RELL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)7.03826104
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.66658901
3locomotory exploration behavior (GO:0035641)6.23914969
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.84612293
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.84236529
6synaptic vesicle exocytosis (GO:0016079)5.73458404
7glutamate secretion (GO:0014047)5.73112520
8synaptic vesicle docking involved in exocytosis (GO:0016081)5.52410281
9regulation of synaptic vesicle exocytosis (GO:2000300)5.51350619
10vocalization behavior (GO:0071625)5.47127489
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.36233090
12neuronal action potential propagation (GO:0019227)5.05879149
13regulation of glutamate receptor signaling pathway (GO:1900449)5.00932675
14neurotransmitter secretion (GO:0007269)5.00017687
15regulation of synaptic vesicle transport (GO:1902803)4.92539994
16protein localization to synapse (GO:0035418)4.88354762
17exploration behavior (GO:0035640)4.85082553
18regulation of neuronal synaptic plasticity (GO:0048168)4.76981896
19regulation of long-term neuronal synaptic plasticity (GO:0048169)4.65178397
20layer formation in cerebral cortex (GO:0021819)4.62912918
21ionotropic glutamate receptor signaling pathway (GO:0035235)4.53730935
22regulation of synapse structural plasticity (GO:0051823)4.52008474
23gamma-aminobutyric acid transport (GO:0015812)4.30689145
24sodium ion export (GO:0071436)4.21784980
25cellular potassium ion homeostasis (GO:0030007)4.21548226
26proline transport (GO:0015824)4.20567406
27neuron cell-cell adhesion (GO:0007158)4.16600385
28synaptic transmission, glutamatergic (GO:0035249)4.14333199
29negative regulation of erythrocyte differentiation (GO:0045647)4.11700281
30dendritic spine morphogenesis (GO:0060997)4.11449805
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.07425688
32neuromuscular process controlling posture (GO:0050884)4.00917878
33neurotransmitter-gated ion channel clustering (GO:0072578)4.00354035
34neurotransmitter transport (GO:0006836)3.95505941
35positive regulation of membrane potential (GO:0045838)3.95078589
36activation of protein kinase A activity (GO:0034199)3.93927318
37glycine transport (GO:0015816)3.93498629
38glutamate receptor signaling pathway (GO:0007215)3.91355482
39long-term memory (GO:0007616)3.90922615
40neuron-neuron synaptic transmission (GO:0007270)3.87410871
41regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.87277875
42neuromuscular process controlling balance (GO:0050885)3.83301582
43cerebellar granule cell differentiation (GO:0021707)3.78580872
44regulation of excitatory postsynaptic membrane potential (GO:0060079)3.73802623
45positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.70372055
46cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.70189778
47regulation of neurotransmitter levels (GO:0001505)3.69113864
48regulation of neurotransmitter secretion (GO:0046928)3.63669892
49establishment of mitochondrion localization (GO:0051654)3.63079491
50regulation of synaptic plasticity (GO:0048167)3.62494511
51cerebellar Purkinje cell differentiation (GO:0021702)3.61801834
52signal complex assembly (GO:0007172)3.61318135
53positive regulation of synaptic transmission, GABAergic (GO:0032230)3.54356090
54regulation of postsynaptic membrane potential (GO:0060078)3.53619269
55cell communication by electrical coupling (GO:0010644)3.52481594
56regulation of dendritic spine morphogenesis (GO:0061001)3.50743616
57synaptic vesicle endocytosis (GO:0048488)3.46981659
58regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.45710866
59transmission of nerve impulse (GO:0019226)3.43794331
60auditory behavior (GO:0031223)3.42167427
61response to auditory stimulus (GO:0010996)3.42149945
62positive regulation of neurotransmitter transport (GO:0051590)3.38050862
63positive regulation of synapse maturation (GO:0090129)3.38021578
64regulation of neurotransmitter transport (GO:0051588)3.37919379
65regulation of vesicle fusion (GO:0031338)3.37425105
66regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.36426231
67regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.36142062
68G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.35586748
69positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.35409926
70prepulse inhibition (GO:0060134)3.35364850
71protein localization to endosome (GO:0036010)3.33317285
72positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.31694182
73positive regulation of neurotransmitter secretion (GO:0001956)3.30419057
74membrane depolarization during action potential (GO:0086010)3.30235164
75negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.29824670
76regulation of ARF protein signal transduction (GO:0032012)3.27659815
77dendrite morphogenesis (GO:0048813)3.27364358
78vesicle transport along microtubule (GO:0047496)3.26550138
79neuronal ion channel clustering (GO:0045161)3.24775960
80long-term synaptic potentiation (GO:0060291)3.23722887
81neuron recognition (GO:0008038)3.22716226
82modulation by virus of host process (GO:0019054)3.21777136
83postsynaptic membrane organization (GO:0001941)3.21735267
84mitochondrion transport along microtubule (GO:0047497)3.21579737
85establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.21579737
86peptidyl-arginine omega-N-methylation (GO:0035247)3.19592542
87amino acid import (GO:0043090)3.19030327
88cell migration in hindbrain (GO:0021535)3.18607512
89regulation of defense response to virus by virus (GO:0050690)3.18319621
90neuromuscular process (GO:0050905)3.17600724
91regulation of synaptic transmission, glutamatergic (GO:0051966)3.16833566
92regulation of chromatin binding (GO:0035561)3.16640322
93membrane depolarization (GO:0051899)3.15584483
94membrane hyperpolarization (GO:0060081)3.14912865
95positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.14504323
96cytoskeletal anchoring at plasma membrane (GO:0007016)3.14034427
97axon cargo transport (GO:0008088)3.13026750
98negative regulation of synaptic transmission, GABAergic (GO:0032229)3.11094908
99L-amino acid import (GO:0043092)3.10069599
100regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.06810710
101adult walking behavior (GO:0007628)3.03962989
102regulation of synaptic transmission (GO:0050804)3.03516233
103dendritic spine organization (GO:0097061)3.03181219
104positive regulation of dendritic spine development (GO:0060999)3.02960515
105positive regulation of synaptic transmission (GO:0050806)3.02859092
106synaptic transmission (GO:0007268)3.02476518
107negative regulation of microtubule polymerization (GO:0031115)3.02296671
108gamma-aminobutyric acid signaling pathway (GO:0007214)3.01914300
109organelle transport along microtubule (GO:0072384)3.01617807
110learning (GO:0007612)3.01496528
111regulation of voltage-gated calcium channel activity (GO:1901385)3.00935075
112potassium ion import (GO:0010107)2.99678668
113intraspecies interaction between organisms (GO:0051703)2.99279467
114social behavior (GO:0035176)2.99279467
115regulation of mammary gland epithelial cell proliferation (GO:0033599)2.98960806
116calcium ion-dependent exocytosis (GO:0017156)2.97005536
117innervation (GO:0060384)2.96950163
118positive regulation of protein dephosphorylation (GO:0035307)2.96877050
119negative regulation of cell killing (GO:0031342)2.95076721
120negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.95076721
121intracellular estrogen receptor signaling pathway (GO:0030520)2.94927998
122peptidyl-tyrosine autophosphorylation (GO:0038083)2.94537302
123regulation of regulated secretory pathway (GO:1903305)2.90792307
124positive regulation of gamma-delta T cell activation (GO:0046645)2.90638635
125regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.87517535
126positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.87517535
127thymic T cell selection (GO:0045061)2.87037068
128regulation of ARF GTPase activity (GO:0032312)2.80337214
129glucose 6-phosphate metabolic process (GO:0051156)2.79076183
130positive regulation of Rap GTPase activity (GO:0032854)2.78911387
131regulation of synapse maturation (GO:0090128)2.76868170
132activation of Rac GTPase activity (GO:0032863)2.76669885
133regulation of NFAT protein import into nucleus (GO:0051532)2.67382143
134peptidyl-arginine methylation (GO:0018216)2.67091365
135peptidyl-arginine N-methylation (GO:0035246)2.67091365
136mannose metabolic process (GO:0006013)2.66649652
137regulation of early endosome to late endosome transport (GO:2000641)2.65602285
138modulation by symbiont of host cellular process (GO:0044068)2.64496724
139retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.62188196
140positive regulation of dendritic spine morphogenesis (GO:0061003)2.57878972
141dopamine receptor signaling pathway (GO:0007212)2.52701145
142negative regulation of phagocytosis (GO:0050765)2.51603983
143T cell selection (GO:0045058)2.51141055
144establishment of synaptic vesicle localization (GO:0097480)2.50916402
145synaptic vesicle transport (GO:0048489)2.50916402
146regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.48263661
147dicarboxylic acid transport (GO:0006835)2.48041132
148detection of temperature stimulus involved in sensory perception (GO:0050961)2.47529454
149detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.47529454
150vesicle docking involved in exocytosis (GO:0006904)2.47026438
151positive regulation of histone acetylation (GO:0035066)2.46623401
152protein insertion into membrane (GO:0051205)2.46212574
153adenosine receptor signaling pathway (GO:0001973)2.46004247

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.09415544
2SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.20099897
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.16601785
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.10188325
5* REST_21632747_ChIP-Seq_MESCs_Mouse3.03408945
6RARB_27405468_Chip-Seq_BRAIN_Mouse3.03274439
7MYC_22102868_ChIP-Seq_BL_Human2.94578739
8GBX2_23144817_ChIP-Seq_PC3_Human2.89395102
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.85499347
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.85499347
11VDR_21846776_ChIP-Seq_THP-1_Human2.84322282
12DROSHA_22980978_ChIP-Seq_HELA_Human2.83263869
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.79888900
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.72060137
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.69019658
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.56838360
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.56490152
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.55572465
19IKZF1_21737484_ChIP-ChIP_HCT116_Human2.53600943
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50219651
21EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.50170247
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.48861376
