RFC5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* DNA strand elongation involved in DNA replication (GO:0006271)5.59275777
2DNA replication initiation (GO:0006270)5.47607605
3DNA unwinding involved in DNA replication (GO:0006268)5.34178283
4* DNA strand elongation (GO:0022616)5.30096629
5* telomere maintenance via semi-conservative replication (GO:0032201)5.24943358
6DNA replication checkpoint (GO:0000076)4.73218648
7* telomere maintenance via recombination (GO:0000722)4.61793758
8ribosomal small subunit assembly (GO:0000028)4.54386638
9* mitotic recombination (GO:0006312)4.44228063
10protein localization to kinetochore (GO:0034501)4.41777418
11maturation of SSU-rRNA (GO:0030490)4.40715691
12DNA replication-dependent nucleosome assembly (GO:0006335)4.35331684
13DNA replication-dependent nucleosome organization (GO:0034723)4.35331684
14DNA deamination (GO:0045006)4.32206603
15chromatin remodeling at centromere (GO:0031055)4.28460637
16viral transcription (GO:0019083)4.26791661
17CENP-A containing nucleosome assembly (GO:0034080)4.26322898
18translational termination (GO:0006415)4.20064014
19* telomere maintenance via telomere lengthening (GO:0010833)4.13471790
20ribosomal large subunit biogenesis (GO:0042273)4.08948977
21mitotic metaphase plate congression (GO:0007080)4.03079304
22nucleobase biosynthetic process (GO:0046112)4.02678106
23* nucleotide-excision repair, DNA gap filling (GO:0006297)4.02447972
24folic acid-containing compound biosynthetic process (GO:0009396)3.93384777
25DNA ligation (GO:0006266)3.89529300
26DNA replication-independent nucleosome assembly (GO:0006336)3.87103512
27DNA replication-independent nucleosome organization (GO:0034724)3.87103512
28ribosomal small subunit biogenesis (GO:0042274)3.85253568
29regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.82491990
30translational elongation (GO:0006414)3.81033863
31regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.78339667
32protein localization to chromosome, centromeric region (GO:0071459)3.77059824
33formation of translation preinitiation complex (GO:0001731)3.76797830
34mitotic nuclear envelope disassembly (GO:0007077)3.73712487
35kinetochore organization (GO:0051383)3.67201536
36translational initiation (GO:0006413)3.66915365
37purine nucleobase biosynthetic process (GO:0009113)3.63860881
38ribonucleoprotein complex biogenesis (GO:0022613)3.60681934
39IMP biosynthetic process (GO:0006188)3.59803022
40SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.57344405
41mitotic sister chromatid cohesion (GO:0007064)3.56879984
42metaphase plate congression (GO:0051310)3.56609790
43DNA topological change (GO:0006265)3.54835459
44non-recombinational repair (GO:0000726)3.53451449
45double-strand break repair via nonhomologous end joining (GO:0006303)3.53451449
46nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.52730405
47cotranslational protein targeting to membrane (GO:0006613)3.48639576
48spindle checkpoint (GO:0031577)3.47517989
49somatic diversification of immune receptors via somatic mutation (GO:0002566)3.47430116
50somatic hypermutation of immunoglobulin genes (GO:0016446)3.47430116
51protein targeting to ER (GO:0045047)3.46804528
52histone exchange (GO:0043486)3.45279862
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.44560989
54nuclear envelope disassembly (GO:0051081)3.43834020
55membrane disassembly (GO:0030397)3.43834020
56regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.42435851
57kinetochore assembly (GO:0051382)3.42262293
58mitotic sister chromatid segregation (GO:0000070)3.42003518
59deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.40063830
60ribosome biogenesis (GO:0042254)3.39183999
61regulation of chromosome segregation (GO:0051983)3.38899091
62regulation of double-strand break repair via homologous recombination (GO:0010569)3.38610368
63establishment of viral latency (GO:0019043)3.38390919
64spliceosomal snRNP assembly (GO:0000387)3.35935884
65DNA geometric change (GO:0032392)3.35025320
66DNA duplex unwinding (GO:0032508)3.34959295
67regulation of nuclear cell cycle DNA replication (GO:0033262)3.34820978
68negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.34783515
69negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.34783515
70negative regulation of mitotic sister chromatid segregation (GO:0033048)3.34783515
71negative regulation of mitotic sister chromatid separation (GO:2000816)3.34783515
72negative regulation of sister chromatid segregation (GO:0033046)3.34783515
73cellular protein complex disassembly (GO:0043624)3.34145650
74mitotic spindle checkpoint (GO:0071174)3.33499351
75rRNA processing (GO:0006364)3.33308119
76establishment of integrated proviral latency (GO:0075713)3.32150801
77attachment of spindle microtubules to kinetochore (GO:0008608)3.31521008
78* transcription-coupled nucleotide-excision repair (GO:0006283)3.30154899
79nuclear pore organization (GO:0006999)3.29764466
80chromosome segregation (GO:0007059)3.29707828
81regulation of centriole replication (GO:0046599)3.29617741
82establishment of protein localization to endoplasmic reticulum (GO:0072599)3.28118654
83mismatch repair (GO:0006298)3.27824836
84viral life cycle (GO:0019058)3.26021930
85establishment of chromosome localization (GO:0051303)3.25475178
86pore complex assembly (GO:0046931)3.25463965
87protein localization to endoplasmic reticulum (GO:0070972)3.25386274
88replication fork processing (GO:0031297)3.24175449
89regulation of DNA endoreduplication (GO:0032875)3.23818616
90rRNA metabolic process (GO:0016072)3.23206063
91mitotic spindle assembly checkpoint (GO:0007094)3.22283801
92mitotic chromosome condensation (GO:0007076)3.22129182
93IMP metabolic process (GO:0046040)3.21361992
94spindle assembly checkpoint (GO:0071173)3.20358396
95pseudouridine synthesis (GO:0001522)3.19260734
96positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.18826900
97regulation of mitotic metaphase/anaphase transition (GO:0030071)3.17433429
98regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.17433429
99L-serine metabolic process (GO:0006563)3.16096853
100negative regulation of ligase activity (GO:0051352)3.15292391
101negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.15292391
102regulation of mitotic spindle organization (GO:0060236)3.14858107
103proteasome assembly (GO:0043248)3.14447297
104* telomere organization (GO:0032200)3.13755196
105* telomere maintenance (GO:0000723)3.13679243
106ribosome assembly (GO:0042255)3.12355963
107regulation of helicase activity (GO:0051095)3.12051538
108sister chromatid segregation (GO:0000819)3.10133909
109regulation of sister chromatid segregation (GO:0033045)3.09916539
110regulation of mitotic sister chromatid separation (GO:0010965)3.09916539
111regulation of mitotic sister chromatid segregation (GO:0033047)3.09916539
112ATP-dependent chromatin remodeling (GO:0043044)3.07724780
113chromatin assembly or disassembly (GO:0006333)3.07322439
114spliceosomal complex assembly (GO:0000245)3.06185812
115maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.05690567
116DNA double-strand break processing (GO:0000729)3.05163000
117DNA catabolic process, exonucleolytic (GO:0000738)3.04902155
118* mitotic cell cycle (GO:0000278)3.04172918
119protein complex disassembly (GO:0043241)3.04063528
120chromosome condensation (GO:0030261)3.02529612
121G1/S transition of mitotic cell cycle (GO:0000082)3.02152714
122cell cycle G1/S phase transition (GO:0044843)3.02152714
123heterochromatin organization (GO:0070828)3.01955311
124mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.01630475
125positive regulation of chromosome segregation (GO:0051984)3.01479668
126intra-S DNA damage checkpoint (GO:0031573)3.01113948
127protein K6-linked ubiquitination (GO:0085020)2.97950382
128translation (GO:0006412)2.94928189
129regulation of spindle organization (GO:0090224)2.93453355
130nuclear pore complex assembly (GO:0051292)2.93289490
131nuclear-transcribed mRNA catabolic process (GO:0000956)2.92273965
132regulation of centrosome cycle (GO:0046605)2.92082786
133deoxyribonucleotide biosynthetic process (GO:0009263)2.91024901
134* DNA replication (GO:0006260)2.90566916
135meiotic chromosome segregation (GO:0045132)2.90015472
136macromolecular complex disassembly (GO:0032984)2.89400737
137viral mRNA export from host cell nucleus (GO:0046784)2.88856651
138base-excision repair (GO:0006284)2.87475702
139negative regulation of chromosome segregation (GO:0051985)2.86043160
140anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.84784860
141negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.84634748
142regulation of gene silencing by miRNA (GO:0060964)2.83961562

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse4.47261008
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.12950697
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.99617084
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.52737191
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.28573897
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.13782360
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.13551015
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.93421895
9MYC_18358816_ChIP-ChIP_MESCs_Mouse2.90417220
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.85271319
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.70294272
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.67856113
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.67439929
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.50761803
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.42154403
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34309097
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.34305882
18XRN2_22483619_ChIP-Seq_HELA_Human2.32220980
19VDR_23849224_ChIP-Seq_CD4+_Human2.14110714
20E2F1_21310950_ChIP-Seq_MCF-7_Human2.12676783
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.12670171
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.11688479
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.09089805
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06271681
25E2F7_22180533_ChIP-Seq_HELA_Human10.0680306
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.99990882
27AR_21909140_ChIP-Seq_LNCAP_Human1.99844228
28DCP1A_22483619_ChIP-Seq_HELA_Human1.95702649
29FOXP3_21729870_ChIP-Seq_TREG_Human1.94069641
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.91896087
31NANOG_18555785_ChIP-Seq_MESCs_Mouse1.90985968
32TTF2_22483619_ChIP-Seq_HELA_Human1.88002156
33* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.82065266
34* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.78241921
35THAP11_20581084_ChIP-Seq_MESCs_Mouse1.77894890
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.76991372
37GABP_19822575_ChIP-Seq_HepG2_Human1.71670110
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.71106362
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.66657375
40KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.63917045
41TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62709040
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60951696
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.59389416
44ELK1_19687146_ChIP-ChIP_HELA_Human1.56731971
45YY1_21170310_ChIP-Seq_MESCs_Mouse1.56558838
46EGR1_19374776_ChIP-ChIP_THP-1_Human1.56517445
47SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.55825542
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.55378254
49CIITA_25753668_ChIP-Seq_RAJI_Human1.52004410
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.51716581
51E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.49521591
52YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49386707
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49122436
54POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.46549256
55HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42660828
56SALL1_21062744_ChIP-ChIP_HESCs_Human1.40604201
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.34670809
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.34286948
59MYC_22102868_ChIP-Seq_BL_Human1.30354380
60KDM5A_27292631_Chip-Seq_BREAST_Human1.29681384
61ERG_20887958_ChIP-Seq_HPC-7_Mouse1.28472634
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.27431946
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25694135
64KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.23488243
65FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.20680181
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19839016
67* STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19702625
68KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.19105951
69KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.19105951
70KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.19105951
71PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.19010458
72TP63_19390658_ChIP-ChIP_HaCaT_Human1.18299401
73FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.16410376
74* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15633572
75RBPJ_22232070_ChIP-Seq_NCS_Mouse1.13945621
76CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.11248950
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.11158442
78NOTCH1_21737748_ChIP-Seq_TLL_Human1.10707936
79HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10137963
80CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09414713
81MYC_18940864_ChIP-ChIP_HL60_Human1.08897942
82TFEB_21752829_ChIP-Seq_HELA_Human1.06419760
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03931509
84PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02026972
85SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.01722732
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.99780447
87CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.99033200
88ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98907929
89TCF3_18692474_ChIP-Seq_MEFs_Mouse0.98363834
90KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97409476
91NANOG_16153702_ChIP-ChIP_HESCs_Human0.95543441
92PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94632040
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.93146759
94SOX2_16153702_ChIP-ChIP_HESCs_Human0.91727564
95DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89753888
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.89258257
97VDR_21846776_ChIP-Seq_THP-1_Human0.89078834
98CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86121122
99NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85235163
100* SPI1_23547873_ChIP-Seq_NB4_Human0.84677954
101EWS_26573619_Chip-Seq_HEK293_Human0.83984990
102CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.82920499
103HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.82372613
104BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.81731693
105POU5F1_16153702_ChIP-ChIP_HESCs_Human0.80891389
106* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.80305000
107* NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.79324080
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.78876584
109ESR1_15608294_ChIP-ChIP_MCF-7_Human0.78856070
110ELK1_22589737_ChIP-Seq_MCF10A_Human0.78758763
111OCT4_18692474_ChIP-Seq_MEFs_Mouse0.77995717
112* SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.76975239
113IRF1_19129219_ChIP-ChIP_H3396_Human0.76201410
114CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71025917
115* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.70934477
116NANOG_21062744_ChIP-ChIP_HESCs_Human0.70223140
117* CHD1_26751641_Chip-Seq_LNCaP_Human0.66309726
118FUS_26573619_Chip-Seq_HEK293_Human0.65426339

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.46682167
2MP0010094_abnormal_chromosome_stability5.25532974
3MP0003111_abnormal_nucleus_morphology4.83680005
4MP0004957_abnormal_blastocyst_morpholog4.54558614
5MP0008057_abnormal_DNA_replication4.49282693
6MP0003077_abnormal_cell_cycle4.15977934
7MP0008058_abnormal_DNA_repair3.67637377
8MP0008007_abnormal_cellular_replicative2.99417706
9MP0008932_abnormal_embryonic_tissue2.89421815
10MP0002396_abnormal_hematopoietic_system2.29881094
11MP0009697_abnormal_copulation2.29283753
12MP0003123_paternal_imprinting2.26494346
13MP0000350_abnormal_cell_proliferation2.24217045
14MP0001730_embryonic_growth_arrest2.20135754
15MP0000490_abnormal_crypts_of2.10554137
16MP0003786_premature_aging2.08560875
17MP0010352_gastrointestinal_tract_polyps1.98817551
18MP0008877_abnormal_DNA_methylation1.88242357
19MP0006292_abnormal_olfactory_placode1.78323082
20MP0010307_abnormal_tumor_latency1.76191787
21MP0000372_irregular_coat_pigmentation1.73726579
22MP0009379_abnormal_foot_pigmentation1.62995010
23MP0001697_abnormal_embryo_size1.62367273
24MP0005380_embryogenesis_phenotype1.57838624
25MP0001672_abnormal_embryogenesis/_devel1.57838624
26MP0002080_prenatal_lethality1.53735619
27MP0002085_abnormal_embryonic_tissue1.52252713
28MP0004133_heterotaxia1.51534547
29MP0002019_abnormal_tumor_incidence1.51399398
30MP0003718_maternal_effect1.50157366
31MP0000313_abnormal_cell_death1.48880443
32MP0006035_abnormal_mitochondrial_morpho1.45396225
33MP0002084_abnormal_developmental_patter1.36731112
34MP0003806_abnormal_nucleotide_metabolis1.36317319
35MP0003136_yellow_coat_color1.34281668
36MP0003984_embryonic_growth_retardation1.32381591
37MP0002210_abnormal_sex_determination1.32231080
38MP0004808_abnormal_hematopoietic_stem1.29935694
39MP0002088_abnormal_embryonic_growth/wei1.29135412
40MP0001529_abnormal_vocalization1.27786598
41MP0003315_abnormal_perineum_morphology1.27472463
42MP0001293_anophthalmia1.26825052
43MP0002086_abnormal_extraembryonic_tissu1.26348423
44MP0001346_abnormal_lacrimal_gland1.23425756
45MP0004197_abnormal_fetal_growth/weight/1.22080163
46MP0003567_abnormal_fetal_cardiomyocyte1.21082160
47MP0003121_genomic_imprinting1.20247983
48MP0004147_increased_porphyrin_level1.19482492
49MP0001145_abnormal_male_reproductive1.18968822
50MP0003890_abnormal_embryonic-extraembry1.17877948
51MP0008995_early_reproductive_senescence1.15217006
52MP0009333_abnormal_splenocyte_physiolog1.15167762
53MP0003763_abnormal_thymus_physiology1.14193550
54MP0000703_abnormal_thymus_morphology1.13825544
55MP0002697_abnormal_eye_size1.11363572
56MP0003941_abnormal_skin_development1.11290370
57MP0002234_abnormal_pharynx_morphology1.09272747
58MP0005397_hematopoietic_system_phenotyp1.06812529
59MP0001545_abnormal_hematopoietic_system1.06812529
60MP0005408_hypopigmentation1.05766768
61MP0005174_abnormal_tail_pigmentation1.05069369
62MP0010030_abnormal_orbit_morphology1.05019322
63MP0002398_abnormal_bone_marrow1.04921813
64MP0000858_altered_metastatic_potential1.04316992
65MP0006072_abnormal_retinal_apoptosis1.03293174
66MP0002722_abnormal_immune_system1.01659460
67MP0002160_abnormal_reproductive_system1.01256674
68MP0001929_abnormal_gametogenesis0.97928856
69MP0000689_abnormal_spleen_morphology0.97746031
70MP0000653_abnormal_sex_gland0.97554139
71MP0002653_abnormal_ependyma_morphology0.97231236
72MP0005075_abnormal_melanosome_morpholog0.96962604
73MP0002877_abnormal_melanocyte_morpholog0.93457454
74MP0002102_abnormal_ear_morphology0.91706058
75MP0000537_abnormal_urethra_morphology0.90510050
76MP0005171_absent_coat_pigmentation0.86848460
77MP0003119_abnormal_digestive_system0.86542896
78MP0002233_abnormal_nose_morphology0.84709324
79MP0002095_abnormal_skin_pigmentation0.83549315
80MP0005389_reproductive_system_phenotype0.82949972
81MP0005076_abnormal_cell_differentiation0.82480684
82MP0002429_abnormal_blood_cell0.82285809
83MP0001119_abnormal_female_reproductive0.81165312
84MP0003186_abnormal_redox_activity0.80688628
85MP0000358_abnormal_cell_content/0.80109446
86MP0002111_abnormal_tail_morphology0.79330898
87MP0003698_abnormal_male_reproductive0.78275717
88MP0003937_abnormal_limbs/digits/tail_de0.77885093
89MP0002075_abnormal_coat/hair_pigmentati0.77526396
90MP0001764_abnormal_homeostasis0.76867597
91MP0001188_hyperpigmentation0.76693177
92MP0000647_abnormal_sebaceous_gland0.76149209
93MP0005384_cellular_phenotype0.74469068
94MP0002163_abnormal_gland_morphology0.72405380
95MP0001727_abnormal_embryo_implantation0.71786722
96MP0001919_abnormal_reproductive_system0.70940396
97MP0002132_abnormal_respiratory_system0.70821692
98MP0002938_white_spotting0.70243702
99MP0000049_abnormal_middle_ear0.69914427
100MP0003861_abnormal_nervous_system0.68734682
101MP0000477_abnormal_intestine_morphology0.68583177
102MP0005621_abnormal_cell_physiology0.66768812
103MP0005391_vision/eye_phenotype0.66359516
104MP0000716_abnormal_immune_system0.65502408
105MP0001286_abnormal_eye_development0.65421898
106MP0008789_abnormal_olfactory_epithelium0.65055351
107MP0004233_abnormal_muscle_weight0.64751901
108MP0000631_abnormal_neuroendocrine_gland0.64470339
109MP0006054_spinal_hemorrhage0.64418185
110MP0002161_abnormal_fertility/fecundity0.63557783
111MP0000015_abnormal_ear_pigmentation0.62216145
112MP0005499_abnormal_olfactory_system0.62017963
113MP0005394_taste/olfaction_phenotype0.62017963
114MP0001186_pigmentation_phenotype0.61952833
115MP0003943_abnormal_hepatobiliary_system0.60376376
116MP0005501_abnormal_skin_physiology0.59688175
117MP0003699_abnormal_female_reproductive0.59392493
118MP0003755_abnormal_palate_morphology0.58467869
119MP0003221_abnormal_cardiomyocyte_apopto0.58438500
120MP0002092_abnormal_eye_morphology0.55866725
121MP0009053_abnormal_anal_canal0.55407079
122MP0001986_abnormal_taste_sensitivity0.53373723
123MP0005266_abnormal_metabolism0.53256492
124MP0002751_abnormal_autonomic_nervous0.52488260
125MP0000371_diluted_coat_color0.51448197
126MP0006036_abnormal_mitochondrial_physio0.51297440
127MP0009672_abnormal_birth_weight0.51263532
128MP0000465_gastrointestinal_hemorrhage0.50963966
129MP0001853_heart_inflammation0.50837785
130MP0009703_decreased_birth_body0.50603412

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.17795098
2Birth length less than 3rd percentile (HP:0003561)5.15130244
3Abnormality of cells of the erythroid lineage (HP:0012130)4.64193882
4Chromsome breakage (HP:0040012)4.64032887
5Chromosomal breakage induced by crosslinking agents (HP:0003221)4.63998936
6Abnormal number of erythroid precursors (HP:0012131)4.35799337
7Breast hypoplasia (HP:0003187)3.99708640
8Ependymoma (HP:0002888)3.54394388
9Oral leukoplakia (HP:0002745)3.52588469
10Abnormality of the preputium (HP:0100587)3.46364096
11Colon cancer (HP:0003003)3.44534069
12Abnormality of chromosome stability (HP:0003220)3.42778091
13Medulloblastoma (HP:0002885)3.40984288
14Meckel diverticulum (HP:0002245)3.36812093
15Agnosia (HP:0010524)3.33450083
16Pallor (HP:0000980)3.31338374
17Macrocytic anemia (HP:0001972)3.27646985
18Patellar aplasia (HP:0006443)3.24262239
19Abnormality of the ileum (HP:0001549)3.23577701
20Absent thumb (HP:0009777)3.20979086
21Aplasia/Hypoplasia of the uvula (HP:0010293)3.20292670
22Aplastic anemia (HP:0001915)3.13450720
23Selective tooth agenesis (HP:0001592)3.06703852
24Aplasia/Hypoplasia of the patella (HP:0006498)3.03044864
25Absent radius (HP:0003974)2.95179473
26Duplicated collecting system (HP:0000081)2.90709794
27Supernumerary spleens (HP:0009799)2.90068102
28Aplasia/Hypoplasia of the sacrum (HP:0008517)2.81489254
2911 pairs of ribs (HP:0000878)2.81311416
30Small intestinal stenosis (HP:0012848)2.79477322
31Duodenal stenosis (HP:0100867)2.79477322
32Acute necrotizing encephalopathy (HP:0006965)2.78358053
33Rough bone trabeculation (HP:0100670)2.76901475
34Myelodysplasia (HP:0002863)2.74930683
35Aplasia involving forearm bones (HP:0009822)2.74194115
36Absent forearm bone (HP:0003953)2.74194115
37Abnormal mitochondria in muscle tissue (HP:0008316)2.73666421
38Increased nuchal translucency (HP:0010880)2.71128845
39Rhabdomyosarcoma (HP:0002859)2.70611527
40Acute encephalopathy (HP:0006846)2.69567551
41Bone marrow hypocellularity (HP:0005528)2.68546741
42Volvulus (HP:0002580)2.68146493
43Abnormality of glycolysis (HP:0004366)2.62703524
44Horseshoe kidney (HP:0000085)2.58820884
45Abnormality of the renal collecting system (HP:0004742)2.57138503
46Triphalangeal thumb (HP:0001199)2.55976850
47Neoplasm of the pancreas (HP:0002894)2.55877256
48Premature graying of hair (HP:0002216)2.55327124
49Abnormal number of incisors (HP:0011064)2.53072292
50Cerebral hypomyelination (HP:0006808)2.52959886
51Increased serum pyruvate (HP:0003542)2.51449091
52Carpal bone hypoplasia (HP:0001498)2.50213044
53Microvesicular hepatic steatosis (HP:0001414)2.49613827
54Abnormality of the anterior horn cell (HP:0006802)2.45371806
55Degeneration of anterior horn cells (HP:0002398)2.45371806
56Increased CSF lactate (HP:0002490)2.44890485
57Sloping forehead (HP:0000340)2.44453630
58Basal cell carcinoma (HP:0002671)2.40166551
59Abnormality of the labia minora (HP:0012880)2.39939125
60Impulsivity (HP:0100710)2.39815424
61Asplenia (HP:0001746)2.35424582
62Abnormality of the duodenum (HP:0002246)2.33559218
63Abnormal lung lobation (HP:0002101)2.33418884
64Increased hepatocellular lipid droplets (HP:0006565)2.29439147
65Mitochondrial inheritance (HP:0001427)2.28456868
66Microretrognathia (HP:0000308)2.28416511
67Ectopic kidney (HP:0000086)2.27954759
68Abnormality of methionine metabolism (HP:0010901)2.27414193
69Tracheoesophageal fistula (HP:0002575)2.25922206
70Abnormality of DNA repair (HP:0003254)2.25675787
71Abnormality of abdominal situs (HP:0011620)2.22881515
72Abdominal situs inversus (HP:0003363)2.22881515
73Hepatocellular necrosis (HP:0001404)2.19836653
74Multiple enchondromatosis (HP:0005701)2.19624559
75Progressive macrocephaly (HP:0004481)2.18192313
76Pancytopenia (HP:0001876)2.17664804
77Cerebral edema (HP:0002181)2.17120750
78Increased serum lactate (HP:0002151)2.16706823
79Abnormality of pyrimidine metabolism (HP:0004353)2.13254772
80Abnormality of the carotid arteries (HP:0005344)2.12935715
81Aplasia/Hypoplasia of the spleen (HP:0010451)2.12036904
82Abnormality of cochlea (HP:0000375)2.10976159
83Short thumb (HP:0009778)2.10713694
84Neoplasm of the oral cavity (HP:0100649)2.06146437
85Trismus (HP:0000211)2.05775376
86Premature ovarian failure (HP:0008209)2.05726662
87Clubbing of toes (HP:0100760)2.05285557
88Cellular immunodeficiency (HP:0005374)2.04750129
89Hepatic necrosis (HP:0002605)2.03450380
90Lipid accumulation in hepatocytes (HP:0006561)2.03370161
91Neoplasm of striated muscle (HP:0009728)2.02494178
92Lymphoma (HP:0002665)2.02295412
93Cortical dysplasia (HP:0002539)2.02266644
94Squamous cell carcinoma (HP:0002860)2.01995185
95Cleft eyelid (HP:0000625)2.01179994
96Type I transferrin isoform profile (HP:0003642)2.00123402
97Abnormal trabecular bone morphology (HP:0100671)2.00117559
98Atresia of the external auditory canal (HP:0000413)1.99967614
99Missing ribs (HP:0000921)1.99556964
100Astrocytoma (HP:0009592)1.99529340
101Abnormality of the astrocytes (HP:0100707)1.99529340
102Megaloblastic anemia (HP:0001889)1.96181768
103Abnormality of reticulocytes (HP:0004312)1.95002861
104Amaurosis fugax (HP:0100576)1.94226080
105Glioma (HP:0009733)1.93643216
106Choanal atresia (HP:0000453)1.93347257
107Nephroblastoma (Wilms tumor) (HP:0002667)1.93255423
108Hypoplastic pelvis (HP:0008839)1.93023584
109Slender long bone (HP:0003100)1.92598873
110Secondary amenorrhea (HP:0000869)1.92432565
111Hypoplasia of the radius (HP:0002984)1.88385705
112Facial cleft (HP:0002006)1.88327912
113Thrombocytosis (HP:0001894)1.86253732
114Arteriovenous malformation (HP:0100026)1.86052890
115Neoplasm of the colon (HP:0100273)1.85794924
116Lactic acidosis (HP:0003128)1.85295704
117Cafe-au-lait spot (HP:0000957)1.85248791
118Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.83158305
119Aplasia/Hypoplasia of the sternum (HP:0006714)1.79524578
120Proximal placement of thumb (HP:0009623)1.78112047
121Embryonal renal neoplasm (HP:0011794)1.77718300
122Hypoplasia of the capital femoral epiphysis (HP:0003090)1.77544133
123Abnormality of homocysteine metabolism (HP:0010919)1.76973617
124Homocystinuria (HP:0002156)1.76973617
125Neoplasm of the adrenal gland (HP:0100631)1.75839422
126Abnormality of serum amino acid levels (HP:0003112)1.74654717
127Decreased activity of mitochondrial respiratory chain (HP:0008972)1.73156892
128Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.73156892
129Optic nerve coloboma (HP:0000588)1.72908940
130Postnatal microcephaly (HP:0005484)1.72773353
131Facial hemangioma (HP:0000329)1.71828382
132Duplication of thumb phalanx (HP:0009942)1.71735150
133Abnormality of the heme biosynthetic pathway (HP:0010472)1.69901946
134Morphological abnormality of the inner ear (HP:0011390)1.68983899
135Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.67084740
136Abnormality of alanine metabolism (HP:0010916)1.67084740
137Hyperalaninemia (HP:0003348)1.67084740
138Abnormality of aspartate family amino acid metabolism (HP:0010899)1.64249087

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.76056074
2BUB14.64284037
3CDC74.52862178
4EIF2AK13.67846446
5TLK13.20698003
6VRK22.93380658
7STK162.57008948
8SRPK12.52258897
9NEK22.42093201
10TTK2.40691374
11NME22.38951702
12VRK12.36621040
13ACVR1B2.10782867
14EIF2AK32.09147856
15CDK72.02636011
16PLK12.02342609
17RPS6KB21.83470479
18BRSK21.82017412
19MKNK11.81545755
20TESK21.80075615
21ATR1.76348099
22PLK41.74476031
23PASK1.69916714
24MKNK21.69187250
25AURKB1.64604775
26DYRK31.63966411
27TSSK61.63865273
28NEK11.62044468
29TRIM281.51810575
30CHEK21.49401560
31AURKA1.41949079
32MAP3K81.33067659
33RPS6KA41.29110456
34CCNB11.28877104
35EPHA21.26810744
36PLK31.26181577
37CDK121.26088919
38ZAK1.25919689
39SCYL21.23483117
40BRSK11.17446836
41CDK41.17286694
42TAF11.16856767
43STK41.16521534
44FLT31.15800571
45TGFBR11.11586851
46NUAK11.10745094
47PDK21.10135481
48PNCK1.09174125
49CHEK11.08100978
50EIF2AK21.05605639
51BMPR1B0.96370462
52PBK0.95926335
53STK100.95003835
54CDK80.92899565
55EEF2K0.91295456
56ATM0.88337672
57PAK40.86444983
58BRD40.80400218
59PIM10.79550940
60CDK20.77119863
61CLK10.74031063
62BLK0.73799146
63CSNK2A20.72763207
64BRAF0.71869373
65PRKCI0.69831730
66ERBB30.69106365
67PIM20.67965082
68CSNK2A10.66623420
69RPS6KA50.66154818
70MST1R0.65037882
71KDR0.64776073
72BCR0.62510214
73IRAK40.60247330
74YES10.59335200
75CSNK1G30.59333386
76PAK10.57503568
77MAP3K110.56993484
78CSNK1G10.56929029
79PLK20.56449438
80CDK10.55759804
81MAPKAPK30.52779944
82SMG10.52581179
83DYRK20.51307983
84MAP3K100.48934302
85NME10.46433433
86WNK30.46183469
87CSNK1A1L0.45139075
88STK30.44948414
89MAP4K10.44947434
90MELK0.43744892
91TNIK0.43462655
92GRK60.43116395
93TEC0.43111722
94CDK30.41961182
95MAP2K30.37453701
96MAP4K20.36637006
97BTK0.35437332
98ERBB40.34514520
99MST40.34315678
100MAP2K70.34241251
101TAOK20.34201747
102BCKDK0.34178412
103TESK10.33730022
104CSNK1G20.33114524
105IRAK30.32077242
106ALK0.31494432
107PRKDC0.30574799
108CDK60.30481942
109AKT20.30370558
110MAPKAPK50.29445999
111RAF10.28031828
112CDK180.27930717
113CDK140.27492986
114CSNK1E0.26869326
115DAPK10.26532807
116MINK10.26247230
117CDK11A0.25287359
118CDK150.24845440
119PKN20.23434873
120LYN0.22725594
121MAP3K40.22069364
122CDK190.21675337
123KIT0.21584161
124LRRK20.20846758
125CDK90.20033486
126MAPK110.18310832
127MAPK140.17974635
128AKT10.15981592
129CSNK1D0.15752849

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030305.67578428
2* Mismatch repair_Homo sapiens_hsa034304.79203257
3Ribosome_Homo sapiens_hsa030103.88028816
4Homologous recombination_Homo sapiens_hsa034403.46470938
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.33357694
6Base excision repair_Homo sapiens_hsa034103.30100434
7Spliceosome_Homo sapiens_hsa030403.26207365
8* Nucleotide excision repair_Homo sapiens_hsa034203.08423061
9RNA polymerase_Homo sapiens_hsa030203.05297316
10One carbon pool by folate_Homo sapiens_hsa006702.87146598
11Proteasome_Homo sapiens_hsa030502.86531019
12RNA transport_Homo sapiens_hsa030132.84940817
13Cell cycle_Homo sapiens_hsa041102.71932469
14Fanconi anemia pathway_Homo sapiens_hsa034602.60342090
15Pyrimidine metabolism_Homo sapiens_hsa002402.59988525
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.49457878
17Non-homologous end-joining_Homo sapiens_hsa034502.13755257
18RNA degradation_Homo sapiens_hsa030181.86077278
19Basal transcription factors_Homo sapiens_hsa030221.82854412
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.67903399
21p53 signaling pathway_Homo sapiens_hsa041151.63286867
22mRNA surveillance pathway_Homo sapiens_hsa030151.53167066
23Systemic lupus erythematosus_Homo sapiens_hsa053221.53098455
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.44815617
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.40050004
26Purine metabolism_Homo sapiens_hsa002301.34674038
27Pyruvate metabolism_Homo sapiens_hsa006201.33530764
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.32180642
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.21964098
30Propanoate metabolism_Homo sapiens_hsa006401.06348546
31Fatty acid elongation_Homo sapiens_hsa000621.03565422
32Epstein-Barr virus infection_Homo sapiens_hsa051691.03007522
33Vitamin B6 metabolism_Homo sapiens_hsa007501.02655243
34Folate biosynthesis_Homo sapiens_hsa007901.00835178
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.97895776
36Viral carcinogenesis_Homo sapiens_hsa052030.91639167
37Herpes simplex infection_Homo sapiens_hsa051680.90830058
38Steroid biosynthesis_Homo sapiens_hsa001000.90236422
39Oocyte meiosis_Homo sapiens_hsa041140.85391382
40Protein export_Homo sapiens_hsa030600.85002073
41Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.81290203
42Sulfur relay system_Homo sapiens_hsa041220.79602681
43Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79059567
44Antigen processing and presentation_Homo sapiens_hsa046120.76433383
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75475985
46Cyanoamino acid metabolism_Homo sapiens_hsa004600.74691207
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73588819
48Alcoholism_Homo sapiens_hsa050340.68434048
49Huntingtons disease_Homo sapiens_hsa050160.67934209
50HTLV-I infection_Homo sapiens_hsa051660.65705171
51Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58225941
52Pentose phosphate pathway_Homo sapiens_hsa000300.57913350
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.56859741
54Thyroid cancer_Homo sapiens_hsa052160.56786162
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56419373
56Drug metabolism - other enzymes_Homo sapiens_hsa009830.56378015
57Primary immunodeficiency_Homo sapiens_hsa053400.55992847
58Selenocompound metabolism_Homo sapiens_hsa004500.53996553
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53745116
60Biosynthesis of amino acids_Homo sapiens_hsa012300.53197766
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.52062705
62Transcriptional misregulation in cancer_Homo sapiens_hsa052020.51096822
63Lysine degradation_Homo sapiens_hsa003100.50979901
64Glutathione metabolism_Homo sapiens_hsa004800.50534180
65Parkinsons disease_Homo sapiens_hsa050120.49480706
66MicroRNAs in cancer_Homo sapiens_hsa052060.47655581
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.44686819
68Fatty acid metabolism_Homo sapiens_hsa012120.44287415
69Legionellosis_Homo sapiens_hsa051340.42309625
70Small cell lung cancer_Homo sapiens_hsa052220.42054677
71N-Glycan biosynthesis_Homo sapiens_hsa005100.41234459
72Apoptosis_Homo sapiens_hsa042100.38855979
73Bladder cancer_Homo sapiens_hsa052190.38423135
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37719059
75Measles_Homo sapiens_hsa051620.36693261
76Oxidative phosphorylation_Homo sapiens_hsa001900.32987690
77Butanoate metabolism_Homo sapiens_hsa006500.32911177
78Shigellosis_Homo sapiens_hsa051310.30509400
79Hematopoietic cell lineage_Homo sapiens_hsa046400.30374719
80Hepatitis B_Homo sapiens_hsa051610.29989229
81NF-kappa B signaling pathway_Homo sapiens_hsa040640.29498019
82Basal cell carcinoma_Homo sapiens_hsa052170.29309403
83Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28586087
84Colorectal cancer_Homo sapiens_hsa052100.27626337
85TGF-beta signaling pathway_Homo sapiens_hsa043500.27167278
86Peroxisome_Homo sapiens_hsa041460.25055774
87Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.22981042
88Cardiac muscle contraction_Homo sapiens_hsa042600.22721738
89Arginine and proline metabolism_Homo sapiens_hsa003300.21829160
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21428722
91RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.21316292
92Metabolic pathways_Homo sapiens_hsa011000.20416005
93Pathways in cancer_Homo sapiens_hsa052000.19191777
94Hippo signaling pathway_Homo sapiens_hsa043900.18239729
95NOD-like receptor signaling pathway_Homo sapiens_hsa046210.17346394
96Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.16615962
97Other glycan degradation_Homo sapiens_hsa005110.16344838
98Influenza A_Homo sapiens_hsa051640.16084598
99Notch signaling pathway_Homo sapiens_hsa043300.15466983
100Carbon metabolism_Homo sapiens_hsa012000.15225272
101Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.14872789
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.13551223
103Arachidonic acid metabolism_Homo sapiens_hsa005900.13311593
104Acute myeloid leukemia_Homo sapiens_hsa052210.13264340
105Galactose metabolism_Homo sapiens_hsa000520.13184260
106Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.13136490
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.12440178
108Sulfur metabolism_Homo sapiens_hsa009200.11211808
109Chronic myeloid leukemia_Homo sapiens_hsa052200.11074815
110Fructose and mannose metabolism_Homo sapiens_hsa000510.10851030
111Melanoma_Homo sapiens_hsa052180.10538230
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.08845186
113Prostate cancer_Homo sapiens_hsa052150.08375709
114Renin-angiotensin system_Homo sapiens_hsa046140.08320144
115HIF-1 signaling pathway_Homo sapiens_hsa040660.07710031
116Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.07312091
117Alzheimers disease_Homo sapiens_hsa050100.06505852
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.06466683
119Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.06457617
120Hedgehog signaling pathway_Homo sapiens_hsa043400.06102904
121Asthma_Homo sapiens_hsa053100.05736134
122Tyrosine metabolism_Homo sapiens_hsa003500.05464188
123Fatty acid degradation_Homo sapiens_hsa000710.04821148
124Wnt signaling pathway_Homo sapiens_hsa043100.04615059
125Arginine biosynthesis_Homo sapiens_hsa002200.02332524
126Nitrogen metabolism_Homo sapiens_hsa009100.02102718

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