REPS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.76152434
2locomotory exploration behavior (GO:0035641)5.75861650
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.34150450
4vocalization behavior (GO:0071625)5.33523439
5synaptic vesicle maturation (GO:0016188)5.31661128
6synaptic vesicle exocytosis (GO:0016079)5.04860098
7glutamate secretion (GO:0014047)5.02682968
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.95146806
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.86356529
10regulation of glutamate receptor signaling pathway (GO:1900449)4.80480215
11regulation of synaptic vesicle exocytosis (GO:2000300)4.77470579
12synaptic vesicle docking involved in exocytosis (GO:0016081)4.66858116
13ionotropic glutamate receptor signaling pathway (GO:0035235)4.54279507
14regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.53035106
15exploration behavior (GO:0035640)4.42961854
16neurotransmitter secretion (GO:0007269)4.35087646
17protein localization to synapse (GO:0035418)4.31032795
18regulation of synaptic vesicle transport (GO:1902803)4.30759601
19neuronal action potential propagation (GO:0019227)4.27393839
20neurotransmitter-gated ion channel clustering (GO:0072578)4.22869255
21regulation of long-term neuronal synaptic plasticity (GO:0048169)4.22819604
22regulation of neuronal synaptic plasticity (GO:0048168)4.21754690
23neuron cell-cell adhesion (GO:0007158)4.18574994
24gamma-aminobutyric acid transport (GO:0015812)4.07618244
25synaptic transmission, glutamatergic (GO:0035249)4.03702928
26neuron-neuron synaptic transmission (GO:0007270)4.02834128
27glutamate receptor signaling pathway (GO:0007215)4.02293236
28regulation of synapse structural plasticity (GO:0051823)3.84841726
29long-term memory (GO:0007616)3.81322859
30L-amino acid import (GO:0043092)3.77252779
31regulation of excitatory postsynaptic membrane potential (GO:0060079)3.70693738
32membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.63213899
33cellular potassium ion homeostasis (GO:0030007)3.58463510
34positive regulation of membrane potential (GO:0045838)3.57748680
35proline transport (GO:0015824)3.57456898
36long-term synaptic potentiation (GO:0060291)3.54576830
37regulation of synaptic plasticity (GO:0048167)3.52306108
38neurotransmitter transport (GO:0006836)3.50834319
39regulation of postsynaptic membrane potential (GO:0060078)3.50306987
40gamma-aminobutyric acid signaling pathway (GO:0007214)3.43118604
41dendritic spine morphogenesis (GO:0060997)3.42234897
42layer formation in cerebral cortex (GO:0021819)3.40307255
43activation of protein kinase A activity (GO:0034199)3.40240123
44cerebellar granule cell differentiation (GO:0021707)3.39843538
45positive regulation of synapse maturation (GO:0090129)3.34063553
46regulation of synaptic transmission, glutamatergic (GO:0051966)3.32768572
47regulation of neurotransmitter levels (GO:0001505)3.31540712
48negative regulation of synaptic transmission, GABAergic (GO:0032229)3.30241401
49regulation of dendritic spine morphogenesis (GO:0061001)3.29989245
50positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.29551129
51response to histamine (GO:0034776)3.24232167
52regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.21022842
53serotonin metabolic process (GO:0042428)3.17658373
54synaptic vesicle endocytosis (GO:0048488)3.17425541
55regulation of neurotransmitter secretion (GO:0046928)3.16126791
56neuron recognition (GO:0008038)3.15168527
57neuronal ion channel clustering (GO:0045161)3.14809336
58transmission of nerve impulse (GO:0019226)3.13500176
59sodium ion export (GO:0071436)3.12560357
60negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.12364704
61neuromuscular process controlling balance (GO:0050885)3.10666867
62presynaptic membrane assembly (GO:0097105)3.10431763
63negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.09262001
64behavioral response to cocaine (GO:0048148)3.08619087
65regulation of female receptivity (GO:0045924)3.05631646
66positive regulation of synaptic transmission, GABAergic (GO:0032230)3.05512080
67cerebellar Purkinje cell differentiation (GO:0021702)3.03990373
68neuromuscular process controlling posture (GO:0050884)3.02899116
69positive regulation of neurotransmitter secretion (GO:0001956)3.02785847
70behavioral fear response (GO:0001662)3.02098379
71behavioral defense response (GO:0002209)3.02098379
72vesicle transport along microtubule (GO:0047496)2.98813057
73positive regulation of neurotransmitter transport (GO:0051590)2.98331406
74G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.96674457
75membrane depolarization (GO:0051899)2.96146142
76positive regulation of synaptic transmission (GO:0050806)2.94574387
77regulation of neurotransmitter transport (GO:0051588)2.94428019
78axon ensheathment in central nervous system (GO:0032291)2.92956344
79central nervous system myelination (GO:0022010)2.92956344
80regulation of vesicle fusion (GO:0031338)2.92734502
81cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.92469032
82regulation of ARF protein signal transduction (GO:0032012)2.92174653
83prepulse inhibition (GO:0060134)2.91962738
84long term synaptic depression (GO:0060292)2.91254323
85postsynaptic membrane organization (GO:0001941)2.90044760
86positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.89888537
87learning (GO:0007612)2.89696614
88auditory behavior (GO:0031223)2.89421606
89G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.89230021
90presynaptic membrane organization (GO:0097090)2.88636027
91innervation (GO:0060384)2.88293135
92axonal fasciculation (GO:0007413)2.86918947
93membrane depolarization during action potential (GO:0086010)2.86827646
94regulation of synaptic transmission (GO:0050804)2.86672693
95fear response (GO:0042596)2.85232604
96response to auditory stimulus (GO:0010996)2.84614788
97synaptic transmission (GO:0007268)2.84541683
98membrane hyperpolarization (GO:0060081)2.84517171
99amino acid import (GO:0043090)2.84313380
100female mating behavior (GO:0060180)2.83865811
101positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.83080799
102regulation of dendritic spine development (GO:0060998)2.82992719
103glycine transport (GO:0015816)2.82913944
104relaxation of smooth muscle (GO:0044557)2.82425758
105social behavior (GO:0035176)2.81898653
106intraspecies interaction between organisms (GO:0051703)2.81898653
107detection of molecule of bacterial origin (GO:0032490)2.80275540
108primary amino compound metabolic process (GO:1901160)2.78032204
109dendrite morphogenesis (GO:0048813)2.77083978
110negative regulation of dendrite morphogenesis (GO:0050774)2.76879220
111positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.76043064
112neuromuscular process (GO:0050905)2.75382937
113regulation of beta-amyloid formation (GO:1902003)2.75288195
114negative regulation of dendrite development (GO:2000171)2.75163060
115regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.72456381
116potassium ion import (GO:0010107)2.70976196
117cell differentiation in hindbrain (GO:0021533)2.63409188
118microglial cell activation (GO:0001774)2.63174786
119regulation of voltage-gated calcium channel activity (GO:1901385)2.60178909
120negative regulation of cytosolic calcium ion concentration (GO:0051481)2.56493919
121startle response (GO:0001964)2.48343950
122neurotransmitter uptake (GO:0001504)2.47187964
123regulation of exocytosis (GO:0017157)2.47176804
124relaxation of cardiac muscle (GO:0055119)2.44577525
125detection of calcium ion (GO:0005513)2.44227811
126cellular response to ethanol (GO:0071361)2.42889516
127regulation of clathrin-mediated endocytosis (GO:2000369)2.40888349
128macroautophagy (GO:0016236)2.40386018
129import into cell (GO:0098657)2.38411669
130cellular sodium ion homeostasis (GO:0006883)2.38352138
131cellular potassium ion transport (GO:0071804)2.36345276
132potassium ion transmembrane transport (GO:0071805)2.36345276
133cellular response to epinephrine stimulus (GO:0071872)2.35157281
134regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.34625613
135positive regulation of myoblast differentiation (GO:0045663)2.33604428
136positive regulation of Rap GTPase activity (GO:0032854)2.32545370
137adult walking behavior (GO:0007628)2.30471942
138establishment of protein localization to Golgi (GO:0072600)2.30170256
139regulation of calcium ion-dependent exocytosis (GO:0017158)2.29892703
140regulation of Rap GTPase activity (GO:0032317)2.29461934
141macrophage activation involved in immune response (GO:0002281)2.28760958
142positive regulation of cellular amide metabolic process (GO:0034250)2.28486986
143negative regulation of neurotransmitter transport (GO:0051589)2.26644531
144potassium ion transport (GO:0006813)2.24863958
145macrophage activation (GO:0042116)2.24305552
146regulation of amyloid precursor protein catabolic process (GO:1902991)2.23728077

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.52115274
2GBX2_23144817_ChIP-Seq_PC3_Human3.61614653
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98320843
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.92897599
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.77516370
6REST_21632747_ChIP-Seq_MESCs_Mouse2.60209166
7RARB_27405468_Chip-Seq_BRAIN_Mouse2.51056482
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.50404382
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.49961328
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.49961328
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.41338213
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.41307814
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.40641340
14DROSHA_22980978_ChIP-Seq_HELA_Human2.36741465
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.34702416
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.30470344
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.13727926
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.13469810
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.07961835
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.03466405
21EZH2_27294783_Chip-Seq_ESCs_Mouse1.99635037
22TAF15_26573619_Chip-Seq_HEK293_Human1.99397637
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.92722513
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.92280575
25RNF2_27304074_Chip-Seq_ESCs_Mouse1.92009708
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.86863798
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.81474072
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.80647202
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.77763525
30IKZF1_21737484_ChIP-ChIP_HCT116_Human1.75420369
31* SMAD4_21799915_ChIP-Seq_A2780_Human1.72631696
32AR_21572438_ChIP-Seq_LNCaP_Human1.70774017
33* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.69320744
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.68970120
35CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59344403
36CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.57345846
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.53157384
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.48245672
39EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47317573
40* P300_19829295_ChIP-Seq_ESCs_Human1.41958191
41SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.41200901
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40853386
43NR3C1_23031785_ChIP-Seq_PC12_Mouse1.37236026
44SOX2_21211035_ChIP-Seq_LN229_Gbm1.36495024
45* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34935239
46TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32553948
47AR_25329375_ChIP-Seq_VCAP_Human1.31797116
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.31422915
49STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.30321599
50* SMAD3_21741376_ChIP-Seq_EPCs_Human1.27726589
51ZNF274_21170338_ChIP-Seq_K562_Hela1.26237185
52STAT3_23295773_ChIP-Seq_U87_Human1.26213397
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.24739045
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24369682
55ESR1_20079471_ChIP-ChIP_T-47D_Human1.24335193
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23023654
57GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22760639
58TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21680911
59POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21680911
60AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20149212
61* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18930629
62SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18406171
63ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.18352994
64AR_19668381_ChIP-Seq_PC3_Human1.18245623
65PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.16655957
66SMAD_19615063_ChIP-ChIP_OVARY_Human1.16140342
67RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.15002994
68Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.14415033
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.14303887
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13977655
71CTNNB1_20460455_ChIP-Seq_HCT116_Human1.12730875
72FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.12456957
73RING1B_27294783_Chip-Seq_ESCs_Mouse1.11875050
74MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11777339
75TCF4_23295773_ChIP-Seq_U87_Human1.11327528
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11215748
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.10200170
78WT1_25993318_ChIP-Seq_PODOCYTE_Human1.10166535
79PCGF2_27294783_Chip-Seq_ESCs_Mouse1.09370984
80AHR_22903824_ChIP-Seq_MCF-7_Human1.08408743
81GATA2_21666600_ChIP-Seq_HMVEC_Human1.07396285
82P53_22127205_ChIP-Seq_FIBROBLAST_Human1.07066384
83PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.07053963
84FLI1_21867929_ChIP-Seq_TH2_Mouse1.06588377
85TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05668599
86GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05458024
87RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.05105768
88SCL_19346495_ChIP-Seq_HPC-7_Human1.04924681
89VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04333361
90TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04259581
91POU3F2_20337985_ChIP-ChIP_501MEL_Human1.03882407
92VDR_22108803_ChIP-Seq_LS180_Human1.03053018
93SUZ12_27294783_Chip-Seq_NPCs_Mouse1.02814560
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01799545
95PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01147291
96TP53_16413492_ChIP-PET_HCT116_Human1.00304851
97RUNX2_22187159_ChIP-Seq_PCA_Human0.99903915
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.99359005
99IRF8_22096565_ChIP-ChIP_GC-B_Human0.99265256
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98692392
101PRDM14_20953172_ChIP-Seq_ESCs_Human0.98349455
102CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.98346098
103BCAT_22108803_ChIP-Seq_LS180_Human0.97655425
104NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97461583
105NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97461583
106* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97403839
107EZH2_27294783_Chip-Seq_NPCs_Mouse0.97312111
108RXR_22108803_ChIP-Seq_LS180_Human0.97025636
109P53_22387025_ChIP-Seq_ESCs_Mouse0.96373134
110TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.96276626
111YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96066238
112IGF1R_20145208_ChIP-Seq_DFB_Human0.94951369
113CBX2_27304074_Chip-Seq_ESCs_Mouse0.94927735
114* SMAD4_21741376_ChIP-Seq_HESCs_Human0.93896093
115BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93350521
116BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91574549
117* SMAD3_21741376_ChIP-Seq_HESCs_Human0.90909928
118ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.88789640
119RING1B_27294783_Chip-Seq_NPCs_Mouse0.88778205
120TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.87184343
121* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.86996298
122JUN_21703547_ChIP-Seq_K562_Human0.86945885
123TP53_18474530_ChIP-ChIP_U2OS_Human0.86368599
124FUS_26573619_Chip-Seq_HEK293_Human0.86296145
125SMAD3_21741376_ChIP-Seq_ESCs_Human0.86119808
126NANOG_18555785_Chip-Seq_ESCs_Mouse0.86035724
127RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.85292683
128GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84367032
129ER_23166858_ChIP-Seq_MCF-7_Human0.82783026
130* SMAD4_21741376_ChIP-Seq_EPCs_Human0.82069802

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.52377428
2MP0003880_abnormal_central_pattern4.71746892
3MP0003635_abnormal_synaptic_transmissio4.13152638
4MP0004270_analgesia3.63787320
5MP0009745_abnormal_behavioral_response3.50319216
6MP0002822_catalepsy3.41589943
7MP0002063_abnormal_learning/memory/cond3.34091703
8MP0002064_seizures3.21153880
9MP0009046_muscle_twitch3.01740015
10MP0001968_abnormal_touch/_nociception3.01592545
11MP0002572_abnormal_emotion/affect_behav2.80323641
12MP0002272_abnormal_nervous_system2.58263997
13MP0002734_abnormal_mechanical_nocicepti2.48168606
14MP0001486_abnormal_startle_reflex2.48047178
15MP0001501_abnormal_sleep_pattern2.40319310
16MP0009780_abnormal_chondrocyte_physiolo2.37285382
17MP0005423_abnormal_somatic_nervous2.32662125
18MP0002736_abnormal_nociception_after2.31907745
19MP0003724_increased_susceptibility_to2.21472903
20MP0002735_abnormal_chemical_nociception2.19342389
21MP0001440_abnormal_grooming_behavior2.07567027
22MP0003329_amyloid_beta_deposits1.99075656
23MP0002733_abnormal_thermal_nociception1.90670671
24MP0002067_abnormal_sensory_capabilities1.89786693
25MP0001970_abnormal_pain_threshold1.84678811
26MP0002909_abnormal_adrenal_gland1.82879519
27MP0005646_abnormal_pituitary_gland1.79492024
28MP0003045_fibrosis1.77264387
29MP0008569_lethality_at_weaning1.71625132
30MP0005386_behavior/neurological_phenoty1.68756042
31MP0004924_abnormal_behavior1.68756042
32MP0003879_abnormal_hair_cell1.65990580
33MP0004858_abnormal_nervous_system1.62626066
34MP0002557_abnormal_social/conspecific_i1.62287557
35MP0004811_abnormal_neuron_physiology1.58205728
36MP0002184_abnormal_innervation1.51308393
37MP0001984_abnormal_olfaction1.48866241
38MP0003633_abnormal_nervous_system1.48429240
39MP0006276_abnormal_autonomic_nervous1.42205634
40MP0008877_abnormal_DNA_methylation1.40166755
41MP0000778_abnormal_nervous_system1.36688452
42MP0004885_abnormal_endolymph1.36231519
43MP0002066_abnormal_motor_capabilities/c1.34930904
44MP0000955_abnormal_spinal_cord1.30033607
45MP0001529_abnormal_vocalization1.22459149
46MP0003303_peritoneal_inflammation1.21913576
47MP0008872_abnormal_physiological_respon1.21893796
48MP0003631_nervous_system_phenotype1.21307895
49MP0002882_abnormal_neuron_morphology1.19576454
50MP0005085_abnormal_gallbladder_physiolo1.18365433
51MP0003787_abnormal_imprinting1.17887065
52MP0005360_urolithiasis1.17472416
53MP0000604_amyloidosis1.16123231
54MP0002139_abnormal_hepatobiliary_system1.14792072
55MP0008874_decreased_physiological_sensi1.14742650
56MP0005535_abnormal_body_temperature1.13658045
57MP0001986_abnormal_taste_sensitivity1.13287272
58MP0002837_dystrophic_cardiac_calcinosis1.11239476
59MP0001502_abnormal_circadian_rhythm1.09600054
60MP0001905_abnormal_dopamine_level1.08139727
61MP0004142_abnormal_muscle_tone1.07234445
62MP0003075_altered_response_to1.06401375
63MP0000015_abnormal_ear_pigmentation1.06325473
64MP0008875_abnormal_xenobiotic_pharmacok1.06235182
65MP0005645_abnormal_hypothalamus_physiol1.05933583
66MP0003690_abnormal_glial_cell1.05502656
67MP0002876_abnormal_thyroid_physiology1.03483390
68MP0010386_abnormal_urinary_bladder1.03273811
69MP0002638_abnormal_pupillary_reflex1.01122808
70MP0004043_abnormal_pH_regulation1.00692273
71MP0002069_abnormal_eating/drinking_beha1.00342883
72MP0001177_atelectasis1.00246436
73MP0005310_abnormal_salivary_gland0.99457673
74MP0000013_abnormal_adipose_tissue0.98899446
75MP0008004_abnormal_stomach_pH0.96894004
76MP0005174_abnormal_tail_pigmentation0.96021658
77MP0002229_neurodegeneration0.95010450
78MP0001485_abnormal_pinna_reflex0.94624172
79MP0005464_abnormal_platelet_physiology0.89805684
80MP0002152_abnormal_brain_morphology0.88992124
81MP0000569_abnormal_digit_pigmentation0.84981653
82MP0004510_myositis0.84806096
83MP0001188_hyperpigmentation0.83539411
84MP0005365_abnormal_bile_salt0.82062107
85MP0005551_abnormal_eye_electrophysiolog0.81942020
86MP0003632_abnormal_nervous_system0.80929683
87MP0002090_abnormal_vision0.80181936
88MP0004085_abnormal_heartbeat0.80022500
89MP0010329_abnormal_lipoprotein_level0.79581381
90MP0010234_abnormal_vibrissa_follicle0.79508974
91MP0005167_abnormal_blood-brain_barrier0.78039825
92MP0004147_increased_porphyrin_level0.77548200
93MP0008961_abnormal_basal_metabolism0.76734419
94MP0000920_abnormal_myelination0.75749303
95MP0003122_maternal_imprinting0.73442424
96MP0003866_abnormal_defecation0.73428046
97MP0000230_abnormal_systemic_arterial0.70860332
98MP0001963_abnormal_hearing_physiology0.69600807
99MP0001664_abnormal_digestion0.69587602
100MP0003634_abnormal_glial_cell0.68288177
101MP0000751_myopathy0.67723342
102MP0004742_abnormal_vestibular_system0.67548365
103MP0001765_abnormal_ion_homeostasis0.66910127
104MP0002168_other_aberrant_phenotype0.66751492
105MP0004381_abnormal_hair_follicle0.64848746
106MP0005166_decreased_susceptibility_to0.64499264
107MP0002332_abnormal_exercise_endurance0.64340450
108MP0002419_abnormal_innate_immunity0.63520323
109MP0004484_altered_response_of0.61808677
110MP0004130_abnormal_muscle_cell0.61205016
111MP0003172_abnormal_lysosome_physiology0.61100725
112MP0003195_calcinosis0.61022395
113MP0003638_abnormal_response/metabolism_0.60886559
114MP0003252_abnormal_bile_duct0.60512973
115MP0002693_abnormal_pancreas_physiology0.60412566
116MP0003191_abnormal_cellular_cholesterol0.59637632
117MP0003283_abnormal_digestive_organ0.59078718
118MP0004215_abnormal_myocardial_fiber0.57871528
119MP0004145_abnormal_muscle_electrophysio0.57286019
120MP0005448_abnormal_energy_balance0.54692283
121MP0003183_abnormal_peptide_metabolism0.52783420
122MP0005584_abnormal_enzyme/coenzyme_acti0.52733176
123MP0005332_abnormal_amino_acid0.51463142
124MP0002078_abnormal_glucose_homeostasis0.51141316
125MP0002118_abnormal_lipid_homeostasis0.50504124

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.33829388
2Myokymia (HP:0002411)6.79543055
3Focal seizures (HP:0007359)5.84921145
4Visual hallucinations (HP:0002367)4.98550428
5Epileptic encephalopathy (HP:0200134)4.93180834
6Atonic seizures (HP:0010819)4.79152994
7Febrile seizures (HP:0002373)4.57082409
8Absence seizures (HP:0002121)4.47087952
9Hyperventilation (HP:0002883)4.33879270
10Generalized tonic-clonic seizures (HP:0002069)4.13396608
11Dialeptic seizures (HP:0011146)4.07773056
12Progressive cerebellar ataxia (HP:0002073)4.03543753
13Action tremor (HP:0002345)3.85698751
14Poor eye contact (HP:0000817)3.53265102
15Broad-based gait (HP:0002136)3.48233371
16Impaired vibration sensation in the lower limbs (HP:0002166)3.43286923
17Abnormal social behavior (HP:0012433)3.40823511
18Impaired social interactions (HP:0000735)3.40823511
19Gaze-evoked nystagmus (HP:0000640)3.33693626
20Supranuclear gaze palsy (HP:0000605)3.30394918
21Dysdiadochokinesis (HP:0002075)3.24916134
22Depression (HP:0000716)3.14947049
23Retrobulbar optic neuritis (HP:0100654)3.12383792
24Optic neuritis (HP:0100653)3.12383792
25Dysmetria (HP:0001310)3.12353242
26Anxiety (HP:0000739)3.10464672
27Postural instability (HP:0002172)3.10287828
28Urinary bladder sphincter dysfunction (HP:0002839)3.02870522
29Orchitis (HP:0100796)2.97521162
30Status epilepticus (HP:0002133)2.97080235
31Ankle clonus (HP:0011448)2.94721552
32Truncal ataxia (HP:0002078)2.90983887
33Abnormal eating behavior (HP:0100738)2.88121729
34Cerebral inclusion bodies (HP:0100314)2.84324810
35Neurofibrillary tangles (HP:0002185)2.83150042
36Torticollis (HP:0000473)2.80580227
37Excessive salivation (HP:0003781)2.80176262
38Drooling (HP:0002307)2.80176262
39Amblyopia (HP:0000646)2.80037828
40Epileptiform EEG discharges (HP:0011182)2.78621989
41Papilledema (HP:0001085)2.77320338
42Scanning speech (HP:0002168)2.75452190
43Focal dystonia (HP:0004373)2.72797996
44Abnormality of the lower motor neuron (HP:0002366)2.72752100
45Intention tremor (HP:0002080)2.67567397
46Progressive inability to walk (HP:0002505)2.63085649
47EEG with generalized epileptiform discharges (HP:0011198)2.62237520
48Myositis (HP:0100614)2.61971730
49Impaired smooth pursuit (HP:0007772)2.59627591
50Bradykinesia (HP:0002067)2.58208763
51Dysmetric saccades (HP:0000641)2.54835299
52Mutism (HP:0002300)2.53754510
53Urinary urgency (HP:0000012)2.52967171
54Impaired vibratory sensation (HP:0002495)2.51322321
55Spastic gait (HP:0002064)2.50271111
56Hypsarrhythmia (HP:0002521)2.50080456
57Insidious onset (HP:0003587)2.45360687
58Termporal pattern (HP:0011008)2.45360687
59Craniofacial dystonia (HP:0012179)2.44407298
60Generalized myoclonic seizures (HP:0002123)2.38619627
61Obstructive sleep apnea (HP:0002870)2.37234541
62Blue irides (HP:0000635)2.34353980
63Genetic anticipation (HP:0003743)2.32996981
64Absent speech (HP:0001344)2.31916579
65Stereotypic behavior (HP:0000733)2.31382764
66Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.31193394
67Degeneration of the lateral corticospinal tracts (HP:0002314)2.31193394
68Pheochromocytoma (HP:0002666)2.28799062
69Abnormality of ocular smooth pursuit (HP:0000617)2.26409387
70Hemiplegia (HP:0002301)2.24856479
71Inability to walk (HP:0002540)2.24735900
72Abnormality of binocular vision (HP:0011514)2.24697687
73Diplopia (HP:0000651)2.24697687
74Hemiparesis (HP:0001269)2.21425120
75Resting tremor (HP:0002322)2.19563696
76Abnormality of the corticospinal tract (HP:0002492)2.18513003
77Stomatitis (HP:0010280)2.15644230
78Keratoconjunctivitis (HP:0001096)2.14933073
79Decreased circulating renin level (HP:0003351)2.12252986
80Syncope (HP:0001279)2.12146605
81Hypokalemic alkalosis (HP:0001949)2.08373414
82Prolonged QT interval (HP:0001657)2.05507670
83Keratoconjunctivitis sicca (HP:0001097)2.05311768
84Widely spaced teeth (HP:0000687)2.05075459
85Gait ataxia (HP:0002066)2.03664380
86Hyperaldosteronism (HP:0000859)2.02847303
87Agitation (HP:0000713)2.02555300
88Prolonged bleeding time (HP:0003010)2.00526138
89Psychosis (HP:0000709)2.00241919
90Neuronal loss in central nervous system (HP:0002529)1.99967161
91Lower limb muscle weakness (HP:0007340)1.99930992
92Ventricular fibrillation (HP:0001663)1.97962050
93Polyphagia (HP:0002591)1.97500368
94Neuroendocrine neoplasm (HP:0100634)1.96929083
95Clumsiness (HP:0002312)1.96226302
96Abnormal EKG (HP:0003115)1.94308710
97Fetal akinesia sequence (HP:0001989)1.93395441
98Generalized hypopigmentation of hair (HP:0011358)1.92542860
99Protruding tongue (HP:0010808)1.92073451
100Metabolic alkalosis (HP:0200114)1.92063429
101Rigidity (HP:0002063)1.91271480
102Megalencephaly (HP:0001355)1.91124739
103Vertigo (HP:0002321)1.91118265
104Pulmonary embolism (HP:0002204)1.90969286
105Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.90564942
106Gingival bleeding (HP:0000225)1.87478605
107Spontaneous hematomas (HP:0007420)1.87401011
108Hypochromic microcytic anemia (HP:0004840)1.87288712
109Annular pancreas (HP:0001734)1.86702321
110Abnormality of saccadic eye movements (HP:0000570)1.85445951
111Ocular albinism (HP:0001107)1.84770956
112Clonus (HP:0002169)1.84071754
113Abnormality of salivation (HP:0100755)1.83936330
114Incomplete penetrance (HP:0003829)1.83131631
115Delusions (HP:0000746)1.81613095
116Eczematoid dermatitis (HP:0000976)1.80271133
117Fair hair (HP:0002286)1.80129843
118Spastic tetraparesis (HP:0001285)1.79750796
119Limb dystonia (HP:0002451)1.78401713
120Memory impairment (HP:0002354)1.77845890
121Bundle branch block (HP:0011710)1.77006089
122Abnormality of renin-angiotensin system (HP:0000847)1.76322023
123Recurrent bacterial skin infections (HP:0005406)1.74649070
124Tetraplegia (HP:0002445)1.74483773
125Abnormality of the periventricular white matter (HP:0002518)1.71322238
126Postural tremor (HP:0002174)1.71199688
127Episodic fever (HP:0001954)1.70543466
128Global brain atrophy (HP:0002283)1.69817691
129Lower limb asymmetry (HP:0100559)1.69683146
130Papillary thyroid carcinoma (HP:0002895)1.67843907
131Testicular neoplasm (HP:0010788)1.66667237
132Amyotrophic lateral sclerosis (HP:0007354)1.66483348
133Iris hypopigmentation (HP:0007730)1.66373966
134Abnormal gallbladder physiology (HP:0012438)1.63713862
135Cholecystitis (HP:0001082)1.63713862
136Increased circulating renin level (HP:0000848)1.62341086
137Inappropriate behavior (HP:0000719)1.59594773

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.71058983
2NTRK34.52900450
3MAP3K93.59885993
4MAP3K43.19493307
5DAPK22.80719525
6MAP2K72.71230737
7MINK12.50591455
