RGMB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.37819532
2pyrimidine nucleobase catabolic process (GO:0006208)4.98465690
3cell migration in hindbrain (GO:0021535)4.81876536
4axonal fasciculation (GO:0007413)4.70805919
5presynaptic membrane organization (GO:0097090)4.59944431
6neuron recognition (GO:0008038)4.45524373
7dendritic spine morphogenesis (GO:0060997)4.36071132
8layer formation in cerebral cortex (GO:0021819)4.20058212
9protein heterotrimerization (GO:0070208)4.07455850
10neuron cell-cell adhesion (GO:0007158)3.99021163
11nucleobase catabolic process (GO:0046113)3.91080075
12vocalization behavior (GO:0071625)3.90748845
13positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.85850153
14sequestering of extracellular ligand from receptor (GO:0035581)3.78303455
15substrate-independent telencephalic tangential migration (GO:0021826)3.77669761
16substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.77669761
17cerebellar Purkinje cell differentiation (GO:0021702)3.76040944
18synaptic vesicle maturation (GO:0016188)3.74693449
19regulation of short-term neuronal synaptic plasticity (GO:0048172)3.61455793
20central nervous system projection neuron axonogenesis (GO:0021952)3.60138325
21negative regulation of axon guidance (GO:1902668)3.58430585
22mating behavior (GO:0007617)3.55891625
23negative regulation of axon extension involved in axon guidance (GO:0048843)3.49643004
24protein localization to synapse (GO:0035418)3.46220705
25dendrite morphogenesis (GO:0048813)3.45467111
26axon extension (GO:0048675)3.45268742
27establishment of mitochondrion localization (GO:0051654)3.45223337
28retinal ganglion cell axon guidance (GO:0031290)3.41372905
29negative regulation of microtubule polymerization (GO:0031115)3.40654219
30regulation of synapse structural plasticity (GO:0051823)3.40153540
31glutamate secretion (GO:0014047)3.37007339
32positive regulation of gastrulation (GO:2000543)3.35320641
33regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.35007693
34kidney mesenchyme development (GO:0072074)3.28387379
35collagen fibril organization (GO:0030199)3.24105608
36synaptic vesicle exocytosis (GO:0016079)3.23682021
37exploration behavior (GO:0035640)3.20153856
38neurofilament cytoskeleton organization (GO:0060052)3.12555389
39regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.12287351
40regulation of axon guidance (GO:1902667)3.10682470
41ganglion development (GO:0061548)3.10284943
42establishment of nucleus localization (GO:0040023)3.09744054
43presynaptic membrane assembly (GO:0097105)3.09026497
44neuron projection extension (GO:1990138)3.06376562
45type B pancreatic cell proliferation (GO:0044342)3.05177861
46proline transport (GO:0015824)3.04437701
47response to auditory stimulus (GO:0010996)3.02264410
48metanephric mesenchyme development (GO:0072075)2.99518404
49regulation of glutamate receptor signaling pathway (GO:1900449)2.99379333
50regulation of axon extension involved in axon guidance (GO:0048841)2.99043506
51positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.97807977
52desmosome organization (GO:0002934)2.94502309
53negative regulation of catenin import into nucleus (GO:0035414)2.94289034
54regulation of synaptic vesicle exocytosis (GO:2000300)2.94055353
55positive regulation of filopodium assembly (GO:0051491)2.94001451
56lens morphogenesis in camera-type eye (GO:0002089)2.93812265
57hippocampus development (GO:0021766)2.92890456
58innervation (GO:0060384)2.90662924
59auditory behavior (GO:0031223)2.90259240
60negative regulation of axon extension (GO:0030517)2.90121159
61positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.89660971
62regulation of axon extension (GO:0030516)2.88897955
63regulation of neuronal synaptic plasticity (GO:0048168)2.88073486
64regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.87290549
65regulation of synaptic vesicle transport (GO:1902803)2.86961401
66calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.85872291
67positive regulation of axon extension (GO:0045773)2.85023065
68positive regulation of synapse assembly (GO:0051965)2.84232421
69locomotory exploration behavior (GO:0035641)2.82986349
70dendritic spine organization (GO:0097061)2.82573221
71central nervous system neuron axonogenesis (GO:0021955)2.81890142
72skin morphogenesis (GO:0043589)2.81275630
73regulation of NFAT protein import into nucleus (GO:0051532)2.79784642
74postsynaptic membrane organization (GO:0001941)2.79215256
75neuronal action potential propagation (GO:0019227)2.78666229
76establishment of tissue polarity (GO:0007164)2.77497658
77establishment of planar polarity (GO:0001736)2.77497658
78urinary tract smooth muscle contraction (GO:0014848)2.76873333
79mitochondrion transport along microtubule (GO:0047497)2.76057010
80establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.76057010
81positive regulation of synaptic transmission, GABAergic (GO:0032230)2.75547222
82regulation of synapse assembly (GO:0051963)2.75023034
83positive regulation of mitochondrial fission (GO:0090141)2.74166237
84cell migration involved in sprouting angiogenesis (GO:0002042)2.73377241
85bone trabecula formation (GO:0060346)2.73344972
86cell communication involved in cardiac conduction (GO:0086065)2.73261031
87negative regulation of dendrite development (GO:2000171)2.72931372
88chondrocyte proliferation (GO:0035988)2.72687438
89synaptic vesicle endocytosis (GO:0048488)2.71294143
90paraxial mesoderm development (GO:0048339)2.70918852
91neuron migration (GO:0001764)2.68739910
92regulation of extent of cell growth (GO:0061387)2.67703445
93synaptic vesicle docking involved in exocytosis (GO:0016081)2.65304870
94regulation of long-term neuronal synaptic plasticity (GO:0048169)2.63039230
95embryonic body morphogenesis (GO:0010172)2.62362564
96cerebellum development (GO:0021549)2.61538734
97neuronal ion channel clustering (GO:0045161)2.61504660
98negative regulation of synaptic transmission, GABAergic (GO:0032229)2.61313228
99organelle transport along microtubule (GO:0072384)2.61244755
100G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.61180226
101positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.60241018
102substrate-dependent cell migration (GO:0006929)2.59858857
103negative regulation of axonogenesis (GO:0050771)2.59165651
104spinal cord development (GO:0021510)2.58835191
105membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.58707175
106positive regulation of synapse maturation (GO:0090129)2.57693390
107cranial nerve morphogenesis (GO:0021602)2.57630165
108neuromuscular synaptic transmission (GO:0007274)2.57199689
109negative chemotaxis (GO:0050919)2.56490358
110suckling behavior (GO:0001967)2.56438904
111synapse assembly (GO:0007416)2.56412151
112regulation of cAMP-dependent protein kinase activity (GO:2000479)2.55943179
113membrane depolarization during action potential (GO:0086010)2.55422001
114homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.55208042
115cochlea morphogenesis (GO:0090103)2.54763989
116endocardial cushion development (GO:0003197)2.53854172
117regulation of axonogenesis (GO:0050770)2.53210967
118regulation of synapse organization (GO:0050807)2.51397467
119positive regulation of axonogenesis (GO:0050772)2.51231837
120actin filament depolymerization (GO:0030042)2.49548419
121planar cell polarity pathway involved in neural tube closure (GO:0090179)2.47997767
122regulation of respiratory system process (GO:0044065)2.46257731
123urogenital system development (GO:0001655)2.45668280
124forebrain neuron differentiation (GO:0021879)2.45457863
125neuron projection morphogenesis (GO:0048812)2.45014167
126regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.44542582
127camera-type eye morphogenesis (GO:0048593)2.44367605
128regulation of neuron migration (GO:2001222)2.44354552
129protein retention in ER lumen (GO:0006621)2.43529026
130neurotransmitter secretion (GO:0007269)2.43501871
131regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.43225327
132detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.43135421
133detection of temperature stimulus involved in sensory perception (GO:0050961)2.43135421
134negative regulation of organelle assembly (GO:1902116)2.43024478
135neuronal action potential (GO:0019228)2.42805305
136neuron projection extension involved in neuron projection guidance (GO:1902284)2.42682548
137axon extension involved in axon guidance (GO:0048846)2.42682548
138body morphogenesis (GO:0010171)2.42470687
139developmental cell growth (GO:0048588)2.42099541
140dendrite development (GO:0016358)2.40238016
141regulation of chromatin binding (GO:0035561)2.38138675
142cerebral cortex radially oriented cell migration (GO:0021799)2.38047687
143cellular response to prostaglandin stimulus (GO:0071379)2.37533972
144regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.35121827
145peristalsis (GO:0030432)2.35030086
146ionotropic glutamate receptor signaling pathway (GO:0035235)2.33282141
147cerebellar Purkinje cell layer development (GO:0021680)2.33173379
148endodermal cell differentiation (GO:0035987)2.32347344

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.72898491
2EZH2_27304074_Chip-Seq_ESCs_Mouse3.11795868
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.91869073
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91782949
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.85971556
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.80946277
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.80946277
8* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.77719687
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.70254241
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.64046508
11* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55746082
12GBX2_23144817_ChIP-Seq_PC3_Human2.53382951
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50177970
14* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.47684098
15* EZH2_27294783_Chip-Seq_ESCs_Mouse2.40546171
16RNF2_27304074_Chip-Seq_ESCs_Mouse2.38449220
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.34074226
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.28938077
19* WT1_19549856_ChIP-ChIP_CCG9911_Human2.27356279
20BMI1_23680149_ChIP-Seq_NPCS_Mouse2.13595767
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.12578848
22PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.09673920
23TP63_17297297_ChIP-ChIP_HaCaT_Human2.05020268
24REST_21632747_ChIP-Seq_MESCs_Mouse1.99704491
25PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.99508411
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.93304344
27AR_21572438_ChIP-Seq_LNCaP_Human1.81129048
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.78996314
29RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.76354015
30DROSHA_22980978_ChIP-Seq_HELA_Human1.72422896
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69774800
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.67251369
33RNF2_27304074_Chip-Seq_NSC_Mouse1.66697657
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.65499559
35RING1B_27294783_Chip-Seq_NPCs_Mouse1.62956299
36* REST_18959480_ChIP-ChIP_MESCs_Mouse1.62872787
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.59590992
38* RING1B_27294783_Chip-Seq_ESCs_Mouse1.56787262
39IGF1R_20145208_ChIP-Seq_DFB_Human1.56090844
40ERG_21242973_ChIP-ChIP_JURKAT_Human1.55733586
41TP53_20018659_ChIP-ChIP_R1E_Mouse1.52820078
42RARG_19884340_ChIP-ChIP_MEFs_Mouse1.50848376
43ZFP281_18757296_ChIP-ChIP_E14_Mouse1.48436531
44KDM2B_26808549_Chip-Seq_K562_Human1.48020096
45RARB_27405468_Chip-Seq_BRAIN_Mouse1.40458514
46* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.40448152
47WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.39771702
48* BRD4_25478319_ChIP-Seq_HGPS_Human1.38959711
49ZNF274_21170338_ChIP-Seq_K562_Hela1.38825984
50* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37095031
51STAT6_21828071_ChIP-Seq_BEAS2B_Human1.36886584
52HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.36675595
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.32917621
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32378122
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.32144637
56AHR_22903824_ChIP-Seq_MCF-7_Human1.31977071
57TRIM28_21343339_ChIP-Seq_HEK293_Human1.26711593
58* CJUN_26792858_Chip-Seq_BT549_Human1.25932049
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.24685916
60ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.24090087
61ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23698534
62TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23490960
63TAF15_26573619_Chip-Seq_HEK293_Human1.22646416
64* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.21285398
65* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.21104299
66* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.21104299
67SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20408212
68TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.19127003
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.16724937
70DNAJC2_21179169_ChIP-ChIP_NT2_Human1.14330050
71ESR2_21235772_ChIP-Seq_MCF-7_Human1.12386383
72TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.12198041
73SOX2_21211035_ChIP-Seq_LN229_Gbm1.09484617
74SMAD_19615063_ChIP-ChIP_OVARY_Human1.09419619
75* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.08259720
76* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.07914131
77KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.06781274
78* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.06476267
79VDR_22108803_ChIP-Seq_LS180_Human1.06390328
80CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05918298
81GATA1_26923725_Chip-Seq_HPCs_Mouse1.04775310
82SMAD4_21799915_ChIP-Seq_A2780_Human1.04739182
83* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.03839491
84SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.02965648
85* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.02184735
86* AR_19668381_ChIP-Seq_PC3_Human1.01619458
87* P300_19829295_ChIP-Seq_ESCs_Human1.01178453
88TBX3_20139965_ChIP-Seq_MESCs_Mouse1.00743562
89ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00625933
90TBX3_20139965_ChIP-Seq_ESCs_Mouse1.00339456
91ZNF263_19887448_ChIP-Seq_K562_Human0.99256215
92P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99175571
93RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99024575
94CTCF_27219007_Chip-Seq_Bcells_Human0.98742487
95RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98566946
96MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98028947
97SMAD3_21741376_ChIP-Seq_ESCs_Human0.96440436
98TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.96392761
99EP300_21415370_ChIP-Seq_HL-1_Mouse0.96284208
100POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96111097
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96111097
102ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95761870
103ISL1_27105846_Chip-Seq_CPCs_Mouse0.95753932
104* SMAD3_21741376_ChIP-Seq_EPCs_Human0.95685756
105SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.95034486
106CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94764501
107* SMAD4_21741376_ChIP-Seq_HESCs_Human0.94691013
108OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94155819
109EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.92306533
110LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91742331
111THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91511635
112CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90931163
113AR_25329375_ChIP-Seq_VCAP_Human0.90340732
114TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.89279647
115* SOX9_26525672_Chip-Seq_HEART_Mouse0.89120129
116SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.88861206
117CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.88643600
118TP53_18474530_ChIP-ChIP_U2OS_Human0.88636242
119* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88545390
120TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88384252
121TP53_16413492_ChIP-PET_HCT116_Human0.87984842
122HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.87746098
123TP53_22127205_ChIP-Seq_IMR90_Human0.87159956
124MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87021061
125ELK4_26923725_Chip-Seq_MESODERM_Mouse0.86843269
126PIAS1_25552417_ChIP-Seq_VCAP_Human0.84905554
127* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.84057472
128SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.84001276
129TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.83206107
130TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.81761766

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen4.09795963
2MP0004859_abnormal_synaptic_plasticity3.95131547
3MP0003122_maternal_imprinting3.37088858
4MP0004270_analgesia3.27722092
5MP0006276_abnormal_autonomic_nervous3.23426158
6MP0001968_abnormal_touch/_nociception3.06957327
7MP0000778_abnormal_nervous_system2.97612120
8MP0002735_abnormal_chemical_nociception2.95965013
9MP0005503_abnormal_tendon_morphology2.83793553
10MP0001542_abnormal_bone_strength2.71537415
11MP0003880_abnormal_central_pattern2.64655089
12MP0004858_abnormal_nervous_system2.52793683
13MP0002736_abnormal_nociception_after2.51530575
14MP0003635_abnormal_synaptic_transmissio2.45939478
15MP0002733_abnormal_thermal_nociception2.45039473
16MP0002734_abnormal_mechanical_nocicepti2.35300545
17MP0005645_abnormal_hypothalamus_physiol2.34494448
18MP0003705_abnormal_hypodermis_morpholog2.34060316
19MP0002184_abnormal_innervation2.27501924
20MP0002063_abnormal_learning/memory/cond2.23513735
21MP0001958_emphysema2.23283329
22MP0002653_abnormal_ependyma_morphology2.12142451
23MP0004272_abnormal_basement_membrane2.11649296
24MP0001970_abnormal_pain_threshold2.03661443
25MP0005423_abnormal_somatic_nervous2.02457879
26MP0003279_aneurysm2.00776770
27MP0009384_cardiac_valve_regurgitation1.91006350
28MP0008961_abnormal_basal_metabolism1.87706594
29MP0000569_abnormal_digit_pigmentation1.81550263
30MP0001529_abnormal_vocalization1.79381689
31MP0001188_hyperpigmentation1.66898301
32MP0004811_abnormal_neuron_physiology1.65896921
33MP0002572_abnormal_emotion/affect_behav1.64283256
34MP0010030_abnormal_orbit_morphology1.64117740
35MP0002557_abnormal_social/conspecific_i1.61684000
36MP0010386_abnormal_urinary_bladder1.60594323
37MP0000955_abnormal_spinal_cord1.58904047
38MP0002751_abnormal_autonomic_nervous1.58610810
39MP0000538_abnormal_urinary_bladder1.57497733
40MP0003121_genomic_imprinting1.55255417
41MP0001440_abnormal_grooming_behavior1.54662863
42MP0009745_abnormal_behavioral_response1.53997935
43MP0001984_abnormal_olfaction1.50047331
44MP0002064_seizures1.48567386
45MP0008995_early_reproductive_senescence1.40275759
46MP0003283_abnormal_digestive_organ1.40048259
47MP0002067_abnormal_sensory_capabilities1.39836278
48MP0002102_abnormal_ear_morphology1.38063898
49MP0010368_abnormal_lymphatic_system1.38026493
50MP0009046_muscle_twitch1.36570945
51MP0002882_abnormal_neuron_morphology1.35595047
52MP0002272_abnormal_nervous_system1.31749744
53MP0009250_abnormal_appendicular_skeleto1.31214191
54MP0000751_myopathy1.30339740
55MP0001486_abnormal_startle_reflex1.28297274
56MP0004885_abnormal_endolymph1.25523610
57MP0005499_abnormal_olfactory_system1.24999587
58MP0005394_taste/olfaction_phenotype1.24999587
59MP0008789_abnormal_olfactory_epithelium1.24049481
60MP0000534_abnormal_ureter_morphology1.22682620
61MP0005275_abnormal_skin_tensile1.20105673
62MP0003137_abnormal_impulse_conducting1.19107068
63MP0005508_abnormal_skeleton_morphology1.18016455
64MP0002822_catalepsy1.17250437
65MP0002638_abnormal_pupillary_reflex1.16940708
66MP0001348_abnormal_lacrimal_gland1.16317266
67MP0000537_abnormal_urethra_morphology1.13721143
68MP0003890_abnormal_embryonic-extraembry1.11066735
69MP0003385_abnormal_body_wall1.09826468
70MP0003861_abnormal_nervous_system1.07360365
71MP0002152_abnormal_brain_morphology1.07215054
72MP0003942_abnormal_urinary_system1.06768248
73MP0008569_lethality_at_weaning1.06281255
74MP0001299_abnormal_eye_distance/1.06111624
75MP0004145_abnormal_muscle_electrophysio1.05042995
76MP0005646_abnormal_pituitary_gland1.04436907
77MP0002896_abnormal_bone_mineralization1.03669895
78MP0009780_abnormal_chondrocyte_physiolo1.03020624
79MP0003091_abnormal_cell_migration1.02733033
80MP0009053_abnormal_anal_canal1.02680220
