RFC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* DNA strand elongation involved in DNA replication (GO:0006271)5.75132513
2* telomere maintenance via semi-conservative replication (GO:0032201)5.69021804
3* DNA strand elongation (GO:0022616)5.47489164
4DNA deamination (GO:0045006)5.22582069
5ribosomal small subunit assembly (GO:0000028)5.17287202
6DNA replication initiation (GO:0006270)5.10962378
7* telomere maintenance via recombination (GO:0000722)5.02266609
8* mitotic recombination (GO:0006312)4.63424241
9DNA unwinding involved in DNA replication (GO:0006268)4.58787778
10DNA replication checkpoint (GO:0000076)4.36998155
11* telomere maintenance via telomere lengthening (GO:0010833)4.34864276
12viral transcription (GO:0019083)4.33050700
13maturation of SSU-rRNA (GO:0030490)4.25559463
14deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.23492762
15* nucleotide-excision repair, DNA gap filling (GO:0006297)4.20784093
16translational termination (GO:0006415)4.20275527
17ribosomal small subunit biogenesis (GO:0042274)4.16757489
18mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.97063972
19CENP-A containing nucleosome assembly (GO:0034080)3.95283767
20chromatin remodeling at centromere (GO:0031055)3.88502006
21translational elongation (GO:0006414)3.82073178
22nucleobase biosynthetic process (GO:0046112)3.81577466
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.78967055
24regulation of mitochondrial translation (GO:0070129)3.77264121
25mitotic sister chromatid segregation (GO:0000070)3.73978760
26cotranslational protein targeting to membrane (GO:0006613)3.71664095
27ribosomal large subunit biogenesis (GO:0042273)3.69838782
28protein targeting to ER (GO:0045047)3.67849769
29establishment of viral latency (GO:0019043)3.67656150
30DNA replication-dependent nucleosome assembly (GO:0006335)3.66758287
31DNA replication-dependent nucleosome organization (GO:0034723)3.66758287
32DNA replication-independent nucleosome organization (GO:0034724)3.60925134
33DNA replication-independent nucleosome assembly (GO:0006336)3.60925134
34purine nucleobase biosynthetic process (GO:0009113)3.56325203
35ATP synthesis coupled proton transport (GO:0015986)3.55696047
36energy coupled proton transport, down electrochemical gradient (GO:0015985)3.55696047
37establishment of protein localization to mitochondrial membrane (GO:0090151)3.54071563
38establishment of protein localization to endoplasmic reticulum (GO:0072599)3.48488079
39translational initiation (GO:0006413)3.47643503
40protein localization to endoplasmic reticulum (GO:0070972)3.47420745
41chaperone-mediated protein transport (GO:0072321)3.46159562
42establishment of integrated proviral latency (GO:0075713)3.45058732
43proteasome assembly (GO:0043248)3.43180001
44nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.42985915
45intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.42206699
46signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.42206699
47* transcription-coupled nucleotide-excision repair (GO:0006283)3.41342241
48signal transduction involved in DNA integrity checkpoint (GO:0072401)3.41085054
49signal transduction involved in DNA damage checkpoint (GO:0072422)3.41085054
50ribonucleoprotein complex biogenesis (GO:0022613)3.40386178
51regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.38737199
52folic acid-containing compound biosynthetic process (GO:0009396)3.38307712
53regulation of cellular amino acid metabolic process (GO:0006521)3.37664879
54signal transduction involved in cell cycle checkpoint (GO:0072395)3.35067749
55ribosome assembly (GO:0042255)3.34959113
56spliceosomal snRNP assembly (GO:0000387)3.34327933
57cellular protein complex disassembly (GO:0043624)3.33753077
58mitotic chromosome condensation (GO:0007076)3.33441937
59sister chromatid segregation (GO:0000819)3.31618179
60viral life cycle (GO:0019058)3.31603182
61* telomere organization (GO:0032200)3.30385442
62* telomere maintenance (GO:0000723)3.29017353
63formation of translation preinitiation complex (GO:0001731)3.28027823
64positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.27890500
65pseudouridine synthesis (GO:0001522)3.27160608
66kinetochore organization (GO:0051383)3.26588255
67IMP biosynthetic process (GO:0006188)3.25455454
68protein localization to kinetochore (GO:0034501)3.22389271
69DNA ligation (GO:0006266)3.21626396
70mismatch repair (GO:0006298)3.21220234
71deoxyribonucleotide biosynthetic process (GO:0009263)3.20712690
72histone exchange (GO:0043486)3.20688085
73pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.20524697
74DNA catabolic process, exonucleolytic (GO:0000738)3.20409447
75rRNA processing (GO:0006364)3.20157558
76negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.16489828
77L-serine metabolic process (GO:0006563)3.15637081
78exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.15311404
79somatic hypermutation of immunoglobulin genes (GO:0016446)3.15123506
80somatic diversification of immune receptors via somatic mutation (GO:0002566)3.15123506
81positive regulation of ligase activity (GO:0051351)3.14113031
82regulation of double-strand break repair via homologous recombination (GO:0010569)3.13225891
83regulation of nuclear cell cycle DNA replication (GO:0033262)3.12950646
84translesion synthesis (GO:0019985)3.11094279
85regulation of ubiquitin-protein transferase activity (GO:0051438)3.09512449
86rRNA metabolic process (GO:0016072)3.09195706
87replication fork processing (GO:0031297)3.09016756
88maturation of 5.8S rRNA (GO:0000460)3.08861667
89viral mRNA export from host cell nucleus (GO:0046784)3.06048820
90protein K6-linked ubiquitination (GO:0085020)3.05837204
91nucleobase-containing small molecule interconversion (GO:0015949)3.05560351
92translation (GO:0006412)3.04972819
93kinetochore assembly (GO:0051382)3.04922288
94protein complex disassembly (GO:0043241)3.04707876
95nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.04069988
96ribosome biogenesis (GO:0042254)3.03822911
97protein targeting to mitochondrion (GO:0006626)3.03622608
98protein localization to chromosome, centromeric region (GO:0071459)3.02401240
99mitotic nuclear envelope disassembly (GO:0007077)3.01423479
100regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.01354148
101cell cycle G1/S phase transition (GO:0044843)2.99160898
102G1/S transition of mitotic cell cycle (GO:0000082)2.99160898
103anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.98900390
104regulation of ligase activity (GO:0051340)2.98653950
105cullin deneddylation (GO:0010388)2.98464079
106IMP metabolic process (GO:0046040)2.96706173
107spliceosomal complex assembly (GO:0000245)2.96555799
108transcription elongation from RNA polymerase III promoter (GO:0006385)2.96522301
109termination of RNA polymerase III transcription (GO:0006386)2.96522301
110negative regulation of ligase activity (GO:0051352)2.95894616
111negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.95894616
112mitotic metaphase plate congression (GO:0007080)2.95469440
113intra-S DNA damage checkpoint (GO:0031573)2.94434576
114maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.93086918
115pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.92416455
116positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.90740271
117macromolecular complex disassembly (GO:0032984)2.90312827
118histone H2A acetylation (GO:0043968)2.89526660
119nuclear-transcribed mRNA catabolic process (GO:0000956)2.88454623
120deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.88192938
121base-excision repair (GO:0006284)2.87947201
122DNA-dependent DNA replication (GO:0006261)2.86092281
123* DNA replication (GO:0006260)2.83896185
124pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.82750700
125postreplication repair (GO:0006301)2.81997362
126attachment of spindle microtubules to kinetochore (GO:0008608)2.79553361
1277-methylguanosine mRNA capping (GO:0006370)2.78223039
128pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.77869075
129rRNA modification (GO:0000154)2.77568192
130DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.76966367
131signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.76060037
132signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.76060037
133signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.76060037

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.14235453
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.03745846
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.64621893
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.59846875
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.56678337
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.17388590
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.08281099
8* GABP_17652178_ChIP-ChIP_JURKAT_Human3.07956555
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.97967513
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.92836752
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.89153873
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.88801176
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88587326
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.80756338
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.74913103
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69428519
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.68504488
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.65898324
19* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.50963390
20* VDR_23849224_ChIP-Seq_CD4+_Human2.40796545
21XRN2_22483619_ChIP-Seq_HELA_Human2.32918281
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.31562024
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.28985775
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.26491671
25FOXP3_21729870_ChIP-Seq_TREG_Human2.19443577
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16393912
27* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.16255589
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13152376
29DCP1A_22483619_ChIP-Seq_HELA_Human1.97561098
30* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.95790272
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.94339118
32THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92858078
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.90938385
34TTF2_22483619_ChIP-Seq_HELA_Human1.89948648
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.88416727
36* GABP_19822575_ChIP-Seq_HepG2_Human1.85855458
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.84724832
38CIITA_25753668_ChIP-Seq_RAJI_Human1.81820073
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81635273
40SRF_21415370_ChIP-Seq_HL-1_Mouse1.76494775
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.75927788
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.74096514
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.73212618
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65627118
45ELK1_19687146_ChIP-ChIP_HELA_Human1.65393178
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.63490007
47AR_21909140_ChIP-Seq_LNCAP_Human1.63422701
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63050243
49* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.60887672
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.59019653
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.58976686
52* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.55960891
53POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.48233909
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47794103
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.41449479
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.37665668
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.35549721
58PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32068196
59SPI1_23547873_ChIP-Seq_NB4_Human1.28265496
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.27023166
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.25602949
62MYC_22102868_ChIP-Seq_BL_Human1.25310693
63KDM5A_27292631_Chip-Seq_BREAST_Human1.25184654
64VDR_21846776_ChIP-Seq_THP-1_Human1.21833845
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.21314068
66E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19118332
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18798256
68GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.18106464
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.14650380
70TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.13854317
71MYC_18940864_ChIP-ChIP_HL60_Human1.12807432
72ESR1_15608294_ChIP-ChIP_MCF-7_Human1.05728076
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05331290
74TP63_19390658_ChIP-ChIP_HaCaT_Human1.05244729
75CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.05122440
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.04347612
77KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.03065491
78SCL_19346495_ChIP-Seq_HPC-7_Human1.02696649
79CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01688879
80POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.98647015
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96648483
82* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.96558463
83* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95929799
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.95796159
85MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.94249810
86TFEB_21752829_ChIP-Seq_HELA_Human0.91944090
87SOX2_18555785_ChIP-Seq_MESCs_Mouse0.91385529
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90869478
89EGR1_19374776_ChIP-ChIP_THP-1_Human0.89276244
90CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89027277
91DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.86416853
92HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.85886762
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85381619
94KLF4_18555785_ChIP-Seq_MESCs_Mouse0.84871518
95STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84549918
96FOXP1_21924763_ChIP-Seq_HESCs_Human0.84246418
97ELK1_22589737_ChIP-Seq_MCF10A_Human0.82716549
98CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82107741
99* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.81950327
100RBPJ_22232070_ChIP-Seq_NCS_Mouse0.81673325
101* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81535976
102* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80687747
103STAT4_19710469_ChIP-ChIP_TH1__Mouse0.79911402
104ZNF263_19887448_ChIP-Seq_K562_Human0.78820868
105TBX5_21415370_ChIP-Seq_HL-1_Mouse0.78633750
106NANOG_16153702_ChIP-ChIP_HESCs_Human0.77971923
107IRF1_19129219_ChIP-ChIP_H3396_Human0.77767449
108* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.77360511
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.76654008
110ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.76232759
111SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.76061399
112CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.75978905
113* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75483215
114SOX17_20123909_ChIP-Seq_XEN_Mouse0.75069155
115IRF8_22096565_ChIP-ChIP_GC-B_Human0.73420832
116* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.72207266

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.91649609
2MP0010094_abnormal_chromosome_stability4.80869624
3MP0008057_abnormal_DNA_replication4.15484356
4MP0003111_abnormal_nucleus_morphology4.11194825
5MP0008058_abnormal_DNA_repair3.73918329
6MP0003077_abnormal_cell_cycle3.67559821
7MP0004957_abnormal_blastocyst_morpholog3.67272588
8MP0002396_abnormal_hematopoietic_system3.11402564
9MP0008007_abnormal_cellular_replicative3.00638313
10MP0008932_abnormal_embryonic_tissue2.50211457
11MP0008877_abnormal_DNA_methylation2.18790091
12MP0000490_abnormal_crypts_of2.06024308
13MP0003786_premature_aging2.02328549
14MP0005174_abnormal_tail_pigmentation1.90588036
15MP0006035_abnormal_mitochondrial_morpho1.90443477
16MP0005075_abnormal_melanosome_morpholog1.88121731
17MP0003763_abnormal_thymus_physiology1.86250269
18MP0001835_abnormal_antigen_presentation1.79118395
19MP0009697_abnormal_copulation1.77450014
20MP0000350_abnormal_cell_proliferation1.71133794
21MP0009379_abnormal_foot_pigmentation1.70959409
22MP0004808_abnormal_hematopoietic_stem1.70141944
23MP0010030_abnormal_orbit_morphology1.68814147
24MP0002398_abnormal_bone_marrow1.65066948
25MP0009333_abnormal_splenocyte_physiolog1.64743998
26MP0006292_abnormal_olfactory_placode1.60255894
27MP0000313_abnormal_cell_death1.60037021
28MP0001730_embryonic_growth_arrest1.55077052
29MP0001545_abnormal_hematopoietic_system1.53364834
30MP0005397_hematopoietic_system_phenotyp1.53364834
31MP0002019_abnormal_tumor_incidence1.50651620
32MP0002095_abnormal_skin_pigmentation1.50163452
33MP0000015_abnormal_ear_pigmentation1.47901709
34MP0000689_abnormal_spleen_morphology1.43254577
35MP0002210_abnormal_sex_determination1.40892495
36MP0002722_abnormal_immune_system1.39414393
37MP0000703_abnormal_thymus_morphology1.37579550
38MP0002132_abnormal_respiratory_system1.36181501
39MP0001986_abnormal_taste_sensitivity1.34022589
40MP0005671_abnormal_response_to1.33651098
41MP0002429_abnormal_blood_cell1.32497087
42MP0001800_abnormal_humoral_immune1.29404978
43MP0001929_abnormal_gametogenesis1.28589985
44MP0000716_abnormal_immune_system1.26839689
45MP0002160_abnormal_reproductive_system1.26679928
46MP0002420_abnormal_adaptive_immunity1.25659105
47MP0001819_abnormal_immune_cell1.22762949
48MP0002102_abnormal_ear_morphology1.21531253
49MP0001145_abnormal_male_reproductive1.21193980
50MP0002452_abnormal_antigen_presenting1.18673894
51MP0010307_abnormal_tumor_latency1.13462365
52MP0003941_abnormal_skin_development1.13334213
53MP0009785_altered_susceptibility_to1.13173921
54MP0002080_prenatal_lethality1.12816592
55MP0000465_gastrointestinal_hemorrhage1.12593587
56MP0003315_abnormal_perineum_morphology1.12350026
57MP0005410_abnormal_fertilization1.12151756
58MP0001293_anophthalmia1.11506360
59MP0001697_abnormal_embryo_size1.11410665
60MP0002723_abnormal_immune_serum1.09793080
61MP0005025_abnormal_response_to1.08234483
62MP0004147_increased_porphyrin_level1.07198221
63MP0002148_abnormal_hypersensitivity_rea1.06890818
64MP0001853_heart_inflammation1.06868354
65MP0003186_abnormal_redox_activity1.05725758
66MP0009672_abnormal_birth_weight1.03607204
67MP0003123_paternal_imprinting1.02966447
68MP0001727_abnormal_embryo_implantation1.02225898
69MP0006054_spinal_hemorrhage1.01940362
70MP0000653_abnormal_sex_gland1.01262437
71MP0001346_abnormal_lacrimal_gland1.00448962
72MP0000685_abnormal_immune_system0.99347985
73MP0005000_abnormal_immune_tolerance0.99334002
74MP0003718_maternal_effect0.97376118
75MP0001672_abnormal_embryogenesis/_devel0.96781442
76MP0005380_embryogenesis_phenotype0.96781442
77MP0003806_abnormal_nucleotide_metabolis0.96561750
78MP0001529_abnormal_vocalization0.94652069
79MP0000858_altered_metastatic_potential0.94066142
80MP0001188_hyperpigmentation0.92205813
81MP0002085_abnormal_embryonic_tissue0.90208127
82MP0002938_white_spotting0.89955736
83MP0005409_darkened_coat_color0.89530197
84MP0002405_respiratory_system_inflammati0.89404439
85MP0000372_irregular_coat_pigmentation0.89199016
86MP0003937_abnormal_limbs/digits/tail_de0.87136639
87MP0005389_reproductive_system_phenotype0.86706308
88MP0006036_abnormal_mitochondrial_physio0.86642130
89MP0003567_abnormal_fetal_cardiomyocyte0.86233516
90MP0003698_abnormal_male_reproductive0.86050949
91MP0005464_abnormal_platelet_physiology0.85545455
92MP0001919_abnormal_reproductive_system0.84967368
93MP0002111_abnormal_tail_morphology0.84951302
94MP0004133_heterotaxia0.84299611
95MP0004233_abnormal_muscle_weight0.84243236
96MP0001881_abnormal_mammary_gland0.83974106
97MP0002163_abnormal_gland_morphology0.83199842
98MP0003984_embryonic_growth_retardation0.82687369
99MP0002877_abnormal_melanocyte_morpholog0.82342798
100MP0000358_abnormal_cell_content/0.81374502
101MP0002697_abnormal_eye_size0.81334441
102MP0000049_abnormal_middle_ear0.80056398
103MP0003121_genomic_imprinting0.79404105
104MP0004197_abnormal_fetal_growth/weight/0.78883980
105MP0002419_abnormal_innate_immunity0.78809532
106MP0005408_hypopigmentation0.78289127
107MP0003136_yellow_coat_color0.78037063
108MP0001119_abnormal_female_reproductive0.77953374
109MP0002088_abnormal_embryonic_growth/wei0.77384335
110MP0005501_abnormal_skin_physiology0.76487843
111MP0003890_abnormal_embryonic-extraembry0.76312278
112MP0001764_abnormal_homeostasis0.74588108
113MP0002086_abnormal_extraembryonic_tissu0.74183695
114MP0002075_abnormal_coat/hair_pigmentati0.73985302
115MP0000566_synostosis0.73854376
116MP0003866_abnormal_defecation0.72997203
117MP0008260_abnormal_autophagy0.71001893
118MP0004381_abnormal_hair_follicle0.70805343
119MP0002751_abnormal_autonomic_nervous0.70484764
120MP0008789_abnormal_olfactory_epithelium0.69323592
121MP0006072_abnormal_retinal_apoptosis0.69309977
122MP0008995_early_reproductive_senescence0.68890019
123MP0005384_cellular_phenotype0.68697573
124MP0002084_abnormal_developmental_patter0.67396998
125MP0010352_gastrointestinal_tract_polyps0.65830330
126MP0001661_extended_life_span0.63545493
127MP0001286_abnormal_eye_development0.62802820
128MP0009278_abnormal_bone_marrow0.61265416
129MP0000647_abnormal_sebaceous_gland0.60516256
130MP0002736_abnormal_nociception_after0.58994893
131MP0005266_abnormal_metabolism0.58368049
132MP0002161_abnormal_fertility/fecundity0.56908298
133MP0005379_endocrine/exocrine_gland_phen0.55772527
134MP0003119_abnormal_digestive_system0.55656481
135MP0000537_abnormal_urethra_morphology0.55263053
136MP0008872_abnormal_physiological_respon0.54179130
137MP0000678_abnormal_parathyroid_gland0.53376293
138MP0003646_muscle_fatigue0.52619867
139MP0008873_increased_physiological_sensi0.52562105

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.18011934
2Abnormality of cells of the erythroid lineage (HP:0012130)4.67486747
3Abnormal number of erythroid precursors (HP:0012131)4.63684730
4Birth length less than 3rd percentile (HP:0003561)4.33928260
5Chromsome breakage (HP:0040012)4.08405635
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.98725349
7Aplastic anemia (HP:0001915)3.96537071
8Acute encephalopathy (HP:0006846)3.84502106
9Oral leukoplakia (HP:0002745)3.46437699
10Abnormality of the preputium (HP:0100587)3.30140504
11Pallor (HP:0000980)3.25096909
12Increased serum pyruvate (HP:0003542)3.22602007
13Macrocytic anemia (HP:0001972)3.22402920
14Abnormality of glycolysis (HP:0004366)3.20673856
15Progressive macrocephaly (HP:0004481)3.15905072
16Abnormality of chromosome stability (HP:0003220)3.14217749
17Breast hypoplasia (HP:0003187)3.12320140
18Meckel diverticulum (HP:0002245)3.11903706
19IgM deficiency (HP:0002850)3.09943559
20Abnormality of the ileum (HP:0001549)3.00131081
21Cerebral edema (HP:0002181)2.97164648
22Aplasia/Hypoplasia of the sacrum (HP:0008517)2.88963740
23Aplasia/Hypoplasia of the uvula (HP:0010293)2.85377179
24Bone marrow hypocellularity (HP:0005528)2.84603194
25Lactic acidosis (HP:0003128)2.83520094
26Duplicated collecting system (HP:0000081)2.83023549
27Pancytopenia (HP:0001876)2.79267240
2811 pairs of ribs (HP:0000878)2.76914672
29Type I transferrin isoform profile (HP:0003642)2.75056168
30Thrombocytosis (HP:0001894)2.74243582
31Abnormality of the renal collecting system (HP:0004742)2.70064421
32Myelodysplasia (HP:0002863)2.68041390
33Patellar aplasia (HP:0006443)2.66178008
34Colon cancer (HP:0003003)2.64102083
35Agnosia (HP:0010524)2.62422928
36Absent thumb (HP:0009777)2.60161968
37Increased intramyocellular lipid droplets (HP:0012240)2.55972506
38Cerebral hypomyelination (HP:0006808)2.52913322
39Premature graying of hair (HP:0002216)2.52878018
40Small intestinal stenosis (HP:0012848)2.51226694
41Duodenal stenosis (HP:0100867)2.51226694
42Aplasia/Hypoplasia of the patella (HP:0006498)2.51079295
43Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.49823989
44Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.49410279
45Rough bone trabeculation (HP:0100670)2.47736569
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.45399472
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.45399472
48Petechiae (HP:0000967)2.43370671
49Abnormality of DNA repair (HP:0003254)2.40622133
50Lymphoma (HP:0002665)2.34437097
51* Abnormality of the carotid arteries (HP:0005344)2.34040156
52Multiple enchondromatosis (HP:0005701)2.34015813
53Selective tooth agenesis (HP:0001592)2.33804470
54Exercise intolerance (HP:0003546)2.33329069
55Medulloblastoma (HP:0002885)2.33325559
56Microretrognathia (HP:0000308)2.31920029
57Abnormality of the labia minora (HP:0012880)2.31219270
58Type 2 muscle fiber atrophy (HP:0003554)2.30320214
59Respiratory failure (HP:0002878)2.29337439
60Abnormality of the anterior horn cell (HP:0006802)2.27671117
61Degeneration of anterior horn cells (HP:0002398)2.27671117
62Triphalangeal thumb (HP:0001199)2.27091622
63Muscle fiber atrophy (HP:0100295)2.26677637
64Hepatocellular necrosis (HP:0001404)2.26270441
65Increased serum lactate (HP:0002151)2.26130679
66Abnormality of the heme biosynthetic pathway (HP:0010472)2.25602922
67Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.23247663
68Abnormality of alanine metabolism (HP:0010916)2.23247663
69Hyperalaninemia (HP:0003348)2.23247663
70Clubbing of toes (HP:0100760)2.22709876
713-Methylglutaconic aciduria (HP:0003535)2.22533906
72Asplenia (HP:0001746)2.22266617
73Sloping forehead (HP:0000340)2.22038729
74Increased hepatocellular lipid droplets (HP:0006565)2.21967246
75Carpal bone hypoplasia (HP:0001498)2.21846600
76Abnormal number of incisors (HP:0011064)2.21223627
77Progressive muscle weakness (HP:0003323)2.20547129
78Exertional dyspnea (HP:0002875)2.17984885
79Mitochondrial inheritance (HP:0001427)2.16617644
80Neoplasm of the pancreas (HP:0002894)2.16421201
81Acute lymphatic leukemia (HP:0006721)2.15514677
82Leukodystrophy (HP:0002415)2.13327624
83Absent forearm bone (HP:0003953)2.13121433
84Aplasia involving forearm bones (HP:0009822)2.13121433
85Cellular immunodeficiency (HP:0005374)2.10342581
86Testicular atrophy (HP:0000029)2.08709807
87Reduced antithrombin III activity (HP:0001976)2.08540647
88Abnormal spermatogenesis (HP:0008669)2.08093482
89Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.07642399
90Abnormal protein N-linked glycosylation (HP:0012347)2.07642399
91Abnormal protein glycosylation (HP:0012346)2.07642399
92Abnormal glycosylation (HP:0012345)2.07642399
93Increased muscle lipid content (HP:0009058)2.06709994
94Horseshoe kidney (HP:0000085)2.05142676
95Abnormal lung lobation (HP:0002101)2.04663656
96Increased CSF lactate (HP:0002490)2.04278648
97Ectopic kidney (HP:0000086)2.04018311
98Chronic otitis media (HP:0000389)2.03183027
99Pancreatic cysts (HP:0001737)2.02703557
100Aplasia/Hypoplasia of the spleen (HP:0010451)2.02124270
101Squamous cell carcinoma (HP:0002860)1.99670025
102Facial cleft (HP:0002006)1.98375778
103Hypoplasia of the capital femoral epiphysis (HP:0003090)1.98262955
104Abnormality of the duodenum (HP:0002246)1.98212505
105Pulmonary fibrosis (HP:0002206)1.97810417
106True hermaphroditism (HP:0010459)1.97117032
107Recurrent bronchitis (HP:0002837)1.96946433
108Pancreatic fibrosis (HP:0100732)1.95489461
109Ependymoma (HP:0002888)1.94069458
110Hepatic necrosis (HP:0002605)1.92726015
111Acute necrotizing encephalopathy (HP:0006965)1.92441952
112Short thumb (HP:0009778)1.91696267
113Hypoplasia of the pons (HP:0012110)1.91683738
114IgG deficiency (HP:0004315)1.90831901
115Optic nerve coloboma (HP:0000588)1.90114618
116Microvesicular hepatic steatosis (HP:0001414)1.89255493
117Cleft eyelid (HP:0000625)1.89016809
118Abnormality of cochlea (HP:0000375)1.88882666
119Abnormality of T cell physiology (HP:0011840)1.88059805
120Respiratory difficulties (HP:0002880)1.87314892
121Absent radius (HP:0003974)1.86475042
122Lethargy (HP:0001254)1.86440694
123Sparse eyelashes (HP:0000653)1.85809938
124* Tracheoesophageal fistula (HP:0002575)1.84876910
125Progressive microcephaly (HP:0000253)1.82743536
126Lipid accumulation in hepatocytes (HP:0006561)1.81896212
127Amaurosis fugax (HP:0100576)1.81714747
128Abnormality of serum amino acid levels (HP:0003112)1.81655617
129Abnormal mitochondria in muscle tissue (HP:0008316)1.80863252
130Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.80450957
131Absent epiphyses (HP:0010577)1.80450957
132Optic disc pallor (HP:0000543)1.79079632
133Renal Fanconi syndrome (HP:0001994)1.77776670
134Elevated erythrocyte sedimentation rate (HP:0003565)1.77456766

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.38622656
2VRK24.34077904
3WEE13.95219978
4STK163.77441113
5CDC73.69021038
6EIF2AK12.87671881
7TLK12.62050529
8VRK12.56299590
9SRPK12.53732629
10ACVR1B2.49337746
11NME22.29027079
12PLK42.24218387
13EIF2AK32.20830633
14TESK22.02576059
15MKNK11.92207748
16NEK21.91125453
17TSSK61.88338364
18CCNB11.76087364
19MAP4K11.71072360
20ATR1.70750313
21PASK1.68780522
22IRAK41.68691507
23BRSK21.67261280
24DYRK31.66854422
25TTK1.64282754
26PLK11.53668168
27TAF11.48025957
28CDK71.46849377
29NUAK11.46536437
30SMG11.42985456
31MKNK21.35304255
32ZAK1.35120804
33AURKB1.33445511
34CLK11.30398388
35KIT1.29300308
36RPS6KB21.27570287
37BTK1.25457427
38TEC1.20048120
39IRAK31.19929976
40KDR1.17736872
41BRSK11.15038048
42BLK1.13954384
43RPS6KA41.13950965
44CHEK21.11558600
45TRIM281.07211360
46TGFBR11.06133182
47TESK11.04499065
48PIM21.02469863
49AURKA1.01901050
50CDK80.99757971
51EIF2AK20.95785521
52PDK20.94700090
53FLT30.93371898
54STK40.93311765
55PLK30.92856792
56EEF2K0.90533927
57PAK40.83602684
58CDK40.82836233
59CHEK10.82794989
60SCYL20.82362232
61CSF1R0.79368468
62MAPKAPK30.76103093
63CDK190.74208259
64NEK10.73992393
65MAP3K80.71688432
66TXK0.71528333
67YES10.68704241
68TNIK0.68657328
69CSNK2A10.68354842
70PIM10.67890185
71PBK0.65943205
72LYN0.65222482
73ATM0.64871351
74RPS6KA50.64141388
75CSNK2A20.63476061
76ABL20.63008864
77LIMK10.62984537
78SYK0.61918424
79CSNK1G10.61364813
80CSNK1A1L0.57809605
81BRD40.57455340
82MAP4K20.55166330
83CDK20.54408867
84STK100.54292192
85BMPR1B0.53530970
86MAP2K70.53373655
87ZAP700.53240249
88PAK10.52065484
89ALK0.50811944
90MAPKAPK50.48887962
91CSNK1G20.48179500
92IRAK10.46499999
93NME10.46306482
94ERBB40.46082711
95BCKDK0.45040555
96SIK30.44612786
97DYRK20.44191027
98TYK20.43393719
99CDK10.40411290
100MAP3K100.38415330
101CDK140.38346545
102IKBKB0.37750281
103CDK180.36621014
104CDK11A0.36569157
105DAPK10.36197481
106CDK150.35653000
107LCK0.35508398
108BRAF0.35196834
109PRKCI0.35185716
110MST40.34343086
111JAK30.33987627
112PRKDC0.33666467
113IRAK20.33309484
114NEK90.33277961
115MST1R0.33270950
116LRRK20.31441942
117CSNK1G30.31334473
118AKT20.30941153
119ARAF0.30311125
120GRK60.30274548
121WNK30.30005440
122EPHA20.29733690
123ADRBK20.29012279
124MAP2K30.28936261
125PLK20.27936366
126CSNK1E0.25094634
127TAOK20.24560290
128ILK0.23398981
129CDK90.22816087

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030305.69107449
2* Mismatch repair_Homo sapiens_hsa034304.45095554
3Ribosome_Homo sapiens_hsa030104.00711484
4Homologous recombination_Homo sapiens_hsa034403.53994346
5Base excision repair_Homo sapiens_hsa034103.43400908
6Proteasome_Homo sapiens_hsa030503.29594947
7Spliceosome_Homo sapiens_hsa030403.11676696
8RNA polymerase_Homo sapiens_hsa030203.08852509
9* Nucleotide excision repair_Homo sapiens_hsa034202.95850129
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.74676779
11Pyrimidine metabolism_Homo sapiens_hsa002402.73700637
12Fanconi anemia pathway_Homo sapiens_hsa034602.66017882
13Non-homologous end-joining_Homo sapiens_hsa034502.31667502
14Cell cycle_Homo sapiens_hsa041102.29234546
15RNA transport_Homo sapiens_hsa030132.27257761
16One carbon pool by folate_Homo sapiens_hsa006702.26057799
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.87358175
18Basal transcription factors_Homo sapiens_hsa030221.81408280
19RNA degradation_Homo sapiens_hsa030181.69559345
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.57889532
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.54581535
22Purine metabolism_Homo sapiens_hsa002301.53746057
23Protein export_Homo sapiens_hsa030601.50218470
24Fatty acid elongation_Homo sapiens_hsa000621.40225462
25Pyruvate metabolism_Homo sapiens_hsa006201.39399228
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.32681475
272-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.32360480
28mRNA surveillance pathway_Homo sapiens_hsa030151.27193531
29p53 signaling pathway_Homo sapiens_hsa041151.23743851
30Primary immunodeficiency_Homo sapiens_hsa053401.21406486
31Systemic lupus erythematosus_Homo sapiens_hsa053221.13490253
32Parkinsons disease_Homo sapiens_hsa050121.10482427
33Epstein-Barr virus infection_Homo sapiens_hsa051691.03890777
34Huntingtons disease_Homo sapiens_hsa050161.03553386
35Oxidative phosphorylation_Homo sapiens_hsa001900.97814410
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.97192411
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.96970579
38Antigen processing and presentation_Homo sapiens_hsa046120.96297217
39Herpes simplex infection_Homo sapiens_hsa051680.95041810
40Propanoate metabolism_Homo sapiens_hsa006400.87403409
41Folate biosynthesis_Homo sapiens_hsa007900.81478884
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.80904751
43Pentose phosphate pathway_Homo sapiens_hsa000300.79731044
44Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.78308177
45Sulfur relay system_Homo sapiens_hsa041220.73649763
46Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.72531347
47Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71528479
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71188520
49Viral carcinogenesis_Homo sapiens_hsa052030.70330051
50Steroid biosynthesis_Homo sapiens_hsa001000.67541944
51Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66121617
52N-Glycan biosynthesis_Homo sapiens_hsa005100.65967576
53Drug metabolism - other enzymes_Homo sapiens_hsa009830.62015769
54Hematopoietic cell lineage_Homo sapiens_hsa046400.59981798
55Other glycan degradation_Homo sapiens_hsa005110.57797581
56Glutathione metabolism_Homo sapiens_hsa004800.57642671
57HTLV-I infection_Homo sapiens_hsa051660.55811491
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.53074032
59Cysteine and methionine metabolism_Homo sapiens_hsa002700.53052232
60Legionellosis_Homo sapiens_hsa051340.52834799
61Measles_Homo sapiens_hsa051620.52818592
62Alzheimers disease_Homo sapiens_hsa050100.50821165
63Oocyte meiosis_Homo sapiens_hsa041140.50274001
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.49811681
65Asthma_Homo sapiens_hsa053100.49732304
66NF-kappa B signaling pathway_Homo sapiens_hsa040640.49638786
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48813802
68Cardiac muscle contraction_Homo sapiens_hsa042600.47888857
69Alcoholism_Homo sapiens_hsa050340.46776511
70Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.45986533
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.45610014
72Sulfur metabolism_Homo sapiens_hsa009200.44951078
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.43221525
74Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43160023
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.42929223
76Shigellosis_Homo sapiens_hsa051310.40923762
77Apoptosis_Homo sapiens_hsa042100.39796327
78Fatty acid metabolism_Homo sapiens_hsa012120.38718241
79Arachidonic acid metabolism_Homo sapiens_hsa005900.38232094
80Selenocompound metabolism_Homo sapiens_hsa004500.37010527
81RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.35923774
82Metabolic pathways_Homo sapiens_hsa011000.35315465
83Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35312908
84SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34322450
85Biosynthesis of amino acids_Homo sapiens_hsa012300.31786122
86Allograft rejection_Homo sapiens_hsa053300.31668861
87Renin-angiotensin system_Homo sapiens_hsa046140.29042994
88Peroxisome_Homo sapiens_hsa041460.28288852
89Hepatitis B_Homo sapiens_hsa051610.28286344
90B cell receptor signaling pathway_Homo sapiens_hsa046620.27925087
91Arginine and proline metabolism_Homo sapiens_hsa003300.27815218
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.26227921
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.25703950
94Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24465589
95Thyroid cancer_Homo sapiens_hsa052160.24218870
96Butanoate metabolism_Homo sapiens_hsa006500.22992969
97Influenza A_Homo sapiens_hsa051640.21906279
98Leishmaniasis_Homo sapiens_hsa051400.21463899
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.21236181
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.20477946
101Small cell lung cancer_Homo sapiens_hsa052220.19838717
102Tryptophan metabolism_Homo sapiens_hsa003800.19485557
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.19120925
104NOD-like receptor signaling pathway_Homo sapiens_hsa046210.18863000
105Graft-versus-host disease_Homo sapiens_hsa053320.18220053
106Notch signaling pathway_Homo sapiens_hsa043300.18213992
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.16110992
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.16099940
109Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.15561463
110Lysine degradation_Homo sapiens_hsa003100.15498054
111Vitamin B6 metabolism_Homo sapiens_hsa007500.15384790
112Autoimmune thyroid disease_Homo sapiens_hsa053200.14586618
113Galactose metabolism_Homo sapiens_hsa000520.13430366
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13302755
115Fatty acid degradation_Homo sapiens_hsa000710.12070302
116Jak-STAT signaling pathway_Homo sapiens_hsa046300.11814582
117Tyrosine metabolism_Homo sapiens_hsa003500.11590330
118Fructose and mannose metabolism_Homo sapiens_hsa000510.10533700
119Carbon metabolism_Homo sapiens_hsa012000.10451463
120Linoleic acid metabolism_Homo sapiens_hsa005910.09903628
121MicroRNAs in cancer_Homo sapiens_hsa052060.09582777
122beta-Alanine metabolism_Homo sapiens_hsa004100.09472785
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.09263896
124Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.08674222
125Viral myocarditis_Homo sapiens_hsa054160.07924878
126Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.07728753
127Bladder cancer_Homo sapiens_hsa052190.04828862
128Collecting duct acid secretion_Homo sapiens_hsa04966-0.0054847
129Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603-0.0050119
130Basal cell carcinoma_Homo sapiens_hsa05217-0.0046990
131Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.0045449
132Vitamin digestion and absorption_Homo sapiens_hsa04977-0.0005723

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