REM2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)5.05093759
2dendritic spine morphogenesis (GO:0060997)5.05048011
3auditory behavior (GO:0031223)4.88126709
4regulation of synapse structural plasticity (GO:0051823)4.87483542
5pyrimidine nucleobase catabolic process (GO:0006208)4.84173555
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.52072867
7regulation of short-term neuronal synaptic plasticity (GO:0048172)4.47127066
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.42121441
9synaptic vesicle maturation (GO:0016188)4.40173335
10regulation of synaptic vesicle exocytosis (GO:2000300)4.23833133
11vocalization behavior (GO:0071625)4.19204580
12mechanosensory behavior (GO:0007638)4.10400816
13negative regulation of microtubule polymerization (GO:0031115)4.09488888
14positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.07883500
15activated T cell proliferation (GO:0050798)4.05881777
16response to pheromone (GO:0019236)4.05420702
17prepulse inhibition (GO:0060134)4.04957240
18cell migration in hindbrain (GO:0021535)4.04644853
19response to auditory stimulus (GO:0010996)4.04299510
20neutrophil mediated immunity (GO:0002446)4.01829700
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.97718843
22synaptic vesicle exocytosis (GO:0016079)3.97095252
23dopamine receptor signaling pathway (GO:0007212)3.94425256
24regulation of glutamate receptor signaling pathway (GO:1900449)3.93725443
25regulation of synaptic vesicle transport (GO:1902803)3.90932882
26axonal fasciculation (GO:0007413)3.85428052
27locomotory exploration behavior (GO:0035641)3.82233778
28neuron recognition (GO:0008038)3.81455481
29protein localization to synapse (GO:0035418)3.80591686
30neuron cell-cell adhesion (GO:0007158)3.80510544
31regulation of neuronal synaptic plasticity (GO:0048168)3.69252036
32nucleobase catabolic process (GO:0046113)3.68817223
33dendritic spine organization (GO:0097061)3.67794057
34striatum development (GO:0021756)3.65683294
35positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.62564313
36mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.62564313
37layer formation in cerebral cortex (GO:0021819)3.61562587
38positive regulation of mitochondrial fission (GO:0090141)3.60826257
39regulation of long-term neuronal synaptic plasticity (GO:0048169)3.60504055
40positive regulation of synaptic transmission, GABAergic (GO:0032230)3.58698413
41protein polyglutamylation (GO:0018095)3.58278932
42substrate-independent telencephalic tangential migration (GO:0021826)3.57415197
43substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.57415197
44exploration behavior (GO:0035640)3.56376135
45modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.55856768
46modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.55856768
47positive regulation by organism of defense response of other organism involved in symbiotic interact3.55856768
48modulation by symbiont of host immune response (GO:0052553)3.55856768
49positive regulation by symbiont of host defense response (GO:0052509)3.55856768
50modulation by symbiont of host defense response (GO:0052031)3.55856768
51antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.53614581
52central nervous system projection neuron axonogenesis (GO:0021952)3.51113909
53synaptic transmission, dopaminergic (GO:0001963)3.49196405
54regulation of glutamate secretion (GO:0014048)3.47319808
55membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.45538620
56neurotransmitter secretion (GO:0007269)3.42975007
57acrosome reaction (GO:0007340)3.41556078
58G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.39961283
59positive regulation of protein homooligomerization (GO:0032464)3.38889394
60glutamate secretion (GO:0014047)3.38877094
61response to amphetamine (GO:0001975)3.37703577
62protein localization to cilium (GO:0061512)3.35719046
63synaptic vesicle docking involved in exocytosis (GO:0016081)3.32514299
64myeloid leukocyte mediated immunity (GO:0002444)3.31643577
65dendrite morphogenesis (GO:0048813)3.29942579
66negative regulation of cell killing (GO:0031342)3.29184727
67negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.29184727
68neurofilament cytoskeleton organization (GO:0060052)3.26789723
69leukocyte migration involved in inflammatory response (GO:0002523)3.18826603
70ionotropic glutamate receptor signaling pathway (GO:0035235)3.15955604
71negative regulation of dendrite development (GO:2000171)3.15923510
72neuronal action potential propagation (GO:0019227)3.15093420
73regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.14489743
74sequestering of actin monomers (GO:0042989)3.12841211
75neurotransmitter-gated ion channel clustering (GO:0072578)3.12023302
76respiratory burst (GO:0045730)3.09879826
77synaptic transmission, glutamatergic (GO:0035249)3.06080333
78cerebellar Purkinje cell differentiation (GO:0021702)3.02755727
79neuron-neuron synaptic transmission (GO:0007270)3.01050612
80behavioral response to nicotine (GO:0035095)3.00272724
81negative regulation of Rho protein signal transduction (GO:0035024)2.98676591
82positive regulation of synapse assembly (GO:0051965)2.98415407
83glial cell proliferation (GO:0014009)2.98319068
84regulation of dopamine metabolic process (GO:0042053)2.98117328
85regulation of catecholamine metabolic process (GO:0042069)2.98117328
86establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.97202043
87mitochondrion transport along microtubule (GO:0047497)2.97202043
88regulation of cilium movement (GO:0003352)2.95591682
89neuromuscular process controlling balance (GO:0050885)2.94273084
90regulation of synaptic transmission, GABAergic (GO:0032228)2.93577071
91positive regulation of synapse maturation (GO:0090129)2.93117998
92positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.92332362
93righting reflex (GO:0060013)2.91331252
94regulation of dendritic spine morphogenesis (GO:0061001)2.90001447
95transmission of nerve impulse (GO:0019226)2.89316122
96mating behavior (GO:0007617)2.87695689
97neuronal action potential (GO:0019228)2.87017474
98cerebellum development (GO:0021549)2.86415168
99regulation of synapse organization (GO:0050807)2.86351662
100dendrite development (GO:0016358)2.86310794
101synapse assembly (GO:0007416)2.85404608
102neuronal ion channel clustering (GO:0045161)2.84720704
103positive regulation of amino acid transport (GO:0051957)2.84146104
104negative regulation of synaptic transmission, GABAergic (GO:0032229)2.84141404
105postsynaptic membrane organization (GO:0001941)2.82659355
106retinal ganglion cell axon guidance (GO:0031290)2.82534904
107positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.81619794
108regulation of excitatory postsynaptic membrane potential (GO:0060079)2.80634037
109learning (GO:0007612)2.80365877
110innervation (GO:0060384)2.80180927
111behavioral response to cocaine (GO:0048148)2.79946043
112visual learning (GO:0008542)2.79464384
113regulation of synapse assembly (GO:0051963)2.79216377
114regulation of vesicle fusion (GO:0031338)2.77441406
115neural tube formation (GO:0001841)2.76769922
116calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.75793359
117regulation of synaptic plasticity (GO:0048167)2.75454964
118glutamate receptor signaling pathway (GO:0007215)2.75146878
119regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.74509566
120forebrain neuron differentiation (GO:0021879)2.74475159
121neutrophil activation (GO:0042119)2.74435509
122negative regulation of cAMP-mediated signaling (GO:0043951)2.74266422
123membrane depolarization during action potential (GO:0086010)2.73963323
124protein targeting to Golgi (GO:0000042)2.73956381
125protein insertion into membrane (GO:0051205)2.73671662
126macrophage activation involved in immune response (GO:0002281)2.73276174
127positive regulation of membrane potential (GO:0045838)2.73200959
128negative regulation of lymphocyte mediated immunity (GO:0002707)2.72879804
129long-term memory (GO:0007616)2.70960307
130olfactory bulb development (GO:0021772)2.70473362
131establishment of mitochondrion localization (GO:0051654)2.69904438
132neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.69728879
133regulation of postsynaptic membrane potential (GO:0060078)2.69530150
134visual behavior (GO:0007632)2.69244873
135negative regulation of dendrite morphogenesis (GO:0050774)2.69057697
136membrane hyperpolarization (GO:0060081)2.67327682
137behavioral defense response (GO:0002209)2.66350352
138establishment of protein localization to Golgi (GO:0072600)2.65044535
139adult walking behavior (GO:0007628)2.63817018
140positive regulation of release of cytochrome c from mitochondria (GO:0090200)2.62417003
141seminiferous tubule development (GO:0072520)2.61450850
142regulation of mitochondrial fission (GO:0090140)2.60552229
143negative regulation of immunoglobulin mediated immune response (GO:0002890)2.58556762
144negative regulation of B cell mediated immunity (GO:0002713)2.58556762
145epithelial cilium movement (GO:0003351)2.58428400
146negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.57152720
147regulation of T-helper 2 cell differentiation (GO:0045628)2.53482320
148regulation of collateral sprouting (GO:0048670)2.52659226
149synaptic transmission, cholinergic (GO:0007271)2.52448826
150glycosphingolipid biosynthetic process (GO:0006688)2.51719025
151response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.50952651
152response to host immune response (GO:0052572)2.50952651
153nonmotile primary cilium assembly (GO:0035058)2.48300648
154microtubule severing (GO:0051013)2.47783678
155phagosome maturation (GO:0090382)2.46800923
156interferon-gamma production (GO:0032609)2.44976315
157regulation of interferon-beta biosynthetic process (GO:0045357)2.44949419
158regulation of feeding behavior (GO:0060259)2.44027846
159sialylation (GO:0097503)2.43572216
160retrograde transport, vesicle recycling within Golgi (GO:0000301)2.41172306
161viral protein processing (GO:0019082)2.39961730
162gamma-aminobutyric acid transport (GO:0015812)2.39583452
163RNA destabilization (GO:0050779)2.39130969
164sperm motility (GO:0030317)2.38871180
165presynaptic membrane organization (GO:0097090)2.37166420
166negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.36902150
167regulation of microtubule-based movement (GO:0060632)2.35329144
168negative regulation of telomere maintenance (GO:0032205)2.34762991
169cell differentiation in spinal cord (GO:0021515)2.33997893
170positive regulation of oligodendrocyte differentiation (GO:0048714)2.33704519
171spinal cord association neuron differentiation (GO:0021527)2.33420147
172head development (GO:0060322)2.33386349
173disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.33052159

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.44854106
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.12780553
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.03382846
4EZH2_27304074_Chip-Seq_ESCs_Mouse3.03261449
5GBX2_23144817_ChIP-Seq_PC3_Human3.00889883
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.96634724
7JARID2_20075857_ChIP-Seq_MESCs_Mouse2.90898391
8CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.82474096
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.77434061
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.77434061
11* RARB_27405468_Chip-Seq_BRAIN_Mouse2.75947805
12REST_21632747_ChIP-Seq_MESCs_Mouse2.71950623
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.66527139
14* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.61015278
15* EZH2_27294783_Chip-Seq_ESCs_Mouse2.58006581
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.54905162
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.46169844
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.43148175
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.41858178
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.36148213
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35868064
22MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25951770
23MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.23308210
24EED_16625203_ChIP-ChIP_MESCs_Mouse2.20508882
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.07355654
26DROSHA_22980978_ChIP-Seq_HELA_Human1.98532572
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.94794952
28BMI1_23680149_ChIP-Seq_NPCS_Mouse1.87322937
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.87169925
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.83643290
31RNF2_27304074_Chip-Seq_NSC_Mouse1.80782133
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.77006874
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72942119
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.68812002
35OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.67501576
36* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.67118075
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66645170
38ERG_21242973_ChIP-ChIP_JURKAT_Human1.66131085
39* RING1B_27294783_Chip-Seq_ESCs_Mouse1.61071689
40IRF1_19129219_ChIP-ChIP_H3396_Human1.56947104
41ETV2_25802403_ChIP-Seq_MESCs_Mouse1.55851392
42RING1B_27294783_Chip-Seq_NPCs_Mouse1.50871037
43BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.50072054
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49168871
45RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.48974724
46ZNF274_21170338_ChIP-Seq_K562_Hela1.44313733
47IRF8_21731497_ChIP-ChIP_J774_Mouse1.41614142
48RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.38261382
49RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34494427
50DNAJC2_21179169_ChIP-ChIP_NT2_Human1.32443105
51AR_21572438_ChIP-Seq_LNCaP_Human1.29022576
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.27457957
53ERA_21632823_ChIP-Seq_H3396_Human1.26287735
54* KDM2B_26808549_Chip-Seq_K562_Human1.23590382
55WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.23265988
56BCL6_27268052_Chip-Seq_Bcells_Human1.23209090
57MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.20310418
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19725419
59IGF1R_20145208_ChIP-Seq_DFB_Human1.18079733
60TP53_20018659_ChIP-ChIP_R1E_Mouse1.18008260
61SMAD4_21799915_ChIP-Seq_A2780_Human1.17847926
62SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.17170598
63BP1_19119308_ChIP-ChIP_Hs578T_Human1.16905203
64CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.15685257
65VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.15281925
66ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.14402082
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.13912548
68TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13704336
69P300_19829295_ChIP-Seq_ESCs_Human1.13628701
70POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12849635
71EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.12007331
72TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.10991476
73NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10732604
74TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09780576
75TAF15_26573619_Chip-Seq_HEK293_Human1.09749002
76SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08775082
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.08105986
78GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06985304
79P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06883226
80NANOG_20526341_ChIP-Seq_ESCs_Human1.05743366
81WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05741261
82AR_19668381_ChIP-Seq_PC3_Human1.05461332
83OCT4_19829295_ChIP-Seq_ESCs_Human1.05111739
84RAC3_21632823_ChIP-Seq_H3396_Human1.05055233
85TP53_22573176_ChIP-Seq_HFKS_Human1.04034166
86CIITA_25753668_ChIP-Seq_RAJI_Human1.03154988
87STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.02955568
88EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.02534156
89MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.02026877
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02005587
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02005587
92HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.01974980
93UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01584531
94AHR_22903824_ChIP-Seq_MCF-7_Human1.00697116
95SMAD3_21741376_ChIP-Seq_ESCs_Human1.00523251
96FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99871036
97ZFP281_27345836_Chip-Seq_ESCs_Mouse0.99779862
98YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99673539
99CTCF_27219007_Chip-Seq_Bcells_Human0.99566930
100YY1_22570637_ChIP-Seq_MALME-3M_Human0.99333356
101RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98382927
102* NCOR_22424771_ChIP-Seq_293T_Human0.98321037
103RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.97007195
104ER_23166858_ChIP-Seq_MCF-7_Human0.96766419
105ZNF217_24962896_ChIP-Seq_MCF-7_Human0.96464498
106SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.96258483
107ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.95719300
108KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.95637582
109NR3C1_21868756_ChIP-Seq_MCF10A_Human0.94609369
110ELK4_26923725_Chip-Seq_MESODERM_Mouse0.94591913
111OCT4_20526341_ChIP-Seq_ESCs_Human0.93443189
112DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93073259
113OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92866110
114TET1_21490601_ChIP-Seq_MESCs_Mouse0.92824401
115WDR5_24793694_ChIP-Seq_LNCAP_Human0.92604394
116EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.92319371
117STAT3_23295773_ChIP-Seq_U87_Human0.91664657
118TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91514515
119CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.91471605
120GATA1_26923725_Chip-Seq_HPCs_Mouse0.91309609
121ARNT_22903824_ChIP-Seq_MCF-7_Human0.91290367
122PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.90952165
123MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.90370043
124FUS_26573619_Chip-Seq_HEK293_Human0.90020384
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89860491
126MYC_19829295_ChIP-Seq_ESCs_Human0.89429487
127CBP_20019798_ChIP-Seq_JUKART_Human0.89320012
128IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89320012
129PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.89246934
130PHF8_20622854_ChIP-Seq_HELA_Human0.88654637
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88322798
132E2F1_20622854_ChIP-Seq_HELA_Human0.88301268
133RUNX2_22187159_ChIP-Seq_PCA_Human0.87525807
134SMAD4_21741376_ChIP-Seq_HESCs_Human0.87232444
135AR_25329375_ChIP-Seq_VCAP_Human0.86620506
136LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.86225576
137GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.85759203
138ELF1_20517297_ChIP-Seq_JURKAT_Human0.84230953
139CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.83686106
140NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.82125020
141EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.82033344
142CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82003393
143TAF2_19829295_ChIP-Seq_ESCs_Human0.81927197
144PRDM14_20953172_ChIP-Seq_ESCs_Human0.78783647
145FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.78725205
146TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.78550362
147POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.78546550
148TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.77952185
149RUNX_20019798_ChIP-Seq_JUKART_Human0.77891405
150STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.77885120
151SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.77150910

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.90349438
2MP0003880_abnormal_central_pattern4.31164827
3MP0002822_catalepsy3.98081032
4MP0003635_abnormal_synaptic_transmissio3.23971979
5MP0001529_abnormal_vocalization3.21405151
6MP0003724_increased_susceptibility_to3.17420625
7MP0006276_abnormal_autonomic_nervous3.13809520
8MP0004270_analgesia3.04459849
9MP0002063_abnormal_learning/memory/cond3.00989082
10MP0009745_abnormal_behavioral_response2.63659875
11MP0003122_maternal_imprinting2.56530192
12MP0000778_abnormal_nervous_system2.56482643
13MP0005423_abnormal_somatic_nervous2.51953684
14MP0002572_abnormal_emotion/affect_behav2.41886927
15MP0001486_abnormal_startle_reflex2.26168661
16MP0002909_abnormal_adrenal_gland2.24330383
17MP0002734_abnormal_mechanical_nocicepti2.23801549
18MP0005645_abnormal_hypothalamus_physiol2.20614793
19MP0002184_abnormal_innervation2.17350645
20MP0002064_seizures2.15087803
21MP0001968_abnormal_touch/_nociception2.06010683
22MP0002735_abnormal_chemical_nociception2.03025210
23MP0001986_abnormal_taste_sensitivity1.97687557
24MP0002557_abnormal_social/conspecific_i1.95340403
25MP0004811_abnormal_neuron_physiology1.92823933
26MP0002733_abnormal_thermal_nociception1.91435022
27MP0002272_abnormal_nervous_system1.89640499
28MP0002638_abnormal_pupillary_reflex1.87438877
29MP0005499_abnormal_olfactory_system1.83932110
30MP0005394_taste/olfaction_phenotype1.83932110
31MP0008877_abnormal_DNA_methylation1.82271362
32MP0001984_abnormal_olfaction1.79724524
33MP0001970_abnormal_pain_threshold1.79313307
34MP0004924_abnormal_behavior1.77755164
35MP0005386_behavior/neurological_phenoty1.77755164
36MP0010386_abnormal_urinary_bladder1.70937692
37MP0001188_hyperpigmentation1.69699333
38MP0000955_abnormal_spinal_cord1.65279211
39MP0009046_muscle_twitch1.64020604
40MP0008789_abnormal_olfactory_epithelium1.60388618
41MP0008995_early_reproductive_senescence1.56330659
42MP0008260_abnormal_autophagy1.55157520
43MP0003787_abnormal_imprinting1.50833086
44MP0002751_abnormal_autonomic_nervous1.48365037
45MP0002067_abnormal_sensory_capabilities1.47279296
46MP0001440_abnormal_grooming_behavior1.45372531
47MP0003221_abnormal_cardiomyocyte_apopto1.44399298
48MP0000537_abnormal_urethra_morphology1.44287669
49MP0002928_abnormal_bile_duct1.43223326
50MP0000631_abnormal_neuroendocrine_gland1.41414303
51MP0002736_abnormal_nociception_after1.40271289
52MP0002882_abnormal_neuron_morphology1.40143687
53MP0005646_abnormal_pituitary_gland1.39396587
54MP0008961_abnormal_basal_metabolism1.39052444
55MP0001905_abnormal_dopamine_level1.35524670
56MP0003121_genomic_imprinting1.32762619
57MP0004858_abnormal_nervous_system1.32650919
58MP0005377_hearing/vestibular/ear_phenot1.30780616
59MP0003878_abnormal_ear_physiology1.30780616
60MP0002132_abnormal_respiratory_system1.29103140
61MP0003303_peritoneal_inflammation1.27251502
62MP0008569_lethality_at_weaning1.25802514
63MP0001502_abnormal_circadian_rhythm1.25375660
64MP0003436_decreased_susceptibility_to1.24935615
65MP0009780_abnormal_chondrocyte_physiolo1.24379410
66MP0002152_abnormal_brain_morphology1.23482360
67MP0002066_abnormal_motor_capabilities/c1.22329936
68MP0002234_abnormal_pharynx_morphology1.20042100
69MP0000013_abnormal_adipose_tissue1.18765755
70MP0003283_abnormal_digestive_organ1.17755421
71MP0005084_abnormal_gallbladder_morpholo1.15316109
72MP0002277_abnormal_respiratory_mucosa1.13446717
73MP0003329_amyloid_beta_deposits1.13271818
74MP0003011_delayed_dark_adaptation1.11666883
75MP0005410_abnormal_fertilization1.11394933
76MP0002069_abnormal_eating/drinking_beha1.10597998
77MP0006292_abnormal_olfactory_placode1.09535349
78MP0003119_abnormal_digestive_system1.08503066
79MP0005248_abnormal_Harderian_gland1.08331565
80MP0003861_abnormal_nervous_system1.07849535
81MP0003890_abnormal_embryonic-extraembry1.06439997
82MP0005083_abnormal_biliary_tract1.06211197
83MP0010030_abnormal_orbit_morphology1.03916025
84MP0001348_abnormal_lacrimal_gland1.01945480
85MP0000569_abnormal_digit_pigmentation1.01158780
86MP0001501_abnormal_sleep_pattern1.00458537
87MP0005551_abnormal_eye_electrophysiolog0.98842241
88MP0004885_abnormal_endolymph0.98189071
89MP0005187_abnormal_penis_morphology0.97071389
90MP0001944_abnormal_pancreas_morphology0.90401232
91MP0009764_decreased_sensitivity_to0.89887257
92MP0003646_muscle_fatigue0.88792165
93MP0002653_abnormal_ependyma_morphology0.88692648
94MP0002419_abnormal_innate_immunity0.88614794
95MP0003137_abnormal_impulse_conducting0.86813277
96MP0000538_abnormal_urinary_bladder0.86663199
97MP0004133_heterotaxia0.86214064
98MP0002752_abnormal_somatic_nervous0.85833896
99MP0004742_abnormal_vestibular_system0.85458526
100MP0005253_abnormal_eye_physiology0.84546339
101MP0005025_abnormal_response_to0.83670553
102MP0001800_abnormal_humoral_immune0.83573815
103MP0006072_abnormal_retinal_apoptosis0.83204820
104MP0002177_abnormal_outer_ear0.82642442
105MP0000534_abnormal_ureter_morphology0.81902475
106MP0001299_abnormal_eye_distance/0.80902560
107MP0003698_abnormal_male_reproductive0.80533182
108MP0000750_abnormal_muscle_regeneration0.79618022
109MP0005671_abnormal_response_to0.79580896
110MP0001485_abnormal_pinna_reflex0.79394745
111MP0005387_immune_system_phenotype0.78579734
112MP0001790_abnormal_immune_system0.78579734
113MP0002102_abnormal_ear_morphology0.76003769
114MP0002332_abnormal_exercise_endurance0.75317002
115MP0004085_abnormal_heartbeat0.75266385
116MP0002723_abnormal_immune_serum0.75084153
117MP0009785_altered_susceptibility_to0.74397900
118MP0003866_abnormal_defecation0.72231856
119MP0002420_abnormal_adaptive_immunity0.71410580
120MP0003879_abnormal_hair_cell0.71172966
121MP0001177_atelectasis0.70562520
122MP0001943_abnormal_respiration0.70546470
123MP0004142_abnormal_muscle_tone0.70381287
124MP0000751_myopathy0.70311525
125MP0001819_abnormal_immune_cell0.70294969
126MP0002938_white_spotting0.68595635
127MP0001963_abnormal_hearing_physiology0.67856390
128MP0002837_dystrophic_cardiac_calcinosis0.67650918
129MP0002081_perinatal_lethality0.67371808
130MP0005535_abnormal_body_temperature0.66747337
131MP0001664_abnormal_digestion0.66633054
132MP0003183_abnormal_peptide_metabolism0.66394968
133MP0003959_abnormal_lean_body0.66110658
134MP0003633_abnormal_nervous_system0.65701328
135MP0006035_abnormal_mitochondrial_morpho0.64758878
136MP0000015_abnormal_ear_pigmentation0.64545724
137MP0002229_neurodegeneration0.63687864
138MP0005409_darkened_coat_color0.62747824
139MP0002693_abnormal_pancreas_physiology0.61165032

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.24444523
2Focal motor seizures (HP:0011153)5.03836353
3Hypochromic microcytic anemia (HP:0004840)4.25470558
4Focal seizures (HP:0007359)4.17363148
5Limb dystonia (HP:0002451)3.68499780
6Supranuclear gaze palsy (HP:0000605)3.44675207
7Failure to thrive in infancy (HP:0001531)3.24907422
8Retrobulbar optic neuritis (HP:0100654)3.18464413
9Optic neuritis (HP:0100653)3.18464413
10Stomatitis (HP:0010280)3.18006942
11Ankle clonus (HP:0011448)3.06588637
12Amblyopia (HP:0000646)2.99567914
13Orchitis (HP:0100796)2.98914207
14Febrile seizures (HP:0002373)2.98449509
15Myositis (HP:0100614)2.91415404
16Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.88865654
17Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.86304462
18Degeneration of the lateral corticospinal tracts (HP:0002314)2.86304462
19Nephrogenic diabetes insipidus (HP:0009806)2.83447024
20Broad-based gait (HP:0002136)2.77884056
21Progressive cerebellar ataxia (HP:0002073)2.77066273
22Epileptic encephalopathy (HP:0200134)2.75108386
23Eczematoid dermatitis (HP:0000976)2.72522340
24Urinary urgency (HP:0000012)2.70001875
25Agitation (HP:0000713)2.68847406
26Congenital primary aphakia (HP:0007707)2.67231426
27Polyphagia (HP:0002591)2.67148909
28Torticollis (HP:0000473)2.67102082
29Recurrent bacterial skin infections (HP:0005406)2.63440855
30Anxiety (HP:0000739)2.59541672
31Focal dystonia (HP:0004373)2.58842646
32Visual hallucinations (HP:0002367)2.54827699
33Pancreatic cysts (HP:0001737)2.54241380
34Drooling (HP:0002307)2.53724946
35Excessive salivation (HP:0003781)2.53724946
36Atonic seizures (HP:0010819)2.53436552
37Retinal dysplasia (HP:0007973)2.53194219
38Hypochromic anemia (HP:0001931)2.52347431
39Depression (HP:0000716)2.52147614
40Spastic tetraplegia (HP:0002510)2.51041264
41Pachygyria (HP:0001302)2.49969693
42Abnormal eating behavior (HP:0100738)2.49839567
43Pheochromocytoma (HP:0002666)2.49765479
44Recurrent abscess formation (HP:0002722)2.46753814
45True hermaphroditism (HP:0010459)2.46522076
46Spastic gait (HP:0002064)2.44781126
47Pancreatic fibrosis (HP:0100732)2.42337909
48Protruding tongue (HP:0010808)2.40341188
49Craniofacial dystonia (HP:0012179)2.37656011
50Abnormality of midbrain morphology (HP:0002418)2.37503453
51Molar tooth sign on MRI (HP:0002419)2.37503453
52Impaired vibration sensation in the lower limbs (HP:0002166)2.34645745
53Hypsarrhythmia (HP:0002521)2.32640054
54Labial hypoplasia (HP:0000066)2.30574998
55EEG with generalized epileptiform discharges (HP:0011198)2.30379165
56Truncal ataxia (HP:0002078)2.30333661
57Poor eye contact (HP:0000817)2.30107316
58Neuroendocrine neoplasm (HP:0100634)2.29906536
59Lissencephaly (HP:0001339)2.29274987
60Abnormality of the heme biosynthetic pathway (HP:0010472)2.28873788
61Anomalous pulmonary venous return (HP:0010772)2.28587551
62Chronic hepatic failure (HP:0100626)2.27952932
63Progressive sensorineural hearing impairment (HP:0000408)2.26591020
64Hypoplasia of the brainstem (HP:0002365)2.26171501
65Aplasia/Hypoplasia of the brainstem (HP:0007362)2.26171501
66Epileptiform EEG discharges (HP:0011182)2.26152304
67Progressive inability to walk (HP:0002505)2.24661296
68Stereotypic behavior (HP:0000733)2.23061047
69Pointed chin (HP:0000307)2.22727706
70Ventricular fibrillation (HP:0001663)2.21605276
71Specific learning disability (HP:0001328)2.21304470
72Bony spicule pigmentary retinopathy (HP:0007737)2.20677661
73Cortical dysplasia (HP:0002539)2.20074788
74Shoulder girdle muscle weakness (HP:0003547)2.19593921
75Esotropia (HP:0000565)2.17022146
76Dialeptic seizures (HP:0011146)2.16452297
77Morphological abnormality of the middle ear (HP:0008609)2.16231373
78Pendular nystagmus (HP:0012043)2.15992964
79Lower limb muscle weakness (HP:0007340)2.15834817
80Absence seizures (HP:0002121)2.15809190
81Keratoconjunctivitis (HP:0001096)2.15669355
82Exotropia (HP:0000577)2.15506170
83Insomnia (HP:0100785)2.14374712
84Cutaneous finger syndactyly (HP:0010554)2.12285639
85Absent speech (HP:0001344)2.11784240
86Vaginal atresia (HP:0000148)2.10791849
87Hypoventilation (HP:0002791)2.08940960
88Keratoconjunctivitis sicca (HP:0001097)2.08646901
89Gait imbalance (HP:0002141)2.08616468
90Genital tract atresia (HP:0001827)2.07764609
91Abnormal respiratory motile cilium morphology (HP:0005938)2.07393582
92Abnormal respiratory epithelium morphology (HP:0012253)2.07393582
93Ankyloglossia (HP:0010296)2.07135619
94Amyotrophic lateral sclerosis (HP:0007354)2.06468077
95Peripheral hypomyelination (HP:0007182)2.06447520
96Annular pancreas (HP:0001734)2.05053789
97Abnormality of the labia minora (HP:0012880)2.04878054
98Hyperventilation (HP:0002883)2.03605367
99Abnormal pancreas size (HP:0012094)2.02821271
100Nephronophthisis (HP:0000090)2.01838709
101Abnormality of calcium-phosphate metabolism (HP:0100530)2.01676434
102Abnormality of the lower motor neuron (HP:0002366)2.01623825
103Recurrent gram-negative bacterial infections (HP:0005420)1.99957622
104Severe visual impairment (HP:0001141)1.98945258
105Abnormal hair whorl (HP:0010721)1.98700830
106Neoplasm of the heart (HP:0100544)1.97506139
107Truncus arteriosus (HP:0001660)1.97083433
108Hypoplastic female external genitalia (HP:0012815)1.96955870
109Scanning speech (HP:0002168)1.96675342
110Generalized hypotonia (HP:0001290)1.96097845
111Action tremor (HP:0002345)1.95636829
112Encephalitis (HP:0002383)1.95157732
113Abnormality of the corticospinal tract (HP:0002492)1.95030147
114Bicornuate uterus (HP:0000813)1.94953206
115Termporal pattern (HP:0011008)1.94920953
116Insidious onset (HP:0003587)1.94920953
117Morphological abnormality of the pyramidal tract (HP:0002062)1.94281500
118Atrophy/Degeneration involving motor neurons (HP:0007373)1.93768286
119Absent rod-and cone-mediated responses on ERG (HP:0007688)1.93539147
120Generalized tonic-clonic seizures (HP:0002069)1.92719092
121Papilledema (HP:0001085)1.92357157
122Atelectasis (HP:0100750)1.91053589
123Narrow forehead (HP:0000341)1.89670320
124Hypoplasia of the corpus callosum (HP:0002079)1.88628183
125Poor coordination (HP:0002370)1.88059459
126Growth hormone deficiency (HP:0000824)1.87515604
127Blue irides (HP:0000635)1.87206113
128Prolonged QT interval (HP:0001657)1.87184586
129Sleep apnea (HP:0010535)1.86924280
130Lower limb asymmetry (HP:0100559)1.85763032
131Episodic fever (HP:0001954)1.85721990
132Dysmetria (HP:0001310)1.85239913
133Optic nerve coloboma (HP:0000588)1.85090806
134Abnormal social behavior (HP:0012433)1.84380626
135Impaired social interactions (HP:0000735)1.84380626
136Bifid tongue (HP:0010297)1.84356345
137Absent eyebrow (HP:0002223)1.83851514
138Obsessive-compulsive behavior (HP:0000722)1.83631288
139Abnormality of the pulmonary veins (HP:0011718)1.83083176
140Cutaneous syndactyly (HP:0012725)1.82445974
141Abnormality of macrophages (HP:0004311)1.81873253
142Bronchomalacia (HP:0002780)1.81125945
143Ulnar claw (HP:0001178)1.81008710
144Anencephaly (HP:0002323)1.80790165
145Poor suck (HP:0002033)1.80398664
146Pelvic girdle muscle weakness (HP:0003749)1.79968041
147Gastrointestinal infarctions (HP:0005244)1.79739657
148Abnormal rod and cone electroretinograms (HP:0008323)1.79147391
149Mediastinal lymphadenopathy (HP:0100721)1.78529247
150Impaired smooth pursuit (HP:0007772)1.78187009
151Polymicrogyria (HP:0002126)1.77995650
152Urinary bladder sphincter dysfunction (HP:0002839)1.77947171
153Medial flaring of the eyebrow (HP:0010747)1.77661494
154Paraplegia (HP:0010550)1.77265501
155Narrow nasal bridge (HP:0000446)1.76157988
1563-Methylglutaconic aciduria (HP:0003535)1.75381339
157Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.75319787
158Abnormal EKG (HP:0003115)1.74935852
159Intellectual disability, severe (HP:0010864)1.74855805
160Dysdiadochokinesis (HP:0002075)1.74409603
161Restlessness (HP:0000711)1.74344753
162Obstructive lung disease (HP:0006536)1.73939208
163Autism (HP:0000717)1.72899922

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.90742439
2SIK33.71387922
3EPHA43.37712448
4MAP3K93.16569483
5ERBB33.11536869
6NTRK33.05316880
7MINK12.93452837
8WNK32.87817722
9KSR12.75706129
10MAP3K112.46621193
11TRIM282.41320820
12UHMK12.40755695
13EPHB12.32994144
14SIK22.23842967
15BCR2.17028278
16NTRK22.15996660
17DYRK22.12457464
18MAP4K22.07970873
19MAPK132.07470959
20EPHA31.75232307
21MAP3K41.65283836
22IRAK41.65068662
23PAK61.58613853
24KSR21.57248181
25DAPK21.57194759
26BMPR21.55038502
27CDK51.51354946
28TNK21.44329969
29MAP4K11.43920385
30TESK21.42141100
31CAMKK11.41566899
32MAP2K71.37756479
33PRKD31.36619340
34BLK1.34755181
35CAMKK21.33933470
36LIMK11.31031817
37TXK1.29065822
38SGK2231.28981539
39SGK4941.28981539
40GRK61.27503331
41MAP3K61.26968197
42CSNK1A1L1.26302567
43TAOK11.24731335
44CDK191.23538454
45PRPF4B1.16658561
46MAP3K21.15871660
47TYRO31.13961681
48CDK181.11379519
49AKT31.09575472
50PRKD21.07134042
51EPHB21.03871598
52MAP3K51.03796273
53PAK31.01345577
54STK381.00108399
55CDK140.98059207
56MARK30.97120380
57DYRK1A0.96901748
58CASK0.96832090
59BRAF0.94563865
60CSK0.94090594
61CDK150.94071943
62RPS6KA20.90539575
63MAPK150.90230037
64ARAF0.89904112
65BMPR1B0.88160655
66SGK20.88146240
67CSNK1G10.86944569
68CDK11A0.84753844
69RPS6KA40.83202235
70PDGFRA0.83076387
71MAP2K40.81047419
72DAPK10.80310042
73HCK0.77558963
74HIPK20.76964682
75CAMK2B0.76090672
76TAOK30.76051286
77PRKCG0.76021305
78MAP3K120.74535415
79TESK10.73961470
80INSRR0.73317534
81STK110.72697939
82PRKCZ0.72591925
83BRD40.70666273
84ADRBK20.70661396
85MARK20.70525520
86BTK0.69003570
87MAP2K30.68359519
88JAK20.67601196
89MATK0.67056941
90TNIK0.66521472
91CAMK2A0.63974068
92SYK0.62000813
93LATS20.61602184
94FGFR20.60845823
95BRSK10.60643625
96NTRK10.60490048
97FGR0.60469936
98SCYL20.57026755
99PHKG20.56610085
100PHKG10.56610085
101OXSR10.56442635
102PNCK0.55808144
103FER0.55725106
104LYN0.54506621
105GRK70.54412384
106CSNK1G20.54378927
107MAP3K10.53750118
108IRAK10.53521591
109FES0.53324805
110DYRK1B0.52980635
111PKN10.52890087
112PINK10.51797877
113MAP2K10.50925291
114RET0.50657718
115PASK0.50003747
116SRPK10.45716659
117LCK0.45387430
118DYRK30.45276030
119MAPK90.44073646
120IKBKE0.43532440
121ROCK10.43340801
122PRKCE0.42814885
123SGK10.42154375
124RIPK40.41363950
125CAMK40.41243000
126PRKAA10.41227319
127BCKDK0.41127057
128CCNB10.41067955
129SGK30.41047529
130ADRBK10.40919031
131CDC42BPA0.40476467
132GRK50.38354879
133LMTK20.37918821
134MAPK80.36373617
135CSNK1G30.35454926
136CAMK1G0.35283664
137CAMK10.35245433
138PRKCQ0.35214072
139FRK0.34380409
140TYK20.34133731
141PRKCH0.33154375
142YES10.32887068
143FYN0.32274428
144VRK10.32015205
145ERBB20.31490750
146RPS6KB10.30729295
147RPS6KA30.30493793
148MAPK100.29993994

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.12541664
2Olfactory transduction_Homo sapiens_hsa047402.94823062
3Synaptic vesicle cycle_Homo sapiens_hsa047212.80964218
4Cocaine addiction_Homo sapiens_hsa050302.80086125
5Dopaminergic synapse_Homo sapiens_hsa047282.58903325
6GABAergic synapse_Homo sapiens_hsa047272.58441328
7Circadian entrainment_Homo sapiens_hsa047132.55415723
8Amphetamine addiction_Homo sapiens_hsa050312.47742776
9Morphine addiction_Homo sapiens_hsa050322.45924434
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.38985054
11Long-term potentiation_Homo sapiens_hsa047202.34136249
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.29872679
13Glutamatergic synapse_Homo sapiens_hsa047242.26322549
14Insulin secretion_Homo sapiens_hsa049112.20302709
15Cholinergic synapse_Homo sapiens_hsa047252.16860851
16Serotonergic synapse_Homo sapiens_hsa047261.96549411
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.95681227
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.87350494
19Axon guidance_Homo sapiens_hsa043601.86671197
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.83809214
21Taste transduction_Homo sapiens_hsa047421.78013226
22Phagosome_Homo sapiens_hsa041451.68548540
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.67513336
24Gap junction_Homo sapiens_hsa045401.62068318
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.54917043
26Osteoclast differentiation_Homo sapiens_hsa043801.50586224
27Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.44323377
28Oxytocin signaling pathway_Homo sapiens_hsa049211.42972132
29Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.42176969
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39121127
31Long-term depression_Homo sapiens_hsa047301.39096564
32Renin secretion_Homo sapiens_hsa049241.36571481
33Alcoholism_Homo sapiens_hsa050341.35659316
34Chemokine signaling pathway_Homo sapiens_hsa040621.32894170
35Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.31598000
36Tuberculosis_Homo sapiens_hsa051521.29217192
37GnRH signaling pathway_Homo sapiens_hsa049121.28294300
38Gastric acid secretion_Homo sapiens_hsa049711.27656359
39Salivary secretion_Homo sapiens_hsa049701.24757006
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23354950
41ErbB signaling pathway_Homo sapiens_hsa040121.21426358
42Phototransduction_Homo sapiens_hsa047441.19998878
43Oxidative phosphorylation_Homo sapiens_hsa001901.18124548
44Melanogenesis_Homo sapiens_hsa049161.16812523
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15188197
46Type II diabetes mellitus_Homo sapiens_hsa049301.14174202
47Vibrio cholerae infection_Homo sapiens_hsa051101.12633776
48Oocyte meiosis_Homo sapiens_hsa041141.09842987
49NOD-like receptor signaling pathway_Homo sapiens_hsa046211.07539089
50Glioma_Homo sapiens_hsa052141.05975128
51Salmonella infection_Homo sapiens_hsa051321.03171967
52Estrogen signaling pathway_Homo sapiens_hsa049151.02870993
53cAMP signaling pathway_Homo sapiens_hsa040241.01962661
54Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.01728265
55Endometrial cancer_Homo sapiens_hsa052131.00666648
56Neurotrophin signaling pathway_Homo sapiens_hsa047220.99251034
57Calcium signaling pathway_Homo sapiens_hsa040200.98608887
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97411457
59Leishmaniasis_Homo sapiens_hsa051400.94760645
60Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93197661
61Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.91559559
62Collecting duct acid secretion_Homo sapiens_hsa049660.88254142
63Toll-like receptor signaling pathway_Homo sapiens_hsa046200.88220941
64Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.85698157
65Legionellosis_Homo sapiens_hsa051340.84538881
66Cardiac muscle contraction_Homo sapiens_hsa042600.83870181
67Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83073780
68Wnt signaling pathway_Homo sapiens_hsa043100.82027466
69Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.81807210
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80829065
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80781164
72Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80753819
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.79473584
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77960194
75Ether lipid metabolism_Homo sapiens_hsa005650.77474415
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.75647107
77Circadian rhythm_Homo sapiens_hsa047100.74433730
78RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74121629
79Prion diseases_Homo sapiens_hsa050200.73837126
80Type I diabetes mellitus_Homo sapiens_hsa049400.72144120
81Non-small cell lung cancer_Homo sapiens_hsa052230.71366075
82MAPK signaling pathway_Homo sapiens_hsa040100.70972142
83T cell receptor signaling pathway_Homo sapiens_hsa046600.70405464
84Colorectal cancer_Homo sapiens_hsa052100.70072210
85Thyroid hormone synthesis_Homo sapiens_hsa049180.68555404
86VEGF signaling pathway_Homo sapiens_hsa043700.67914573
87cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67587606
88Renal cell carcinoma_Homo sapiens_hsa052110.67366178
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67265894
90Staphylococcus aureus infection_Homo sapiens_hsa051500.66897373
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66758865
92Hedgehog signaling pathway_Homo sapiens_hsa043400.66501885
93Parkinsons disease_Homo sapiens_hsa050120.65271678
94Rap1 signaling pathway_Homo sapiens_hsa040150.64445107
95Malaria_Homo sapiens_hsa051440.63525618
96Ras signaling pathway_Homo sapiens_hsa040140.62964161
97Glycerophospholipid metabolism_Homo sapiens_hsa005640.62055282
98Jak-STAT signaling pathway_Homo sapiens_hsa046300.61727478
99Glucagon signaling pathway_Homo sapiens_hsa049220.59943200
100Viral myocarditis_Homo sapiens_hsa054160.58789220
101Hippo signaling pathway_Homo sapiens_hsa043900.58680753
102Acute myeloid leukemia_Homo sapiens_hsa052210.57267171
103Vascular smooth muscle contraction_Homo sapiens_hsa042700.57054571
104Notch signaling pathway_Homo sapiens_hsa043300.55580060
105Inositol phosphate metabolism_Homo sapiens_hsa005620.55505573
106B cell receptor signaling pathway_Homo sapiens_hsa046620.55431491
107Choline metabolism in cancer_Homo sapiens_hsa052310.54711122
108N-Glycan biosynthesis_Homo sapiens_hsa005100.54601030
109Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.54285205
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.53976160
111Alzheimers disease_Homo sapiens_hsa050100.53872773
112Insulin signaling pathway_Homo sapiens_hsa049100.53792764
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.53575458
114mTOR signaling pathway_Homo sapiens_hsa041500.51909933
115SNARE interactions in vesicular transport_Homo sapiens_hsa041300.51024140
116African trypanosomiasis_Homo sapiens_hsa051430.50992151
117Shigellosis_Homo sapiens_hsa051310.50839799
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.50776315
119Endocytosis_Homo sapiens_hsa041440.50709668
120Measles_Homo sapiens_hsa051620.50597269
121Dorso-ventral axis formation_Homo sapiens_hsa043200.50563374
122Thyroid cancer_Homo sapiens_hsa052160.50236214
123FoxO signaling pathway_Homo sapiens_hsa040680.50221817
124Linoleic acid metabolism_Homo sapiens_hsa005910.49053954
125Huntingtons disease_Homo sapiens_hsa050160.48996986
126Regulation of autophagy_Homo sapiens_hsa041400.48726800
127Primary immunodeficiency_Homo sapiens_hsa053400.48360221
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47980304
129Pancreatic secretion_Homo sapiens_hsa049720.47680575
130Graft-versus-host disease_Homo sapiens_hsa053320.47514381
131Hepatitis B_Homo sapiens_hsa051610.46892879
132Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46845929
133Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46643739
134Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45692446
135Prolactin signaling pathway_Homo sapiens_hsa049170.44297757
136Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43688574
137Dilated cardiomyopathy_Homo sapiens_hsa054140.43586589
138Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43448250
139Basal cell carcinoma_Homo sapiens_hsa052170.41712727
140Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.40571687
141Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40249977
142Tight junction_Homo sapiens_hsa045300.37415913
143Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.36593547
144Sphingolipid signaling pathway_Homo sapiens_hsa040710.36506409
145Butanoate metabolism_Homo sapiens_hsa006500.36388101

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