8RIPK42.40973189
9MAP2K42.35191782
10MARK12.34821066
11MAP3K122.20274912
12KSR22.17877178
13CASK2.07921921
14NTRK11.95290145
15PRKD31.94779235
16PAK61.92362742
17CAMKK11.91250624
18DAPK11.82105505
19NTRK21.75174148
20KSR11.52053926
21BLK1.50849490
22CDK51.49731088
23GRK51.43546551
24MAP3K21.41177784
25PLK21.39916050
26TAOK31.34970143
27STK381.33091759
28ARAF1.32978347
29ACVR1B1.32020501
30MAP3K131.30624702
31CDK191.29641115
32PRKCG1.27167503
33CAMKK21.26089733
34TNIK1.23341415
35FES1.21469162
36PRPF4B1.19182929
37PNCK1.14211049
38SGK2231.12305533
39SGK4941.12305533
40SIK21.11941504
41OXSR11.07989710
42SGK21.03591786
43CAMK2A1.03120211
44AKT31.02803494
45STK391.00854229
46BMPR20.95503747
47MAPK130.95178674
48IRAK10.94065575
49CAMK2B0.93241082
50IRAK20.92196299
51SGK30.91674318
52CAMK10.90776572
53PINK10.89117053
54PTK2B0.88988526
55RET0.87040688
56PRKCH0.86274887
57JAK20.86061599
58JAK10.85503176
59IRAK40.84484376
60UHMK10.83937863
61TYRO30.83736313
62MAPK120.81061710
63SYK0.80865270
64PDK10.80084943
65STK110.79383109
66RAF10.75826325
67PDPK10.75368127
68SGK10.74708665
69CDK180.73998626
70MAP3K10.72969476
71BMPR1B0.71543556
72CDK150.71450578
73CDK140.70179712
74LATS20.68454372
75INSRR0.68445562
76TXK0.66667661
77TAOK10.65828722
78FGFR30.64986450
79ADRBK20.64493269
80PAK30.64271421
81GRK60.60516831
82EPHA30.59823527
83HIPK20.59753908
84ERBB20.59434098
85CDK11A0.59199613
86MAP3K70.58804874
87PRKCE0.56281216
88CSNK1G20.56000500
89HCK0.55647597
90PRKCZ0.55627032
91PHKG10.54559384
92PHKG20.54559384
93FER0.54405419
94CAMK2G0.54173316
95TEC0.53769437
96FRK0.53421270
97TNK20.53320569
98DYRK1A0.52862732
99WNK30.52175913
100LMTK20.52013516
101YES10.51806644
102CAMK2D0.51181476
103PRKAA20.50455686
104RPS6KA30.49896825
105MAP2K10.49752920
106ADRBK10.49021392
107CCNB10.48907624
108MAP3K60.48069011
109NME10.47879411
110SCYL20.46404337
111MARK20.45929247
112MAP2K60.45226013
113FYN0.44779502
114CAMK1G0.44415777
115CAMK40.44130451
116ALK0.43798939
117PRKG10.43187519
118MAP4K20.41123531
119FGR0.39344812
120NEK60.39273444
121FGFR20.38057473
122WNK10.37926603
123MAPK100.37505638
124BRAF0.36005372
125DAPK30.35868039
126SIK30.35652020
127RIPK10.35058311
128PRKCB0.33814395

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.55623891
2Synaptic vesicle cycle_Homo sapiens_hsa047213.10315688
3GABAergic synapse_Homo sapiens_hsa047272.61170109
4Long-term potentiation_Homo sapiens_hsa047202.56592037
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.53944679
6Circadian entrainment_Homo sapiens_hsa047132.49532762
7Olfactory transduction_Homo sapiens_hsa047402.49264120
8Glutamatergic synapse_Homo sapiens_hsa047242.40789512
9Amphetamine addiction_Homo sapiens_hsa050312.34684282
10Morphine addiction_Homo sapiens_hsa050322.33557128
11Nitrogen metabolism_Homo sapiens_hsa009102.25587003
12Salivary secretion_Homo sapiens_hsa049702.10937492
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.08345548
14Dopaminergic synapse_Homo sapiens_hsa047281.96830524
15Insulin secretion_Homo sapiens_hsa049111.92167154
16Gastric acid secretion_Homo sapiens_hsa049711.74848329
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.71214170
18Cholinergic synapse_Homo sapiens_hsa047251.67405805
19Taste transduction_Homo sapiens_hsa047421.65454238
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.62618309
21Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.62605455
22Renin secretion_Homo sapiens_hsa049241.60089871
23Long-term depression_Homo sapiens_hsa047301.60052486
24Collecting duct acid secretion_Homo sapiens_hsa049661.59613331
25Calcium signaling pathway_Homo sapiens_hsa040201.44760024
26Serotonergic synapse_Homo sapiens_hsa047261.43920378
27Cocaine addiction_Homo sapiens_hsa050301.43728829
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.43151225
29Oxytocin signaling pathway_Homo sapiens_hsa049211.41253965
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39052845
31GnRH signaling pathway_Homo sapiens_hsa049121.23907064
32Arginine biosynthesis_Homo sapiens_hsa002201.22992987
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.20464531
34Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.20151215
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17846779
36Type II diabetes mellitus_Homo sapiens_hsa049301.16622780
37Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.12280700
38cAMP signaling pathway_Homo sapiens_hsa040241.11241555
39Gap junction_Homo sapiens_hsa045401.10918702
40ABC transporters_Homo sapiens_hsa020101.10266068
41Bile secretion_Homo sapiens_hsa049761.07554753
42Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05589257
43Histidine metabolism_Homo sapiens_hsa003401.03286699
44Platelet activation_Homo sapiens_hsa046111.00670503
45Glioma_Homo sapiens_hsa052140.96410245
46Estrogen signaling pathway_Homo sapiens_hsa049150.96404427
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.95300369
48Butanoate metabolism_Homo sapiens_hsa006500.94411568
49Primary bile acid biosynthesis_Homo sapiens_hsa001200.93104199
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.89351961
51Vibrio cholerae infection_Homo sapiens_hsa051100.88991123
52Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.88161406
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87461058
54Pancreatic secretion_Homo sapiens_hsa049720.85585615
55Osteoclast differentiation_Homo sapiens_hsa043800.83787060
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83006599
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.82144488
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81035628
59Thyroid hormone synthesis_Homo sapiens_hsa049180.80882137
60Melanogenesis_Homo sapiens_hsa049160.80503612
61ErbB signaling pathway_Homo sapiens_hsa040120.78729426
62Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.73895418
63Staphylococcus aureus infection_Homo sapiens_hsa051500.71852404
64Axon guidance_Homo sapiens_hsa043600.68240261
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.67840745
66Dorso-ventral axis formation_Homo sapiens_hsa043200.67744056
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66323769
68Chemokine signaling pathway_Homo sapiens_hsa040620.65922566
69Tuberculosis_Homo sapiens_hsa051520.65703354
70Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65115813
71Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.64325321
72Cardiac muscle contraction_Homo sapiens_hsa042600.61349885
73Glucagon signaling pathway_Homo sapiens_hsa049220.61077187
74B cell receptor signaling pathway_Homo sapiens_hsa046620.60745885
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.60503234
76Ether lipid metabolism_Homo sapiens_hsa005650.58576660
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57655939
78Regulation of autophagy_Homo sapiens_hsa041400.57486353
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.56187188
80Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.56082889
81Choline metabolism in cancer_Homo sapiens_hsa052310.55984287
82Linoleic acid metabolism_Homo sapiens_hsa005910.52558457
83beta-Alanine metabolism_Homo sapiens_hsa004100.52449685
84Oocyte meiosis_Homo sapiens_hsa041140.50653587
85Prion diseases_Homo sapiens_hsa050200.50520305
86Phototransduction_Homo sapiens_hsa047440.50126418
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.47580582
88FoxO signaling pathway_Homo sapiens_hsa040680.45367951
89Prolactin signaling pathway_Homo sapiens_hsa049170.45127618
90Leishmaniasis_Homo sapiens_hsa051400.45082357
91Type I diabetes mellitus_Homo sapiens_hsa049400.44666602
92MAPK signaling pathway_Homo sapiens_hsa040100.43998638
93Inositol phosphate metabolism_Homo sapiens_hsa005620.43660606
94Vitamin B6 metabolism_Homo sapiens_hsa007500.43609494
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.43589181
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.41122829
97African trypanosomiasis_Homo sapiens_hsa051430.40864056
98VEGF signaling pathway_Homo sapiens_hsa043700.40564543
99Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38185300
100Dilated cardiomyopathy_Homo sapiens_hsa054140.37990307
101Ras signaling pathway_Homo sapiens_hsa040140.37644319
102Rap1 signaling pathway_Homo sapiens_hsa040150.36256735
103mTOR signaling pathway_Homo sapiens_hsa041500.35789880
104Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.34454305
1052-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.34131242
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.33335646
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32727334
108Circadian rhythm_Homo sapiens_hsa047100.31733905
109Ovarian steroidogenesis_Homo sapiens_hsa049130.31573919
110Insulin signaling pathway_Homo sapiens_hsa049100.31219435
111Sphingolipid signaling pathway_Homo sapiens_hsa040710.30259190
112Glycerolipid metabolism_Homo sapiens_hsa005610.29632084
113Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29483013
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.28273952
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.27907071
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.27739860
117Non-small cell lung cancer_Homo sapiens_hsa052230.27612867
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.27252948
119Endocytosis_Homo sapiens_hsa041440.25918011
120Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.25841384
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.24506932
122Alzheimers disease_Homo sapiens_hsa050100.24315697
123Fatty acid biosynthesis_Homo sapiens_hsa000610.21935105
124Mineral absorption_Homo sapiens_hsa049780.21253247

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