

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protoporphyrinogen IX biosynthetic process (GO:0006782) | 9.97648390 |
| 2 | N-acetylneuraminate metabolic process (GO:0006054) | 9.21951404 |
| 3 | centriole replication (GO:0007099) | 7.99044081 |
| 4 | positive regulation of histone deacetylation (GO:0031065) | 7.75265150 |
| 5 | protoporphyrinogen IX metabolic process (GO:0046501) | 7.64826153 |
| 6 | cellular extravasation (GO:0045123) | 7.53884495 |
| 7 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 7.18147781 |
| 8 | regulation of MHC class II biosynthetic process (GO:0045346) | 6.62653134 |
| 9 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 6.54951518 |
| 10 | amino sugar catabolic process (GO:0046348) | 6.18688768 |
| 11 | positive regulation of protein deacetylation (GO:0090312) | 5.85776568 |
| 12 | N-acetylglucosamine metabolic process (GO:0006044) | 5.67208337 |
| 13 | reactive oxygen species biosynthetic process (GO:1903409) | 5.40355289 |
| 14 | purine deoxyribonucleotide catabolic process (GO:0009155) | 5.36070771 |
| 15 | positive regulation of chemokine biosynthetic process (GO:0045080) | 5.32747036 |
| 16 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 5.30733259 |
| 17 | centriole assembly (GO:0098534) | 5.24718636 |
| 18 | microglial cell activation (GO:0001774) | 5.14558918 |
| 19 | regulation of synapse structural plasticity (GO:0051823) | 5.08647516 |
| 20 | negative regulation of phagocytosis (GO:0050765) | 5.02726816 |
| 21 | thalamus development (GO:0021794) | 4.99169968 |
| 22 | base-excision repair, AP site formation (GO:0006285) | 4.94982268 |
| 23 | regulation of chemokine biosynthetic process (GO:0045073) | 4.81855358 |
| 24 | cellular response to cadmium ion (GO:0071276) | 4.66993005 |
| 25 | macrophage chemotaxis (GO:0048246) | 4.65913475 |
| 26 | cytokinetic process (GO:0032506) | 4.48188084 |
| 27 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 4.44986167 |
| 28 | regulation of growth of symbiont in host (GO:0044126) | 4.44986167 |
| 29 | negative regulation of growth of symbiont in host (GO:0044130) | 4.44986167 |
| 30 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 4.44986167 |
| 31 | negative regulation of interleukin-2 production (GO:0032703) | 4.37704710 |
| 32 | response to misfolded protein (GO:0051788) | 4.36987408 |
| 33 | response to folic acid (GO:0051593) | 4.36296506 |
| 34 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 4.28521200 |
| 35 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 4.28521200 |
| 36 | regulation of histone deacetylation (GO:0031063) | 4.15792383 |
| 37 | angiotensin maturation (GO:0002003) | 4.02119757 |
| 38 | behavioral response to nicotine (GO:0035095) | 3.98974810 |
| 39 | low-density lipoprotein particle remodeling (GO:0034374) | 3.96317034 |
| 40 | glial cell migration (GO:0008347) | 3.85578549 |
| 41 | regulation of fatty acid transport (GO:2000191) | 3.83511782 |
| 42 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.76201512 |
| 43 | prostate gland growth (GO:0060736) | 3.68483590 |
| 44 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.66703691 |
| 45 | cGMP-mediated signaling (GO:0019934) | 3.65838911 |
| 46 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.64361522 |
| 47 | signal complex assembly (GO:0007172) | 3.60869718 |
| 48 | induction of positive chemotaxis (GO:0050930) | 3.54246387 |
| 49 | heme biosynthetic process (GO:0006783) | 3.54195925 |
| 50 | regulation of protein import into nucleus, translocation (GO:0033158) | 3.40857390 |
| 51 | polyol transport (GO:0015791) | 3.40351885 |
| 52 | positive regulation of dendritic spine development (GO:0060999) | 3.39827000 |
| 53 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.30350098 |
| 54 | glomerular visceral epithelial cell development (GO:0072015) | 3.27196529 |
| 55 | neutrophil mediated immunity (GO:0002446) | 3.20934800 |
| 56 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.19227533 |
| 57 | regulation of glycolytic process (GO:0006110) | 3.17779332 |
| 58 | regulation of sequestering of triglyceride (GO:0010889) | 3.15133653 |
| 59 | glomerular filtration (GO:0003094) | 3.13281241 |
| 60 | glucosamine-containing compound metabolic process (GO:1901071) | 3.08053338 |
| 61 | response to oxygen radical (GO:0000305) | 3.06399692 |
| 62 | regulation of vascular permeability (GO:0043114) | 3.04715503 |
| 63 | relaxation of smooth muscle (GO:0044557) | 3.04419507 |
| 64 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.03450484 |
| 65 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.03450484 |
| 66 | removal of superoxide radicals (GO:0019430) | 3.00355530 |
| 67 | cellular response to superoxide (GO:0071451) | 3.00355530 |
| 68 | cellular response to oxygen radical (GO:0071450) | 3.00355530 |
| 69 | regulation of G0 to G1 transition (GO:0070316) | 2.99450514 |
| 70 | regulation of protein deacetylation (GO:0090311) | 2.94130859 |
| 71 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.91944820 |
| 72 | purine deoxyribonucleotide metabolic process (GO:0009151) | 2.86983041 |
| 73 | glomerular epithelial cell development (GO:0072310) | 2.84942032 |
| 74 | endothelium development (GO:0003158) | 2.83866887 |
| 75 | low-density lipoprotein particle clearance (GO:0034383) | 2.81896481 |
| 76 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.79782934 |
| 77 | gamma-aminobutyric acid transport (GO:0015812) | 2.77121103 |
| 78 | response to food (GO:0032094) | 2.75798427 |
| 79 | synaptic vesicle maturation (GO:0016188) | 2.72694275 |
| 80 | renal filtration (GO:0097205) | 2.66945276 |
| 81 | early endosome to late endosome transport (GO:0045022) | 2.64882743 |
| 82 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 2.64369217 |
| 83 | defense response to fungus (GO:0050832) | 2.63974425 |
| 84 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.62629886 |
| 85 | regulation of organic acid transport (GO:0032890) | 2.61629801 |
| 86 | sodium-independent organic anion transport (GO:0043252) | 2.60395092 |
| 87 | somatic diversification of immunoglobulins (GO:0016445) | 2.52550155 |
| 88 | regulation of neurotransmitter uptake (GO:0051580) | 2.49625696 |
| 89 | response to superoxide (GO:0000303) | 2.48944101 |
| 90 | glutamate receptor signaling pathway (GO:0007215) | 2.47367544 |
| 91 | lymphangiogenesis (GO:0001946) | 2.46301232 |
| 92 | phosphatidylglycerol biosynthetic process (GO:0006655) | 2.45521526 |
| 93 | regulation of carbohydrate catabolic process (GO:0043470) | 2.42877047 |
| 94 | regulation of cellular carbohydrate catabolic process (GO:0043471) | 2.42877047 |
| 95 | anatomical structure regression (GO:0060033) | 2.40802711 |
| 96 | potassium ion import (GO:0010107) | 2.37374468 |
| 97 | regulation of p38MAPK cascade (GO:1900744) | 2.36586610 |
| 98 | cardiolipin metabolic process (GO:0032048) | 2.34235903 |
| 99 | heme metabolic process (GO:0042168) | 2.34051025 |
| 100 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.30865114 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.93614077 |
| 2 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 3.56404662 |
| 3 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.11180878 |
| 4 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 3.11050784 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.53285828 |
| 6 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.30997571 |
| 7 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.26295454 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.19566444 |
| 9 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.11631540 |
| 10 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.90402979 |
| 11 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.90092203 |
| 12 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.79683552 |
| 13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.75466667 |
| 14 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.73142424 |
| 15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.65191967 |
| 16 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.64281729 |
| 17 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.64057458 |
| 18 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.58725768 |
| 19 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.54802437 |
| 20 | RXR_22108803_ChIP-Seq_LS180_Human | 1.54464052 |
| 21 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.53119827 |
| 22 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.52868156 |
| 23 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.51232716 |
| 24 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.48046925 |
| 25 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.47866400 |
| 26 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.47144392 |
| 27 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.44825710 |
| 28 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.42866025 |
| 29 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.42327028 |
| 30 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.42099661 |
| 31 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.38373835 |
| 32 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.37293190 |
| 33 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.35089498 |
| 34 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.34339778 |
| 35 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.33910254 |
| 36 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.28786516 |
| 37 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.28786516 |
| 38 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.25866318 |
| 39 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.24166258 |
| 40 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.22669337 |
| 41 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.20958388 |
| 42 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18836108 |
| 43 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.16993210 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11531428 |
| 45 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08369763 |
| 46 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.08307968 |
| 47 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.03934491 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.03340378 |
| 49 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.02536283 |
| 50 | TCF4_23295773_ChIP-Seq_U87_Human | 1.02394181 |
| 51 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02123399 |
| 52 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01731422 |
| 53 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.01380843 |
| 54 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.93622206 |
| 55 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.90804956 |
| 56 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.89899181 |
| 57 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.89893043 |
| 58 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.89810220 |
| 59 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.89172350 |
| 60 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.88156375 |
| 61 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.87744979 |
| 62 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.87744979 |
| 63 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.87442340 |
| 64 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.87012242 |
| 65 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.86690398 |
| 66 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.85054347 |
| 67 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.85029360 |
| 68 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.84771913 |
| 69 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.84334509 |
| 70 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.84185957 |
| 71 | AR_19668381_ChIP-Seq_PC3_Human | 0.83388406 |
| 72 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.82006938 |
| 73 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.81860410 |
| 74 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.81717188 |
| 75 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.80908347 |
| 76 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.80834547 |
| 77 | * CJUN_26792858_Chip-Seq_BT549_Human | 0.80766463 |
| 78 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.80640189 |
| 79 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.80526208 |
| 80 | STAT3_23295773_ChIP-Seq_U87_Human | 0.79631567 |
| 81 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.79234854 |
| 82 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.79206689 |
| 83 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.79136897 |
| 84 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79065308 |
| 85 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.78603011 |
| 86 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.78216943 |
| 87 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.77773430 |
| 88 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.75779852 |
| 89 | * NANOG_20526341_ChIP-Seq_ESCs_Human | 0.75338128 |
| 90 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.75032531 |
| 91 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.74937561 |
| 92 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.74836554 |
| 93 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.74587906 |
| 94 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.73567827 |
| 95 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.72717245 |
| 96 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.72528219 |
| 97 | TBL1_22424771_ChIP-Seq_293T_Human | 0.72362604 |
| 98 | AR_25329375_ChIP-Seq_VCAP_Human | 0.72300378 |
| 99 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.72237551 |
| 100 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.72199373 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005083_abnormal_biliary_tract | 8.55250495 |
| 2 | MP0005670_abnormal_white_adipose | 6.20026070 |
| 3 | MP0008961_abnormal_basal_metabolism | 4.43914757 |
| 4 | MP0005365_abnormal_bile_salt | 4.03773553 |
| 5 | MP0004043_abnormal_pH_regulation | 3.41599418 |
| 6 | MP0003252_abnormal_bile_duct | 3.05242533 |
| 7 | MP0005085_abnormal_gallbladder_physiolo | 2.78948126 |
| 8 | MP0000003_abnormal_adipose_tissue | 2.60066318 |
| 9 | MP0005375_adipose_tissue_phenotype | 2.44994967 |
| 10 | MP0010329_abnormal_lipoprotein_level | 2.29706595 |
| 11 | MP0009115_abnormal_fat_cell | 2.28699219 |
| 12 | MP0004885_abnormal_endolymph | 2.28085956 |
| 13 | MP0008058_abnormal_DNA_repair | 2.27194128 |
| 14 | MP0004130_abnormal_muscle_cell | 2.24066280 |
| 15 | MP0001502_abnormal_circadian_rhythm | 2.18399410 |
| 16 | MP0005666_abnormal_adipose_tissue | 2.07014264 |
| 17 | MP0005167_abnormal_blood-brain_barrier | 2.06454180 |
| 18 | MP0010368_abnormal_lymphatic_system | 2.06425699 |
| 19 | MP0002909_abnormal_adrenal_gland | 2.05612812 |
| 20 | MP0003690_abnormal_glial_cell | 2.04673389 |
| 21 | MP0001501_abnormal_sleep_pattern | 1.98804356 |
| 22 | MP0002971_abnormal_brown_adipose | 1.87659218 |
| 23 | MP0004742_abnormal_vestibular_system | 1.47344462 |
| 24 | MP0003880_abnormal_central_pattern | 1.46414465 |
| 25 | MP0003959_abnormal_lean_body | 1.45125749 |
| 26 | MP0005334_abnormal_fat_pad | 1.42530588 |
| 27 | MP0003879_abnormal_hair_cell | 1.38368896 |
| 28 | MP0005448_abnormal_energy_balance | 1.37603511 |
| 29 | MP0002970_abnormal_white_adipose | 1.35270226 |
| 30 | MP0010030_abnormal_orbit_morphology | 1.34511913 |
| 31 | MP0000230_abnormal_systemic_arterial | 1.30828569 |
| 32 | MP0000516_abnormal_urinary_system | 1.27560652 |
| 33 | MP0005367_renal/urinary_system_phenotyp | 1.27560652 |
| 34 | MP0004036_abnormal_muscle_relaxation | 1.26668715 |
| 35 | MP0000569_abnormal_digit_pigmentation | 1.24063601 |
| 36 | MP0001879_abnormal_lymphatic_vessel | 1.18206438 |
| 37 | MP0004859_abnormal_synaptic_plasticity | 1.17804692 |
| 38 | MP0002272_abnormal_nervous_system | 1.16894619 |
| 39 | MP0009745_abnormal_behavioral_response | 1.16022653 |
| 40 | MP0008872_abnormal_physiological_respon | 1.15723880 |
| 41 | MP0003329_amyloid_beta_deposits | 1.15251635 |
| 42 | MP0003123_paternal_imprinting | 1.13941741 |
| 43 | MP0002064_seizures | 1.13566572 |
| 44 | MP0003195_calcinosis | 1.09839298 |
| 45 | MP0005275_abnormal_skin_tensile | 1.08969335 |
| 46 | MP0003635_abnormal_synaptic_transmissio | 1.08873263 |
| 47 | MP0002118_abnormal_lipid_homeostasis | 1.08340761 |
| 48 | MP0008057_abnormal_DNA_replication | 1.08200986 |
| 49 | MP0004145_abnormal_muscle_electrophysio | 1.08160053 |
| 50 | MP0005551_abnormal_eye_electrophysiolog | 1.04671520 |
| 51 | MP0008875_abnormal_xenobiotic_pharmacok | 0.98135312 |
| 52 | MP0009643_abnormal_urine_homeostasis | 0.94251002 |
| 53 | MP0002572_abnormal_emotion/affect_behav | 0.94088132 |
| 54 | MP0005423_abnormal_somatic_nervous | 0.93008600 |
| 55 | MP0001486_abnormal_startle_reflex | 0.92813845 |
| 56 | MP0010386_abnormal_urinary_bladder | 0.90865806 |
| 57 | MP0005595_abnormal_vascular_smooth | 0.90174781 |
| 58 | MP0006138_congestive_heart_failure | 0.89874374 |
| 59 | MP0004019_abnormal_vitamin_homeostasis | 0.85797095 |
| 60 | MP0004270_analgesia | 0.84430262 |
| 61 | MP0002063_abnormal_learning/memory/cond | 0.83233500 |
| 62 | MP0005266_abnormal_metabolism | 0.82288515 |
| 63 | MP0000343_altered_response_to | 0.82164546 |
| 64 | MP0004084_abnormal_cardiac_muscle | 0.82036223 |
| 65 | MP0005452_abnormal_adipose_tissue | 0.79205518 |
| 66 | MP0004215_abnormal_myocardial_fiber | 0.78240116 |
| 67 | MP0005620_abnormal_muscle_contractility | 0.77282603 |
| 68 | MP0005503_abnormal_tendon_morphology | 0.77026200 |
| 69 | MP0009780_abnormal_chondrocyte_physiolo | 0.76400672 |
| 70 | MP0001984_abnormal_olfaction | 0.75255963 |
| 71 | MP0003633_abnormal_nervous_system | 0.73512138 |
| 72 | MP0004142_abnormal_muscle_tone | 0.72921102 |
| 73 | MP0008569_lethality_at_weaning | 0.72676904 |
| 74 | MP0000604_amyloidosis | 0.70981635 |
| 75 | MP0002127_abnormal_cardiovascular_syste | 0.70745492 |
| 76 | MP0003011_delayed_dark_adaptation | 0.69614678 |
| 77 | MP0002067_abnormal_sensory_capabilities | 0.69150740 |
| 78 | MP0000026_abnormal_inner_ear | 0.67206316 |
| 79 | MP0005174_abnormal_tail_pigmentation | 0.66910064 |
| 80 | MP0003828_pulmonary_edema | 0.66878667 |
| 81 | MP0004924_abnormal_behavior | 0.66722155 |
| 82 | MP0005386_behavior/neurological_phenoty | 0.66722155 |
| 83 | MP0002108_abnormal_muscle_morphology | 0.66526793 |
| 84 | MP0002069_abnormal_eating/drinking_beha | 0.66493339 |
| 85 | MP0005646_abnormal_pituitary_gland | 0.65118629 |
| 86 | MP0000538_abnormal_urinary_bladder | 0.63237606 |
| 87 | MP0003638_abnormal_response/metabolism_ | 0.62712791 |
| 88 | MP0001905_abnormal_dopamine_level | 0.62682450 |
| 89 | MP0002078_abnormal_glucose_homeostasis | 0.62531644 |
| 90 | MP0006276_abnormal_autonomic_nervous | 0.61713634 |
| 91 | MP0000249_abnormal_blood_vessel | 0.60711247 |
| 92 | MP0005164_abnormal_response_to | 0.60654881 |
| 93 | MP0008877_abnormal_DNA_methylation | 0.58727008 |
| 94 | MP0003632_abnormal_nervous_system | 0.57817268 |
| 95 | MP0003631_nervous_system_phenotype | 0.57799425 |
| 96 | MP0008874_decreased_physiological_sensi | 0.56416369 |
| 97 | MP0001963_abnormal_hearing_physiology | 0.56111253 |
| 98 | MP0003718_maternal_effect | 0.50832194 |
| 99 | MP0002734_abnormal_mechanical_nocicepti | 0.50669529 |
| 100 | MP0009046_muscle_twitch | 0.50455366 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Metabolic alkalosis (HP:0200114) | 4.55227832 |
| 2 | Diplopia (HP:0000651) | 4.04228863 |
| 3 | Abnormality of binocular vision (HP:0011514) | 4.04228863 |
| 4 | Tubulointerstitial fibrosis (HP:0005576) | 3.79839762 |
| 5 | Fair hair (HP:0002286) | 3.75975279 |
| 6 | Hypokalemic alkalosis (HP:0001949) | 3.72935805 |
| 7 | Generalized hyperpigmentation (HP:0007440) | 3.67502588 |
| 8 | Abnormality of chloride homeostasis (HP:0011422) | 3.55136076 |
| 9 | Abnormality of the prostate (HP:0008775) | 3.46596458 |
| 10 | Back pain (HP:0003418) | 3.34743074 |
| 11 | Anterior segment dysgenesis (HP:0007700) | 3.32017650 |
| 12 | Psychosis (HP:0000709) | 3.30911872 |
| 13 | Mesangial abnormality (HP:0001966) | 3.27355667 |
| 14 | Hyperaldosteronism (HP:0000859) | 3.21977645 |
| 15 | Neurofibrillary tangles (HP:0002185) | 3.21075864 |
| 16 | Protruding tongue (HP:0010808) | 3.18883503 |
| 17 | Epidermoid cyst (HP:0200040) | 3.18203420 |
| 18 | Clumsiness (HP:0002312) | 3.13594717 |
| 19 | Generalized hypopigmentation of hair (HP:0011358) | 3.09470656 |
| 20 | Hyperlipoproteinemia (HP:0010980) | 3.09066007 |
| 21 | Torticollis (HP:0000473) | 3.02593705 |
| 22 | Tubulointerstitial abnormality (HP:0001969) | 3.00107025 |
| 23 | Polyuria (HP:0000103) | 2.96714618 |
| 24 | Renal salt wasting (HP:0000127) | 2.94392878 |
| 25 | Genetic anticipation (HP:0003743) | 2.93620231 |
| 26 | Retinal atrophy (HP:0001105) | 2.87573758 |
| 27 | Porencephaly (HP:0002132) | 2.86499621 |
| 28 | Absent speech (HP:0001344) | 2.76157422 |
| 29 | Cutaneous photosensitivity (HP:0000992) | 2.75834815 |
| 30 | Abnormal urine output (HP:0012590) | 2.64957740 |
| 31 | Exertional dyspnea (HP:0002875) | 2.64047863 |
| 32 | Increased muscle lipid content (HP:0009058) | 2.59973605 |
| 33 | Muscle fiber splitting (HP:0003555) | 2.58268177 |
| 34 | Progressive cerebellar ataxia (HP:0002073) | 2.56845014 |
| 35 | Bilateral microphthalmos (HP:0007633) | 2.56127803 |
| 36 | Tubular atrophy (HP:0000092) | 2.55660208 |
| 37 | Abnormality of the renal cortex (HP:0011035) | 2.50921634 |
| 38 | Broad-based gait (HP:0002136) | 2.49334365 |
| 39 | Spastic tetraparesis (HP:0001285) | 2.47470671 |
| 40 | Papillary thyroid carcinoma (HP:0002895) | 2.42136585 |
| 41 | Hyperventilation (HP:0002883) | 2.39667590 |
| 42 | Increased intramyocellular lipid droplets (HP:0012240) | 2.39426684 |
| 43 | Absent hand (HP:0004050) | 2.39395066 |
| 44 | Dysmetric saccades (HP:0000641) | 2.39334207 |
| 45 | Conical tooth (HP:0000698) | 2.36083338 |
| 46 | Hyperkalemia (HP:0002153) | 2.35659831 |
| 47 | Onycholysis (HP:0001806) | 2.32311020 |
| 48 | Abnormality of the axillary hair (HP:0100134) | 2.31134134 |
| 49 | Abnormality of secondary sexual hair (HP:0009888) | 2.31134134 |
| 50 | Malnutrition (HP:0004395) | 2.28159217 |
| 51 | Abnormality of potassium homeostasis (HP:0011042) | 2.28146271 |
| 52 | Periorbital edema (HP:0100539) | 2.25039502 |
| 53 | Xanthomatosis (HP:0000991) | 2.24585400 |
| 54 | Asymmetric septal hypertrophy (HP:0001670) | 2.22432554 |
| 55 | Large for gestational age (HP:0001520) | 2.21430969 |
| 56 | Abnormality of renal excretion (HP:0011036) | 2.19653495 |
| 57 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.18159280 |
| 58 | Increased hepatocellular lipid droplets (HP:0006565) | 2.15464070 |
| 59 | Facial edema (HP:0000282) | 2.14047778 |
| 60 | Blue irides (HP:0000635) | 2.11319879 |
| 61 | Hypokalemia (HP:0002900) | 2.11308414 |
| 62 | Aplasia involving bones of the extremities (HP:0009825) | 2.07056416 |
| 63 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.07056416 |
| 64 | Aplasia of the phalanges of the hand (HP:0009802) | 2.07056416 |
| 65 | Alkalosis (HP:0001948) | 2.06159566 |
| 66 | Febrile seizures (HP:0002373) | 2.05577251 |
| 67 | Ureteral stenosis (HP:0000071) | 2.03082251 |
| 68 | Diminished motivation (HP:0000745) | 2.02973363 |
| 69 | Abnormality of male internal genitalia (HP:0000022) | 1.98706933 |
| 70 | Abnormality of sodium homeostasis (HP:0010931) | 1.97846350 |
| 71 | Skin nodule (HP:0200036) | 1.97637147 |
| 72 | Heart block (HP:0012722) | 1.97501453 |
| 73 | Cerebral inclusion bodies (HP:0100314) | 1.97355919 |
| 74 | Renal Fanconi syndrome (HP:0001994) | 1.96151395 |
| 75 | Craniofacial dystonia (HP:0012179) | 1.94123695 |
| 76 | Renal cell carcinoma (HP:0005584) | 1.92970626 |
| 77 | Adrenal overactivity (HP:0002717) | 1.92599283 |
| 78 | Hyponatremia (HP:0002902) | 1.90745032 |
| 79 | Thin skin (HP:0000963) | 1.89557369 |
| 80 | Focal dystonia (HP:0004373) | 1.89424361 |
| 81 | Hemiplegia (HP:0002301) | 1.89255838 |
| 82 | Acanthosis nigricans (HP:0000956) | 1.88094036 |
| 83 | Hypotrichosis (HP:0001006) | 1.87234281 |
| 84 | Postural instability (HP:0002172) | 1.85204956 |
| 85 | Prostate neoplasm (HP:0100787) | 1.84959681 |
| 86 | Ureteral obstruction (HP:0006000) | 1.84668769 |
| 87 | Palpebral edema (HP:0100540) | 1.84469267 |
| 88 | Type 1 muscle fiber predominance (HP:0003803) | 1.81940201 |
| 89 | Adactyly (HP:0009776) | 1.81904757 |
| 90 | Chest pain (HP:0100749) | 1.80738984 |
| 91 | Limb dystonia (HP:0002451) | 1.80472106 |
| 92 | Bundle branch block (HP:0011710) | 1.80283200 |
| 93 | Type II lissencephaly (HP:0007260) | 1.79032885 |
| 94 | Bronchomalacia (HP:0002780) | 1.78458943 |
| 95 | Death in childhood (HP:0003819) | 1.78153884 |
| 96 | Abnormal atrioventricular conduction (HP:0005150) | 1.76592717 |
| 97 | Lipid accumulation in hepatocytes (HP:0006561) | 1.76180472 |
| 98 | Dry hair (HP:0011359) | 1.75657380 |
| 99 | Progressive microcephaly (HP:0000253) | 1.75404126 |
| 100 | Congenital, generalized hypertrichosis (HP:0004540) | 1.75386089 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CCNB1 | 7.95794192 |
| 2 | NEK2 | 7.19033435 |
| 3 | CAMKK2 | 5.32766245 |
| 4 | CAMK1D | 4.44808916 |
| 5 | CAMK1G | 2.91704849 |
| 6 | TAF1 | 2.49699497 |
| 7 | CAMKK1 | 2.30341858 |
| 8 | SMG1 | 2.27882863 |
| 9 | ERN1 | 2.21456447 |
| 10 | VRK2 | 2.08579991 |
| 11 | CAMK1 | 2.02630978 |
| 12 | LRRK2 | 1.71885438 |
| 13 | MAP3K7 | 1.66461563 |
| 14 | CHUK | 1.55947473 |
| 15 | MAPKAPK5 | 1.44095884 |
| 16 | GRK5 | 1.39124067 |
| 17 | MARK2 | 1.30704140 |
| 18 | TESK1 | 1.30432374 |
| 19 | TESK2 | 1.29279294 |
| 20 | WNK4 | 1.28369712 |
| 21 | MARK1 | 1.22504548 |
| 22 | NTRK3 | 1.15884128 |
| 23 | PHKG2 | 0.98159737 |
| 24 | PHKG1 | 0.98159737 |
| 25 | PNCK | 0.97556966 |
| 26 | MAPK15 | 0.97329026 |
| 27 | OBSCN | 0.95538728 |
| 28 | MAPK4 | 0.95239335 |
| 29 | PRKAA2 | 0.91547274 |
| 30 | TRIB3 | 0.90247858 |
| 31 | MAP3K4 | 0.88224391 |
| 32 | MAPK7 | 0.85269718 |
| 33 | STK24 | 0.82961408 |
| 34 | ABL2 | 0.82404145 |
| 35 | CAMK4 | 0.82364380 |
| 36 | LIMK1 | 0.78406254 |
| 37 | CASK | 0.77467513 |
| 38 | PDGFRB | 0.74444378 |
| 39 | NUAK1 | 0.72457070 |
| 40 | DAPK2 | 0.69964448 |
| 41 | MAP3K10 | 0.68099662 |
| 42 | GRK1 | 0.65374884 |
| 43 | TIE1 | 0.63418363 |
| 44 | MAPK12 | 0.63294955 |
| 45 | PAK2 | 0.63193754 |
| 46 | PKN1 | 0.55091518 |
| 47 | DYRK1A | 0.52004875 |
| 48 | HIPK2 | 0.49822522 |
| 49 | FRK | 0.48590654 |
| 50 | VRK1 | 0.45633454 |
| 51 | PRKG1 | 0.45225354 |
| 52 | PRKD1 | 0.44779350 |
| 53 | NTRK2 | 0.44701578 |
| 54 | CSK | 0.43057324 |
| 55 | PINK1 | 0.42424928 |
| 56 | PRKAA1 | 0.40870892 |
| 57 | MELK | 0.40039359 |
| 58 | MAP2K4 | 0.38559953 |
| 59 | PRKCG | 0.38338760 |
| 60 | CAMK2B | 0.38063207 |
| 61 | DDR2 | 0.36472954 |
| 62 | DAPK1 | 0.32655966 |
| 63 | EIF2AK2 | 0.31918966 |
| 64 | PRKCE | 0.31650195 |
| 65 | LATS2 | 0.30944271 |
| 66 | EPHA4 | 0.30092559 |
| 67 | MAPK13 | 0.28795288 |
| 68 | CAMK2A | 0.28786818 |
| 69 | RIPK1 | 0.28460816 |
| 70 | PAK3 | 0.28172149 |
| 71 | CDK9 | 0.28125736 |
| 72 | ADRBK1 | 0.27376689 |
| 73 | SGK2 | 0.26638770 |
| 74 | PRKCH | 0.26431525 |
| 75 | PAK6 | 0.25455354 |
| 76 | CDK5 | 0.22805805 |
| 77 | TTN | 0.22722339 |
| 78 | WNK1 | 0.22707882 |
| 79 | SGK1 | 0.21663853 |
| 80 | PRPF4B | 0.21438945 |
| 81 | SYK | 0.21366215 |
| 82 | ACVR1B | 0.20857509 |
| 83 | DAPK3 | 0.20715445 |
| 84 | TYRO3 | 0.20558238 |
| 85 | STK38L | 0.20383022 |
| 86 | IKBKE | 0.20274359 |
| 87 | PRKD3 | 0.19993933 |
| 88 | MAP2K7 | 0.19532551 |
| 89 | MYLK | 0.19494969 |
| 90 | PIK3CG | 0.19402672 |
| 91 | PRKCA | 0.18762059 |
| 92 | PRKACA | 0.18049886 |
| 93 | MAPK10 | 0.17331274 |
| 94 | PRKCI | 0.17000417 |
| 95 | KSR2 | 0.15856525 |
| 96 | SIK2 | 0.15764267 |
| 97 | CAMK2D | 0.14974085 |
| 98 | TGFBR1 | 0.14098709 |
| 99 | PTK2B | 0.13491467 |
| 100 | PIK3CA | 0.13117942 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Histidine metabolism_Homo sapiens_hsa00340 | 3.26660623 |
| 2 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.94968710 |
| 3 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 2.83782102 |
| 4 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 2.67075096 |
| 5 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.57604461 |
| 6 | Nicotine addiction_Homo sapiens_hsa05033 | 2.38193504 |
| 7 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 2.30181338 |
| 8 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.90234692 |
| 9 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.89671062 |
| 10 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.78430556 |
| 11 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.76695432 |
| 12 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.74820366 |
| 13 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.72264502 |
| 14 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.71166948 |
| 15 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.63876205 |
| 16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.63110570 |
| 17 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.58592903 |
| 18 | Circadian entrainment_Homo sapiens_hsa04713 | 1.56552929 |
| 19 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.56120392 |
| 20 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.54539525 |
| 21 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.49879846 |
| 22 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.49195944 |
| 23 | Morphine addiction_Homo sapiens_hsa05032 | 1.45225568 |
| 24 | GABAergic synapse_Homo sapiens_hsa04727 | 1.43284742 |
| 25 | Taste transduction_Homo sapiens_hsa04742 | 1.41044799 |
| 26 | Renin secretion_Homo sapiens_hsa04924 | 1.40549409 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.38185928 |
| 28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.31061242 |
| 29 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.27611466 |
| 30 | Cocaine addiction_Homo sapiens_hsa05030 | 1.19914210 |
| 31 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.19793501 |
| 32 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.15342553 |
| 33 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.11333871 |
| 34 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.11112141 |
| 35 | Long-term depression_Homo sapiens_hsa04730 | 1.10928190 |
| 36 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.10780350 |
| 37 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.06792988 |
| 38 | Salivary secretion_Homo sapiens_hsa04970 | 1.04058946 |
| 39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03814471 |
| 40 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.03386831 |
| 41 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.00284143 |
| 42 | Olfactory transduction_Homo sapiens_hsa04740 | 0.99284382 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.99204816 |
| 44 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.98494084 |
| 45 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.97394928 |
| 46 | Insulin secretion_Homo sapiens_hsa04911 | 0.96984582 |
| 47 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.93833905 |
| 48 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.93112373 |
| 49 | Phagosome_Homo sapiens_hsa04145 | 0.90094857 |
| 50 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.89970295 |
| 51 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.89743960 |
| 52 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.86541691 |
| 53 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.83405827 |
| 54 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.81337670 |
| 55 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.80094834 |
| 56 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.79914518 |
| 57 | Axon guidance_Homo sapiens_hsa04360 | 0.78754758 |
| 58 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.78301891 |
| 59 | Gap junction_Homo sapiens_hsa04540 | 0.76698321 |
| 60 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.73629223 |
| 61 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.72989099 |
| 62 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.71739128 |
| 63 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.69460948 |
| 64 | ABC transporters_Homo sapiens_hsa02010 | 0.68420004 |
| 65 | Lysosome_Homo sapiens_hsa04142 | 0.67250346 |
| 66 | Basal transcription factors_Homo sapiens_hsa03022 | 0.66945292 |
| 67 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.66213862 |
| 68 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.65429822 |
| 69 | Lysine degradation_Homo sapiens_hsa00310 | 0.65103168 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.64486725 |
| 71 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64485661 |
| 72 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.63844084 |
| 73 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.63818286 |
| 74 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.62353750 |
| 75 | Bile secretion_Homo sapiens_hsa04976 | 0.62128955 |
| 76 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.62083011 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.59256020 |
| 78 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.57141529 |
| 79 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.56839261 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56182830 |
| 81 | Amoebiasis_Homo sapiens_hsa05146 | 0.55898599 |
| 82 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.55012938 |
| 83 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.54789435 |
| 84 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.51537664 |
| 85 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.47121883 |
| 86 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.46722923 |
| 87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.46656531 |
| 88 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.44629902 |
| 89 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.44201629 |
| 90 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.43496915 |
| 91 | Melanogenesis_Homo sapiens_hsa04916 | 0.43434869 |
| 92 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.43414440 |
| 93 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.41724638 |
| 94 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.40835941 |
| 95 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.40775997 |
| 96 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.40721375 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38078220 |
| 98 | Circadian rhythm_Homo sapiens_hsa04710 | 0.37439880 |
| 99 | Platelet activation_Homo sapiens_hsa04611 | 0.37023740 |
| 100 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.36600339 |

