RETNLB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal epithelial cell development (GO:0060576)8.72685418
2epithelial structure maintenance (GO:0010669)8.65384371
3angiotensin maturation (GO:0002003)8.26049315
4regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)7.65890544
5O-glycan processing (GO:0016266)6.86806444
6regulation of guanylate cyclase activity (GO:0031282)6.79806093
7sulfur amino acid catabolic process (GO:0000098)6.41651586
8bundle of His cell to Purkinje myocyte communication (GO:0086069)6.38286558
9sulfation (GO:0051923)6.19821234
10lung secretory cell differentiation (GO:0061140)6.03235149
11regulation of cellular extravasation (GO:0002691)6.02649884
12positive regulation of respiratory burst (GO:0060267)5.77854150
13antibacterial humoral response (GO:0019731)5.46239787
14positive regulation of guanylate cyclase activity (GO:0031284)5.36423600
15lipoprotein transport (GO:0042953)5.32432067
16NADH metabolic process (GO:0006734)5.31048468
17intestinal absorption (GO:0050892)5.27142579
18regulation of systemic arterial blood pressure by hormone (GO:0001990)5.24600959
19regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.24600959
20endocrine process (GO:0050886)5.24600959
21antimicrobial humoral response (GO:0019730)5.21321989
22actin filament depolymerization (GO:0030042)4.99677194
23transcytosis (GO:0045056)4.98762248
24positive regulation of pseudopodium assembly (GO:0031274)4.98602569
25nucleotide-sugar metabolic process (GO:0009225)4.82800159
26sulfate transmembrane transport (GO:1902358)4.80404825
27nucleotide-sugar biosynthetic process (GO:0009226)4.78484150
28regulation of vitamin metabolic process (GO:0030656)4.70661132
29epoxygenase P450 pathway (GO:0019373)4.67448061
30regulation of systemic arterial blood pressure (GO:0003073)4.63473854
31digestive system process (GO:0022600)4.62708343
32bile acid and bile salt transport (GO:0015721)4.58171387
33glomerular filtration (GO:0003094)4.57891487
34urea cycle (GO:0000050)4.50182288
35glandular epithelial cell differentiation (GO:0002067)4.47717198
36regulation of pseudopodium assembly (GO:0031272)4.47099767
37pyrimidine-containing compound transmembrane transport (GO:0072531)4.44513048
38protein O-linked glycosylation (GO:0006493)4.40132798
39fat-soluble vitamin biosynthetic process (GO:0042362)4.38308374
40striated muscle atrophy (GO:0014891)4.37059153
41eosinophil chemotaxis (GO:0048245)4.30718546
42receptor guanylyl cyclase signaling pathway (GO:0007168)4.29071131
43regulation of cholesterol homeostasis (GO:2000188)4.27453739
44purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.27071892
453-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.27071892
46detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)4.24133579
47bicarbonate transport (GO:0015701)4.20368373
48urea metabolic process (GO:0019627)4.18941907
49renal filtration (GO:0097205)4.14997123
50amino sugar metabolic process (GO:0006040)4.13542214
51flavonoid metabolic process (GO:0009812)4.12753749
52regulation of cGMP biosynthetic process (GO:0030826)4.11821527
53hormone catabolic process (GO:0042447)4.01193553
54positive regulation of glycoprotein biosynthetic process (GO:0010560)3.97035834
55virion attachment to host cell (GO:0019062)3.87926507
56adhesion of symbiont to host cell (GO:0044650)3.87926507
57nitrogen cycle metabolic process (GO:0071941)3.84793983
58vitamin transmembrane transport (GO:0035461)3.84666132
59sperm capacitation (GO:0048240)3.84085759
60eosinophil migration (GO:0072677)3.83834860
61skeletal muscle adaptation (GO:0043501)3.82783623
62sulfate transport (GO:0008272)3.79179537
63galactose catabolic process (GO:0019388)3.78923298
64digestion (GO:0007586)3.73572698
65regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.73081332
66positive regulation of epidermal cell differentiation (GO:0045606)3.68077766
67glycosphingolipid catabolic process (GO:0046479)3.67583480
68glycolipid catabolic process (GO:0019377)3.65844871
69oligosaccharide biosynthetic process (GO:0009312)3.63234970
70positive regulation of glycoprotein metabolic process (GO:1903020)3.62615280
71antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.60997886
72diacylglycerol metabolic process (GO:0046339)3.60432660
73arginine metabolic process (GO:0006525)3.59992719
74drug metabolic process (GO:0017144)3.59573934
75cellular glucuronidation (GO:0052695)3.57059484
76muscle atrophy (GO:0014889)3.55863846
77vitamin A metabolic process (GO:0006776)3.51758907
78ethanol oxidation (GO:0006069)3.50449715
79fructose metabolic process (GO:0006000)3.50044234
80L-fucose catabolic process (GO:0042355)3.49108334
81fucose catabolic process (GO:0019317)3.49108334
82L-fucose metabolic process (GO:0042354)3.49108334
83sialylation (GO:0097503)3.48312863
84ventricular cardiac muscle cell action potential (GO:0086005)3.47682443
85N-acetylglucosamine metabolic process (GO:0006044)3.44990064
86cell communication involved in cardiac conduction (GO:0086065)3.44618967
87antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.42410606
88glycosylceramide metabolic process (GO:0006677)3.40482232
89glucosamine-containing compound metabolic process (GO:1901071)3.39129983
90peptide hormone processing (GO:0016486)3.39039273
91hypotonic response (GO:0006971)3.38795056
92GDP-mannose metabolic process (GO:0019673)3.37851819
93regulation of cGMP metabolic process (GO:0030823)3.37511035
94complement activation, classical pathway (GO:0006958)3.36249113
95sulfur compound transport (GO:0072348)3.30977578
96vocalization behavior (GO:0071625)3.26973891
97lung cell differentiation (GO:0060479)3.25198754
98epithelial cell-cell adhesion (GO:0090136)3.24110805
99adhesion of symbiont to host (GO:0044406)3.23659450
100positive regulation of actin filament depolymerization (GO:0030836)3.22967314
101midgut development (GO:0007494)3.22324808
102negative regulation of cell fate commitment (GO:0010454)3.22239717
103membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.19301981
104fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.18901413
105uronic acid metabolic process (GO:0006063)3.18756094
106glucuronate metabolic process (GO:0019585)3.18756094
107antigen processing and presentation of endogenous antigen (GO:0019883)3.18643702
108lipopolysaccharide biosynthetic process (GO:0009103)3.18453815
109membrane hyperpolarization (GO:0060081)3.18323390
110positive regulation of fatty acid beta-oxidation (GO:0032000)3.16634356
111regulation of respiratory burst (GO:0060263)3.16157894
112cardiac conduction (GO:0061337)3.14616110
113cGMP-mediated signaling (GO:0019934)3.14170740
114auditory receptor cell differentiation (GO:0042491)3.13948303
115renal system process involved in regulation of blood volume (GO:0001977)3.12606154
116drug transmembrane transport (GO:0006855)3.11825071
117lung epithelial cell differentiation (GO:0060487)3.11419874
118peptide catabolic process (GO:0043171)3.10604476
119sodium ion export (GO:0071436)3.09993111
120positive regulation of cGMP biosynthetic process (GO:0030828)3.09310861
121renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.08028640
122drug catabolic process (GO:0042737)3.05974773
123neurotransmitter biosynthetic process (GO:0042136)3.04893886
124neuron fate determination (GO:0048664)3.04143224
125citrulline biosynthetic process (GO:0019240)3.02740054
126bile acid metabolic process (GO:0008206)3.02739523
127regulation of bile acid biosynthetic process (GO:0070857)3.02127945
128homocysteine metabolic process (GO:0050667)3.01978565
129exogenous drug catabolic process (GO:0042738)3.01522843
130hemidesmosome assembly (GO:0031581)3.01133862
131nucleoside diphosphate biosynthetic process (GO:0009133)3.00075297
132regulation of pH (GO:0006885)2.97931032
133drug transport (GO:0015893)2.96006915
134thrombin receptor signaling pathway (GO:0070493)2.94877395
135glutamine family amino acid biosynthetic process (GO:0009084)2.93540565
136ceramide catabolic process (GO:0046514)2.93272443
137cytoskeletal anchoring at plasma membrane (GO:0007016)2.92124814
138phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.91804160
139positive regulation of epidermis development (GO:0045684)2.91692179
140citrulline metabolic process (GO:0000052)2.90898604
141mRNA modification (GO:0016556)2.89796005
142regulation of protein glycosylation (GO:0060049)2.89047435
143very-low-density lipoprotein particle assembly (GO:0034379)2.87770818
144galactose metabolic process (GO:0006012)2.86833265
145columnar/cuboidal epithelial cell development (GO:0002066)2.86791732
146calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.86463050
147chloride transmembrane transport (GO:1902476)2.83050891
148desmosome organization (GO:0002934)2.80397511
149membrane repolarization during action potential (GO:0086011)2.78406130
150regulation of heart rate by cardiac conduction (GO:0086091)2.74474725
151hepatocyte apoptotic process (GO:0097284)2.73811151
152ethanol metabolic process (GO:0006067)2.73129415
153cellular ketone body metabolic process (GO:0046950)2.72663355
154N-acetylneuraminate metabolic process (GO:0006054)2.71198281
155lipopolysaccharide metabolic process (GO:0008653)2.69035074
156regulation of intracellular pH (GO:0051453)2.66887678
157glucocorticoid biosynthetic process (GO:0006704)2.64427738
158inorganic anion transmembrane transport (GO:0098661)2.63618517
159negative regulation of keratinocyte proliferation (GO:0010839)2.61951402
160production of molecular mediator of immune response (GO:0002440)2.61626526
161keratinocyte proliferation (GO:0043616)2.61456543
162leukocyte tethering or rolling (GO:0050901)2.61209711
163phospholipid scrambling (GO:0017121)2.59337057
164cellular response to hepatocyte growth factor stimulus (GO:0035729)2.58248430
165response to hepatocyte growth factor (GO:0035728)2.58248430
166maintenance of gastrointestinal epithelium (GO:0030277)11.0827632
167UDP-N-acetylglucosamine metabolic process (GO:0006047)10.8618055

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.26972054
2CDX2_20551321_ChIP-Seq_CACO-2_Human4.82147683
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.31551672
4* SOX2_27498859_Chip-Seq_STOMACH_Mouse3.44890834
5RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.14461636
6CDX2_19796622_ChIP-Seq_MESCs_Mouse3.09793770
7IRF8_22096565_ChIP-ChIP_GC-B_Human2.90072336
8SOX2_20726797_ChIP-Seq_SW620_Human2.85296490
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.51736938
10PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.48506098
11GATA6_25053715_ChIP-Seq_YYC3_Human2.41878105
12* GATA4_25053715_ChIP-Seq_YYC3_Human2.39232331
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.38920131
14ESR2_21235772_ChIP-Seq_MCF-7_Human2.29100660
15ESR1_20079471_ChIP-ChIP_T-47D_Human2.28275486
16DROSHA_22980978_ChIP-Seq_HELA_Human2.22915203
17SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.17555250
18PPARA_22158963_ChIP-Seq_LIVER_Mouse2.14443612
19EGR1_23403033_ChIP-Seq_LIVER_Mouse2.10149285
20RXR_22158963_ChIP-Seq_LIVER_Mouse2.01932743
21TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.01147641
22STAT6_21828071_ChIP-Seq_BEAS2B_Human2.00497709
23LXR_22158963_ChIP-Seq_LIVER_Mouse1.90013447
24* FOXO3_23340844_ChIP-Seq_DLD1_Human1.85264462
25TRIM28_21343339_ChIP-Seq_HEK293_Human1.84961234
26HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.82179579
27ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.81010635
28PPAR_26484153_Chip-Seq_NCI-H1993_Human1.80004164
29RACK7_27058665_Chip-Seq_MCF-7_Human1.79363156
30* RUNX1_27514584_Chip-Seq_MCF-7_Human1.75500943
31TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.73538276
32ESR1_21235772_ChIP-Seq_MCF-7_Human1.70785097
33ZNF263_19887448_ChIP-Seq_K562_Human1.66814047
34ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.66493621
35FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.65226866
36SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.65043981
37TCF4_18268006_ChIP-ChIP_LS174T_Human1.60347394
38KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.58859582
39KLF5_25053715_ChIP-Seq_YYC3_Human1.58828848
40KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.57964043
41ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.53542585
42RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.52497304
43BCAT_22108803_ChIP-Seq_LS180_Human1.49909186
44ZNF217_24962896_ChIP-Seq_MCF-7_Human1.48984267
45NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.48522053
46FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.45586032
47STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.35382499
48GATA2_19941826_ChIP-Seq_K562_Human1.31657260
49BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.31536670
50IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28274109
51CREB1_26743006_Chip-Seq_LNCaP_Human1.28036084
52CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.26803141
53THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.26617166
54KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24994672
55MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.24745775
56EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.23721749
57KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.21153253
58KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.21153253
59KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.21153253
60FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.20840801
61CLOCK_20551151_ChIP-Seq_293T_Human1.20808545
62AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.19441315
63VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16537991
64NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.16503654
65FOXM1_26456572_ChIP-Seq_MCF-7_Human1.16477286
66ATF3_27146783_Chip-Seq_COLON_Human1.16345031
67LXR_22292898_ChIP-Seq_THP-1_Human1.15432196
68CEBPB_22108803_ChIP-Seq_LS180_Human1.13420656
69IRF8_21731497_ChIP-ChIP_J774_Mouse1.13403987
70EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12205615
71CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.10704164
72PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.08732937
73FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.07425266
74CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07283446
75RARG_19884340_ChIP-ChIP_MEFs_Mouse1.06623063
76AR_21909140_ChIP-Seq_LNCAP_Human1.05942422
77* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.04747593
78STAT1_20625510_ChIP-Seq_HELA_Human1.02943142
79ELK3_25401928_ChIP-Seq_HUVEC_Human1.02370184
80SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.00893942
81NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.99924880
82BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.99890609
83GATA1_19941826_ChIP-Seq_K562_Human0.97815194
84RXR_22108803_ChIP-Seq_LS180_Human0.97638218
85SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.96984759
86SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.96984759
87FOXA1_25552417_ChIP-Seq_VCAP_Human0.96557540
88JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.96154158
89FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.94498703
90SA1_27219007_Chip-Seq_Bcells_Human0.93549599
91HIF1A_21447827_ChIP-Seq_MCF-7_Human0.92728191
92SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92556486
93CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91907487
94CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91721511
95CDX2_22108803_ChIP-Seq_LS180_Human0.91516835
96JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.91413143
97AHR_22903824_ChIP-Seq_MCF-7_Human0.91139827
98FOXA2_19822575_ChIP-Seq_HepG2_Human0.91122989
99GATA1_22025678_ChIP-Seq_K562_Human0.90617049
100CTNNB1_20460455_ChIP-Seq_HCT116_Human0.88812703
101GATA2_22383799_ChIP-Seq_G1ME_Mouse0.88493963
102NANOG_20526341_ChIP-Seq_ESCs_Human0.88145560
103GATA3_24758297_ChIP-Seq_MCF-7_Human0.87920460
104UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.87893046
105TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86192108
106PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.85590399
107P300_27058665_Chip-Seq_ZR-75-30cells_Human0.84869093
108HNF4A_19822575_ChIP-Seq_HepG2_Human0.84785870
109PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.84022508
110CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.83743788
111CJUN_26792858_Chip-Seq_BT549_Human0.83247835
112CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.83197426
113EGR1_19032775_ChIP-ChIP_M12_Human0.83186703
114* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.82825608
115MYC_19915707_ChIP-ChIP_AK7_Human0.82205055
116ELF5_23300383_ChIP-Seq_T47D_Human0.81888388
117P63_26484246_Chip-Seq_KERATINOCYTES_Human0.81473033
118TET1_21451524_ChIP-Seq_MESCs_Mouse0.80897118
119SMAD_19615063_ChIP-ChIP_OVARY_Human0.80717353
120NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.80693732
121FOXA1_21572438_ChIP-Seq_LNCaP_Human0.80424852
122Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.79370092
123TP53_16413492_ChIP-PET_HCT116_Human0.78922484
124SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.78046456
125NR3C1_21868756_ChIP-Seq_MCF10A_Human0.77833029
126MTF2_20144788_ChIP-Seq_MESCs_Mouse0.77683912
127BCL6_27268052_Chip-Seq_Bcells_Human0.77562616
128SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.77092553
129IRF8_27001747_Chip-Seq_BMDM_Mouse0.75503938
130SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.75371600
131KAP1_22055183_ChIP-Seq_ESCs_Mouse0.74267982
132RAD21_21589869_ChIP-Seq_MESCs_Mouse0.73022928
133TP63_23658742_ChIP-Seq_EP156T_Human0.72403077
134OCT4_18692474_ChIP-Seq_MEFs_Mouse0.71704903
135BCOR_27268052_Chip-Seq_Bcells_Human0.71314701

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003866_abnormal_defecation5.89852380
2MP0010234_abnormal_vibrissa_follicle5.60188181
3MP0002822_catalepsy3.88794466
4* MP0001663_abnormal_digestive_system3.85856580
5MP0003183_abnormal_peptide_metabolism3.84183280
6* MP0010155_abnormal_intestine_physiology3.52510038
7* MP0005381_digestive/alimentary_phenotyp3.51758861
8MP0001666_abnormal_nutrient_absorption3.45487706
9MP0004264_abnormal_extraembryonic_tissu3.38316589
10MP0000462_abnormal_digestive_system3.31938341
11MP0010352_gastrointestinal_tract_polyps3.27660870
12MP0004043_abnormal_pH_regulation3.23118484
13MP0001873_stomach_inflammation3.15061303
14MP0000490_abnormal_crypts_of3.04921966
15MP0003705_abnormal_hypodermis_morpholog3.04885581
16MP0000465_gastrointestinal_hemorrhage2.95218296
17MP0005377_hearing/vestibular/ear_phenot2.69637258
18MP0003878_abnormal_ear_physiology2.69637258
19MP0001664_abnormal_digestion2.65700973
20MP0006054_spinal_hemorrhage2.65505118
21* MP0000477_abnormal_intestine_morphology2.65022549
22MP0005167_abnormal_blood-brain_barrier2.60650867
23MP0005085_abnormal_gallbladder_physiolo2.55569316
24MP0003283_abnormal_digestive_organ2.51259019
25MP0003300_gastrointestinal_ulcer2.43596157
26MP0000537_abnormal_urethra_morphology2.29283359
27MP0005360_urolithiasis2.17068734
28MP0008875_abnormal_xenobiotic_pharmacok2.05776807
29MP0003868_abnormal_feces_composition2.04505975
30MP0005409_darkened_coat_color1.87939992
31MP0005365_abnormal_bile_salt1.86859536
32MP0000467_abnormal_esophagus_morphology1.83263638
33MP0003252_abnormal_bile_duct1.80433413
34MP0002277_abnormal_respiratory_mucosa1.64165313
35MP0001765_abnormal_ion_homeostasis1.59877489
36MP0004782_abnormal_surfactant_physiolog1.54938947
37MP0003806_abnormal_nucleotide_metabolis1.51182081
38MP0008004_abnormal_stomach_pH1.48938389
39MP0004858_abnormal_nervous_system1.44056185
40MP0001849_ear_inflammation1.39603185
41MP0002139_abnormal_hepatobiliary_system1.38763088
42MP0002138_abnormal_hepatobiliary_system1.37445406
43MP0005332_abnormal_amino_acid1.30241919
44MP0002796_impaired_skin_barrier1.27909203
45MP0009379_abnormal_foot_pigmentation1.26466771
46MP0001764_abnormal_homeostasis1.26219318
47MP0000470_abnormal_stomach_morphology1.25610689
48MP0003724_increased_susceptibility_to1.24847971
49MP0000538_abnormal_urinary_bladder1.23150204
50MP0005670_abnormal_white_adipose1.21964646
51MP0010329_abnormal_lipoprotein_level1.10816139
52MP0010678_abnormal_skin_adnexa1.08747692
53MP0005310_abnormal_salivary_gland1.07311238
54MP0001501_abnormal_sleep_pattern1.07083095
55MP0009643_abnormal_urine_homeostasis1.06294158
56MP0005636_abnormal_mineral_homeostasis1.05556876
57MP0001188_hyperpigmentation1.05509732
58MP0003091_abnormal_cell_migration1.00001081
59MP0004185_abnormal_adipocyte_glucose0.93890649
60MP0004147_increased_porphyrin_level0.92700135
61MP0003453_abnormal_keratinocyte_physiol0.92050964
62MP0001790_abnormal_immune_system0.89674783
63MP0005387_immune_system_phenotype0.89674783
64MP0009780_abnormal_chondrocyte_physiolo0.87233619
65MP0005584_abnormal_enzyme/coenzyme_acti0.86399983
66MP0006082_CNS_inflammation0.86043155
67MP0003566_abnormal_cell_adhesion0.85314769
68MP0005257_abnormal_intraocular_pressure0.80633057
69MP0005448_abnormal_energy_balance0.80456347
70MP0004484_altered_response_of0.79828052
71MP0003045_fibrosis0.78961304
72MP0000013_abnormal_adipose_tissue0.78294871
73MP0005187_abnormal_penis_morphology0.78147346
74MP0008872_abnormal_physiological_respon0.77237547
75* MP0005025_abnormal_response_to0.77047236
76MP0005165_increased_susceptibility_to0.76678418
77* MP0005166_decreased_susceptibility_to0.76325464
78MP0002837_dystrophic_cardiac_calcinosis0.75440872
79MP0002060_abnormal_skin_morphology0.75307632
80MP0005501_abnormal_skin_physiology0.75191343
81MP0000230_abnormal_systemic_arterial0.74696543
82MP0001485_abnormal_pinna_reflex0.73291947
83MP0002971_abnormal_brown_adipose0.71675238
84MP0003329_amyloid_beta_deposits0.70766347
85MP0003303_peritoneal_inflammation0.70196318
86MP0000003_abnormal_adipose_tissue0.69422147
87MP0002098_abnormal_vibrissa_morphology0.69298426
88MP0002009_preneoplasia0.68657374
89MP0004947_skin_inflammation0.68161548
90MP0001835_abnormal_antigen_presentation0.67020091
91MP0001440_abnormal_grooming_behavior0.66570737
92MP0009115_abnormal_fat_cell0.66368495
93MP0003879_abnormal_hair_cell0.65897757
94MP0001756_abnormal_urination0.65368134
95MP0008469_abnormal_protein_level0.64361296
96MP0003718_maternal_effect0.61340789
97MP0003191_abnormal_cellular_cholesterol0.60373416
98MP0002896_abnormal_bone_mineralization0.59596422
99MP0001216_abnormal_epidermal_layer0.59593525
100MP0000249_abnormal_blood_vessel0.59202070
101MP0005319_abnormal_enzyme/_coenzyme0.58642659
102MP0000604_amyloidosis0.58472820
103MP0009642_abnormal_blood_homeostasis0.58298745
104MP0009333_abnormal_splenocyte_physiolog0.57685008
105MP0003436_decreased_susceptibility_to0.57092270
106MP0005535_abnormal_body_temperature0.56732680
107MP0003075_altered_response_to0.56637346
108MP0002148_abnormal_hypersensitivity_rea0.56123999
109MP0008873_increased_physiological_sensi0.55525073
110* MP0001845_abnormal_inflammatory_respons0.55394731
111MP0002118_abnormal_lipid_homeostasis0.54117781
112MP0010386_abnormal_urinary_bladder0.53835982
113MP0002909_abnormal_adrenal_gland0.53293659
114MP0004130_abnormal_muscle_cell0.53267653
115MP0005451_abnormal_body_composition0.53149116
116MP0002136_abnormal_kidney_physiology0.52292953
117MP0000609_abnormal_liver_physiology0.52217110
118MP0000613_abnormal_salivary_gland0.51153587
119MP0002396_abnormal_hematopoietic_system0.51003990
120MP0009384_cardiac_valve_regurgitation0.50889916
121MP0001533_abnormal_skeleton_physiology0.50635337
122MP0004019_abnormal_vitamin_homeostasis0.50110207
123MP0002876_abnormal_thyroid_physiology0.45055916
124MP0004270_analgesia0.44606937
125MP0010771_integument_phenotype0.44210151
126MP0005666_abnormal_adipose_tissue0.44165880
127MP0002006_tumorigenesis0.44067611
128MP0002166_altered_tumor_susceptibility0.43739799
129MP0005058_abnormal_lysosome_morphology0.41437190
130MP0000762_abnormal_tongue_morphology0.40769565
131MP0005375_adipose_tissue_phenotype0.40317327
132MP0003315_abnormal_perineum_morphology0.37407746
133MP0009785_altered_susceptibility_to0.36558995
134MP0000678_abnormal_parathyroid_gland0.35945959
135MP0009840_abnormal_foam_cell0.35661560

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)7.41078466
2Right ventricular cardiomyopathy (HP:0011663)7.18178917
3Hyperactive renin-angiotensin system (HP:0000841)6.90075156
4Metabolic alkalosis (HP:0200114)6.82483297
5Hydroxyprolinuria (HP:0003080)4.89562223
6Abnormality of proline metabolism (HP:0010907)4.89562223
7Abdominal distention (HP:0003270)4.88955911
8Abnormality of chloride homeostasis (HP:0011422)4.79717650
9Abnormality of renin-angiotensin system (HP:0000847)4.52279167
10Flat acetabular roof (HP:0003180)4.52191820
11Mildly elevated creatine phosphokinase (HP:0008180)4.45781816
12Malnutrition (HP:0004395)4.20223097
13Abnormality of the vitamin B12 metabolism (HP:0004341)4.09599272
14Systemic lupus erythematosus (HP:0002725)3.93199277
15Abnormality of the 1st metacarpal (HP:0010009)3.85621778
16Abnormality of vitamin B metabolism (HP:0004340)3.80097132
17Gastrointestinal dysmotility (HP:0002579)3.79520901
18Hypobetalipoproteinemia (HP:0003563)3.77475354
19Abnormal tarsal ossification (HP:0008369)3.77325084
20Aortic aneurysm (HP:0004942)3.75724967
21Acanthocytosis (HP:0001927)3.74765119
22Decreased circulating renin level (HP:0003351)3.62480898
23Widely patent fontanelles and sutures (HP:0004492)3.38177927
24Petechiae (HP:0000967)3.24126628
25Hyperaldosteronism (HP:0000859)3.23549068
26Alkalosis (HP:0001948)3.21042146
27Abnormal foot bone ossification (HP:0010675)3.18849854
28Progressive sensorineural hearing impairment (HP:0000408)3.17674030
29Abnormality of the distal phalanx of the thumb (HP:0009617)3.14192811
30Chronic diarrhea (HP:0002028)3.11556954
31Abnormality of vitamin metabolism (HP:0100508)3.08486936
32Bundle branch block (HP:0011710)3.04407165
33Palpitations (HP:0001962)3.03245911
34Syncope (HP:0001279)3.00964650
35Confusion (HP:0001289)2.85569979
36Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.84054917
37Short 1st metacarpal (HP:0010034)2.84054917
38Pigmentary retinal degeneration (HP:0001146)2.83816157
39Ventricular fibrillation (HP:0001663)2.80208463
40Eczematoid dermatitis (HP:0000976)2.80153212
41Abnormality of carpal bone ossification (HP:0006257)2.77514577
42Intrahepatic cholestasis (HP:0001406)2.76904770
43Hyperparathyroidism (HP:0000843)2.76104740
44Glycosuria (HP:0003076)2.73806401
45Abnormality of urine glucose concentration (HP:0011016)2.73806401
46Ventricular tachycardia (HP:0004756)2.71492593
47Aortic dissection (HP:0002647)2.71272800
48Hemorrhage of the eye (HP:0011885)2.68758308
49Hyperammonemia (HP:0001987)2.68419625
50Pili torti (HP:0003777)2.67674179
51Conjugated hyperbilirubinemia (HP:0002908)2.65356237
52Abnormal cartilage morphology (HP:0002763)2.63626739
53Flattened epiphyses (HP:0003071)2.59724289
54Short phalanx of the thumb (HP:0009660)2.59684212
55Thin bony cortex (HP:0002753)2.55859117
56Hoarse voice (HP:0001609)2.55028353
57Limb-girdle muscle atrophy (HP:0003797)2.54986394
58Wide cranial sutures (HP:0010537)2.54788768
59Pustule (HP:0200039)2.52776676
60Rectal prolapse (HP:0002035)2.51953644
61Hypokalemia (HP:0002900)2.51513776
62Protuberant abdomen (HP:0001538)2.51111206
63Progressive hearing impairment (HP:0001730)2.50008708
64Abnormality of small intestinal villus morphology (HP:0011472)2.49368387
65Villous atrophy (HP:0011473)2.49368387
66Proximal tubulopathy (HP:0000114)2.46959240
67Nephrolithiasis (HP:0000787)2.40708422
68Nausea (HP:0002018)2.39773346
69Hypotension (HP:0002615)2.39617768
70Spinal cord compression (HP:0002176)2.35972777
71Dehydration (HP:0001944)2.35143789
72Focal segmental glomerulosclerosis (HP:0000097)2.33786081
73Abnormality of the 2nd finger (HP:0004100)2.33140277
74Neonatal short-limb short stature (HP:0008921)2.32531840
75Abnormality of monocarboxylic acid metabolism (HP:0010996)2.32394280
76Enlarged epiphyses (HP:0010580)2.31272057
77Vertebral clefting (HP:0008428)2.28491020
78Glomerulonephritis (HP:0000099)2.27040419
79Symphalangism affecting the phalanges of the hand (HP:0009773)2.26916272
80Abnormal ossification of hand bones (HP:0005921)2.26466745
81Woolly hair (HP:0002224)2.25022108
82Abnormal vertebral ossification (HP:0100569)2.23655009
83Ureteral stenosis (HP:0000071)2.21344355
84Hyponatremia (HP:0002902)2.20446955
85Abnormality of dicarboxylic acid metabolism (HP:0010995)2.19944418
86Dicarboxylic aciduria (HP:0003215)2.19944418
87Abnormal biliary tract morphology (HP:0012440)2.19615960
88Abnormality of complement system (HP:0005339)2.18747814
89Steatorrhea (HP:0002570)2.17432488
90Nephritis (HP:0000123)2.17343915
91Hyperkalemia (HP:0002153)2.16342615
92Hyperuricemia (HP:0002149)2.15857528
93Increased purine levels (HP:0004368)2.15857528
94Xanthomatosis (HP:0000991)2.15409396
95Micronodular cirrhosis (HP:0001413)2.15141772
96Biliary tract neoplasm (HP:0100574)2.14689689
97Renal tubular acidosis (HP:0001947)2.12685191
98Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.10809197
99Vertebral hypoplasia (HP:0008417)2.10809197
100Congenital sensorineural hearing impairment (HP:0008527)2.09996706
101Cerebral palsy (HP:0100021)2.08050339
102Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.06694112
103Abnormality of potassium homeostasis (HP:0011042)2.06243003
104Complement deficiency (HP:0004431)2.05695624
105Cone-rod dystrophy (HP:0000548)2.05388398
106Abnormal hand bone ossification (HP:0010660)2.05150784
107Abnormality of glutamine family amino acid metabolism (HP:0010902)2.04394685
108Short hallux (HP:0010109)2.03968389
109Cupped ribs (HP:0000887)2.03739242
110Hyperglycinuria (HP:0003108)2.03597056
111Late onset (HP:0003584)2.03198142
112Abnormality of pyrimidine metabolism (HP:0004353)2.03005350
113Hypophosphatemia (HP:0002148)2.02797687
114Abnormality of nucleobase metabolism (HP:0010932)2.01098770
115Prolonged QT interval (HP:0001657)2.00436539
116Abnormality of purine metabolism (HP:0004352)2.00224921
117Ventricular arrhythmia (HP:0004308)2.00011783
118Abnormality of the gastric mucosa (HP:0004295)1.98680232
119Delayed epiphyseal ossification (HP:0002663)1.98624000
120Hypolipoproteinemia (HP:0010981)1.98428948
121Curly hair (HP:0002212)1.98261632
122Ureteral obstruction (HP:0006000)1.98120188
123Pancreatitis (HP:0001733)1.95733231
124Symptomatic seizures (HP:0011145)1.95447264
125Hyperphosphatemia (HP:0002905)1.94329784
126Adrenal overactivity (HP:0002717)1.92898789
127Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.92659867
128Abnormal atrioventricular conduction (HP:0005150)1.91319845
129Abnormality of the costochondral junction (HP:0000919)1.91311276
130Abnormal hair laboratory examination (HP:0003328)1.90521038
131Heart block (HP:0012722)1.89637775
132Posterior subcapsular cataract (HP:0007787)1.88803269
133Milia (HP:0001056)1.88409472
134Metabolic acidosis (HP:0001942)1.87955651
135Glomerulosclerosis (HP:0000096)1.86703443
136Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.83931702
137Visceral angiomatosis (HP:0100761)1.83909485
138Hypoglycemic coma (HP:0001325)1.83032978
139Gingivitis (HP:0000230)1.82839688
140Aplasia/Hypoplasia of the hallux (HP:0008362)1.82072351
141Broad metatarsal (HP:0001783)1.80563397
142Abnormality of serine family amino acid metabolism (HP:0010894)1.80362171
143Abnormality of glycine metabolism (HP:0010895)1.80362171
144Fragile nails (HP:0001808)1.79586099
145Bone pain (HP:0002653)1.79287135
146Alopecia of scalp (HP:0002293)1.78782582
147Neoplasm of the rectum (HP:0100743)1.78606470
148Fat malabsorption (HP:0002630)1.74923527
149Abnormality of sodium homeostasis (HP:0010931)1.74880917
150Vacuolated lymphocytes (HP:0001922)1.74724701
151Deviation of the thumb (HP:0009603)1.74542269
152Neck muscle weakness (HP:0000467)1.74148454
153Atrophic scars (HP:0001075)1.72158564

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B7.20083282
2MST1R6.00033875
3PIK3CA4.86681957
4LMTK24.79301247
5MST44.12082199
6MYLK4.00410016
7EPHA23.87676869
8FRK2.99592635
9KSR22.82749933
10MAP2K22.77773394
11MAP3K22.74955902
12TESK12.63729475
13DMPK2.53037984
14PRKG22.29500779
15EPHB22.28998229
16MET2.17007455
17RIPK11.88631191
18STK241.72794677
19MAP2K11.66820397
20NME11.65491380
21PTK61.59537253
22FGFR41.54924847
23EPHA31.49133267
24LIMK11.45106013
25TYK21.27611097
26MAP3K71.27405596
27GRK61.24570633
28WNK41.22575029
29MAP3K101.21681086
30TTN1.20980260
31DDR21.20215071
32NUAK11.15378798
33PKN21.12996673
34RIPK41.11383097
35PAK21.11139146
36CASK1.05995141
37TNIK1.05958294
38TRIB31.05050103
39MAP3K11.03620106
40PAK41.00678284
41STK100.99361566
42PIK3CG0.98774378
43FER0.97990273
44PRPF4B0.97353245
45MAP3K90.95501544
46FGFR30.95493380
47MATK0.94456757
48EPHB10.93953157
49EEF2K0.93608712
50TAOK10.90919588
51NLK0.89564960
52LRRK20.87894209
53PTK20.84680994
54ERBB20.82966270
55MAP3K80.80133477
56CAMK2D0.79610349
57BMPR20.73008238
58PAK30.72966034
59ERN10.72499849
60ROCK10.69730222
61PRKAA20.66188094
62ABL20.66169677
63MAP2K60.65823822
64PDPK10.61007636
65RAF10.59057222
66DAPK30.58244119
67PAK10.57591975
68MAPK110.56982978
69PRKCI0.56363331
70MAP4K10.56251265
71CDC42BPA0.53899792
72ROCK20.53775431
73CSK0.52127256
74BMX0.51483450
75PRKAA10.50053821
76PDK10.46641659
77IRAK10.46159217
78STK390.45835170
79CDK190.45699991
80CAMK2G0.45416883
81ILK0.45106081
82CAMKK10.44765852
83ICK0.43141230
84MAP3K120.41383477
85RET0.41230667
86JAK20.41151201
87ZAP700.40625371
88FYN0.40375796
89EPHA40.40283146
90JAK10.39066270
91SRC0.38612454
92CAMK2B0.35356909
93PIM10.35190489
94CSNK1A10.34841466
95WNK10.34642649
96GRK10.34511840
97ALK0.33969680
98PRKCD0.33710793
99PRKCZ0.33656654
100TBK10.32214584
101FGR0.31995362
102PDK40.31654425
103PDK30.31654425
104YES10.31629388
105PRKCA0.30852193
106RPS6KB20.30720676
107NEK10.29820269
108PRKACG0.29526591
109IKBKE0.29468416
110GSK3A0.29141439
111MAPKAPK30.29077807
112LYN0.27015664
113CDK60.26819844
114TESK20.25633129
115PDK20.25507256
116MAPKAPK20.25186845
117PDGFRA0.24558600
118PTK2B0.23916222
119KSR10.23316552
120AKT30.23100363
121STK38L0.22833274
122TAOK30.21692946
123DYRK1B0.21223282
124KDR0.20459744
125PRKG10.19740068
126MAP3K130.18491531
127OXSR10.17565022
128MAP3K110.17488292
129PRKCQ0.16823733
130IGF1R0.16807060
131CAMK2A0.16426250
132ARAF0.16373676
133SYK0.16080552
134MAP3K140.14840081
135PRKCB0.14518080
136KIT0.13212789
137RPS6KA20.12318702
138JAK30.11699070
139CSF1R0.10450902
140BLK0.10411446
141SGK10.10081139
142MELK0.09711159

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009206.66342238
2Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005124.00208669
3Mineral absorption_Homo sapiens_hsa049783.91989287
4Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005333.73139935
5Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.16248257
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.98094420
7Vitamin digestion and absorption_Homo sapiens_hsa049772.87686299
8Bile secretion_Homo sapiens_hsa049762.65081130
9Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.22575207
10Pancreatic secretion_Homo sapiens_hsa049722.19411661
11Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.12923128
12Drug metabolism - other enzymes_Homo sapiens_hsa009832.03217640
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.99548221
14Retinol metabolism_Homo sapiens_hsa008301.83264756
15Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.78017706
16Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.60986949
17Renin secretion_Homo sapiens_hsa049241.51149515
18Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.50130246
19Vibrio cholerae infection_Homo sapiens_hsa051101.48204859
20Fat digestion and absorption_Homo sapiens_hsa049751.45758594
21Butanoate metabolism_Homo sapiens_hsa006501.42376145
22Pentose and glucuronate interconversions_Homo sapiens_hsa000401.39944852
23Asthma_Homo sapiens_hsa053101.38846248
24Histidine metabolism_Homo sapiens_hsa003401.35863737
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.35647144
26Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.28725791
27Tight junction_Homo sapiens_hsa045301.27293712
28Fructose and mannose metabolism_Homo sapiens_hsa000511.23221489
29Fatty acid degradation_Homo sapiens_hsa000711.21692185
30Salivary secretion_Homo sapiens_hsa049701.14173059
31Maturity onset diabetes of the young_Homo sapiens_hsa049501.11105848
32Arachidonic acid metabolism_Homo sapiens_hsa005901.10764967
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.10742738
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09596537
35Tryptophan metabolism_Homo sapiens_hsa003801.08840349
36Nitrogen metabolism_Homo sapiens_hsa009101.01701231
37Thyroid cancer_Homo sapiens_hsa052160.97211670
38Galactose metabolism_Homo sapiens_hsa000520.95765226
39Gastric acid secretion_Homo sapiens_hsa049710.95557053
40Protein digestion and absorption_Homo sapiens_hsa049740.94730928
41Starch and sucrose metabolism_Homo sapiens_hsa005000.93202390
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90394791
43Ether lipid metabolism_Homo sapiens_hsa005650.87741830
44Thyroid hormone synthesis_Homo sapiens_hsa049180.87342455
45PPAR signaling pathway_Homo sapiens_hsa033200.86259055
46Vascular smooth muscle contraction_Homo sapiens_hsa042700.86119733
47Allograft rejection_Homo sapiens_hsa053300.85266247
48Adherens junction_Homo sapiens_hsa045200.81916422
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81508018
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.80705412
51Autoimmune thyroid disease_Homo sapiens_hsa053200.80231060
52Carbon metabolism_Homo sapiens_hsa012000.78326147
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.78308813
54Salmonella infection_Homo sapiens_hsa051320.76590514
55Graft-versus-host disease_Homo sapiens_hsa053320.76142951
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75984623
57Renin-angiotensin system_Homo sapiens_hsa046140.74928176
58Staphylococcus aureus infection_Homo sapiens_hsa051500.74190799
59Amoebiasis_Homo sapiens_hsa051460.73363196
60Pyruvate metabolism_Homo sapiens_hsa006200.72322950
61Glycerolipid metabolism_Homo sapiens_hsa005610.65996357
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.63425536
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61120927
64Propanoate metabolism_Homo sapiens_hsa006400.60584443
65alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.59452502
66Sulfur relay system_Homo sapiens_hsa041220.59111936
67Type I diabetes mellitus_Homo sapiens_hsa049400.58360845
68Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56231837
69Caffeine metabolism_Homo sapiens_hsa002320.55606026
70Insulin secretion_Homo sapiens_hsa049110.54362485
71Bladder cancer_Homo sapiens_hsa052190.52914608
72Sphingolipid metabolism_Homo sapiens_hsa006000.51606902
73Fatty acid metabolism_Homo sapiens_hsa012120.49765941
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48858664
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46751794
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.46743855
77Peroxisome_Homo sapiens_hsa041460.46537901
78Pentose phosphate pathway_Homo sapiens_hsa000300.44669229
79Cyanoamino acid metabolism_Homo sapiens_hsa004600.44471582
80Steroid hormone biosynthesis_Homo sapiens_hsa001400.43151362
81Other glycan degradation_Homo sapiens_hsa005110.42670129
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41853138
83Linoleic acid metabolism_Homo sapiens_hsa005910.41133884
84N-Glycan biosynthesis_Homo sapiens_hsa005100.40793937
85Folate biosynthesis_Homo sapiens_hsa007900.40644308
86Phenylalanine metabolism_Homo sapiens_hsa003600.39908234
87Tyrosine metabolism_Homo sapiens_hsa003500.38787275
88Antigen processing and presentation_Homo sapiens_hsa046120.38506235
89Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.37342016
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.37088950
91Dorso-ventral axis formation_Homo sapiens_hsa043200.35906283
92Leishmaniasis_Homo sapiens_hsa051400.35448933
93ABC transporters_Homo sapiens_hsa020100.34892031
94Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32330058
95Insulin resistance_Homo sapiens_hsa049310.31669101
96Cardiac muscle contraction_Homo sapiens_hsa042600.31401684
97Alzheimers disease_Homo sapiens_hsa050100.31344853
98Glutathione metabolism_Homo sapiens_hsa004800.30001341
99GnRH signaling pathway_Homo sapiens_hsa049120.29613073
100Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27572125
101Hepatitis C_Homo sapiens_hsa051600.27048516
102Fatty acid biosynthesis_Homo sapiens_hsa000610.26794600
103Cholinergic synapse_Homo sapiens_hsa047250.26774397
104Pertussis_Homo sapiens_hsa051330.26652921
105Cocaine addiction_Homo sapiens_hsa050300.26285548
106beta-Alanine metabolism_Homo sapiens_hsa004100.26266702
107Endometrial cancer_Homo sapiens_hsa052130.26232198
108Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.25796172
109Platelet activation_Homo sapiens_hsa046110.24985614
110Chemical carcinogenesis_Homo sapiens_hsa052040.24755180
111Type II diabetes mellitus_Homo sapiens_hsa049300.23032206
112Arginine and proline metabolism_Homo sapiens_hsa003300.23018468
113Regulation of actin cytoskeleton_Homo sapiens_hsa048100.22996060
114Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.22209966
115Estrogen signaling pathway_Homo sapiens_hsa049150.21938015
116Long-term depression_Homo sapiens_hsa047300.21432495
117Gap junction_Homo sapiens_hsa045400.21406661
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.20988167
119Glycerophospholipid metabolism_Homo sapiens_hsa005640.19623634
120Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.18487277
121Arginine biosynthesis_Homo sapiens_hsa002200.17316095
122Metabolic pathways_Homo sapiens_hsa011000.17154932
123Viral myocarditis_Homo sapiens_hsa054160.16893331
124Focal adhesion_Homo sapiens_hsa045100.16329114
125Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.16165166
126Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.14728967
127Primary bile acid biosynthesis_Homo sapiens_hsa001200.12261880
128Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.11951465
129Adipocytokine signaling pathway_Homo sapiens_hsa049200.11791235
130Toxoplasmosis_Homo sapiens_hsa051450.11405730
131African trypanosomiasis_Homo sapiens_hsa051430.08396514
132Chemokine signaling pathway_Homo sapiens_hsa040620.07582702
133Influenza A_Homo sapiens_hsa051640.05214810
134Tuberculosis_Homo sapiens_hsa051520.03663204
135Systemic lupus erythematosus_Homo sapiens_hsa053220.03112554
136Fatty acid elongation_Homo sapiens_hsa000620.01033689
137Biosynthesis of amino acids_Homo sapiens_hsa012300.00761711

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »