Rank | Gene Set | Z-score |
---|---|---|
1 | inositol phosphate catabolic process (GO:0071545) | 5.80874750 |
2 | inositol phosphate dephosphorylation (GO:0046855) | 5.48827251 |
3 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 5.48827251 |
4 | establishment of protein localization to Golgi (GO:0072600) | 4.64839936 |
5 | protein targeting to Golgi (GO:0000042) | 4.50613035 |
6 | polyol catabolic process (GO:0046174) | 4.31675021 |
7 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 4.20647946 |
8 | piRNA metabolic process (GO:0034587) | 4.08839899 |
9 | protein localization to Golgi apparatus (GO:0034067) | 4.04230794 |
10 | polyketide metabolic process (GO:0030638) | 3.92524736 |
11 | doxorubicin metabolic process (GO:0044598) | 3.92524736 |
12 | daunorubicin metabolic process (GO:0044597) | 3.92524736 |
13 | energy homeostasis (GO:0097009) | 3.67910598 |
14 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.61075245 |
15 | interkinetic nuclear migration (GO:0022027) | 3.55546076 |
16 | inositol metabolic process (GO:0006020) | 3.54077396 |
17 | epithelial cilium movement (GO:0003351) | 3.47044304 |
18 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.41364621 |
19 | acrosome reaction (GO:0007340) | 3.39394671 |
20 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.37891076 |
21 | neural tube formation (GO:0001841) | 3.37526363 |
22 | response to pheromone (GO:0019236) | 3.37393357 |
23 | DNA methylation involved in gamete generation (GO:0043046) | 3.29543709 |
24 | protein K11-linked deubiquitination (GO:0035871) | 3.23148726 |
25 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.21728240 |
26 | signal peptide processing (GO:0006465) | 3.15807886 |
27 | presynaptic membrane assembly (GO:0097105) | 3.14832142 |
28 | short-chain fatty acid metabolic process (GO:0046459) | 3.13903331 |
29 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.13339302 |
30 | definitive hemopoiesis (GO:0060216) | 3.12122415 |
31 | detection of calcium ion (GO:0005513) | 3.08287520 |
32 | cellular ketone body metabolic process (GO:0046950) | 3.06234483 |
33 | intra-Golgi vesicle-mediated transport (GO:0006891) | 2.99872847 |
34 | photoreceptor cell differentiation (GO:0046530) | 2.96570564 |
35 | eye photoreceptor cell differentiation (GO:0001754) | 2.96570564 |
36 | positive regulation of meiosis (GO:0045836) | 2.96116011 |
37 | intraciliary transport (GO:0042073) | 2.94567302 |
38 | phospholipid dephosphorylation (GO:0046839) | 2.93963551 |
39 | phosphatidylinositol dephosphorylation (GO:0046856) | 2.88675905 |
40 | ketone body metabolic process (GO:1902224) | 2.87650404 |
41 | sperm motility (GO:0030317) | 2.87491325 |
42 | negative regulation of exocytosis (GO:0045920) | 2.84664575 |
43 | regulation of pigment cell differentiation (GO:0050932) | 2.84472786 |
44 | regulation of meiosis I (GO:0060631) | 2.84165566 |
45 | protein prenylation (GO:0018342) | 2.83377754 |
46 | prenylation (GO:0097354) | 2.83377754 |
47 | presynaptic membrane organization (GO:0097090) | 2.83250340 |
48 | positive regulation of granulocyte differentiation (GO:0030854) | 2.79235439 |
49 | microtubule nucleation (GO:0007020) | 2.79049946 |
50 | regulation of hexokinase activity (GO:1903299) | 2.78704664 |
51 | regulation of glucokinase activity (GO:0033131) | 2.78704664 |
52 | cilium movement (GO:0003341) | 2.75524906 |
53 | axonemal dynein complex assembly (GO:0070286) | 2.74695813 |
54 | early endosome to late endosome transport (GO:0045022) | 2.73863768 |
55 | GPI anchor biosynthetic process (GO:0006506) | 2.73044947 |
56 | histone H3-K4 trimethylation (GO:0080182) | 2.72416931 |
57 | positive regulation of action potential (GO:0045760) | 2.70722809 |
58 | detection of light stimulus involved in visual perception (GO:0050908) | 2.69612813 |
59 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.69612813 |
60 | positive regulation of meiotic cell cycle (GO:0051446) | 2.68072457 |
61 | pharyngeal system development (GO:0060037) | 2.66645950 |
62 | regulation of skeletal muscle contraction (GO:0014819) | 2.65824088 |
63 | axoneme assembly (GO:0035082) | 2.64693186 |
64 | urinary tract smooth muscle contraction (GO:0014848) | 2.64304984 |
65 | negative regulation of protein oligomerization (GO:0032460) | 2.63143773 |
66 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.61624866 |
67 | Golgi to endosome transport (GO:0006895) | 2.60031348 |
68 | negative regulation of osteoblast proliferation (GO:0033689) | 2.58996750 |
69 | positive regulation of glycolytic process (GO:0045821) | 2.58742983 |
70 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.57643840 |
71 | regulation of protein glycosylation (GO:0060049) | 2.57277538 |
72 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.57136427 |
73 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.57136427 |
74 | dentate gyrus development (GO:0021542) | 2.56795545 |
75 | auditory behavior (GO:0031223) | 2.56483950 |
76 | nucleotide transmembrane transport (GO:1901679) | 2.55717353 |
77 | reflex (GO:0060004) | 2.55628923 |
78 | nerve growth factor signaling pathway (GO:0038180) | 2.54967812 |
79 | cell differentiation involved in metanephros development (GO:0072202) | 2.53516514 |
80 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.53474806 |
81 | dendritic spine morphogenesis (GO:0060997) | 2.53332935 |
82 | cAMP catabolic process (GO:0006198) | 2.52397621 |
83 | dopamine transport (GO:0015872) | 2.50050520 |
84 | parental behavior (GO:0060746) | 2.49287861 |
85 | negative regulation of transcription by competitive promoter binding (GO:0010944) | 2.48977089 |
86 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.48763487 |
87 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.48747332 |
88 | protein localization to cilium (GO:0061512) | 2.48497210 |
89 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.46543334 |
90 | cytidine deamination (GO:0009972) | 2.45446802 |
91 | cytidine metabolic process (GO:0046087) | 2.45446802 |
92 | cytidine catabolic process (GO:0006216) | 2.45446802 |
93 | GPI anchor metabolic process (GO:0006505) | 2.45072020 |
94 | acrosome assembly (GO:0001675) | 2.45030883 |
95 | regulation of relaxation of muscle (GO:1901077) | 2.44999017 |
96 | left/right pattern formation (GO:0060972) | 2.43910309 |
97 | RNA destabilization (GO:0050779) | 2.43819628 |
98 | sperm capacitation (GO:0048240) | 2.42025483 |
99 | regulation of Rac protein signal transduction (GO:0035020) | 2.41613100 |
100 | multicellular organism reproduction (GO:0032504) | 2.41352757 |
101 | photoreceptor cell maintenance (GO:0045494) | 2.40441383 |
102 | protein-chromophore linkage (GO:0018298) | 2.39986113 |
103 | calcium ion import (GO:0070509) | 2.39077281 |
104 | peripheral nervous system neuron development (GO:0048935) | 2.38466017 |
105 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.38233557 |
106 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.37649220 |
107 | proline transport (GO:0015824) | 2.37640607 |
108 | regulation of sarcomere organization (GO:0060297) | 2.37299284 |
109 | nonmotile primary cilium assembly (GO:0035058) | 2.36464178 |
110 | negative regulation of gluconeogenesis (GO:0045721) | 2.35676170 |
111 | spermatid nucleus differentiation (GO:0007289) | 2.35661755 |
112 | ether lipid metabolic process (GO:0046485) | 2.35561291 |
113 | histone H2A ubiquitination (GO:0033522) | 2.35238550 |
114 | sympathetic nervous system development (GO:0048485) | 2.34130393 |
115 | facial nerve structural organization (GO:0021612) | 2.33275473 |
116 | regulation of cell communication by electrical coupling (GO:0010649) | 2.32815848 |
117 | glycosphingolipid biosynthetic process (GO:0006688) | 2.32453355 |
118 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.31804737 |
119 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.31804737 |
120 | negative regulation of dendrite development (GO:2000171) | 2.31611156 |
121 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 2.31550245 |
122 | nucleus localization (GO:0051647) | 2.30676106 |
123 | regulation of female gonad development (GO:2000194) | 2.30546052 |
124 | postsynaptic membrane organization (GO:0001941) | 2.30240287 |
125 | cilium assembly (GO:0042384) | 2.30040004 |
126 | gene silencing by RNA (GO:0031047) | 2.29645187 |
127 | nucleoside diphosphate catabolic process (GO:0009134) | 2.28915460 |
128 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.28766481 |
129 | negative regulation of JUN kinase activity (GO:0043508) | 2.28012105 |
130 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.27700743 |
131 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 2.27206108 |
132 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 2.27206108 |
133 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 2.26733266 |
134 | microtubule anchoring (GO:0034453) | 2.26246473 |
135 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.25343626 |
136 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.25343626 |
137 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.24698763 |
138 | ganglion development (GO:0061548) | 2.24654717 |
139 | righting reflex (GO:0060013) | 2.24257976 |
140 | inner ear receptor stereocilium organization (GO:0060122) | 2.23799301 |
141 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.23549524 |
142 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.23307069 |
143 | regulation of memory T cell differentiation (GO:0043380) | 2.23074014 |
144 | positive regulation of steroid hormone secretion (GO:2000833) | 2.22653975 |
145 | extracellular regulation of signal transduction (GO:1900115) | 2.22048387 |
146 | extracellular negative regulation of signal transduction (GO:1900116) | 2.22048387 |
147 | phosphatidylinositol phosphorylation (GO:0046854) | 2.21801220 |
148 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 2.21758263 |
149 | cilium organization (GO:0044782) | 2.21236760 |
150 | adaptation of signaling pathway (GO:0023058) | 2.19913865 |
151 | regulation of germinal center formation (GO:0002634) | 2.19893379 |
152 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.19891670 |
153 | myofibril assembly (GO:0030239) | 2.19788316 |
154 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.19192603 |
155 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.19192603 |
156 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.19192603 |
157 | retina layer formation (GO:0010842) | 2.18765976 |
158 | parturition (GO:0007567) | 2.17828775 |
159 | inner ear receptor cell differentiation (GO:0060113) | 2.16484581 |
160 | nitric oxide mediated signal transduction (GO:0007263) | 2.15736501 |
161 | response to epinephrine (GO:0071871) | 2.14936432 |
162 | mannosylation (GO:0097502) | 2.14310740 |
163 | cyclic nucleotide catabolic process (GO:0009214) | 2.14154126 |
164 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 2.13927080 |
165 | superoxide anion generation (GO:0042554) | 2.13421085 |
166 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.13049640 |
167 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.11934178 |
168 | cranial nerve structural organization (GO:0021604) | 2.11623225 |
169 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.10911137 |
170 | motile cilium assembly (GO:0044458) | 2.10755136 |
171 | developmental pigmentation (GO:0048066) | 2.10745795 |
172 | negative regulation of neurotransmitter transport (GO:0051589) | 2.10270230 |
173 | ER overload response (GO:0006983) | 2.08978349 |
174 | response to redox state (GO:0051775) | 2.08869029 |
175 | mechanoreceptor differentiation (GO:0042490) | 2.07452316 |
176 | heart contraction (GO:0060047) | 2.07122835 |
177 | heart process (GO:0003015) | 2.07122835 |
178 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.07116425 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.72840956 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.95385284 |
3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.64945033 |
4 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.56850722 |
5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.47005074 |
6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.37530031 |
7 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.29494149 |
8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.27667609 |
9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.23266624 |
10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.18622244 |
11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.04333167 |
12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.99841001 |
13 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.89951197 |
14 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.89066933 |
15 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.85916710 |
16 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.85168071 |
17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.84807265 |
18 | VDR_22108803_ChIP-Seq_LS180_Human | 1.81846428 |
19 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.80498189 |
20 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.79265406 |
21 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.78435332 |
22 | P300_19829295_ChIP-Seq_ESCs_Human | 1.74703413 |
23 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.73279992 |
24 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.72589643 |
25 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.72087401 |
26 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.70412413 |
27 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.68165723 |
28 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.67856504 |
29 | * SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.67735215 |
30 | * EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.64984693 |
31 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.60875280 |
32 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.59999618 |
33 | * STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.59458144 |
34 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.59313752 |
35 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.56295984 |
36 | FUS_26573619_Chip-Seq_HEK293_Human | 1.55344638 |
37 | * P300_18555785_Chip-Seq_ESCs_Mouse | 1.54390969 |
38 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.54242735 |
39 | * SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.51399231 |
40 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.51097344 |
41 | * NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.50838010 |
42 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.48554287 |
43 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.48452318 |
44 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.48233084 |
45 | * EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.47952083 |
46 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.45817753 |
47 | * OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.44566136 |
48 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.44029644 |
49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.43282716 |
50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.43282716 |
51 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.40801178 |
52 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.40797717 |
53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.40640401 |
54 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.39738524 |
55 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.39572937 |
56 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.37616998 |
57 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.37194662 |
58 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.37031244 |
59 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.35891813 |
60 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.35779266 |
61 | * RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.35699007 |
62 | * PU1_27457419_Chip-Seq_LIVER_Mouse | 1.34613271 |
63 | * ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.33880579 |
64 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.33827171 |
65 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.33133728 |
66 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.33095260 |
67 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32942933 |
68 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.32942933 |
69 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.32319693 |
70 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.32266487 |
71 | * KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.30271185 |
72 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.30076053 |
73 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.29842577 |
74 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.29513085 |
75 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.29309691 |
76 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29243452 |
77 | * CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.28973212 |
78 | TCF4_23295773_ChIP-Seq_U87_Human | 1.28955481 |
79 | EWS_26573619_Chip-Seq_HEK293_Human | 1.27664987 |
80 | STAT3_23295773_ChIP-Seq_U87_Human | 1.26728314 |
81 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.26597908 |
82 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.26042467 |
83 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.25817741 |
84 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.25561918 |
85 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.24646206 |
86 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.24620602 |
87 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.24524247 |
88 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.24204455 |
89 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.24204455 |
90 | * ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.23122873 |
91 | GATA1_22025678_ChIP-Seq_K562_Human | 1.22386139 |
92 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.22063315 |
93 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21112774 |
94 | * SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.20218762 |
95 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.20151745 |
96 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.20106102 |
97 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.20079727 |
98 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.18950127 |
99 | KDM2B_26808549_Chip-Seq_REH_Human | 1.18824444 |
100 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.18768851 |
101 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.18391880 |
102 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.16458647 |
103 | AR_25329375_ChIP-Seq_VCAP_Human | 1.16212221 |
104 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.14594542 |
105 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.13589912 |
106 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.12911022 |
107 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12882748 |
108 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.12867828 |
109 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.12672967 |
110 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.12414217 |
111 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12083854 |
112 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.12036303 |
113 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.11764592 |
114 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.11282701 |
115 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.11026222 |
116 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10603898 |
117 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.10333474 |
118 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.10057170 |
119 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.09854726 |
120 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.09818077 |
121 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.08794585 |
122 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.08235208 |
123 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07566231 |
124 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.06527505 |
125 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.06527505 |
126 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.05807182 |
127 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.05308158 |
128 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.03797225 |
129 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01493331 |
130 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.01033796 |
131 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99289888 |
132 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.99221349 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001188_hyperpigmentation | 3.22729566 |
2 | MP0005410_abnormal_fertilization | 2.85047980 |
3 | MP0005409_darkened_coat_color | 2.76773058 |
4 | MP0003183_abnormal_peptide_metabolism | 2.71826467 |
5 | MP0005646_abnormal_pituitary_gland | 2.68037752 |
6 | MP0005379_endocrine/exocrine_gland_phen | 2.64707576 |
7 | MP0005171_absent_coat_pigmentation | 2.60879706 |
8 | MP0002822_catalepsy | 2.60516681 |
9 | MP0002837_dystrophic_cardiac_calcinosis | 2.58678213 |
10 | MP0002638_abnormal_pupillary_reflex | 2.46003652 |
11 | MP0010386_abnormal_urinary_bladder | 2.29568467 |
12 | MP0001986_abnormal_taste_sensitivity | 2.25303589 |
13 | MP0002928_abnormal_bile_duct | 2.22381001 |
14 | MP0003646_muscle_fatigue | 2.19992478 |
15 | MP0005083_abnormal_biliary_tract | 2.18006548 |
16 | MP0003011_delayed_dark_adaptation | 2.13971136 |
17 | MP0008057_abnormal_DNA_replication | 2.12728250 |
18 | MP0002009_preneoplasia | 2.11999677 |
19 | MP0000015_abnormal_ear_pigmentation | 2.06102469 |
20 | MP0005645_abnormal_hypothalamus_physiol | 2.00857111 |
21 | MP0005174_abnormal_tail_pigmentation | 1.99092642 |
22 | MP0003195_calcinosis | 1.96537250 |
23 | MP0008995_early_reproductive_senescence | 1.91444670 |
24 | MP0003136_yellow_coat_color | 1.76548633 |
25 | MP0000566_synostosis | 1.75946544 |
26 | MP0000372_irregular_coat_pigmentation | 1.72974720 |
27 | MP0001502_abnormal_circadian_rhythm | 1.66683588 |
28 | MP0001984_abnormal_olfaction | 1.64923090 |
29 | MP0004859_abnormal_synaptic_plasticity | 1.64870181 |
30 | MP0002938_white_spotting | 1.64205047 |
31 | MP0002163_abnormal_gland_morphology | 1.62297932 |
32 | MP0003724_increased_susceptibility_to | 1.61324669 |
33 | MP0002102_abnormal_ear_morphology | 1.58715871 |
34 | MP0004381_abnormal_hair_follicle | 1.58409069 |
35 | MP0000749_muscle_degeneration | 1.57881631 |
36 | MP0006292_abnormal_olfactory_placode | 1.56261269 |
37 | MP0005551_abnormal_eye_electrophysiolog | 1.50949203 |
38 | MP0000427_abnormal_hair_cycle | 1.50642877 |
39 | MP0002735_abnormal_chemical_nociception | 1.47726737 |
40 | MP0004084_abnormal_cardiac_muscle | 1.45210331 |
41 | MP0003121_genomic_imprinting | 1.44223008 |
42 | MP0009697_abnormal_copulation | 1.43068097 |
43 | MP0004130_abnormal_muscle_cell | 1.40663230 |
44 | MP0006072_abnormal_retinal_apoptosis | 1.40638048 |
45 | MP0002876_abnormal_thyroid_physiology | 1.39807216 |
46 | MP0005075_abnormal_melanosome_morpholog | 1.38839104 |
47 | MP0004215_abnormal_myocardial_fiber | 1.38471412 |
48 | MP0003950_abnormal_plasma_membrane | 1.37213801 |
49 | MP0003656_abnormal_erythrocyte_physiolo | 1.32460531 |
50 | MP0004924_abnormal_behavior | 1.28210142 |
51 | MP0005386_behavior/neurological_phenoty | 1.28210142 |
52 | MP0003045_fibrosis | 1.28006438 |
53 | MP0003943_abnormal_hepatobiliary_system | 1.26576632 |
54 | MP0004147_increased_porphyrin_level | 1.24748334 |
55 | MP0005503_abnormal_tendon_morphology | 1.23513691 |
56 | MP0005253_abnormal_eye_physiology | 1.22531256 |
57 | MP0004742_abnormal_vestibular_system | 1.21791454 |
58 | MP0005220_abnormal_exocrine_pancreas | 1.21423604 |
59 | MP0003635_abnormal_synaptic_transmissio | 1.20681823 |
60 | MP0001764_abnormal_homeostasis | 1.19525195 |
61 | MP0002095_abnormal_skin_pigmentation | 1.19198602 |
62 | MP0002272_abnormal_nervous_system | 1.18815130 |
63 | MP0001486_abnormal_startle_reflex | 1.18236692 |
64 | MP0003880_abnormal_central_pattern | 1.17817879 |
65 | MP0000383_abnormal_hair_follicle | 1.17431579 |
66 | MP0004885_abnormal_endolymph | 1.13877637 |
67 | MP0001346_abnormal_lacrimal_gland | 1.12101156 |
68 | MP0002106_abnormal_muscle_physiology | 1.11093705 |
69 | MP0002693_abnormal_pancreas_physiology | 1.10933890 |
70 | MP0000631_abnormal_neuroendocrine_gland | 1.06789474 |
71 | MP0002063_abnormal_learning/memory/cond | 1.06012109 |
72 | MP0009780_abnormal_chondrocyte_physiolo | 1.04335772 |
73 | MP0008877_abnormal_DNA_methylation | 1.04313061 |
74 | MP0006276_abnormal_autonomic_nervous | 1.02022608 |
75 | MP0002877_abnormal_melanocyte_morpholog | 1.01922291 |
76 | MP0000013_abnormal_adipose_tissue | 1.01776313 |
77 | MP0004043_abnormal_pH_regulation | 0.98895429 |
78 | MP0000516_abnormal_urinary_system | 0.96167114 |
79 | MP0005367_renal/urinary_system_phenotyp | 0.96167114 |
80 | MP0004145_abnormal_muscle_electrophysio | 0.94797069 |
81 | MP0001501_abnormal_sleep_pattern | 0.93876749 |
82 | MP0002572_abnormal_emotion/affect_behav | 0.93769979 |
83 | MP0002909_abnormal_adrenal_gland | 0.93768825 |
84 | MP0004134_abnormal_chest_morphology | 0.93490576 |
85 | MP0008775_abnormal_heart_ventricle | 0.92202606 |
86 | MP0002277_abnormal_respiratory_mucosa | 0.92117460 |
87 | MP0002064_seizures | 0.91804754 |
88 | MP0005423_abnormal_somatic_nervous | 0.91794390 |
89 | MP0004085_abnormal_heartbeat | 0.91429620 |
90 | MP0002067_abnormal_sensory_capabilities | 0.91331234 |
91 | MP0005369_muscle_phenotype | 0.91082242 |
92 | MP0000681_abnormal_thyroid_gland | 0.90263104 |
93 | MP0003890_abnormal_embryonic-extraembry | 0.90220650 |
94 | MP0005085_abnormal_gallbladder_physiolo | 0.89445489 |
95 | MP0001485_abnormal_pinna_reflex | 0.89443237 |
96 | MP0000569_abnormal_digit_pigmentation | 0.88939156 |
97 | MP0003787_abnormal_imprinting | 0.88228110 |
98 | MP0002078_abnormal_glucose_homeostasis | 0.86812140 |
99 | MP0000751_myopathy | 0.86460319 |
100 | MP0002177_abnormal_outer_ear | 0.83633574 |
101 | MP0000026_abnormal_inner_ear | 0.83585975 |
102 | MP0000678_abnormal_parathyroid_gland | 0.83563305 |
103 | MP0005535_abnormal_body_temperature | 0.82917552 |
104 | MP0002127_abnormal_cardiovascular_syste | 0.82846848 |
105 | MP0000538_abnormal_urinary_bladder | 0.82434649 |
106 | MP0001929_abnormal_gametogenesis | 0.82139893 |
107 | MP0004142_abnormal_muscle_tone | 0.82062772 |
108 | MP0009250_abnormal_appendicular_skeleto | 0.81564837 |
109 | MP0003122_maternal_imprinting | 0.81321346 |
110 | MP0000920_abnormal_myelination | 0.81271795 |
111 | MP0003698_abnormal_male_reproductive | 0.80858089 |
112 | MP0002132_abnormal_respiratory_system | 0.80611136 |
113 | MP0002148_abnormal_hypersensitivity_rea | 0.79804179 |
114 | MP0002972_abnormal_cardiac_muscle | 0.79377623 |
115 | MP0002269_muscular_atrophy | 0.78223502 |
116 | MP0002557_abnormal_social/conspecific_i | 0.78215531 |
117 | MP0002234_abnormal_pharynx_morphology | 0.77286989 |
118 | MP0000230_abnormal_systemic_arterial | 0.77225888 |
119 | MP0001270_distended_abdomen | 0.77215999 |
120 | MP0005084_abnormal_gallbladder_morpholo | 0.76781419 |
121 | MP0004036_abnormal_muscle_relaxation | 0.76486389 |
122 | MP0001963_abnormal_hearing_physiology | 0.76443501 |
123 | MP0000778_abnormal_nervous_system | 0.76249774 |
124 | MP0009745_abnormal_behavioral_response | 0.76187439 |
125 | MP0002229_neurodegeneration | 0.75234657 |
126 | MP0005670_abnormal_white_adipose | 0.74949356 |
127 | MP0001968_abnormal_touch/_nociception | 0.74698579 |
128 | MP0009046_muscle_twitch | 0.73403812 |
129 | MP0005266_abnormal_metabolism | 0.73393609 |
130 | MP0001835_abnormal_antigen_presentation | 0.72896586 |
131 | MP0002734_abnormal_mechanical_nocicepti | 0.72668963 |
132 | MP0006036_abnormal_mitochondrial_physio | 0.72316870 |
133 | MP0005187_abnormal_penis_morphology | 0.71378939 |
134 | MP0000613_abnormal_salivary_gland | 0.71363912 |
135 | MP0004270_analgesia | 0.71358906 |
136 | MP0000049_abnormal_middle_ear | 0.70027112 |
137 | MP0001905_abnormal_dopamine_level | 0.68938501 |
138 | MP0004484_altered_response_of | 0.68356495 |
139 | MP0008569_lethality_at_weaning | 0.68208286 |
140 | MP0001944_abnormal_pancreas_morphology | 0.67783057 |
141 | MP0005620_abnormal_muscle_contractility | 0.67644186 |
142 | MP0001186_pigmentation_phenotype | 0.67606560 |
143 | MP0000003_abnormal_adipose_tissue | 0.67361815 |
144 | MP0002736_abnormal_nociception_after | 0.66744343 |
145 | MP0001879_abnormal_lymphatic_vessel | 0.65850874 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Absent/shortened dynein arms (HP:0200106) | 4.03094160 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.03094160 |
3 | Hypothermia (HP:0002045) | 4.02366731 |
4 | White forelock (HP:0002211) | 3.98288108 |
5 | Abnormal hair whorl (HP:0010721) | 3.90097822 |
6 | Patchy hypopigmentation of hair (HP:0011365) | 3.87507661 |
7 | Hyperventilation (HP:0002883) | 3.36474247 |
8 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.29596137 |
9 | Medial flaring of the eyebrow (HP:0010747) | 3.02476222 |
10 | Subaortic stenosis (HP:0001682) | 2.90626647 |
11 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.90626647 |
12 | Congenital sensorineural hearing impairment (HP:0008527) | 2.90372700 |
13 | Absent speech (HP:0001344) | 2.84520900 |
14 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.83071543 |
15 | Genetic anticipation (HP:0003743) | 2.80302271 |
16 | Chromsome breakage (HP:0040012) | 2.78456037 |
17 | Abnormality of the right ventricle (HP:0001707) | 2.76455199 |
18 | True hermaphroditism (HP:0010459) | 2.75408745 |
19 | Papillary thyroid carcinoma (HP:0002895) | 2.74305496 |
20 | Exercise-induced myalgia (HP:0003738) | 2.69828666 |
21 | Muscle fiber inclusion bodies (HP:0100299) | 2.66429790 |
22 | Renal cortical cysts (HP:0000803) | 2.65368588 |
23 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.64629408 |
24 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.64629408 |
25 | Decreased circulating renin level (HP:0003351) | 2.63890063 |
26 | Intestinal atresia (HP:0011100) | 2.61317795 |
27 | Hypoglycemic coma (HP:0001325) | 2.61144161 |
28 | Lip pit (HP:0100267) | 2.61084590 |
29 | Bell-shaped thorax (HP:0001591) | 2.60298267 |
30 | Nephrogenic diabetes insipidus (HP:0009806) | 2.60201599 |
31 | Abnormal ciliary motility (HP:0012262) | 2.57588261 |
32 | Volvulus (HP:0002580) | 2.56873196 |
33 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.54508306 |
34 | Nemaline bodies (HP:0003798) | 2.53606693 |
35 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.50011055 |
36 | Broad-based gait (HP:0002136) | 2.45915032 |
37 | Nephronophthisis (HP:0000090) | 2.45595729 |
38 | Gaze-evoked nystagmus (HP:0000640) | 2.43448473 |
39 | Abnormality of the corticospinal tract (HP:0002492) | 2.42416280 |
40 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.41612790 |
41 | Hypoplastic iliac wings (HP:0002866) | 2.41147161 |
42 | Neoplasm of the adrenal cortex (HP:0100641) | 2.40684889 |
43 | Molar tooth sign on MRI (HP:0002419) | 2.36957629 |
44 | Abnormality of midbrain morphology (HP:0002418) | 2.36957629 |
45 | Pancreatic fibrosis (HP:0100732) | 2.36645760 |
46 | Ketoacidosis (HP:0001993) | 2.36600161 |
47 | Retinal dysplasia (HP:0007973) | 2.34766290 |
48 | Exercise-induced muscle cramps (HP:0003710) | 2.34429077 |
49 | Febrile seizures (HP:0002373) | 2.33715093 |
50 | Amyotrophic lateral sclerosis (HP:0007354) | 2.32273716 |
51 | Thyroid carcinoma (HP:0002890) | 2.32236224 |
52 | Hypoplasia of the fovea (HP:0007750) | 2.31245342 |
53 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.31245342 |
54 | Hypoglycemic seizures (HP:0002173) | 2.31243140 |
55 | Truncal obesity (HP:0001956) | 2.28993116 |
56 | Abnormality of the renal collecting system (HP:0004742) | 2.28149090 |
57 | Osteomalacia (HP:0002749) | 2.27532217 |
58 | Abnormality of incisor morphology (HP:0011063) | 2.27157428 |
59 | Abnormality of the renal cortex (HP:0011035) | 2.26091260 |
60 | Drooling (HP:0002307) | 2.24814229 |
61 | Abnormality of the renal medulla (HP:0100957) | 2.18908307 |
62 | Atrial fibrillation (HP:0005110) | 2.16695034 |
63 | Alveolar cell carcinoma (HP:0006519) | 2.15736849 |
64 | Absent eyebrow (HP:0002223) | 2.15382796 |
65 | Abnormality of the calf musculature (HP:0001430) | 2.14802162 |
66 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.14651410 |
67 | Abnormality of the nasolacrimal system (HP:0000614) | 2.14238208 |
68 | Rimmed vacuoles (HP:0003805) | 2.13637158 |
69 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.13201701 |
70 | Atonic seizures (HP:0010819) | 2.12339166 |
71 | Submucous cleft hard palate (HP:0000176) | 2.12134312 |
72 | Congenital primary aphakia (HP:0007707) | 2.11713746 |
73 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.11518496 |
74 | Protruding tongue (HP:0010808) | 2.11442159 |
75 | Poor coordination (HP:0002370) | 2.10691283 |
76 | Excessive salivation (HP:0003781) | 2.08993190 |
77 | Median cleft lip (HP:0000161) | 2.08954659 |
78 | Gait imbalance (HP:0002141) | 2.08264069 |
79 | Conjugated hyperbilirubinemia (HP:0002908) | 2.08113229 |
80 | Pancreatic cysts (HP:0001737) | 2.07525809 |
81 | Papilledema (HP:0001085) | 2.07436982 |
82 | Prolonged QT interval (HP:0001657) | 2.07193898 |
83 | Hypoplastic ischia (HP:0003175) | 2.05777938 |
84 | Duplicated collecting system (HP:0000081) | 2.04254553 |
85 | Abnormality of the ischium (HP:0003174) | 2.04113697 |
86 | Aqueductal stenosis (HP:0002410) | 2.03310725 |
87 | Nasolacrimal duct obstruction (HP:0000579) | 2.02738611 |
88 | Abnormality of renal resorption (HP:0011038) | 2.02544323 |
89 | Ketosis (HP:0001946) | 2.02301199 |
90 | Metaphyseal dysplasia (HP:0100255) | 2.01450496 |
91 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.00285399 |
92 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.00285399 |
93 | Hyperkalemia (HP:0002153) | 1.98749809 |
94 | Methylmalonic acidemia (HP:0002912) | 1.97405006 |
95 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.97334143 |
96 | Abnormality of the fovea (HP:0000493) | 1.97095010 |
97 | Constricted visual fields (HP:0001133) | 1.96773418 |
98 | Calf muscle hypertrophy (HP:0008981) | 1.96589232 |
99 | Steppage gait (HP:0003376) | 1.94225542 |
100 | Congenital stationary night blindness (HP:0007642) | 1.94174372 |
101 | Menstrual irregularities (HP:0000858) | 1.94074350 |
102 | Long clavicles (HP:0000890) | 1.93912760 |
103 | Stomach cancer (HP:0012126) | 1.92377977 |
104 | Abnormality of the lacrimal duct (HP:0011481) | 1.92374274 |
105 | Attenuation of retinal blood vessels (HP:0007843) | 1.91655821 |
106 | Hyperglycemia (HP:0003074) | 1.91330310 |
107 | Hemiparesis (HP:0001269) | 1.90917075 |
108 | Myoglobinuria (HP:0002913) | 1.90657767 |
109 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.89542792 |
110 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.89542792 |
111 | Genital tract atresia (HP:0001827) | 1.88731012 |
112 | Keratoconus (HP:0000563) | 1.88572375 |
113 | Increased corneal curvature (HP:0100692) | 1.88572375 |
114 | Aplasia cutis congenita (HP:0001057) | 1.86150297 |
115 | Primary atrial arrhythmia (HP:0001692) | 1.85607716 |
116 | Tubulointerstitial nephritis (HP:0001970) | 1.85343479 |
117 | Cupped ear (HP:0000378) | 1.85020624 |
118 | EMG: neuropathic changes (HP:0003445) | 1.84464755 |
119 | Abnormality of vitamin B metabolism (HP:0004340) | 1.83612309 |
120 | Vaginal atresia (HP:0000148) | 1.83113233 |
121 | Facial diplegia (HP:0001349) | 1.82959116 |
122 | Thyroiditis (HP:0100646) | 1.82340047 |
123 | Epileptic encephalopathy (HP:0200134) | 1.81181576 |
124 | Prostate neoplasm (HP:0100787) | 1.80998328 |
125 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.79990482 |
126 | Tented upper lip vermilion (HP:0010804) | 1.79950929 |
127 | Optic nerve hypoplasia (HP:0000609) | 1.78900007 |
128 | Testicular neoplasm (HP:0010788) | 1.77361280 |
129 | Downturned corners of mouth (HP:0002714) | 1.75806803 |
130 | Hypomagnesemia (HP:0002917) | 1.75757107 |
131 | Renal tubular dysfunction (HP:0000124) | 1.75468209 |
132 | Left ventricular hypertrophy (HP:0001712) | 1.75389279 |
133 | Nephropathy (HP:0000112) | 1.75101137 |
134 | Central scotoma (HP:0000603) | 1.75049106 |
135 | Bundle branch block (HP:0011710) | 1.74960200 |
136 | Chronic hepatic failure (HP:0100626) | 1.74704162 |
137 | Bradycardia (HP:0001662) | 1.74499070 |
138 | Progressive cerebellar ataxia (HP:0002073) | 1.74098199 |
139 | Dyschromatopsia (HP:0007641) | 1.73856381 |
140 | Short foot (HP:0001773) | 1.73693227 |
141 | Azoospermia (HP:0000027) | 1.72202960 |
142 | Postaxial foot polydactyly (HP:0001830) | 1.71444112 |
143 | Dyskinesia (HP:0100660) | 1.70048809 |
144 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.69796316 |
145 | Renal Fanconi syndrome (HP:0001994) | 1.69202935 |
146 | Supraventricular tachycardia (HP:0004755) | 1.69057490 |
147 | Hypsarrhythmia (HP:0002521) | 1.68219409 |
148 | Prolonged bleeding time (HP:0003010) | 1.66957820 |
149 | Proximal tubulopathy (HP:0000114) | 1.66478578 |
150 | Blue irides (HP:0000635) | 1.65387031 |
151 | Agitation (HP:0000713) | 1.64576144 |
152 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.64413511 |
153 | Xerostomia (HP:0000217) | 1.63898126 |
154 | Type I transferrin isoform profile (HP:0003642) | 1.63890869 |
155 | EEG with generalized epileptiform discharges (HP:0011198) | 1.63747111 |
156 | Congenital hepatic fibrosis (HP:0002612) | 1.63276501 |
157 | Hyperphosphatemia (HP:0002905) | 1.61978479 |
158 | Macroorchidism (HP:0000053) | 1.61804121 |
159 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.61216955 |
160 | Abnormality of the nasal septum (HP:0000419) | 1.59998018 |
161 | Supraventricular arrhythmia (HP:0005115) | 1.57915918 |
162 | Type 2 muscle fiber atrophy (HP:0003554) | 1.57568221 |
163 | Aganglionic megacolon (HP:0002251) | 1.57244086 |
164 | Anteriorly placed anus (HP:0001545) | 1.57150670 |
165 | Abnormality of the columella (HP:0009929) | 1.57005466 |
166 | Symptomatic seizures (HP:0011145) | 1.56958745 |
167 | Widely spaced teeth (HP:0000687) | 1.55821843 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TNIK | 3.38157696 |
2 | CASK | 3.15079646 |
3 | INSRR | 2.67123154 |
4 | BMPR2 | 2.60677122 |
5 | ACVR1B | 2.56210985 |
6 | MAP3K4 | 2.40558376 |
7 | NUAK1 | 2.23578833 |
8 | MAP3K14 | 2.03044811 |
9 | ZAK | 2.02699830 |
10 | BMPR1B | 2.02691676 |
11 | MAP4K2 | 2.02269962 |
12 | IRAK4 | 2.01760886 |
13 | IRAK1 | 1.96542628 |
14 | MAPK15 | 1.89448409 |
15 | FGFR2 | 1.86134934 |
16 | TAOK3 | 1.81832990 |
17 | PIK3CG | 1.81142685 |
18 | OBSCN | 1.77878962 |
19 | BRD4 | 1.75235730 |
20 | MUSK | 1.73741332 |
21 | EPHA3 | 1.72944259 |
22 | AKT3 | 1.71865369 |
23 | NEK6 | 1.65900308 |
24 | MARK1 | 1.64562611 |
25 | YES1 | 1.62585362 |
26 | PIK3CA | 1.60653139 |
27 | SGK2 | 1.58641433 |
28 | SIK3 | 1.55177532 |
29 | PRKD3 | 1.51142040 |
30 | LMTK2 | 1.48052998 |
31 | STK39 | 1.41229837 |
32 | MYLK | 1.36424213 |
33 | WNK1 | 1.33807167 |
34 | CDK3 | 1.27569805 |
35 | PRPF4B | 1.27095515 |
36 | EIF2AK3 | 1.26381540 |
37 | CLK1 | 1.25222886 |
38 | HIPK2 | 1.25219301 |
39 | ERBB3 | 1.24560000 |
40 | NTRK3 | 1.22915388 |
41 | IRAK3 | 1.22658712 |
42 | STK24 | 1.20069913 |
43 | MAP3K7 | 1.18858859 |
44 | DMPK | 1.18154397 |
45 | SGK223 | 1.15861777 |
46 | SGK494 | 1.15861777 |
47 | PRKCE | 1.12774887 |
48 | MAP3K2 | 1.12245855 |
49 | PAK3 | 1.12080238 |
50 | CDC42BPA | 1.11260701 |
51 | MAPKAPK5 | 1.11026533 |
52 | STK16 | 1.10672023 |
53 | MAP2K4 | 1.10638583 |
54 | TRPM7 | 1.09279704 |
55 | TXK | 1.04470397 |
56 | MAPK13 | 1.03730241 |
57 | STK3 | 1.03299105 |
58 | FGFR3 | 1.02337650 |
59 | GRK7 | 1.02182960 |
60 | WNK4 | 1.01361123 |
61 | PNCK | 1.00024454 |
62 | FRK | 0.98284201 |
63 | TEC | 0.97835639 |
64 | RIPK4 | 0.93905657 |
65 | EIF2AK2 | 0.93344204 |
66 | WNK3 | 0.91411455 |
67 | NME1 | 0.87204227 |
68 | CAMKK2 | 0.86043718 |
69 | PTK2B | 0.85221261 |
70 | ADRBK2 | 0.83653867 |
71 | GRK1 | 0.83079278 |
72 | RPS6KA2 | 0.81904911 |
73 | SGK3 | 0.80761361 |
74 | RPS6KL1 | 0.80360400 |
75 | RPS6KC1 | 0.80360400 |
76 | DAPK2 | 0.80163094 |
77 | DYRK1A | 0.79841383 |
78 | MAP2K7 | 0.79723386 |
79 | TRIM28 | 0.78639183 |
80 | IRAK2 | 0.78424510 |
81 | BRSK2 | 0.78337677 |
82 | CAMK2D | 0.78268825 |
83 | PIM2 | 0.78162003 |
84 | CDK8 | 0.76296661 |
85 | NLK | 0.75116125 |
86 | PRKG2 | 0.74543556 |
87 | CSNK1G2 | 0.74116913 |
88 | KIT | 0.73637224 |
89 | BCR | 0.73634115 |
90 | RPS6KA6 | 0.72800084 |
91 | TIE1 | 0.68665583 |
92 | MAP3K12 | 0.67807439 |
93 | MAPK12 | 0.66329912 |
94 | FER | 0.62969456 |
95 | PLK2 | 0.62474680 |
96 | STK11 | 0.61270712 |
97 | TNK2 | 0.60846794 |
98 | PASK | 0.60079591 |
99 | PRKG1 | 0.60065819 |
100 | PRKAA1 | 0.58455513 |
101 | MAPK7 | 0.56226614 |
102 | CAMK2A | 0.55566679 |
103 | PKN1 | 0.54765194 |
104 | PRKCQ | 0.54196777 |
105 | PINK1 | 0.53962876 |
106 | CAMK1 | 0.53568570 |
107 | SGK1 | 0.53532691 |
108 | CAMK1G | 0.51661400 |
109 | CSNK1G1 | 0.50712855 |
110 | IKBKE | 0.50341194 |
111 | MKNK1 | 0.48298223 |
112 | NTRK2 | 0.48224919 |
113 | PRKAA2 | 0.47156573 |
114 | VRK1 | 0.46983453 |
115 | CDK19 | 0.46810424 |
116 | IKBKB | 0.46244509 |
117 | TGFBR2 | 0.46097806 |
118 | UHMK1 | 0.45809773 |
119 | NEK9 | 0.45508233 |
120 | PHKG2 | 0.44642900 |
121 | PHKG1 | 0.44642900 |
122 | MKNK2 | 0.44487854 |
123 | CAMK4 | 0.44267044 |
124 | CAMK2B | 0.44053018 |
125 | CHUK | 0.43827948 |
126 | MAP2K6 | 0.43766938 |
127 | OXSR1 | 0.43694830 |
128 | PRKACA | 0.43443425 |
129 | MARK3 | 0.43352105 |
130 | JAK3 | 0.43149363 |
131 | PRKCG | 0.42745913 |
132 | CSNK1G3 | 0.42407596 |
133 | RPS6KA5 | 0.41351162 |
134 | STK38L | 0.41076574 |
135 | MARK2 | 0.41034075 |
136 | RPS6KB1 | 0.39596205 |
137 | FLT3 | 0.39219194 |
138 | STK38 | 0.37785068 |
139 | CSNK1D | 0.37573746 |
140 | BTK | 0.37056793 |
141 | TGFBR1 | 0.36510750 |
142 | MAP3K6 | 0.35945662 |
143 | ADRBK1 | 0.34580708 |
144 | PDK3 | 0.32798320 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protein export_Homo sapiens_hsa03060 | 3.48079280 |
2 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.56381648 |
3 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.49143465 |
4 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.30634909 |
5 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.15073573 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.03737257 |
7 | Taste transduction_Homo sapiens_hsa04742 | 1.98841447 |
8 | Phototransduction_Homo sapiens_hsa04744 | 1.95031086 |
9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.90635280 |
10 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.87107094 |
11 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.84087096 |
12 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.62914849 |
13 | Insulin secretion_Homo sapiens_hsa04911 | 1.62480462 |
14 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.62008878 |
15 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.59819391 |
16 | Circadian entrainment_Homo sapiens_hsa04713 | 1.52210808 |
17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.48909816 |
18 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.48846769 |
19 | Morphine addiction_Homo sapiens_hsa05032 | 1.42613503 |
20 | Nicotine addiction_Homo sapiens_hsa05033 | 1.33781282 |
21 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.33634123 |
22 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.31971916 |
23 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.27195146 |
24 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.22477257 |
25 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.21455814 |
26 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.19636647 |
27 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.16546360 |
28 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.15358727 |
29 | Circadian rhythm_Homo sapiens_hsa04710 | 1.14771321 |
30 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.13860750 |
31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.13592564 |
32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.13586903 |
33 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.13250084 |
34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.10810567 |
35 | Platelet activation_Homo sapiens_hsa04611 | 1.09594688 |
36 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.08593279 |
37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.06116638 |
38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.03472244 |
39 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.03327977 |
40 | Alzheimers disease_Homo sapiens_hsa05010 | 1.01201109 |
41 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.00966817 |
42 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.00886364 |
43 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.00749399 |
44 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.98039959 |
45 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.94903221 |
46 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.93248903 |
47 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.90783973 |
48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90606432 |
49 | Renin secretion_Homo sapiens_hsa04924 | 0.89492145 |
50 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.88934825 |
51 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.88749422 |
52 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.87805887 |
53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.87668435 |
54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.87276892 |
55 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.87172023 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.86521103 |
57 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.85729491 |
58 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.85048245 |
59 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.83248671 |
60 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.82732928 |
61 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.81854796 |
62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.81791437 |
63 | GABAergic synapse_Homo sapiens_hsa04727 | 0.81328896 |
64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.80788938 |
65 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.79941699 |
66 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.79773811 |
67 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.79757602 |
68 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.79317760 |
69 | Insulin resistance_Homo sapiens_hsa04931 | 0.79127934 |
70 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.77170841 |
71 | Peroxisome_Homo sapiens_hsa04146 | 0.76878130 |
72 | Huntingtons disease_Homo sapiens_hsa05016 | 0.75523294 |
73 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.75364778 |
74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.74259731 |
75 | Lysine degradation_Homo sapiens_hsa00310 | 0.73890497 |
76 | Cocaine addiction_Homo sapiens_hsa05030 | 0.73601168 |
77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73139093 |
78 | ABC transporters_Homo sapiens_hsa02010 | 0.72892569 |
79 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.72777498 |
80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71009582 |
81 | Axon guidance_Homo sapiens_hsa04360 | 0.69462130 |
82 | Parkinsons disease_Homo sapiens_hsa05012 | 0.68997656 |
83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.68844513 |
84 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.68653089 |
85 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.68591657 |
86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.68131809 |
87 | Phagosome_Homo sapiens_hsa04145 | 0.68126110 |
88 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.67320553 |
89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.66145691 |
90 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.65071349 |
91 | Measles_Homo sapiens_hsa05162 | 0.64780558 |
92 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.64350819 |
93 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.64019815 |
94 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63964362 |
95 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62486838 |
96 | Mineral absorption_Homo sapiens_hsa04978 | 0.62174568 |
97 | Long-term potentiation_Homo sapiens_hsa04720 | 0.61477297 |
98 | Basal transcription factors_Homo sapiens_hsa03022 | 0.60169369 |
99 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.60100509 |
100 | Salivary secretion_Homo sapiens_hsa04970 | 0.59340719 |
101 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.59056089 |
102 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.58700745 |
103 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.58672475 |
104 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.58644703 |
105 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.58551951 |
106 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.58540890 |
107 | RNA degradation_Homo sapiens_hsa03018 | 0.58462051 |
108 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.58287709 |
109 | Long-term depression_Homo sapiens_hsa04730 | 0.57862460 |
110 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.55387614 |
111 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.54814093 |
112 | Other glycan degradation_Homo sapiens_hsa00511 | 0.54584621 |
113 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.53905112 |
114 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.53661994 |
115 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.53059725 |
116 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.52766009 |
117 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.51895147 |
118 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.51002489 |
119 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.50945325 |
120 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.50457934 |
121 | Gap junction_Homo sapiens_hsa04540 | 0.49415025 |
122 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.48736868 |
123 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.48598476 |
124 | Leishmaniasis_Homo sapiens_hsa05140 | 0.47278458 |
125 | Melanoma_Homo sapiens_hsa05218 | 0.47218523 |
126 | Purine metabolism_Homo sapiens_hsa00230 | 0.46951985 |
127 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.46737833 |
128 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.46009948 |
129 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.45459211 |
130 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.45173999 |
131 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.44513766 |
132 | Malaria_Homo sapiens_hsa05144 | 0.44471386 |
133 | Histidine metabolism_Homo sapiens_hsa00340 | 0.44235697 |
134 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.44202873 |
135 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.43521134 |
136 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41856635 |
137 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.41490991 |
138 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.41429507 |
139 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.41217409 |
140 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40966714 |
141 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40914967 |
142 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.38283941 |
143 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.37001171 |