23EZH2_27304074_Chip-Seq_ESCs_Mouse2.46981506
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.46680823
25EZH2_27294783_Chip-Seq_ESCs_Mouse2.43232594
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.33561317
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.28574386
28RNF2_27304074_Chip-Seq_ESCs_Mouse2.27577528
29KDM2B_26808549_Chip-Seq_DND41_Human2.27258903
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.21471651
31EED_16625203_ChIP-ChIP_MESCs_Mouse2.10098946
32TCF7_22412390_ChIP-Seq_EML_Mouse2.07972117
33TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05543958
34ELK3_25401928_ChIP-Seq_HUVEC_Human2.04894656
35P68_20966046_ChIP-Seq_HELA_Human1.96498711
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.94361952
37TET1_21451524_ChIP-Seq_MESCs_Mouse1.90261129
38AR_21572438_ChIP-Seq_LNCaP_Human1.89087740
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.86306901
40ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83272621
41SRY_22984422_ChIP-ChIP_TESTIS_Rat1.80166900
42RACK7_27058665_Chip-Seq_MCF-7_Human1.79027464
43NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.77872830
44* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.72881626
45EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.70155181
46HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.67957302
47CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.67760574
48CTCF_27219007_Chip-Seq_ERYTHROID_Human1.66438632
49KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.65054052
50DNAJC2_21179169_ChIP-ChIP_NT2_Human1.62453568
51ELF1_20517297_ChIP-Seq_JURKAT_Human1.60980092
52MAF_26560356_Chip-Seq_TH2_Human1.59438175
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.59348030
54SA1_27219007_Chip-Seq_ERYTHROID_Human1.59062709
55* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.54774890
56* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.54565035
57ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.53440751
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.52136527
59MAF_26560356_Chip-Seq_TH1_Human1.50522757
60UTX_26944678_Chip-Seq_JUKART_Human1.49869272
61KDM2B_26808549_Chip-Seq_K562_Human1.49453888
62CREB1_26743006_Chip-Seq_LNCaP_Human1.45349087
63DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.45165636
64CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.45037242
65ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.44699684
66ZFP281_18757296_ChIP-ChIP_E14_Mouse1.44055415
67CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.43311864
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.43016779
69RING1B_27294783_Chip-Seq_ESCs_Mouse1.41107862
70* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.40906201
71SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39724890
72CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38379552
73SMAD4_21799915_ChIP-Seq_A2780_Human1.38086368
74VDR_24763502_ChIP-Seq_THP-1_Human1.37856584
75EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.37136143
76RUNX1_22412390_ChIP-Seq_EML_Mouse1.36131645
77BCOR_27268052_Chip-Seq_Bcells_Human1.35913784
78SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.34298018
79THAP11_20581084_ChIP-Seq_MESCs_Mouse1.33745789
80BCL6_27268052_Chip-Seq_Bcells_Human1.31040452
81TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.29516657
82ZNF274_21170338_ChIP-Seq_K562_Hela1.29155749
83CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.28331324
84UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.28219733
85WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24048155
86MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.23752569
87NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23751099
88CTBP1_25329375_ChIP-Seq_LNCAP_Human1.22793667
89PU.1_20513432_ChIP-Seq_Bcells_Mouse1.22291583
90* NCOR1_26117541_ChIP-Seq_K562_Human1.21994155
91MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.21885671
92GATA1_19941827_ChIP-Seq_MEL_Mouse1.21434765
93SOX2_21211035_ChIP-Seq_LN229_Gbm1.21315128
94WT1_25993318_ChIP-Seq_PODOCYTE_Human1.20900846
95AR_19668381_ChIP-Seq_PC3_Human1.20622886
96TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.18200178
97MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.18060318
98KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17768182
99SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.17338889
100GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16723864
101SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.16707070
102PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.16624962
103SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15467972
104GATA1_22383799_ChIP-Seq_G1ME_Mouse1.15460712
105RARA_24833708_ChIP-Seq_LIVER_Mouse1.15007145
106SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14962872
107CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.14087591
108PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13183757
109KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12724006
110RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.12657303
111PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12162739
112PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.11943649
113STAT6_21828071_ChIP-Seq_BEAS2B_Human1.11912526
114RING1B_27294783_Chip-Seq_NPCs_Mouse1.11280289
115PHF8_20622854_ChIP-Seq_HELA_Human1.10402759
116TAF15_26573619_Chip-Seq_HEK293_Human1.10374177
117CIITA_25753668_ChIP-Seq_RAJI_Human1.10172167
118ETS1_21867929_ChIP-Seq_TH2_Mouse1.07882810
119RARB_24833708_ChIP-Seq_LIVER_Mouse1.07870974
120AR_25329375_ChIP-Seq_VCAP_Human1.07243494
121SA1_27219007_Chip-Seq_Bcells_Human1.07236759
122SMAD_19615063_ChIP-ChIP_OVARY_Human1.07123661
123ZNF263_19887448_ChIP-Seq_K562_Human1.06659530
124TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.06544693
125TET1_21490601_ChIP-Seq_MESCs_Mouse1.05421725
126E2F1_20622854_ChIP-Seq_HELA_Human1.04834434
127P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04021106
128CTCF_26484167_Chip-Seq_Bcells_Mouse1.03230972
129CTCF_27219007_Chip-Seq_Bcells_Human1.03112274
130TP63_17297297_ChIP-ChIP_HaCaT_Human1.03100484
131KDM2B_26808549_Chip-Seq_SUP-B15_Human1.03030710
132RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.02449245
133STAT3_23295773_ChIP-Seq_U87_Human1.02073117
134* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.01730277
135SPI1_23127762_ChIP-Seq_K562_Human1.01368409
136SMAD3_21741376_ChIP-Seq_EPCs_Human0.98365400
137SMAD3_21741376_ChIP-Seq_ESCs_Human0.95970791
138MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95511910
139THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95291660
140P300_19829295_ChIP-Seq_ESCs_Human0.95090749
141YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93566992
142TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92573758
143VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90524269
144TOP2B_26459242_ChIP-Seq_MCF-7_Human0.88912401
145TCF4_23295773_ChIP-Seq_U87_Human0.87500818
146RNF2_27304074_Chip-Seq_NSC_Mouse0.86856075
147ZNF217_24962896_ChIP-Seq_MCF-7_Human0.86264696
148SMAD4_21741376_ChIP-Seq_HESCs_Human0.86241324
149SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85015232
150BMI1_23680149_ChIP-Seq_NPCS_Mouse0.84327885
151OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.84169403
152AHR_22903824_ChIP-Seq_MCF-7_Human0.84103888
153KLF4_19829295_ChIP-Seq_ESCs_Human0.83440883
154ARNT_22903824_ChIP-Seq_MCF-7_Human0.83389059
155IGF1R_20145208_ChIP-Seq_DFB_Human0.83075898
156OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.82914160
157DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.82191849
158LXR_22292898_ChIP-Seq_THP-1_Human0.81879892
159CDX2_19796622_ChIP-Seq_MESCs_Mouse0.81431489
160SMC4_20622854_ChIP-Seq_HELA_Human0.81041979
161CBX2_27304074_Chip-Seq_ESCs_Mouse0.80698153
162SMAD3_21741376_ChIP-Seq_HESCs_Human0.80511645
163RXR_22108803_ChIP-Seq_LS180_Human0.80502639
164SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79997079
165PRDM14_20953172_ChIP-Seq_ESCs_Human0.79806940
166ZFP57_27257070_Chip-Seq_ESCs_Mouse0.79101311
167OCT4_19829295_ChIP-Seq_ESCs_Human0.77499274
168KDM2B_26808549_Chip-Seq_JURKAT_Human0.77273608

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.07694969
2MP0003880_abnormal_central_pattern4.63313333
3MP0003635_abnormal_synaptic_transmissio4.35456567
4MP0004270_analgesia4.01842730
5MP0009745_abnormal_behavioral_response3.48646983
6MP0002063_abnormal_learning/memory/cond3.36931826
7MP0009046_muscle_twitch3.27951125
8MP0002064_seizures3.26583488
9MP0001968_abnormal_touch/_nociception3.19886027
10MP0005423_abnormal_somatic_nervous3.07379700
11MP0002822_catalepsy2.87045298
12MP0002734_abnormal_mechanical_nocicepti2.80910125
13MP0002272_abnormal_nervous_system2.74290880
14MP0002572_abnormal_emotion/affect_behav2.73348246
15MP0001486_abnormal_startle_reflex2.63060294
16MP0008260_abnormal_autophagy2.60294783
17MP0002736_abnormal_nociception_after2.39796042
18MP0002735_abnormal_chemical_nociception2.36845991
19MP0001501_abnormal_sleep_pattern2.31885476
20MP0002733_abnormal_thermal_nociception2.26047827
21MP0008569_lethality_at_weaning2.24382483
22MP0001970_abnormal_pain_threshold2.13118628
23MP0004858_abnormal_nervous_system2.12421550
24MP0004811_abnormal_neuron_physiology2.00846243
25MP0002067_abnormal_sensory_capabilities1.99493175
26MP0001440_abnormal_grooming_behavior1.98729708
27MP0003329_amyloid_beta_deposits1.96852499
28MP0005451_abnormal_body_composition1.94376111
29MP0002909_abnormal_adrenal_gland1.87205166
30MP0003705_abnormal_hypodermis_morpholog1.85085380
31MP0002184_abnormal_innervation1.83784695
32MP0009780_abnormal_chondrocyte_physiolo1.82686742
33MP0002557_abnormal_social/conspecific_i1.77056431
34MP0004924_abnormal_behavior1.75486047
35MP0005386_behavior/neurological_phenoty1.75486047
36MP0009278_abnormal_bone_marrow1.75090673
37MP0000955_abnormal_spinal_cord1.74736829
38MP0005464_abnormal_platelet_physiology1.72804015
39MP0000678_abnormal_parathyroid_gland1.71293887
40MP0003436_decreased_susceptibility_to1.70777000
41MP0003123_paternal_imprinting1.69711231
42MP0005058_abnormal_lysosome_morphology1.69443397
43MP0003303_peritoneal_inflammation1.68558853
44MP0000778_abnormal_nervous_system1.65577319
45MP0003763_abnormal_thymus_physiology1.63868136
46MP0006276_abnormal_autonomic_nervous1.62611063
47MP0003879_abnormal_hair_cell1.60678705
48MP0004885_abnormal_endolymph1.58854072
49MP0003633_abnormal_nervous_system1.50148224
50MP0004142_abnormal_muscle_tone1.49250162
51MP0002066_abnormal_motor_capabilities/c1.48253782
52MP0002882_abnormal_neuron_morphology1.45256476
53MP0005646_abnormal_pituitary_gland1.44621591
54MP0003787_abnormal_imprinting1.34704661
55MP0001873_stomach_inflammation1.33405370
56MP0001984_abnormal_olfaction1.30974220
57MP0005310_abnormal_salivary_gland1.28308590
58MP0004947_skin_inflammation1.26881006
59MP0004185_abnormal_adipocyte_glucose1.25273647
60MP0003631_nervous_system_phenotype1.24749840
61MP0001849_ear_inflammation1.23855435
62MP0005645_abnormal_hypothalamus_physiol1.23105101
63MP0005076_abnormal_cell_differentiation1.21392225
64MP0001502_abnormal_circadian_rhythm1.19592393
65MP0001905_abnormal_dopamine_level1.17344401
66MP0005671_abnormal_response_to1.12835665
67MP0009333_abnormal_splenocyte_physiolog1.12778905
68MP0000703_abnormal_thymus_morphology1.11503067
69MP0005000_abnormal_immune_tolerance1.10660739
70MP0000569_abnormal_digit_pigmentation1.08960532
71MP0002152_abnormal_brain_morphology1.08383879
72MP0008872_abnormal_physiological_respon1.06880623
73MP0003191_abnormal_cellular_cholesterol1.06649588
74MP0001529_abnormal_vocalization1.06160111
75MP0002229_neurodegeneration1.06139409
76MP0002398_abnormal_bone_marrow1.05761910
77MP0003075_altered_response_to1.05654539
78MP0003122_maternal_imprinting1.05328572
79MP0000751_myopathy1.02669179
80MP0002089_abnormal_postnatal_growth/wei1.01723909
81MP0008961_abnormal_basal_metabolism0.99090691
82MP0008874_decreased_physiological_sensi0.98609871
83MP0003690_abnormal_glial_cell0.96322944
84MP0001188_hyperpigmentation0.96072423
85MP0009672_abnormal_birth_weight0.95180136
86MP0000920_abnormal_myelination0.94896511
87MP0002069_abnormal_eating/drinking_beha0.93613334
88MP0003634_abnormal_glial_cell0.90775961
89MP0000604_amyloidosis0.90718548
90MP0005025_abnormal_response_to0.90260244
91MP0002420_abnormal_adaptive_immunity0.89309126
92MP0004145_abnormal_muscle_electrophysio0.87058023
93MP0005083_abnormal_biliary_tract0.86945794
94MP0001819_abnormal_immune_cell0.86421197
95MP0003632_abnormal_nervous_system0.85880757
96MP0000013_abnormal_adipose_tissue0.85123398
97MP0003283_abnormal_digestive_organ0.85097529
98MP0001177_atelectasis0.83663815
99MP0009840_abnormal_foam_cell0.82065304
100MP0002723_abnormal_immune_serum0.81928232
101MP0005167_abnormal_blood-brain_barrier0.81578334
102MP0001346_abnormal_lacrimal_gland0.81554010
103MP0000716_abnormal_immune_system0.81229745
104MP0002653_abnormal_ependyma_morphology0.80609521
105MP0000858_altered_metastatic_potential0.79941871
106MP0002722_abnormal_immune_system0.79420160
107MP0005535_abnormal_body_temperature0.79193301
108MP0001800_abnormal_humoral_immune0.78017336
109MP0002249_abnormal_larynx_morphology0.77221019
110MP0004742_abnormal_vestibular_system0.77209824
111MP0005499_abnormal_olfactory_system0.75795658
112MP0005394_taste/olfaction_phenotype0.75795658
113MP0002419_abnormal_innate_immunity0.75419392
114MP0000490_abnormal_crypts_of0.75307476
115MP0004085_abnormal_heartbeat0.74951590
116MP0001963_abnormal_hearing_physiology0.74003390
117MP0003172_abnormal_lysosome_physiology0.73749925
118MP0004381_abnormal_hair_follicle0.73454736
119MP0001790_abnormal_immune_system0.73388713
120MP0005387_immune_system_phenotype0.73388713
121MP0002796_impaired_skin_barrier0.73233197
122MP0005501_abnormal_skin_physiology0.72834609
123MP0002429_abnormal_blood_cell0.72597881
124MP0002752_abnormal_somatic_nervous0.71402473
125MP0005551_abnormal_eye_electrophysiolog0.68964362
126MP0006035_abnormal_mitochondrial_morpho0.68381906
127MP0000685_abnormal_immune_system0.68146431
128MP0001348_abnormal_lacrimal_gland0.66567848
129MP0002090_abnormal_vision0.65666995
130MP0003137_abnormal_impulse_conducting0.62471218
131MP0004510_myositis0.60775458
132MP0005623_abnormal_meninges_morphology0.60564301
133MP0000631_abnormal_neuroendocrine_gland0.57647063
134MP0010769_abnormal_survival0.56789978
135MP0010234_abnormal_vibrissa_follicle0.56099191
136MP0001664_abnormal_digestion0.54697512
137MP0001943_abnormal_respiration0.54374066
138MP0002638_abnormal_pupillary_reflex0.54218148
139MP0010768_mortality/aging0.53234813
140MP0003956_abnormal_body_size0.53207082
141MP0010770_preweaning_lethality0.53011624
142MP0002082_postnatal_lethality0.53011624
143MP0001485_abnormal_pinna_reflex0.52475245
144MP0005409_darkened_coat_color0.52113169
145MP0000747_muscle_weakness0.51913041
146MP0003861_abnormal_nervous_system0.50992486
147MP0010386_abnormal_urinary_bladder0.50913549
148MP0004233_abnormal_muscle_weight0.50685403

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)8.03407498
2Focal motor seizures (HP:0011153)7.07071219
3Visual hallucinations (HP:0002367)5.61113189
4Focal seizures (HP:0007359)5.60624772
5Action tremor (HP:0002345)4.53873819
6Atonic seizures (HP:0010819)4.52386818
7Supranuclear gaze palsy (HP:0000605)4.51493758
8Febrile seizures (HP:0002373)4.47733626
9Epileptic encephalopathy (HP:0200134)4.46947563
10Progressive cerebellar ataxia (HP:0002073)4.40948314
11Ankle clonus (HP:0011448)4.26169615
12Absence seizures (HP:0002121)3.99442355
13Generalized tonic-clonic seizures (HP:0002069)3.72263040
14Dialeptic seizures (HP:0011146)3.61355891
15Cholecystitis (HP:0001082)3.60862494
16Abnormal gallbladder physiology (HP:0012438)3.60862494
17Mutism (HP:0002300)3.60046648
18Depression (HP:0000716)3.56443059
19Impaired vibration sensation in the lower limbs (HP:0002166)3.56356600
20Papilledema (HP:0001085)3.53567814
21Urinary bladder sphincter dysfunction (HP:0002839)3.52988715
22Poor eye contact (HP:0000817)3.42929888
23Postural instability (HP:0002172)3.36048738
24Gaze-evoked nystagmus (HP:0000640)3.32005009
25Broad-based gait (HP:0002136)3.21673925
26Truncal ataxia (HP:0002078)3.21344396
27Peripheral hypomyelination (HP:0007182)3.21067275
28Abnormal eating behavior (HP:0100738)3.17467413
29Urinary urgency (HP:0000012)3.16861629
30Dysmetria (HP:0001310)3.16452973
31Dysdiadochokinesis (HP:0002075)3.15386202
32Anxiety (HP:0000739)3.14883691
33Abnormal social behavior (HP:0012433)3.10307454
34Impaired social interactions (HP:0000735)3.10307454
35Torticollis (HP:0000473)3.04144017
36Abnormality of the lower motor neuron (HP:0002366)3.03519598
37Ventricular fibrillation (HP:0001663)3.00863388
38Spastic gait (HP:0002064)2.95227988
39Reticulocytosis (HP:0001923)2.91857998
40Hyperacusis (HP:0010780)2.90384319
41Hemiplegia (HP:0002301)2.86852471
42Intention tremor (HP:0002080)2.85223092
43Scanning speech (HP:0002168)2.85200959
44Genetic anticipation (HP:0003743)2.84271453
45Annular pancreas (HP:0001734)2.81706046
46Focal dystonia (HP:0004373)2.80428496
47Impaired smooth pursuit (HP:0007772)2.76879964
48Progressive inability to walk (HP:0002505)2.76501619
49Obstructive lung disease (HP:0006536)2.71488997
50Chronic obstructive pulmonary disease (HP:0006510)2.71488997
51Amblyopia (HP:0000646)2.69557238
52Bradykinesia (HP:0002067)2.69179634
53Hyperthyroidism (HP:0000836)2.67409864
54Upper limb amyotrophy (HP:0009129)2.67045546
55Distal upper limb amyotrophy (HP:0007149)2.67045546
56J-shaped sella turcica (HP:0002680)2.62718408
57Megalencephaly (HP:0001355)2.60393886
58Hemiparesis (HP:0001269)2.58725256
59Insomnia (HP:0100785)2.58307856
60Fetal akinesia sequence (HP:0001989)2.55745978
61Craniofacial dystonia (HP:0012179)2.55342913
62Hand muscle atrophy (HP:0009130)2.51161880
63Stereotypic behavior (HP:0000733)2.50291476
64Diplopia (HP:0000651)2.49795347
65Abnormality of binocular vision (HP:0011514)2.49795347
66Truncus arteriosus (HP:0001660)2.47235027
67Abnormality of the corticospinal tract (HP:0002492)2.44249957
68Pointed chin (HP:0000307)2.41471748
69Bundle branch block (HP:0011710)2.41107507
70Lower limb muscle weakness (HP:0007340)2.40987070
71Cerebral hypomyelination (HP:0006808)2.40287336
72Broad face (HP:0000283)2.39467440
73Abnormality of ocular smooth pursuit (HP:0000617)2.39399088
74Pheochromocytoma (HP:0002666)2.38789097
75Limb dystonia (HP:0002451)2.37113969
76Impaired vibratory sensation (HP:0002495)2.37053554
77Slow saccadic eye movements (HP:0000514)2.35437375
78Status epilepticus (HP:0002133)2.35304906
79Bowel incontinence (HP:0002607)2.34556066
80Termporal pattern (HP:0011008)2.33312002
81Insidious onset (HP:0003587)2.33312002
82Long palpebral fissure (HP:0000637)2.32083927
83Tetraplegia (HP:0002445)2.31125743
84Neurofibrillary tangles (HP:0002185)2.30302527
85Drooling (HP:0002307)2.30258236
86Excessive salivation (HP:0003781)2.30258236
87Clonus (HP:0002169)2.26752072
88Dysmetric saccades (HP:0000641)2.25017382
89Abnormal large intestine physiology (HP:0012700)2.25001380
90Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.18275644
91Distal lower limb amyotrophy (HP:0008944)2.18252600
92Petechiae (HP:0000967)2.17756000
93Agitation (HP:0000713)2.15639368
94Cerebral inclusion bodies (HP:0100314)2.14552271
95Prolonged bleeding time (HP:0003010)2.11976247
96Neuroendocrine neoplasm (HP:0100634)2.10949918
97Epileptiform EEG discharges (HP:0011182)2.10772910
98Eczematoid dermatitis (HP:0000976)2.10653761
99Amyotrophic lateral sclerosis (HP:0007354)2.09690101
100EEG with generalized epileptiform discharges (HP:0011198)2.08424420
101Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.07834889
102Apathy (HP:0000741)2.07279588
103Polyphagia (HP:0002591)2.06598226
104Abnormality of macrophages (HP:0004311)2.06522977
105Abnormality of saccadic eye movements (HP:0000570)2.06325167
106Hyperventilation (HP:0002883)2.06260161
107Athetosis (HP:0002305)2.05026077
108Gastrointestinal inflammation (HP:0004386)2.04903443
109Hypsarrhythmia (HP:0002521)2.04499086
110Abnormal EKG (HP:0003115)2.04117688
111Obstructive sleep apnea (HP:0002870)2.03416691
112Neuronal loss in central nervous system (HP:0002529)2.02701980
113Rigidity (HP:0002063)2.02163832
114Purpura (HP:0000979)2.01931829
115Delusions (HP:0000746)1.97208959
116Neoplasm of the peripheral nervous system (HP:0100007)1.96961619
117Incomplete penetrance (HP:0003829)1.96324937
118Generalized myoclonic seizures (HP:0002123)1.94603354
119Absent speech (HP:0001344)1.93400362
120Rapidly progressive (HP:0003678)1.93037006
121Inability to walk (HP:0002540)1.92538388
122Gait ataxia (HP:0002066)1.92147324
123Achilles tendon contracture (HP:0001771)1.91967630
124Upper limb muscle weakness (HP:0003484)1.90914119
125Spinal canal stenosis (HP:0003416)1.90044859
126Personality changes (HP:0000751)1.89887971
127Psychosis (HP:0000709)1.89878620
128Lower limb asymmetry (HP:0100559)1.86824360
129Distal sensory impairment (HP:0002936)1.86706319
130Increased cerebral lipofuscin (HP:0011813)1.85652991
131Cholelithiasis (HP:0001081)1.85275007
132Lower limb amyotrophy (HP:0007210)1.85222875
133Recurrent bacterial skin infections (HP:0005406)1.84438949
134Hypertensive crisis (HP:0100735)1.83972598
135Akinesia (HP:0002304)1.83802667
136Cellulitis (HP:0100658)1.83743623
137Resting tremor (HP:0002322)1.83657955
138Failure to thrive in infancy (HP:0001531)1.83136297
139Diminished motivation (HP:0000745)1.82860231
140Seborrheic dermatitis (HP:0001051)1.78580105
141Recurrent abscess formation (HP:0002722)1.76733128
142Deep palmar crease (HP:0006191)1.76475220
143Abnormal platelet volume (HP:0011876)1.75482896
144Abnormal platelet function (HP:0011869)1.74867402
145Impaired platelet aggregation (HP:0003540)1.74867402
146Growth hormone excess (HP:0000845)1.72295607
147Limb ataxia (HP:0002070)1.71717874
148Abnormality of the Achilles tendon (HP:0005109)1.70694404
149Global brain atrophy (HP:0002283)1.70594675
150Thin bony cortex (HP:0002753)1.70462541
151Hypercortisolism (HP:0001578)1.70324357
152Upper motor neuron abnormality (HP:0002127)1.70317852

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K94.38252672
2NTRK34.18729746
3EPHA43.67449388
4TRIB33.61609212
5MARK13.34349571
6MINK13.05483552
7MAP3K42.90160523
8DAPK22.68170466
9MAP2K72.48020517
10PAK62.42085937
11KSR22.33277749
12PRKD32.26790390
13CAMKK12.24742950
14SMG12.20793927
15NTRK22.08331522
16MAP4K12.05583201
17NTRK11.92139345
18ERN11.89236791
19MAP2K41.86457752
20MAP3K121.86203063
21CDK191.84805132
22ICK1.83633578
23TESK21.79814500
24SIK11.74966953
25MAP3K101.65233826
26MAPK131.63347236
27DAPK11.59751940
28CDK51.59601653
29MAP3K111.58844790
30STK381.57343716
31GRK51.48669393
32TAOK11.48566659
33PKN21.44811985
34RIPK41.43369185
35TNIK1.42530387
36TESK11.42272837
37BRAF1.41661550
38KSR11.37891847
39MAP3K21.36788434
40UHMK11.36399863
41IRAK31.34443849
42SIK31.33837358
43ARAF1.32749093
44PIM21.23339891
45CAMKK21.22803491
46PRKCG1.21881333
47CDK121.21548792
48PHKG11.21163968
49PHKG21.21163968
50FES1.19770980
51TYRO31.18714146
52SIK21.17834314
53PLK21.15625452
54LMTK21.14225950
55MAP3K131.11701744
56MAP2K31.11426135
57LATS21.10891527
58PRKD21.07686826
59ALK1.03454153
60TAOK21.03372048
61PRKCH1.01215626
62CAMK10.99512058
63PINK10.99350349
64GRK60.98388370
65IRAK20.98361359
66RET0.96575980
67STK110.95843624
68FGFR40.94314653
69PRPF4B0.94207500
70SGK2230.90582767
71SGK4940.90582767
72IRAK40.90438350
73CDK180.89053374
74CDK150.88952085
75SCYL20.85946337
76CDK140.85560154
77CASK0.85257155
78PNCK0.84971193
79CDK11A0.82603431
80MARK20.81116149
81RAF10.77316994
82BMX0.77007526
83TNK20.76680290
84CAMK1D0.75973386
85EEF2K0.75730838
86PDK10.75046938
87CAMK2A0.74401015
88BTK0.73250315
89CSNK1G20.73208991
90BRSK10.70924029
91ZAP700.70110650
92MAPKAPK50.69655353
93NEK10.69272635
94SGK20.68810547
95SGK30.67642684
96MAP3K10.65694596
97WNK10.65662508
98SYK0.63607770
99PDPK10.63607759
100RIPK10.61863159
101BLK0.60443311
102PRKCI0.60152494
103PAK30.59179561
104RPS6KA20.58848837
105FGR0.57652465
106MAPKAPK30.56981375
107OXSR10.55622541
108CAMK2B0.53613693
109CDC42BPA0.53254997
110MAPK110.52774360
111HCK0.52708668
112DYRK1A0.52692344
113KDR0.52672223
114RPS6KL10.51794615
115RPS6KC10.51794615
116SGK10.51357297
117LIMK10.51034128
118PTK60.50122326
119PRKG20.48930322
120DYRK1B0.48085673
121PRKCZ0.47876258
122TYK20.47459274
123RPS6KA30.46842454
124CSF1R0.46371543
125DAPK30.44119775
126NME20.43952068
127CAMK2G0.43870540
128CSK0.43700656
129CAMK40.42240390
130CAMK1G0.41596574
131ITK0.41356177
132JAK20.41188409
133MTOR0.40863804
134MAPK100.40704747
135FYN0.39849111
136MAPK120.39778448
137MAP2K60.38777414
138NEK60.38291475
139EPHB10.38133375
140MAP3K70.37647590
141PTK2B0.36331383
142MAP2K10.34390251
143CCNB10.31611810
144BMPR20.31383500
145MUSK0.30359947
146PRKCE0.28852407
147PRKCB0.26952033

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.56789989
2Nicotine addiction_Homo sapiens_hsa050333.36123460
3Olfactory transduction_Homo sapiens_hsa047402.95382893
4Circadian entrainment_Homo sapiens_hsa047132.68434770
5GABAergic synapse_Homo sapiens_hsa047272.67102767
6Long-term potentiation_Homo sapiens_hsa047202.58509355
7Glutamatergic synapse_Homo sapiens_hsa047242.53181190
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.49491083
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.48173354
10Morphine addiction_Homo sapiens_hsa050322.43048204
11Amphetamine addiction_Homo sapiens_hsa050312.34222142
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.28420667
13Dopaminergic synapse_Homo sapiens_hsa047282.18633413
14Salivary secretion_Homo sapiens_hsa049702.13617544
15Cholinergic synapse_Homo sapiens_hsa047252.00987176
16Insulin secretion_Homo sapiens_hsa049111.99453090
17Gastric acid secretion_Homo sapiens_hsa049711.98837824
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.86095100
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.80243759
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.73849259
21Oxytocin signaling pathway_Homo sapiens_hsa049211.63398156
22Long-term depression_Homo sapiens_hsa047301.62371005
23Cocaine addiction_Homo sapiens_hsa050301.61020846
24Taste transduction_Homo sapiens_hsa047421.58456853
25Renin secretion_Homo sapiens_hsa049241.54317470
26B cell receptor signaling pathway_Homo sapiens_hsa046621.51153050
27GnRH signaling pathway_Homo sapiens_hsa049121.49652222
28Acute myeloid leukemia_Homo sapiens_hsa052211.49056467
29Nitrogen metabolism_Homo sapiens_hsa009101.47998233
30Serotonergic synapse_Homo sapiens_hsa047261.47463674
31Calcium signaling pathway_Homo sapiens_hsa040201.44782065
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.38424855
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.37222194
34Gap junction_Homo sapiens_hsa045401.36958121
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.36384922
36cAMP signaling pathway_Homo sapiens_hsa040241.24593059
37Glioma_Homo sapiens_hsa052141.22769474
38T cell receptor signaling pathway_Homo sapiens_hsa046601.22762992
39Collecting duct acid secretion_Homo sapiens_hsa049661.19199005
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17812670
41Type II diabetes mellitus_Homo sapiens_hsa049301.16958260
42Estrogen signaling pathway_Homo sapiens_hsa049151.16781172
43Other glycan degradation_Homo sapiens_hsa005111.14930042
44Chronic myeloid leukemia_Homo sapiens_hsa052201.14394477
45Shigellosis_Homo sapiens_hsa051311.10117457
46ErbB signaling pathway_Homo sapiens_hsa040121.08589335
47Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.06337451
48Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.05390479
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.04521960
50Melanogenesis_Homo sapiens_hsa049161.01478383
51Axon guidance_Homo sapiens_hsa043601.00212692
52Osteoclast differentiation_Homo sapiens_hsa043800.96145238
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.94636829
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94230733
55Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.93873770
56Oocyte meiosis_Homo sapiens_hsa041140.93289730
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92936326
58Pancreatic cancer_Homo sapiens_hsa052120.91039173
59Phospholipase D signaling pathway_Homo sapiens_hsa040720.89800636
60Sulfur relay system_Homo sapiens_hsa041220.89713757
61Cardiac muscle contraction_Homo sapiens_hsa042600.87582616
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87566286
63Notch signaling pathway_Homo sapiens_hsa043300.87261219
64Dorso-ventral axis formation_Homo sapiens_hsa043200.86508856
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.85265223
66Vascular smooth muscle contraction_Homo sapiens_hsa042700.81992110
67Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80590747
68Thyroid hormone synthesis_Homo sapiens_hsa049180.79606283
69Vibrio cholerae infection_Homo sapiens_hsa051100.79339223
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78509750
71Pancreatic secretion_Homo sapiens_hsa049720.78271430
72Salmonella infection_Homo sapiens_hsa051320.73457522
73MAPK signaling pathway_Homo sapiens_hsa040100.72255183
74Fructose and mannose metabolism_Homo sapiens_hsa000510.72039008
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71664908
76VEGF signaling pathway_Homo sapiens_hsa043700.71142172
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.71120769
78Tuberculosis_Homo sapiens_hsa051520.70413340
79Biosynthesis of amino acids_Homo sapiens_hsa012300.69947270
802-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.69839619
81Pentose phosphate pathway_Homo sapiens_hsa000300.69769373
82Phototransduction_Homo sapiens_hsa047440.68753835
83Choline metabolism in cancer_Homo sapiens_hsa052310.68463095
84AMPK signaling pathway_Homo sapiens_hsa041520.65933252
85Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65135066
86Endocytosis_Homo sapiens_hsa041440.62622367
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.62368860
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.61687969
89Vitamin B6 metabolism_Homo sapiens_hsa007500.60225444
90Hepatitis B_Homo sapiens_hsa051610.59410372
91HIF-1 signaling pathway_Homo sapiens_hsa040660.58992782
92Dilated cardiomyopathy_Homo sapiens_hsa054140.58908606
93Ras signaling pathway_Homo sapiens_hsa040140.58415031
94Bladder cancer_Homo sapiens_hsa052190.58304991
95SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57397856
96Endometrial cancer_Homo sapiens_hsa052130.57383293
97Bile secretion_Homo sapiens_hsa049760.56791337
98Rap1 signaling pathway_Homo sapiens_hsa040150.56204232
99mTOR signaling pathway_Homo sapiens_hsa041500.55955848
100Non-small cell lung cancer_Homo sapiens_hsa052230.55576716
101Glucagon signaling pathway_Homo sapiens_hsa049220.54860310
102Inositol phosphate metabolism_Homo sapiens_hsa005620.54098466
103Alcoholism_Homo sapiens_hsa050340.53794592
104Glycosaminoglycan degradation_Homo sapiens_hsa005310.53754774
105Leukocyte transendothelial migration_Homo sapiens_hsa046700.53609326
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.53179572
107Type I diabetes mellitus_Homo sapiens_hsa049400.52413453
108Thyroid cancer_Homo sapiens_hsa052160.51668775
109Apoptosis_Homo sapiens_hsa042100.51667157
110Primary immunodeficiency_Homo sapiens_hsa053400.51547319
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49710312
112Insulin signaling pathway_Homo sapiens_hsa049100.49346615
113Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49207912
114Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.47411018
115Prion diseases_Homo sapiens_hsa050200.45784180
116Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44965770
117Chemokine signaling pathway_Homo sapiens_hsa040620.43207434
118Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42925696
119Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42357814
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41031895
121Renal cell carcinoma_Homo sapiens_hsa052110.39267491
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39090695
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38493983
124Prolactin signaling pathway_Homo sapiens_hsa049170.34081070
125Colorectal cancer_Homo sapiens_hsa052100.33309598
126Wnt signaling pathway_Homo sapiens_hsa043100.33097671
127Circadian rhythm_Homo sapiens_hsa047100.32699720
128Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32151926
129Central carbon metabolism in cancer_Homo sapiens_hsa052300.31826015
130Platelet activation_Homo sapiens_hsa046110.31098615
131Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.29578324
132Ovarian steroidogenesis_Homo sapiens_hsa049130.29246777

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