RGL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of mononuclear cell migration (GO:0071675)4.42762250
2regulation of fever generation (GO:0031620)3.97789193
3positive regulation of heat generation (GO:0031652)3.81077171
4regulation of vitamin D biosynthetic process (GO:0060556)3.55600581
5negative regulation of interleukin-12 production (GO:0032695)3.50849959
6locomotory exploration behavior (GO:0035641)3.45970878
7virion attachment to host cell (GO:0019062)3.42704959
8adhesion of symbiont to host cell (GO:0044650)3.42704959
9synaptic vesicle maturation (GO:0016188)3.37220631
10negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.35012963
11cellular response to thyroid hormone stimulus (GO:0097067)3.33892208
12regulation of macrophage chemotaxis (GO:0010758)3.33292539
13adhesion of symbiont to host (GO:0044406)3.22649542
14regulation of heat generation (GO:0031650)3.17607787
15glycosphingolipid catabolic process (GO:0046479)3.16116469
16regulation of cytokine secretion involved in immune response (GO:0002739)3.14613358
17T-helper 1 type immune response (GO:0042088)3.05185775
18regulation of T-helper 1 cell differentiation (GO:0045625)3.01545729
19synaptic vesicle docking involved in exocytosis (GO:0016081)3.00608708
20positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.99377098
21lipopolysaccharide-mediated signaling pathway (GO:0031663)2.94500014
22regulation of membrane protein ectodomain proteolysis (GO:0051043)2.91717404
23sodium ion export (GO:0071436)2.91514998
24positive regulation of type 2 immune response (GO:0002830)2.89441885
25cellular potassium ion homeostasis (GO:0030007)2.88907265
26oligosaccharide catabolic process (GO:0009313)2.88519558
27axon extension involved in axon guidance (GO:0048846)2.86099509
28neuron projection extension involved in neuron projection guidance (GO:1902284)2.86099509
29proline transport (GO:0015824)2.85537947
30regulation of short-term neuronal synaptic plasticity (GO:0048172)2.85356878
31positive regulation of chemokine biosynthetic process (GO:0045080)2.82149082
32regulation of chronic inflammatory response (GO:0002676)2.80706686
33glycolipid catabolic process (GO:0019377)2.79127356
34positive regulation of macrophage cytokine production (GO:0060907)2.77537727
35negative regulation of nitric oxide biosynthetic process (GO:0045019)2.73130048
36branching involved in labyrinthine layer morphogenesis (GO:0060670)2.72880476
37regulation of podosome assembly (GO:0071801)2.72782418
38vascular endothelial growth factor signaling pathway (GO:0038084)2.72674686
39regulation of vitamin metabolic process (GO:0030656)2.69320274
40positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.68964686
41cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.68427808
42regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.67662225
43barbed-end actin filament capping (GO:0051016)2.66407831
44response to peptidoglycan (GO:0032494)2.64494475
45regulation of synapse structural plasticity (GO:0051823)2.64421531
46apoptotic cell clearance (GO:0043277)2.63936178
47type I interferon signaling pathway (GO:0060337)2.63275824
48cellular response to type I interferon (GO:0071357)2.63275824
49interferon-gamma-mediated signaling pathway (GO:0060333)2.61262083
50macrophage activation involved in immune response (GO:0002281)2.59779764
51regulation of glutamate receptor signaling pathway (GO:1900449)2.58490511
52response to type I interferon (GO:0034340)2.58382034
53modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.53364158
54positive regulation by organism of defense response of other organism involved in symbiotic interact2.53364158
55modulation by symbiont of host immune response (GO:0052553)2.53364158
56positive regulation by symbiont of host defense response (GO:0052509)2.53364158
57modulation by symbiont of host defense response (GO:0052031)2.53364158
58modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.53364158
59regulation of nitric oxide biosynthetic process (GO:0045428)2.52579008
60positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.51710207
61vocalization behavior (GO:0071625)2.51000184
62cell communication by electrical coupling (GO:0010644)2.50885610
63myeloid dendritic cell differentiation (GO:0043011)2.48148911
64ceramide catabolic process (GO:0046514)2.46841118
65glutamate secretion (GO:0014047)2.46393335
66synaptic vesicle exocytosis (GO:0016079)2.45042597
67potassium ion import (GO:0010107)2.44933899
68positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.44853317
69monocyte chemotaxis (GO:0002548)2.43651133
70positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.41999296
71regulation of type 2 immune response (GO:0002828)2.41285082
72clathrin coat assembly (GO:0048268)2.41277430
73keratan sulfate catabolic process (GO:0042340)2.40157141
74regulation of interferon-alpha production (GO:0032647)2.40136805
75positive regulation of nitric oxide biosynthetic process (GO:0045429)2.38796691
76cellular response to lipopolysaccharide (GO:0071222)2.37915537
77germinal center formation (GO:0002467)2.36345856
78alanine transport (GO:0032328)2.36182807
79exploration behavior (GO:0035640)2.35323459
80regulation of chemokine biosynthetic process (GO:0045073)2.34479760
81retina vasculature morphogenesis in camera-type eye (GO:0061299)2.34328416
82activation of protein kinase A activity (GO:0034199)2.34072364
83amino sugar catabolic process (GO:0046348)2.33383375
84stress fiber assembly (GO:0043149)2.32068853
85regulation of synaptic vesicle exocytosis (GO:2000300)2.31276365
86plasma membrane repair (GO:0001778)2.30224840
87Rap protein signal transduction (GO:0032486)2.30087339
88positive regulation of fibroblast migration (GO:0010763)2.30044640
89negative regulation of lipid storage (GO:0010888)2.29481936
90response to thyroid hormone (GO:0097066)2.28536810
91cellular response to molecule of bacterial origin (GO:0071219)2.28276433
92regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.28027576
93regulation of ARF protein signal transduction (GO:0032012)2.27054503
94negative regulation of cytokine production involved in immune response (GO:0002719)2.26756067
95glial cell migration (GO:0008347)2.24816254
96regulation of dendritic cell antigen processing and presentation (GO:0002604)2.22324705
97membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.22111644
98L-amino acid import (GO:0043092)2.21858353
99regulation of T-helper 2 cell differentiation (GO:0045628)2.21606924
100negative regulation of vascular permeability (GO:0043116)2.21253842
101bone resorption (GO:0045453)2.20452145
102G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.20417075
103cellular response to ethanol (GO:0071361)2.20059337
104layer formation in cerebral cortex (GO:0021819)2.19754673
105positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.18327171
106regulation of macrophage cytokine production (GO:0010935)2.17513058
107membrane lipid catabolic process (GO:0046466)2.17265749
108insulin-like growth factor receptor signaling pathway (GO:0048009)2.16806996
109regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.15631510
110positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.15183265
111regulation of interleukin-8 biosynthetic process (GO:0045414)2.15108432
112positive regulation of acute inflammatory response (GO:0002675)2.14106070
113negative regulation of production of molecular mediator of immune response (GO:0002701)2.14099201
114neurotransmitter-gated ion channel clustering (GO:0072578)2.13273650
115regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.13186760
116response to lipoprotein particle (GO:0055094)2.13055248
117cellular response to interferon-alpha (GO:0035457)2.12592108
118cellular sodium ion homeostasis (GO:0006883)2.11986081
119regulation of neuronal synaptic plasticity (GO:0048168)2.11687302
120positive regulation of smooth muscle cell migration (GO:0014911)2.11499760
121cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.11208402
122regulation of synaptic vesicle transport (GO:1902803)2.10217476
123regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.10053349
124protein localization to endosome (GO:0036010)2.09753359
125positive regulation of neurotransmitter secretion (GO:0001956)2.08737015
126response to nerve growth factor (GO:1990089)2.07907577
127cellular response to nerve growth factor stimulus (GO:1990090)2.07907577
128basement membrane organization (GO:0071711)2.07895302
129lymph vessel development (GO:0001945)2.07748400
130regulation of dendritic spine morphogenesis (GO:0061001)2.07720631
131regulation of long-term neuronal synaptic plasticity (GO:0048169)2.07698898
132positive regulation of cAMP-mediated signaling (GO:0043950)2.06946164
133dendrite morphogenesis (GO:0048813)2.06736660
134immunoglobulin mediated immune response (GO:0016064)2.06651563
135ionotropic glutamate receptor signaling pathway (GO:0035235)2.06109113
136regulation of early endosome to late endosome transport (GO:2000641)2.06034618
137positive regulation of cholesterol efflux (GO:0010875)2.04608631
138N-acetylneuraminate metabolic process (GO:0006054)2.04173275
139low-density lipoprotein particle clearance (GO:0034383)2.03307906
140cellular response to interferon-gamma (GO:0071346)2.03085588
141amino acid import (GO:0043090)2.02546448
142dendritic cell differentiation (GO:0097028)2.00619600
143regulation of cholesterol storage (GO:0010885)1.99378435
144sphingolipid catabolic process (GO:0030149)1.99338740
145negative regulation of amyloid precursor protein catabolic process (GO:1902992)1.99286934
146vesicle transport along microtubule (GO:0047496)1.99243437
147eosinophil chemotaxis (GO:0048245)1.99007173
148positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)1.98813602
149regulation of tumor necrosis factor biosynthetic process (GO:0042534)1.98334360
150semaphorin-plexin signaling pathway (GO:0071526)1.96646826
151regulation of interferon-beta biosynthetic process (GO:0045357)1.96542479
152nerve growth factor signaling pathway (GO:0038180)1.96282169
153establishment of nucleus localization (GO:0040023)1.96134557
154cytoskeletal anchoring at plasma membrane (GO:0007016)1.95750427
155positive regulation of phosphoprotein phosphatase activity (GO:0032516)1.95340979
156positive regulation of axon extension (GO:0045773)1.94801560
157membrane repolarization during cardiac muscle cell action potential (GO:0086013)1.93348020
158antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G1.93067083
159relaxation of cardiac muscle (GO:0055119)1.93048052
160regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 1.92907648
161microglial cell activation (GO:0001774)1.91772406
162positive regulation of muscle hypertrophy (GO:0014742)1.91192530
163positive regulation of cardiac muscle hypertrophy (GO:0010613)1.91192530
164negative regulation of amino acid transport (GO:0051956)1.90389380
165cell adhesion mediated by integrin (GO:0033627)1.89897090
166positive regulation of synaptic transmission, glutamatergic (GO:0051968)1.89856235
167peptidyl-tyrosine autophosphorylation (GO:0038083)1.89788844
168substrate-dependent cell migration (GO:0006929)1.89295953
169vascular endothelial growth factor receptor signaling pathway (GO:0048010)1.89286002
170neurotransmitter secretion (GO:0007269)1.89187341
171regulation of clathrin-mediated endocytosis (GO:2000369)1.89082509
172dendritic spine morphogenesis (GO:0060997)1.88964070
173neuromuscular process controlling balance (GO:0050885)1.88740563
174macrophage activation (GO:0042116)1.88382302
175cAMP biosynthetic process (GO:0006171)1.88265190
176positive regulation of p38MAPK cascade (GO:1900745)1.87749426
177blood vessel maturation (GO:0001955)1.87726900
178regulation of dendritic spine development (GO:0060998)1.87502901
179detection of molecule of bacterial origin (GO:0032490)1.87104215
180membrane repolarization (GO:0086009)1.86831596
181regulation of ARF GTPase activity (GO:0032312)1.86713578
182ovulation from ovarian follicle (GO:0001542)1.86667735
183positive regulation of cellular amide metabolic process (GO:0034250)1.86515597
184adenosine receptor signaling pathway (GO:0001973)1.85604771

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human2.96959491
2IRF8_22096565_ChIP-ChIP_GC-B_Human2.79206608
3IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.17643807
4NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.13911754
5RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.13567437
6* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.13088906
7* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.12533970
8GBX2_23144817_ChIP-Seq_PC3_Human2.10543317
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.03685510
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.03685510
11* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.98190985
12DROSHA_22980978_ChIP-Seq_HELA_Human1.96174349
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.94670598
14* SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.91980646
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.89935847
16NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.89738048
17CDX2_19796622_ChIP-Seq_MESCs_Mouse1.84285407
18* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.81999528
19* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.77627779
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.77483439
21TRIM28_21343339_ChIP-Seq_HEK293_Human1.73945739
22EED_16625203_ChIP-ChIP_MESCs_Mouse1.71673531
23FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.71001496
24JARID2_20075857_ChIP-Seq_MESCs_Mouse1.70972856
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.60906002
26BP1_19119308_ChIP-ChIP_Hs578T_Human1.59425344
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.54228825
28GATA2_21666600_ChIP-Seq_HMVEC_Human1.49030282
29* RNF2_27304074_Chip-Seq_ESCs_Mouse1.48005698
30* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.46042178
31STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.45708134
32* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.45562351
33NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.43808647
34ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43744774
35SMAD_19615063_ChIP-ChIP_OVARY_Human1.43248090
36EP300_21415370_ChIP-Seq_HL-1_Mouse1.43060359
37Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.42526786
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.41325020
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.40131021
40* EZH2_27294783_Chip-Seq_ESCs_Mouse1.36859817
41TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.34594220
42RARB_27405468_Chip-Seq_BRAIN_Mouse1.33048787
43WT1_25993318_ChIP-Seq_PODOCYTE_Human1.32740873
44VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.29936161
45WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.28226353
46* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.27936368
47* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27546387
48BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.24129293
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.24102086
50MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.24089529
51AHR_22903824_ChIP-Seq_MCF-7_Human1.22766941
52GATA1_22025678_ChIP-Seq_K562_Human1.21714418
53SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21028899
54RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20325798
55RXR_22108803_ChIP-Seq_LS180_Human1.20240400
56* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.19650139
57NFIB_24661679_ChIP-Seq_LUNG_Mouse1.18212114
58PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.18162327
59* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.16917890
60* SMAD4_21799915_ChIP-Seq_A2780_Human1.16535110
61ARNT_22903824_ChIP-Seq_MCF-7_Human1.16487306
62PIAS1_25552417_ChIP-Seq_VCAP_Human1.16283034
63IRF8_27001747_Chip-Seq_BMDM_Mouse1.15650269
64STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.15611052
65PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.15110452
66ESR2_21235772_ChIP-Seq_MCF-7_Human1.15025267
67NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.14746859
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.14746859
69KDM2B_26808549_Chip-Seq_K562_Human1.14373497
70EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12987112
71SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11736183
72RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10805274
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.09763047
74TP53_16413492_ChIP-PET_HCT116_Human1.09481109
75EGR1_19374776_ChIP-ChIP_THP-1_Human1.09336828
76SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08786288
77VDR_24787735_ChIP-Seq_THP-1_Human1.08399152
78IRF8_21731497_ChIP-ChIP_J774_Mouse1.07996866
79SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06810757
80AR_21572438_ChIP-Seq_LNCaP_Human1.05989914
81* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.05929375
82CJUN_26792858_Chip-Seq_BT549_Human1.05753709
83REST_21632747_ChIP-Seq_MESCs_Mouse1.05009976
84TP53_18474530_ChIP-ChIP_U2OS_Human1.04430483
85WT1_19549856_ChIP-ChIP_CCG9911_Human1.04278267
86TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03451394
87* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.03159526
88ESR1_21235772_ChIP-Seq_MCF-7_Human1.03074300
89IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.00939867
90* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.00431274
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00266989
92GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98859886
93SMAD3_21741376_ChIP-Seq_HESCs_Human0.98266954
94PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.97807303
95SOX2_21211035_ChIP-Seq_LN229_Gbm0.97747525
96EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97203135
97* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96900276
98AR_25329375_ChIP-Seq_VCAP_Human0.96346574
99ESR1_20079471_ChIP-ChIP_T-47D_Human0.94456505
100RING1B_27294783_Chip-Seq_ESCs_Mouse0.94414199
101AR_19668381_ChIP-Seq_PC3_Human0.94188123
102* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93873905
103* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.93172501
104SMAD4_21741376_ChIP-Seq_HESCs_Human0.92531997
105ERG_21242973_ChIP-ChIP_JURKAT_Human0.92005164
106SPI1_23127762_ChIP-Seq_K562_Human0.91993567
107MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91668169
108* PU_27001747_Chip-Seq_BMDM_Mouse0.91177626
109CTNNB1_20460455_ChIP-Seq_HCT116_Human0.90934512
110EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.90888721
111NR3C1_21868756_ChIP-Seq_MCF10A_Human0.89933224
112FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.88518151
113NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87969699
114DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.87853759
115CLOCK_20551151_ChIP-Seq_293T_Human0.87435578
116* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87414860
117* LXR_22158963_ChIP-Seq_LIVER_Mouse0.86722802
118BCAT_22108803_ChIP-Seq_LS180_Human0.86332500
119* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.85672714
120MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.85330436
121TBX20_22328084_ChIP-Seq_HEART_Mouse0.85283136
122TBX20_22080862_ChIP-Seq_HEART_Mouse0.85283136
123SMAD3_21741376_ChIP-Seq_EPCs_Human0.84737444
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84236907
125PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.83529254
126TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.83037727
127STAT3_23295773_ChIP-Seq_U87_Human0.82965678
128TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.82934625
129* FOXA2_19822575_ChIP-Seq_HepG2_Human0.81809662
130* SOX2_20726797_ChIP-Seq_SW620_Human0.81612627
131* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.81564746
132P300_19829295_ChIP-Seq_ESCs_Human0.81540924
133STAT4_19710469_ChIP-ChIP_TH1__Mouse0.80144511
134GATA1_19941826_ChIP-Seq_K562_Human0.78881479

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.28348956
2MP0006082_CNS_inflammation3.27872573
3MP0008438_abnormal_cutaneous_collagen3.24905343
4MP0009840_abnormal_foam_cell2.92196929
5MP0009780_abnormal_chondrocyte_physiolo2.61527489
6MP0000569_abnormal_digit_pigmentation2.59834494
7MP0004858_abnormal_nervous_system2.48757592
8MP0010368_abnormal_lymphatic_system2.45412767
9MP0005167_abnormal_blood-brain_barrier2.43909060
10MP0001958_emphysema2.41951086
11MP0006054_spinal_hemorrhage2.41672349
12MP0004272_abnormal_basement_membrane2.39260571
13MP0005058_abnormal_lysosome_morphology2.34200569
14MP0002148_abnormal_hypersensitivity_rea2.24511902
15MP0003303_peritoneal_inflammation2.19794150
16MP0009785_altered_susceptibility_to2.07186055
17MP0000920_abnormal_myelination2.07048467
18MP0001879_abnormal_lymphatic_vessel1.99670766
19MP0008004_abnormal_stomach_pH1.98169248
20MP0003635_abnormal_synaptic_transmissio1.98151440
21MP0003705_abnormal_hypodermis_morpholog1.96246943
22MP0004510_myositis1.94582143
23MP0003075_altered_response_to1.90601903
24MP0003172_abnormal_lysosome_physiology1.90416787
25MP0003690_abnormal_glial_cell1.77145620
26MP0003300_gastrointestinal_ulcer1.75938256
27MP0003436_decreased_susceptibility_to1.74536817
28MP0002419_abnormal_innate_immunity1.71198230
29MP0001790_abnormal_immune_system1.71053608
30MP0005387_immune_system_phenotype1.71053608
31MP0003045_fibrosis1.70057825
32MP0009764_decreased_sensitivity_to1.67962592
33MP0002139_abnormal_hepatobiliary_system1.67962043
34MP0004130_abnormal_muscle_cell1.67866748
35MP0005670_abnormal_white_adipose1.65970271
36MP0003279_aneurysm1.65888545
37MP0005623_abnormal_meninges_morphology1.60428769
38MP0008961_abnormal_basal_metabolism1.58907945
39MP0000604_amyloidosis1.57439392
40MP0000013_abnormal_adipose_tissue1.56762467
41MP0002063_abnormal_learning/memory/cond1.56139311
42MP0001501_abnormal_sleep_pattern1.54575787
43MP0005000_abnormal_immune_tolerance1.54379048
44MP0002064_seizures1.52387657
45MP0001835_abnormal_antigen_presentation1.51192455
46MP0005275_abnormal_skin_tensile1.43998846
47MP0000751_myopathy1.40915607
48MP0005503_abnormal_tendon_morphology1.40551501
49MP0002998_abnormal_bone_remodeling1.40050658
50MP0005025_abnormal_response_to1.38766640
51MP0009745_abnormal_behavioral_response1.38039898
52MP0003329_amyloid_beta_deposits1.36193913
53MP0003724_increased_susceptibility_to1.36140193
54MP0002332_abnormal_exercise_endurance1.34643752
55MP0003448_altered_tumor_morphology1.34605407
56MP0009046_muscle_twitch1.33619785
57MP0003191_abnormal_cellular_cholesterol1.30073795
58MP0003453_abnormal_keratinocyte_physiol1.26936398
59MP0004484_altered_response_of1.26546611
60MP0003633_abnormal_nervous_system1.23491299
61MP0002295_abnormal_pulmonary_circulatio1.22391514
62MP0002168_other_aberrant_phenotype1.22335987
63MP0003828_pulmonary_edema1.22164013
64MP0002909_abnormal_adrenal_gland1.21161870
65MP0004270_analgesia1.20152971
66MP0000343_altered_response_to1.19423509
67MP0001968_abnormal_touch/_nociception1.18284375
68MP0001542_abnormal_bone_strength1.16204367
69MP0004084_abnormal_cardiac_muscle1.16018348
70MP0005671_abnormal_response_to1.15777147
71MP0003091_abnormal_cell_migration1.15674399
72MP0003880_abnormal_central_pattern1.14108417
73MP0005451_abnormal_body_composition1.13928941
74MP0005166_decreased_susceptibility_to1.12893534
75MP0002572_abnormal_emotion/affect_behav1.12363868
76MP0002452_abnormal_antigen_presenting1.12315289
77MP0002896_abnormal_bone_mineralization1.10221493
78MP0002837_dystrophic_cardiac_calcinosis1.09561152
79MP0004947_skin_inflammation1.06896433
80MP0005257_abnormal_intraocular_pressure1.06273317
81MP0000685_abnormal_immune_system1.04635159
82MP0002877_abnormal_melanocyte_morpholog1.02918856
83MP0001765_abnormal_ion_homeostasis1.02158628
84MP0005595_abnormal_vascular_smooth1.01342931
85MP0001845_abnormal_inflammatory_respons1.01089409
86MP0010386_abnormal_urinary_bladder1.00802085
87MP0004043_abnormal_pH_regulation1.00589339
88MP0002723_abnormal_immune_serum1.00244943
89MP0002736_abnormal_nociception_after0.99586369
90MP0002972_abnormal_cardiac_muscle0.98182899
91MP0001486_abnormal_startle_reflex0.97903667
92MP0001756_abnormal_urination0.97795521
93MP0003566_abnormal_cell_adhesion0.97666239
94MP0008469_abnormal_protein_level0.97128451
95MP0001440_abnormal_grooming_behavior0.96876976
96MP0003879_abnormal_hair_cell0.94887080
97MP0004215_abnormal_myocardial_fiber0.94482857
98MP0005310_abnormal_salivary_gland0.94245607
99MP0005375_adipose_tissue_phenotype0.93275052
100MP0005666_abnormal_adipose_tissue0.93046070
101MP0006138_congestive_heart_failure0.92722574
102MP0000767_abnormal_smooth_muscle0.92371751
103MP0003632_abnormal_nervous_system0.92212338
104MP0005535_abnormal_body_temperature0.91617599
105MP0001533_abnormal_skeleton_physiology0.90582785
106MP0001853_heart_inflammation0.89788593
107MP0001545_abnormal_hematopoietic_system0.89720956
108MP0005397_hematopoietic_system_phenotyp0.89720956
109MP0000003_abnormal_adipose_tissue0.89151883
110MP0005023_abnormal_wound_healing0.88993620
111MP0003283_abnormal_digestive_organ0.87964117
112MP0004036_abnormal_muscle_relaxation0.87739076
113MP0002108_abnormal_muscle_morphology0.87635904
114MP0008775_abnormal_heart_ventricle0.87508021
115MP0005164_abnormal_response_to0.87233935
116MP0005390_skeleton_phenotype0.86918596
117MP0003634_abnormal_glial_cell0.84611107
118MP0003195_calcinosis0.83884918
119MP0005620_abnormal_muscle_contractility0.83389751
120MP0004883_abnormal_blood_vessel0.83376285
121MP0002735_abnormal_chemical_nociception0.83321208
122MP0003631_nervous_system_phenotype0.81999146
123MP0010155_abnormal_intestine_physiology0.81840534
124MP0005377_hearing/vestibular/ear_phenot0.81768453
125MP0003878_abnormal_ear_physiology0.81768453
126MP0001177_atelectasis0.80666612
127MP0005388_respiratory_system_phenotype0.80471105
128MP0002133_abnormal_respiratory_system0.80471105
129MP0000230_abnormal_systemic_arterial0.79117272
130MP0005165_increased_susceptibility_to0.79067186
131MP0002090_abnormal_vision0.78464688
132MP0008874_decreased_physiological_sensi0.77683727
133MP0009278_abnormal_bone_marrow0.76816431
134MP0001800_abnormal_humoral_immune0.75140450
135MP0002136_abnormal_kidney_physiology0.75066957
136MP0002405_respiratory_system_inflammati0.74669876
137MP0008260_abnormal_autophagy0.74357752
138MP0005248_abnormal_Harderian_gland0.74218869
139MP0001299_abnormal_eye_distance/0.74049847
140MP0004811_abnormal_neuron_physiology0.73622388
141MP0001544_abnormal_cardiovascular_syste0.72696657
142MP0000249_abnormal_blood_vessel0.71573181
143MP0001915_intracranial_hemorrhage0.67421666
144MP0003183_abnormal_peptide_metabolism0.64548420
145MP0001819_abnormal_immune_cell0.64509496
146MP0002420_abnormal_adaptive_immunity0.62955857

Predicted human phenotypes

RankGene SetZ-score
1Disinhibition (HP:0000734)4.06503149
2Nuclear cataract (HP:0100018)3.88019748
3Cerebral aneurysm (HP:0004944)3.24258031
4Increased cerebral lipofuscin (HP:0011813)3.24117876
5Apathy (HP:0000741)3.22780465
6Broad metatarsal (HP:0001783)3.21664978
7Abnormality of macrophages (HP:0004311)3.09175495
8Complement deficiency (HP:0004431)3.05600940
9Diminished motivation (HP:0000745)3.00427107
10Increased circulating renin level (HP:0000848)2.80717770
11Systemic lupus erythematosus (HP:0002725)2.75502327
12Dysostosis multiplex (HP:0000943)2.74430889
13Lymphangioma (HP:0100764)2.73249918
14Hematochezia (HP:0002573)2.72039372
15Focal motor seizures (HP:0011153)2.69114487
16Mucopolysacchariduria (HP:0008155)2.68377087
17Urinary glycosaminoglycan excretion (HP:0003541)2.68377087
18Spontaneous hematomas (HP:0007420)2.66673236
19Orchitis (HP:0100796)2.62757834
20Abnormality of the vasculature of the conjunctiva (HP:0008054)2.61653844
21Abnormality of polysaccharide metabolism (HP:0011012)2.58465963
22Abnormality of glycosaminoglycan metabolism (HP:0004371)2.58465963
23Abnormality of mucopolysaccharide metabolism (HP:0011020)2.58465963
24Recurrent bacterial skin infections (HP:0005406)2.58363885
25Eczematoid dermatitis (HP:0000976)2.56086261
26Metabolic alkalosis (HP:0200114)2.56022172
27Retrobulbar optic neuritis (HP:0100654)2.55685360
28Optic neuritis (HP:0100653)2.55685360
29Myokymia (HP:0002411)2.53330962
30Arterial tortuosity (HP:0005116)2.51451745
31Inappropriate behavior (HP:0000719)2.48271718
32Recurrent gram-negative bacterial infections (HP:0005420)2.47893383
33Vascular tortuosity (HP:0004948)2.47292001
34Focal seizures (HP:0007359)2.46128781
35Protrusio acetabuli (HP:0003179)2.45826421
36Shallow orbits (HP:0000586)2.45591806
37Hypokalemic alkalosis (HP:0001949)2.45496605
38Aortic aneurysm (HP:0004942)2.40895688
39Interstitial pulmonary disease (HP:0006530)2.38569182
40Increased neuronal autofluorescent lipopigment (HP:0002074)2.35596765
41Recurrent abscess formation (HP:0002722)2.33795243
42Abnormality of complement system (HP:0005339)2.32499636
43Amyloidosis (HP:0011034)2.31393438
44Action tremor (HP:0002345)2.30595816
45Axonal loss (HP:0003447)2.29549801
46Mediastinal lymphadenopathy (HP:0100721)2.27702108
47Supranuclear gaze palsy (HP:0000605)2.24194568
48Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.23875782
49Asymmetric septal hypertrophy (HP:0001670)2.22198247
50Premature rupture of membranes (HP:0001788)2.19517537
51Striae distensae (HP:0001065)2.19173827
52Hyperactive renin-angiotensin system (HP:0000841)2.18045291
53Cervical subluxation (HP:0003308)2.15269619
54Agnosia (HP:0010524)2.14251288
55Aortic dissection (HP:0002647)2.12754067
56Dementia (HP:0000726)2.12099893
57Vertebral compression fractures (HP:0002953)2.08083078
58Polyuria (HP:0000103)2.06623561
59Abnormal eating behavior (HP:0100738)2.06499460
60Abnormal urine output (HP:0012590)2.00831989
61Myositis (HP:0100614)2.00184526
62Mitral valve prolapse (HP:0001634)2.00160019
63Dilatation of the ascending aorta (HP:0005111)1.99909477
64Vacuolated lymphocytes (HP:0001922)1.98415412
65Basal ganglia calcification (HP:0002135)1.97930117
66Memory impairment (HP:0002354)1.97796718
67Mitral stenosis (HP:0001718)1.96861774
68Thin bony cortex (HP:0002753)1.96503734
69Hydroxyprolinuria (HP:0003080)1.91185231
70Abnormality of proline metabolism (HP:0010907)1.91185231
71Enlarged penis (HP:0000040)1.89624289
72Overgrowth (HP:0001548)1.88985126
73Progressive neurologic deterioration (HP:0002344)1.87672610
74Abnormality of renal excretion (HP:0011036)1.87415886
75Postural instability (HP:0002172)1.86788498
76Upper motor neuron abnormality (HP:0002127)1.84822052
77Abnormal drinking behavior (HP:0030082)1.84232916
78Polydipsia (HP:0001959)1.84232916
79Aneurysm (HP:0002617)1.83927484
80Pulmonary artery stenosis (HP:0004415)1.83542317
81Neurofibrillary tangles (HP:0002185)1.81513646
82Pulmonary infiltrates (HP:0002113)1.81386479
83Zonular cataract (HP:0010920)1.80935379
84Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.80215217
85Hemiplegia (HP:0002301)1.79695980
86Metaphyseal irregularity (HP:0003025)1.78889597
87Peripheral demyelination (HP:0011096)1.78196930
88Abnormality of glycolipid metabolism (HP:0010969)1.77747575
89Abnormality of liposaccharide metabolism (HP:0010968)1.77747575
90Abnormality of glycosphingolipid metabolism (HP:0004343)1.77747575
91Abnormality of chloride homeostasis (HP:0011422)1.76786654
92Torticollis (HP:0000473)1.76158608
93Tetraparesis (HP:0002273)1.75511895
94Turricephaly (HP:0000262)1.75442757
95Absent frontal sinuses (HP:0002688)1.75032421
96Conjunctival telangiectasia (HP:0000524)1.74711963
97Cerebral inclusion bodies (HP:0100314)1.74446107
98Personality changes (HP:0000751)1.74038332
99Abnormality of the periventricular white matter (HP:0002518)1.73335609
100Spastic tetraparesis (HP:0001285)1.73218759
101Generalized tonic-clonic seizures (HP:0002069)1.73066580
102Rapidly progressive (HP:0003678)1.73031487
103Spondylolisthesis (HP:0003302)1.72289133
104Mutism (HP:0002300)1.71965867
105Bladder diverticulum (HP:0000015)1.70739706
106Distal upper limb amyotrophy (HP:0007149)1.70699157
107Upper limb amyotrophy (HP:0009129)1.70699157
108Pathologic fracture (HP:0002756)1.69820366
109Global brain atrophy (HP:0002283)1.69666819
110Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.69564811
111Glomerulonephritis (HP:0000099)1.69430457
112Esophageal varix (HP:0002040)1.69413562
113Ovoid vertebral bodies (HP:0003300)1.68331992
114Increased CSF protein (HP:0002922)1.66781740
115Hypoplasia of the iris (HP:0007676)1.66539519
116Gingivitis (HP:0000230)1.66432117
117Keratoconjunctivitis sicca (HP:0001097)1.65980154
118Abnormality of renin-angiotensin system (HP:0000847)1.65702918
119Skin nodule (HP:0200036)1.65652126
120Purpura (HP:0000979)1.65581500
121Bone pain (HP:0002653)1.64536599
122Visual hallucinations (HP:0002367)1.64533808
123Hand muscle atrophy (HP:0009130)1.64075009
124Papilledema (HP:0001085)1.63687728
125Nephritis (HP:0000123)1.63532136
126Epileptic encephalopathy (HP:0200134)1.63528087
127Abnormality of the nasal mucosa (HP:0000433)1.63394403
128Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.62592534
129Neuronal loss in central nervous system (HP:0002529)1.61364887
130Hemoptysis (HP:0002105)1.60850262
131Peripheral hypomyelination (HP:0007182)1.60001790
132Macroorchidism (HP:0000053)1.59794398
133Protuberant abdomen (HP:0001538)1.59409683
134Polyphagia (HP:0002591)1.58766004
135Myocardial infarction (HP:0001658)1.58297423
136Impaired social interactions (HP:0000735)1.58170110
137Abnormal social behavior (HP:0012433)1.58170110
138Prolonged neonatal jaundice (HP:0006579)1.57709210
139Abnormality of binocular vision (HP:0011514)1.57158175
140Diplopia (HP:0000651)1.57158175
141Urinary incontinence (HP:0000020)1.56222463
142Ankle contracture (HP:0006466)1.56091396
143Buphthalmos (HP:0000557)1.55801815
144Postural tremor (HP:0002174)1.55666506
145Poor eye contact (HP:0000817)1.54602766
146Follicular hyperkeratosis (HP:0007502)1.53885910
147Hyperaldosteronism (HP:0000859)1.53470872
148Mesangial abnormality (HP:0001966)1.53430796
149Gout (HP:0001997)1.53415017
150J-shaped sella turcica (HP:0002680)1.53222755
151Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.52219219
152Loss of speech (HP:0002371)1.51889911
153Osteopenia (HP:0000938)1.51196004
154Retinal atrophy (HP:0001105)1.50069528
155Polygenic inheritance (HP:0010982)1.49234765
156Autoimmune thrombocytopenia (HP:0001973)1.48790102
157Hypomagnesemia (HP:0002917)1.47800047

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE13.03680585
2IRAK33.02901279
3GRK72.89775557
4EPHA42.68990521
5PRKD32.66861613
6NTRK32.34540775
7TGFBR22.24724132
8RIPK42.23567790
9TRIB32.17556177
10MAP3K142.15144711
11RIPK12.11457182
12BLK2.04426831
13DAPK21.98200443
14MAP3K91.97179655
15PTK2B1.80526362
16CAMK1G1.73080706
17WNK41.70189810
18TAOK21.64511696
19CAMK1D1.62847730
20CAMKK11.61979538
21CDC42BPA1.58839623
22NTRK11.58333562
23EPHA31.58299811
24KSR21.54441715
25ERN11.53905136
26MATK1.50316947
27PDGFRA1.50110222
28MAP3K41.49742321
29PAK61.48126766
30SIK21.42772019
31MINK11.39843009
32KDR1.39706746
33NEK91.39257513
34BMPR21.29312332
35BMX1.29298659
36STK381.29168788
37DMPK1.28555178
38CSK1.28517833
39PRKCH1.28373271
40DDR21.24744970
41JAK11.21327392
42WNK31.18764946
43SIK11.14008962
44IKBKE1.12801627
45SGK31.12309226
46IRAK11.10985045
47LMTK21.10907155
48MAP2K41.10765426
49RET1.08532721
50PKN21.07827580
51FES1.06523114
52MAP3K131.05876679
53IRAK21.03525771
54OXSR11.00951091
55ADRBK20.99962949
56FGFR40.99720913
57PDK20.98845110
58NTRK20.97330486
59PDPK10.96351645
60LATS20.95179500
61ABL20.95066946
62ARAF0.92386267
63PDK10.91741184
64PDK30.91295624
65PDK40.91295624
66PLK20.91105529
67MAP3K20.90734026
68ROCK20.89777059
69KSR10.89523423
70CDK50.89515107
71SGK20.88719161
72FER0.86400927
73MAPK70.84787137
74PIM20.82926062
75SGK2230.82314567
76SGK4940.82314567
77PTK60.82032421
78PRPF4B0.81406227
79IKBKB0.81344259
80CAMKK20.80623129
81MAPK120.78767070
82MAP3K30.75824212
83JAK30.75588651
84WNK10.75114747
85SCYL20.74852566
86GRK50.73510589
87MAP2K70.73282224
88PDGFRB0.72810392
89CAMK10.72809682
90CAMK40.72308301
91TTN0.72069552
92FGFR20.70649224
93MARK10.70517496
94MAP3K110.69760799
95FGFR30.69636646
96DAPK10.67298995
97PKN10.66971643
98SGK10.66662223
99CHUK0.66384112
100CDK60.63851468
101PHKG20.60751560
102PHKG10.60751560
103CDK150.60543216
104MAP3K10.59547928
105EPHB20.59498274
106PRKCG0.59419470
107SIK30.59362263
108INSRR0.59132031
109ACVR1B0.58855958
110MAP3K70.58305578
111ZAP700.57654526
112TYRO30.57474249
113RPS6KA20.57218477
114STK110.56523180
115JAK20.56130163
116MOS0.56080477
117CDK180.55956854
118PRKCE0.54746488
119MAPK40.54022310
120IRAK40.53017510
121TBK10.52123594
122FGR0.52040698
123PRKD10.50959069
124CDK140.50175957
125FYN0.50156741
126TNIK0.50137120
127EPHB10.50066881
128MAP2K10.49886122
129NME20.49668253
130TESK10.49551847
131CDK11A0.48876092
132CAMK2B0.48573885
133CASK0.47735721
134ROCK10.47511122
135TYK20.47044188
136EGFR0.47023455
137MARK20.47012981
138PAK30.46996385
139MAP3K50.46711491
140KIT0.46458201
141SRC0.46222057
142YES10.45815111
143TAOK10.44539273
144PTK20.43933839
145FRK0.43720251
146UHMK10.42595229
147CSF1R0.42169311
148CAMK2G0.40251460
149GSK3A0.38437600
150ABL10.38337533

Predicted pathways (KEGG)

RankGene SetZ-score
1Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.89557578
2Synaptic vesicle cycle_Homo sapiens_hsa047211.76062631
3Asthma_Homo sapiens_hsa053101.72400735
4Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.70680284
5Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.70629744
6Allograft rejection_Homo sapiens_hsa053301.63259565
7Nitrogen metabolism_Homo sapiens_hsa009101.61273121
8Glycosaminoglycan degradation_Homo sapiens_hsa005311.48846705
9Olfactory transduction_Homo sapiens_hsa047401.44959865
10Circadian entrainment_Homo sapiens_hsa047131.42945377
11Gastric acid secretion_Homo sapiens_hsa049711.42752769
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.36893852
13Renin secretion_Homo sapiens_hsa049241.36466260
14Salivary secretion_Homo sapiens_hsa049701.35413913
15Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.35000376
16Long-term potentiation_Homo sapiens_hsa047201.34368606
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.33464490
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.31615013
19Lysosome_Homo sapiens_hsa041421.29307289
20Type II diabetes mellitus_Homo sapiens_hsa049301.28873555
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.28192053
22Graft-versus-host disease_Homo sapiens_hsa053321.27343793
23Morphine addiction_Homo sapiens_hsa050321.25732638
24Type I diabetes mellitus_Homo sapiens_hsa049401.21539050
25Autoimmune thyroid disease_Homo sapiens_hsa053201.21491021
26RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.21013596
27Influenza A_Homo sapiens_hsa051641.19986345
28Collecting duct acid secretion_Homo sapiens_hsa049661.17727893
29Glioma_Homo sapiens_hsa052141.17066553
30Insulin secretion_Homo sapiens_hsa049111.16740915
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.15937451
32GABAergic synapse_Homo sapiens_hsa047271.15915958
33NOD-like receptor signaling pathway_Homo sapiens_hsa046211.15906446
34Glutamatergic synapse_Homo sapiens_hsa047241.12966714
35Amphetamine addiction_Homo sapiens_hsa050311.12732468
36Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.12237488
37Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.11715709
38Nicotine addiction_Homo sapiens_hsa050331.08346354
39Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.07894176
40Complement and coagulation cascades_Homo sapiens_hsa046101.07560596
41Dorso-ventral axis formation_Homo sapiens_hsa043201.07339338
42Dilated cardiomyopathy_Homo sapiens_hsa054141.06021973
43Cholinergic synapse_Homo sapiens_hsa047251.05506620
44Oxytocin signaling pathway_Homo sapiens_hsa049211.04657331
45Legionellosis_Homo sapiens_hsa051341.03647384
46cAMP signaling pathway_Homo sapiens_hsa040241.03356395
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.00019960
48Osteoclast differentiation_Homo sapiens_hsa043800.99829138
49cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96673252
50Amoebiasis_Homo sapiens_hsa051460.95181160
51Tuberculosis_Homo sapiens_hsa051520.93718652
52Focal adhesion_Homo sapiens_hsa045100.93047175
53Hepatitis C_Homo sapiens_hsa051600.92477605
54AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.91949865
55Dopaminergic synapse_Homo sapiens_hsa047280.91719123
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.91402822
57Staphylococcus aureus infection_Homo sapiens_hsa051500.91013191
58Calcium signaling pathway_Homo sapiens_hsa040200.90867687
59Carbohydrate digestion and absorption_Homo sapiens_hsa049730.89739200
60Estrogen signaling pathway_Homo sapiens_hsa049150.89305107
61Sphingolipid metabolism_Homo sapiens_hsa006000.89101965
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.88145648
63GnRH signaling pathway_Homo sapiens_hsa049120.87864258
64Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86286747
65Prolactin signaling pathway_Homo sapiens_hsa049170.85749677
66Vibrio cholerae infection_Homo sapiens_hsa051100.85147358
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.84864457
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83118592
69Bile secretion_Homo sapiens_hsa049760.81844285
70Viral myocarditis_Homo sapiens_hsa054160.80483367
71Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80067123
72Adipocytokine signaling pathway_Homo sapiens_hsa049200.79568586
73Cocaine addiction_Homo sapiens_hsa050300.79407316
74Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.78428986
75ECM-receptor interaction_Homo sapiens_hsa045120.78094945
76Rheumatoid arthritis_Homo sapiens_hsa053230.77750016
77Rap1 signaling pathway_Homo sapiens_hsa040150.77398464
78Gap junction_Homo sapiens_hsa045400.75362569
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.74996871
80Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.74631061
81Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74500880
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.74237239
83Malaria_Homo sapiens_hsa051440.74044495
84Leishmaniasis_Homo sapiens_hsa051400.73464360
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.73104792
86Phagosome_Homo sapiens_hsa041450.73023322
87Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.72655613
88VEGF signaling pathway_Homo sapiens_hsa043700.72260483
89Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.71977702
90Insulin resistance_Homo sapiens_hsa049310.71931374
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71681779
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71677773
93Antigen processing and presentation_Homo sapiens_hsa046120.71395187
94Proteoglycans in cancer_Homo sapiens_hsa052050.71014464
95Vascular smooth muscle contraction_Homo sapiens_hsa042700.70299150
96African trypanosomiasis_Homo sapiens_hsa051430.69856971
97Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.69788057
98PPAR signaling pathway_Homo sapiens_hsa033200.69638601
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.69489949
100Thyroid hormone synthesis_Homo sapiens_hsa049180.69398878
101ErbB signaling pathway_Homo sapiens_hsa040120.69012232
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68937630
103Measles_Homo sapiens_hsa051620.68822260
104Endocytosis_Homo sapiens_hsa041440.68643193
105Pertussis_Homo sapiens_hsa051330.67992075
106Hepatitis B_Homo sapiens_hsa051610.67563114
107Choline metabolism in cancer_Homo sapiens_hsa052310.66639930
108Axon guidance_Homo sapiens_hsa043600.66497902
109Mineral absorption_Homo sapiens_hsa049780.65605538
110Salmonella infection_Homo sapiens_hsa051320.65546291
111Long-term depression_Homo sapiens_hsa047300.65177257
112Prion diseases_Homo sapiens_hsa050200.63407795
113Protein digestion and absorption_Homo sapiens_hsa049740.63249116
114Chemokine signaling pathway_Homo sapiens_hsa040620.60314267
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60003815
116Melanogenesis_Homo sapiens_hsa049160.59997695
117Platelet activation_Homo sapiens_hsa046110.59492186
118B cell receptor signaling pathway_Homo sapiens_hsa046620.59232312
119Shigellosis_Homo sapiens_hsa051310.58908151
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.58391040
121Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.58173602
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58094087
123Toxoplasmosis_Homo sapiens_hsa051450.57269133
124Renal cell carcinoma_Homo sapiens_hsa052110.57090230
125Glucagon signaling pathway_Homo sapiens_hsa049220.55979102
126mTOR signaling pathway_Homo sapiens_hsa041500.55865518
127TNF signaling pathway_Homo sapiens_hsa046680.55255736
128Other glycan degradation_Homo sapiens_hsa005110.55192782
129Bladder cancer_Homo sapiens_hsa052190.54396791
130Leukocyte transendothelial migration_Homo sapiens_hsa046700.49711872
131Herpes simplex infection_Homo sapiens_hsa051680.46860616
132HIF-1 signaling pathway_Homo sapiens_hsa040660.46447553
133Notch signaling pathway_Homo sapiens_hsa043300.46179161
134Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45182370
135Hematopoietic cell lineage_Homo sapiens_hsa046400.42738106
136Ovarian steroidogenesis_Homo sapiens_hsa049130.40475540
137Primary bile acid biosynthesis_Homo sapiens_hsa001200.40153317
138Apoptosis_Homo sapiens_hsa042100.39783232

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