RGL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.93762735
2negative regulation of cell killing (GO:0031342)5.11169054
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.11169054
4regulation of gamma-delta T cell differentiation (GO:0045586)4.88626900
5positive thymic T cell selection (GO:0045059)4.74585613
6regulation of gamma-delta T cell activation (GO:0046643)4.65328572
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.53805384
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.53805384
9positive regulation of B cell differentiation (GO:0045579)4.33205598
10regulation of B cell receptor signaling pathway (GO:0050855)4.20048811
11detection of other organism (GO:0098543)4.14965413
12antigen processing and presentation of endogenous antigen (GO:0019883)4.11975235
13negative regulation of granulocyte differentiation (GO:0030853)4.07884013
14detection of bacterium (GO:0016045)4.06898671
15negative regulation of erythrocyte differentiation (GO:0045647)4.04732526
16regulation of interferon-beta biosynthetic process (GO:0045357)3.96322374
17response to muramyl dipeptide (GO:0032495)3.92173133
18positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.88470467
19modulation by symbiont of host defense response (GO:0052031)3.75135712
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.75135712
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.75135712
22positive regulation by organism of defense response of other organism involved in symbiotic interact3.75135712
23modulation by symbiont of host immune response (GO:0052553)3.75135712
24positive regulation by symbiont of host defense response (GO:0052509)3.75135712
25B cell receptor signaling pathway (GO:0050853)3.72283759
26NIK/NF-kappaB signaling (GO:0038061)3.53412550
27detection of external biotic stimulus (GO:0098581)3.52561980
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.52332883
29negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.48832141
30positive T cell selection (GO:0043368)3.46842331
31regulation of B cell differentiation (GO:0045577)3.45078998
32thymic T cell selection (GO:0045061)3.43930295
33antigen processing and presentation via MHC class Ib (GO:0002475)3.42871548
34macrophage activation involved in immune response (GO:0002281)3.41343314
35regulation of interleukin-12 biosynthetic process (GO:0045075)3.35843816
36regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.35596236
37regulation of mast cell degranulation (GO:0043304)3.29405304
38mannose metabolic process (GO:0006013)3.28903099
39regulation of myeloid leukocyte mediated immunity (GO:0002886)3.25525647
40regulation of leukocyte degranulation (GO:0043300)3.24246662
41immunoglobulin mediated immune response (GO:0016064)3.23748193
42epithelial cell differentiation involved in prostate gland development (GO:0060742)3.23019531
43positive regulation of Cdc42 GTPase activity (GO:0043089)3.22792922
44detection of molecule of bacterial origin (GO:0032490)3.18919774
45positive regulation of histone deacetylation (GO:0031065)3.17452887
46negative regulation of phagocytosis (GO:0050765)3.17114226
47neutrophil mediated immunity (GO:0002446)3.15980688
48detection of biotic stimulus (GO:0009595)3.09449021
49positive regulation of antigen processing and presentation (GO:0002579)3.05453484
50response to peptidoglycan (GO:0032494)3.05079796
51T cell selection (GO:0045058)3.04606380
52pinocytosis (GO:0006907)3.03945810
53negative thymic T cell selection (GO:0045060)3.03935797
54regulation of T-helper 2 cell differentiation (GO:0045628)3.02028744
55leukocyte migration involved in inflammatory response (GO:0002523)2.98945272
56response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.96751810
57response to host immune response (GO:0052572)2.96751810
58negative regulation of stress fiber assembly (GO:0051497)2.96375996
59negative regulation of lymphocyte mediated immunity (GO:0002707)2.91481987
60positive regulation of interferon-alpha production (GO:0032727)2.91252767
61negative T cell selection (GO:0043383)2.90059727
62regulation of mast cell activation involved in immune response (GO:0033006)2.89547135
63interferon-gamma secretion (GO:0072643)2.85432231
64response to laminar fluid shear stress (GO:0034616)2.85247704
65regulation of type I interferon-mediated signaling pathway (GO:0060338)2.84986512
66neutrophil activation involved in immune response (GO:0002283)2.84489835
67defense response to protozoan (GO:0042832)2.83446106
68histone H3-K4 trimethylation (GO:0080182)2.83195723
69regulation of regulated secretory pathway (GO:1903305)2.81496707
70negative regulation of leukocyte mediated immunity (GO:0002704)2.81213740
71macrophage activation (GO:0042116)2.80227081
72negative regulation of interleukin-12 production (GO:0032695)2.78781088
73negative regulation of interleukin-6 production (GO:0032715)2.78634887
74response to type I interferon (GO:0034340)2.78060709
75granulocyte activation (GO:0036230)2.74547501
76germinal center formation (GO:0002467)2.73345961
77cellular response to type I interferon (GO:0071357)2.72235340
78type I interferon signaling pathway (GO:0060337)2.72235340
79regulation of interferon-alpha production (GO:0032647)2.71100790
80regulation of granulocyte differentiation (GO:0030852)2.69450516
81respiratory burst (GO:0045730)2.67461444
82myeloid cell activation involved in immune response (GO:0002275)2.66830427
83peptidyl-tyrosine autophosphorylation (GO:0038083)2.63545837
84positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.63090627
85regulation of erythrocyte differentiation (GO:0045646)2.63030260
86positive regulation of cellular amide metabolic process (GO:0034250)2.62980028
87natural killer cell differentiation (GO:0001779)2.62140026
88cellular extravasation (GO:0045123)2.61926223
89regulation of integrin activation (GO:0033623)2.61750173
90positive regulation of protein deacetylation (GO:0090312)2.61604132
91JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.60585296
92tolerance induction (GO:0002507)2.59103283
93leukocyte aggregation (GO:0070486)2.58470161
94negative regulation of type 2 immune response (GO:0002829)2.58454093
95positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.57677246
96response to protozoan (GO:0001562)2.57417088
97apoptotic cell clearance (GO:0043277)2.56415767
98neutrophil activation (GO:0042119)2.53817950
99negative regulation of innate immune response (GO:0045824)2.53145667
100semaphorin-plexin signaling pathway (GO:0071526)2.52169086
101regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.51252850
102activation of JUN kinase activity (GO:0007257)2.50573915
103cortical actin cytoskeleton organization (GO:0030866)2.50494752
104regulation of ARF protein signal transduction (GO:0032012)2.49963734
105cellular response to zinc ion (GO:0071294)2.47333993
106negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.47017307
107amyloid precursor protein catabolic process (GO:0042987)2.46684398
108positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.46634123
109microglial cell activation (GO:0001774)2.46499468
110negative regulation of glycoprotein biosynthetic process (GO:0010561)2.45851214
111leukocyte cell-cell adhesion (GO:0007159)2.45033332
112lipopolysaccharide-mediated signaling pathway (GO:0031663)2.44884471
113B cell mediated immunity (GO:0019724)2.44285592
114B cell homeostasis (GO:0001782)2.43837937
115response to host (GO:0075136)2.43162809
116response to host defenses (GO:0052200)2.43162809
117response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.43162809
118negative regulation of toll-like receptor signaling pathway (GO:0034122)2.43073736
119regulation of antigen processing and presentation (GO:0002577)2.42449373
120regulation of amyloid precursor protein catabolic process (GO:1902991)2.42444627
121regulation of ARF GTPase activity (GO:0032312)2.40492792
122megakaryocyte development (GO:0035855)2.40252211
123interferon-gamma-mediated signaling pathway (GO:0060333)2.40242319
124myeloid dendritic cell activation (GO:0001773)2.38615196
125positive regulation of regulated secretory pathway (GO:1903307)2.38329920
126antigen receptor-mediated signaling pathway (GO:0050851)2.38054109
127mature B cell differentiation (GO:0002335)2.37843567
128endothelial cell chemotaxis (GO:0035767)2.37740428
129T cell homeostasis (GO:0043029)2.37721154
130positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.37621661
131peptidyl-lysine dimethylation (GO:0018027)2.36582486
132positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.36568879
133response to fluid shear stress (GO:0034405)2.35531864
134regulation of tolerance induction (GO:0002643)2.35522616
135regulation of T cell tolerance induction (GO:0002664)2.35340286
136histone H4 deacetylation (GO:0070933)2.35099094
137I-kappaB phosphorylation (GO:0007252)2.34844872
138positive regulation of lamellipodium organization (GO:1902745)2.34680436
139regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.34558446
140maternal placenta development (GO:0001893)2.33245104
141production of molecular mediator involved in inflammatory response (GO:0002532)2.33191177
142lymphocyte homeostasis (GO:0002260)2.33190475
143regulation of extracellular matrix disassembly (GO:0010715)2.32855987
144regulation of dendritic cell antigen processing and presentation (GO:0002604)2.32830691
145histone H3-K4 methylation (GO:0051568)2.32334423
146negative regulation of bone resorption (GO:0045779)2.32253941
147adaptation of signaling pathway (GO:0023058)2.32218765
1483-UTR-mediated mRNA stabilization (GO:0070935)2.31797330
149regulation of macrophage cytokine production (GO:0010935)2.31469251
150regulation of necroptotic process (GO:0060544)2.29091629

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1VDR_21846776_ChIP-Seq_THP-1_Human3.55054585
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.51218394
3MYC_22102868_ChIP-Seq_BL_Human3.45237726
4E2F7_22180533_ChIP-Seq_HELA_Human3.42932996
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.18386469
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.11863223
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.92561335
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.81492116
9SCL_19346495_ChIP-Seq_HPC-7_Human2.76940978
10IRF8_21731497_ChIP-ChIP_J774_Mouse2.75849808
11TCF7_22412390_ChIP-Seq_EML_Mouse2.68371538
12* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.62237500
13KDM2B_26808549_Chip-Seq_SUP-B15_Human2.38426603
14* VDR_24763502_ChIP-Seq_THP-1_Human2.35501753
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.32881592
16MAF_26560356_Chip-Seq_TH1_Human2.32426578
17ESR2_21235772_ChIP-Seq_MCF-7_Human2.27634701
18* KDM2B_26808549_Chip-Seq_DND41_Human2.26033372
19* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.25913925
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.25626853
21BP1_19119308_ChIP-ChIP_Hs578T_Human2.23152869
22KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.21317116
23ELK3_25401928_ChIP-Seq_HUVEC_Human2.19416757
24E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.18144479
25* SPI1_23127762_ChIP-Seq_K562_Human2.14175402
26UTX_26944678_Chip-Seq_JUKART_Human2.13379491
27BRD4_27068464_Chip-Seq_AML-cells_Mouse2.11304930
28NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.07175744
29RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.02720909
30KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.98207681
31FOXM1_23109430_ChIP-Seq_U2OS_Human1.97756409
32FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.95482710
33SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.92544228
34RUNX1_22412390_ChIP-Seq_EML_Mouse1.91097004
35FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.90409374
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.89512421
37* LXR_22292898_ChIP-Seq_THP-1_Human1.88614135
38ESR1_20079471_ChIP-ChIP_T-47D_Human1.87757829
39TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.86055238
40* SPI1_23547873_ChIP-Seq_NB4_Human1.83742112
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.83621413
42IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.81871457
43MYB_26560356_Chip-Seq_TH2_Human1.74969169
44MYB_26560356_Chip-Seq_TH1_Human1.71666308
45RUNX_20019798_ChIP-Seq_JUKART_Human1.70845100
46TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69475771
47ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.68340400
48IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.64226748
49TP63_17297297_ChIP-ChIP_HaCaT_Human1.63442749
50STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.60564762
51SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59048709
52MAF_26560356_Chip-Seq_TH2_Human1.55959297
53ESR1_21235772_ChIP-Seq_MCF-7_Human1.53403634
54CIITA_25753668_ChIP-Seq_RAJI_Human1.52887802
55RUNX1_27514584_Chip-Seq_MCF-7_Human1.51002104
56MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.49912154
57SA1_27219007_Chip-Seq_ERYTHROID_Human1.49846824
58SMC4_20622854_ChIP-Seq_HELA_Human1.48557510
59STAT4_19710469_ChIP-ChIP_TH1__Mouse1.45742981
60KDM2B_26808549_Chip-Seq_JURKAT_Human1.44118752
61* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.43324560
62TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.39831316
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.36087017
64VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.35604561
65GATA1_22383799_ChIP-Seq_G1ME_Mouse1.34262769
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.34248134
67CREB1_26743006_Chip-Seq_LNCaP_Human1.31768142
68TET1_21451524_ChIP-Seq_MESCs_Mouse1.31240575
69STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.30370958
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.28778953
71* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28482521
72* GATA1_19941827_ChIP-Seq_MEL_Mouse1.28387737
73PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28127209
74TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.28097757
75* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.24773624
76CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.23297755
77UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.22819889
78RACK7_27058665_Chip-Seq_MCF-7_Human1.22798880
79NCOR1_26117541_ChIP-Seq_K562_Human1.22467108
80GATA2_22383799_ChIP-Seq_G1ME_Mouse1.22423241
81* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21444359
82EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.19057120
83* PU_27001747_Chip-Seq_BMDM_Mouse1.18091112
84SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17917269
85PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.17811060
86* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16655631
87Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.16653704
88MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.16130061
89SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.14168835
90* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13404534
91ELF1_20517297_ChIP-Seq_JURKAT_Human1.13168658
92GATA2_21666600_ChIP-Seq_HMVEC_Human1.12584428
93GATA3_27048872_Chip-Seq_THYMUS_Human1.12337338
94LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.11660701
95GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10980008
96SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10656311
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10190002
98RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.08948675
99PU.1_20513432_ChIP-Seq_Bcells_Mouse1.08155438
100GATA1_19941826_ChIP-Seq_K562_Human1.07324814
101BCL6_27268052_Chip-Seq_Bcells_Human1.06954350
102ZNF263_19887448_ChIP-Seq_K562_Human1.06485546
103P68_20966046_ChIP-Seq_HELA_Human1.05222723
104CLOCK_20551151_ChIP-Seq_293T_Human1.04279196
105KDM2B_26808549_Chip-Seq_K562_Human1.04017106
106CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03468731
107TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02757233
108TP63_22573176_ChIP-Seq_HFKS_Human1.02557983
109PPARA_22158963_ChIP-Seq_LIVER_Mouse1.02188488
110CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01330343
111RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.01259232
112BCOR_27268052_Chip-Seq_Bcells_Human1.01252654
113CTCF_26484167_Chip-Seq_Bcells_Mouse1.01181256
114* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01001705
115PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99947557
116RARG_19884340_ChIP-ChIP_MEFs_Mouse0.99441684
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99011026
118SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98835017
119SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98201242
120WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97745961
121ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.97181481
122KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96365315
123* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95763052
124* CTCF_21964334_ChIP-Seq_BJAB-B_Human0.95386330
125P300_27058665_Chip-Seq_ZR-75-30cells_Human0.94853011
126ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94164297
127* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.92672915
128SPI1_20517297_ChIP-Seq_HL60_Human0.92128556
129DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.91584763
130* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90551993
131EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.90210779
132NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89411764
133TP53_22127205_ChIP-Seq_IMR90_Human0.88833878

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.91150884
2MP0003303_peritoneal_inflammation3.16938920
3MP0009278_abnormal_bone_marrow3.10332963
4MP0001835_abnormal_antigen_presentation2.99919779
5MP0005451_abnormal_body_composition2.74428218
6MP0000685_abnormal_immune_system2.73871766
7MP0003172_abnormal_lysosome_physiology2.73340279
8MP0008260_abnormal_autophagy2.71973014
9MP0002396_abnormal_hematopoietic_system2.70865630
10MP0005058_abnormal_lysosome_morphology2.49781599
11MP0005174_abnormal_tail_pigmentation2.43337124
12MP0002166_altered_tumor_susceptibility2.38264404
13MP0001800_abnormal_humoral_immune2.29406560
14MP0003436_decreased_susceptibility_to2.25789838
15MP0004510_myositis2.23139769
16MP0005464_abnormal_platelet_physiology2.21359263
17MP0003300_gastrointestinal_ulcer2.19147627
18MP0001790_abnormal_immune_system2.16936893
19MP0005387_immune_system_phenotype2.16936893
20MP0004381_abnormal_hair_follicle2.14388226
21MP0002452_abnormal_antigen_presenting2.13068590
22MP0004808_abnormal_hematopoietic_stem2.12567615
23MP0002419_abnormal_innate_immunity2.05162404
24MP0001873_stomach_inflammation1.97912424
25MP0005397_hematopoietic_system_phenotyp1.97326065
26MP0001545_abnormal_hematopoietic_system1.97326065
27MP0002420_abnormal_adaptive_immunity1.97004862
28MP0001819_abnormal_immune_cell1.96854288
29MP0005025_abnormal_response_to1.93962594
30MP0002723_abnormal_immune_serum1.91868458
31MP0003763_abnormal_thymus_physiology1.90757687
32MP0002398_abnormal_bone_marrow1.87048724
33MP0005671_abnormal_response_to1.85639352
34MP0005000_abnormal_immune_tolerance1.84288006
35MP0003566_abnormal_cell_adhesion1.80377179
36MP0004858_abnormal_nervous_system1.77611385
37MP0004947_skin_inflammation1.75117452
38MP0004264_abnormal_extraembryonic_tissu1.72476648
39MP0002006_tumorigenesis1.72180104
40MP0000689_abnormal_spleen_morphology1.68990013
41MP0002405_respiratory_system_inflammati1.67120720
42MP0000716_abnormal_immune_system1.64157260
43MP0003705_abnormal_hypodermis_morpholog1.62831667
44MP0002722_abnormal_immune_system1.61280510
45MP0002132_abnormal_respiratory_system1.60001583
46MP0009785_altered_susceptibility_to1.59549078
47MP0005409_darkened_coat_color1.58426376
48MP0000465_gastrointestinal_hemorrhage1.57655426
49MP0005076_abnormal_cell_differentiation1.54257411
50MP0006082_CNS_inflammation1.52596938
51MP0003191_abnormal_cellular_cholesterol1.50459894
52MP0003183_abnormal_peptide_metabolism1.47808561
53MP0005083_abnormal_biliary_tract1.42318767
54MP0002429_abnormal_blood_cell1.41490678
55MP0000703_abnormal_thymus_morphology1.41485209
56MP0000371_diluted_coat_color1.41110717
57MP0010155_abnormal_intestine_physiology1.39844567
58MP0000015_abnormal_ear_pigmentation1.34795852
59MP0008961_abnormal_basal_metabolism1.34506714
60MP0001853_heart_inflammation1.30382573
61MP0002148_abnormal_hypersensitivity_rea1.29775757
62MP0002796_impaired_skin_barrier1.27262916
63MP0010352_gastrointestinal_tract_polyps1.26839040
64MP0001851_eye_inflammation1.26666466
65MP0000858_altered_metastatic_potential1.22126831
66MP0005377_hearing/vestibular/ear_phenot1.20617760
67MP0003878_abnormal_ear_physiology1.20617760
68MP0009333_abnormal_splenocyte_physiolog1.20566321
69MP0005075_abnormal_melanosome_morpholog1.19988323
70MP0003828_pulmonary_edema1.18614350
71MP0001958_emphysema1.17989900
72MP0001845_abnormal_inflammatory_respons1.16520126
73MP0002653_abnormal_ependyma_morphology1.14371512
74MP0005666_abnormal_adipose_tissue1.12254454
75MP0003279_aneurysm1.09642307
76MP0003448_altered_tumor_morphology1.07536604
77MP0010307_abnormal_tumor_latency1.06281853
78MP0001533_abnormal_skeleton_physiology1.06251075
79MP0005375_adipose_tissue_phenotype1.04017368
80MP0005167_abnormal_blood-brain_barrier1.03758778
81MP0005023_abnormal_wound_healing1.03614749
82MP0009840_abnormal_foam_cell1.03573980
83MP0004185_abnormal_adipocyte_glucose1.00023454
84MP0004130_abnormal_muscle_cell0.99703823
85MP0000490_abnormal_crypts_of0.99681549
86MP0000343_altered_response_to0.99194225
87MP0003866_abnormal_defecation0.98183552
88MP0008004_abnormal_stomach_pH0.96729852
89MP0003690_abnormal_glial_cell0.96371842
90MP0003724_increased_susceptibility_to0.95836629
91MP0005390_skeleton_phenotype0.95404304
92MP0004883_abnormal_blood_vessel0.94703745
93MP0000767_abnormal_smooth_muscle0.94550040
94MP0003329_amyloid_beta_deposits0.93232968
95MP0000678_abnormal_parathyroid_gland0.92040613
96MP0002933_joint_inflammation0.90091349
97MP0003453_abnormal_keratinocyte_physiol0.89257792
98MP0003045_fibrosis0.88189761
99MP0008469_abnormal_protein_level0.87664735
100MP0010630_abnormal_cardiac_muscle0.85791384
101MP0005670_abnormal_white_adipose0.85363123
102MP0003091_abnormal_cell_migration0.84810651
103MP0010234_abnormal_vibrissa_follicle0.83792069
104MP0001879_abnormal_lymphatic_vessel0.83386417
105MP0002019_abnormal_tumor_incidence0.81869875
106MP0002254_reproductive_system_inflammat0.79836169
107MP0003075_altered_response_to0.79789264
108MP0000733_abnormal_muscle_development0.79629540
109MP0001915_intracranial_hemorrhage0.79140564
110MP0009931_abnormal_skin_appearance0.78580914
111MP0009384_cardiac_valve_regurgitation0.78091419
112MP0005164_abnormal_response_to0.77400656
113MP0000003_abnormal_adipose_tissue0.75099118
114MP0005310_abnormal_salivary_gland0.74383903
115MP0002998_abnormal_bone_remodeling0.74231585
116MP0000604_amyloidosis0.74207391
117MP0003077_abnormal_cell_cycle0.73562945
118MP0002249_abnormal_larynx_morphology0.72694856
119MP0000249_abnormal_blood_vessel0.72494395
120MP0002075_abnormal_coat/hair_pigmentati0.72453757
121MP0002928_abnormal_bile_duct0.72324730
122MP0001849_ear_inflammation0.71883559
123MP0003795_abnormal_bone_structure0.71474844
124MP0002277_abnormal_respiratory_mucosa0.70578529
125MP0000750_abnormal_muscle_regeneration0.68301148
126MP0010368_abnormal_lymphatic_system0.67736679
127MP0002925_abnormal_cardiovascular_devel0.67447718
128MP0008007_abnormal_cellular_replicative0.66810461
129MP0003111_abnormal_nucleus_morphology0.66063158
130MP0002095_abnormal_skin_pigmentation0.65703293
131MP0000313_abnormal_cell_death0.65331463

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.62125307
2Recurrent bacterial skin infections (HP:0005406)4.24900703
3Abnormality of the fingertips (HP:0001211)3.94226091
4Cerebral aneurysm (HP:0004944)3.89884640
5Eczematoid dermatitis (HP:0000976)3.64217757
6Hematochezia (HP:0002573)3.50108286
7Elevated erythrocyte sedimentation rate (HP:0003565)3.46378740
8Colitis (HP:0002583)3.43312873
9Hyperacusis (HP:0010780)3.39557929
10Abnormality of the nasal mucosa (HP:0000433)3.22229254
11Recurrent fungal infections (HP:0002841)3.19284404
12Gastrointestinal inflammation (HP:0004386)3.12390251
13Inflammation of the large intestine (HP:0002037)3.10034430
14Increased cerebral lipofuscin (HP:0011813)3.08758985
15Recurrent viral infections (HP:0004429)3.00965547
16Cellulitis (HP:0100658)2.99298595
17Obstructive sleep apnea (HP:0002870)2.94953355
18Nasal polyposis (HP:0100582)2.92387176
19Chronic otitis media (HP:0000389)2.92245669
20Optic neuritis (HP:0100653)2.88622639
21Retrobulbar optic neuritis (HP:0100654)2.88622639
22Autoimmune thrombocytopenia (HP:0001973)2.86730044
23Gastrointestinal infarctions (HP:0005244)2.86043557
24Recurrent skin infections (HP:0001581)2.83206244
25Myositis (HP:0100614)2.81355445
26Periodontitis (HP:0000704)2.80910001
27Spontaneous hematomas (HP:0007420)2.80830809
28Amyloidosis (HP:0011034)2.79926852
29Cervical subluxation (HP:0003308)2.79876521
30Pustule (HP:0200039)2.79245782
31Broad face (HP:0000283)2.78544054
32J-shaped sella turcica (HP:0002680)2.71643300
33Metaphyseal cupping (HP:0003021)2.66002734
34Prolonged bleeding time (HP:0003010)2.64771158
35Recurrent cutaneous fungal infections (HP:0011370)2.63007310
36Chronic mucocutaneous candidiasis (HP:0002728)2.63007310
37Abnormal delayed hypersensitivity skin test (HP:0002963)2.53780833
38Abnormality of macrophages (HP:0004311)2.53503382
39Aortic aneurysm (HP:0004942)2.52175694
40Distal lower limb muscle weakness (HP:0009053)2.49375564
41Increased neuronal autofluorescent lipopigment (HP:0002074)2.44052783
42Impaired platelet aggregation (HP:0003540)2.43682284
43Abnormal platelet function (HP:0011869)2.43682284
44Thrombocytosis (HP:0001894)2.43547417
45Mediastinal lymphadenopathy (HP:0100721)2.41483531
46Gingivitis (HP:0000230)2.40283708
47Systemic lupus erythematosus (HP:0002725)2.39273465
48Abnormality of glycolipid metabolism (HP:0010969)2.33659911
49Abnormality of liposaccharide metabolism (HP:0010968)2.33659911
50Abnormality of glycosphingolipid metabolism (HP:0004343)2.33659911
51Dysostosis multiplex (HP:0000943)2.33328380
52Interstitial pulmonary disease (HP:0006530)2.30876532
53Hemorrhage of the eye (HP:0011885)2.30132043
54Thin bony cortex (HP:0002753)2.29997425
55Bicuspid aortic valve (HP:0001647)2.28478163
56Panhypogammaglobulinemia (HP:0003139)2.26618151
57Urethral obstruction (HP:0000796)2.26245853
58Increased IgE level (HP:0003212)2.24813580
59Loss of speech (HP:0002371)2.24249490
60IgM deficiency (HP:0002850)2.21318591
61Flat acetabular roof (HP:0003180)2.17233393
62Increased connective tissue (HP:0009025)2.16989402
63Vacuolated lymphocytes (HP:0001922)2.16948930
64Hypochromic anemia (HP:0001931)2.15401802
65Epistaxis (HP:0000421)2.14725735
66Frequent falls (HP:0002359)2.12701603
67Asymmetric septal hypertrophy (HP:0001670)2.11752766
68Striae distensae (HP:0001065)2.09789387
69Albinism (HP:0001022)2.09384466
70Abnormality of the thoracic spine (HP:0100711)2.08072776
71Osteomyelitis (HP:0002754)2.07531245
72Thoracic kyphosis (HP:0002942)2.07137321
73Meningitis (HP:0001287)2.06797012
74Polygenic inheritance (HP:0010982)2.06119047
75Keratoconjunctivitis sicca (HP:0001097)2.04991338
76Recurrent gram-negative bacterial infections (HP:0005420)2.04386426
77Recurrent bronchitis (HP:0002837)2.02549102
78Urticaria (HP:0001025)1.99955193
79Increased serum ferritin (HP:0003281)1.97949818
80Emphysema (HP:0002097)1.96638643
81Chest pain (HP:0100749)1.96603077
82Spondylolisthesis (HP:0003302)1.96502365
83Peritonitis (HP:0002586)1.96418981
84Agammaglobulinemia (HP:0004432)1.95415488
85Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.95268887
86Purpura (HP:0000979)1.92433971
87Chronic obstructive pulmonary disease (HP:0006510)1.92355706
88Obstructive lung disease (HP:0006536)1.92355706
89Leukocytosis (HP:0001974)1.91089928
90Easy fatigability (HP:0003388)1.91000731
91Verrucae (HP:0200043)1.90705068
92Papilloma (HP:0012740)1.90705068
93Mitral valve prolapse (HP:0001634)1.90252183
94Segmental peripheral demyelination/remyelination (HP:0003481)1.88875730
95Joint stiffness (HP:0001387)1.88364236
96Abnormality of mucopolysaccharide metabolism (HP:0011020)1.87920881
97Abnormality of polysaccharide metabolism (HP:0011012)1.87920881
98Abnormality of glycosaminoglycan metabolism (HP:0004371)1.87920881
99Restrictive lung disease (HP:0002091)1.86689475
100Aneurysm (HP:0002617)1.85960010
101Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.85728831
102Hypertensive crisis (HP:0100735)1.84125828
103Hepatosplenomegaly (HP:0001433)1.83934631
104Disinhibition (HP:0000734)1.83797187
105Keratoconjunctivitis (HP:0001096)1.82319823
106Encephalitis (HP:0002383)1.81838925
107High pitched voice (HP:0001620)1.80822839
108Glomerulonephritis (HP:0000099)1.78957979
109Mucopolysacchariduria (HP:0008155)1.77410645
110Urinary glycosaminoglycan excretion (HP:0003541)1.77410645
111Vasculitis (HP:0002633)1.74515033
112Slow saccadic eye movements (HP:0000514)1.74120314
113Hemoptysis (HP:0002105)1.73707377
114Lymphangioma (HP:0100764)1.73369543
115Growth hormone excess (HP:0000845)1.73289942
116Skin ulcer (HP:0200042)1.73237421
117Ocular albinism (HP:0001107)1.73209830
118Poikiloderma (HP:0001029)1.73055114
119Axonal loss (HP:0003447)1.72998586
120Hypertriglyceridemia (HP:0002155)1.72986674
121Abnormality of the peritoneum (HP:0002585)1.71698111
122Acne (HP:0001061)1.71342202
123Arterial thrombosis (HP:0004420)1.70662402
124Stomatitis (HP:0010280)1.70478146
125Hypercortisolism (HP:0001578)1.70152097
126Pulmonary embolism (HP:0002204)1.70007420
127Abnormality of iron homeostasis (HP:0011031)1.69940313
128Pulmonary infiltrates (HP:0002113)1.69810743
129Bulbar palsy (HP:0001283)1.69616472
130Difficulty climbing stairs (HP:0003551)1.69152279
131Muscle fiber splitting (HP:0003555)1.69130068
132Eosinophilia (HP:0001880)1.68370691
133Intestinal fistula (HP:0100819)1.67958445
134Centrally nucleated skeletal muscle fibers (HP:0003687)1.67864991
135Myopathic facies (HP:0002058)1.67830441
136Large eyes (HP:0001090)1.67759564
137Abnormal vertebral ossification (HP:0100569)1.67658090
138Spinal cord lesions (HP:0100561)1.67075771
139Syringomyelia (HP:0003396)1.67075771
140Bruising susceptibility (HP:0000978)1.66957030
141Increased density of long bones (HP:0006392)1.66880422
142Agnosia (HP:0010524)1.66855966
143Orchitis (HP:0100796)1.66777537
144Elfin facies (HP:0004428)1.65905709
145Deformed sella turcica (HP:0002681)1.65329914
146Long toe (HP:0010511)1.64631900

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.62047150
2TRIB33.09906745
3PKN23.04238497
4TGFBR22.78779482
5KIT2.72033722
6TYK22.67922433
7EEF2K2.59306107
8MAP3K102.54019252
9TTN2.35736368
10TNK22.35276334
11ERN12.32892547
12CSF1R1.90818969
13PRPF4B1.90738788
14JAK31.90000520
15PTK61.87491919
16SIK21.82001786
17SMG11.80895910
18EPHA21.77910854
19CDK121.76163488
20ZAP701.75340457
21MAP2K31.69318734
22TBK11.67541255
23BTK1.55411666
24FGFR41.50767129
25JAK11.48190937
26IKBKE1.46121133
27RIPK41.45523538
28PAK41.43871394
29HCK1.42104512
30BLK1.39773131
31FLT31.39509644
32FES1.38633635
33STK101.36757380
34MAP3K131.36158955
35RIPK11.35367938
36TIE11.29771331
37MAP3K61.28899945
38IRAK41.26417736
39LRRK21.25318841
40EPHB11.23374807
41CAMK1D1.23337289
42SIK31.18733019
43GRK61.17377502
44ICK1.16857640
45FGFR31.14346086
46TESK21.13303413
47ITK1.12681914
48CSK1.12063603
49SYK1.11556474
50MAP3K11.09963926
51TAOK31.09824922
52NEK21.08509189
53CAMK1G1.08186833
54MAP3K141.05684073
55TESK11.04707253
56IRAK31.03299733
57LCK1.00360298
58CDK60.96335289
59JAK20.94632482
60CLK10.92913865
61PDPK10.92712871
62CDC42BPA0.91900610
63MAP3K70.91689291
64KDR0.90427620
65RPS6KA40.88928283
66RET0.88580945
67IKBKB0.84429889
68FGR0.83850346
69MAPKAPK30.81914211
70BRD40.81170140
71HIPK20.78606919
72KSR20.78223062
73MAP2K20.77881909
74TGFBR10.76378192
75TXK0.75764961
76NME20.75552506
77BMX0.73726222
78TEC0.72051219
79CHUK0.71807760
80STK380.71716868
81CDK40.71179819
82MAP2K60.71146908
83MTOR0.68487534
84MAP3K30.66231586
85PIM10.65839712
86PRKCH0.65620397
87RPS6KA60.64646526
88RPS6KA20.64339332
89RPS6KC10.64276521
90RPS6KL10.64276521
91MATK0.64078159
92MAPK120.63015439
93PDGFRA0.61529032
94LYN0.60248561
95IRAK20.58422412
96TAOK10.57935017
97TAOK20.56961330
98PRKD20.56726824
99TRPM70.56677375
100SIK10.56441035
101MAP3K20.56326978
102YES10.56014769
103MAPK110.52967075
104MAPK150.52801677
105RPS6KB20.51882297
106STK40.50872083
107MAP3K110.50507888
108DYRK1B0.50378869
109ALK0.50254159
110PDGFRB0.49805545
111TYRO30.48463579
112MARK30.48308862
113PDK10.46663923
114MAPKAPK20.46381339
115PRKG20.46351438
116MAPK70.46239084
117MAP3K80.45722282
118MARK20.45291585
119CAMKK10.45111095
120FYN0.44882755
121IRAK10.44585079
122SCYL20.44244679
123PAK20.43895833
124PRKD30.43793405
125EGFR0.42815319
126MAP2K40.42457907
127PTK2B0.42399785
128SGK30.40505771
129PRKD10.38775902
130LMTK20.35501596
131CDK90.34735115
132PTK20.34541940

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.49471758
2Osteoclast differentiation_Homo sapiens_hsa043802.25635639
3Leishmaniasis_Homo sapiens_hsa051402.11193690
4Glycosaminoglycan degradation_Homo sapiens_hsa005312.08821216
5Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.05450012
6Primary immunodeficiency_Homo sapiens_hsa053402.00505693
7Other glycan degradation_Homo sapiens_hsa005111.92440164
8Chronic myeloid leukemia_Homo sapiens_hsa052201.83889861
9Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.72623097
10Notch signaling pathway_Homo sapiens_hsa043301.70711025
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.70696208
12Acute myeloid leukemia_Homo sapiens_hsa052211.69745050
13Measles_Homo sapiens_hsa051621.69058338
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.64212163
15Toxoplasmosis_Homo sapiens_hsa051451.60493224
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.55320554
17Staphylococcus aureus infection_Homo sapiens_hsa051501.50433759
18Leukocyte transendothelial migration_Homo sapiens_hsa046701.42697765
19Antigen processing and presentation_Homo sapiens_hsa046121.41713409
20Influenza A_Homo sapiens_hsa051641.39228000
21T cell receptor signaling pathway_Homo sapiens_hsa046601.38590969
22Platelet activation_Homo sapiens_hsa046111.37892187
23Caffeine metabolism_Homo sapiens_hsa002321.37131658
24Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.33813369
25Lysosome_Homo sapiens_hsa041421.33687708
26Herpes simplex infection_Homo sapiens_hsa051681.31580013
27Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.31087342
28Neurotrophin signaling pathway_Homo sapiens_hsa047221.30767311
29Pertussis_Homo sapiens_hsa051331.30535984
30Hematopoietic cell lineage_Homo sapiens_hsa046401.29153885
31AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.28469360
32Tuberculosis_Homo sapiens_hsa051521.26090917
33Apoptosis_Homo sapiens_hsa042101.25470290
34Pancreatic cancer_Homo sapiens_hsa052121.23887271
35VEGF signaling pathway_Homo sapiens_hsa043701.23551760
36Chemokine signaling pathway_Homo sapiens_hsa040621.22425588
37Jak-STAT signaling pathway_Homo sapiens_hsa046301.22226451
38Lysine degradation_Homo sapiens_hsa003101.21652892
39NOD-like receptor signaling pathway_Homo sapiens_hsa046211.19079736
40RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.18442960
41Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.17660459
42Hepatitis B_Homo sapiens_hsa051611.16653672
43Viral myocarditis_Homo sapiens_hsa054161.14950730
44Small cell lung cancer_Homo sapiens_hsa052221.14056584
45Non-small cell lung cancer_Homo sapiens_hsa052231.13088476
46Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11808599
47mTOR signaling pathway_Homo sapiens_hsa041501.11342534
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.10518894
49Shigellosis_Homo sapiens_hsa051311.10103947
50Intestinal immune network for IgA production_Homo sapiens_hsa046721.08344441
51Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.06533096
52TNF signaling pathway_Homo sapiens_hsa046681.03786822
53Colorectal cancer_Homo sapiens_hsa052101.03178437
54GnRH signaling pathway_Homo sapiens_hsa049120.98619853
55Insulin resistance_Homo sapiens_hsa049310.97416971
56Graft-versus-host disease_Homo sapiens_hsa053320.97357126
57ErbB signaling pathway_Homo sapiens_hsa040120.94550004
58Malaria_Homo sapiens_hsa051440.92545864
59Allograft rejection_Homo sapiens_hsa053300.92436837
60HTLV-I infection_Homo sapiens_hsa051660.91975366
61Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91269921
62Autoimmune thyroid disease_Homo sapiens_hsa053200.90465320
63Legionellosis_Homo sapiens_hsa051340.90269291
64Bladder cancer_Homo sapiens_hsa052190.86072285
65Phagosome_Homo sapiens_hsa041450.85734350
66Proteoglycans in cancer_Homo sapiens_hsa052050.85283358
67Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.85225490
68Thyroid cancer_Homo sapiens_hsa052160.84451610
69Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84313254
70Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83106838
71MicroRNAs in cancer_Homo sapiens_hsa052060.82480337
72Hepatitis C_Homo sapiens_hsa051600.80131987
73Prolactin signaling pathway_Homo sapiens_hsa049170.79968616
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79319070
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.79209989
76Salmonella infection_Homo sapiens_hsa051320.79192668
77Focal adhesion_Homo sapiens_hsa045100.78633975
78Type II diabetes mellitus_Homo sapiens_hsa049300.77839704
79HIF-1 signaling pathway_Homo sapiens_hsa040660.77169196
80Adipocytokine signaling pathway_Homo sapiens_hsa049200.76400385
81Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75498650
82Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74586635
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.73614782
84Endometrial cancer_Homo sapiens_hsa052130.73117922
85Prostate cancer_Homo sapiens_hsa052150.70776260
86Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70467959
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68517294
88Insulin signaling pathway_Homo sapiens_hsa049100.66316327
89Glioma_Homo sapiens_hsa052140.66181317
90Central carbon metabolism in cancer_Homo sapiens_hsa052300.65716545
91Amoebiasis_Homo sapiens_hsa051460.65137907
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.65096512
93Epstein-Barr virus infection_Homo sapiens_hsa051690.63683537
94Base excision repair_Homo sapiens_hsa034100.63587788
95Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.63114461
96Viral carcinogenesis_Homo sapiens_hsa052030.62753188
97Fructose and mannose metabolism_Homo sapiens_hsa000510.61993450
98Inositol phosphate metabolism_Homo sapiens_hsa005620.61674425
99Rap1 signaling pathway_Homo sapiens_hsa040150.60579275
100Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.59458478
101Endocytosis_Homo sapiens_hsa041440.59259147
102Pathways in cancer_Homo sapiens_hsa052000.59258719
103Prion diseases_Homo sapiens_hsa050200.59091534
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59049625
105AMPK signaling pathway_Homo sapiens_hsa041520.56764189
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.56612748
107ABC transporters_Homo sapiens_hsa020100.56574907
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56016432
109Renal cell carcinoma_Homo sapiens_hsa052110.54618094
110Dorso-ventral axis formation_Homo sapiens_hsa043200.53914393
111Estrogen signaling pathway_Homo sapiens_hsa049150.53904901
112Pentose phosphate pathway_Homo sapiens_hsa000300.53559692
113Choline metabolism in cancer_Homo sapiens_hsa052310.53058705
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50876201
115DNA replication_Homo sapiens_hsa030300.50567813
116MAPK signaling pathway_Homo sapiens_hsa040100.50297720
117Adherens junction_Homo sapiens_hsa045200.48033930
118FoxO signaling pathway_Homo sapiens_hsa040680.46069990
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43873467

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