41.75235730
20MUSK1.73741332
21EPHA31.72944259
22AKT31.71865369
23NEK61.65900308
24MARK11.64562611
25YES11.62585362
26PIK3CA1.60653139
27SGK21.58641433
28SIK31.55177532
29PRKD31.51142040
30LMTK21.48052998
31STK391.41229837
32MYLK1.36424213
33WNK11.33807167
34CDK31.27569805
35PRPF4B1.27095515
36EIF2AK31.26381540
37CLK11.25222886
38HIPK21.25219301
39ERBB31.24560000
40NTRK31.22915388
41IRAK31.22658712
42STK241.20069913
43MAP3K71.18858859
44DMPK1.18154397
45SGK2231.15861777
46SGK4941.15861777
47PRKCE1.12774887
48MAP3K21.12245855
49PAK31.12080238
50CDC42BPA1.11260701
51MAPKAPK51.11026533
52STK161.10672023
53MAP2K41.10638583
54TRPM71.09279704
55TXK1.04470397
56MAPK131.03730241
57STK31.03299105
58FGFR31.02337650
59GRK71.02182960
60WNK41.01361123
61PNCK1.00024454
62FRK0.98284201
63TEC0.97835639
64RIPK40.93905657
65EIF2AK20.93344204
66WNK30.91411455
67NME10.87204227
68CAMKK20.86043718
69PTK2B0.85221261
70ADRBK20.83653867
71GRK10.83079278
72RPS6KA20.81904911
73SGK30.80761361
74RPS6KL10.80360400
75RPS6KC10.80360400
76DAPK20.80163094
77DYRK1A0.79841383
78MAP2K70.79723386
79TRIM280.78639183
80IRAK20.78424510
81BRSK20.78337677
82CAMK2D0.78268825
83PIM20.78162003
84CDK80.76296661
85NLK0.75116125
86PRKG20.74543556
87CSNK1G20.74116913
88KIT0.73637224
89BCR0.73634115
90RPS6KA60.72800084
91TIE10.68665583
92MAP3K120.67807439
93MAPK120.66329912
94FER0.62969456
95PLK20.62474680
96STK110.61270712
97TNK20.60846794
98PASK0.60079591
99PRKG10.60065819
100PRKAA10.58455513
101MAPK70.56226614
102CAMK2A0.55566679
103PKN10.54765194
104PRKCQ0.54196777
105PINK10.53962876
106CAMK10.53568570
107SGK10.53532691
108CAMK1G0.51661400
109CSNK1G10.50712855
110IKBKE0.50341194
111MKNK10.48298223
112NTRK20.48224919
113PRKAA20.47156573
114VRK10.46983453
115CDK190.46810424
116IKBKB0.46244509
117TGFBR20.46097806
118UHMK10.45809773
119NEK90.45508233
120PHKG20.44642900
121PHKG10.44642900
122MKNK20.44487854
123CAMK40.44267044
124CAMK2B0.44053018
125CHUK0.43827948
126MAP2K60.43766938
127OXSR10.43694830
128PRKACA0.43443425
129MARK30.43352105
130JAK30.43149363
131PRKCG0.42745913
132CSNK1G30.42407596
133RPS6KA50.41351162
134STK38L0.41076574
135MARK20.41034075
136RPS6KB10.39596205
137FLT30.39219194
138STK380.37785068
139CSNK1D0.37573746
140BTK0.37056793
141TGFBR10.36510750
142MAP3K60.35945662
143ADRBK10.34580708
144PDK30.32798320

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.48079280
2Dorso-ventral axis formation_Homo sapiens_hsa043202.56381648
3Butanoate metabolism_Homo sapiens_hsa006502.49143465
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.30634909
5SNARE interactions in vesicular transport_Homo sapiens_hsa041302.15073573
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.03737257
7Taste transduction_Homo sapiens_hsa047421.98841447
8Phototransduction_Homo sapiens_hsa047441.95031086
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.90635280
10Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.87107094
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.84087096
12Serotonergic synapse_Homo sapiens_hsa047261.62914849
13Insulin secretion_Homo sapiens_hsa049111.62480462
14Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.62008878
15Sphingolipid metabolism_Homo sapiens_hsa006001.59819391
16Circadian entrainment_Homo sapiens_hsa047131.52210808
17Propanoate metabolism_Homo sapiens_hsa006401.48909816
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.48846769
19Morphine addiction_Homo sapiens_hsa050321.42613503
20Nicotine addiction_Homo sapiens_hsa050331.33781282
21Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.33634123
22Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.31971916
23Nitrogen metabolism_Homo sapiens_hsa009101.27195146
24Dilated cardiomyopathy_Homo sapiens_hsa054141.22477257
25Oxidative phosphorylation_Homo sapiens_hsa001901.21455814
26Calcium signaling pathway_Homo sapiens_hsa040201.19636647
27Amphetamine addiction_Homo sapiens_hsa050311.16546360
28Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.15358727
29Circadian rhythm_Homo sapiens_hsa047101.14771321
30Glutamatergic synapse_Homo sapiens_hsa047241.13860750
31Cardiac muscle contraction_Homo sapiens_hsa042601.13592564
32Olfactory transduction_Homo sapiens_hsa047401.13586903
33Vibrio cholerae infection_Homo sapiens_hsa051101.13250084
34Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.10810567
35Platelet activation_Homo sapiens_hsa046111.09594688
36Fatty acid biosynthesis_Homo sapiens_hsa000611.08593279
37Fanconi anemia pathway_Homo sapiens_hsa034601.06116638
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.03472244
39Ether lipid metabolism_Homo sapiens_hsa005651.03327977
40Alzheimers disease_Homo sapiens_hsa050101.01201109
41mTOR signaling pathway_Homo sapiens_hsa041501.00966817
42Fatty acid elongation_Homo sapiens_hsa000621.00886364
43Sulfur metabolism_Homo sapiens_hsa009201.00749399
44cAMP signaling pathway_Homo sapiens_hsa040240.98039959
45Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.94903221
46Cholinergic synapse_Homo sapiens_hsa047250.93248903
47Glucagon signaling pathway_Homo sapiens_hsa049220.90783973
48Rheumatoid arthritis_Homo sapiens_hsa053230.90606432
49Renin secretion_Homo sapiens_hsa049240.89492145
50Gastric acid secretion_Homo sapiens_hsa049710.88934825
51Autoimmune thyroid disease_Homo sapiens_hsa053200.88749422
52Glycerophospholipid metabolism_Homo sapiens_hsa005640.87805887
53Arachidonic acid metabolism_Homo sapiens_hsa005900.87668435
54Regulation of autophagy_Homo sapiens_hsa041400.87276892
55Pancreatic secretion_Homo sapiens_hsa049720.87172023
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.86521103
57Selenocompound metabolism_Homo sapiens_hsa004500.85729491
58Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85048245
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.83248671
60Fatty acid metabolism_Homo sapiens_hsa012120.82732928
61FoxO signaling pathway_Homo sapiens_hsa040680.81854796
62Tryptophan metabolism_Homo sapiens_hsa003800.81791437
63GABAergic synapse_Homo sapiens_hsa047270.81328896
64Ovarian steroidogenesis_Homo sapiens_hsa049130.80788938
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.79941699
66Dopaminergic synapse_Homo sapiens_hsa047280.79773811
67Glycosaminoglycan degradation_Homo sapiens_hsa005310.79757602
68Collecting duct acid secretion_Homo sapiens_hsa049660.79317760
69Insulin resistance_Homo sapiens_hsa049310.79127934
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.77170841
71Peroxisome_Homo sapiens_hsa041460.76878130
72Huntingtons disease_Homo sapiens_hsa050160.75523294
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.75364778
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74259731
75Lysine degradation_Homo sapiens_hsa003100.73890497
76Cocaine addiction_Homo sapiens_hsa050300.73601168
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73139093
78ABC transporters_Homo sapiens_hsa020100.72892569
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72777498
80Fatty acid degradation_Homo sapiens_hsa000710.71009582
81Axon guidance_Homo sapiens_hsa043600.69462130
82Parkinsons disease_Homo sapiens_hsa050120.68997656
83Oocyte meiosis_Homo sapiens_hsa041140.68844513
84Hematopoietic cell lineage_Homo sapiens_hsa046400.68653089
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.68591657
86beta-Alanine metabolism_Homo sapiens_hsa004100.68131809
87Phagosome_Homo sapiens_hsa041450.68126110
88Linoleic acid metabolism_Homo sapiens_hsa005910.67320553
89N-Glycan biosynthesis_Homo sapiens_hsa005100.66145691
90Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65071349
91Measles_Homo sapiens_hsa051620.64780558
92Type II diabetes mellitus_Homo sapiens_hsa049300.64350819
93Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.64019815
94Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63964362
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62486838
96Mineral absorption_Homo sapiens_hsa049780.62174568
97Long-term potentiation_Homo sapiens_hsa047200.61477297
98Basal transcription factors_Homo sapiens_hsa030220.60169369
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60100509
100Salivary secretion_Homo sapiens_hsa049700.59340719
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59056089
102Prolactin signaling pathway_Homo sapiens_hsa049170.58700745
103ECM-receptor interaction_Homo sapiens_hsa045120.58672475
104Insulin signaling pathway_Homo sapiens_hsa049100.58644703
105Choline metabolism in cancer_Homo sapiens_hsa052310.58551951
106Aldosterone synthesis and secretion_Homo sapiens_hsa049250.58540890
107RNA degradation_Homo sapiens_hsa030180.58462051
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58287709
109Long-term depression_Homo sapiens_hsa047300.57862460
110Intestinal immune network for IgA production_Homo sapiens_hsa046720.55387614
111Protein digestion and absorption_Homo sapiens_hsa049740.54814093
112Other glycan degradation_Homo sapiens_hsa005110.54584621
113GnRH signaling pathway_Homo sapiens_hsa049120.53905112
114AMPK signaling pathway_Homo sapiens_hsa041520.53661994
115Toll-like receptor signaling pathway_Homo sapiens_hsa046200.53059725
116Jak-STAT signaling pathway_Homo sapiens_hsa046300.52766009
117Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.51895147
118Inositol phosphate metabolism_Homo sapiens_hsa005620.51002489
119Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50945325
120Ras signaling pathway_Homo sapiens_hsa040140.50457934
121Gap junction_Homo sapiens_hsa045400.49415025
122Oxytocin signaling pathway_Homo sapiens_hsa049210.48736868
123Non-homologous end-joining_Homo sapiens_hsa034500.48598476
124Leishmaniasis_Homo sapiens_hsa051400.47278458
125Melanoma_Homo sapiens_hsa052180.47218523
126Purine metabolism_Homo sapiens_hsa002300.46951985
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.46737833
128NF-kappa B signaling pathway_Homo sapiens_hsa040640.46009948
129Transcriptional misregulation in cancer_Homo sapiens_hsa052020.45459211
130Wnt signaling pathway_Homo sapiens_hsa043100.45173999
131Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.44513766
132Malaria_Homo sapiens_hsa051440.44471386
133Histidine metabolism_Homo sapiens_hsa003400.44235697
134PI3K-Akt signaling pathway_Homo sapiens_hsa041510.44202873
135Glycerolipid metabolism_Homo sapiens_hsa005610.43521134
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41856635
137MAPK signaling pathway_Homo sapiens_hsa040100.41490991
138Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.41429507
139Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41217409
140Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.40966714
141Primary bile acid biosynthesis_Homo sapiens_hsa001200.40914967
142Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38283941
143T cell receptor signaling pathway_Homo sapiens_hsa046600.37001171

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