81MP0002909_abnormal_adrenal_gland1.02261738
82MP0000049_abnormal_middle_ear0.99111591
83MP0003787_abnormal_imprinting0.98831081
84MP0004134_abnormal_chest_morphology0.98619221
85MP0003119_abnormal_digestive_system0.98497420
86MP0002066_abnormal_motor_capabilities/c0.98039401
87MP0005386_behavior/neurological_phenoty0.97802427
88MP0004924_abnormal_behavior0.97802427
89MP0002108_abnormal_muscle_morphology0.95571441
90MP0000631_abnormal_neuroendocrine_gland0.95243270
91MP0002752_abnormal_somatic_nervous0.94830188
92MP0002234_abnormal_pharynx_morphology0.94542654
93MP0002796_impaired_skin_barrier0.93053656
94MP0000566_synostosis0.93052119
95MP0002233_abnormal_nose_morphology0.92664220
96MP0000462_abnormal_digestive_system0.92360307
97MP0000003_abnormal_adipose_tissue0.89738038
98MP0001502_abnormal_circadian_rhythm0.88809336
99MP0006054_spinal_hemorrhage0.87870758
100MP0002295_abnormal_pulmonary_circulatio0.87536517
101MP0005076_abnormal_cell_differentiation0.87474661
102MP0003950_abnormal_plasma_membrane0.86962323
103MP0003938_abnormal_ear_development0.86933703
104MP0001879_abnormal_lymphatic_vessel0.84933341
105MP0000749_muscle_degeneration0.84924932
106MP0002160_abnormal_reproductive_system0.84841556
107MP0005595_abnormal_vascular_smooth0.84735668
108MP0003937_abnormal_limbs/digits/tail_de0.83528545
109MP0000013_abnormal_adipose_tissue0.82451574
110MP0002282_abnormal_trachea_morphology0.81733109
111MP0000733_abnormal_muscle_development0.81418691
112MP0005187_abnormal_penis_morphology0.80493404
113MP0000767_abnormal_smooth_muscle0.79996202
114MP0000026_abnormal_inner_ear0.79703941
115MP0001501_abnormal_sleep_pattern0.79589015
116MP0002081_perinatal_lethality0.77886335
117MP0003315_abnormal_perineum_morphology0.77486981
118MP0002069_abnormal_eating/drinking_beha0.76798280
119MP0001340_abnormal_eyelid_morphology0.76760508
120MP0002116_abnormal_craniofacial_bone0.76632521
121MP0003941_abnormal_skin_development0.75485928
122MP0000750_abnormal_muscle_regeneration0.74794925
123MP0003755_abnormal_palate_morphology0.74619404
124MP0003935_abnormal_craniofacial_develop0.74164628
125MP0001270_distended_abdomen0.74133551
126MP0004142_abnormal_muscle_tone0.74127612
127MP0003115_abnormal_respiratory_system0.73990150
128MP0004233_abnormal_muscle_weight0.73771249
129MP0002177_abnormal_outer_ear0.72629049
130MP0001346_abnormal_lacrimal_gland0.70078726
131MP0001943_abnormal_respiration0.69976935
132MP0004085_abnormal_heartbeat0.69251111
133MP0003329_amyloid_beta_deposits0.68332113
134MP0005623_abnormal_meninges_morphology0.68230609
135MP0003959_abnormal_lean_body0.67478258
136MP0010234_abnormal_vibrissa_follicle0.67218706
137MP0001664_abnormal_digestion0.67049832
138MP0005257_abnormal_intraocular_pressure0.66981145

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.52569055
2Protrusio acetabuli (HP:0003179)5.08182321
3Failure to thrive in infancy (HP:0001531)4.64483240
4Myokymia (HP:0002411)3.94954890
5Polyphagia (HP:0002591)3.88686141
6Ankle contracture (HP:0006466)3.75377994
7Abnormality of dentin (HP:0010299)3.66244763
8Type 1 muscle fiber predominance (HP:0003803)3.52796304
9Atrophic scars (HP:0001075)3.52405983
10Soft skin (HP:0000977)3.50524526
11Bladder diverticulum (HP:0000015)3.47097119
12Sleep apnea (HP:0010535)3.46101939
13Vascular tortuosity (HP:0004948)3.37170181
14Aortic dissection (HP:0002647)3.33860865
15Neonatal short-limb short stature (HP:0008921)3.30530505
16Follicular hyperkeratosis (HP:0007502)3.29718138
17Agitation (HP:0000713)3.28637122
18Ankle clonus (HP:0011448)3.21581403
19Ulnar claw (HP:0001178)3.13856776
20Abnormal eating behavior (HP:0100738)3.05543957
21Supranuclear gaze palsy (HP:0000605)2.99138191
22Focal seizures (HP:0007359)2.99113117
23Focal motor seizures (HP:0011153)2.98728303
24Genu recurvatum (HP:0002816)2.97016212
25Spinal rigidity (HP:0003306)2.96897259
26Exotropia (HP:0000577)2.96702730
27Bowel diverticulosis (HP:0005222)2.93766509
28Hypoventilation (HP:0002791)2.93201809
29Aortic aneurysm (HP:0004942)2.89486085
30Arterial tortuosity (HP:0005116)2.86359364
31Overgrowth (HP:0001548)2.84479947
32Action tremor (HP:0002345)2.83839924
33Hypoplasia of the brainstem (HP:0002365)2.80518298
34Aplasia/Hypoplasia of the brainstem (HP:0007362)2.80518298
35Limb dystonia (HP:0002451)2.79818133
36Progressive cerebellar ataxia (HP:0002073)2.78444822
37Hand muscle atrophy (HP:0009130)2.73224287
38Broad metatarsal (HP:0001783)2.65401334
39Abnormality of the lower motor neuron (HP:0002366)2.64004266
40Shallow orbits (HP:0000586)2.62669117
41Slender build (HP:0001533)2.62461634
42Insidious onset (HP:0003587)2.58472844
43Termporal pattern (HP:0011008)2.58472844
44Ventricular fibrillation (HP:0001663)2.57681845
45Wrist flexion contracture (HP:0001239)2.55578466
46Distal upper limb amyotrophy (HP:0007149)2.52444638
47Upper limb amyotrophy (HP:0009129)2.52444638
48Mildly elevated creatine phosphokinase (HP:0008180)2.52326175
49Narrow nasal bridge (HP:0000446)2.51536044
50Ankyloglossia (HP:0010296)2.46261716
51Wormian bones (HP:0002645)2.44957023
52Amblyopia (HP:0000646)2.43915253
53Esotropia (HP:0000565)2.43749436
54Epileptic encephalopathy (HP:0200134)2.35076586
55Limb-girdle muscle weakness (HP:0003325)2.33350587
56Obstructive sleep apnea (HP:0002870)2.32543850
57Mutism (HP:0002300)2.32202547
58Atonic seizures (HP:0010819)2.31660800
59Mitral regurgitation (HP:0001653)2.25762246
60Lissencephaly (HP:0001339)2.24523214
61Shoulder girdle muscle weakness (HP:0003547)2.23221879
62Fragile skin (HP:0001030)2.22241014
63Mild short stature (HP:0003502)2.20727763
64Megalencephaly (HP:0001355)2.20406528
65Wide anterior fontanel (HP:0000260)2.19404933
66Genetic anticipation (HP:0003743)2.15705868
67Papilledema (HP:0001085)2.15232125
68Hyperextensible skin (HP:0000974)2.14552728
69Febrile seizures (HP:0002373)2.13980925
70Insomnia (HP:0100785)2.13832310
71Visual hallucinations (HP:0002367)2.12795534
72Excessive salivation (HP:0003781)2.10930664
73Drooling (HP:0002307)2.10930664
74Aortic regurgitation (HP:0001659)2.10732454
75Abnormality of the labia minora (HP:0012880)2.09669431
76Renal duplication (HP:0000075)2.09452547
77Cutaneous finger syndactyly (HP:0010554)2.09341830
78Labial hypoplasia (HP:0000066)2.06669443
79Specific learning disability (HP:0001328)2.06225189
80Deviation of the hallux (HP:0010051)2.04891517
81Peritonitis (HP:0002586)2.04144233
82Delayed gross motor development (HP:0002194)2.02664287
83Hallux valgus (HP:0001822)2.02138587
84Urinary urgency (HP:0000012)2.00920389
85Calcaneovalgus deformity (HP:0001848)1.99287302
86Mitral valve prolapse (HP:0001634)1.98804183
87Abnormal hair whorl (HP:0010721)1.98643438
88Abnormality of the aortic arch (HP:0012303)1.96531577
89Abnormality of the corticospinal tract (HP:0002492)1.95062581
90Hypercortisolism (HP:0001578)1.94932993
91Bradycardia (HP:0001662)1.94882191
92Deformed tarsal bones (HP:0008119)1.94827506
93Long toe (HP:0010511)1.94139616
94Joint laxity (HP:0001388)1.93421167
95Infantile muscular hypotonia (HP:0008947)1.92587194
96Increased variability in muscle fiber diameter (HP:0003557)1.92486423
97Abnormal EKG (HP:0003115)1.92313958
98Hyperacusis (HP:0010780)1.91774969
99Deep palmar crease (HP:0006191)1.91198870
100Akinesia (HP:0002304)1.89992611
101Hammertoe (HP:0001765)1.89605766
102Lower limb muscle weakness (HP:0007340)1.88549408
103Fetal akinesia sequence (HP:0001989)1.88154985
104Truncal ataxia (HP:0002078)1.87117645
105Aqueductal stenosis (HP:0002410)1.86182280
106Absence seizures (HP:0002121)1.84833973
107Broad-based gait (HP:0002136)1.83563606
108Torticollis (HP:0000473)1.83419696
109Neoplasm of the heart (HP:0100544)1.82425350
110Hypoplastic female external genitalia (HP:0012815)1.81797814
111Biconcave vertebral bodies (HP:0004586)1.81531330
112Abnormality of pain sensation (HP:0010832)1.81121101
113Impaired pain sensation (HP:0007328)1.81121101
114Down-sloping shoulders (HP:0200021)1.80950856
115Steppage gait (HP:0003376)1.80435475
116Nasal speech (HP:0001611)1.79685384
117Concave nail (HP:0001598)1.78640948
118Depression (HP:0000716)1.78499128
119Bronchomalacia (HP:0002780)1.77575492
120Open mouth (HP:0000194)1.77347435
121Hepatoblastoma (HP:0002884)1.77221166
122Flat cornea (HP:0007720)1.76428976
123Pachygyria (HP:0001302)1.76255658
124Cutaneous syndactyly (HP:0012725)1.74304925
125Blue sclerae (HP:0000592)1.73821922
126Coronal craniosynostosis (HP:0004440)1.73216639
127Renovascular hypertension (HP:0100817)1.71814500
128Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.71170511
129Urinary bladder sphincter dysfunction (HP:0002839)1.70752124
130Pelvic girdle muscle weakness (HP:0003749)1.70216154
131Sudden death (HP:0001699)1.68970143
132Difficulty running (HP:0009046)1.68539255
133Hyperthyroidism (HP:0000836)1.65782987
134Poor eye contact (HP:0000817)1.65583117
135Poor suck (HP:0002033)1.65498773
136Scapular winging (HP:0003691)1.64418808
137Cervical subluxation (HP:0003308)1.63704983
138Abnormality of the hip-girdle musculature (HP:0001445)1.63551061
139Abnormality of the musculature of the pelvis (HP:0001469)1.63551061
140Abnormality of salivation (HP:0100755)1.63540080
141Abnormality of oral frenula (HP:0000190)1.63007144
142Hip dysplasia (HP:0001385)1.62979084
143Myotonia (HP:0002486)1.62639462
144Thoracolumbar scoliosis (HP:0002944)1.62364610
145Absent speech (HP:0001344)1.62348278
146Limb-girdle muscle atrophy (HP:0003797)1.61171748
147Breech presentation (HP:0001623)1.61075915
148Round ear (HP:0100830)1.60470445
149Megalocornea (HP:0000485)1.60380036
150Pointed chin (HP:0000307)1.59646669
151Impaired vibration sensation in the lower limbs (HP:0002166)1.59191046
152Dialeptic seizures (HP:0011146)1.58856426
153Ulnar bowing (HP:0003031)1.58819032
154Hemiparesis (HP:0001269)1.57948374
155Lower limb amyotrophy (HP:0007210)1.57566682
156Cortical dysplasia (HP:0002539)1.57116017
157Aplasia involving bones of the extremities (HP:0009825)1.56622942
158Aplasia involving bones of the upper limbs (HP:0009823)1.56622942
159Aplasia of the phalanges of the hand (HP:0009802)1.56622942
160Gait imbalance (HP:0002141)1.56479924
161Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.56428808
162Aortic valve stenosis (HP:0001650)1.55808906
163Morphological abnormality of the middle ear (HP:0008609)1.55555660
164Mesomelia (HP:0003027)1.54728490
165Round face (HP:0000311)1.54384353
166Elfin facies (HP:0004428)1.53437634
167Vertebral arch anomaly (HP:0008438)1.51317908
168Dilatation of the ascending aorta (HP:0005111)1.50663934
169Broad long bones (HP:0005622)1.50533161
170Elbow flexion contracture (HP:0002987)1.50357746

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.58932695
2MAP3K94.43748537
3SIK33.29883050
4EPHB22.97450717
5KSR12.95095781
6BCR2.72028755
7NTRK22.57729237
8MINK12.47676332
9NTRK32.41179654
10WNK32.15464283
11MYLK1.92691723
12TYRO31.92042124
13LATS21.91685569
14AKT31.89253354
15DYRK21.88771095
16PAK61.84087073
17MAP3K41.82951747
18FGFR21.77235072
19NTRK11.74433257
20UHMK11.68304764
21PHKG11.67391504
22PHKG21.67391504
23LMTK21.61487034
24TESK11.60470363
25MAP3K61.59226633
26MAPK131.59096551
27MAP2K71.52835656
28KSR21.51420488
29CASK1.44286538
30PAK21.42390242
31DDR21.41368493
32LIMK11.40881035
33ERBB31.40436567
34ICK1.40283393
35FER1.37116535
36MAP4K21.32099699
37GRK51.30328297
38PDGFRA1.28914476
39CDK51.23537402
40PRKD31.22585712
41MAP3K121.14469740
42IRAK21.12035327
43TNIK1.11894536
44PINK11.08251394
45EPHA41.07928685
46DAPK21.06538404
47CDK181.05193785
48MAP2K41.05079001
49TTN1.04625731
50RET1.03798269
51MAP3K21.03260373
52DYRK31.00036460
53LATS10.99686406
54PNCK0.99685204
55PRKD20.99109543
56PAK30.98995688
57PKN20.95649049
58ERBB20.94146023
59SIK20.93520628
60CDK140.93220824
61MET0.92098268
62FLT30.86902857
63CDK150.85866149
64ERBB40.80587889
65CSNK1G20.79544729
66PIM20.78578790
67PDGFRB0.77935409
68MATK0.74573291
69CDK11A0.74273114
70PRKCZ0.73399427
71NEK90.72379155
72CDK190.71945185
73RPS6KA20.71344356
74BMPR1B0.70674729
75PRKCE0.68841989
76CLK10.68308931
77ROCK10.67538911
78CAMK2B0.67363784
79MAPK150.67042238
80MAP2K10.66810044
81MARK20.66274641
82CAMK2G0.62756748
83CAMK1G0.62229331
84NME10.61666923
85DYRK1A0.61563433
86CSNK1A1L0.60705758
87EPHA30.60005783
88PRKCG0.59928222
89STK380.59166535
90CSNK1G30.58938009
91TRIM280.58207669
92ABL20.53855487
93PLK20.53082050
94CAMK2A0.52224709
95ARAF0.51955690
96CAMK2D0.51648417
97CDC42BPA0.50107643
98STK110.49214562
99DMPK0.48954372
100ADRBK10.47503700
101CAMKK10.47500593
102PTK20.46106893
103PRKCH0.45503190
104IRAK10.44248520
105RIPK10.43968638
106MTOR0.43843997
107GRK70.43348186
108MST1R0.42583134
109CAMK10.41927578
110STK240.40555461
111CSNK1G10.40378640
112SGK2230.40022114
113SGK4940.40022114
114PRKD10.39990370
115MOS0.39821404
116SIK10.37842409
117WNK10.37596386
118MAPK90.36129051
119FGFR40.35230184
120ROCK20.34782454
121CAMK1D0.33493331
122FGR0.33200317
123VRK10.33119325
124DYRK1B0.32544916
125PRKAA10.32021019
126ERN10.31609344
127FYN0.31556345
128MAP2K20.30908141
129RIPK40.30179626
130CAMK40.29102452
131SRC0.28946112
132MAP2K60.28105652
133FGFR10.27936515
134SGK10.27522097

Predicted pathways (KEGG)

RankGene SetZ-score
1Axon guidance_Homo sapiens_hsa043602.38491049
2Synaptic vesicle cycle_Homo sapiens_hsa047212.23251690
3Nicotine addiction_Homo sapiens_hsa050332.22046804
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.96885338
5Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.94862436
6ECM-receptor interaction_Homo sapiens_hsa045121.91830764
7Insulin secretion_Homo sapiens_hsa049111.81272308
8Dopaminergic synapse_Homo sapiens_hsa047281.79582118
9Circadian entrainment_Homo sapiens_hsa047131.71526892
10Glutamatergic synapse_Homo sapiens_hsa047241.65263876
11Cholinergic synapse_Homo sapiens_hsa047251.64199806
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.62621589
13GABAergic synapse_Homo sapiens_hsa047271.62247179
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.61851031
15Cocaine addiction_Homo sapiens_hsa050301.57383380
16Olfactory transduction_Homo sapiens_hsa047401.56164501
17Amphetamine addiction_Homo sapiens_hsa050311.52448469
18Long-term potentiation_Homo sapiens_hsa047201.49107956
19Gap junction_Homo sapiens_hsa045401.47004720
20Basal cell carcinoma_Homo sapiens_hsa052171.44081579
21Morphine addiction_Homo sapiens_hsa050321.43930404
22GnRH signaling pathway_Homo sapiens_hsa049121.42537217
23Melanogenesis_Homo sapiens_hsa049161.41358578
24Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.41315338
25Taste transduction_Homo sapiens_hsa047421.40112258
26ErbB signaling pathway_Homo sapiens_hsa040121.38924772
27Serotonergic synapse_Homo sapiens_hsa047261.33815257
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33709900
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.32668047
30Salivary secretion_Homo sapiens_hsa049701.32063840
31Endometrial cancer_Homo sapiens_hsa052131.30753237
32Protein digestion and absorption_Homo sapiens_hsa049741.27661946
33Hippo signaling pathway_Homo sapiens_hsa043901.27627276
34Gastric acid secretion_Homo sapiens_hsa049711.26248742
35Oxytocin signaling pathway_Homo sapiens_hsa049211.24411026
36Estrogen signaling pathway_Homo sapiens_hsa049151.24140123
37Long-term depression_Homo sapiens_hsa047301.21990412
38Glioma_Homo sapiens_hsa052141.20850701
39Renin secretion_Homo sapiens_hsa049241.16677202
40Neurotrophin signaling pathway_Homo sapiens_hsa047221.15112285
41Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.14789700
42Wnt signaling pathway_Homo sapiens_hsa043101.14536329
43Hedgehog signaling pathway_Homo sapiens_hsa043401.13498423
44Dorso-ventral axis formation_Homo sapiens_hsa043201.12148924
45Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.11164973
46Colorectal cancer_Homo sapiens_hsa052101.10771427
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07741578
48Cardiac muscle contraction_Homo sapiens_hsa042601.06711285
49VEGF signaling pathway_Homo sapiens_hsa043701.03863296
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01913674
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.01383081
52Regulation of actin cytoskeleton_Homo sapiens_hsa048100.97092963
53Type II diabetes mellitus_Homo sapiens_hsa049300.97090141
54Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.96978116
55Renal cell carcinoma_Homo sapiens_hsa052110.96315384
56Choline metabolism in cancer_Homo sapiens_hsa052310.95208549
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93133393
58Calcium signaling pathway_Homo sapiens_hsa040200.92666498
59PI3K-Akt signaling pathway_Homo sapiens_hsa041510.92405067
60Dilated cardiomyopathy_Homo sapiens_hsa054140.91101856
61Vibrio cholerae infection_Homo sapiens_hsa051100.89371219
62Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87149105
63Phospholipase D signaling pathway_Homo sapiens_hsa040720.85141402
64cAMP signaling pathway_Homo sapiens_hsa040240.84754136
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84439758
66Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83310209
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82992085
68Adherens junction_Homo sapiens_hsa045200.82803815
69Sphingolipid signaling pathway_Homo sapiens_hsa040710.82343092
70MAPK signaling pathway_Homo sapiens_hsa040100.82204273
71Notch signaling pathway_Homo sapiens_hsa043300.81899155
72cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81807538
73Oocyte meiosis_Homo sapiens_hsa041140.80858597
74Phototransduction_Homo sapiens_hsa047440.80756635
75Collecting duct acid secretion_Homo sapiens_hsa049660.79809758
76Pancreatic secretion_Homo sapiens_hsa049720.79348807
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78485630
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.78422471
79Tight junction_Homo sapiens_hsa045300.77661690
80Ras signaling pathway_Homo sapiens_hsa040140.77565205
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77441833
82Rap1 signaling pathway_Homo sapiens_hsa040150.77203277
83AMPK signaling pathway_Homo sapiens_hsa041520.75970573
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.73688290
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.73642587
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.73564042
87Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.73089624
88Pathways in cancer_Homo sapiens_hsa052000.72957005
89TGF-beta signaling pathway_Homo sapiens_hsa043500.72784740
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71894630
91mTOR signaling pathway_Homo sapiens_hsa041500.71735801
92Endocytosis_Homo sapiens_hsa041440.70908299
93Proteoglycans in cancer_Homo sapiens_hsa052050.68370265
94Circadian rhythm_Homo sapiens_hsa047100.67631263
95Insulin signaling pathway_Homo sapiens_hsa049100.66701279
96Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64978035
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.63831790
98Viral myocarditis_Homo sapiens_hsa054160.62697296
99Vascular smooth muscle contraction_Homo sapiens_hsa042700.62092639
100Prolactin signaling pathway_Homo sapiens_hsa049170.62033704
101Melanoma_Homo sapiens_hsa052180.61716263
102Amoebiasis_Homo sapiens_hsa051460.61437356
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61367750
104Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58107327
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.57406276
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56529359
107Prion diseases_Homo sapiens_hsa050200.56511494
108Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.56236439
109Bladder cancer_Homo sapiens_hsa052190.56077745
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55656256
111MicroRNAs in cancer_Homo sapiens_hsa052060.55543673
112Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55543598
113Non-small cell lung cancer_Homo sapiens_hsa052230.55284387
114Thyroid hormone synthesis_Homo sapiens_hsa049180.52991706
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52768264
116Salmonella infection_Homo sapiens_hsa051320.52375725
117Alcoholism_Homo sapiens_hsa050340.52046288
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51945780
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51102233
120Focal adhesion_Homo sapiens_hsa045100.50705433
121Phagosome_Homo sapiens_hsa041450.50341954
122Shigellosis_Homo sapiens_hsa051310.45786499
123Steroid biosynthesis_Homo sapiens_hsa001000.45549543

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »